Novel fluorescence labeling coupling tool
By introducing a support plate and pop-up fixing structure into the fluorescent label coupling tool, combined with a label and a rotating disk, the problems of reagent contamination and inconvenient removal are solved, enabling rapid identification and safe removal of reagents, and improving experimental efficiency and accuracy.
Patent Information
- Application Number
- CN202520260828.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-19
- Publication Date
- 2025-12-26
- Estimated Expiration
- 2035-02-19
AI Technical Summary
Existing fluorescent labeling coupling tools are prone to reagent contamination when opening the cover to remove reagents, and are not convenient for quickly identifying and removing the required reagents, affecting the progress and accuracy of experimental operations.
A reagent kit including a support plate and a pop-up fixing structure was designed. The reagent bottle is held by a spring, and the design of the label and rotating disk realizes the positioning and marking of the reagent bottle, ensuring that the reagent bottle does not shake during transportation, and the required reagent can be quickly identified and taken out by the label and rotating disk.
It effectively prevents reagent contamination, improves reagent retrieval efficiency, ensures the accuracy and efficiency of experimental operations, and reduces the risk of reagent exposure.
Smart Images

Figure CN223721532U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to fluorescent labeling kit technical field more specifically, the utility model relates to a novel fluorescent labeling coupling tool. BACKGROUND
[0002] At present, in numerous scientific research and actual detection application fields, fluorescent labeling coupling technology plays a very important role, which can realize the visualization tracking, positioning and quantitative analysis of target molecules by coupling fluorescent markers with target molecules, however, when carrying out fluorescent labeling coupling operation, it is often necessary to use a variety of different fluorescent labeling reagents, therefore, the fluorescent labeling coupling kit can be used as an important tool to ensure the accuracy and efficiency of the experiment and the proper preservation of the reagent.
[0003] Through the search, the authorized announcement No. CN218520117U of China patent discloses a double fluorescent labeling cell sub-organization's kit, the structure not only can through the cooperation of limiting hole and elastic pad, make reagent tube get further fixed, improve the fixed effect of device, and can through locking mechanism, make the cover plate get quick fixed, improve the convenience of device, also can through chamfer guide reagent tube, improve the guiding effect of device.
[0004] But this structure in actual use, when opening the cover plate to take out the reagent in the reagent bottle, it is easy to cause a large amount of reagent to be exposed in the environment and cause pollution, and it is not convenient to quickly distinguish and take the reagent needed to be used, which affects the progress and accuracy of the experiment operation, in view of this, the utility model provides a novel fluorescent labeling coupling tool. UTILITY MODEL CONTENT
[0005] In order to overcome the above-mentioned defects of the prior art, the utility model provides a novel fluorescent labeling coupling tool to solve the problems raised in the background art.
[0006] In order to achieve the above-mentioned purpose, the utility model provides the following technical scheme: a novel fluorescent labeling coupling tool, comprising a reagent box for storing a plurality of fluorescent labeling reagent bottles, a support plate is fixedly installed inside the reagent box.
[0007] In order to facilitate the operator to quickly take out the corresponding reagent bottle for reagent use, avoid the pollution caused by the simultaneous extension of a plurality of reagent bottles to the outside of the reagent box, preferably, a plurality of pop-out fixing structures are arranged on the support plate, the pop-out fixing structure comprises a support seat, a mounting groove is formed in the surface of the support plate, a first spring is fixedly arranged at the bottom of the inner cavity of the mounting groove, the support seat is located inside the mounting groove and is fixedly connected with the first spring, a reagent bottle containing fluorescent labeling reagent is placed in the inside of the support seat.
[0008] The surface of the kit is provided with a rectangular opening for the reagent bottle to extend out, the surface of the kit and located on one side of the rectangular opening is provided with a sliding groove, the inner wall of the rectangular opening is provided with an extension groove which is in communication with the rectangular opening and the sliding groove, the inside of the rectangular opening is provided with a shielding plate which is matched with the structure of the rectangular opening and is slidingly connected with the kit through the extension groove, the surface of the shielding plate is fixedly provided with an identification tag for distinguishing different reagent bottles, the inside of the sliding groove is provided with a sliding block, the inside of the sliding groove located on one side of the sliding block is provided with a second spring, the sliding block is slidingly connected in the inside of the sliding groove and is fixedly connected with one end of the shielding plate, and the two ends of the second spring are connected with the sliding block and the inner wall of the sliding groove respectively.
[0009] In order to enable the operator to know whether the reagent in the reagent bottle is used or not, preferably, the top of the sliding block is fixedly provided with a mounting plate, the mounting plate is provided with a rotating disc, an axle pin is arranged between the rotating disc and the mounting plate and tightly rotates through the axle pin, the surface of the mounting plate located on both sides of the rotating disc is respectively provided with a first marker and a second marker, wherein the colors of the first marker and the second marker are different, and the outer wall of the rotating disc is fixedly provided with a indicating needle.
[0010] The technical effects and advantages of the utility model are as follows:
[0011] By setting the pop-out fixing structure, the bottom ends of the plurality of reagent bottles are located in the corresponding support seats, and the first spring in the mounting groove provides the opposite force of the reagent bottle, so that the bottom end and the top end of the reagent bottle are clamped between the support seat and the shielding plate respectively, thereby avoiding the shaking of the plurality of reagent bottles in the inside of the kit during transportation.
[0012] The information on the identification tag can facilitate the operator to know the type of the reagent in the reagent bottle, the corresponding sliding block is slid and the second spring is extruded, the sliding block drives the shielding plate to slide to the inside of the kit through the extension groove and exposes the rectangular opening, under the action of the first spring, the support seat drives the reagent bottle to extend out from the inside of the rectangular opening, thereby facilitating the taking out and use of the reagent bottle which needs to be used, avoiding the extension of the plurality of reagent bottles from the inside of the kit at the same time, causing the pollution of other reagents, and facilitating the operator to quickly take out the corresponding reagent which needs to be used, improving the efficiency of the fluorescent marking.
[0013] By rotating the rotating disc, the rotating disc is rotated on the surface of the mounting plate through the shaft pin, the rotating disc drives the indicating needle to rotate to the surface of the first marker card, the color of the first marker card can be black, indicating that the reagent in the reagent bottle has been used in a single operation, and the indicating needle can be rotated to the surface of the second marker card at other unused reagent bottles, the color of the second marker card can be white, indicating that the reagent in the reagent bottle has not been used in a single operation, thereby facilitating the operator to clearly know whether the reagent is used or not. BRIEF DESCRIPTION OF DRAWINGS
[0014] Figure 1 It is the overall structure schematic view of the utility model.
[0015] Figure 2 It is the structure schematic view when the plurality of reagent bottles are distributed on the surface of the supporting plate.
[0016] Figure 3 It is the supporting seat and first spring connecting structure schematic view of the utility model.
[0017] Figure 4 It is the specific detail enlarged structure schematic view when the shielding plate slides.
[0018] Figure 5 It is the rotating disc and mounting plate connecting structure schematic view of the utility model.
[0019] The figure mark is: 1, reagent box;2, supporting plate;3, supporting seat;4, mounting groove;5, first spring;6, rectangular port;7, sliding groove;8, extension groove;9, shielding plate;10, sliding block;11, second spring;12, identification sign;13, mounting plate;14, rotating disc;15, shaft pin;16, first marker card;17, second marker card;18, indicating needle. DETAILED DESCRIPTION
[0020] The technical scheme in the embodiments of the utility model will be described clearly and completely in combination with the drawings in the embodiments of the utility model, and obviously, the described embodiments are only part of the embodiments of the utility model, not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by the person skilled in the art without creative labor belong to the protection scope of the utility model.
[0021] As shown in the drawings Figures 1-5 A novel fluorescent marker coupling tool, comprising a reagent box 1 for storing a plurality of fluorescent marker reagent bottles, a supporting plate 2 is fixedly installed in the reagent box 1.
[0022] Specifically, in the structure, the reagent box 1 for storing a plurality of fluorescently labeled reagent bottles is a fluorescently labeled coupling tool in the utility model, specifically, a plurality of fluorescently labeled reagent bottles are stored through the reagent box 1, and subsequent operators can conveniently take out the corresponding fluorescently labeled reagent for fluorescently labeled coupling operation.
[0023] The technical points of the reagent box 1 of the application are further described below:
[0024] In the embodiment, as shown in Figs. 1, 2, 3 and 4, a plurality of pop-up fixing structures are arranged on the support plate 2, and the pop-up fixing structure comprises a support seat 3. Figure 1 、 2 The inner cavity of the installation groove 4 is fixedly provided with a first spring 5 at the bottom, the support seat 3 is located inside the installation groove 4 and is fixedly connected with the first spring 5, and the inside of the support seat 3 is placed with a reagent bottle containing fluorescently labeled reagent.
[0025] A rectangular port 6 for the reagent bottle to extend out is arranged on the surface of the reagent box 1, a sliding groove 7 is arranged on one side of the surface of the reagent box 1 and located at the rectangular port 6, an extension groove 8 is arranged on the inner wall of the rectangular port 6 and communicates with the rectangular port 6 and the sliding groove 7, a shielding plate 9 is arranged inside the rectangular port 6, the shielding plate 9 is matched with the structure of the rectangular port 6, and the shielding plate 9 is slidingly connected with the reagent box 1 through the extension groove 8, an identification tag 12 for distinguishing different reagent bottles is fixedly arranged on the surface of the shielding plate 9, a sliding block 10 is arranged inside the sliding groove 7, a second spring 11 is arranged on one side of the sliding block 10 inside the sliding groove 7, the sliding block 10 is slidingly connected inside the sliding groove 7, one end of the sliding block 10 is fixedly connected with the shielding plate 9, and the two ends of the second spring 11 are respectively connected with the sliding block 10 and the inner wall of the sliding groove 7.
[0026] Specifically, in the structure, as the technical solution of the application, first, in the initial state, the bottom ends of a plurality of reagent bottles containing fluorescently labeled coupling reagents are located inside the corresponding support seats 3, the reagent bottles are between the support seats 3 and the shielding plates 9, the first spring 5 inside the installation groove 4 provides a force opposite to the reagent bottles, so as to clamp the bottom end and the top end of the reagent bottles between the support seats 3 and the shielding plates 9, thereby avoiding the shaking of the plurality of reagent bottles inside the reagent box 1 during transportation.
[0027] The label 12 on the shield 9 records the reagent information inside each reagent bottle, making it convenient for operators to distinguish and retrieve reagents. When a corresponding reagent bottle needs to be retrieved, the information on the label 12 indicates the type of reagent inside the bottle. By sliding the corresponding slider 10 to one side, the second spring 11 is squeezed. The sliding of the slider 10 causes the shield 9 to slide through the extension groove 8 into the interior of the reagent kit 1. At this time, the rectangular opening 6 is exposed, and under the action of the first spring 5, the support 3 causes the reagent bottle to extend out from the interior of the rectangular opening 6, thus facilitating the retrieval and use of the required reagent bottle. This avoids multiple reagent bottles extending out from the interior of the reagent kit 1 at the same time, which could cause contamination of other reagents. It also allows operators to quickly retrieve the required reagent, improving the efficiency of fluorescent labeling.
[0028] After use, place the reagent bottle back inside the reagent kit 1, ensuring the bottom of the bottle is inside the support 3. Release the slider 10, and the second spring 11 will reset after being squeezed, allowing the shield 9 to re-enter the rectangular opening 6 through the extension groove 8 to shield the top of the reagent bottle. At this time, under the action of the first spring 5, the reagent bottle is once again clamped and fixed between the support 3 and the shield 9, providing good protection for the reagent inside the bottle.
[0029] In a specific embodiment, as shown in the appendix Figure 1 , 4 As shown in Figure 5, a mounting plate 13 is fixedly installed on the top of the slider 10. A rotating disk 14 is installed on the mounting plate 13. A pivot pin 15 is installed between the rotating disk 14 and the mounting plate 13, and the rotating disk 14 rotates tightly through the pivot pin 15. A first marker 16 and a second marker 17 are respectively installed on the surface of the mounting plate 13 on both sides of the rotating disk 14. The first marker 16 and the second marker 17 are different colors. An indicator needle 18 is fixedly installed on the outer wall of the rotating disk 14.
[0030] Specifically, in this structure, to facilitate operators in clearly understanding which reagents have been used and which have not, when a corresponding reagent bottle is taken out and used, the operator can rotate the rotating disk 14, causing the rotating disk 14 to rotate on the surface of the mounting plate 13 via the shaft pin 15. The rotating disk 14 drives the indicator needle 18 to rotate to the surface of the first marker 16. The first marker 16 can be black, indicating that the reagent in the reagent bottle has been used in a single operation. For other unused reagent bottles, the indicator needle 18 can be rotated to the surface of the second marker 17. The second marker 17 can be white, indicating that the reagent in the reagent bottle has not been used in a single operation.
[0031] Working principle of this utility model:
[0032] The application provides a novel fluorescent label coupling tool, which is specifically a reagent box 1 for storing a plurality of fluorescent label reagent bottles, facilitating storage of the plurality of fluorescent label reagent bottles, and thus facilitating subsequent operation personnel to perform a plurality of fluorescent label experiment operations.
[0033] After the plurality of reagent bottles are stored in the inside of the reagent box 1, when a corresponding reagent bottle needs to be taken out, the operation personnel understands the type of the reagent in the inside of the corresponding reagent bottle through the identification tag 12, and slides the corresponding sliding block 10 to one side, and makes the second spring 11 be extruded, the sliding of the sliding block 10 drives the shielding plate 9 to slide to the inside of the reagent box 1 through the extension slot 8, at this time, the rectangular opening 6 leaks out and is under the action of the first spring 5, so that the support seat 3 drives the reagent bottle to extend out from the inside of the rectangular opening 6, and thus facilitates taking out and using the reagent bottle that needs to be used, in this process, the operation personnel can rotate the rotary disc 14 to rotate the indicating needle 18 to the surface of the first marker 16, and record that the reagent has been used in a single experiment operation.
[0034] After the reagent in the inside of the reagent bottle is used, the reagent bottle can be placed in the inside of the reagent box 1 again, and the bottom end of the reagent bottle is in the inside of the support seat 3, the second spring 11 of the sliding block 10 is reset after being extruded, so that the shielding plate 9 reenters the inside of the rectangular opening 6 through the extension slot 8 to shield the top end of the reagent bottle, at this time, under the action of the first spring 5, the reagent bottle is clamped and fixed between the support seat 3 and the shielding plate 9 again, and good protection effect is achieved on the reagent in the inside of the reagent bottle.
[0035] Finally, the operation personnel rotates all the rotary discs 14 of the reagent bottles that have been used, and rotates the indicating needle 18 to the surface of the second marker 17, facilitating use and marking next time.
[0036] The above only describes preferred embodiments of the application and is not used to limit the application, and any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the application shall be included in the protection scope of the application.
Claims
1. A new fluorescent labeling coupling tool comprising a kit (1) for storing a plurality of fluorescent labeling reagent bottles, characterized in that: The inside of the kit (1) is fixedly provided with a support plate (2), and a plurality of pop-up fixing structures are arranged on the support plate (2); The pop-up fixing structure comprises a support seat (3), and a mounting groove (4) is formed in the surface of the support plate (2); a first spring (5) is fixedly arranged at the bottom of the inner cavity of the mounting groove (4); A rectangular opening (6) for extending the reagent bottle is formed in the surface of the kit (1); a sliding groove (7) is arranged on one side of the surface of the kit (1) and located at the rectangular opening (6); an extension groove (8) is formed in the inner wall of the rectangular opening (6) and communicates with the rectangular opening (6) and the sliding groove (7); a shielding plate (9) is arranged in the rectangular opening (6); a sliding block (10) is arranged in the sliding groove (7); and a second spring (11) is arranged on one side of the sliding block (10) in the sliding groove (7).
2. The novel fluorescent label coupling tool according to claim 1, characterized in that: The support seat (3) is located in the mounting groove (4) and is fixedly connected with the first spring (5); and a reagent bottle containing a fluorescently labeled reagent is placed in the support seat (3).
3. The novel fluorescent label coupling tool according to claim 1, characterized in that: The shielding plate (9) is matched with the structure of the rectangular opening (6), and is slidably connected with the kit (1) through the extension groove (8); and an identification tag (12) for distinguishing different reagent bottles is fixedly arranged on the surface of the shielding plate (9).
4. The novel fluorescent label coupling tool according to claim 1, characterized in that: The sliding block (10) is slidably connected in the sliding groove (7), and one end of the sliding block (10) is fixedly connected with the shielding plate (9); and the two ends of the second spring (11) are respectively connected with the sliding block (10) and the inner wall of the sliding groove (7).
5. The novel fluorescent label coupling tool according to claim 1, characterized by: An installation plate (13) is fixedly arranged on the top of the sliding block (10); a rotating disc (14) is arranged on the installation plate (13); an axle pin (15) is arranged between the rotating disc (14) and the installation plate (13); and the rotating disc (14) is tightly rotatable through the axle pin (15).
6. The novel fluorescent label coupling tool according to claim 5, characterized in that: First and second marker cards (16) and (17) are respectively arranged on the two sides of the rotating disc (14) on the surface of the installation plate (13); the colors of the first and second marker cards (16) and (17) are different; and an indicating needle (18) is fixedly arranged on the outer wall of the rotating disc (14).
Citation Information
Patent Citations
Kit for double-fluorescence labeled cell submechanism
CN218520117U