Biochemical sample treatment and analysis device

Abstract

The utility model relates to a biochemical sample treatment and analysis device, which comprises a box body, and a display module, a sample treatment module, a detection analysis module and a control system which are arranged in the box body, the sample treatment module comprises a sample box, a stock solution pool, a dilution pool and a pipetting platform positioned at the upper part of the box body, and a temperature control module is arranged below the sample box; the pipetting platform comprises a three-dimensional motion mechanism, a pipettor and a pipetting pump, the detection and analysis module comprises one or more of a photoelectric detection assembly, an ion detection assembly and an enzyme membrane detection assembly, and the control system is in communication connection with the sample processing module, the detection and analysis module and the display module.

Description

Technical Field

[0001] This utility model relates to the field of biochemical sample detection, specifically a biochemical sample processing and analysis device. Background Technology

[0002] In biochemical experiments, a common detection method involves extracting samples and placing them in specialized laboratory equipment for analysis of specific parameters. While this method is convenient for processing single indicators, it becomes inadequate when multiple parameters need to be measured simultaneously. This is because it requires a large amount of experimental equipment, and the frequent transfer of samples between different devices is not only complex but also prone to sample waste. Furthermore, the long storage time of samples between different devices and variations introduced by manual operation can significantly affect the accuracy and reliability of the test results. Utility Model Content

[0003] To address the aforementioned problems, this utility model provides a biochemical sample processing and analysis device, comprising a housing and a display module, a sample processing module, a detection and analysis module, and a control system disposed within the housing. The display module includes an operation display interface for function settings, data analysis, and processing. The sample processing module includes a sample container, a stock solution tank, a dilution tank, and a pipetting platform located on the upper part of the housing. The transfer of solution between the stock solution tank and the dilution tank is achieved through the pipetting platform. A temperature control module is disposed below the sample container. The pipetting platform includes a three-dimensional motion mechanism, a pipette, and a pipetting pump. The pipetting pump is connected to the pipette, and the three-dimensional motion mechanism drives the pipette to move. The stock solution tank is an open cavity at the top, with a waste outlet at the bottom and a sample inlet on the upper side. The dilution tank has a waste outlet at the bottom, a sampling port above the waste outlet, and a volume adjustment port and a water inlet at the top. The detection and analysis module includes one or more of a photoelectric detection component, an ion detection component, and an enzyme membrane detection component. The control system is communicatively connected to the sample processing module, the detection and analysis module, and the display module.

[0004] Preferably, the sample processing module includes a filtration tank, which is provided with an inlet, a sampling port, a drain port, an air port, and a pressure relief port, and the filtration tank contains a filter element.

[0005] Preferably, the chamber includes an ultraviolet disinfection lamp.

[0006] Preferably, the photoelectric detection component includes a syringe pump and a fiber optic spectrometer for detecting the solution in the syringe pump.

[0007] Preferably, the ion detection component includes an ion detection cell and an ion electrode.

[0008] Preferably, the enzyme membrane detection assembly includes an enzyme membrane reaction chamber and an enzyme membrane electrode.

[0009] Preferably, the number of dilution pools is two.

[0010] This invention includes functions such as filtration and dilution, and can perform real-time detection of multiple parameters of samples. It is easy to operate, highly automated, eliminates the need for frequent manual pipetting, and provides accurate and reliable test results while saving a lot of manpower. Attached Figure Description

[0011] The above and / or additional aspects and advantages of this invention will become apparent and readily understood from the description of the embodiments taken in conjunction with the following drawings, in which:

[0012] Figure 1 This is a front view of an embodiment of the present invention;

[0013] Figure 2 This is a schematic diagram of the structure of an embodiment of the present utility model;

[0014] Figure 3 This is a schematic diagram of the raw liquid tank according to an embodiment of this utility model;

[0015] Figure 4 This is a schematic diagram of the dilution tank according to an embodiment of the present invention;

[0016] Figure 5 This is a schematic diagram of the filter pool according to an embodiment of the present invention.

[0017] The components are as follows: 1. Housing; 2. Display module; 3. Sample box; 4. Stock solution tank; 5. Dilution tank; 6. Filtration tank; 7. Pipetting platform; 8. Temperature control module; 9. Three-dimensional motion mechanism; 10. Pipette; 11. Pipetting pump; 12. Waste outlet; 13. Sample inlet; 14. Waste discharge outlet; 15. Sampling port; 16. Volume adjustment port; 17. Water inlet; 18. Photoelectric detection component; 19. Syringe pump; 20. Fiber optic spectrometer; 21. Ion detection component; 22. Ion detection cell; 23. Ion electrode; 24. Enzyme membrane detection component; 25. Enzyme membrane reaction cell; 26. Enzyme membrane electrode; 27. Ultraviolet disinfection lamp; 28. Filtration tank; 29. ​​Inlet; 30. Sampling port; 31. Drain outlet; 32. Gas inlet; 33. Pressure relief port; 34. Filter element. Detailed Implementation

[0018] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0019] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0020] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, an electrical connection, or a connection that allows for communication; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0021] The following disclosure provides many different embodiments or examples for implementing various structures of this invention. To simplify the disclosure, specific examples of components and arrangements are described below. Of course, these are merely examples and are not intended to limit the scope of this invention.

[0022] See Figure 1-5 A biochemical sample processing and analysis device includes a housing 1 and a display module 2, a sample processing module, a detection and analysis module, and a control system disposed within the housing 1.

[0023] The display module 2 includes an operation display interface for function settings, data analysis and processing. In one embodiment, the operation display interface is a touch screen, on which sampling settings, detection parameters and other settings can be performed.

[0024] The sample processing module includes a sample box 3, a stock solution tank 4, a dilution tank 5, and a pipetting platform 7 located on the upper part of the box 1. The transfer of solution between the stock solution tank 4 and the dilution tank 5 is achieved through the pipetting platform 7.

[0025] The sample processing module is located inside the box 1. A temperature control module 8 is set below the sample box 3. The temperature can be set by the temperature control module 8, such as 4℃, to achieve sample retention and low-temperature preservation, ensuring that the bacteria in the sample stop growing.

[0026] The pipetting platform 7 includes a three-dimensional motion mechanism 9, a pipette 10, and a pipetting pump 11. The pipetting pump 11 is connected to the pipette 10, and the three-dimensional motion mechanism 9 drives the pipette 10 to move. The pipetting pump 11 is preferably a plunger pump. The pipette 10 can be equipped with 1mL, 5mL, or 10mL pipette tips or needles. The selection of the pipette tip or needle and its size is based on the volume of solution to be aspirated.

[0027] As shown in Figure 3, the stock solution tank 4 is an open cavity at the top. A waste liquid outlet 12 is provided at the bottom of the stock solution tank 4, and a sample inlet 13 is provided on the upper side. External solutions enter the stock solution tank 4 through the sample inlet 13.

[0028] A waste outlet 14 is located at the bottom of the dilution tank 5, a sampling port 15 is located above the waste outlet 14, and a volume-fixing port 16 and a water inlet 17 are located at the top. In chemical and biological analytical testing experiments, liquid samples often need to be diluted before analysis and testing. The purpose of dilution is to ensure that the concentration of the liquid sample to be tested is within the detection limit range. Specifically, a fixed amount of solution is drawn from the original solution tank 4 using a pipette platform 7 and injected into the dilution tank 5. Pure water is added to the dilution tank 5 through the water inlet 17 according to the dilution concentration. Excess solution is discharged from the volume-fixing port 16, thus completing the dilution process.

[0029] The dilution tank 5 is connected to the detection and analysis module through the sampling port 15. The diluted solution enters the detection and analysis module through this port. After all the tests are completed, the waste discharge port 14 is used to discharge the remaining solution in the dilution tank 5.

[0030] In some embodiments, the sample processing module includes a filter tank 28, which is provided with an inlet 29, a sampling port 30, a drain port 31, an air port 32, and a pressure relief port 33. The chamber contains a filter element. The solution to be filtered is input through the inlet 29, and air is drawn out through the air port 32. Under negative pressure, larger particles in the solution cannot pass through the filter element, and the solution enters the interior of the filter element. The filtered solution can be extracted through the sampling port 15 for subsequent operations.

[0031] The detection and analysis module includes one or more of the following: photoelectric detection component 18, ion detection component 21, and enzyme membrane detection component 24.

[0032] The control system communicates with the sample processing module, detection and analysis module, and display module 2. It is the central hub of the instrument and is used to control the operation of each module and process data.

[0033] Preferably, the biochemical sample processing and analysis device integrates a photoelectric detection component 18, an ion detection component 21, and an enzyme membrane detection component 24.

[0034] like Figure 1-2As shown, a photoelectric detection assembly 18 is installed on the outside of the housing 1. This assembly includes a syringe pump 19 and a fiber optic spectrometer 20 for detecting the solution within the syringe pump 19. The syringe pump 19 draws solution from the sampling port 15, and the fiber optic spectrometer 20 detects the solution in the syringe pump 19. Specifically, the syringe pump 19 has a transparent detection window, with optical fibers at both ends, and a detection light source and a fiber optic spectrometer detector connected to the optical fibers, respectively, for detecting the photoelectric detection indicators of the liquid sample. In one specific embodiment, the photoelectric detection assembly 18 is used to detect OD (Oxygen Demand).

[0035] The ion detection component 21 includes an ion detection cell 22 and an ion electrode 23. The ion electrode 23 includes one or more of the following: pH electrode, ammonium ion electrode, sodium ion electrode, potassium ion electrode, and calcium ion electrode.

[0036] The enzyme membrane detection assembly 24 includes an enzyme membrane reaction chamber 25 and an enzyme membrane electrode 26. The enzyme membrane can be any one or more of glucose enzyme membrane, lactase membrane, glutamate membrane, and lysine enzyme membrane. During detection, different enzymes are detected by changing different enzyme membranes in the reaction chamber.

[0037] In some implementations, there are two dilution tanks 5, which can meet the dilution requirements of different gradients.

[0038] Preferably, the chamber 1 includes an ultraviolet disinfection lamp 27 for sterilizing the internal environment of the chamber, ensuring that the instrument operates in a sterile environment.

[0039] Although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A biochemical sample processing and analyzing apparatus comprising a cabinet and a display module, a sample processing module, a detection and analysis module and a control system arranged in the cabinet, characterized in that, The display module comprises an operation display interface for function setting, data analysis and processing; The sample processing module comprises a sample box, a stock solution pool, a dilution pool and a pipetting platform located at the upper part of the box, the transfer of solution between the stock solution pool and the dilution pool is realized through the pipetting platform; a temperature control module is arranged below the sample box; the pipetting platform comprises a three-dimensional movement mechanism, a pipettor and a pipetting pump, the pipetting pump is connected to the pipettor, and the three-dimensional movement mechanism drives the pipettor to move; the stock solution pool is a cavity with an open upper part, a waste liquid port is arranged at the bottom of the stock solution pool, and a sample inlet is arranged at the side of the upper part; a waste discharge port is arranged at the bottom of the dilution pool, a sampling port is arranged above the waste discharge port, and a constant volume port and a water inlet are arranged at the upper part; The detection and analysis module comprises one or more of a photoelectric detection assembly, an ion detection assembly and an enzyme membrane detection assembly; The control system is communicatively connected to the sample processing module, the detection and analysis module and the display module.

2. The biochemical sample processing and analyzing apparatus according to claim 1, wherein The sample processing module comprises a filter pool, the filter pool is provided with an inlet, a sampling port, a drain port, an air port and a pressure relief port, and the filter pool comprises a filter core inside.

3. The biochemical sample processing and analyzing device according to claim 1, characterized in that The box comprises an ultraviolet disinfection lamp.

4. The biochemical sample processing and analyzing device according to claim 1, characterized in that The photoelectric detection assembly comprises a syringe pump and a fiber optic spectrometer for detecting the solution in the syringe pump.

5. The biochemical sample processing and analyzing device according to claim 1, characterized in that The ion detection assembly comprises an ion detection pool and an ion electrode.

6. The biochemical sample processing and analyzing device according to claim 1, characterized in that The enzyme membrane detection assembly comprises an enzyme membrane reaction pool and an enzyme membrane electrode.

7. The biochemical sample processing and analyzing device according to claim 1, characterized in that The number of the dilution pools is 2.

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