Portable rapid PCR amplification device
The design of the portable carrying component solves the problem of inconvenient PCR instrument carrying, enabling one-handed operation and rapid detection, improving safety and speed, and is suitable for portable PCR amplification devices.
Patent Information
- Application Number
- CN202423282786.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-30
- Publication Date
- 2025-12-26
- Estimated Expiration
- 2034-12-30
AI Technical Summary
Existing PCR instruments are designed for fixed-position use, which occupies both hands when carried, resulting in inconvenience, poor safety and speed, and difficulty in responding to emergencies.
The design incorporates portable carrying components, including a sliding plate, carrying plate, storage components, telescopic components, and limiting components, allowing for one-handed carrying and enabling quick and safe operation through storage and telescopic mechanisms.
It improves the safety and speed of carrying out the test, facilitates rapid testing and data uploading at the testing site, and enhances emergency response capabilities.
Smart Images
Figure CN223723116U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to PCR detection device technical field, concretely is a kind of portable rapid PCR amplification device. BACKGROUND
[0002] PCR technology is also called cell-free molecular cloning system or specific DNA sequence in vitro primer directed enzymatic amplification method, it is a method of in vitro enzymatic synthesis specific DNA fragment, PCR technology can specifically amplify target DNA million times, thereby greatly improve the analysis and detection ability of DNA molecule, can detect single molecule DNA or only contain 1 target DNA molecule in every 100,000 cells sample, so this method is immediately widely used and rapidly developed in molecular biology, microbiology, medicine and genetics etc.
[0003] The structure of the existing PCR instrument is designed to meet the fixed position use in laboratory, only the holding groove is arranged on the two side walls for the holding type position transfer of PCR instrument, and the holding type carrying of PCR instrument not only causes the occupation of both hands of staff, makes it difficult to deal with emergency situation, such as the handling of front obstacle or the support of handrail when descending slope, but also easily causes the acid softness of both hands of staff in long time holding process, and further affects the safety and quickness of carrying PCR instrument.
[0004] Therefore, a portable rapid PCR amplification device is needed to solve the above problems. UTILITY MODEL CONTENT
[0005] To achieve the above object, the utility model provides the following technical scheme: a portable rapid PCR amplification device, including body, still including the base frame that sets up at the bottom of body, the base frame is equipped with the carrying assembly that is convenient for carrying body;
[0006] The carrying assembly includes two sliding plates slidingly connected to the base frame, the two sliding plates are fixedly connected with connecting blocks on the side away from each other, the two connecting blocks are connected with carrying plates through storage assemblies on the side away from the sliding plates, the two carrying plates are provided with hand holes on the side wall, the base frame is provided with telescopic assemblies for retracting the two sliding plates and limiting assemblies for limiting the two carrying plates.
[0007] The two side walls of the base frame are provided with through holes, and the two sliding plates are slidingly connected to the through holes.
[0008] The storage assembly comprises two fixed plates fixedly connected to the connecting block away from the sliding plate, a storage rod arranged between the two fixed plates, a storage cloth wound on the side wall of the storage rod, one end of the storage cloth being connected with the storage rod, and the other end of the storage cloth being connected with the carrying plate, and one of the two fixed plates is provided with a winding assembly for winding the storage cloth.
[0009] The winding assembly comprises a T-shaped winding rod arranged on the fixed plate away from the storage cloth, one end of the T-shaped winding rod being connected with the storage rod, a torsional spring being sleeved on the side wall of the T-shaped winding rod, and both ends of the torsional spring being connected with the fixed plate and the side wall of the T-shaped winding rod.
[0010] The limiting assembly comprises limiting holes arranged on the opposite two inner walls of the through hole, limiting plates connected by the strong magnetic plate through the bottom walls of the two limiting holes, and opposite ends of the two limiting plates being connected with the carrying plate.
[0011] The telescopic assembly comprises a telescopic rod fixedly connected between the opposite two inner walls of the base frame, the two sliding plates being slidingly connected to the telescopic rod, and two springs being sleeved on the side wall of the telescopic rod, and both ends of the two springs being connected with the inner wall of the base frame and the sliding plate.
[0012] Compared with the prior art, the utility model has the advantages that:
[0013] The utility model discloses a carrying assembly is arranged under the cooperation of storage assembly and telescopic assembly, and staff can carry the machine body by using one hand, thereby improving the emergency treatment of sudden situation in the carrying process of the machine body, and the left and right hands are exchanged to pull, thereby reducing the falling risk caused by the softness of both hands in the carrying process of the machine body, and the safety and the quickness of carrying the machine body are improved, so that the machine body can be conveniently carried to detect the virus quickly and upload the detection data to respond to the virus quickly. ACCURATE DRAWINGS
[0014] Figure 1 It is the whole structure schematic diagram of the utility model;
[0015] Figure 2 It is the internal structure schematic diagram of the carrying assembly of the utility model;
[0016] Figure 3 It is Figure 2 It is the enlarged view of A in the middle;
[0017] Figure 4 It is the schematic diagram for carrying the machine body.
[0018] In the figure: 1, the body; 2, the base frame; 301, sliding plate; 302, connecting block; 303, carrying plate; 304, hand hole; 305, through hole; 401, fixed plate; 402, storage rod; 403, storage cloth; 501, T-shaped winding rod; 502, torsional spring; 601, limiting hole; 602, limiting plate; 701, telescopic rod; 702, spring. DETAILED DESCRIPTION
[0019] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the utility model.
[0020] Embodiment 1
[0021] Please refer to Figures 1-4 , a portable rapid PCR amplification device in the figure, including the body 1, still including the base frame 2 that sets up at the bottom of the body 1, the base frame 2 is equipped with the carrying assembly that is convenient for carrying the body 1;
[0022] The carrying assembly includes two sliding plates 301 slidingly connected to the base frame 2, the two sliding plates 301 are fixedly connected with connecting blocks 302 on the sides away from each other, the two connecting blocks 302 are connected with carrying plates 303 on the sides away from the sliding plates 301 through storage assemblies, the two carrying plates 303 are provided with hand holes 304 on the side walls, the base frame 2 is provided with telescopic assemblies for retracting the two sliding plates 301 and limiting assemblies for limiting the two carrying plates 303, the opposite two side walls of the base frame 2 are provided with through holes 305, and the two sliding plates 301 are slidingly connected to the through holes 305.
[0023] It should be noted that: through the setting of the carrying assembly, under the cooperation of the storage assembly and the telescopic assembly, the staff can carry the body 1 with one hand, thereby improving the emergency handling of sudden situations during the carrying process of the body 1 and reducing the risk of falling caused by the simultaneous softness of both hands during the carrying process of the body 1, thereby improving the safety and speed of carrying the body 1, so that the body 1 can be conveniently carried in the detection site to realize rapid detection of viruses and rapid response to viruses by uploading detection data.
[0024] It should be noted that: the PCR amplifier as prior art, its specific structure and working principle has been mastered by the person skilled in the art, here is not too much.
[0025] Please refer to Figure 2 and Figure 3 The storage assembly in the diagram includes two fixed plates 401 fixedly connected to the side of the connecting block 302 away from the sliding plate 301, a storage rod 402 is arranged between the two fixed plates 401, a storage cloth 403 is wound on the side wall of the storage rod 402, one end of the storage cloth 403 is connected to the storage rod 402, and the other end of the storage cloth 403 is connected to the carrying plate 303. One of the two fixed plates 401 is provided with a winding assembly for winding the storage cloth 403.
[0026] It should be noted here that: through the arrangement of the storage assembly, on the one hand, it provides operation space for the extension of the carrying plate 303, and on the other hand, it provides storage for the carrying plate 303 when not in use to reduce space occupation.
[0027] Please refer to Figure 2 and Figure 3 The winding assembly in the diagram includes a T-shaped winding rod 501 arranged on the side of the fixed plate 401 away from the storage cloth 403, one end of the T-shaped winding rod 501 is connected to the storage rod 402, a torsional spring 502 is sleeved on the side wall of the T-shaped winding rod 501, and the two ends of the torsional spring 502 are respectively connected to the fixed plate 401 and the side wall of the T-shaped winding rod 501.
[0028] It should be noted here that: through the arrangement of the winding assembly, it is convenient to reset and wind the storage cloth 403 after it is pulled out, so as to avoid the entanglement and disorder of the storage cloth 403.
[0029] Working principle: when the machine body 1 needs to be carried, first, the carrying plate 303 on both sides of the base frame 2 is pulled out from the through hole 305, and then the carrying plate 303 is continuously pulled, under the action of the pulling force, the two sliding plates 301 are driven to move away from each other in the base frame 2. When the two fixed plates 401 on the side of the two sliding plates 301 away from each other abut against the inner wall of the base frame 2, the two sliding plates 301 will not move in the base frame 2 under the abutting force. At this time, with the continuous pulling of the two carrying plates 303, the storage cloth 403 wound on the side wall of the storage rod 402 will be pulled out, thereby providing a moving space for the continuous movement of the two carrying plates 303.
[0030] With the continuous pulling of the two carrying plates 303, during the pulling process, the two carrying plates 303 are pulled away from the side of the base frame 2 of the machine body 1 and moved closer to each other, when one side of the two carrying plates 303 abuts the upper side of the machine body 1, the lifting of the machine body 1 can be realized by passing the palm through the hand hole 304 on the two carrying plates 303, so that the staff can realize the carrying of the machine body 1 with one hand, thereby improving the emergency handling of sudden situations during the carrying of the machine body 1 and reducing the risk of falling caused by the simultaneous softness of both hands during the carrying of the machine body 1 through the exchange of left and right hands during the carrying process, thereby improving the safety and speed of carrying the machine body 1;
[0031] When the machine body 1 is carried to the use site, by slowly reducing the pulling force of the two carrying plates 303, under the action of the telescopic assembly and the winding assembly, the two sliding plates 301 are moved closer to each other and the storage cloth 403 is wound to the side wall of the storage rod 402, and then the two carrying plates 303 are stored in the through hole 305, and under the blocking and limiting action of the limiting assembly, the blocking and limiting of the two carrying plates 303 are realized, thereby reducing the space occupation of the carrying assembly. At this time, the machine body 101 can be placed stably and adjusted before detection. After the pre-detection adjustment operation is completed, the sample can be placed in the reaction tube, and the detection mode is started, so that the double-stranded DNA is denatured and unwound into single-stranded DNA at high temperature (usually at a temperature of about 94-98℃), then the primer is specifically combined with the single-stranded DNA template at low temperature (the annealing temperature is different for different primers, generally between 50-65℃), then under the action of DNA polymerase, new DNA double strands are synthesized from single-stranded DNA as a template and dNTP (deoxyribonucleoside triphosphate) as a raw material at a suitable temperature (about 72℃). After one cycle, the number of DNA doubles, and after multiple cycles, the target DNA fragment can be amplified in large quantities. For example, in the process of virus detection, by amplifying the specific gene fragment of the virus, it can be quickly and sensitively judged whether the patient is infected with the virus, and the detection result of the disease is judged after comparing the detection value with the blank correction value of the commonly used disease detection. Then, the Bluetooth communication module of the machine body 1 and the client instruction transmission and data sharing are used, the client uses the network to upload the detection data to the center server in real time, realizes the early warning and detection of the disease, and quickly disposes and reacts, so as to facilitate the machine body 1 to realize the rapid detection of the virus in the detection site and realize the rapid reaction of the virus by uploading the detection data.
[0032] Embodiment 2
[0033] Please refer to Figure 2 and Figure 3The embodiment is further illustrated to the embodiment 1, the limiting assembly in the drawing includes the limiting holes 601 opened in the two inner walls of the through hole 305, the bottom walls of the two limiting holes 601 are connected with the limiting plates 602 through the strong magnetic plates, and the opposite ends of the two limiting plates 602 are connected with the carrying plate 303.
[0034] It should be explained here that: through the setting of the limiting assembly, the limiting of the carrying plate 303 is realized by the magnetic action between the bottom wall strong magnetic plate of the limiting hole 601 and the limiting plate 602, and then the carrying plate 303 is stored and limited when not in use, and the interference to the body 1 in use is avoided.
[0035] Embodiment 3
[0036] Please refer to Figure 2 The embodiment is further illustrated to the other embodiments, the telescopic assembly in the drawing includes the telescopic rods 701 fixedly connected between the two inner walls of the base frame 2, the two sliding plates 301 are slidingly connected to the telescopic rods 701, the side walls of the telescopic rods 701 are sleeved with the two springs 702, and the two ends of the two springs 702 are connected with the inner walls of the base frame 2 and the sliding plates 301 respectively.
[0037] It should be explained here that: through the setting of the telescopic assembly, the reset action is provided for the two sliding plates 301, and the two sliding plates 301 are matched with the inside of the base frame 2, so that the movement of the two sliding plates 301 has a guiding action.
[0038] It should be explained here that: through the setting of the telescopic assembly, the reset action is provided for the two sliding plates 301, and the two sliding plates 301 are matched with the inside of the base frame 2, so that the movement of the two sliding plates 301 has a guiding action.
[0038] It should be explained here that: through the setting of the telescopic assembly, the reset action is provided for the two sliding plates 301, and the two sliding plates 301 are matched with the inside of the base frame 2, so that the movement of the two sliding plates 301 has a guiding action.
[0038] It should be explained here that: through the setting of the telescopic assembly, the reset action is provided for the two sliding plates 301, and the two sliding plates 301 are matched with the inside of the base frame 2, so that the movement of the two sliding plates 301 has a guiding action.
[0038] It should be explained here that: through the setting of the telescopic assembly, the reset action is provided for the two sliding plates 301, and the two sliding plates 301 are matched with the inside of the base frame 2, so that the movement of the two sliding plates 301 has a guiding action.
Claims
1. A portable rapid PCR amplification device, comprising: a body (1); characterized in that it further comprises: a base frame (2) arranged at the bottom of the body (1), the base frame (2) being provided with a carrying assembly facilitating carrying of the body (1); the carrying assembly comprising two sliding plates (301) slidingly connected to the base frame (2), the two sliding plates (301) being fixedly connected with connecting blocks (302) on the sides away from each other, the two connecting blocks (302) being connected with carrying plates (303) on the sides away from the sliding plates (301) through a storage assembly, the two carrying plates (303) being provided with hand holes (304) in the side walls, the base frame (2) being provided with a telescopic assembly for telescoping the two sliding plates (301) and a limiting assembly for limiting the two carrying plates (303).
2. The portable rapid PCR amplification device according to claim 1, wherein: the base frame (2) being provided with through holes (305) in the opposite two side walls, the two sliding plates (301) being slidingly connected to the through holes (305).
3. The portable rapid PCR amplification device according to claim 1, wherein: the storage assembly comprising two fixed plates (401) fixedly connected to the connecting blocks (302) on the sides away from the sliding plates (301), the two fixed plates (401) being provided with a storage rod (402) therebetween, the storage rod (402) being provided with a storage cloth (403) wound on the side wall, one end of the storage cloth (403) being connected with the storage rod (402), the other end of the storage cloth (403) being connected with the carrying plate (303), one of the two fixed plates (401) being provided with a winding assembly for winding the storage cloth (403).
4. The portable rapid PCR amplification device according to claim 3, wherein: the winding assembly comprising a T-shaped winding rod (501) arranged on the side of the fixed plate (401) away from the storage cloth (403), one end of the T-shaped winding rod (501) being connected with the storage rod (402), the side wall of the T-shaped winding rod (501) being provided with a torsional spring (502), the two ends of the torsional spring (502) being connected with the side wall of the fixed plate (401) and the T-shaped winding rod (501) respectively.
5. The portable rapid PCR amplification device according to claim 4, wherein: the limiting assembly comprising limiting holes (601) arranged in the opposite two inner walls of the through holes (305), the two limiting holes (601) being connected with limiting plates (602) through strong magnetic plates on the bottom walls, the opposite ends of the two limiting plates (602) being connected with the carrying plates (303).
6. The portable rapid PCR amplification device according to claim 5, wherein: the telescopic assembly comprising a telescopic rod (701) fixedly connected between the opposite two inner walls of the base frame (2), the two sliding plates (301) being slidingly connected to the telescopic rod (701), the side wall of the telescopic rod (701) being provided with two springs (702), the two ends of the two springs (702) being connected with the inner walls of the base frame (2) and the sliding plates (301) respectively.