High-pressure reverse osmosis concentration device for purification of anidulafungin

Abstract

The purification high-pressure reverse osmosis concentration device comprises a barrel, the left side of the barrel is open, a threaded groove is formed in the left side of the barrel, the inner wall of the threaded groove is in threaded connection with a sealing plate, the right side of the sealing plate is fixedly connected with connecting rods which are distributed in an annular mode, and the connecting rods are fixedly connected with the left side of the barrel. A piston plate is slidably connected to the inner wall of the cylinder body, the left side of the piston plate is fixedly connected with the connecting rod, a through hole is formed in the piston plate, a mounting groove is formed in the inner wall of the through hole, a reverse osmosis membrane body is in threaded connection with the inner wall of the mounting groove, and a feeding pipe is communicated with the top of the cylinder body. According to the reverse osmosis membrane cleaning device, when the reverse osmosis membrane body is cleaned, the reverse osmosis membrane body is very easily detached, the cleaning difficulty of the reverse osmosis membrane body is effectively reduced, the inner wall of the barrel can be automatically cleaned in the process of detaching the reverse osmosis membrane body, and the practicability of the device is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to anifrolumab purification preparation technical field, concretely is a kind of anifrolumab's purification high pressure reverse osmosis concentration device. BACKGROUND

[0002] Anifrolumab's purification high pressure reverse osmosis concentration device is a kind of equipment for anifrolumab production process, the solution containing anifrolumab is purified and concentrated treatment.This device mainly utilizes reverse osmosis technology, can effectively separate anifrolumab and other impurities, solvent etc in solution, improve the purity and concentration of anifrolumab, to meet subsequent production process requirements.

[0003] Anifrolumab's purification high pressure reverse osmosis concentration device when in use, with the increase of running time, membrane surface will adsorb some pollutants, such as organic matter, microorganism etc., lead to membrane performance to drop, thus need to clean membrane regularly, but traditional membrane is usually fixed in device interior, it is very difficult for user to disassemble, increase the difficulty of user to clean membrane. SUMMARY

[0004] In view of the problems in the prior art, the utility model aims at providing anifrolumab's purification high pressure reverse osmosis concentration device to solve the problems in the background art.

[0005] To achieve the above-mentioned purpose, the utility model adopts the following technical scheme:

[0006] Anifrolumab's purification high pressure reverse osmosis concentration device, including cylinder, the left side of the cylinder is set to be open, the left side of the cylinder is equipped with screw groove, the inner wall of the screw groove is connected with the sealing plate, the right side of the sealing plate is fixedly connected with the annular distribution connecting rod, the inner wall of the cylinder is slidably connected with the piston plate, the left side of the piston plate is fixedly connected with the connecting rod, the piston plate is equipped with through-hole, the inner wall of the through-hole is equipped with installation groove, the inner wall of the installation groove is connected with the reverse osmosis membrane body, the top of the cylinder is connected with the feed pipe, the right side of the cylinder is connected with the discharge pipe, and the water pump is installed on the feed pipe.

[0007] Further description of the above technical scheme:

[0008] The inner wall of the screw groove is fixedly connected with the sealing ring, and the left side of the sealing ring is in contact with the sealing plate.

[0009] Further description of the above technical scheme:

[0010] The inner wall of the cylinder is fixedly connected with the sealing ring, and the left side of the sealing ring is in contact with the reverse osmosis membrane body.

[0011] Further description of the above technical scheme:

[0012] The right end of the feeding pipe is communicated with a box body, the right side of the box body is communicated with a guide pipe, and the top of the box body is inserted with a filter plate in sliding connection with the box body.

[0013] As a further description of the above technical solution:

[0014] The top and the bottom of the box body are respectively communicated with water pipes, and electromagnetic valves are installed on the two water pipes and the feeding pipe.

[0015] As a further description of the above technical solution:

[0016] A sliding groove is formed in the box body, a locking rod is in sliding connection with the inner wall of the sliding groove, a spring is fixedly connected to the right side of the locking rod, the right end of the spring is fixedly connected to the box body, and a lock hole matched with the locking rod is formed in the right side of the filter plate.

[0017] Compared with the prior art, the present application has the following advantages:

[0018] The present application can easily dismount the reverse osmosis membrane body when cleaning the reverse osmosis membrane body, effectively reduces the difficulty of cleaning the reverse osmosis membrane body, and can automatically clean the inner wall of the cylinder during the dismounting process, thereby improving the practicability of the device. BRIEF DESCRIPTION OF DRAWINGS

[0019] Figure 1 It is a perspective view of the present application;

[0020] Figure 2 It is a perspective view of the present application;

[0021] Figure 3 It is a sectional view of the present application;

[0022] Figure 4 It is a perspective view of the present application Figure 3 It is an enlarged view of part A of the present application.

[0023] Explanation of reference numerals in the drawing:

[0024] 1, cylinder; 2, threaded groove; 3, sealing plate; 4, connecting rod; 5, piston plate; 6, through hole; 7, mounting groove; 8, reverse osmosis membrane body; 9, feeding pipe; 10, discharging pipe; 11, water pump; 12, sealing ring; 13, sealing ring; 14, box body; 15, guide pipe; 16, filter plate; 17, water pipe; 18, electromagnetic valve; 19, sliding groove; 20, locking rod; 21, spring; 22, lock hole. DETAILED DESCRIPTION

[0025] The technical scheme in the embodiments of the utility model will be described clearly and completely in connection with the drawings in the embodiments of the utility model.

[0026] Please refer to Figures 1-4 The utility model discloses: a kind of purification high-pressure reverse osmosis concentration device of anidulafungin, including cylinder 1, the left side of cylinder 1 is set to open, the left side of cylinder 1 is provided with screw groove 2, the inner wall of screw groove 2 is connected with sealing plate 3 by screwing, the right side of sealing plate 3 is fixedly connected with the connecting rod 4 of annular distribution, the inner wall of cylinder 1 is slidably connected with piston plate 5, the left side of piston plate 5 is fixedly connected with connecting rod 4, through hole 6 is set on piston plate 5, installation groove 7 is set on the inner wall of through hole 6, the inner wall of installation groove 7 is connected with reverse osmosis membrane body 8 by screwing, the top of cylinder 1 is communicated with feed pipe 9, the right side of cylinder 1 is communicated with discharge pipe 10, water pump 11 is installed on feed pipe 9.

[0027] In the utility model, when using, first, water pump 11 opens and adds the solution of anidulafungin into cylinder 1 through feed pipe 9, then the solution of anidulafungin will pass through reverse osmosis membrane body 8, reverse osmosis membrane body 8 has selective permeability, only allows water and other small molecule solvents to permeate, while anidulafungin and other macromolecular impurities, ions, etc. are intercepted on the feed side of the membrane, under the action of high pressure, solvent continuously permeates the membrane and enters the permeate side, thereby realizing the concentration of solution, while removing most of the impurities, achieving the purpose of purifying anidulafungin, as the running time increases, when reverse osmosis membrane body 8 needs to be cleaned, the user only needs to rotate sealing plate 3, sealing plate 3 will rotate down from screw groove 2, then the user pulls sealing plate 3 outward, sealing plate 3 will drive piston plate 5 to slide out of cylinder 1 through connecting rod 4, in the process, piston plate 5 will scrape off the dirt adhered to the inner wall of cylinder 1, until piston plate 5 slides out of the inside of cylinder 1, the effect of cleaning the inner wall of cylinder 1 can be realized, at this time, reverse osmosis membrane body 8 will also be taken out of cylinder 1, the user only needs to rotate reverse osmosis membrane body 8, which can be rotated down from installation groove 7, then reverse osmosis membrane body 8 can be cleaned, the process is very convenient and fast, effectively reduces the difficulty of cleaning reverse osmosis membrane body 8, and in the process of disassembling reverse osmosis membrane body 8, the automatic cleaning of the inner wall of cylinder 1 can be realized, improving the practicability of the device.

[0028] Please refer to Figure 3 Among them: the inner wall of screw groove 2 is fixedly connected with sealing ring 12, the left side of sealing ring 12 is in contact with sealing plate 3.

[0029] In the utility model, the sealing ring 12 can improve the sealing effect between the sealing plate 3 and the screw groove 2, avoid the solution leakage, and improve the practicability of the device.

[0030] Please refer to Figure 3In this case, a sealing ring 13 is fixedly connected to the inner wall of the cylinder 1, and the left side of the sealing ring 13 is in contact with the reverse osmosis membrane body 8.

[0031] In this invention, the sealing ring 13 is designed to ensure that the reverse osmosis membrane body 8 is tightly attached to the sealing ring 13 during installation. This allows the reverse osmosis membrane body 8 to be pressed between the sealing ring 13 and the piston plate 5, thereby improving the stability of the reverse osmosis membrane body 8 installation. It also prevents the solution from flowing into the right side of the cylinder 1 through the gap without passing through the reverse osmosis membrane body 8, thus improving the practicality of the device.

[0032] Please see Figures 1-4 The feed pipe 9 is connected to the box 14 at its right end, the box 14 is connected to the conduit 15 on its right side, and the top of the box 14 is slidably connected to the filter plate 16.

[0033] In this invention, when the solution enters the inner wall of the cylinder 1, it first enters the box 14 through the conduit 15, and then passes through the filter plate 16. The filter plate 16 pre-treats the solution, filtering out large particulate impurities in the solution, thus preventing large particulate impurities from clogging the reverse osmosis membrane body 8 and extending the cleaning cycle of the reverse osmosis membrane body 8.

[0034] Please see Figures 1-3 The top and bottom of the housing 14 are connected to water pipes 17, and solenoid valves 18 are installed on both water pipes 17 and the feed pipe 9.

[0035] In this invention, after running for a period of time, particulate matter will adhere to the surface of the filter plate 16. The user closes the solenoid valve 18 on the feed pipe 9 and opens the solenoid valves 18 on the two water pipes 17. At this time, water is added to the box 14 from the top water pipe 17. The water will pass through the filter plate 16 in the reverse direction and be discharged from the bottom water pipe 17. During the process, the water can achieve the effect of backwashing and cleaning the filter plate 16, thus achieving the effect of automatic cleaning of the filter plate 16.

[0036] Please see Figure 4 The box body 14 is provided with a sliding groove 19, and a locking rod 20 is slidably connected to the inner wall of the sliding groove 19. A spring 21 is fixedly connected to the right side of the locking rod 20, and the right end of the spring 21 is fixedly connected to the box body 14. A lock hole 22 that matches the locking rod 20 is provided on the right side of the filter plate 16.

[0037] In this invention, the locking rod 20 can be inserted into the lock hole 22 to lock the filter plate 16, thereby improving the stability of the device. When maintaining the filter plate 16, the user only needs to pull the locking rod 20 to the right until the locking rod 20 slides out of the lock hole 22. At this time, the filter plate 16 can be pulled out for maintenance, which is very convenient and quick.

[0038] The above merely describes the preferred embodiments of the present application; however, the protection scope of the present application is not limited thereto. Any person skilled in the art, within the technical range disclosed by the present application, according to the technical scheme and improvement concept of the present application, makes equivalent replacement or change, which should be covered in the protection scope of the present application.

Claims

1. A high-pressure reverse osmosis concentration apparatus for purifying anisfenamic acid, comprising a cylindrical body (1), characterized in that: The left side of the cylinder (1) is open, and a threaded groove (2) is provided on the left side of the cylinder (1). A sealing plate (3) is threadedly connected to the inner wall of the threaded groove (2). A connecting rod (4) distributed in a ring is fixedly connected to the right side of the sealing plate (3). A piston plate (5) is slidably connected to the inner wall of the cylinder (1). The left side of the piston plate (5) is fixedly connected to the connecting rod (4). A through hole (6) is provided on the piston plate (5). An installation groove (7) is provided on the inner wall of the through hole (6). A reverse osmosis membrane body (8) is threadedly connected to the inner wall of the installation groove (7). A feed pipe (9) is connected to the top of the cylinder (1). A discharge pipe (10) is connected to the right side of the cylinder (1). A water pump (11) is installed on the feed pipe (9).

2. The high-pressure reverse osmosis concentration apparatus for purifying anisulfenac according to claim 1, characterized in that: A sealing ring (12) is fixedly connected to the inner wall of the threaded groove (2), and the left side of the sealing ring (12) is in contact with the sealing plate (3).

3. The high-pressure reverse osmosis concentration apparatus for purifying anisulfenac according to claim 1, characterized in that: A sealing ring (13) is fixedly connected to the inner wall of the cylinder (1), and the left side of the sealing ring (13) is in contact with the reverse osmosis membrane body (8).

4. The high-pressure reverse osmosis concentration apparatus for purifying anisulfenac according to claim 1, characterized in that: The right end of the feed pipe (9) is connected to a box (14), the right side of the box (14) is connected to a conduit (15), and a filter plate (16) is inserted through the top of the box (14) and slidably connected thereto.

5. The high-pressure reverse osmosis concentration apparatus for purifying anisulfenac according to claim 4, characterized in that: The top and bottom of the box (14) are respectively connected to water pipes (17), and solenoid valves (18) are installed on both water pipes (17) and the feed pipe (9).

6. The high-pressure reverse osmosis concentration apparatus for purifying anisulin according to claim 4, characterized in that: The box (14) is provided with a sliding groove (19), and a locking rod (20) is slidably connected to the inner wall of the sliding groove (19). A spring (21) is fixedly connected to the right side of the locking rod (20), and the right end of the spring (21) is fixedly connected to the box (14). A lock hole (22) adapted to the locking rod (20) is provided on the right side of the filter plate (16).

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