Column chromatography separation equipment

Abstract

The utility model discloses column chromatography separation equipment which comprises a chromatographic column lower end, a communication suite is mounted at the chromatographic column lower end, the communication suite consists of a plurality of upper-end column bodies, the plurality of upper-end column bodies are detachably arranged, and the chromatographic column lower end and the upper-end column bodies are detachably arranged; first threaded openings are formed in the top of the inner wall of the lower end of the chromatographic column and the top of the inner wall of an upper-end column body, a threaded connector is fixed to the bottom of the upper-end column body and matched with the first threaded openings, an insertion groove is formed in the bottom of the outer wall of the upper-end column body, and a sealing disc is inserted into the insertion groove. First threaded openings are formed in the first threaded opening and the second threaded opening, first threaded openings are formed in the column body at the lower end and the column body at the upper end of the chromatographic column, and a threaded connector is fixed at the bottom of the column body at the upper end of the chromatographic column. According to the utility model, the column body at the lower end and the column body at the upper end of the chromatographic column can be disassembled and assembled in a threaded connection manner, and can be disassembled and segmented in a short time for sampling after separation.

Description

TECHNICAL FIELD

[0001] The utility model relates to separating equipment technical field especially, relates to a column chromatography separating equipment. BACKGROUND

[0002] Chromatography separation refers to the different partition coefficients of different substances in the system formed by the fixed phase and the mobile phase, different retention times are presented in the elution process using the mobile phase, thereby realizing separation.

[0003] Traditional chromatography separation includes sample loading, elution, separation and reception, wherein the separated samples need to be discharged from the bottom separation nozzle one by one, and the layered samples need to be sampled one by one, which consumes a long time and needs to be improved, and a column chromatography separating equipment is designed. UTILITY MODEL CONTENT

[0004] The utility model discloses a column chromatography separating equipment to solve the shortcomings in the prior art.

[0005] In order to realize the above-mentioned purpose, the utility model adopts the following technical scheme:

[0006] A column chromatography separating equipment, comprising a funnel head, the funnel head is installed with a communication suite, and the communication suite is composed of a plurality of columns, and the plurality of columns can be detachably arranged between each other, the funnel head and the column can be detachably arranged.

[0007] The inner wall top of the funnel head and the inner wall top of the column are provided with first threaded openings, the bottom of the column is fixedly provided with a threaded connector, the threaded connector is matched with the first threaded opening, the outer wall bottom of the column is provided with a slot, and a sealing disc is inserted into the slot.

[0008] As a further scheme of the utility model, the first threaded opening and the second threaded opening are provided with first threaded openings, the first threaded openings are arranged on the funnel head and the column, the threaded connector is fixedly arranged at the bottom of the column, the plurality of columns can be detachably arranged, the funnel head and the column can be detachably arranged, and the detachable arrangement is realized in the threaded connection mode.

[0009] As a further scheme of the utility model, the size of the slot is half of the circumference of the column, and the sealing disc is matched with the inner diameter of the column.

[0010] As a further scheme of the utility model, the outer wall of the sealing disc is fixedly provided with a plugging plate, the outer wall of the plugging plate is fixedly provided with a sealing sleeve, and the plugging plate and the sealing sleeve are matched with the slot.

[0011] As a further scheme of the utility model, the sealing disc is provided with a leakage hole in the center, and the sealing disc is provided with a cavity, and the sealing disc is provided with a sealing element at the leakage hole.

[0012] As a further scheme of the utility model, the sealing element comprises a plugging disc in the sealing disc, and the plugging disc is provided corresponding to the leakage hole, the plugging disc is fixed with a connecting rod, the outer wall of the plugging plate is fixed with a connecting block, the connecting block and the outer wall of the plugging plate are provided with a hole for the connecting rod to pass through, the outer end of the connecting rod is fixed with a pressing cap, and a spring is arranged between the pressing cap and the connecting block.

[0013] The utility model discloses the beneficial effects are:

[0014] The utility model discloses: because adopt the funnel head, a plurality of cylinders, sealing ring, slot, sealing disc, plugging board, sealing sleeve, plugging board and connecting block etc. are set up, wherein the first threaded mouth is set up on the funnel head and the cylinder, and the threaded connector is fixed at the bottom of the cylinder, a plurality of cylinders can be disassembled, and the funnel head and the cylinder can be disassembled, and the first threaded mouth and the sealing sleeve are set up and play certain sealing effect in the threaded connection mode.

[0015] The utility model discloses: the sealing element is set up, including plugging disc, connecting rod and spring, when the sample is adsorbed, the leakage hole is in the open state, and the sealing element does not block the leakage hole, so that the cylinder and the funnel head are communicated, and the flow between liquid is convenient, when the sample is taken after separation, first press, make the spring compression, make the plugging disc of connecting rod seal leakage hole, prevent liquid from leaking when disassembling the cylinder, after the cylinder is to the position of the graduated cylinder, release the restriction to the spring, make the plugging disc separate the leakage hole, and the liquid in the cylinder is discharged through the leakage hole, and only needs short time to disassemble the section, and takes the sample after separation. ACCURACY OF DRAWINGS

[0016] Figure 1 A three-dimensional structural schematic view of the column chromatography separation equipment is provided for the utility model;

[0017] Figure 2 A partially expanded three-dimensional structural schematic view of the column chromatography separation equipment is provided for the utility model;

[0018] Figure 3 A partially expanded three-dimensional structural schematic view of the cylinder of the column chromatography separation equipment is provided for the utility model;

[0019] Figure 4 A three-dimensional structural schematic view of the column chromatography separation equipment is provided for the utility model; Figure 3 A partially sectional three-dimensional structural schematic view of the column chromatography separation equipment is provided for the utility model.

[0020] In the figure: 1, funnel head; 101, first threaded port; 2, column body; 3, sealing ring; 4, threaded connector; 5, second threaded port; 6, insertion slot; 7, sealing disc; 8, blocking plate; 9, sealing sleeve; 11, connecting block; 12, leakage hole; 13, sealing element; 131, blocking disc; 132, connecting rod; 133, spring. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments.

[0022] It should be noted that the embodiments in the present application and the features in the embodiments can be combined with each other without conflict. The utility model will be described in detail below with reference to the drawings and in combination with the embodiments.

[0023] Reference Figures 1-4 A column chromatography separation device includes a funnel head 1, the funnel head 1 is provided with a communication assembly, and the communication assembly is composed of a plurality of column bodies 2, and the plurality of column bodies 2 can be detachably arranged with each other, and the funnel head 1 and the column body 2 can be detachably arranged.

[0024] The inner wall top of the funnel head 1 and the inner wall top of the column body 2 are both provided with a first threaded port 101, the bottom of the column body 2 is fixedly provided with a threaded connector 4, the threaded connector 4 is matched with the first threaded port 101, the outer wall bottom of the column body 2 is provided with an insertion slot 6, and the insertion slot 6 is inserted with a sealing disc 7.

[0025] In the embodiment, the first threaded port 101 and the second threaded port 5 are both provided with the first threaded port 101, the first threaded port 101 is arranged on the funnel head 1 and the column body 2, the threaded connector 4 is fixedly arranged at the bottom of the column body 2, the plurality of column bodies 2 can be detachably arranged with each other, and the funnel head 1 and the column body 2 can be detachably arranged.

[0026] In the embodiment, the insertion slot 6 is provided with a size of half of the circumference of the column body 2, and the sealing disc 7 is matched with the inner diameter of the column body 2.

[0027] In the embodiment, the outer wall of the sealing disc 7 is fixedly provided with a blocking plate 8, the outer wall of the blocking plate 8 is fixedly provided with a sealing sleeve 9, and the blocking plate 8 and the sealing sleeve 9 are matched with the insertion slot 6.

[0028] In the embodiment, the center of the sealing disc 7 is provided with a leakage hole 12, and the sealing disc 7 is provided as a cavity, and the sealing element 13 is arranged in the sealing disc 7 at the leakage hole 12.

[0029] In this embodiment, the sealing member 13 comprises a blocking disc 131 located in the sealing disc 7, and the blocking disc 131 is provided corresponding to the leakage hole 12, the blocking disc 131 is fixed with a connecting rod 132, the outer wall of the blocking plate 10 is fixed with a connecting block 11, the connecting block 11 and the outer wall of the blocking plate 10 are provided with holes for the connecting rod 132 to pass through, the outer end of the connecting rod 132 is fixed with a pressing cap, and the pressing cap and the connecting block 11 are provided with a spring 133.

[0030] Working principle: through the setting of the funnel head 1, the plurality of columns 2, the sealing ring 3, the slot 6, the sealing disc 7, the blocking plate 8, the sealing sleeve 9, the blocking plate 10 and the connecting block 11, wherein the first threaded port 101 is arranged on the funnel head 1 and the column 2, the threaded connecting head 4 is fixed at the bottom of the column 2, the plurality of columns 2 can be disassembled, the funnel head 1 and the column 2 can be disassembled, the disassembly is realized in a threaded connection manner, and the first threaded port 101 and the sealing sleeve 9 both have a certain sealing effect, the sealing member 13 is provided, including the blocking disc 131, the connecting rod 132 and the spring 133, when the sample is adsorbed, the leakage hole 12 is in an open state, the sealing member 13 does not block the leakage hole 12, so that the column 2 and the funnel head 1 are the same, facilitating the flow between the liquids, when the sample is taken after separation, first press to compress the spring 133, so that the connecting rod 132 connects the blocking disc 131 to block the leakage hole 12, to prevent liquid from leaking out when the column 2 is disassembled, after the column 2 reaches the position of the graduated cylinder, the spring 133 is released to limit the spring 133, so that the blocking disc 131 is separated from the leakage hole 12, and the liquid in the column 2 is discharged through the leakage hole 12, which can be disassembled and segmented only for a short time, and the sample is taken after separation.

[0031] For the sake of convenience, spatially relative terms, such as "beneath", "below", "lower", "above", "upper" and the like, can be used herein for ease of description to describe one element or feature's relationship to another element(s) or feature(s) as illustrated in the various figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientations depicted in the figures. For example, if a device in the figures is inverted, elements described as "below" or "beneath" other elements or features would then be oriented "above" and "over" the other elements or features. Thus, the exemplary term "below" can encompass both an orientation of below and above. The device can be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly. Well-known functions or constructions can not be described in detail for brevity.

[0032] It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and / or "comprising," when used in this specification, specify the presence of stated features, steps, operations, devices, components and / or combinations thereof, but do not preclude the presence or addition of one or more other features, steps, operations, devices, components and / or combinations thereof.

[0033] The preferred embodiments of the present application have been described above with the aid of drawing provided only by way of example and therefore changes in form and detail can be made without departing from the spirit and scope of the application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the scope of the present application.

Claims

1. A column chromatography separation apparatus comprising a funnel head (1), characterized in that, The funnel head (1) is provided with a communication set, and the communication set is composed of a plurality of columns (2) which can be detachably arranged with each other. The inner wall top of the funnel head (1) and the inner wall top of the column (2) are provided with first threaded openings (101), the bottom of the column (2) is fixedly provided with a threaded connector (4), the threaded connector (4) is matched with the first threaded opening (101), the outer wall bottom of the column (2) is provided with a slot (6), and the slot (6) is inserted with a sealing disc (7).

2. A column chromatography apparatus according to claim 1, wherein The first threaded opening (101) and the second threaded opening (5) are provided with the first threaded opening (101).

3. A column chromatography apparatus according to claim 1, wherein The size of the slot (6) is half of the circumference of the column (2), and the sealing disc (7) is matched with the inner diameter of the column (2).

4. A column chromatography apparatus according to claim 1, wherein The outer wall of the sealing disc (7) is fixedly provided with a sealing plate (8), the outer wall of the sealing plate (8) is fixedly provided with a sealing sleeve (9), and the sealing plate (8) and the sealing sleeve (9) are matched with the slot (6).

5. A column chromatography apparatus according to claim 4, wherein The center of the sealing disc (7) is provided with a leakage hole (12), and the sealing disc (7) is provided as a cavity, and the sealing disc (7) is provided with a sealing element (13) at the leakage hole (12).

6. A column chromatography apparatus according to claim 5, wherein The sealing element (13) comprises a sealing disc (131) in the sealing disc (7), and the sealing disc (131) is arranged corresponding to the leakage hole (12), the sealing disc (131) is fixedly provided with a connecting rod (132), the outer wall of the sealing plate (8) is fixedly provided with a connecting block (11), the outer wall of the sealing plate (8) and the connecting block (11) are provided with holes for the connecting rod (132) to pass through, and the outer end of the connecting rod (132) is fixedly provided with a pressing cap, and the pressing cap and the connecting block (11) are provided with a spring (133).

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