Multifunctional slide rack and dyeing assembly

Abstract

The multifunctional slide rack comprises a slide rack base and a heating table, the left outer side face and the right outer side face of the heating table are rotationally connected with the inner side of the top of the slide rack base, and the edge of the bottom face of the front portion of the heating table is attached to the top face of the slide rack base; a push rod is arranged in the slide rack base, the fixed end of the push rod is rotationally connected with the inner bottom surface of the slide rack base, the output end of the push rod is rotationally connected with the center of the bottom surface of the front part of the heating table, and the push rod is obliquely upwards arranged from the rear part to the front part of the heating table; a flow guide groove is obliquely and downwards formed in the rear part of the slide rack base, is positioned below the heating table, and extends to the rear part of the slide rack base, and the output end upwards pushes the bottom surface of the front part of the heating table to drive the rear part of the heating table to incline towards the flow guide groove. The multifunctional slide rack is matched with a dyeing assembly, any slide can be independently controlled, and the multifunctional slide rack has the functions of inclined cleaning, slide detection, temperature control and uniform vibration.

Description

TECHNICAL FIELD

[0001] The utility model relates to cell slide dyeing technical field and particularly relates to a multifunctional slide rack and dyeing assembly. BACKGROUND

[0002] The immunohistochemical dyeing technology is widely applied in clinical case diagnosis and scientific research, which mainly applies the basic principle of specific combination of immunological antigen and antibody, and makes the color developing agent of the marked antibody develop color through chemical reaction, so as to qualitatively, positionally and relatively quantitatively study the antigen (mainly protein) in the tissue cell.

[0003] In the process of immunohistochemical dyeing, biological samples need to be placed on a carrier slide, and the biological samples are dyed on the carrier slide through reagents. The immunocyte dyeing steps include processes such as dewaxing, antigen repair, antigen-antibody reaction, enzyme catalytic chemical reaction, re-dyeing, and washing. At present, there are full-automatic immunohistochemical dyeing machines on the market, which are widely used in conventional pathological diagnosis and scientific research. However, the existing immunohistochemical dyeing equipment and method need a long detection time, and cannot perform rapid immunohistochemical dyeing on frozen sections, so that doctors cannot make accurate diagnosis on frozen sections in a short time.

[0004] A Chinese invention patent with patent number CN115184122A proposes an automatic dyeing instrument slide stage device that cooperates with a slide pulling mechanism, including a workbench, a rack, a heating table, and a waste liquid extraction device. The rack is evenly configured with several heating tables, and each heating table is correspondingly provided with a liquid discharge block at one end. A liquid discharge cavity is formed in the liquid discharge block, and the lower end of the liquid discharge cavity is connected with the waste liquid extraction device. The liquid discharge cavity uses the viscosity of liquid to extract the waste liquid on the reaction slide through the reaction cover. Each heating table is provided with a corresponding reaction cover above it. One end of the reaction cover is detachably connected with the slide pulling mechanism. The reaction cover is used to cover the reaction slide during use. By adjusting the position of the reaction cover relative to the reaction slide, different working stages can be corresponded. The reaction cover includes a liquid adding area, a reaction area, a drainage area, and a liquid accumulation area. The liquid adding area, the reaction area, the drainage area, and the liquid accumulation area are arranged in a ladder shape. The liquid accumulation area is connected with the drainage area. The reaction area on the reaction cover is an upper concave area with a depth less than 1mm. The surface of the reaction slide is horizontally arranged. The reaction area on the reaction cover is provided with a slide reaction area defined by a hydrophobic coating. The reaction area on the reaction cover and the slide reaction area on the reaction slide cooperate to form a dry slide reaction chamber that uses the principle of siphon to attract liquid accumulation.

[0005] In summary, the slide rack in the prior art not only has the problems of insufficient cleaning and inconvenient waste liquid collection, but also is susceptible to the influence of reaction temperature and insufficient contact of reagents on the reaction of the slide and the reagents, resulting in insufficient reaction and long time consumption. Utility model content

[0006] In view of the problems in the prior art, the utility model provides a multifunctional slide rack and a staining assembly to solve the above problems.

[0007] According to a first aspect of the present application, a multifunctional slide rack is provided, comprising a slide rack base and a heating table, the left and right outer sides of the heating table are rotationally connected to the top inner side of the slide rack base, and the front bottom edge of the heating table is attached to the top surface of the slide rack base; the inside of the slide rack base is provided with a push rod, the fixed end of the push rod is rotationally connected to the inner bottom surface of the slide rack base, the output end of the push rod is rotationally connected to the center of the front bottom surface of the heating table, and the push rod is obliquely upwardly arranged from the rear part to the front part of the heating table; the rear part of the slide rack base is obliquely downwardly provided with a flow guide groove, the flow guide groove is located below the heating table, and the flow guide groove extends to the rear of the slide rack base; the output end pushes the front bottom surface of the heating table upwardly, and drives the rear part of the heating table to be obliquely inclined to the flow guide groove.

[0008] By adopting the above technical solution, the heating table and the slide rack base are rotationally connected, when the bottom surface of the heating table is parallel to the slide rack base, the front bottom edge of the heating table can be supported by the top surface of the slide rack base, and the push rod can also provide stable support force, so that the heating table is prevented from being overturned, during the process of cleaning the slide with reagents, the push rod can push the heating table to be overturned, so that the rear part of the heating table is overturned and obliquely inclined to the flow guide groove by a certain angle, so that the reagents can flow into the flow guide groove from the rear part of the heating table, and then flow into the waste liquid collection platform through the flow guide groove.

[0009] Preferably, the slide rack base comprises a bottom plate, a front panel, a rear cover plate, a left side plate and a right side plate, the front panel, the rear cover plate, the left side plate and the right side plate are respectively connected to the front, rear, left and right edges of the bottom plate and cooperatively form a cavity for accommodating the push rod, and the top of the cavity is provided with an opening corresponding to the position of the heating table.

[0010] By adopting the above technical solution, the front panel, the rear cover plate, the left side plate and the right side plate are cooperatively arranged along the edges of the bottom plate to form the cavity for accommodating the push rod, the top of the cavity is provided with the opening, so that the output end of the push rod can be cooperated with the bottom surface of the heating table from the position of the opening, and meanwhile, the front panel, the rear cover plate, the left side plate and the right side plate cooperatively form a complete top surface, and the front bottom surface of the heating table can be attached to the top surface.

[0011] Further preferably, the outer side upper portion of the left side plate and the right side plate is provided with an embedded groove, a connecting plate is installed in the embedded groove, the connecting plate is connected with the hole position of the embedded groove through a limiting hole, the limiting hole is a long round hole extending to the front panel and the back cover plate, and the width of the embedded groove is greater than the width of the connecting plate.

[0012] By adopting the above technical scheme, the additional connecting plate facilitates the cooperation of the slide rack base and the heating table, and the design of the limiting hole as a long round hole enables the position of the connecting plate in the embedded groove to be adjusted in the front-back direction, thereby improving the installation accuracy and facilitating the installation.

[0013] Further preferably, the top of the connecting plate penetrates a rotating shaft, the left and right outer sides of the heating table are provided with corresponding waist-shaped holes, a bushing is embedded and installed in the waist-shaped hole, and the rotating shaft is rotationally connected with the bushing.

[0014] By adopting the above technical scheme, the design of the waist-shaped hole, the bushing and the rotating shaft can prevent the left and right sides of the heating table from being eccentric with the slide rack base during assembly, and also enables the heating table to reduce wear and tear and be more convenient to install and replace in a working environment that often needs to be turned over.

[0015] Further preferably, the upper surface of the rear portion of the bottom plate is provided with a rotating seat, the bottom surface of the rotating seat is provided with an installation hole connected with the hole position of the bottom plate surface, the installation hole is a long round hole extending to the front panel and the back cover plate, and the fixed end of the push rod is rotationally connected with the rotating seat.

[0016] By adopting the above technical scheme, the rotating seat can have a certain adjustment space when cooperating with the bottom plate, the position of the rotating seat is adjusted forward and backward, thereby changing the installation position of the fixed end of the push rod, and the adjustability is achieved.

[0017] Further preferably, the front bottom surface of the heating table is vertically provided with left-right symmetrical studs, the output end of the push rod is provided with a push hole guided left and right, a pull spring is arranged in the push hole, and the pull hooks of the pull spring are fixed on the studs on the left and right sides.

[0018] By adopting the above technical scheme, when the push rod is installed, the position of the rotating seat is adjusted backward, the pull spring is pulled tight in the backward direction, in the process of turning over the heating table, the output end of the push rod extends different lengths to drive the heating table to turn over different angles, the output end of the push rod pushes the heating table upward to turn it over, and when the heating table needs to be reset, the heating table can be accurately restored to the position under the elastic force of the pull spring.

[0019] Further preferably, the heating table comprises, from bottom to top, a heating table base, a floating assembly, a heating table body and a glass slide, the end points of the heating table base are connected with the heating table body through the floating assembly; the top surface of the heating table body is provided with a slide groove for placing the glass slide, the front end of the glass slide is provided with an identification code, the heating table base is provided with an identification hole corresponding to the position of the identification code, and a sensor is installed below the identification hole.

[0020] By adopting the above technical scheme, the heating table base is connected with the heating table body through the floating assembly, the end point height of the heating table body can be adjusted by the floating assembly during installation, and the heating table base and the heating table body are flexibly connected, thereby avoiding the phenomenon that the levelness of the upper surface of the heating table body is not enough, causing the liquid to flow out of the glass slide, and meanwhile, the position of the identification code on the glass slide corresponds to the position of the identification hole, the sensor can monitor the identification code through the identification hole, and whether the glass slide is placed in the slide groove is determined by judging the identification code.

[0021] Further preferably, the rear end and the left and right sides of the slide groove are provided with vertical columns, the vertical columns are arranged close to the rear end surface and the left and right side surfaces of the glass slide; the left and right sides of the rear part of the slide groove are provided with drainage grooves extending to the rear end and inclined, the outlet of the drainage groove is located above the guide groove, and the guide groove is inclinedly installed on the top of the rear cover plate.

[0022] By adopting the above technical scheme, the vertical columns prevent the glass slide from falling out of the slide groove during the staining process, and the inclined drainage grooves can drain the excess reagent to the rear end of the slide groove, effectively preventing the problems of splashing and liquid accumulation.

[0023] Further preferably, the rear bottom surface of the heating table body is upwardly provided with a heating vibration groove, a heating film is attached to the top surface of the heating vibration groove, a thermistor is arranged on the heating film, and a plurality of vibration assemblies are further arranged below the heating film.

[0024] By adopting the above technical scheme, the heating film is used to heat the glass slide on the slide groove from below, and the thermistor can monitor the heating temperature in real time, since different reaction reagents require different reaction temperatures, the thermistor is used to control the temperature of the heating film, which can improve the reaction effect of different reagents, the vibration assemblies below the heating film can provide power for the heating table body, thereby driving the glass slide to vibrate, and the floating assembly can also reduce the noise generated during vibration, increase the collision and combination efficiency of the reagent and the antibody in the glass slide, and shorten the required reaction time.

[0025] According to the second aspect of the present application, a dyeing assembly is provided, which comprises the multifunctional slide rack described above, further comprises an assembly base plate and a plurality of parallel guide rails arranged on the upper surface of the assembly base plate, one end of the guide rail is provided with a pulley, the other end of the guide rail is further provided with a driving motor, the driving motor is connected with the pulley through a synchronous belt, and the bottom surface of the slide rack base is slidably arranged on the guide rail and connected with the surface of the synchronous belt; further comprising a waste liquid collection platform, the waste liquid collection platform is arranged at one end of the guide rail and corresponds to the position of the flow guide groove.

[0026] By adopting the above technical scheme, the multifunctional slide racks on each guide rail are independently controlled by a separate driving motor, the slide rack base is driven to move forward and backward along the two ends of the guide rail through the cooperation of the driving motor, the pulley and the synchronous belt, when the slide rack base is driven to one end close to the waste liquid collection platform, the flow guide groove can cooperate with the waste liquid collection platform to collect excess liquid, and during the cell dyeing process, one multifunctional slide rack can be adjusted while the other multifunctional slide racks are placed with slides or adjusted.

[0027] The beneficial effects of the present application compared with the prior art are:

[0028] The multifunctional slide rack provided by the present application is rotatably connected with the slide rack base through the heating table, the push rod pushes the heating table to overturn, which facilitates the diversion of reagents to the waste liquid collection platform; the long circular hole design of the limiting hole and the mounting hole enables the mounting position of the connecting plate and the rotating seat to be adjustable, improving the installation accuracy and convenience; at the same time, the slide rack base provides stable support for the heating table, the waist-shaped hole, the bushing and the shaft prevent assembly eccentricity and reduce wear caused by work; the heating table stud cooperates with the push rod tension spring, so that the heating table can be restored to position and cannot be completely reset after overturning, the sensor accurately judges whether a slide is placed in the slide groove by detecting the identification code, the heating table is designed in layers by using the floating assembly, which is convenient for adjusting the height and flatness of the heating table body, and further configures a heating vibration groove to optimize the experimental conditions; the dyeing assembly controls the displacement of the multifunctional slide rack by using the driving motor, the guide rail, the pulley and the synchronous belt, efficiently collects waste liquid, and each multifunctional slide rack can be independently controlled, and other slide racks can be operated during work, thereby comprehensively improving the work efficiency. BRIEF DESCRIPTION OF DRAWINGS

[0029] The accompanying drawings are included to provide a further understanding of embodiments and are incorporated in and constitute a part of this specification. The drawings illustrate embodiments and, together with the description, serve to explain the principles of the present application. Other embodiments and many of the intended advantages of the present application will be readily appreciated as the same becomes better understood by reference to the following detailed description. The elements of the drawings are not necessarily to scale. Like reference numerals designate corresponding similar parts throughout the various views.

[0030] Figure 1 is an exploded schematic view of a multifunctional slide rack according to an embodiment of the present application;

[0031] Figure 2 is another exploded schematic view of a multifunctional slide rack according to an embodiment of the present application;

[0032] Figure 3 is a schematic view of a left side plate mounting according to a specific embodiment of the present application;

[0033] Figure 4 is a schematic view of a push rod mounting according to a specific embodiment of the present application;

[0034] Figure 5 is an exploded schematic view of a heating platform according to a specific embodiment of the present application;

[0035] Figure 6 is a cross-sectional view of a multifunctional slide rack after assembly according to a specific embodiment of the present application;

[0036] Figure 7 is a schematic view of a staining assembly according to an embodiment of the present application.

[0037] Meaning of each number in the figure:

[0038] Slide rack base 01, heating platform 02, push rod 03, fixed end 04, output end 05, flow guide groove 06, bottom plate 07, front panel 08, rear cover plate 09, left side plate 10, right side plate 11, embedded groove 12, connecting plate 13, limiting hole 14, rotating shaft 15, waist-shaped hole 16, bushing 17, rotating seat 18, mounting hole 19, stud 20, push hole 21, tension spring 22, heating platform base 23, floating assembly 24, heating platform body 25, slide groove 26, glass slide 27, identification code 28, identification hole 29, sensor 30, stand 31, drainage groove 32, heating and vibrating groove 33, heating film 34, thermistor 35, vibrating assembly 36, assembly bottom plate 37, guide rail 38, pulley 39, drive motor 40, waste liquid collection platform 41. DETAILED DESCRIPTION

[0039] In the following detailed description, reference is made to the accompanying drawings, which form part of the detailed description and illustrate illustrative specific embodiments in which the present invention may be practiced. In this regard, directional terms such as “top,” “bottom,” “left,” “right,” “up,” “down,” etc., are used with reference to the orientation of the described figures. Because components of the embodiments can be positioned in several different orientations, directional terms are used for illustrative purposes and are by no means limiting. It should be understood that other embodiments may be utilized or logical changes may be made without departing from the scope of the present invention. Therefore, the following detailed description should not be taken in a limiting sense, and the scope of the present invention is defined by the appended claims.

[0040] According to the first aspect of this application, a multifunctional slide holder is proposed. Figure 1 An exploded view of a multifunctional slide holder according to an embodiment of this application is shown, as follows: Figure 1 As shown, the multifunctional slide holder includes a slide holder base 01 and a heating platform 02. The left and right outer sides of the heating platform 02 are rotatably connected to the top inner side of the slide holder base 01, and the front bottom edge of the heating platform 02 is in contact with the top surface of the slide holder base 01. A push rod 03 is provided inside the slide holder base 01. The fixed end 04 of the push rod 03 is rotatably connected to the inner bottom surface of the slide holder base 01, and the output end 05 of the push rod 03 is rotatably connected to the center of the front bottom surface of the heating platform 02. The push rod 03 is obliquely upward along the rear to the front of the heating platform 02. A guide groove 06 is obliquely downward at the rear of the slide holder base 01. The guide groove 06 is located below the heating platform 02 and extends to the rear of the slide holder base 01. The output end 05 pushes the front bottom surface of the heating platform 02 upward, causing the rear of the heating platform 02 to tilt towards the guide groove 06.

[0041] By adopting the above technical solution, the heating stage 02 is rotatably connected to the slide holder base 01. When the bottom surface of the heating stage 02 is parallel to the slide holder base 01, the front bottom edge of the heating stage 02 can be supported by the top surface of the slide holder base 01, and the push rod 03 can also provide stable support force to prevent the heating stage 02 from flipping. When the slide 27 is cleaned with reagent, the push rod 03 can push the heating stage 02 to flip, so that the rear of the heating stage 02 flips and tilts the guide channel 06 at a certain angle, so that the reagent can flow from the rear of the heating stage 02 into the guide channel 06, and then flow into the waste liquid collection platform 41 through the guide channel 06.

[0042] Figure 2 Another exploded view of a multifunctional slide holder according to an embodiment of this application is shown, as follows: Figures 1-2As shown, the slide holder base 01 includes a base plate 07, a front panel 08, a rear cover plate 09, a left side plate 10, and a right side plate 11. The front panel 08, the rear cover plate 09, the left side plate 10, and the right side plate 11 are respectively connected to the front, rear, left, and right edges of the base plate 07 and cooperate with each other to form a cavity for accommodating the push rod 03. The top of the cavity has an opening corresponding to the position of the heating stage 02.

[0043] Specifically, the top surface of the rear cover plate 09 is a slope, and the guide channel 06 is fixed to this slope by bolts.

[0044] By adopting the above technical solution, the front panel 08, rear cover plate 09, left side plate 10 and right side plate 11 cooperate with each other along the edge of the bottom plate 07 to form a cavity that can accommodate the push rod 03. An opening is provided at the top of the cavity so that the output end 05 of the push rod 03 can cooperate with the bottom surface of the heating table 02 from the opening position. At the same time, the front panel 08, rear cover plate 09, left side plate 10 and right side plate 11 cooperate with each other to form a complete top surface, and the front bottom surface of the heating table 02 can fit against the top surface.

[0045] Figure 3 A schematic diagram of the left side panel mounting according to a specific embodiment of this application is shown, as follows: Figures 1-3 As shown, the upper part of the outer side surface of the left side plate 10 and the right side plate 11 are provided with an embedding groove 12. A connecting plate 13 is installed in the embedding groove 12. The connecting plate 13 is connected to the hole of the embedding groove 12 through a limiting hole 14. The limiting hole 14 is an elongated hole that extends from both ends to the front panel 08 and the rear cover plate 09. The width of the embedding groove 12 is greater than the width of the connecting plate 13.

[0046] By adopting the above technical solution, an additional connecting plate 13 is provided to facilitate the cooperation between the slide holder base 01 and the heating stage 02. At the same time, the limiting hole 14 is designed as an elongated hole, which allows the position of the connecting plate 13 in the embedding groove 12 to be adjusted in the front and back direction, thereby improving the installation accuracy and facilitating installation.

[0047] More preferably, the top of the connecting plate 13 has a rotating shaft 15 passing through it, and the left and right outer sides of the heating table 02 are provided with corresponding waist-shaped holes 16. A bushing 17 is embedded in the waist-shaped hole 16, and the rotating shaft 15 is rotatably connected to the bushing 17.

[0048] Specifically, the left and right edges of the rear cover plate 09 are bent towards the left side plate 10 and the right side plate 11, respectively, and fit against the edges of the left side plate 10 and the right side plate 11. Meanwhile, in this embodiment, a part of the embedding groove 12 is formed on the rear cover plate 09. There is a notch at the top of the embedding groove 12. After the rotating shaft 15 passes through the connecting plate 13, it enters the cavity above the slide holder base 01 through the notch and then rotates with the bushing 17 in the waist-shaped hole 16. Since the limiting hole 14 is an elongated hole, screws are used to position the connecting plate 13 and the hole on the left side plate 10. Then the position of the connecting plate 13 is adjusted along the stroke range of the limiting hole 14. After the position is determined, the screws are locked. The relevant installation structure of the right side plate 11 is the same as above.

[0049] By adopting the above technical solution, the design of the waist-shaped hole 16, bushing 17 and rotating shaft 15 can prevent the left and right sides of the heating stage 02 from being misaligned with the glass slide holder base 01 during the assembly process. At the same time, it can reduce wear on the heating stage 02 in working environments where it is frequently rotated, and make it easier to install and replace.

[0050] Continue to refer to Figures 1-3 The upper rear surface of the base plate 07 is provided with a rotating seat 18. The bottom surface of the rotating seat 18 has a mounting hole 19 that is connected to the hole on the surface of the base plate 07. The mounting hole 19 is an elongated hole that extends to the front panel 08 and the rear cover plate 09 at both ends respectively. The fixed end 04 of the push rod 03 is rotatably connected to the rotating seat 18.

[0051] By adopting the above technical solution, the rotating seat 18 can have a certain adjustment space when it is engaged with the base plate 07. By adjusting the rotation position forward and backward, the installation position of the fixed end 04 of the push rod 03 can be changed, thus achieving adjustability.

[0052] Figure 4 A schematic diagram of the push rod installation according to a specific embodiment of this application is shown, such as... Figures 1-4 As shown, the front bottom surface of the heating platform 02 is vertically provided with symmetrical studs 20. The output end 05 of the push rod 03 is provided with push holes 21 on the left and right sides. The push holes 21 are provided with tension springs 22. The hooks of the tension springs 22 are fixed on the studs 20 on the left and right sides respectively.

[0053] Specifically, during the installation process, the fixed end 04 of the push rod 03 first engages with the rotating seat 18, and the push hole 21 of the output end 05 is fitted with a tension spring 22. The hooks at both ends of the tension spring 22 are then fixed to the studs 20 on the left and right sides with screws. At this time, by adjusting the position of the rotating seat 18 forward / backward along the stroke range of the mounting hole 19, the tension of the push rod 03 on the middle of the tension spring 22 can be adjusted, changing the preload of the tension spring 22 and increasing the force generated by the tension spring 22 during the resetting process of the heating table 02, so that the heating table 02 is completely reset.

[0054] By adopting the above technical solution, when the push rod 03 is installed, the position of the rotating seat 18 is adjusted backward, and the tension spring 22 is pulled backward. During the rotation of the heating platform 02, the output end 05 of the push rod 03 extends to different lengths, which can drive the heating platform 02 to rotate at different angles. The output end 05 of the push rod 03 pushes the heating platform 02 upward to make it rotate. When the heating platform 02 needs to be reset, under the elastic force of the tension spring 22, the heating platform 02 can accurately return to its position.

[0055] Figure 5 An exploded view of a heating table according to a specific embodiment of this application is shown, as follows: Figures 1-5 As shown, the heating stage 02 includes, from bottom to top, a heating stage base 23, a floating component 24, a heating stage body 25, and a glass slide 27. The end of the heating stage base 23 is connected to the heating stage body 25 through the floating component 24. The top surface of the heating stage body 25 has a slide groove 26 for placing the glass slide 27. The front end of the glass slide 27 has an identification code 28. The heating stage base 23 has an identification hole 29 corresponding to the identification code 28. A sensor 30 is installed below the identification hole 29.

[0056] By adopting the above technical solution, the heating stage base 23 is connected to the heating stage body 25 by means of the floating component 24. During the installation process, the height of the end point of the heating stage body 25 can be adjusted by means of the floating component 24, thereby avoiding the phenomenon that the upper surface of the heating stage body 25 is not level enough, causing the liquid to flow out of the slide 27. At the same time, the position of the identification code 28 on the slide 27 corresponds to the position of the identification hole 29. The sensor 30 can detect the identification code 28 through the identification hole 29 and determine whether the slide 27 is placed in the slide slot 26 by judging the identification code 28.

[0057] Specifically, sensor 30 can determine whether slide 27 is placed by directly detecting identification code 28 or by light detection. Furthermore, when using identification code 28, sensor 30 can be an optical sensor such as a QR code / barcode scanner or an RFID sensor. Even further, sensor 30 can be a diffuse reflection sensor. In this case, sensor 30 emits light onto slide 27 and generates diffuse reflection. Sensor 30 receives the diffusely reflected light and generates a corresponding electrical signal. When slide 27 is not placed, no corresponding electrical signal is generated, thereby detecting the placement status of slide 27. When sensor 30 is a diffuse reflection sensor, it does not need to cooperate with identification code 28.

[0058] More preferably, the slide groove 26 is provided with columns 31 at the rear end and on the left and right sides, and the columns 31 are provided close to the rear end face and the left and right sides of the slide 27; the slide groove 26 is provided with drainage channels 32 extending to the rear end and inclined on the left and right sides, the outlet of the drainage channel 32 is located above the guide channel 06, and the guide channel 06 is inclinedly installed on the top of the rear cover plate 09.

[0059] By adopting the above technical solution, the column 31 is set to prevent the slide 27 from falling out of the slide groove 26 during the staining process. At the same time, the inclined drainage groove 32 can drain excess reagent to the rear end of the slide groove 26, which can effectively prevent splashing and liquid accumulation.

[0060] Figure 6 A cross-sectional view of a multifunctional slide holder assembled according to a specific embodiment of this application is shown, as follows. Figures 1-6 As shown, a heating vibration groove 33 is provided on the bottom rear surface of the heating table body 25. A heating film 34 is attached to the top surface of the heating vibration groove 33. A thermistor 35 is provided on the heating film 34, and several vibration components 36 are provided below the heating film 34.

[0061] Specifically, the floating component 24 consists of four independent springs, and the two ends of the springs are flexibly engaged with the heating platform base 23 and the heating platform body 25 through connecting seats. The four ends of the heating platform base 23 are provided with four corresponding grooves. At the same time, the bottom surface of the heating platform body 25 is also provided with corresponding grooves. After engagement, there is a certain gap between the heating platform base 23 and the heating platform body 25. Furthermore, the position of the connecting seat at the bottom of the spring is adjustable, thereby adjusting the height of the floating component 24 to change the distance between the heating platform base 23 and the heating platform body 25. In addition, the floating component 24, in conjunction with the vibration component 36, can also improve the vibration mixing effect.

[0062] Furthermore, the heating film 34 is bonded to the heating vibration groove 33 with thermally conductive adhesive, which serves to conduct heat and provide insulation. In addition, the vibration assembly 36 consists of a motor base and a vibration motor. In this embodiment, there are two vibration assemblies 36. The vibration motor provides power to the heating stage 02, which drives the glass slide 27 to vibrate.

[0063] Specifically, a cavity can be opened inside the front panel 08 to house the PCB circuit board.

[0064] By adopting the above technical solution, the heating film 34 is used to heat the glass slide on the slide groove 26 from below. At the same time, the thermistor 35 can monitor the heating temperature in real time. Since different reaction reagents require different reaction temperatures, the temperature of the heating film 34 can be controlled by the thermistor 35 to improve the reaction effect of different reagents. The vibration component 36 below the heating film 34 can provide power to the heating stage body 25, thereby driving the glass slide 27 to vibrate, increasing the collision and binding efficiency of reagents with antibodies in the glass slide 27, and shortening the reaction time.

[0065] According to a second aspect of this application, a staining component is proposed. Figure 7 A schematic diagram of the structure of a dyeing assembly according to an embodiment of this application is shown, as follows. Figures 1-7 As shown, the staining assembly includes any of the multifunctional slide holders described above, as well as an assembly base plate 37 and several guide rails 38 parallel to the upper surface of the assembly base plate 37. One end of the guide rail 38 is provided with a pulley 39, and the other end of the guide rail 38 is provided with a drive motor 40. The drive motor 40 is connected to the pulley 39 via a synchronous belt (not shown in the figure), and the bottom surface of the slide holder base 01 is slidably disposed on the guide rail 38 and connected to the surface of the synchronous belt. It also includes a waste liquid collection platform 41, which is disposed at one end of the guide rail 38 and corresponds to the position of the guide channel 06.

[0066] Specifically, during the reagent cleaning process, the glass slide 27 is flipped with the heating stage 02, and the liquid flows into the waste liquid collection platform 41 through the guide channel 06. The liquid in the waste liquid collection platform 41 is then pumped to the external waste liquid tank by an additional pump.

[0067] By adopting the above technical solution, a separate drive motor 40 is used to independently control the multifunctional slide holder on each guide rail 38. The slide holder base 01 is driven to move back and forth along both ends of the guide rail 38 through the cooperation of the drive motor 40, pulley 39 and synchronous belt. When the slide holder base 01 is driven to one end close to the waste liquid collection platform 41, the guide channel 06 can cooperate with the waste liquid collection platform 41 to collect excess liquid. In addition, during the cell staining process, one multifunctional slide holder can place slides 27 on other multifunctional slide holders or make adjustments while one multifunctional slide holder is working.

[0068] The multifunctional slide holder proposed in this application, combined with the staining assembly, allows for individual control of each slide 27. The slides can be tilted for cleaning, resulting in a more thorough cleaning and less cleaning solution residue on the slides 27. A sensor 30 is also provided to monitor whether a slide is in place. The vibration assembly 36, in conjunction with the floating assembly 24, accelerates the mixing of reagents on the slides 27, reduces noise generated by vibration, and speeds up the reaction time. The heating film 34 controls the reaction temperature to accommodate the reaction temperatures required for different reagents.

[0069] Obviously, those skilled in the art can make various modifications and changes to the embodiments of this utility model without departing from the spirit and scope of this utility model. In this way, this utility model is also intended to cover such modifications and changes if they fall within the scope of the claims of this utility model and their equivalents. The word "comprising" does not exclude the presence of other elements or steps not listed in the claims. The simple fact that certain measures are described in mutually different dependent claims does not indicate that a combination of these measures cannot be used for profit. Any reference numerals in the claims should not be considered as limiting the scope.

Claims

1. A multifunctional slide holder, characterized in that, The device includes a slide holder base and a heating stage. The left and right outer sides of the heating stage are rotatably connected to the top inner side of the slide holder base, and the front bottom edge of the heating stage is in contact with the top surface of the slide holder base. A push rod is provided inside the slide holder base. The fixed end of the push rod is rotatably connected to the inner bottom surface of the slide holder base, and the output end of the push rod is rotatably connected to the center of the front bottom surface of the heating stage. The push rod is obliquely upward along the rear to the front of the heating stage. A guide groove is obliquely downward at the rear of the slide holder base. The guide groove is located below the heating stage and extends to the rear of the slide holder base. The output end pushes the front bottom surface of the heating stage upward, causing the rear of the heating stage to tilt towards the guide groove.

2. The multifunctional slide holder according to claim 1, characterized in that, The slide holder base includes a base plate, a front panel, a rear cover plate, a left side plate, and a right side plate. The front panel, rear cover plate, left side plate, and right side plate are respectively connected to the front, rear, left, and right edges of the base plate and cooperate with each other to form a cavity for accommodating the push rod. The top of the cavity has an opening corresponding to the position of the heating stage.

3. The multifunctional slide holder according to claim 2, characterized in that, The upper outer surface of both the left and right side panels is provided with an embedding groove, and a connecting plate is installed in the embedding groove. The connecting plate is connected to the hole of the embedding groove through a limiting hole. The limiting hole is an elongated hole that extends from both ends toward the front panel and the rear cover plate, and the width of the embedding groove is greater than the width of the connecting plate.

4. The multifunctional slide holder according to claim 3, characterized in that, A rotating shaft passes through the top of the connecting plate, and corresponding waist-shaped holes are provided on the left and right outer sides of the heating platform. A bushing is embedded in the waist-shaped hole, and the rotating shaft is rotatably connected to the bushing.

5. The multifunctional slide holder according to claim 2, characterized in that, The upper rear surface of the base plate is provided with a rotating seat. The bottom surface of the rotating seat has a mounting hole that connects to the hole on the surface of the base plate. The mounting hole is an elongated hole that extends at both ends toward the front panel and the rear cover plate, respectively. The fixed end of the push rod is rotatably connected to the rotating seat.

6. The multifunctional slide holder according to claim 5, characterized in that, The front bottom surface of the heating platform is vertically provided with symmetrical studs. The output end of the push rod is provided with push holes on the left and right sides. A tension spring is provided in the push hole, and the hook of the tension spring is fixed on the studs on the left and right sides respectively.

7. The multifunctional slide holder according to claim 2, characterized in that, The heating stage, from bottom to top, includes a heating stage base, a floating component, a heating stage body, and a glass slide. The end point of the heating stage base is connected to the heating stage body through the floating component. The top surface of the heating stage body has a slide slot for placing the glass slide. The front end of the glass slide has an identification code. The heating stage base has an identification hole corresponding to the position of the identification code. A sensor is installed below the identification hole.

8. The multifunctional slide holder according to claim 7, characterized in that, The slide groove is provided with columns at the rear end and on the left and right sides. The columns are set close to the rear end face and the left and right sides of the slide. The left and right sides of the rear part of the slide groove are provided with drainage channels that extend towards the rear end and are inclined. The outlet of the drainage channel is located above the drainage channel, and the drainage channel is inclinedly installed on the top of the rear cover plate.

9. The multifunctional slide holder according to claim 7, characterized in that, The rear bottom surface of the heating platform body is provided with a heating vibration groove, the top surface of the heating vibration groove is covered with a heating film, the heating film is provided with a thermistor, and several vibration components are provided below the heating film.

10. A staining assembly comprising a multifunctional slide holder as described in any one of claims 1-9, characterized in that, It also includes a component base plate and several guide rails arranged parallel to the upper surface of the component base plate. One end of the guide rail is provided with a pulley, and the other end of the guide rail is provided with a drive motor. The drive motor is connected to the pulley through a synchronous belt, and the bottom surface of the slide holder base is slidably disposed on the guide rail and connected to the surface of the synchronous belt. It also includes a waste liquid collection platform, which is disposed at one end of the guide rail and corresponds to the position of the guide channel.

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