Sample treatment equipment for detecting concentration of phenobarbital in human serum or plasma

Abstract

The utility model relates to the technical field of centrifugal machines, and discloses sample processing equipment for detecting the concentration of phenobarbital in human serum or plasma, which comprises a machine body, a motor is fixedly mounted at the bottom of an inner cavity of the machine body, a rotating shaft is fixedly mounted on an output shaft of the motor, and a centrifugal disc is fixedly mounted on the rotating shaft. Grooves are evenly formed in the centrifugal disc, test tube sleeves are movably connected in the grooves through shafts, a sliding groove is formed in the rotating shaft and located below the centrifugal disc, magnets with opposite magnetic poles are sequentially and fixedly installed in the sliding groove, a circular ring is movably connected to the rotating shaft in a sleeving mode, and the rotating shaft is provided with a rotating shaft. Electromagnetic sliding blocks are fixedly installed on the left portion and the right portion of the annular inner cavity correspondingly, the electromagnetic sliding blocks are matched with the sliding grooves, the inclination angle of the test tube sleeve is adjusted through sliding of the electromagnetic sliding blocks, insufficient sample centrifugation is prevented, the working efficiency of the device is improved, and the practicability of the device is promoted and improved; test tubes can be conveniently taken out.

Description

Technical Field

[0001] This utility model relates to the field of centrifuge technology, and in particular to a sample processing device for detecting the concentration of phenobarbital in human serum or plasma. Background Technology

[0002] Phenobarbital is a barbiturate sedative and hypnotic drug. Its central inhibitory effect varies with dosage. It has sedative, hypnotic, and anticonvulsant effects, and can also treat epilepsy. It is effective for generalized tonic-clonic seizures, focal seizures, and status epilepticus. It is less effective for petit mal seizures and is often ineffective for psychomotor seizures. Furthermore, using this drug alone may worsen the seizures. Its sodium salt is easily absorbed by both oral and injectable administration and can be distributed in various tissues and body fluids. Although it enters the human brain tissue slowly, the concentration in the brain tissue is the highest.

[0003] In the prior art, before detecting the concentration of phenobarbital in human serum or plasma, the human serum or plasma needs to be centrifuged. Most centrifuges have fixed test tube fixing devices. When the sample volume in the test tube is large or the types are different, the centrifugation may not be sufficient, and a second centrifugation operation is required, which affects the efficiency of the device. Therefore, in order to solve the above problems, this utility model proposes a sample processing device for detecting the concentration of phenobarbital in human serum or plasma. Utility Model Content

[0004] To address the shortcomings of existing technologies, this invention provides a sample processing device for detecting phenobarbital concentration in human serum or plasma. An electromagnetic slider moves a ring up and down, and a traction rod adjusts the tilt angle of the test tube sleeve. Increasing the tilt angle appropriately prevents insufficient centrifugation of the sample, enhances the device's efficiency, and improves its practicality. After centrifugation, the test tube sleeve is adjusted to a vertical position for easy removal of the test tubes by staff.

[0005] This utility model provides the following technical solution: a sample processing device for detecting phenobarbital concentration in human serum or plasma, comprising a body, a motor fixedly installed at the bottom of the inner cavity of the body, a rotating shaft fixedly installed on the output shaft of the motor, a centrifuge disc fixedly installed on the rotating shaft, six grooves evenly distributed on the centrifuge disc, a test tube sleeve movably connected to each groove via a shaft, two sliding grooves symmetrically distributed on the rotating shaft below the centrifuge disc, magnets with opposite poles fixedly installed sequentially in each sliding groove, a ring movably sleeved on the rotating shaft, electromagnetic sliders fixedly installed on the left and right sides of the inner cavity of the ring, the electromagnetic sliders engaging with the sliding grooves, six traction rods evenly movably connected to the side of the ring via a shaft, the other end of each traction rod movably connected to the bottom of the test tube sleeve via a shaft, the tilt angle of the test tube sleeve being adjusted by the sliding of the electromagnetic sliders to prevent insufficient centrifugation of the sample, enhance the working efficiency of the device, and improve its practicality.

[0006] Preferably, a heater is fixedly installed on the side of the test tube sleeve away from the centrifuge plate, and a heating coil is fixedly installed in the inner wall of the test tube sleeve cavity. The heating coil is fixedly connected to the heater. During the centrifugation process, the heater is turned on and heated by the heating coil to keep the serum sample in the test tube warm, so as to achieve a thorough centrifugation of the serum and facilitate the subsequent detection of phenobarbital.

[0007] Preferably, the upper part of the machine body is movably connected to a cover plate via a shaft. An observation window is provided on the cover plate. A sealing ring is fixedly installed at the bottom of the cover plate. A bearing is fixedly installed at the bottom of the cover plate and in the inner cavity of the sealing ring. The inner ring of the bearing is engaged with the top of the rotating shaft. Closing the cover plate and engaging the inner ring of the bearing with the top of the rotating shaft can effectively improve the stability of the rotating shaft driven by the motor and improve the stability of the centrifuge disc driven by the rotating shaft. The sealing ring seals the gap between the inner cavity of the machine body and the cover plate, enhancing the airtightness during centrifugation.

[0008] Preferably, a control panel is fixedly installed on the front of the machine body, and a heat dissipation vent is provided on the right side of the machine body. The device can be flexibly operated through the control panel. In the event of an emergency, it can be adjusted manually by the staff, which makes it easier to achieve the correct separation of serum samples.

[0009] Compared with the prior art, the present invention has the following beneficial effects:

[0010] 1. By energizing the electromagnetic slider, it slides on the groove, which in turn drives the ring to slide on the rotating shaft. During the movement of the ring, the traction rod drives the test tube sleeve to adjust the tilt angle, causing the test tube sleeve to tilt the test tube inward. When the tilt angle increases, it is more conducive to the centrifugation of the sample in the test tube, preventing insufficient centrifugation due to a large sample volume and avoiding the need for secondary centrifugation. This effectively enhances the working efficiency of the device. Compared with the completely fixed test tubes in traditional equipment, it improves the practicality of the device. After the sample centrifugation is completed, the test tube sleeve can be adjusted to a position perpendicular to the ground, making it convenient for staff to remove the test tube.

[0011] 2. After the test tube containing the sample is placed into the inner cavity of the device, the cover is closed and the inner ring of the bearing is engaged with the top of the rotating shaft. This effectively improves the stability of the rotating shaft driven by the motor and the stability of the centrifuge disc driven by the rotating shaft. The sealing ring seals the gap between the inner cavity of the device and the cover, enhancing the airtightness during centrifugation. The heater is turned on during centrifugation and heated by the heating coil to keep the serum sample in the test tube warm, ensuring thorough centrifugation of the serum and facilitating subsequent phenobarbital detection. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of the external structure of this utility model;

[0013] Figure 2 This is a schematic diagram of the structure of this utility model when it is opened;

[0014] Figure 3 This is a schematic diagram of the centrifuge disc structure of this utility model;

[0015] Figure 4 This is a schematic diagram of the bottom structure of the centrifuge disc of this utility model;

[0016] Figure 5 This is a schematic diagram of the cross-sectional structure of the slide groove of this utility model;

[0017] Figure 6 This is a schematic diagram of the cross-sectional structure of the test tube sleeve of this utility model;

[0018] Figure 7 This is a schematic diagram of the stable structure of this utility model.

[0019] In the diagram: 1. Machine body; 2. Motor; 3. Rotating shaft; 4. Centrifuge disc; 5. Groove; 6. Test tube sleeve; 7. Slide groove; 8. Magnet; 9. Ring; 10. Electromagnetic slider; 11. Traction rod; 12. Heater; 13. Heating coil; 14. Cover plate; 15. Observation window; 16. Sealing ring; 17. Bearing; 18. Control panel; 19. Heat dissipation vent. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0021] Please see Figures 1-7 A sample processing device for detecting phenobarbital concentration in human serum or plasma includes a body 1. A motor 2 is fixedly installed at the bottom of the inner cavity of the body 1. A rotating shaft 3 is fixedly installed on the output shaft of the motor 2. A centrifuge disc 4 is fixedly installed on the rotating shaft 3. The centrifuge disc 4 has six evenly spaced grooves 5. Test tube sleeves 6 are movably connected to the grooves 5 via shafts. Two sliding grooves 7 are provided on the rotating shaft 3 below the centrifuge disc 4. The sliding grooves 7 are symmetrically distributed on both sides. Magnets 8 with opposite magnetic poles are fixedly installed in the sliding grooves 7. A circular ring 9 is movably sleeved on the rotating shaft 3. Electromagnetic sliders 10 are fixedly installed on the left and right sides of the inner cavity of ring 9. The electromagnetic sliders 10 fit into the slide groove 7. Traction rods 11 are evenly and movably connected to the side of the ring 9 via shafts. There are six traction rods 11. The other end of the traction rods 11 is movably connected to the bottom of the test tube sleeve 6 via shafts. The rotating shaft 3 is driven by motor 2 to rotate, which in turn drives the centrifuge disc 4 to rotate. The centrifuge disc 4 drives the test tube sleeve 6 to rotate, thereby centrifuging the sample in the test tube. When the sample volume in the test tube is different, the electromagnetic sliders 10 are energized first. Since magnets 8 with opposite magnetic poles are fixedly installed in the slide groove 7 in sequence, When the electromagnetic slider 10 is energized, it generates a magnetic force that repels the magnet 8 in the slide groove 7, thereby pushing the electromagnetic slider 10 to move. When the electromagnetic slider 10 moves to the next magnet 8 with the opposite magnetic pole, the electromagnetic slider 10 is energized in the opposite direction, so that the electromagnetic slider 10 and the magnet 8 maintain a repulsive magnetic force, thus realizing the continuous movement of the electromagnetic slider 10. When the electromagnetic slider 10 needs to stop, the direction of the current on the electromagnetic slider 10 is not changed, so that it attracts the magnet 8 on the slide groove 7, thereby achieving the purpose of fixing the electromagnetic slider 10. Through the sliding of the electromagnetic slider 10 on the slide groove 7, it further... The ring 9 slides on the rotating shaft 3. During the movement of the ring 9, the traction rod 11 drives the test tube sleeve 6 to adjust the tilt angle, so that the test tube sleeve 6 drives the test tube to tilt inward. When the tilt angle increases, it is more conducive to the centrifugation of the sample in the test tube, preventing insufficient centrifugation due to a large sample volume, avoiding the need for secondary centrifugation, and effectively enhancing the working efficiency of the device. Compared with the completely fixed test tube fixing device in traditional equipment, it promotes the improvement of the device's practicality. After the sample centrifugation is completed, the test tube sleeve 6 can be adjusted to a position perpendicular to the ground, making it convenient for staff to take out the test tube.

[0022] A heater 12 is fixedly installed on the side of the test tube sleeve 6 away from the centrifuge tray 4. A heating coil 13 is fixedly installed in the inner wall of the test tube sleeve 6 cavity and is fixedly connected to the heater 12. A cover plate 14 is movably connected to the upper part of the machine body 1 via a shaft. An observation window 15 is provided on the cover plate 14, allowing the operator to observe the centrifugation process in real time. A sealing ring 16 is fixedly installed at the bottom of the cover plate 14. A bearing 17 is fixedly installed at the bottom of the cover plate 14 and inside the sealing ring 16 cavity. The inner ring of the bearing 17 is engaged with the top of the rotating shaft 3. An operation panel 18 is fixedly installed at the front of the machine body 1, and a heat dissipation device is located on the right side of the machine body 1. Open the cover plate 14 at port 19, seal the test tube containing the sample and place it into the inner cavity of the test tube sleeve 6. Close the cover plate 14 and make the inner ring of the bearing 17 engage with the top of the rotating shaft 3, which effectively improves the stability of the rotation of the rotating shaft 3 driven by the motor 2 and improves the stability of the rotation of the centrifuge disc 4 driven by the rotating shaft 3. The sealing ring 16 seals the gap between the inner cavity of the machine body 1 and the cover plate 14, enhancing the airtightness during the centrifugation process. During the centrifugation process, turn on the heater 12 and heat it through the heating coil 13 to keep the serum sample in the test tube warm and achieve full centrifugation of the serum, which is convenient for subsequent phenobarbital detection.

[0023] Working principle: After opening the cover plate 14, the test tube containing the sample is sealed and placed into the inner cavity of the test tube sleeve 6. The cover plate 14 is then closed, and the inner ring of the bearing 17 is engaged with the top of the rotating shaft 3. The sealing ring 16 seals the gap between the inner cavity of the machine body 1 and the cover plate 14. The motor 2 is started by controlling the control panel 18. The motor 2 drives the rotating shaft 3 to rotate, which in turn drives the centrifuge disc 4 to rotate. The centrifuge disc 4 drives the test tube sleeve 6 to rotate, thereby centrifuging the sample in the test tube. When the sample volume in the test tube is different, the electromagnetic slider 10 is energized first. Since magnets 8 with opposite magnetic poles are fixedly installed in the slide groove 7, energizing the electromagnetic slider 10 generates a magnetic force that repels the magnets 8 in the slide groove 7, thereby pushing the electromagnetic slider 10 to move. The electromagnetic slider 10 moves to the next opposite magnetic pole. When the magnet 8 is in the position, the electromagnetic slider 10 is reverse-energized, so that the electromagnetic slider 10 and the magnet 8 maintain a repulsive magnetic force, so that the electromagnetic slider 10 can move continuously. When the electromagnetic slider 10 needs to stop, the direction of the current on the electromagnetic slider 10 is not changed, so that it attracts the magnet 8 on the slide 7, thereby achieving the purpose of fixing the electromagnetic slider 10. By sliding the electromagnetic slider 10 on the slide 7, the ring 9 is driven to slide on the rotating shaft 3. During the movement of the ring 9, the traction rod 11 drives the test tube sleeve 6 to adjust the tilt angle, so that the test tube sleeve 6 drives the test tube to tilt inward. When the tilt angle increases, it is more conducive to the centrifugation of the sample in the test tube. During the centrifugation process, the heater 12 is turned on and heated by the heating coil 13, so that the sample in the test tube is kept at a constant temperature during the centrifugation process.

Claims

1. A sample processing apparatus for detecting the concentration of phenobarbital in human serum or plasma, comprising a body (1), characterized in that: The machine body (1) bottom fixed installation has the motor (2), the motor (2) output shaft fixed installation has the rotating shaft (3), the rotating shaft (3) fixed installation has centrifugal disc (4), the centrifugal disc (4) all uniformly on the recess (5) are set up, the recess (5) quantity is six, the recess (5) in through shaft movable joint has test tube cover (6), the rotating shaft (3) and located below centrifugal disc (4) are set up the chute (7), the chute (7) quantity is two and left and right symmetrical distribution, the chute (7) in order fixed installation has the magnet (8) of opposite magnetic pole, the rotating shaft (3) movable sleeve joint has the ring (9), the ring (9) inner chamber left and right two parts are fixed installation respectively electromagnetic slide block (10), the electromagnetic slide block (10) and chute (7) mutually fit, the ring (9) side through shaft even movable joint has the pull rod (11), the pull rod (11) quantity is six, the pull rod (11) other end through shaft movable joint in test tube cover (6) bottom.

2. The sample processing apparatus for detecting the concentration of phenobarbital in human serum or plasma according to claim 1, characterized by: The test tube cover (6) is fixedly installed with a heater (12) away from the centrifugal disc (4), and the heating coil (13) is fixedly installed in the cavity inner wall of the test tube cover (6). The heating coil (13) is fixedly connected with the heater (12).

3. The sample processing apparatus for detecting the concentration of phenobarbital in human serum or plasma according to claim 1, characterized by: The upper part of the machine body (1) is movably connected with a cover plate (14) through a shaft. An observation window (15) is formed in the cover plate (14). A sealing ring (16) is fixedly installed on the bottom of the cover plate (14). A bearing (17) is fixedly installed in the inner cavity of the sealing ring (16) on the bottom of the cover plate (14). The inner ring of the bearing (17) is clamped with the top end of the rotating shaft (3).

4. The sample processing apparatus for detecting the concentration of phenobarbital in human serum or plasma according to claim 1, characterized by: The front part of the machine body (1) is fixedly installed with a control panel (18). The right part of the machine body (1) is provided with a heat dissipation opening (19).

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