Centrifugal device for biological pharmacy

Abstract

The utility model discloses a centrifugal device for biopharmacy, which comprises a barrel, a cover plate is rotatably arranged on the barrel, a partition plate is fixedly arranged inside the barrel and divides the inside of the barrel into a working cavity and a motor cavity, a motor is fixedly arranged inside the motor cavity, and the motor is fixedly connected with a rotating shaft. The end, away from the motor, of the rotating shaft penetrates through the partition plate and then enters the working cavity, the rotating shaft is fixedly provided with a limiting rotating disc and a supporting rotating disc in the working cavity, a plurality of test tube holes are formed in the limiting rotating disc, and a clamping mechanism capable of rapidly fixing test tubes is arranged at the position, between the limiting rotating disc and the supporting rotating disc, of each test tube hole. A test tube is placed in the test tube groove and pressed, the circular ring and the base plate are driven to slide downwards, the two arc-shaped plates move relatively, the test tube is clamped, the plug pin is inserted into the long-strip sawtooth structure, and therefore the base plate is fixed, the position of the circular ring is fixed, the test tube is clamped, and operation is very convenient, easy and efficient.

Description

Technical Field

[0001] This utility model relates to the field of biopharmaceutical technology, specifically to a centrifuge device for biopharmaceutical applications. Background Technology

[0002] Biopharmaceuticals refer to products manufactured using research findings in microbiology, biology, medicine, and biochemistry, derived from organisms, tissues, cells, organs, and body fluids. These products utilize the principles and methods of microbiology, chemistry, biochemistry, biotechnology, and pharmacy for prevention, treatment, and diagnosis. High-speed centrifuges are frequently used in biopharmaceutical processes. They utilize the powerful centrifugal force generated by the high-speed rotation of the rotor to separate components in liquids and solid particles or liquid mixtures. This method is suitable for the rapid separation and synthesis of trace samples. The powerful centrifugal force generated by the centrifuge forces particles in the solution to overcome diffusion and settle. Centrifugation utilizes the powerful centrifugal force generated by the high-speed rotation of the centrifuge rotor to accelerate the sedimentation rate of particles in a liquid, separating substances with different sedimentation coefficients and buoyant densities in a sample.

[0003] In the prior art, a centrifuge device for biopharmaceutical use, with publication number "CN208526996U", includes a first shell and a second shell. The top of the first shell is connected to a cover plate via a movable mechanism. A cylinder is installed on the inner bottom surface of the second shell, and a high-speed motor is installed inside the cylinder. Multiple rubber pads are provided between the high-speed motor and the cylinder, and the multiple rubber pads are respectively adhered to the inner bottom surface and inner side surface of the cylinder. A switch is installed on the outside of the second shell, and the switch is connected to the high-speed motor via a wire. Multiple limiting mechanisms are installed at the bottom of the cylinder, which contact the upper surface of the high-speed motor. The limiting mechanism includes a baffle. One end of the baffle is connected to the cylinder via a locking screw, and the other end of the baffle extends to the upper surface of the high-speed motor. This not only improves the vibration damping effect of the high-speed motor, but also allows for adjustment and fixation according to the specifications of the test tubes.

[0004] However, existing technologies still have significant shortcomings, such as:

[0005] When the aforementioned centrifuge device for biopharmaceutical use fixes or removes test tubes, it does so by rotating the screw tube on the second screw, causing the push connecting plate to slide on the second screw and the mounting rod to adjust according to the length of the test tube and fix the test tube. However, the entire operation process is very cumbersome and takes a lot of time. Utility Model Content

[0006] The purpose of this invention is to provide a centrifuge device for biopharmaceutical applications to solve the problems mentioned in the background section.

[0007] To achieve the above objectives, this utility model provides the following technical solution:

[0008] A centrifuge for biopharmaceutical use includes a cylindrical body with a cover plate rotatably mounted on it. A partition plate is fixedly mounted inside the cylindrical body, dividing the interior of the cylindrical body into a working chamber and a motor chamber. A motor is fixedly mounted inside the motor chamber, and a rotating shaft is fixedly connected to the motor. The end of the rotating shaft away from the motor passes through the partition plate and enters the working chamber. A limiting turntable and a supporting turntable are fixedly mounted on the rotating shaft in the working chamber. The limiting turntable has several test tube holes.

[0009] A clamping mechanism that can quickly fix the test tube is provided at each test tube hole between the limiting turntable and the supporting turntable.

[0010] Preferably, the clamping mechanism includes two sliding rods fixed between the limiting turntable and the supporting turntable. Each of the two sliding rods is slidably fitted with a ring and a base plate. A plurality of connecting rods are fixedly arranged between the ring and the base plate. The base plate has a test tube groove. Two sliding holes are symmetrically opened on the ring. Two limiting holes are symmetrically opened on the base plate. A long strip is inserted into the sliding holes and the limiting holes. The two ends of the long strip are fixedly connected to the limiting turntable and the supporting turntable, respectively. The end of the long strip near the limiting turntable has a sloping structure, and the side near the supporting turntable has a serrated structure.

[0011] The limiting turntable is equipped with a clamping component that can hold the test tube;

[0012] The support turntable is equipped with a limiting component that can limit the position of the support turntable.

[0013] Preferably, the clamping assembly includes two arc-shaped plates movably disposed inside the ring, a movable rod is fixedly connected to the arc-shaped plates, the end of the movable rod away from the arc-shaped plates passes through the ring and enters the sliding hole, and is fixedly connected to an inclined block, and a compression spring is sleeved on the movable rod in the sliding hole.

[0014] Preferably, the limiting component includes a pin that is movably inserted into the chassis. The pin passes through the chassis and enters a limiting hole. A tension spring is provided on the outer sleeve of the pin. One end of the tension spring is fixedly connected to the pin, and the other end is fixedly connected to the outer wall of the chassis.

[0015] Preferably, the slope structure and the serrated structure of the strip are both half the length of the strip, and the slope structure of the strip is thinner at one end near the ring and thicker at the other end.

[0016] Preferably, a buffer cotton is fixedly installed inside the test tube groove.

[0017] Preferably, a cushioning cotton is fixedly provided on the side of the arc-shaped plate away from the movable rod.

[0018] Compared with the prior art, the beneficial effects of this utility model are:

[0019] 1. In use, this device simply requires placing the test tube into the test tube slot and pressing it down. This causes the ring and base to slide downwards. As the ring and base move downwards, the ramp structure on the long strip squeezes the inclined block, causing the two arc-shaped plates to move relative to each other, thus clamping the test tube. At this point, the pin inserts into the serrated structure of the long strip, fixing the base and thus the position of the ring, and the test tube is clamped. To remove the test tube, simply pull out the pin and slide the base upwards. The two arc-shaped plates will then move in opposite directions, allowing the test tube to be removed. Whether inserting and clamping the test tube or removing and releasing it, the operation is very convenient, easy, and efficient.

[0020] 2. This device can also simultaneously place test tubes of different types into it for centrifugation, without being limited by the type of test tube. It can ensure that the device can be filled with test tubes when it is working, thereby achieving the purpose of energy saving and high efficiency. Attached Figure Description

[0021] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0022] Figure 2 This is a cross-sectional structural diagram of the present invention;

[0023] Figure 3 This is a schematic diagram of the internal structure of the cylindrical body of this utility model;

[0024] Figure 4 This is a three-dimensional structural diagram of the clamping mechanism of this utility model;

[0025] Figure 5 This is a cross-sectional view of the clamping mechanism of this utility model;

[0026] Figure 6 for Figure 5 Enlarged diagram of area A in the middle;

[0027] Figure 7 for Figure 5 Enlarged diagram of area B in the middle.

[0028] In the diagram: 1. Cylinder; 2. Cover plate; 3. Divider plate; 4. Working chamber; 5. Motor chamber; 6. Motor; 7. Rotating shaft; 8. Limiting turntable; 9. Supporting turntable; 10. Test tube hole; 11. Sliding rod; 12. Ring; 13. Base plate; 14. Connecting rod; 15. Test tube groove; 16. Sliding hole; 17. Limiting hole; 18. Long strip; 19. Arc plate; 20. Movable rod; 21. Inclined block; 22. Compression spring; 23. Pin; 24. Tension spring. Detailed Implementation

[0029] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0030] Please see Figures 1-7 This utility model provides a technical solution:

[0031] Example 1:

[0032] A centrifuge device for biopharmaceutical use includes a cylindrical body 1. A cover plate 2 is rotatably mounted on the cylindrical body 1, and the cover plate 2 can be opened or closed by rotation. A partition plate 3 is fixedly mounted inside the cylindrical body 1, dividing the interior of the cylindrical body 1 into a working chamber 4 and a motor chamber 5. The working chamber 4 provides working space for centrifuging test tubes, and the motor chamber 5 provides working space for a motor 6. A motor 6 is fixedly mounted inside the motor chamber 5, and a rotating shaft 7 is fixedly connected to the motor 6. The end of the rotating shaft 7 away from the motor 6 passes through the partition plate 3 and enters the working chamber 4. Both the motor 6 and the rotating shaft 7 are located at the central axis of the cylindrical body 1. 7 is separate from the partition plate 3. The rotating shaft 7 can rotate at high speed in the middle of the partition plate 3. The rotating shaft 7 is fixedly provided with a limiting turntable 8 and a supporting turntable 9 in the working chamber 4. The limiting turntable 8 and the supporting turntable 9 can rotate at high speed together with the rotating shaft 7. The limiting turntable 8 has several test tube holes 10. Test tubes can be inserted through the test tube holes 10 and multiple test tubes can be separated without collision. A clamping mechanism that can quickly fix the test tube is provided at each test tube hole 10 between the limiting turntable 8 and the supporting turntable 9. The clamping mechanism can hold the test tube and rotate together with the limiting turntable 8 and the supporting turntable 9.

[0033] Example 2:

[0034] The clamping mechanism includes two sliding rods 11 fixed between the limiting turntable 8 and the supporting turntable 9. A ring 12 and a base 13 are slidably mounted on each sliding rod 11. The two sliding rods 11 pass sequentially through the ring 12 and the base 13, which are arranged parallel to each other. Several connecting rods 14 are fixedly installed between the ring 12 and the base 13, connecting the ring 12 and the base 13, allowing for synchronous up-and-down movement on the sliding rods 11. The base 13 has a test tube slot 15, inside which cushioning cotton is fixedly installed. The bottom of a test tube can be placed in the test tube slot 15, where the cushioning cotton provides a buffering effect to prevent the test tube from impacting the base 13. If the test tube breaks, two sliding holes 16 are symmetrically opened on the ring 12, and two limiting holes 17 are symmetrically opened on the base 13. The sliding holes 16 and the limiting holes 17 are aligned. A strip 18 is inserted into the sliding holes 16 and the limiting holes 17. The slope structure and the sawtooth structure of the strip 18 are both half the length of the strip 18. The slope structure of the strip 18 is thinner at one end near the ring 12 and thicker at the other end. The two ends of the strip 18 are fixedly connected to the limiting turntable 8 and the supporting turntable 9, respectively. The end of the strip 18 near the limiting turntable 8 is a slope structure, and the side near the supporting turntable 9 is a sawtooth structure. The limiting turntable 8 is equipped with a clamping component that can hold the test tube.

[0035] The clamping assembly includes two arc-shaped plates 19 movably disposed inside the ring 12. The two arc-shaped plates 19 are symmetrically arranged and can clamp the test tube in the middle. A cushioning cotton is fixedly disposed on the side of the arc-shaped plate 19 away from the movable rod 20 to cushion the pressure of the arc-shaped plate 19 on the test tube and prevent the test tube from being crushed. A movable rod 20 is fixedly connected to the arc-shaped plate 19. The end of the movable rod 20 away from the arc-shaped plate 19 passes through the ring 12 and enters the sliding hole 16, and is fixedly connected to the inclined block 21. A compression spring 22 is sleeved on the movable rod 20 in the sliding hole 16. The inclined block 21 fits against the slope structure of the strip 18.

[0036] Example 3:

[0037] The support turntable 9 is provided with a limiting component that can limit the support turntable 9. The limiting component includes a pin 23 that is movably inserted into the chassis 13. The pin 23 passes through the chassis 13 and enters the limiting hole 17. The pin 23 is covered by a tension spring 24 on the chassis 13. One end of the tension spring 24 is fixedly connected to the pin 23, and the other end is fixedly connected to the outer wall of the chassis 13. After the pin 23 passes through the limiting hole 17, it can be inserted into the serrated structure of the strip 18.

[0038] Working principle: During use, the cover plate 2 is first rotated open, and then the test tube is inserted into the test tube hole 10. Pressing the test tube down causes it to squeeze the base plate 13 and move it downward along the slide rod 11. The base plate 13 drives the ring 12 to move downward together through the connecting rod 14. When the ring 12 moves downward, the ramp structure on the long strip 18 will squeeze the inclined block 21 and compress the spring 22, causing the two arc plates 19 to move towards each other, thereby clamping the test tube. At the same time, the pin 23 is pulled by the tension of the tension spring 24 and inserts into the serrated structure of the long strip 18, thereby fixing the position of the base plate 13, which in turn fixes the position of the ring 12, thus clamping the test tube.

[0039] When the test tube is removed, pull the pin 23 to pull it out of the limiting hole 17, and then move the base 13 upward along the slide bar 11. The inclined block 21 is then subjected to the elastic force of the compression spring 22, causing the two arc plates 19 to move in opposite directions, so that the test tube will not be clamped, thereby removing the test tube from the device.

[0040] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A centrifugal device for biopharmaceuticals, comprising a barrel (1), a cover plate (2) is rotatably arranged on the barrel (1), a partition plate (3) is fixedly arranged in the barrel (1), and the partition plate (3) separates the barrel (1) into a working cavity (4) and a motor cavity (5), characterized in that: The motor cavity (5) is internally fixedly provided with a motor (6), the motor (6) is fixedly connected with a rotating shaft (7), one end of the rotating shaft (7) away from the motor (6) penetrates through the partition plate (3) and enters the working cavity (4), the rotating shaft (7) is fixedly provided with a limiting turntable (8) and a supporting turntable (9) in the working cavity (4), a plurality of test tube holes (10) are formed in the limiting turntable (8). A clamping mechanism capable of quickly fixing the test tube is arranged between the limiting turntable (8) and the supporting turntable (9) at each test tube hole (10).

2. The centrifugal device for biopharmaceuticals according to claim 1, characterized in that The clamping mechanism comprises two slide rods (11) fixed between the limiting turntable (8) and the supporting turntable (9), a circular ring (12) and a bottom disc (13) are slidably sleeved on the two slide rods (11), a plurality of connecting rods (14) are fixedly arranged between the circular ring (12) and the bottom disc (13), the bottom disc (13) is provided with a test tube groove (15), two slide holes (16) are symmetrically formed in the circular ring (12), two limiting holes (17) are symmetrically formed in the bottom disc (13), a long strip (18) is inserted into the slide holes (16) and the limiting holes (17), two ends of the long strip (18) are fixedly connected with the limiting turntable (8) and the supporting turntable (9) respectively, one end of the long strip (18) close to the limiting turntable (8) is of a slope structure, and the other end close to the supporting turntable (9) is of a sawtooth structure. The limiting turntable (8) is provided with a clamping assembly capable of clamping the test tube. The supporting turntable (9) is provided with a limiting assembly capable of limiting the supporting turntable (9).

3. The centrifugal device for biopharmaceuticals according to claim 2, characterized in that The clamping assembly comprises two arc-shaped plates (19) movably arranged in the circular ring (12), the arc-shaped plates (19) are fixedly connected with movable rods (20), one end of the movable rods (20) away from the arc-shaped plates (19) penetrates through the circular ring (12) and enters the slide holes (16), and is fixedly connected with an inclined block (21), and the movable rods (20) are sleeved with compression springs (22) in the slide holes (16).

4. The centrifugal device for biopharmaceuticals according to claim 2, characterized in that: The limiting assembly comprises a bolt (23) movably inserted into the bottom disc (13), the bolt (23) penetrates through the bottom disc (13) and enters the limiting holes (17), the bolt (23) is sleeved with a stretching spring (24) outside the bottom disc (13), one end of the stretching spring (24) is fixedly connected with the bolt (23), and the other end is fixedly connected with the outer side wall of the bottom disc (13).

5. The centrifugal device for biopharmaceuticals according to claim 2, characterized in that: The slope structure and the sawtooth structure of the long strip (18) are each half of the length of the long strip (18), the slope structure of the long strip (18) is thin at one end close to the circular ring (12) and thick at the other end.

6. The centrifugal device for biopharmaceuticals according to claim 2, characterized in that: The test tube groove (15) is fixedly provided with buffer cotton.

7. The centrifugal device for biopharmaceuticals according to claim 3, characterized in that: The arc-shaped plates (19) are fixedly provided with buffer cotton away from the movable rods (20).

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