Rat simulation die body

Abstract

The utility model relates to a rat simulation model body, including the head, thorax, belly and tail end that connect in proper order, the thorax inside is provided with the lung tissue, the lung tissue and / or the tail end is provided with the deposit amount detection member that is used for monitoring the dose deposit value, through making the model of each part of the rat, the model can be used to detect the dose deposit value. The deposition amount detection component for monitoring the dose deposition value is arranged on the lung tissue and / or the tail end, a rat can be simulated, the deposition amount of the lung tissue and / or the tail end during proton irradiation is compared with the actually applied deposition amount, and the real conditions of the lung tissue and the tail end can be well simulated on the premise that the rat is not injured.

Description

Technical Field

[0001] This invention belongs to the field of proton irradiation dose deposition monitoring technology, and specifically relates to a rat simulation phantom. Background Technology

[0002] When evaluating whether protons can accurately reach the lung tissue and tail of animals in animal experiments, surgery is required. Rats are commonly used in these studies, but this is not only technically challenging but also carries a high risk of pneumothorax, a life-threatening condition. Furthermore, when monitoring dose deposition in lung tissue, the presence of air in the lungs can lead to lung collapse after euthanasia, potentially increasing the Hounsfield Unit (HU) value and reducing experimental accuracy.

[0003] Therefore, in order to address the above-mentioned technical problems, designing a rat simulation phantom that can accurately simulate the lung tissue and tail end without harming the rat is a technical problem that needs to be solved by those skilled in the art. Utility Model Content

[0004] To address the aforementioned issues, this invention provides a rat simulation phantom that can effectively simulate the lung tissue and / or tail end without harming the rat.

[0005] To achieve the above objectives, this utility model provides the following solution:

[0006] A rat simulation phantom includes a head, a thorax, an abdomen, and a tail connected in sequence. Lung tissue is disposed inside the thorax, and the lung tissue and / or the tail end are provided with a deposition amount detection component for monitoring dose deposition values.

[0007] Preferably, the deposition detection component is a Gafchromic EBT3 film, which is attached to the lung tissue and / or to the tail end.

[0008] Preferably, the Gafchromic EBT3 film is attached to the junction of the head and the thorax and / or to the junction of the abdomen and the end.

[0009] Preferably, one Gafchromic EBT3 film is used for both the lung tissue and the tail end.

[0010] Preferably, the deposition detection component is a thermoluminescent dosimeter, which is disposed inside the lung tissue and / or inside the tail end.

[0011] Preferably, at least three thermoluminescent dosing sheets are provided on the lung tissue and the tail end, respectively.

[0012] Preferably, the lung tissue and / or the tail end are provided with a small hole to accommodate the thermoluminescent dosing sheet.

[0013] Preferably, the axial dimension of the small hole is 2mm-3mm.

[0014] Preferably, the head, thorax, abdomen, and tail are detachable, the thorax and the lung tissue are detachable, and the thorax has a cavity for accommodating the lung tissue.

[0015] Preferably, it also includes a heart and a spine respectively disposed in the lung tissue and the abdomen.

[0016] Preferably, the head, thorax, abdomen, and tail are made of ABS plastic, the lung tissue is made of pine wood, and the spine and heart are made of PVDF polymer material.

[0017] The present invention achieves the following technical advantages over the prior art:

[0018] By creating models of various parts of a rat and installing deposition detection components to monitor the dose deposition value in the lung tissue and / or tail, rats can be simulated. The deposition amount in the lung tissue and / or tail during proton irradiation can be compared with the actual deposition amount applied. This can effectively simulate the real situation of the lung tissue and tail without harming the rat. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in this utility model or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0020] Appendix Figure 1 This is a schematic diagram of the overall structure of the rat simulation phantom disclosed in the embodiments of this utility model;

[0021] Appendix Figure 2 For the appendix Figure 1 A schematic diagram of the overall structure from the reverse view;

[0022] The components are: 1. Head; 2. Thoracic cavity; 3. Abdomen; 4. Tail end; 5. Tail end replacement module; 6. Lung tissue replacement module; 7. Heart; 8. Spine; 9. Small hole; 10. Lung tissue. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] The purpose of this invention is to provide a rat simulation phantom that can effectively simulate the lung tissue and / or tail end without harming the rat.

[0025] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the utility model will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0026] refer to Figure 1 and Figure 2 The rat simulation phantom disclosed in this embodiment of the present invention includes at least a head 1, a thorax 2, an abdomen 3, and a tail connected in sequence. The thorax 2 is provided with lung tissue 10, and the lung tissue 10 and / or the tail end 4 are provided with a deposition amount detection component for monitoring the dose deposition value. By modeling various parts of the rat and setting the deposition amount detection component for monitoring the dose deposition value in the lung tissue 10 and / or the tail end 4, the rat can be simulated. The deposition amount of the lung tissue 10 and / or the tail end 4 during proton irradiation can be compared with the actual deposition amount applied. The real situation of the lung tissue 10 and the tail end 4 can be well simulated without harming the rat.

[0027] It should be noted that in this embodiment, the dose deposition values ​​of the lung tissue and the tail end can be monitored simultaneously, or the dose deposition values ​​of the lung tissue or the tail end can be monitored separately.

[0028] refer to Figure 1 and Figure 2 In one implementation, the deposition detection component is a Gafchromic EBT3 film attached to the lung tissue 10 and the tail end 4. The Gafchromic EBT3 film can display the dose on a plane during proton irradiation. After proton irradiation, it needs to be compared with the planned dose. At the same time, the Gafchromic EBT3 film can also detect whether the dose received by the target tissue is uniform, thereby analyzing the dose deposition situation of the lung tissue 10 and the tail end 4. The Gafchromic EBT3 film can be cut to any size and is easy to attach, thereby improving experimental efficiency.

[0029] refer to Figure 1 and Figure 2As one implementation method, Gafchromic EBT3 film is attached to the junction of head 1 and thorax 2 and the junction of abdomen 3 and end. When it is necessary to attach Gafchromic EBT3 film, the relevant tissue can be removed directly and the Gafchromic EBT3 film can be attached, which can greatly improve experimental efficiency.

[0030] refer to Figure 1 and Figure 2 As one implementation method, one Gafchromic EBT3 film is set for each of the lung tissue 10 and the tail end 4.

[0031] refer to Figure 1 and Figure 2 As one implementation method, the deposition detection component is a thermoluminescent dosimeter disposed inside the lung tissue 10 and the tail end 4. The thermoluminescent dosimeter can detect very low radiation doses and has good long-term stability at room temperature, thereby improving monitoring accuracy.

[0032] refer to Figure 1 and Figure 2 In one embodiment, small holes 9 for accommodating thermoluminescent dosing sheets are provided inside the lung tissue 10 and the tail end 4. The small holes 9 facilitate the release of thermoluminescent dosing sheets, and placing the thermoluminescent dosing sheets inside the small holes 9 ensures that there are no gaps when the entire rat simulation model is put together.

[0033] It should be noted that: the number of small holes 9 on the lung tissue 10 is at least three, and five are provided in this embodiment; the number of small holes 9 on the tail end 4 is at least three, and five are provided in this embodiment.

[0034] refer to Figure 1 and Figure 2 In one embodiment, the axial dimension of the small hole 9 is 2mm-3mm.

[0035] refer to Figure 1 and Figure 2In one embodiment, the head 1, thorax 2, abdomen 3, and tail 4 are detachable. The thorax 2 and lung tissue 10 are also detachable. The thorax 2 has a cavity for accommodating the lung tissue 10. Making the head 1, thorax 2, abdomen 3, and tail 4 detachable makes it more convenient to attach and place Gafchromic EBT3 film or thermoluminescent dosimeter. Since the phantoms used for attaching Gafchromic EBT3 film and placing thermoluminescent dosimeter are different, making each tissue detachable allows for targeted replacement of relevant tissues when using different deposition detection components. For example, when selecting Gafchromic EBT3 film as the deposition detection component, lung tissue 10 and tail 4 without the small hole 9 are used. When selecting thermoluminescent dosimeter as the deposition detection component, lung tissue replacement module 6 with the small hole 9 and tail replacement module 5 are used, further improving the efficiency of the experiment.

[0036] It should be noted that the head 1, thorax 2, abdomen 3 and tail 4 can be connected by snap-fit, and the lung tissue 10 and thorax 2 can also be connected by snap-fit, as long as the detachable connection of each tissue can be achieved.

[0037] refer to Figure 1 and Figure 2 As one implementation method, the rat simulation phantom also includes a heart 7 and a spine 8 respectively set in the lung tissue 10 and the abdomen 3. By setting the heart 7 and spine 8 on the rat simulation phantom, it can fit more closely to the rat body and further improve the experimental accuracy.

[0038] refer to Figure 1 and Figure 2 As one implementation method, the head 1, thorax 2, abdomen 3, and tail 4 are made of ABS plastic because the HU value of ABS plastic is similar to that of the head 1, thorax 2, abdomen 3, and tail 4. The lung tissue 10 is made of pine wood because the HU value of pine wood is similar to that of the lung tissue 10. The spine 8 and heart 7 are made of PVDF polymer material because the HU value of PVDF polymer material is similar to that of the spine 8 and heart 7. By setting the material of each tissue to a HU value similar to that of the responding tissue, the accuracy of the experiment can be further guaranteed.

[0039] Any adaptive changes made according to actual needs are within the protection scope of this utility model.

[0040] It should be noted that, for those skilled in the art, it is obvious that this utility model is not limited to the details of the above exemplary embodiments, and that this utility model can be implemented in other specific forms without departing from the spirit or essential characteristics of this utility model. Therefore, the embodiments should be considered as exemplary and non-limiting in all respects, and the scope of this utility model is defined by the appended claims rather than the foregoing description. Therefore, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within the utility model. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. A rat simulation phantom, characterized in that, It comprises a head, a thorax, an abdomen and a tail end connected in sequence, the thorax is internally provided with lung tissue, the lung tissue and / or the tail end is provided with a deposition amount detection component for monitoring the dose deposition value.

2. Rat phantom according to claim 1, characterized in that The deposition amount detection component is Gafchromic EBT3 film, which is attached to the lung tissue and / or the tail end.

3. Rat phantom according to claim 2, characterized in that The Gafchromic EBT3 film is attached to the joint of the head and the thorax and / or the joint of the abdomen and the tail end.

4. The rat phantom of claim 1, wherein, The deposition amount detection component is a thermoluminescence dosimeter, which is arranged inside the lung tissue and / or the tail end.

5. Rat phantom according to claim 4, characterized in that The lung tissue and the tail end are respectively provided with at least three thermoluminescence dosimeters.

6. The rat phantom of claim 4, wherein, The inside of the lung tissue and / or the tail end is provided with a small hole for accommodating the thermoluminescence dosimeter.

7. Rat phantom according to claim 6, characterized in that The axial size of the small hole is 2mm-3mm.

8. The rat phantom of claim 1, wherein, The head, the thorax, the abdomen and the tail end are detachably arranged, the thorax and the lung tissue are detachably arranged, and the thorax is internally provided with an accommodating cavity for accommodating the lung tissue.

9. The rat phantom of claim 1, wherein, It also comprises a heart and a spine arranged in the lung tissue and the abdomen respectively.

10. The rat phantom of claim 9, wherein, The head, the thorax, the abdomen, the tail end are made of ABS plastic, the lung tissue is made of pine, and the spine and the heart are made of high molecular material PVDF.

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