Sample adding and mixing cuvette

Abstract

The utility model discloses a sample adding and mixing cuvette which comprises a sample adding container, a sample adding cavity is arranged in the sample adding container, the sample adding cavity is configured to preload a first reagent, a sample adding opening is formed in the upper end of the sample adding cavity, a sealing piece is detachably arranged at the sample adding opening of the sample adding container, and the sample adding opening is configured to add a sample to be detected; the valve body is mounted at the lower end of the sample adding container, the valve body is provided with a liquid inlet channel, a valve port and a liquid outlet channel which are sequentially communicated from top to bottom, and the liquid inlet channel is communicated with the sample adding cavity; the valve element is movably arranged in the valve port, and the valve element is configured to open or close the valve port; the colorimetric container is installed at the lower end of the valve body, a colorimetric cavity is formed in the colorimetric container, the colorimetric cavity is configured to be preloaded with a second reagent, at least part of the colorimetric cavity is defined by a light-transmitting side wall, and the colorimetric cavity is communicated with the liquid outlet channel. According to the cuvette, a sample solution to be detected is effectively prevented from spilling out, the functions of sample adding, mixing and colorimetric are integrally realized, and the professional requirement on operators is not high.

Description

Technical Field

[0001] This utility model relates to an instrument for measuring the turbidity of liquid samples, and particularly to a colorimetric cuvette. Background Technology

[0002] Colorimetric methods calculate turbidity values ​​based on the color intensity of the sample solution and a standard turbidity liquid, and are suitable for samples with turbidity less than or equal to 1000 NTU. Currently, the usual procedure involves first mixing a quantitative amount of the sample, reagent R1, and reagent R2 separately in a cuvette to allow a chemical reaction to occur. The cuvette is then shaken to thoroughly mix the sample solution, and finally, the turbidity of the sample solution in the cuvette is measured using a detection instrument. This entire process is complex, requires a high level of expertise from the operator, and the liquid in the cuvette is prone to spillage. Utility Model Content

[0003] The present invention aims to solve at least one of the technical problems existing in the prior art. To this end, the present invention proposes an integrated cup that simultaneously has the functions of sample addition, mixing, and colorimetry.

[0004] According to an embodiment of the present invention, a sample mixing cuvette includes: a sample container having a sample dispensing chamber pre-filled with a first reagent, the sample dispensing chamber having a sample dispensing port at its upper end, the sample container having a detachable sealing element at the sample dispensing port, the sample dispensing port being configured to dispense a sample to be tested; a valve body installed at the lower end of the sample container, the valve body having an inlet channel, a valve port, and an outlet channel sequentially connected from top to bottom, the inlet channel being connected to the sample dispensing chamber; a valve core movably disposed within the valve port, the valve core being configured to open or close the valve port; and a colorimetric container installed at the lower end of the valve body, the colorimetric container having a colorimetric chamber pre-filled with a second reagent, the colorimetric chamber being at least partially surrounded by a light-transmitting sidewall, the colorimetric chamber being connected to the outlet channel.

[0005] It has at least the following beneficial effects: When storing this cuvette, the valve core closes the valve port, sealing the sample addition chamber and the colorimetric chamber. The sample addition chamber is pre-filled with a quantitative amount of the first reagent, and the colorimetric chamber is pre-filled with a quantitative amount of the second reagent. When turbidity measurement is required, the sealing piece is removed from the sample addition port, and the sample to be tested is added to the sample addition chamber through the sample addition port. Then, the valve core is adjusted to open the valve port to connect the inlet and outlet channels, allowing the sample to be tested and the first reagent in the sample addition chamber to flow downward into the colorimetric chamber and mix with the second reagent, undergoing a chemical reaction. The valve core then closes the valve port again, sealing the colorimetric chamber. The cuvette is then shaken to thoroughly mix the sample solution, effectively preventing spillage. The turbidity of the sample solution in the colorimetric chamber is then measured by a detection instrument through the light-transmitting side wall from the outside. Thus, the functions of sample addition, mixing, and colorimetry are integrated, requiring minimal professional expertise from the operator.

[0006] According to some embodiments of the present invention, the valve core is provided with a docking channel. The valve core can rotate relative to the valve body along a first direction by a preset angle or slide a preset distance so that the docking channel connects the liquid inlet channel and the liquid outlet channel. The valve core can rotate relative to the valve body along a second direction by a preset angle or slide a preset distance so that the valve core blocks the liquid inlet channel and the liquid outlet channel. The first direction is opposite to the second direction.

[0007] According to some embodiments of this utility model, the valve core is a rotating body, the valve port is in the shape of a rotating body, the docking channel passes through the valve core in a direction perpendicular to the rotation center of the valve core, the valve core can rotate relative to the valve body in a first direction by a preset angle so that the docking channel connects the liquid inlet channel and the liquid outlet channel, and the valve core can rotate relative to the valve body in a second direction by a preset angle so that the rotating surface of the valve core blocks the liquid inlet channel and the liquid outlet channel.

[0008] According to some embodiments of the present invention, a valve stem is provided at one end of the valve core at the center of rotation.

[0009] According to some embodiments of this utility model, the preset angle is 90°.

[0010] According to some embodiments of the present invention, the light-transmitting sidewall is made of quartz glass.

[0011] According to some embodiments of the present invention, the light-transmitting sidewall includes a front sidewall, a left sidewall, a rear sidewall, and a right sidewall. The front sidewall, the left sidewall, the rear sidewall, and the right sidewall are connected end to end in sequence and are all planar structures. The front sidewall and the rear sidewall are parallel to each other, and the left sidewall and the right sidewall are parallel to each other.

[0012] According to some embodiments of this utility model, the sealing element is a sealing film.

[0013] According to some embodiments of this utility model, the sample dispensing cavity is funnel-shaped, wider at the top and narrower at the bottom.

[0014] According to some embodiments of this utility model, the sample to be tested is serum.

[0015] Additional aspects and advantages of this invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0016] The present invention will be further described below with reference to the accompanying drawings and embodiments, wherein:

[0017] Figure 1 This is a schematic diagram of the structure of the valve core when it blocks the inlet and outlet channels in an embodiment of the present invention;

[0018] Figure 2 for Figure 1 A sectional view;

[0019] Figure 3 This is a schematic diagram of the structure of this utility model when the docking channel connects the inlet channel and the outlet channel;

[0020] Figure 4 for Figure 3 A sectional view.

[0021] Reference numerals: 1. Sample addition container; 11. Sample addition chamber; 12. Sample addition port; 13. Sealing component; 2. Valve body; 21. Liquid inlet channel; 22. Liquid outlet channel; 23. Valve core; 3. Docking channel; 31. Rotating surface; 32. Colorimetric container; 4. Colorimetric chamber; 41. Transparent sidewall; 42. Valve stem; 5. Detailed Implementation

[0022] In the description of this utility model, it should be understood that the directional descriptions, such as up, down, front, back, left, right, etc., indicate the directional or positional relationship based on the directional or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0023] In the description of this utility model, the use of "first" and "second" is only for the purpose of distinguishing technical features and should not be construed as indicating or implying relative importance or implicitly indicating the number of technical features or the order of the technical features.

[0024] In the description of this utility model, unless otherwise explicitly defined, terms such as "setting," "installation," and "connection" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this utility model in conjunction with the specific content of the technical solution.

[0025] Reference Figures 1 to 4 This utility model discloses a sample mixing colorimetric cup, including a sample dispensing container 1, a valve body 2, a valve core 3, and a colorimetric container 4.

[0026] Among them, reference Figure 1 and Figure 2The sample container 1 has a sample dispensing chamber 11 inside, which is configured to pre-fill the first reagent. A quantitative amount of the first reagent is pre-stored in the sample dispensing chamber 11. A sample dispensing port 12 is provided at the upper end of the sample dispensing chamber 11. A sealing member 13 is detachably provided at the sample dispensing port 12. The sample dispensing port 12 is configured to add the sample to be tested. The sample to be tested can be added into the sample dispensing chamber 11 through the sample dispensing port 12.

[0027] It is understandable that the sealing component 13 is a sealing structure to achieve a tight seal at the sample dispensing port 12. Specifically, it can be a cap, which can be removed from the sample dispensing port 12 by flipping or unscrewing the cap. Alternatively, the sealing component 13 can be a sealing film, which can be removed from the sample dispensing port 12 by tearing or puncturing the sealing film. Of course, the sealing component 13 can also be any other sealing structure that can achieve a tight seal at the sample dispensing port 12 and can be removed from the sample dispensing port 12.

[0028] Reference Figure 1 and Figure 2 The valve body 2 is installed at the lower end of the sample loading container 1. The valve body 2 is provided with an inlet channel 21, a valve port 22 and an outlet channel 23 connected sequentially from top to bottom. The inlet channel 21 is connected to the sample loading chamber 11. The valve core 3 is movably disposed in the valve port 22. The valve core 3 is configured to open or close the valve port 22. When the valve core 3 opens the valve port 22, it means that the valve port 22 connects the inlet channel 21 and the outlet channel 23. When the valve core 3 closes the valve port 22, it means that the valve port 22 blocks the inlet channel 21 and the outlet channel 23.

[0029] Reference Figure 2 The colorimetric container 4 is installed at the lower end of the valve body 2. The interior of the colorimetric container 4 has a colorimetric chamber 41, which is configured to pre-fill with a second reagent. A quantitative amount of the second reagent is pre-stored in the colorimetric chamber 41. The colorimetric chamber 41 is connected to the liquid outlet channel 23. The colorimetric chamber 41 is at least partially surrounded by a light-transmitting sidewall 42. The light-transmitting sidewall 42 can transmit light, so as not to interfere with the colorimetric detection of the sample solution to be tested, and to facilitate the optical measurement of turbidity by the detection instrument.

[0030] It should be noted that the first reagent and the second reagent can be reagent R1 and reagent R2, or reagent R2 and reagent R1, respectively.

[0031] When storing this cuvette, refer to... Figure 1 and Figure 2 The valve core 3 closes the valve port 22, thus sealing the sample addition chamber 11 and the colorimetric chamber 41 respectively. The sample addition chamber 11 is pre-filled with a quantitative amount of the first reagent, and the colorimetric chamber 41 is pre-filled with a quantitative amount of the second reagent.

[0032] When turbidity measurement is required, remove the sealing piece 13 from the sample inlet 12, then add the sample to be tested into the sample inlet 11 through the sample inlet 12, and then adjust the valve core 3 as needed. Figure 3 and Figure 4 The valve 22 is opened to connect the inlet channel 21 and the outlet channel 23, allowing the sample to be tested and the first reagent in the sample addition chamber 11 to flow downward into the colorimetric chamber 41 and mix with the second reagent to undergo a chemical reaction. Then the valve core 3 closes the valve 22 to seal the colorimetric chamber 41. The colorimetric container 4 is then shaken to fully mix the sample solution and effectively prevent the sample solution from spilling out.

[0033] After the sample solution to be tested is uniformly mixed in the colorimetric chamber 41, the turbidity of the sample solution to be tested in the colorimetric chamber 41 is measured by the detection instrument through the light-transmitting sidewall 42 from the outside. Thus, the functions of sample addition, mixing and colorimetry are integrated, and the professional requirements of the operator are not high.

[0034] In some embodiments, refer to Figure 2 and Figure 4 The valve core 3 is provided with a docking channel 31. The valve core 3 can rotate relative to the valve body 2 in a first direction by a preset angle so that the docking channel 31 connects the liquid inlet channel 21 and the liquid outlet channel 23. The valve core 3 can rotate relative to the valve body 2 in a second direction by a preset angle so that the valve core 3 blocks the liquid inlet channel 21 and the liquid outlet channel 23. The first direction is opposite to the second direction.

[0035] Alternatively, the valve core 3 can be designed to slide a preset distance relative to the valve body 2 in the first direction so that the docking channel 31 connects the liquid inlet channel 21 and the liquid outlet channel 23, and the valve core 3 can slide a preset distance relative to the valve body 2 in the second direction so that the valve core 3 blocks the liquid inlet channel 21 and the liquid outlet channel 23.

[0036] Whether the valve core 3 is designed to slide relative to the valve body 2 or rotate relative to the valve body 2, the operation is very convenient.

[0037] In one specific design where the valve core 3 is rotated relative to the valve body 2, the valve core 3 is a rotating body, the valve port 22 is also rotating, and the docking channel 31 extends through the valve core 3 along the direction perpendicular to its rotation center. (Refer to...) Figures 1 to 4 The valve core 3 can rotate relative to the valve body 2 by a preset angle in the first direction so that the docking channel 31 connects the liquid inlet channel 21 and the liquid outlet channel 23. The valve core 3 can rotate relative to the valve body 2 by a preset angle in the second direction so that the rotating surface 32 of the valve core 3 blocks the liquid inlet channel 21 and the liquid outlet channel 23.

[0038] To facilitate the operator's rotation of the valve core 3, a valve stem 5 can be installed at one end of the valve core 3 at the center of rotation. Rotating the valve stem 5 allows the operator to apply force easily. The preset angle can be 90°. Each time the valve core 3 is rotated 90°, the valve port 22 can be switched between opening and closing.

[0039] In some embodiments, refer to Figure 1 The light-transmitting sidewall 42 is made of quartz glass and has very high light transmittance. Specifically, the light-transmitting sidewall 42 can include a front sidewall, a left sidewall, a rear sidewall, and a right sidewall. The front sidewall, left sidewall, rear sidewall, and right sidewall are connected end to end and are all planar structures. The planar structure can reduce the reflection and scattering of light. The front sidewall and the rear sidewall are parallel to each other, and the left sidewall and the right sidewall are parallel to each other. During turbidity detection, light enters vertically through one of the sidewalls and passes vertically through the opposite sidewall.

[0040] Reference Figure 1 In some embodiments, the sealing element 13 is a sealing film, which is attached to the sample dispensing port 12 of the sample dispensing container 1. The sealing element 13 can be removed from the sample dispensing port 12 by tearing or puncturing the sealing film. Figure 3 As shown.

[0041] In some embodiments, refer to Figure 3 The sample addition chamber 11 is funnel-shaped, wider at the top and narrower at the bottom, which facilitates the downward collection of the sample to be tested and the first reagent in the sample addition chamber 11 and their flow into the colorimetric chamber 41.

[0042] In some embodiments, the sample to be tested may be serum, enabling this cuvette to be used for the quantitative determination and analysis of specific functional proteins in serum.

[0043] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0044] Of course, this utility model is not limited to the above-described embodiments. Those skilled in the art can make equivalent modifications or substitutions without departing from the spirit of this utility model. All such equivalent modifications or substitutions are included within the scope defined by the claims of this application.

Claims

1. A sample loading mixing cuvette, characterized in that, The application relates to a sample adding device for a biochemical analyzer. The device comprises a sample adding container with a sample adding cavity configured to pre-store a first reagent, an upper end of the sample adding cavity being provided with a sample adding opening, the sample adding container being detachably provided with a sealing piece at the sample adding opening, and the sample adding opening being configured to add a sample to be measured. A valve body is installed at a lower end of the sample adding container, the valve body being provided with a liquid inlet channel, a valve opening and a liquid outlet channel which are sequentially communicated from top to bottom, and the liquid inlet channel being communicated with the sample adding cavity. A valve core is movably arranged in the valve opening, and the valve core is configured to open or close the valve opening. A colorimetric container is installed at a lower end of the valve body, the colorimetric container being internally provided with a colorimetric cavity configured to pre-store a second reagent, the colorimetric cavity being at least partially surrounded by a light-transmitting side wall, and the colorimetric cavity being communicated with the liquid outlet channel.

2. The sample application mixing cuvette of claim 1, wherein, The valve core is provided with a docking channel, the valve core being capable of rotating by a preset angle or sliding by a preset distance relative to the valve body in a first direction to make the docking channel communicate the liquid inlet channel and the liquid outlet channel, and the valve core being capable of rotating by a preset angle or sliding by a preset distance relative to the valve body in a second direction to make the valve core block the liquid inlet channel and the liquid outlet channel, the first direction being opposite to the second direction.

3. The sample application mixing cuvette of claim 2, wherein, The valve core is a rotary body, the valve opening is in the shape of a rotary body, the docking channel penetrates the valve core in a vertical direction of a rotation center of the valve core, the valve core is capable of rotating by a preset angle relative to the valve body in a first direction to make the docking channel communicate the liquid inlet channel and the liquid outlet channel, and the valve core is capable of rotating by a preset angle relative to the valve body in a second direction to make a rotary surface of the valve core block the liquid inlet channel and the liquid outlet channel.

4. The sample application mixing cuvette of claim 3, wherein, One end of the valve core on the rotation center is provided with a valve rod.

5. The sample application mixing cuvette of claim 4, wherein, The preset angle is 90 degrees.

6. The sample application mixing cuvette of claim 1, wherein, The light-transmitting side wall is made of quartz glass.

7. The sample application mixing cuvette of claim 6, wherein, The light-transmitting side wall comprises a front side wall, a left side wall, a rear side wall and a right side wall, the front side wall, the left side wall, the rear side wall and the right side wall are sequentially and circularly connected and are all in the structure of a plane, the front side wall and the rear side wall are parallel to each other, and the left side wall and the right side wall are parallel to each other.

8. The sample application mixing cuvette of claim 1, wherein, The sealing piece is a sealing film.

9. The sample application mixing cuvette of claim 1, wherein, The sample adding cavity is in the shape of a funnel with a wide upper end and a narrow lower end.

10. The sample application mixing cuvette of claim 1, wherein, The sample to be measured is serum.

Images