Hydrogel burst strength testing device and system

Abstract

The utility model relates to a hydrogel burst strength testing device and system, and belongs to the technical field of gel testing. The testing device comprises a pressing plate and a base. A sealing ring is installed on the face, facing the base, of the pressing plate, a template and a substrate are sequentially arranged between the sealing ring and the base, holes are formed in the pressing plate, the template and the substrate respectively to form a through hole channel, the hole channel is communicated with the blind hole of the base, and a through opening is formed in the side wall of the blind hole. The sizes of holes in the pressing plate, the template and the substrate are sequentially reduced, and the size of the hole in the substrate is smaller than the diameter of the blind hole; the pressing plate and the base are fixed through a plurality of hanging ring fixing bolts. According to the testing device, the base, the template and the holes are concentrically arranged, and the small holes are formed in the position of the base, so that the hydrogel can be completely formed without leakage, and the plugging requirement of a test can be met. The test main body can be assembled by installing a plurality of hanging ring fixing bolts, so that the fastening pressure is convenient to adjust, and the rapid test is convenient.

Description

Technical Field

[0001] This invention belongs to the field of gel testing technology, specifically relating to a testing device and system for the burst strength of hydrogels. Background Technology

[0002] Hydrogels, as biocompatible materials, are mainly used in medicine for postoperative anti-adhesion, hemostasis, filling of tissue defects, preventing tissue fluid leakage, and sustained drug release. Tissue adhesives have potential advantages over traditional suturing techniques, but some limitations remain. Currently, various hydrogels have been developed for wound repair. Their application in clinical surgery can not only reduce the use of sutures and postoperative anastomotic leakage, but also significantly shorten surgical time.

[0003] However, long-term practice has shown that hydrogel adhesives still have problems such as slow adhesion speed and easy water absorption, which leads to a decline in mechanical properties and inability to match tissues. Therefore, accurate measurement of the mechanical burst strength and other properties of hydrogels is of great significance for the clinical use of hydrogel adhesives. Utility Model Content

[0004] In view of the current state of technology, the purpose of this utility model is to provide a testing device and system for hydrogel burst strength, which is used to accurately measure the mechanical burst strength of hydrogel.

[0005] To achieve the above objectives, the technical solution of this utility model is as follows:

[0006] In a first aspect, a testing device for the burst strength of hydrogels includes a pressure plate and a base;

[0007] A sealing ring is installed on the side of the pressure plate facing the base. A template and a base are arranged sequentially between the sealing ring and the base. Holes are provided on the pressure plate, template, and base to form a through channel. The channel connects to a blind hole in the base. A through opening is provided on the side wall of the blind hole. The hole size on the pressure plate, template, and base decreases sequentially, and the hole size on the base is smaller than the diameter of the blind hole.

[0008] The pressure plate and the base are fixed together by a plurality of lifting eye bolts. A fixing pin passes through the lifting eye of the lifting eye bolt and is limited to the base. The threaded part of the lifting eye bolt is connected to a nut, which is located on the side of the pressure plate away from the base.

[0009] Optionally, the holes on the template and the substrate are concentric.

[0010] Optionally, the pressure plate and the base are respectively provided with multiple lateral grooves, which are used to install lifting ring fixing bolts.

[0011] Optionally, the fixing pin is located on the side of the base away from the pressure plate in the lateral groove, the length direction of the fixing pin is parallel to the width direction of the lateral groove, and the width of the lateral groove is less than the length of the fixing pin.

[0012] Optionally, the base has through mounting holes for fixing pins on the opposite sidewalls of the lateral groove.

[0013] Optionally, the outer diameter of the nut is larger than the width of the lateral groove of the pressure plate.

[0014] Optionally, the nut is a wing nut.

[0015] Optionally, the substrate is made of animal-derived membrane tissue, including casings or collagen casings.

[0016] Secondly, a hydrogel burst strength testing system includes a pressurizing device, a pressure display device, and the aforementioned hydrogel burst strength testing device, wherein the pressurizing device and the pressure display device are respectively connected to the side wall opening of the blind hole.

[0017] Optionally, a safety switch is provided between the pressurization device and the hydrogel burst strength testing device.

[0018] Optionally, the pressurizing device includes an injection pump, a force application platform, a push rod, and a syringe connected in sequence, wherein the syringe is connected to the side wall opening of the blind hole of the testing device through a pipeline.

[0019] Optionally, the pressure display device is a pressure gauge.

[0020] The beneficial effects of this utility model are as follows:

[0021] This invention's testing device employs a concentric arrangement of the substrate, template, and holes. Small holes in the substrate ensure complete hydrogel formation without leakage, while also meeting the sealing requirements of the test. The template's holes are larger than those in the substrate, facilitating hydrogel formation within the template's space and simplifying testing. The main body of the testing device uses a quick-connect design, allowing for assembly via multiple lifting eyelets and fixing bolts, facilitating easy adjustment of tightening pressure and rapid testing. The device utilizes an injection pump for stable injection, reducing the impact of pulsation during testing and resulting in more accurate test results. Attached Figure Description

[0022] The accompanying drawings, which form part of this specification, are used to provide a further understanding of this utility model. The illustrative embodiments of this utility model and their descriptions are used to explain this utility model and do not constitute an improper limitation of this utility model.

[0023] Figure 1 This is a schematic diagram of the exploded structure of the test device in Example 1.

[0024] Figure 2 This is a cross-sectional structural diagram of the test device in Example 1.

[0025] Figure 3 This is a schematic diagram of the assembly structure of the test device in Example 1.

[0026] Figure 4 This is an isometric view of the assembled test apparatus in Example 1.

[0027] Figure 5 This is the assembly drawing of the test system in Example 2.

[0028] The components include: 1. Pressurizing device; 2. Safety switch; 3. Testing device; 4. Syringe; 401. Push rod; 5. Pressure display device; 6. T-joint; 7. Straight connector; 8. Connecting pipe; 101. Force application platform; 301. Base; 302. Pressure plate; 303. Wing nut; 304. Sealing ring; 305. Template; 306. Base; 307. Lifting eye bolt; 308. Fixing pin; 309. Hydrogel. Detailed Implementation

[0029] Example 1

[0030] A device for testing the burst strength of hydrogels, such as Figure 1 As shown, it includes a pressure plate 302 and a base 301;

[0031] A sealing ring 304 is installed on the side of the pressure plate 302 facing the base 301. A template 305 and a base 306 are sequentially arranged between the sealing ring 304 and the base 301. Holes are provided on the pressure plate 302, template 305, and base 306 to form a through channel. Figure 2 As shown, the channel connects to the blind hole of the base 301, and the side wall of the blind hole is provided with a through opening; the hole sizes on the pressure plate 302, template 305 and base 306 decrease in sequence, and the hole size of the base 306 is smaller than the diameter of the blind hole of the base 301.

[0032] like Figure 2 As shown, the sealing ring 304 is installed in the slot of the pressure plate 302 to press the template 305 and the base 306.

[0033] The template 305 has a thickness of 1 mm and an opening diameter of 15 mm. The opening is used for the molding of hydrogel 309. The base 306 has an opening diameter of no more than 3 mm, which is used to transfer the liquid pressure in the blind hole to the hydrogel 309.

[0034] The holes on the template 305 and the substrate 306 are concentric, so that the pressure-bearing position of the hydrogel 309 on the template 305 is located at the center of the hydrogel membrane. Since the hydrogel 309 is fixed around the perimeter, the stress situation of the membrane hydrogel 309 is centrally symmetrical, which reduces the measurement deviation caused by the shape and makes the measurement results more accurate.

[0035] like Figure 2 As shown, the pressure plate 302 and the base 301 are fixed together by four eye bolts 307. A fixing pin 308 passes through the eye of the eye bolt 307. The fixing pin 308 is located on the base 301. The threaded part of the eye bolt 307 is connected to a wing nut 303. The wing nut 303 is located on the side of the pressure plate away from the base.

[0036] The pressure plate 302 and the base 301 are each provided with 4 side grooves, and the side grooves on the pressure plate 302 and the base 301 are connected to form a straight groove. The side grooves are used to install the lifting eye fixing bolts 307.

[0037] The fixing pin 308 is located on the side of the lateral groove of the base 301 away from the pressure plate 302. The length direction of the fixing pin 308 is parallel to the width direction of the lateral groove, and the width of the lateral groove is less than the length of the fixing pin 308, so that the fixing pin 308 cannot move in the length direction of the lateral groove, thereby achieving the limiting function.

[0038] The side wall opposite to the side groove of the base 301 is provided with a through fixing pin mounting hole. When the lifting eye of the lifting eye fixing bolt 307 is inserted into the side groove of the base 301, the fixing pin 308 can be inserted through the fixing pin mounting hole, which facilitates installation.

[0039] The outer diameter of the wing nut 303 is larger than the width of the side groove of the pressure plate 302, so that the wing nut 303 and the fixing pin 308 clamp the base 301 and the pressure plate 302 from two directions, thereby causing the sealing ring 304 to squeeze the template 305 and the base 306, thus achieving the sealing of the upper opening of the blind hole. Therefore, the liquid pressure in the blind hole is the pressure bearing capacity of the hydrogel 309 in the template, and the burst strength of the hydrogel 309 can be evaluated by measuring the liquid pressure in the blind hole.

[0040] When installing the hydrogel burst strength testing device in this embodiment, as follows: Figure 3 As shown, firstly, a template 305 is placed on the substrate 306. Then, hydrogel 309 is injected into the holes of the template 305, filling the through holes of the template and sealing the holes of the substrate 306 to form a hydrogel test piece. The hydrogel test piece is then installed above the blind hole of the base 301. Next, a lifting eye fixing bolt 307 is installed in the lateral groove of the pressure plate 302 and the base 301, and a fixing pin 308 is used to limit the position of the lifting eye fixing bolt 307 relative to the base 301. Then, as... Figure 4As shown, a pressure plate 302 with a sealing ring 304 is installed on it. A wing nut 303 is installed on the upper side of the pressure plate 302, and the pressure of the sealing ring 304 is adjusted by turning the wing nut 303.

[0041] The base 306 is made of sausage casing with a thickness of 0.1-0.5 mm and a diameter larger than the outer diameter of the template 305. The sausage casing has strong elasticity and can maintain good toughness without breaking under high water pressure. Furthermore, its thin thickness allows it to transmit pressure well, mimicking the application scenario of wound repair. The templates 305 and the base 301 on both sides of the base are made of rigid materials, thus achieving a seal between the base 306 and the template 305, and between the base 306 and the base 301, under the pressure of the pressure plate 302.

[0042] Example 2

[0043] A testing system for the burst strength of hydrogels, such as Figure 5 As shown, the device includes a pressurizing device 1, a pressure display device 5, and the aforementioned hydrogel burst strength testing device 3. The pressurizing device 1 and the pressure display device 5 are respectively connected to the side wall opening of the blind hole of the testing device 3.

[0044] Specifically, a straight connector 7 is installed in the side wall opening of the blind hole of the testing device 3. The straight connector 7 is connected to a tee 6 through a connecting pipe 8. The other two ports of the tee 6 are connected to the pressurizing device 1 and the pressure display device 5 through the connecting pipe 8, respectively.

[0045] A safety switch 2 is installed between the pressurizing device 1 and the hydrogel burst strength testing device 3 to prevent the test liquid in the testing device 3 from flowing back after the power of the pressurizing device 1 is turned off during the test, so that the pressure during the test is maintained at the set value.

[0046] The pressurizing device 1 includes an injection pump, a force application platform 101, and a syringe 4 connected in sequence. The syringe 4 is connected to the side wall opening of the blind hole of the test device 3 through a connecting pipe 8. The syringe 4 contains a set amount of purified water. The injection pump is connected to the force application platform 101. The force application platform 101 can push the plunger 401 of the syringe 4 to move forward at a constant speed without pulse. The pushing rate of the injection pump is adjustable from 0.1 to 1600 mL / h.

[0047] The pressure display device 5 is a pressure gauge that can display the peak pressure in real time, which is convenient for test recording.

[0048] The testing process of the hydrogel burst strength testing system in this embodiment includes:

[0049] Connect the pipeline, turn on safety switch 2, turn on the injection pump, and fill the base 301 with pure water to eliminate the air in the connecting pipe 8 and the cavity of the base 301.

[0050] Turn off the injection pump, install the hydrogel test piece from Example 1 above the blind hole of the base 301 and eliminate the gas under the hydrogel test piece, and continue to fix and tighten it with the eye bolt 307 and wing nut 303 as in Example 1.

[0051] Set the pressure display device 5 to zero and set it to capture peak pressure.

[0052] Turn on the injection pump in pressurization device 1 again. Different flow rates can be set according to the test requirements. The pressure gauge captures different peak pressures to test whether the hydrogel meets the required peak pressure.

[0053] During the above process, the peak pressure of the pressure gauge is the bursting strength of the hydrogel.

[0054] The substrate 306 is an elastic material used to simulate biological tissue during wound repair. The pores on the substrate 306 are used to simulate wounds. Pure water in the test device 3 applies pressure to the hydrogel 309 through the pores of the substrate 306, which can test the burst strength of the hydrogel 309 material itself. The deformation state of the substrate 306 itself during the test is also close to the actual state of wound repair, making the test results closer to the effect of actual clinical application.

[0055] The above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Various modifications and variations can be made to this utility model by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A device for testing the burst strength of hydrogels, characterized in that, The device includes a pressure plate and a base. A sealing ring is installed on the side of the pressure plate facing the base. A template and a base are sequentially arranged between the sealing ring and the base. Holes are provided on the pressure plate, template, and base to form a through channel. The channel connects to a blind hole in the base. The sidewall of the blind hole has a through opening. The hole sizes on the pressure plate, template, and base decrease sequentially, and the hole size on the base is smaller than the diameter of the blind hole. The pressure plate and the base are fixed together by multiple lifting eye bolts. A fixing pin passes through the lifting eye of each lifting eye bolt. The fixing pin is located on the base. The threaded part of the lifting eye bolt is connected to a nut. The nut is located on the side of the pressure plate away from the base.

2. The testing apparatus for the burst strength of hydrogels as described in claim 1, characterized in that, The holes on the template and the substrate are concentric.

3. The testing apparatus for the burst strength of hydrogels as described in claim 1, characterized in that, The pressure plate and the base are respectively provided with multiple side grooves, which are used to install lifting ring fixing bolts.

4. The testing apparatus for the burst strength of hydrogels as described in claim 3, characterized in that, The fixing pin is located on the side of the base away from the pressure plate in the side groove. The length direction of the fixing pin is parallel to the width direction of the side groove, and the width of the side groove is less than the length of the fixing pin.

5. The testing apparatus for the burst strength of hydrogels as described in claim 3, characterized in that, The base has through mounting holes for fixing pins on the opposite side walls of the side groove.

6. The testing apparatus for the burst strength of hydrogels as described in claim 1, characterized in that, The substrate is made of animal-derived thin film tissue.

7. A testing system for the burst strength of hydrogels, characterized in that, It includes a pressurizing device, a pressure display device, and a test device for the burst strength of hydrogel as described in any one of claims 1-6, wherein the pressurizing device and the pressure display device are respectively connected to the side wall opening of the blind hole.

8. The hydrogel burst strength testing system as described in claim 7, characterized in that, A safety switch is provided between the pressurization device and the hydrogel burst strength testing device.

9. The hydrogel burst strength testing system as described in claim 7, characterized in that, The pressurization device includes an injection pump, a force application platform, a push rod, and a syringe connected in sequence. The syringe is connected to the side wall opening of the blind hole of the test device through a pipeline.

10. The hydrogel burst strength testing system as described in claim 7, characterized in that, The pressure display device is a pressure gauge.

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