Nucleic acid extractor movement mechanism and nucleic acid extractor

By designing the lifting frame and drive components of the motion mechanism of the nucleic acid extractor, the problem of synchronous movement between the magnetic rod and the magnetic rod sleeve was solved, achieving higher synchronization and stability, and improving the purity and quality of nucleic acid extraction.

CN223752729UActive Publication Date: 2026-01-02SIKUN LIFE SCIENCE CO LTD
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Patent Information

Application Number
CN202422910823.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-11-27
Publication Date
2026-01-02
Estimated Expiration
2034-11-27

AI Technical Summary

Technical Problem

In existing technologies, deviations can easily occur between the magnetic rod and the magnetic rod sleeve during movement, resulting in gaps that affect the firmness of magnetic bead adsorption and reduce the purity and quality of nucleic acid extraction.

Method used

The motion mechanism of the nucleic acid extractor includes a mounting bracket, a horizontal motion component, a vertical motion component, and a displacement component. Through the cooperation of the lifting frame and the drive component, the magnetic rod assembly and the magnetic rod sleeve assembly are moved synchronously, avoiding movement gaps and improving synchronization.

Benefits of technology

This improved the consistency of movement between the magnetic rod and the magnetic rod sleeve, ensuring stable magnetic bead adsorption and enhancing the purity and quality of nucleic acid extraction.

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Abstract

The utility model provides a nucleic acid extractor movement mechanism and a nucleic acid extractor.The nucleic acid extractor movement mechanism comprises a mounting bracket, a first rotating shaft, a second rotating shaft and a third rotating shaft, and the mounting bracket is fixed relative to a box body of the nucleic acid extractor; the transverse movement mechanism is provided with a mounting position which moves in the transverse direction relative to the mounting bracket; the longitudinal movement mechanism comprises a lifting frame and a longitudinal driving part, the lifting frame is connected to the mounting position in a sliding mode, the longitudinal driving part is arranged on the mounting position, and the longitudinal driving mechanism is used for driving the lifting frame to slide; the shifting assembly comprises a shifting base body arranged on the lifting frame and a shifting drive arranged on the lifting frame, and the shifting drive drives the shifting base body to slide relative to the lifting frame; wherein the lifting frame is used for installing a magnetic bar sleeve assembly, and the displacement base body is used for installing a magnetic bar assembly. By adopting the technical scheme, the stability of synchronous movement of the magnetic rod assembly and the magnetic rod sleeve assembly is improved, the relative displacement deviation is reduced, and the nucleic acid extraction quality is improved.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of gene detection, and particularly relates to a nucleic acid extractor movement mechanism and a nucleic acid extractor. BACKGROUND

[0002] In a nucleic acid extraction process, a nucleic acid extractor is used to extract and process samples, and the most widely used method is magnetic bead extraction. Through the movement mechanism of the nucleic acid extractor, magnetic beads are used to assist in adsorption, and samples are moved between different positions to perform different functions, so as to realize steps such as lysis, combination, washing, and elution of nucleic acid samples.

[0003] In the above steps, mixing and magnetic adsorption processes need to be performed. Mixing requires that the magnetic rod sleeve and the magnetic rod are separated, and the magnetic rod sleeve moves alone to mix the nucleic acid and the magnetic beads. In the magnetic adsorption process, the magnetic rod is inserted into the magnetic rod sleeve, and the combination of the magnetic beads and the nucleic acid is adsorbed on the surface of the magnetic rod sleeve. The corresponding driving mechanisms of the magnetic rod and the magnetic rod sleeve drive the two to move synchronously, and the combination of the magnetic beads and the nucleic acid is transferred to the subsequent washing and elution holes. In the magnetic adsorption process, the magnetic rod and the magnetic rod sleeve need to keep moving synchronously to ensure stable adsorption of the magnetic beads. However, in the prior art, there may be a deviation in the displacement process of the driving mechanisms of the magnetic rod and the magnetic rod sleeve, which may cause a movement gap between the magnetic rod and the magnetic rod sleeve. The movement gap may cause the magnetic beads to be adsorbed unstably, and the purity and quality of the extraction may be reduced. CONTENT

[0004] The present application provides a nucleic acid extractor movement mechanism and a nucleic acid extractor, which can avoid the generation of a movement gap between the magnetic rod assembly and the magnetic rod sleeve assembly, improve the consistency of the movement of the two, and improve the quality of nucleic acid extraction.

[0005] In a first aspect, the present application provides a nucleic acid extractor movement mechanism, which comprises

[0006] A mounting bracket is fixed relative to a box body of the nucleic acid extractor;

[0007] A transverse movement mechanism is provided with a mounting position for transverse displacement relative to the mounting bracket;

[0008] A longitudinal movement mechanism comprises a lifting frame slidingly connected to the mounting position and a longitudinal driving member arranged on the mounting position, and the longitudinal driving mechanism is used to drive the lifting frame to slide;

[0009] A displacement assembly comprises a displacement base arranged on the lifting frame and a displacement drive arranged on the lifting frame, and the displacement drive drives the displacement base to slide relative to the lifting frame;

[0010] The lifting frame is used for mounting the magnetic rod sleeve assembly, and the displacement base is used for mounting the magnetic rod assembly.

[0011] In a specific implementation, the displacement driving member comprises a displacement motor fixed on the lifting frame and a driving screw rotatably connected to the lifting frame.

[0012] The driving screw is threadedly connected to the magnetic rod assembly or the displacement base.

[0013] The output end of the displacement motor is connected to the displacement driving screw to drive the driving screw to rotate.

[0014] In a specific implementation, the lifting frame is fixedly connected with a mounting base, and the displacement motor is fixedly connected to the mounting base.

[0015] One end of the driving screw is rotatably connected to the magnetic rod sleeve assembly, and the other end is rotatably connected to the mounting base.

[0016] In a specific implementation, the mounting position is fixedly connected with a sliding rail.

[0017] The lifting frame is fixedly connected with a sliding block, and the sliding block is slidably connected to the sliding rail.

[0018] The displacement base is also fixedly connected with a sliding block, and the lifting frame is provided with a clearance hole, and the sliding block on the displacement base is slidably connected to the sliding rail through the clearance hole.

[0019] In a specific implementation, the transverse movement assembly comprises a transverse moving frame slidably connected to the mounting support and a transverse driving member for driving the transverse moving frame to move.

[0020] The mounting position is located on the transverse moving frame.

[0021] The longitudinal driving member comprises at least two transmission wheels rotatably connected to the transverse moving frame, a transmission belt tautly arranged between the transmission wheels, and a longitudinal driving motor fixedly connected to the transverse moving frame, wherein the longitudinal driving motor is connected to the transmission wheels to drive the transmission wheels to rotate.

[0022] The lifting frame is fixedly connected to one side of the transmission belt.

[0023] In a specific implementation, a tensioning adjusting assembly is further included, which is connected to the transmission wheels to adjust the distance between the two transmission wheels at the two ends of the transmission belt.

[0024] In one specific implementation, the tension adjustment assembly includes a fixed block fixed on the horizontal moving frame, a tension block slidingly connected to the horizontal moving frame, and an adjustment screw;

[0025] The fixed block and the tension block are locked at a set distance apart by the adjustment screw;

[0026] One of the transmission wheels located at one end of the transmission belt is rotatably connected to the tension block.

[0027] In one specific implementation, the horizontal driving member includes a sliding block fixedly connected to the horizontal moving frame, a horizontal driving motor fixedly connected to the mounting bracket, and a driving rod rotatably connected to the mounting bracket;

[0028] The driving rod passes through the sliding block and is threadedly engaged with the sliding block;

[0029] The horizontal driving motor is connected to the driving rod to drive the driving rod to rotate.

[0030] In one specific implementation, the mounting bracket is further fixedly connected with a sliding rail;

[0031] The horizontal moving frame is fixedly connected with a sliding block, and the sliding block is slidingly engaged with the sliding rail.

[0032] In a second aspect, the present application further provides a nucleic acid extractor, which comprises the nucleic acid extractor movement mechanism according to any one of the above. BRIEF DESCRIPTION OF DRAWINGS

[0033] Figure 1 A schematic view of the nucleic acid extractor movement mechanism provided by the embodiment of the present application connected with a magnetic rod assembly and a magnetic rod sleeve assembly;

[0034] Figure 2 A schematic view of the overall structure of the nucleic acid extractor movement mechanism provided by the embodiment of the present application;

[0035] Figure 3 A schematic view of the longitudinal movement assembly and the displacement assembly provided by the embodiment of the present application;

[0036] Figure 4 A schematic view showing the structure of the horizontal movement assembly provided by the embodiment of the present application;

[0037] Figure 5 A schematic view of the nucleic acid extractor movement mechanism provided by the embodiment of the present application; Figure 1 An enlarged schematic view of part A. DETAILED DESCRIPTION

[0038] In order to make the purposes, technical solutions and advantages of the present application clearer, the present application will be further described in detail below with reference to the drawings.

[0039] It should be noted that, unless otherwise defined, technical terms or scientific terms used in one or more embodiments of the present application shall have the usual meaning understood by a person skilled in the art to which the present disclosure belongs. The terms "first", "second" and the like used in one or more embodiments of the present application do not represent any order, number or importance, but are only used to distinguish different components. The terms "include" or "contain" and the like mean that the elements or objects before the terms cover the elements or objects listed after the terms and their equivalents, and do not exclude other elements or objects. The terms "connect" or "connected" and the like are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. The terms "up", "down", "left", "right" and the like are only used to represent relative positional relationships, and when the absolute positions of the described objects change, the relative positional relationships may also change accordingly.

[0040] In order to facilitate the understanding of the nucleic acid extractor motion mechanism and the nucleic acid extractor provided by the embodiments of the present application, the application scenarios thereof are first described. The nucleic acid extractor is applied in the nucleic acid extraction process to extract and process nucleic acid samples. At present, the most widely used method is magnetic bead extraction. The motion mechanism of the nucleic acid extractor assists the use of magnetic beads adsorption to carry the samples to move in different positions to perform different functions, so as to realize the steps of lysis, combination, washing and elution of the nucleic acid samples.

[0041] In the above steps, mixing, magnetic adsorption and other processes need to be performed. Mixing requires that the magnetic rod sleeve and the magnetic rod are separated, and the magnetic rod sleeve moves alone to mix the nucleic acid and the magnetic beads. Magnetic adsorption (i.e., the stage of keeping the combination of the magnetic beads and the nucleic acid adsorbed on the surface of the magnetic rod sleeve) is to insert the magnetic rod into the magnetic rod sleeve to keep the combination of the magnetic beads and the nucleic acid adsorbed on the surface of the magnetic rod sleeve. The corresponding driving mechanisms of the magnetic rod and the magnetic rod sleeve drive the two to move synchronously, so as to transfer the combination of the magnetic beads and the nucleic acid to the subsequent washing and elution holes. During the magnetic adsorption process, the magnetic rod and the magnetic rod sleeve need to keep the actions synchronized to ensure stable adsorption of the magnetic beads.

[0042] Since the magnetic rod and the magnetic rod sleeve of the prior art are driven by the corresponding driving mechanisms respectively during movement, they need to be moved relatively, and in this case, one of them, for example, the magnetic rod, can be directly driven to displace to realize actions such as insertion into and extraction from the magnetic rod sleeve. When both need to displace synchronously, for example, during magnetic attraction, the magnetic rod and the magnetic rod sleeve need to move synchronously, and two control programs are needed to control the actions of the two corresponding driving mechanisms respectively, and it is difficult to ensure that the two driving mechanisms are completely synchronous, and a mechanism with higher precision also needs higher cost.

[0043] Thus, during nucleic acid extraction, displacement deviation may occur between the magnetic rod and the magnetic rod sleeve, resulting in a movement gap therebetween, especially during magnetic attraction, which requires higher synchronous matching precision; the movement gap may cause the magnetic beads to be adsorbed insecurely, directly affecting the mixing quality and causing the problems of decreased extraction purity and quality.

[0044] Therefore, the embodiments of the present application provide a nucleic acid extractor movement mechanism and a nucleic acid extractor to avoid the problem of movement gap between the magnetic rod and the magnetic rod sleeve during movement, ensure the quality of the nucleic acid extraction process, and help improve the extraction purity. The following will be described in detail in combination with specific drawings and embodiments.

[0045] First of all, it should be pointed out that the nucleic acid extractor movement mechanism is part of the nucleic acid extractor, which includes a box body, a placement table arranged in the box body for placing consumables, a magnetic rod assembly, a magnetic rod sleeve assembly, and a movement mechanism. The movement mechanism drives the magnetic rod assembly and the magnetic rod sleeve assembly to displace, and in combination with the arranged magnetic beads, drives the nucleic acid sample to transfer between different consumable hole positions and adjacent processing components to perform steps such as lysis, combination, washing, and elution.

[0046] First of all, refer to Figure 1 The nucleic acid extractor movement mechanism provided by the embodiments of the present application is used to install the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2 and drive the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2 to displace horizontally and vertically. The magnetic rod assembly 1 and the magnetic rod sleeve assembly 2 are both structures commonly used in the field of nucleic acid extraction process, and this part will not be described in detail in the embodiments of the present application.

[0047] Refer to Figure 2 and Figure 3The nucleic acid extractor movement mechanism comprises a mounting bracket 3, a transverse movement assembly 4, a longitudinal movement assembly 5 and a displacement assembly 6, wherein the mounting bracket 3 is fixedly connected with a box body of the nucleic acid extractor as a mounting basis of the movement mechanism; the transverse movement assembly 4 is arranged on the mounting bracket 3 and is provided with a mounting position for transverse displacement relative to the mounting bracket 3; the longitudinal movement assembly 5 is arranged on the mounting position and is driven by the transverse movement assembly 4 to displace relative to the mounting bracket 3 along the transverse direction.

[0048] The longitudinal movement assembly 5 comprises a lifting frame 51 slidably connected to the mounting position and a longitudinal driving member 52 fixedly connected to the mounting position, wherein the longitudinal driving member 52 is connected with the lifting frame 51 to drive the lifting frame 51 to slide relative to the transverse movement assembly 4 along the longitudinal direction to realize lifting.

[0049] The displacement assembly 6 comprises a displacement base body 61 arranged on the lifting frame 51 and a displacement driving member 62 arranged on the lifting frame 51, wherein the displacement driving member 62 moves synchronously with the lifting frame 51, and the displacement driving member 62 is connected with the displacement base body 61 to drive the displacement base body 61 to slide relative to the lifting frame 51.

[0050] The magnetic rod assembly 1 is fixedly connected to the displacement base body 61, and correspondingly, the displacement driving member 62 can be connected with the displacement base body 61 or the magnetic rod assembly 1, as long as it can drive the magnetic rod assembly 1 to move relative to the lifting frame 51. The magnetic rod sleeve assembly 2 is fixedly connected to the lifting frame 51. For example, a fixed base body 53 is fixedly connected to the lifting frame 51, and the magnetic rod sleeve assembly 2 is fixedly connected to the fixed base body 53. In other embodiments, the magnetic rod sleeve assembly 2 can be directly fixedly connected to the lifting frame 51.

[0051] During the nucleic acid extraction process, the consumables are located at the working position for extraction and are fixed. The transverse movement assembly 4 drives the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2 to move transversely, the longitudinal movement assembly 5 drives the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2 to move longitudinally, and the displacement assembly 6 drives the magnetic rod assembly 1 to move alone, so as to realize the movement of the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2 in the plane.

[0052] The displacement driving member 62 drives the magnetic rod assembly 1 to slide relative to the lifting frame 51, and the magnetic rod sleeve assembly 2 is fixedly connected to the lifting frame 51 through the fixed base body 53, so as to drive the magnetic rod assembly 1 to move relative to the magnetic rod sleeve assembly 2, realize the insertion of the magnetic rod into the magnetic rod sleeve and the extraction of the magnetic rod from the magnetic rod sleeve.

[0053] The longitudinal driving member 52 drives the lifting frame 51 to slide, and the displacement driving member 62 remains in a stationary state, that is, the magnetic rod assembly 1 is stationary relative to the displacement driving member 62, that is, stationary relative to the lifting frame 51. In this way, by driving the longitudinal driving member 52, the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2 can be driven to move synchronously. When performing magnetic attraction, it is not necessary to separately control the movement of the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2. It is only necessary to control the displacement driving member 62 to remain in a stationary state and control the longitudinal driving member 52 to drive. This greatly reduces the difficulty of regulation and control, reduces the requirement for the regulation and control accuracy of the drive, reduces the problem of movement gap between the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2, and improves the quality of nucleic acid extraction.

[0054] With reference to Figure 2 and Figure 4 , the transverse movement assembly 4 comprises a transverse sliding frame 41 slidably connected to the mounting bracket 3 and a transverse driving member 42. The transverse driving member 42 is connected to the mounting bracket 3 and the transverse sliding frame 41 and is used to drive the transverse sliding frame 41 to slide relative to the mounting bracket 3. The installation position is located on the transverse sliding frame 41.

[0055] The transverse driving member 42 comprises a sliding block 421 fixedly connected to the transverse sliding frame 41, a transverse driving motor 422 fixedly connected to the mounting bracket 3, and a driving rod 423 rotatably connected to the mounting bracket 3. The driving rod 423 penetrates through the sliding block 421 and is threadedly connected to the sliding block 421. The output end of the transverse driving motor 422 is connected to the driving rod 423 to drive the driving rod 423 to rotate. The transverse driving motor 422 drives the driving rod 423 to rotate, thereby driving the transverse sliding frame 41 to slide. Of course, when the transverse sliding frame 41 is installed, appropriate limiting structures should be provided to prevent the transverse sliding frame 41 and the sliding block 421 from rotating synchronously with the driving rod 423.

[0056] With reference to Figure 2 , the mounting bracket 3 is further fixedly connected with a slide rail, and the transverse sliding frame 41 is fixedly connected with a sliding block. The sliding block is slidably connected with the slide rail. The number of slide rails can be one, two, three, etc. The number of sliding blocks corresponding to each slide rail can also be one or two. The number of slide rails and sliding blocks can be adjusted according to actual needs.

[0057] Here, the structure of the slide rail and the sliding block is a structure commonly used in the related field to realize sliding. The specific structure is not described again. The slide rail and the sliding block are used to limit the transverse sliding frame 41, thereby ensuring the smoothness and stability of the sliding of the transverse sliding frame 41.

[0058] With reference to Figure 3The lifting frame 51 is slidably connected with the horizontal moving frame 41. In order to improve the stability of the sliding connection between the lifting frame 51 and the horizontal moving frame 41, a sliding rail and sliding block matching structure is arranged between the lifting frame 51 and the horizontal moving frame 41. The sliding rail is fixedly connected with the horizontal moving frame 41, and the sliding block is fixedly connected with the lifting frame 51. For details, refer to the sliding rail and sliding block structure arranged between the horizontal moving frame 41 and the mounting support 3.

[0059] The longitudinal driving member 52 comprises two transmission wheels 521, a transmission belt 522 and a longitudinal driving motor 523. The two transmission wheels 521 are rotatably connected with the horizontal moving frame 41 and arranged in the longitudinal direction. The transmission belt 522 is arranged in tension between the two transmission wheels 521. When the transmission wheels 521 rotate, the transmission belt 522 is driven to rotate. The longitudinal driving motor 523 is fixedly connected with the horizontal moving frame 41. The output end of the longitudinal driving motor 523 is connected with one of the transmission wheels 521 to drive the transmission wheel 521 to rotate, thereby driving the transmission belt 522 to rotate. The lifting frame 51 is fixedly connected with one side of the transmission belt 522. In this way, the lifting frame 51 is driven to slide by the rotation of the transmission belt 522.

[0060] For example, the transmission wheel 521 is a belt pulley, and the transmission belt 522 is a belt. In other embodiments, in order to ensure the stability of the transmission between the transmission wheel 521 and the transmission belt 522, the transmission belt 522 is provided as a synchronous toothed belt. Correspondingly, the transmission wheel 521 is also provided with a matching toothed structure to ensure the stability of the transmission from the transmission wheel 521 to the transmission belt 522. In addition, the number of transmission wheels 521 can also be three, four, etc.

[0061] Reference Figure 3 The nucleic acid extractor movement mechanism further comprises a tension adjusting assembly 7 connected with the transmission wheel 521 for adjusting the distance between the two transmission wheels 521, so that the transmission belt 522 is always in a tensioned state between the two transmission wheels 521, which is conducive to improving the stability of the transmission.

[0062] For example, the two transmission wheels 521 are arranged in the vertical direction. The longitudinal driving motor 523 is connected with the upper transmission wheel 521, and the tension adjusting assembly 7 is connected with the lower transmission wheel 521 to drive the lower transmission wheel 521 to move up and down, thereby adjusting the distance between the two transmission wheels 521.

[0063] Specifically, the tension adjusting assembly 7 comprises a fixed block 71, a tension block 72 and an adjusting bolt 73. The fixed block 71 is fixedly connected with the horizontal moving frame 41, and the tension block 72 is slidably connected with the horizontal moving frame 41. The transmission wheel 51 is rotatably connected with the tension block 72. The tension block 72 is connected with the fixed block 71 through the adjusting bolt 73. By rotating the adjusting bolt 73, the tension block 72 is driven to displace relative to the fixed block 71.

[0064] Exemplarily, the adjusting screw 73 is rotationally connected with the fixing block 71 and is limited to displace relative to the fixing block 71, the adjusting screw 73 is threadedly connected with the tensioning block 72, and rotating the adjusting screw 73 can drive the tensioning block 72 to displace, so as to adjust the distance between the two transmission wheels 521, and make the transmission belt 522 keep in a tensioned state, thereby improving the stability of transmission.

[0065] With reference to Figure 3 , the lifting frame 51 is located between the horizontal moving frame 41 and the displacement base 61, a displacement hole is formed in the lifting frame 51, and the displacement base 61 is slidingly connected with the horizontal moving frame 41 through the displacement hole; specifically, the displacement base 61 is also fixedly connected with a sliding block, and the sliding block is slidingly connected with a sliding rail on the horizontal moving frame 41 through the displacement hole. Through the above structure, the lifting frame 51 and the displacement base 61 are slidingly connected with the horizontal moving frame 41 and share a sliding rail, which can simplify the structure and further improve the consistency of the sliding tracks of the lifting frame 51 and the displacement base 61, i.e., the consistency of the moving tracks of the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2 is higher, and deviation is avoided.

[0066] In other embodiments, a separate sliding rail and sliding block structure can be arranged between the lifting frame 51 and the displacement base 61 to realize stable sliding of the displacement base 61 relative to the lifting frame 51.

[0067] With reference to Figure 1 and Figure 5 , the displacement driving member 62 includes a displacement motor 621 fixed on the lifting frame 51 and a driving screw 622 rotationally connected with the lifting frame 51, one end of the driving screw 622 is rotationally connected with the magnetic rod sleeve assembly 2, and the other end is connected with the output end of the displacement motor 621 to realize rotational connection with the lifting frame 51 and rotation through the driving of the displacement motor 621.

[0068] With reference to Figure 3 , the lifting frame 51 is fixedly connected with a mounting base 54, and the mounting base 54 is exemplarily in a plate shape, and the displacement motor 621 is fixedly connected with the mounting base 54. In order to improve the stability of the driving screw 622, the one end of the driving screw 622 close to the displacement motor 621 can also be rotationally connected with the mounting base 54, which can improve the stability of the connection between the driving screw 622 and the lifting frame 51, and can also reduce the stress on the output end of the displacement motor 621, thereby reducing the risk of damage to the component.

[0069] In addition, the driving screw 622 passes through the magnetic rod assembly 1 and is threadedly connected with the magnetic rod assembly 1, specifically, the driving screw 622 passes through the frame of the magnetic rod assembly 1, and the specific structure of the magnetic rod assembly 1 is not introduced in the embodiments of the present application, and only the magnetic rod assembly 1 is exemplarily described as a whole.

[0070] In other embodiments, the driving screw 622 can also be arranged to pass through the displacement base 61 and threadedly engage the displacement base 61, and likewise can drive the magnetic rod assembly 1 to move or be stationary relative to the lifting frame 51.

[0071] When it is required to control the movement of the magnetic rod assembly 1 relative to the magnetic rod sleeve assembly 2, the displacement motor 621 is operated to drive the magnetic rod assembly 1 to slide through the driving screw 622, so as to realize the actions of inserting the magnetic rod into the magnetic rod sleeve and extracting the magnetic rod from the magnetic rod sleeve. When it is required to keep the magnetic rod stationary relative to the magnetic rod sleeve, the displacement motor 621 is in a non-working state, and correspondingly, the magnetic rod assembly 1 is stationary relative to the lifting frame 51, i.e., stationary relative to the magnetic rod sleeve assembly 2. In this state, the longitudinal driving motor 523 can be operated to realize the synchronous driving of the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2, and it is no longer required to control the two driving units separately, which reduces the complexity of control and improves the synchronization of the actions of the magnetic rod assembly 1 and the magnetic rod sleeve assembly 2, and can improve the quality of nucleic acid extraction.

[0072] One or more embodiments of the present specification are intended to cover all such alternatives, modifications and variations that fall within the broad scope of the appended claims. Therefore, any omission, modification, equivalent replacement, improvement, etc. made in the spirit and principle of one or more embodiments of the present specification should be included in the protection scope of the present disclosure.

[0073] The above is merely specific implementation manners of the present application, but the protection scope of the present application is not limited thereto. Any person skilled in the art can easily think of changes or replacements within the technical scope disclosed by the present application, and all such changes or replacements should be included in the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. A nucleic acid extractor motion mechanism, characterized by, The nucleic acid extractor comprises a mounting bracket fixed relative to a box body of the nucleic acid extractor; a transverse movement mechanism provided with a mounting position for displacement relative to the mounting bracket in a transverse direction; a longitudinal movement mechanism comprising a lifting frame slidingly connected to the mounting position and a longitudinal driving member provided on the mounting position, the longitudinal movement mechanism being configured to drive the lifting frame to slide; a displacement assembly comprising a displacement base provided on the lifting frame and a displacement driving member provided on the lifting frame, the displacement driving member being configured to drive the displacement base to slide relative to the lifting frame; wherein the lifting frame is configured to mount a magnetic rod sleeve assembly, and the displacement base is configured to mount a magnetic rod assembly.

2. The nucleic acid extractor motion mechanism of claim 1, wherein, The displacement driving member comprises a displacement motor fixed to the lifting frame and a driving screw rotatably connected to the lifting frame; the driving screw is threadedly engaged with the magnetic rod assembly or the displacement base; an output end of the displacement motor is connected to the driving screw to drive the driving screw to rotate.

3. The nucleic acid extractor motion mechanism of claim 2, wherein, The lifting frame is fixedly connected with a mounting base, and the displacement motor is fixedly connected to the mounting base; one end of the driving screw is rotatably connected to the magnetic rod sleeve assembly, and the other end is rotatably connected to the mounting base.

4. The nucleic acid extractor motion mechanism of claim 1, wherein, The mounting position is fixedly connected with a sliding rail; the lifting frame is fixedly connected with a sliding block, and the sliding block is slidingly engaged with the sliding rail; the displacement base is also fixedly connected with a sliding block, and the lifting frame is provided with a clearance hole, and the sliding block on the displacement base is slidingly connected to the sliding rail through the clearance hole.

5. The nucleic acid extractor motion mechanism of claim 1, wherein, The transverse movement mechanism comprises a transverse frame slidingly connected to the mounting bracket and a transverse driving member configured to drive the transverse frame to move; the mounting position is located on the transverse frame; the longitudinal driving member comprises at least two transmission wheels rotatably connected to the transverse frame, a transmission belt tautly arranged between the transmission wheels, and a longitudinal driving motor fixedly connected to the transverse frame, the longitudinal driving motor being connected to the transmission wheels to drive the transmission wheels to rotate; the lifting frame is fixedly connected to one side of the transmission belt.

6. The nucleic acid extractor motion mechanism of claim 5, wherein, It also comprises a tensioning adjusting assembly connected to the transmission wheels and configured to adjust the distance between the two transmission wheels located at two ends of the transmission belt.

7. The nucleic acid extractor motion mechanism of claim 6, wherein, The tensioning adjusting assembly comprises a fixed block fixed to the transverse frame, a tensioning block slidingly connected to the transverse frame, and an adjusting screw; the fixed block and the tensioning block are locked at a set distance by the adjusting screw; one of the transmission wheels located at one end of the transmission belt is rotatably connected to the tensioning block.

8. The nucleic acid extractor motion mechanism of claim 5, wherein, The transverse driving member comprises a sliding block fixedly connected to the transverse frame, a transverse driving motor fixedly connected to the mounting bracket, and a driving rod rotatably connected to the mounting bracket; the driving rod passes through the sliding block and is threadedly engaged with the sliding block; the transverse driving motor is connected to the driving rod to drive the driving rod to rotate.

9. The nucleic acid extractor motion mechanism of claim 8, wherein, The mounting bracket is also fixedly connected with a sliding rail; the transverse frame is fixedly connected with a sliding block, and the sliding block is slidingly engaged with the sliding rail.

10. A nucleic acid extraction instrument, characterized by, The nucleic acid extractor comprises the movement mechanism according to any one of claims 1-9.