Chromatographic column box

Abstract

The utility model relates to a chromatographic technology, and particularly provides a chromatographic column box which comprises a box body, a TEC (Thermoelectric Cooler) and a temperature sensor, and a chromatographic column is fixed in the box body; the box body comprises a lower cover, a hollow cavity and an upper cover, the lower cover and the upper cover are fixed on the lower side and the upper side of the hollow cavity and are sealed, the TEC is fixed on the upper cover, and the temperature sensor is arranged in the cavity; the chromatographic column box further comprises a plurality of stand columns which are fixed on the inner wall of the lower cover, grooves or holes allowing the chromatographic columns to pass through are formed in the end portions of the stand columns, and the chromatographic columns are fixed in the grooves or the holes through fixing bands. The temperature control device has the advantages of high temperature control precision and the like.

Description

Technical Field

[0001] This utility model relates to chromatography technology, and in particular to chromatography column ovens. Background Technology

[0002] With increasing attention being paid to the hazards of atmospheric photochemical smog, real-time online monitoring of peroxyacyl nitrates (PANs), an important indicator of photochemical smog, has become a research hotspot. Currently, the components of PANs that can be monitored include PAN and PPN. The instrument principle is based on chromatographic separation, where PAN and PPN are separated by a chromatographic column and then detected by an electron capture detector (ECD). However, PAN and PPN are thermally unstable and easily decompose at high temperatures. Therefore, in order to ensure accurate and stable separation and detection of PAN and PPN, low-temperature control of the chromatographic column is required.

[0003] A commonly used column oven module includes an aluminum cooling rod with a TEC (Cooling Device) mount. A TEC cooling chip is mounted on the upper flat surface of the cooling rod, with the cold side facing down. The TEC cools the metal cooling rod to a specific low temperature. Double-sided tape is attached to the curved surface of the cooling rod to secure the quartz column. A temperature sensor is also attached to the curved surface of the cooling rod. Temperature control of the quartz column is achieved through thermal conduction within the metal cooling rod. The drawback of this approach is:

[0004] 1. The quartz chromatography column needs to be evenly attached to the cold core curved surface. This operation is very easy to break the quartz chromatography column, resulting in high production costs and low yield.

[0005] 2. The chromatographic column itself has a certain degree of toughness, and the double-sided adhesive is easy to fall off. It can also cause uneven cooling temperature, resulting in reduced instrument measurement accuracy and poor stability.

[0006] 3. To ensure airtightness, the circular outlet (through which the temperature sensor wire passes) needs to be sealed with glue, making disassembly and assembly inconvenient.

[0007] 4. The entire column oven is made of aluminum, which has good thermal conductivity but also makes it prone to condensation on the outer wall. Therefore, both the outer shell and the interior are filled with insulation cotton for heat preservation. This process is complicated and affects the aesthetics. After a long time, condensation will still be generated at the outlet of the column oven module. Utility Model Content

[0008] To address the shortcomings of the existing technical solutions, this utility model provides a chromatography column oven.

[0009] The objective of this utility model is achieved through the following technical solution:

[0010] A chromatography column oven includes a chamber, a TEC (Technical Equipment for Chromatography), and a temperature sensor, wherein the chromatography column is fixed within the chamber. The chamber includes a lower cover, a hollow cavity, and a upper cover. The lower cover and upper cover are fixed to and sealed to the lower and upper sides of the hollow cavity, respectively. The TEC is fixed to the upper cover, and the temperature sensor is disposed within the cavity. The chromatography column oven further includes:

[0011] The column and fixing strap are provided. Multiple columns are fixed to the inner wall of the lower cover and have grooves or holes at their ends that allow the chromatographic column to pass through. The fixing strap fixes the chromatographic column in the grooves or holes.

[0012] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0013] 1. By combining TEC and radiator fan, air-cooled diffusion technology is realized to replace metal cold core conduction technology. The internal cavity temperature of the column box module is more uniform, improving the TEC cooling efficiency and heat conduction efficiency.

[0014] A temperature sensor is fixed inside the chamber to test the air temperature. Combined with air cooling circulation, the column temperature is fed back more accurately. Combined with PID temperature control, the temperature control accuracy of the column oven is improved.

[0015] 2. The structure of the quartz chromatography column is optimized to prevent damage to the quartz chromatography column during installation;

[0016] 3. The entire column oven module is made of ABS plastic, which is more heat-insulating and aesthetically pleasing than the original metal material, while also preventing the generation of condensate. The column oven module is designed with a dedicated column outlet, which further ensures the sealing of the column module and prevents the generation of condensate. Attached Figure Description

[0017] The disclosure of this utility model will become more readily understood with reference to the accompanying drawings. It will be readily understood by those skilled in the art that these drawings are merely illustrative of the technical solutions of this utility model and are not intended to limit the scope of protection of this utility model. In the drawings:

[0018] Figure 1 This is a schematic diagram of the structure of the chromatography column oven according to this utility model;

[0019] Figure 2 This is based on a partial structural schematic diagram of the present invention;

[0020] Figure 3 This is a structural schematic diagram of the chromatography column oven interface according to this utility model.

[0021] In the attached diagram, 11-top cover, 12-cavity, 13-bottom cover, 14-pillar, 15-sealing ring, 21-TEC, 22-heat sink, 23-fan, 30-interface, 31-mounting base, 32-sleeve, 33-connector, 34-screw. Detailed Implementation

[0022] Figures 1-3 The following description illustrates optional embodiments of the present invention to teach those skilled in the art how to implement and reproduce it. For the purpose of teaching the technical solutions of the present invention, some conventional aspects have been simplified or omitted. Those skilled in the art should understand that variations or substitutions derived from these embodiments will be within the scope of the present invention. Those skilled in the art should understand that the following features can be combined in various ways to form multiple variations of the present invention. Therefore, the present invention is not limited to the following optional embodiments, but is defined only by the claims and their equivalents.

[0023] Example 1

[0024] One type of chromatographic column oven in this embodiment, such as Figure 1 The chromatography column oven includes:

[0025] The chromatographic column, chamber, TEC21, and temperature sensor are included. The chamber includes a lower cover 13, a hollow cavity 12, and an upper cover 11. The lower cover 13 and the upper cover 11 are fixed to the lower and upper sides of the hollow cavity 12 and sealed by connecting parts such as screws 34. The TEC21 is fixed to the upper cover 11, and the temperature sensor is disposed inside the cavity 12.

[0026] Multiple columns 14 are fixed on the inner wall of the lower cover 13, and the ends have grooves or holes that allow the chromatographic columns to pass through. Fixing straps fix the chromatographic columns in the grooves or holes.

[0027] To further improve temperature control efficiency and accuracy, such as... Figure 2 As shown, the chromatography column oven further includes:

[0028] The heat sink 22 and the fan 23 are fixed to the lower side of the heat sink 22. The heat sink 22 is fixed to the upper cover 11 by screws 34 and other connectors. The TEC 21 is connected to the heat sink 22, such as a toothed plate.

[0029] To further improve temperature control accuracy, the insulation layer is fixed to the inner walls of the upper cover 11, the cavity 12, and the lower cover 13.

[0030] To prevent condensation, further, such as Figure 3 As shown, the chromatography column oven also includes two interfaces 30, each interface 30 comprising:

[0031] Mounting base 31 is fixed on the outer wall of cavity 12.

[0032] The connector 33 is fixed on the mounting base 31, and the two ends of the chromatographic column are respectively connected to the connector 33.

[0033] The sleeve 32 is fixed on the mounting base 31, and the sleeve 32 is sealed to the mounting base 31 and the connector 33 respectively.

[0034] To better retain heat, the upper cover 11, cavity 12 and lower cover 13 are made of ABS plastic.

[0035] Example 2

[0036] Application example of the chromatography column oven according to Embodiment 1 of this utility model.

[0037] In this application example, such as Figure 1 As shown, the box includes an upper cover 11, a cavity 12, and a lower cover 13. The cavity 12 is a hollow cylinder. The upper cover 11, cavity 12, and lower cover 13 are all made of ABS plastic, and the inside of each is lined with 9mm thick insulation cotton. The upper cover 11 and cavity 12, as well as the lower cover 13 and the middle cavity 12, are sealed by O-rings 15.

[0038] Multiple columns 14 are fixed on the inner wall of the lower cover 13 and are on the same circumference. The upper end of the column 14 has a groove, through which the cable tie passes. After the inner wall of the cavity 12 is lined with insulation cotton, the cavity 12 and the lower cover 13 are locked together with screws 34. The chromatographic column is pre-wound with a diameter of 100mm and placed in the cavity 12. It is fixed in place by the cable tie on the column 14 (it does not need to move). Then, the upper cover 11 is installed on the cavity 12 using screws 34.

[0039] like Figure 2 As shown, after the metal heat sink 22 and fan 23 are fixed into a combination with screws 34, they are inserted into the pre-reserved opening of the top cover 11 and fixed with screws 34. A sealing ring 15 is provided between the heat sink 22 and the inner wall of the top cover 11. The TEC 21, heat sink 22 and fan 23 are arranged from top to bottom.

[0040] like Figure 3 As shown, two dedicated interfaces 30 are designed on the cavity 12 for installing the gas inlet and outlet of the chromatography column. The interfaces 30 are connected to the inside and outside of the chromatography column by a through-plate connector 33. A sealing sleeve 32 is installed around the through-plate connector 33 for heat insulation and to prevent condensation. The connector 33 is fixed to the sleeve 32 by screws 34. The sleeve 32 and the mounting base 31 are sealed by a sealing ring 15, and the connector 33 and the sleeve 32 are also sealed by a sealing ring 15.

[0041] Example 3

[0042] The application example of the chromatographic column oven in Embodiment 1 of this utility model differs from that in Embodiment 2 in that:

[0043] The top of the column 14 has a through hole through which the chromatographic column passes to achieve the purpose of fixation.

Claims

1. A chromatographic column oven, comprising a chromatographic column, an oven body, a TEC (thermal energy storage device), and a temperature sensor, wherein the chromatographic column is fixed within the oven body; characterized in that, The chamber includes a lower cover, a hollow cavity, and an upper cover. The lower cover and upper cover are fixed to and sealed on the lower and upper sides of the hollow cavity, respectively. The TEC is fixed to the upper cover, and the temperature sensor is disposed within the cavity. The column oven also includes: The column and fixing strap are provided. Multiple columns are fixed to the inner wall of the lower cover and have grooves or holes at their ends that allow the chromatographic column to pass through. The fixing strap fixes the chromatographic column in the grooves or holes.

2. The column oven according to claim 1, characterized in that, The column oven also includes: A radiator and a fan, wherein the fan is fixed to the underside of the radiator, the radiator is fixed to the top cover, and the TEC is connected to the radiator.

3. The column oven according to claim 2, characterized in that, The radiator is a toothed plate.

4. The column oven according to claim 2, characterized in that, The upper cover and the cavity are connected by screws, as are the lower cover and the cavity, and the radiator and the upper cover.

5. The column oven according to claim 1, characterized in that, The column oven also includes: The insulation layer is fixed to the inner walls of the upper cover, cavity and lower cover.

6. The column oven according to claim 1, characterized in that, The column oven also includes two interfaces, the interfaces being: Mounting base, the mounting base being fixed to the outer wall of the cavity; A connector is fixed on the mounting base, and both ends of the chromatographic column are respectively connected to the connector; A sleeve is fixed on the mounting base, and the sleeve is sealed to the mounting base and the connector respectively.

7. The column oven according to claim 1, characterized in that, The upper cover, cavity, and lower cover are all made of ABS plastic.

8. The column oven according to claim 1, characterized in that, The cavity is hollow cylindrical inside, with O-rings placed between the upper cover and the cavity, and between the lower cover and the cavity.

9. The column oven according to claim 1, characterized in that, Multiple columns are set on the same circumference.

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