Reagent shaking device for automatic IVD equipment
By designing a reagent mixing device for automated IVD equipment, the problem of reagent precipitation was solved, enabling automatic mixing and low-temperature storage of reagents, thus ensuring the accuracy of test results.
Patent Information
- Application Number
- CN202423323437.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-31
- Publication Date
- 2026-01-06
- Estimated Expiration
- 2034-12-31
AI Technical Summary
Existing automated IVD equipment cannot effectively mix reagents that require low-temperature storage and are prone to precipitation, thus affecting the test results.
Design a reagent mixing device for automated IVD equipment, comprising a base, reagent rack, reagent bottle, drive motor, transmission assembly, and temperature control assembly. The drive motor drives an eccentric wheel to rotate the reagent bottle, and the temperature sensor and cooling fan control the reagent temperature to ensure that the reagent is mixed at low temperature.
It enables automatic mixing of some reagents, avoids precipitation, ensures reagents are stored at low temperatures, extends shelf life, and improves detection accuracy.
Smart Images

Figure CN223769887U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of IVD equipment technology, specifically relating to a reagent shaking device for automated IVD equipment. Background Technology
[0002] Automated IVD (in vitro diagnostic) equipment refers to devices that improve diagnostic efficiency and accuracy through automation in the in vitro diagnostic process. Automated IVD equipment can automatically complete functions such as sample loading, centrifugation, decapping, testing, storage, disposal, retesting, and classification. These automated processes significantly improve production efficiency and reduce human error.
[0003] However, for some testing items, some reagents need to be shaken regularly and stored at low temperatures. Otherwise, precipitation may occur during the test, affecting the final experimental results. Existing automated IVD equipment processes a large number of samples at a time, and the reagents remain for a long time. The reagents with poor stability may affect the test results. Therefore, it is necessary to design a reagent shaking device suitable for automated IVD equipment. Summary of the Invention
[0004] The purpose of this invention is to provide a reagent mixing device that can be used in automated IVD equipment, automatically mixing some reagents in the automated IVD equipment and storing the reagents at low temperatures.
[0005] To achieve the above objectives, the technical solution adopted by this utility model is as follows:
[0006] The first aspect of this utility model provides a reagent mixing device for automated IVD equipment, the reagent mixing device comprising:
[0007] A base having a reagent receiving cavity, wherein the reagent receiving cavity has a slot extending along the front-back direction of the base, and multiple slots are arranged sequentially along the left-right direction of the base.
[0008] A reagent rack is detachably mounted in the slot. The rear end of the reagent rack is provided with a first reagent compartment and a platform located below the first reagent compartment. The first reagent compartment is open at both the top and bottom.
[0009] A reagent bottle, comprising a first reagent bottle, which is rotatably inserted into the first reagent compartment about its own axis and placed on the platform, wherein the lower end of the first reagent bottle is provided with a gear;
[0010] A drive motor is fixedly mounted on the base.
[0011] The transmission assembly includes an eccentric wheel and a rack. The center of the lower surface of the eccentric wheel is fixedly connected to the rotational output shaft of the drive motor. The upper surface of the eccentric wheel is provided with an eccentric shaft. The rack extends along the left-right direction of the base. One end of the rack is provided with a first slot extending along the front-back direction of the base. The eccentric shaft is movably inserted into the first slot. The other end of the rack is provided with a second slot extending parallel to the left-right direction of the base. A fixing member fixedly connected to the base is inserted into the second slot. The rack meshes with a gear of the first reagent bottle.
[0012] The temperature control component includes a temperature sensor disposed on the reagent containing cavity, a cooling fan and a refrigeration module disposed at the bottom of the base, the refrigeration module including a refrigeration device, and the temperature sensor, the cooling fan and the refrigeration device being electrically connected to each other.
[0013] In this invention, when the drive motor drives the eccentric wheel to rotate, it drives the rack to move. Under the limiting action of the first and second slots, the rack moves in a reciprocating linear motion in the left and right direction. Under the cooperation of the gear and rack at its bottom, the first reagent bottle moves in a reciprocating rotation in the clockwise and counterclockwise directions, thereby shaking the reagent in the first reagent bottle evenly.
[0014] In this invention, the temperature sensor can monitor the temperature of the reagent container cavity and transmit the signal to the cooling module and the cooling fan to achieve temperature control of the reagent container cavity. The cooling fan can dissipate the heat generated during the operation of the cooling system to prevent heat accumulation.
[0015] In this embodiment of the utility model, the drive motor is fixedly disposed on one side of the rear part of the base, and the left and right sides of the rear part of the base are respectively provided with a first limiting frame and a second limiting frame. The rack passes through the first limiting frame and the second limiting frame to further restrict the movement direction of the rack and improve the running stability.
[0016] Furthermore, the first limiting frame is located on the right side of the rear part of the base, near the eccentric wheel. The second limiting frame is located on the left side of the rear part of the base, and the fixing member inserted into the second strip groove is a bolt fixedly connected to the second limiting frame.
[0017] In this embodiment of the invention, the rotation output shaft of the drive motor extends along the vertical direction of the base, and the eccentric shaft extends upward from the upper surface of the eccentric wheel.
[0018] In this embodiment of the invention, the axis of the gear coincides with the axis of the first reagent bottle, and the tooth groove of the rack is located on the front side of the rack.
[0019] In this embodiment of the utility model, the reagent rack is provided with a snap-fit component at the rear end, and the base is provided with a baffle at the rear end, with a row of snap-fit holes on the baffle that can be connected to the snap-fit component.
[0020] In this embodiment of the invention, multiple second reagent compartments for placing reagent bottles are sequentially formed along the front-back direction of the reagent rack. The upper end of each second reagent compartment is open, and the lower end is closed. Each reagent bottle also includes multiple second reagent bottles that match the second reagent compartments. The number of reagent racks is one or more. This invention only requires shaking the reagents in the first reagent bottle; other reagents that do not require shaking can be stored in the second reagent bottles. Shaking the first reagent bottle does not affect other reagent bottles, and the presence of other reagent bottles does not affect the rotation of the first reagent bottle. This design results in low energy consumption and good stability.
[0021] In this embodiment of the invention, the front end of the reagent rack is provided with a gripping part, which facilitates inserting the reagent rack into the slot and removing the reagent rack from the slot.
[0022] The second aspect of this utility model also provides an IVD device, which includes the above-mentioned reagent shaking device.
[0023] In this embodiment of the invention, the IVD device further includes a robotic arm for automatic sampling and a control system for controlling the operation of the robotic arm.
[0024] Due to the application of the above technical solution, this utility model has the following advantages:
[0025] This invention relates to a reagent mixing device for automated IVD equipment. It can automatically mix only a portion of unstable reagents, and can simultaneously mix multiple reagents prone to precipitation, ensuring that precipitation does not affect the normal operation of the instrument. Furthermore, this reagent mixing device for automated IVD equipment can monitor and control the temperature in the reagent compartment, allowing the IVD equipment to store reagents under low-temperature conditions and extending their shelf life. Attached Figure Description
[0026] Figure 1 This is a three-dimensional structural schematic diagram of the reagent mixing device for automated IVD equipment in Example 1;
[0027] Figure 2 This is a three-dimensional structural diagram of the reagent mixing device for automated IVD equipment in Example 1 from another perspective.
[0028] Figure 3 This is a schematic diagram of the main structure of the reagent shaking device for automated IVD equipment in Example 1;
[0029] Figure 4 This is a rear view schematic diagram of the reagent mixing device for automated IVD equipment in Example 1;
[0030] Figure 5 This is a top view schematic diagram of the reagent mixing device for automated IVD equipment in Example 1;
[0031] Figure 6 This is a partial structural schematic diagram of the reagent mixing device for automated IVD equipment in Example 1;
[0032] Figure 7 for Figure 6 A top-view structural diagram;
[0033] Figure 8 This is a three-dimensional structural diagram of the reagent rack and reagent bottle of the reagent shaking device for automated IVD equipment in Example 1;
[0034] Figure 9 A schematic front view of the reagent rack and reagent bottles used in an automated IVD equipment reagent shaking device;
[0035] Figure 10 A top view of the reagent rack and reagent bottles used in an automated IVD equipment reagent mixing device;
[0036] Figure 11 This is a side view of the reagent rack and reagent bottles used in an automated IVD (in vitro diagnostic) equipment reagent mixing device.
[0037] The components include: 1. Base; 11. Reagent container; 12. Slot; 131. First limiting frame; 132. Second limiting frame; 14. Baffle; 141. Snap-fit hole; 2. Reagent rack; 21. First reagent compartment; 22. Platform; 23. Second reagent compartment; 24. Snap-fit part; 25. Grip; 31. First reagent bottle; 311. Gear; 32. Second reagent bottle; 4. Drive motor; 51. Eccentric wheel; 511. Eccentric shaft; 52. Rack; 521. Gear groove; 5221. First strip groove; 5222. Second strip groove; 6. Cooling fan; 7. Cooling module. Detailed Implementation
[0038] In the description of this utility model, it should be understood that the terms "front," "rear," "left," "right," etc., indicate the orientation or positional relationship based on the appendix. Figure 1 The orientations or positional relationships shown are for the purpose of facilitating the description of the present invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention.
[0039] In the description of this utility model, it should be understood that the term "a plurality of" includes at least two.
[0040] In the description of this utility model, unless otherwise explicitly specified and limited, the terms "connected," "fixed," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part. Those skilled in the art can understand the specific meaning of the above terms in the embodiments of this utility model according to the specific circumstances.
[0041] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0042] Example 1
[0043] like Figures 1-11 As shown, this embodiment provides a reagent shaking device for automated IVD equipment, which includes a base 1, a reagent rack 2, a reagent bottle, a drive motor 4, a transmission assembly, and a temperature control assembly.
[0044] In this embodiment, the base 1 is provided with a reagent receiving cavity 11, and the reagent receiving cavity 11 is provided with a slot 12 extending along the front-back direction of the base 1. Multiple slots 12 are arranged sequentially along the left-right direction of the base 1.
[0045] In this embodiment, the reagent rack 2 is detachably disposed in the slot 12. The rear end of the reagent rack 2 is provided with a first reagent compartment 21 and a platform 22 located below the first reagent compartment 21. The first reagent compartment 21 is open at both the top and bottom. Multiple second reagent compartments 23 for placing reagent bottles are also sequentially provided along the front-back direction of the reagent rack 2. The upper end of the second reagent compartment 23 is open and the lower end is closed.
[0046] In this embodiment, the reagent bottle includes a first reagent bottle 31, which is rotatably engaged in a first reagent compartment 21 around its own axis and placed on the platform 22. A gear 311 is provided at the lower end of the first reagent bottle 31. The reagent bottle also includes multiple second reagent bottles 32 that match the second reagent compartments 23. The number of reagent racks 2 is multiple, the same as the number of slots 12. A snap-fit member 24 is provided at the rear end of the reagent rack 2, and a baffle 14 is provided at the rear of the base 1. A row of snap-fit holes 141 are provided on the baffle 14 to engage with the snap-fit member 24. A gripping part 25 is provided at the front end of the reagent rack 2 to facilitate insertion and removal of the reagent rack 2 from the slots 12.
[0047] In this embodiment, the drive motor 4 is fixedly mounted on one side of the rear of the base 1, and the rotation output shaft of the drive motor 4 extends along the vertical direction of the base 1. The transmission assembly includes an eccentric wheel 51 and a rack 52. The center of the lower surface of the eccentric wheel 51 is fixedly connected to the rotation output shaft of the drive motor 4. An eccentric shaft 511 is provided on the upper surface of the eccentric wheel 51, and the eccentric shaft 511 extends upward from the upper surface of the eccentric wheel 51. The axis of the gear 311 coincides with the axis of the first reagent bottle 31. The rack 52 extends along the left-right direction of the base 1, and the tooth groove 521 of the rack 52 is located on the front side of the rack 52. One end of the rack 52 is provided with a first strip groove 5221 extending in the front-back direction of the base 1. The eccentric shaft 511 is movably inserted into the first strip groove 5221. The other end of the rack 52 is provided with a second strip groove 5222 extending in the left-right direction parallel to the base 1. A fixing member fixedly connected to the base 1 is inserted in the second strip groove 5222. The rack 52 meshes with the gear 311 of the first reagent bottle 31.
[0048] The base 1 has a first limiting frame 131 and a second limiting frame 132 on its left and right sides at the rear. The rack 52 passes through the first limiting frame 131 and the second limiting frame 132 to further restrict the movement direction of the rack 52 and improve the running stability. The first limiting frame 131 is located on the right side of the rear of the base 1, close to the eccentric wheel 51. The second limiting frame 132 is located on the left side of the rear of the base 1. The fixing component inserted into the second strip groove 5222 is a bolt fixedly connected to the second limiting frame 132. When the drive motor 4 drives the eccentric wheel 51 to rotate, it drives the rack 52 to move. Under the limiting action of the first strip groove 5221 and the second strip groove 5222, the rack 52 makes a reciprocating linear motion in the left and right direction. Under the cooperation of the gear 311 at its bottom and the rack 52, the first reagent bottle 31 makes a reciprocating rotation in the clockwise and counterclockwise directions, thereby shaking the reagent in the first reagent bottle 31 evenly.
[0049] In this embodiment, the temperature control component includes a temperature sensor mounted on the reagent compartment 11, a cooling fan 6 mounted on the bottom of the base 1, and a cooling module 7. The cooling module 7 includes a cooling device, and the temperature sensor, cooling fan 6, and cooling device are electrically connected to each other. The temperature sensor monitors the reagent compartment temperature and transmits signals to the cooling module 7 and cooling fan 6 to achieve temperature control of the reagent compartment. The cooling fan 6 dissipates the heat generated during the operation of the cooling system to prevent heat accumulation.
[0050] Example 2
[0051] This embodiment provides an IVD device, which includes the reagent shaking device of Embodiment 1, a robotic arm for automatic sampling, and a control system for controlling the operation of the robotic arm.
[0052] The above embodiments are only for illustrating the technical concept and features of this utility model, and are intended to enable those skilled in the art to understand the content of this utility model and implement it accordingly. They should not be construed as limiting the scope of protection of this utility model. All equivalent changes or modifications made in accordance with the spirit and essence of this utility model should be included within the scope of protection of this utility model.
Claims
1. A reagent shaking device for an automated IVD apparatus, characterized by: The reagent shaking device comprises: a base (1) provided with a reagent accommodating cavity (11), the reagent accommodating cavity (11) is provided with a clamping groove (12) extending along the front-rear direction of the base (1), a plurality of clamping grooves (12) are sequentially arranged along the left-right direction of the base (1); a reagent rack (2) detachably arranged in the clamping groove (12), the rear end of the reagent rack (2) is provided with a first reagent bin (21) and a platform (22) below the first reagent bin (21), the first reagent bin (21) is in an open state at both ends; a reagent bottle comprising a first reagent bottle (31), the first reagent bottle (31) is rotatably inserted into the first reagent bin (21) around its own axis and placed on the platform (22), the lower end of the first reagent bottle (31) is provided with a gear (311); a drive motor (4) fixedly arranged on the base (1); a transmission assembly comprising an eccentric wheel (51) and a rack (52), the center of the lower surface of the eccentric wheel (51) is fixedly connected with the rotating output shaft of the drive motor (4), the upper surface of the eccentric wheel (51) is provided with an eccentric shaft (511), the rack (52) extends along the left-right direction of the base (1), one end of the rack (52) is provided with a first strip-shaped groove (5221) extending along the front-rear direction of the base (1), the eccentric shaft (511) is relatively movably inserted into the first strip-shaped groove (5221), the other end of the rack (52) is provided with a second strip-shaped groove (5222) extending along the left-right direction of the base (1), the first strip-shaped groove (5221) is provided with a fixing member fixedly connected with the base (1), the rack (52) is meshingly connected with the gear (311) of the first reagent bottle (31), a temperature control assembly comprising a temperature sensor arranged on the reagent accommodating cavity (11), a heat dissipation fan (6) and a refrigeration module (7) arranged on the bottom of the base (1), the refrigeration module (7) comprises a refrigeration device, the temperature sensor and the heat dissipation fan (6) and the refrigeration device are respectively electrically connected.
2. The reagent shaking device for automated IVD devices of claim 1, wherein: The drive motor (4) is fixedly arranged on the rear side of the base (1), the left and right sides of the rear of the base (1) are respectively provided with a first limiting frame (131) and a second limiting frame (132), the rack (52) is arranged in the first limiting frame (131) and the second limiting frame (132).
3. The reagent shaking device for automated IVD devices of claim 2, wherein: The first limiting frame (131) is arranged on the right side of the rear of the base (1), the first limiting frame (131) is close to the eccentric wheel (51), the second limiting frame (132) is arranged on the left side of the rear of the base (1), the fixing member inserted into the second strip-shaped groove (5222) is a bolt fixedly connected with the second limiting frame (132).
4. The reagent shaking device for automated IVD devices of claim 1, wherein: The rotating output shaft of the drive motor (4) extends along the up-down direction of the base (1), the eccentric shaft (511) extends upward from the upper surface of the eccentric wheel (51).
5. The reagent shaking device for automated IVD devices of claim 1, wherein: The axis of the gear (311) coincides with the axis of the first reagent bottle (31), and the tooth groove (521) of the rack (52) is located on the front side of the rack (52).
6. The reagent shaking device for automated IVD devices of claim 1, wherein: The rear end of the reagent rack (2) is provided with a clamping piece (24), and the rear part of the base (1) is provided with a baffle (14) having a row of clamping holes (141) capable of being connected with the clamping piece (24).
7. The reagent shaking device for automated IVD devices of claim 1, wherein: A plurality of second reagent compartments (23) for placing reagent bottles are sequentially arranged along the front-rear direction of the reagent rack (2), the upper end of the second reagent compartment (23) is in an open state, and the lower end is in a closed state, the reagent bottles further include a plurality of second reagent bottles (32) matched with the second reagent compartment (23), and the number of the reagent racks (2) is one or more.
8. The reagent shaking device for automated IVD devices of claim 1, wherein: The front end of the reagent rack (2) is provided with a holding part (25).
9. An IVD device, characterized by: The IVD device comprises the reagent shaking device according to any one of claims 1 to 8.
10. The automated IVD device of claim 9, wherein: The IVD device further comprises a mechanical arm for automatic sampling and a control system for controlling the operation of the mechanical arm. The IVD device further comprises a mechanical arm for automatic sampling and a control system for controlling the operation of the mechanical arm.