Biological cell dyeing device

By designing an adjustment tilting mechanism and a waste liquid collection mechanism for the biological cell staining device, the problem of slow staining agent flow was solved, and efficient staining of large-area cells was achieved.

CN223742119UActive Publication Date: 2025-12-30SHENZHEN LANGJINWEIZI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202423313398.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-31
Publication Date
2025-12-30
Estimated Expiration
2034-12-31

AI Technical Summary

Technical Problem

In existing biological cell staining devices, the staining agent has a slow flow rate, resulting in low efficiency when staining large areas of cells.

Method used

A biological cell staining device was designed, comprising an adjustment tilting mechanism, a clamping mechanism, and a waste liquid collection mechanism. The device accelerates the flow rate of the staining agent by tilting the support plate and collects excess staining agent, thereby improving staining efficiency.

Benefits of technology

By tilting the support plate to accelerate the flow of staining agent, the efficiency of large-area cell staining is improved, avoiding the reduction in work efficiency caused by slow staining agent flow.

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Abstract

The utility model belongs to the field of biological cell dyeing, and particularly relates to a biological cell dyeing device which comprises a cell dyeing device body, and the cell dyeing device body comprises an operation table; according to the cell staining device, the cell staining device body, the inclination adjusting mechanism, the clamping mechanism and the waste liquid collecting mechanism are matched for use, a cell placement piece can be clamped by the clamping mechanism, then a staining agent is dropped into the cell placement piece by the staining device body, and then the angle of the supporting disc is adjusted by adjusting the inclination mechanism; the flowing speed of a coloring agent is increased through the inclined supporting disc, the cells are dyed, meanwhile, the redundant coloring agent flows into the inner cavity of the collecting tank and is finally collected by the waste liquid collecting mechanism, and the situation that the flowing speed of the coloring agent is generally low, and if a large-area cell is wanted to be dyed, the cell cannot be dyed is avoided. The slow flowability of the staining agent can influence the cell staining speed, and the working efficiency is reduced.
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Description

Technical Field

[0001] This utility model relates to the field of biological cell staining, specifically a biological cell staining device. Background Technology

[0002] Cell staining is a commonly used experimental technique in biology. By treating cells, its internal structure or certain components are made to show color, thereby helping researchers observe and study cell structure and function. The development of cell staining technology has provided important tools and methods for cell biology and medical research. Cell staining devices are used in cell staining work.

[0003] In the process of staining biological cells, a cell staining device is used. However, a typical staining device involves dripping the staining agent onto the fixed biological cells, allowing the staining agent to slowly cover all the cells through its own fluidity. But usually, the fluidity of the staining agent is relatively slow. If you want to stain a large area of ​​cells, the slow fluidity of the staining agent will affect the cell staining speed and reduce work efficiency. Utility Model Content

[0004] To address the shortcomings of existing technologies, which typically involve slow-flowing staining agents, the slow flow of the staining agent can affect the staining speed and reduce work efficiency when staining large areas of cells. This invention proposes a biological cell staining device.

[0005] The technical solution adopted by this utility model to solve its technical problem is: a biological cell staining device, including a cell staining device body, the cell staining device body including an operating table, the bottom of the operating table is fixedly connected to a support leg, the number of the support leg is four, the top of the operating table is fixedly connected to a back plate, one side of the back plate is fixedly connected to a top plate, the top of the top plate is fixedly connected to a storage tank, the bottom of the top plate is fixedly connected to a dye pump, the input end of the dye pump passes through the inner cavity of the top plate and is fixedly connected to the inner cavity of the storage tank, the output end of the dye pump is fixedly connected to a dropper, the top of the operating table is provided with an adjustment tilting mechanism, the top of the adjustment tilting mechanism is provided with a clamping mechanism, and the top of the operating table is provided with a waste liquid collection mechanism;

[0006] The tilt adjustment mechanism includes a support plate, the bottom of which is fixedly connected to the top of the operating table. Three motors are fixedly connected to the top of the support plate. Each motor's output end has a first gear fixedly connected to its surface, and the height of each first gear is different. A support column is fixedly connected to the top of the support plate. A rotating column is movably connected to the inner cavity of the support column. A first sleeve column is movably connected to the surface of the rotating column. A second sleeve column is movably connected to the surface of the first sleeve column. Second gears are fixedly connected to the surfaces of the rotating column, the first sleeve column, and the second sleeve column. The teeth of each second gear mesh with the teeth of one of the first gears. A connecting rod is fixedly connected to the surface of each of the rotating column, the first sleeve column, and the second sleeve column. A first support rod is fixedly connected to the surface of the connecting rod. A linkage rod is movably connected to the surface of the first support rod. A second support rod is movably connected to the inner cavity of the linkage rod. A support plate is fixedly connected to the surfaces of the three second support rods.

[0007] Preferably, the surfaces of the first support rod and the second support rod are both fixedly connected to limit rings, and the surfaces of the limit rings are movably connected to the surfaces of the linkage rods.

[0008] Preferably, the clamping mechanism includes two fixing blocks. The bottom of each fixing block is fixedly connected to the top of the support plate. The inner cavities of the two fixing blocks are movably connected to a bidirectional screw. A rotating handle is fixedly connected to the surface of the bidirectional screw. Two moving blocks are threadedly connected to the surface of the bidirectional screw. The bottom of each moving block is movably connected to the top of the support plate.

[0009] Preferably, a bearing is fixedly connected to the surface of the bidirectional screw, and the outer ring of the bearing is fixedly connected to the surface of one of the fixing blocks.

[0010] Preferably, the inner cavity of the support plate is provided with a dovetail groove, and a dovetail block is movably connected to the inner cavity of the dovetail groove. There are two dovetail blocks, and the top of each dovetail block is fixedly connected to the bottom of a movable block.

[0011] Preferably, the waste liquid collection mechanism includes a collection pipe, one end of which is fixedly connected to the bottom of the support plate, and the other end of which is fixedly connected to a collection tank. The bottom of the collection tank is fixedly connected to the top of the operating table, and the bottom of the operating table is fixedly connected to an outlet pipe, one end of which is fixedly connected to the bottom of the collection tank.

[0012] Preferably, the inner cavity of the support plate is provided with a collection groove, and the inner cavity of the collection groove is connected to one end of the collection tube.

[0013] The advantages of this utility model are:

[0014] This invention utilizes a combination of a cell staining device body, an adjusting tilting mechanism, a clamping mechanism, and a waste liquid collection mechanism. The clamping mechanism holds the cell placement slide, and the staining device body drips staining agent onto the slide. The tilting mechanism then adjusts the angle of the support plate, accelerating the flow of staining agent through the tilted plate to stain the cells. Excess staining agent flows into the collection tank and is collected by the waste liquid collection mechanism. This design avoids the problem of slow staining agent flow, which can hinder staining speed and reduce efficiency when staining large areas of cells. Attached Figure Description

[0015] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is a schematic diagram of the main body structure of this utility model;

[0017] Figure 2 This is a schematic diagram of the support plate structure of this utility model;

[0018] Figure 3 This is a schematic diagram of the cross-sectional structure of the support column of this utility model;

[0019] Figure 4 This is a schematic diagram of the support plate structure of this utility model.

[0020] In the diagram: 1. Cell staining apparatus body; 101. Operating table; 102. Support leg; 103. Dropper; 104. Back plate; 105. Storage tank; 106. Dye pump; 107. Top plate; 2. Adjustment tilting mechanism; 201. Support plate; 202. Motor; 203. First gear; 204. Connecting rod; 205. First support rod; 206. Support column; 207. Rotating column; 208. Linkage rod; 209. Second gear; 210. Limiting ring; 211. Second support rod; 212. First connecting post; 213. Second connecting post; 214. Support plate; 3. Clamping mechanism; 301. Fixing block; 302. Bearing; 303. Dovetail block; 304. Rotating handle; 305. Moving block; 306. Bidirectional screw; 307. Dovetail groove; 4. Waste liquid collection mechanism; 401. Collection pipe; 402. Collection tank; 403. Collection trough; 404. Outlet pipe. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present utility model.

[0022] The following is in conjunction with the appendix Figure 1-4 This application will be described in further detail.

[0023] This application discloses a biological cell staining device. (Refer to...) Figure 1 and Figure 4 A biological cell staining device includes a cell staining device body 1, which includes an operating table 101. Four support legs 102 are fixedly connected to the bottom of the operating table 101. A back plate 104 is fixedly connected to the top of the operating table 101. A top plate 107 is fixedly connected to one side of the back plate 104. A storage tank 105 is fixedly connected to the top of the top plate 107. A dye pump 106 is fixedly connected to the bottom of the top plate 107. The input end of the dye pump 106 passes through the inner cavity of the top plate 107 and is fixedly connected to the inner cavity of the storage tank 105. A dropper 103 is fixedly connected to the output end of the dye pump 106. An adjustment tilting mechanism 2 is provided on the top of the operating table 101. A clamping mechanism 3 is provided on the top of the adjustment tilting mechanism 2. A waste liquid collection mechanism 4 is provided on the top of the operating table 101.

[0024] The tilting adjustment mechanism 2 includes a support plate 201. The bottom of the support plate 201 is fixedly connected to the top of the operating table 101. Three motors 202 are fixedly connected to the top of the support plate 201. Each motor 202 has a first gear 203 fixedly connected to its output end. The height of each first gear 203 is different. A support column 206 is fixedly connected to the top of the support plate 201. A rotating column 207 is movably connected to the inner cavity of the support column 206. A first connecting column 212 is movably connected to the surface of the rotating column 207. A second connecting column 213 is movably connected to the surface of the first connecting column 212. The surfaces of the rotating column 207, the first connecting column 212, and the second connecting column 213 are all fixedly connected to the second gear 209. The teeth of each second gear 209 mesh with the teeth of a first gear 203. The surfaces of the rotating column 207, the first connecting column 212, and the second connecting column 213 are all fixedly connected to a connecting rod 204. The surface of the connecting rod 204 is fixedly connected to a first support rod 205. The surface of the first support rod 205 is movably connected to a linkage rod 208. The inner cavity of the linkage rod 208 is movably connected to a second support rod 211. The surfaces of the three second support rods 211 are all fixedly connected to a support disk 214.

[0025] Reference Figure 2 Limiting rings 210 are fixedly connected to the surfaces of the first support rod 205 and the second support rod 211. The surface of the limiting ring 210 is movably connected to the surface of the linkage rod 208. The limiting ring 210 limits the linkage rod 208 so that the linkage rod 208 will not detach from the surfaces of the first support rod 205 and the second support rod 211 when the surfaces rotate.

[0026] Reference Figure 2 and Figure 4 The clamping mechanism 3 includes two fixed blocks 301. The bottom of the fixed blocks 301 is fixedly connected to the top of the support plate 214. The inner cavities of the two fixed blocks 301 are movably connected to a bidirectional screw 306. A rotating handle 304 is fixedly connected to the surface of the bidirectional screw 306. A moving block 305 is threadedly connected to the surface of the bidirectional screw 306. There are two moving blocks 305. The bottom of the moving block 305 is movably connected to the top of the support plate 214. By setting the fixed blocks 301, rotating handle 304, moving blocks 305 and bidirectional screw 306 to work together, the bidirectional screw 306 can be rotated when the rotating handle 304 is rotated, so that the moving blocks 305 can move inward or outward simultaneously while being threadedly connected to the surface of the bidirectional screw 306.

[0027] Reference Figure 2A bearing 302 is fixedly connected to the surface of the bidirectional screw 306. The outer ring of the bearing 302 is fixedly connected to the surface of one of the fixing blocks 301. By setting the bearing 302, the rotation position of the bidirectional screw 306 can be limited without affecting the rotation of the bidirectional screw 306, so that the bidirectional screw 306 will not detach from the inner cavity of the fixing block 301 during rotation.

[0028] Reference Figure 4 The inner cavity of the support plate 214 is provided with a dovetail groove 307. A dovetail block 303 is movably connected to the inner cavity of the dovetail groove 307. There are two dovetail blocks 303. The top of each dovetail block 303 is fixedly connected to the bottom of a moving block 305. By setting the dovetail blocks 303 and the dovetail groove 307 to work together, the moving block 305 is guided when it slides on the surface of the support plate 214. At the same time, the moving block 305 is also limited, so that when the bidirectional screw 306 rotates, it will not drive the moving block 305 to rotate. Instead, the moving block 305 moves on the surface of the support plate 214 through the threaded connection with the bidirectional screw 306.

[0029] Reference Figure 1 and Figure 2 The waste liquid collection mechanism 4 includes a collection pipe 401. One end of the collection pipe 401 is fixedly connected to the bottom of the support plate 214, and the other end of the collection pipe 401 is fixedly connected to a collection tank 402. The bottom of the collection tank 402 is fixedly connected to the top of the operating table 101, and the bottom of the operating table 101 is fixedly connected to an outlet pipe 404. One end of the outlet pipe 404 is fixedly connected to the bottom of the collection tank 402. By setting the collection pipe 401, the collection tank 402 and the outlet pipe 404 to work together, excess dyeing agent can be collected and input into the inner cavity of the collection tank 402 through the collection pipe 401. Finally, the outlet pipe 404 can be opened to allow the waste dyeing agent in the inner cavity of the collection tank 402 to flow out by gravity.

[0030] Reference Figure 2 and Figure 4 The inner cavity of the support plate 214 is provided with a collection groove 403. The inner cavity of the collection groove 403 is connected to one end of the collection tube 401. Through the collection groove 403, excess dye on the surface of the support plate 214 can be collected when the support plate 214 is tilted, and then guided to the connection between the collection tube 401 and the support plate 214, and finally flow into the interior of the collection tube 401.

[0031] Working principle: First, the cell placement slide is placed between two moving blocks 305. Then, the handle 304 is turned, which drives the bidirectional screw 306 to rotate. The threaded connection between the bidirectional screw 306 and the inner cavity of the moving blocks 305 causes the two moving blocks 305 to move inward until the cell placement slide is clamped. Then, the dye pump 106 starts working, drawing dye from the storage tank 105 through the input end of the dye pump 106, and then delivering the dye to the dropper 103 through the output end of the dye pump 106. Finally, the dye is dripped onto the cell placement slide through the dropper 103. Then, the three motors... Starting from 202, the motor rotates in both directions sequentially. The output of motor 202 drives the first gear 203 to rotate, which in turn drives one of the second gears 209. Since a second gear 209 is fixedly connected to each of the rotating column 207, the first connecting column 212, and the second connecting column 213, and the positional relationship of the rotating column 207, the first connecting column 212, and the second connecting column 213 is as follows: the rotating column 207 rotates within the cavity of the support column 206, the first connecting column 212 rotates on the surface of the rotating column 207, and the second connecting column 213 rotates on the surface of the first connecting column 212. Therefore, in one of the... When the motor 202 indirectly drives the second gear 209 to rotate, the second gear 209 will drive the rotating column 207, the first connecting column 212, and the second connecting column 213 to rotate respectively. The rotating column 207, the first connecting column 212, and the second connecting column 213 will each drive a connecting rod 204 to rotate. The connecting rod 204 drives the first support rod 205 to move, which in turn drives the linkage rod 208 to rotate. The linkage rod 208 then drives the second support rod 211 to move, which in turn causes the support plate 214 to tilt in one direction. Because of the three... Motor 202 operates sequentially, and after completing the tilt, it rotates in the opposite direction to return to its original position. Therefore, the support plate 214 can be tilted in three directions and returned to its original position sequentially. The inclined surface accelerates the flow rate of the staining agent, thereby increasing the efficiency of cell coverage. At the same time, the tilting allows excess staining agent to flow into the inner cavity of the collection tank 403, then into the inside of the collection tube 401, and finally into the inner cavity of the collection container 402. When it is necessary to process the waste staining agent in the inner cavity of the collection container 402, the outlet tube 404 is opened. Due to gravity, the waste staining agent in the collection container 402 will flow out through the outlet tube 404.

[0032] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model.

Claims

1. A biological cell staining device comprising a cell staining device body (1), characterized in that: The cell staining device body (1) includes an operating table (101), the bottom of the operating table (101) is fixedly connected with support legs (102), the number of the support legs (102) is four, the top of the operating table (101) is fixedly connected with a back plate (104), one side of the back plate (104) is fixedly connected with a top plate (107), the top of the top plate (107) is fixedly connected with a storage tank (105), the bottom of the top plate (107) is fixedly connected with a dye pump (106), the input end of the dye pump (106) penetrates the inner cavity of the top plate (107) and is fixedly communicated with the inner cavity of the storage tank (105), the output end of the dye pump (106) is fixedly communicated with a dropper (103), the top of the operating table (101) is provided with an adjusting inclination mechanism (2), the top of the adjusting inclination mechanism (2) is provided with a clamping mechanism (3), and the top of the operating table (101) is provided with a waste liquid collecting mechanism (4). The adjusting inclination mechanism (2) includes a support plate (201), the bottom of the support plate (201) is fixedly connected with the top of the operating table (101), the top of the support plate (201) is fixedly connected with motors (202), the number of the motors (202) is three, the surface of the output end of each motor (202) is fixedly connected with a first gear (203), the height of each first gear (203) is different, the top of the support plate (201) is fixedly connected with a support column (206), the inner cavity of the support column (206) is movably connected with a rotating column (207), the surface of the rotating column (207) is movably connected with a first sleeve column (212), the surface of the first sleeve column (212) is movably connected with a second sleeve column (213), the surfaces of the rotating column (207), the first sleeve column (212) and the second sleeve column (213) are fixedly connected with second gears (209), the teeth of each second gear (209) are meshingly connected with the teeth of a first gear (203), the surfaces of the rotating column (207), the first sleeve column (212) and the second sleeve column (213) are fixedly connected with a connecting rod (204), the surface of the connecting rod (204) is fixedly connected with a first support rod (205), the surface of the first support rod (205) is movably connected with a linkage rod (208), the inner cavity of the linkage rod (208) is movably connected with a second support rod (211), and the surfaces of the three second support rods (211) are fixedly connected with a support disc (214).

2. The biological cell staining device according to claim 1, wherein: The surfaces of the first support rod (205) and the second support rod (211) are fixedly connected with limit rings (210), and the surfaces of the limit rings (210) are movably connected with the surface of the linkage rod (208).

3. The biological cell staining device according to claim 1, wherein: The clamping mechanism (3) includes fixed blocks (301), the number of the fixed blocks (301) is two, the bottom of the fixed block (301) is fixedly connected with the top of the support disc (214), the inner cavities of the two fixed blocks (301) are movably connected with a bidirectional screw rod (306), the surface of the bidirectional screw rod (306) is fixedly connected with a rotating handle (304), the surface of the bidirectional screw rod (306) is threadedly connected with a moving block (305), the number of the moving block (305) is two, and the bottom of the moving block (305) is movably connected with the top of the support disc (214).

4. The biological cell staining device according to claim 3, wherein: The surface of the bidirectional screw rod (306) is fixedly connected with a bearing (302), and the outer ring of the bearing (302) is fixedly connected with the surface of one of the fixed blocks (301).

5. The biological cell staining device according to claim 3, wherein: The inner cavity of the support disc (214) is provided with dovetail grooves (307), the inner cavities of the dovetail grooves (307) are movably connected with dovetail blocks (303), the number of the dovetail blocks (303) is two, and the top of each dovetail block (303) is fixedly connected with the bottom of one moving block (305).

6. The biological cell staining device of claim 1, wherein: The waste liquid collecting mechanism (4) includes a collecting pipe (401), one end of the collecting pipe (401) is fixedly communicated with the bottom of the support disc (214), the other end of the collecting pipe (401) is fixedly communicated with a collecting tank (402), the bottom of the collecting tank (402) is fixedly connected with the top of the operation table (101), the bottom of the operation table (101) is fixedly connected with a leading-out pipe (404), one end of the leading-out pipe (404) is fixedly communicated with the inner cavity of the collecting tank (402).

7. The biological cell staining device of claim 1, wherein: The inner cavity of the support disc (214) is provided with a collecting groove (403), and the inner cavity of the collecting groove (403) is communicated with one end of the collecting pipe (401).