Test tube cooling device

Abstract

The utility model discloses a test tube cooling device, which relates to the technical field of laboratories and medical instruments and comprises a support, a test tube fixing mechanism, an adjusting air bag, an air guide tube and an inflating component. The test tube fixing mechanism is mounted on the bracket and is used for fixedly connecting the test tube with the bracket. And the adjusting air bag is immersed in the cooling medium during use. One end of the air-guide tube communicates with the adjusting airbag. The inflation assembly communicates with the end, away from the adjusting air bag, of the air guide pipe and is used for inflating or deflating the adjusting air bag through the air guide pipe so as to adjust the size of the adjusting air bag, and therefore the liquid level height of the cooling medium is adjusted. By adopting the device, the ice-water mixture can better wrap the test tube, and the cooling is more lasting. The liquid level of the cooling medium can be adjusted by controlling the size of the adjusting air bag, and the cooling effect is guaranteed.

Description

Technical Field

[0001] This utility model relates to the field of laboratory and medical device technology, and in particular to a test tube cooling device. Background Technology

[0002] In routine laboratory and medical testing, ultrasonic disruptors are frequently used to break down tissues and cells to extract proteins, enzymes, and other substances. However, the ultrasonic probe generates heat during operation, which can affect the stability of in vitro biological organic molecules and even degrade them. This can lead to deviations in subsequent experimental results, such as protein content determination, and may even result in false negatives or false positives. Currently, some laboratory personnel typically immerse test tubes in ice water to cool them down during ultrasonic disruption.

[0003] Chinese Patent Application No. 201310622227.5 discloses an ultrasonic crushing cup for holding samples during ultrasonic crushing, comprising an ice cylinder containing a cooling medium and an inner crushing cup for holding the sample, as well as an outer lid screwed to the ice cylinder and an upper lid screwed to the outer lid. In this invention, the ice cylinder provides a low temperature for the sample in the inner crushing cup; due to the outer lid, the mist or foam generated by the sample in the inner crushing cup during ultrasonication is less likely to diffuse into the environment, preventing environmental harm.

[0004] Regarding the aforementioned technologies, when using this ultrasonic crushing cup, as the ice in the ice bucket that is in direct contact with the inner crushing cup gradually melts during operation, the ice layer height decreases, the heat dissipation area in direct contact with the inner crushing cup gradually decreases, the envelopment of the test tube is poor, and the cooling effect is reduced. Utility Model Content

[0005] To address the aforementioned technical problems, this utility model provides a test tube cooling device, comprising: a support, a test tube fixing mechanism, an adjusting air bladder, a gas guide tube, and an inflation assembly. The test tube fixing mechanism is mounted on the support and is used to fix the test tube to the support. The adjusting air bladder is immersed in the cooling medium during use, and one end of the gas guide tube is connected to the adjusting air bladder. The inflation assembly is connected to the end of the gas guide tube away from the adjusting air bladder, and is used to inflate or deflate the adjusting air bladder through the gas guide tube to adjust the volume of the adjusting air bladder, thereby adjusting the liquid level of the cooling medium.

[0006] To achieve the above objectives, this utility model is implemented through the following technical solution:

[0007] When using this test tube cooling device, add an appropriate amount of cooling medium (ice-water mixture) to the beaker, immerse the regulating bladder in the cooling medium, fix the test tube on the test tube fixing device, and adjust the position of the test tube in the cooling medium. Add the test sample to the test tube, and then start the ultrasonic disruptor. The ultrasonic probe of the ultrasonic disruptor will work in the test tube. When the ice in the ice-water mixture melts, causing the liquid level to drop, gas is injected into the regulating bladder through the inflation component to adjust the volume of the regulating bladder, thereby restoring the liquid level of the ice-water mixture in the beaker to the predetermined height. The cooling medium can continuously surround the test tube, cooling the ultrasonic probe. When it is observed that the ice in the beaker has mostly melted and the cooling effect decreases, the gas in the inflation component is sucked out of the inflation bladder, reducing the volume of the regulating bladder and creating more space in the beaker for adding ice, restoring the cooling medium to the state of an ice-water mixture. If the liquid level in the beaker is too high, water can be poured directly from the beaker for ice replenishment without disassembling the device.

[0008] Compared with the prior art, this utility model has the following advantages: the size of the airbag can be controlled and adjusted to regulate the liquid level of the cooling medium (ice-water mixture); the ice-water mixture has better envelopment of the test tube and better cooling persistence, ensuring the cooling effect; when the liquid level in the beaker is too high, the beaker can be tilted to pour the water directly out of the beaker without disassembling the device, making it convenient to use.

[0009] A further preferred embodiment is that the surface of the airbag is wrinkled when it contracts.

[0010] When the above technical solution is adopted, the volume change between the contraction and expansion of the regulating airbag is large, thereby expanding the range of adjustable liquid level.

[0011] A further preferred embodiment includes a first fixed arm and a second fixed arm disposed opposite to each other, with one end of the first fixed arm and the second fixed arm fixedly connected together, forming an acute angle between them. In use, it is fitted onto the side wall of a beaker containing the cooling medium.

[0012] When the above technical solution is adopted, the bracket is fixed at the opening of the beaker containing the cooling medium, and the test tube is stable in the position of the cooling medium, not easily moved, and has better stability.

[0013] More preferably, the test tube fixing mechanism includes:

[0014] Through hole, penetrating the support.

[0015] A fixed rod passes through a through hole and is slidably connected to the bracket, with the sliding direction along the length of the fixed rod.

[0016] A semi-ring is set at one end of the bracket, with its concave side corresponding to the end of the fixing rod.

[0017] The elastic element, with one end connected to the fixed rod and the other end connected to the bracket, is used to apply force to the fixed rod so that the fixed rod moves toward the semi-ring, thereby clamping and fixing the test tube between the semi-ring and the fixed rod.

[0018] When using the above technical solution, the fixing rod is manually pulled to create a space between the fixing rod and the semi-ring. The test tube is placed in the space, and then the fixing rod is released. Due to the interaction between the fixing rod and the semi-ring, as well as the clamping effect of the elastic element, the fixing rod and the semi-ring hold the test tube tightly, thereby fixing the test tube. The operation is convenient.

[0019] A further preferred embodiment is that a locking block is provided at one end of the fixing rod corresponding to the semi-ring, and an anti-slip pad is provided on the inner wall of the semi-ring.

[0020] When the above technical solution is adopted, fixing the test tube to the test tube fixing device increases the contact area between the locking block, the anti-slip pad, and the test tube, thus enhancing the stability of the test tube. Furthermore, the anti-slip pad provides cushioning, preventing the test tube from breaking.

[0021] More preferably, the test tube fixing mechanism further includes:

[0022] The countersunk hole is located at the end of the through hole away from the semi-circle, and the countersunk hole is coaxial with the through hole.

[0023] The handle is located at one end of the fixing rod near the countersunk hole, with its inner end extending into the countersunk hole.

[0024] The elastic element is a spring, which is installed inside the countersunk hole.

[0025] When the above technical solution is adopted, the countersunk hole makes it easier to fix and accommodate the spring, the handle makes operation more convenient, and the combination of the handle, countersunk hole, and spring makes the layout more compact. At the same time, springs, as elastic components, are relatively mature in the market, further reducing manufacturing and procurement costs.

[0026] A further preferred embodiment is that a groove is provided on the outer surface of the support, and the air guide tube is embedded in the groove.

[0027] When the above technical solution is adopted, the overall layout is compact because the air duct is installed in a groove on the outer surface of the bracket. Furthermore, since the air duct and airbag are fixed, the airbag is less prone to shaking, making operation more convenient.

[0028] A further preferred embodiment is that buffer strips are symmetrically arranged on the opposite surfaces of the two fixed arms on both sides of the bracket.

[0029] When the above technical solution is adopted, the support is installed at the opening of the beaker. Due to the buffer strip, the stability of the contact between the support and the beaker is further enhanced, and the beaker is also protected.

[0030] A further preferred embodiment is that the inflation component is an inflatable airbag.

[0031] When the above technical solution is adopted, when the ice melts and the liquid level in the beaker drops, the inflation bladder is manually pressed to fill the regulating bladder with gas. The volume of the regulating bladder increases, so that the liquid level of the ice-water mixture in the beaker is restored to the predetermined height. The cooling medium can continuously surround the test tube to cool the ultrasonic probe, which is convenient to use.

[0032] A further preferred embodiment is that a control valve is provided at the connection between the inflatable airbag and the air duct, and the control valve is used to control the gas flow rate.

[0033] When the above technical solution is adopted, the gas flow rate is controllable by controlling the valve, preventing gas leakage from the regulating bladder and ensuring a stable liquid level, making it convenient to use.

[0034] In summary, compared with the prior art, the present invention has the following beneficial effects:

[0035] 1. This utility model can adjust the liquid level of the cooling medium (ice-water mixture) by controlling and adjusting the size of the airbag. The ice-water mixture has better envelopment of the test tube and better cooling persistence, thus ensuring the cooling effect.

[0036] 2. When adding an ice-water mixture, the liquid level does not need to be precisely positioned; when it is necessary to add ice, the air bladder can be contracted, an appropriate amount of ice can be added to restore the liquid level, or the air bladder can be contracted.

[0037] 3. When the liquid level in the beaker is too high, the beaker can be tilted to pour the water directly out without disassembling the device, making it convenient to use. Attached Figure Description

[0038] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0039] Figure 2 This is a schematic diagram of the main structure of the present invention in use.

[0040] Figure 3 This is a top view of the structure of this utility model;

[0041] Figure 4 This is a schematic diagram of the left-side structure of this utility model;

[0042] Figure 5 This is a partial cross-sectional view of the countersunk hole location of this utility model.

[0043] In the diagram, 1-half ring, 2-block, 3-fixed rod, 4-handle, 5-bracket, 6-buffer strip, 7-air duct, 8-inflatable airbag, 9-adjustable airbag, 10-anti-slip pad, 11-spring, 12-counterhead, 13-first fixed arm, 14-second fixed arm, 15-groove, 16-control valve, 17-through hole, 18-test tube, 19-cooling medium, 20-beaker. Detailed Implementation

[0044] The following is in conjunction with the appendix Figure 1-5 The present invention will be further described in detail with reference to the embodiments.

[0045] In routine laboratory and medical testing, ultrasonic disruptors are frequently used to break down tissues and cells to extract proteins, enzymes, and other substances. However, the ultrasonic probe generates heat during operation, which can affect the stability of in vitro biological organic molecules and even degrade them. This can lead to deviations in subsequent experimental results, such as protein content determination, and may even result in false negatives or false positives. Currently, some laboratory personnel typically immerse test tubes in ice water to cool them down during ultrasonic disruption.

[0046] Chinese Patent Application No. 201310622227.5 discloses an ultrasonic crushing cup for holding samples during ultrasonic crushing, comprising an ice cylinder containing a cooling medium and an inner crushing cup for holding the sample, as well as an outer lid screwed to the ice cylinder and an upper lid screwed to the outer lid. In this invention, the ice cylinder provides a low temperature for the sample in the inner crushing cup. Due to the outer lid, the mist or foam generated by the sample in the inner crushing cup during ultrasonication is less likely to diffuse into the environment, preventing environmental harm.

[0047] Regarding the aforementioned technologies, when using this ultrasonic crushing cup, as the ice in the ice bucket that is in direct contact with the inner crushing cup gradually melts during operation, the ice layer height decreases, the heat dissipation area in direct contact with the inner crushing cup gradually decreases, the envelopment of the test tube is poor, and the cooling effect is reduced.

[0048] Based on the above-mentioned technical problems, the applicant has conceived the following technical solutions:

[0049] The clamp is fixed to the side wall of the beaker, and the beaker is filled with cooling medium (ice-water mixture). One end of the gas delivery tube is connected to the gas inflation assembly, which is placed outside the beaker. The end of the gas delivery tube away from the gas inflation assembly is connected to the regulating air bladder, which is submerged in the cooling medium. The test tube is fixed to the support using the test tube fixing mechanism and placed in the cooling medium. The gas inflation assembly inflates or deflates the regulating air bladder through the gas delivery tube to adjust its volume, thereby adjusting the height of the cooling medium level. This ensures the cooling medium effectively envelops the test tube and provides sustained cooling, thus guaranteeing a better cooling effect.

[0050] Based on the above concept, the applicant has proposed the technical solution of this application, as follows:

[0051] A test tube cooling device, such as Figures 1 to 5 As shown, it includes: a support 5; a test tube fixing mechanism, mounted on the support 5, for fixing the test tube 18 to the support 5; an adjusting air bladder 9, which is immersed in the cooling medium 19 during use; a gas guide tube 7, one end of which is connected to the adjusting air bladder 9; and an inflation assembly, connected to the end of the gas guide tube 7 away from the adjusting air bladder 9, for inflating or deflating the adjusting air bladder 9 through the gas guide tube 7 to adjust the volume of the adjusting air bladder 9, thereby adjusting the liquid level of the cooling medium 19.

[0052] When using this test tube cooling device, add an appropriate amount of cooling medium 19 (ice-water mixture) to beaker 20, immerse the regulating bladder 9 in the cooling medium 19, fix the test tube 18 on the test tube fixing device, and adjust the position of the test tube 18 in the cooling medium 19. Add the test sample to the test tube 18, and then start the ultrasonic disruptor. The ultrasonic probe of the ultrasonic disruptor works in the test tube 18. When the ice in the ice-water mixture melts, causing the liquid level to drop, gas is injected into the regulating bladder 9 through the inflation component to adjust the volume of the regulating bladder 9, thereby restoring the liquid level of the ice-water mixture in beaker 20 to the predetermined height. The cooling medium 19 can continuously surround the test tube 18, cooling the ultrasonic probe. When it is observed that the ice in beaker 20 has basically melted and the cooling effect decreases, the gas in the inflation bladder 8 is sucked out through the inflation component, the volume of the regulating bladder 9 decreases, and more space is created in beaker 20 for adding ice, restoring the cooling medium 19 to the state of an ice-water mixture.

[0053] Specifically, such as Figure 1 , Figure 2 , Figure 3 , Figure 4 As shown, the surface of the regulating airbag 9 forms a wrinkled shape when it contracts. The advantage is that the volume change of the regulating airbag 9 during contraction is large, thus expanding the adjustable range of the liquid level.

[0054] Specifically, such as Figure 2 As shown, the support 5 includes a first fixed arm 13 and a second fixed arm 14 arranged opposite to each other. The first fixed arm 13 and the second fixed arm 14 are fixedly connected at one end, and the included angle between them is an acute angle. In use, it is clamped onto the side wall of the beaker 20 containing the cooling medium 19. The advantage is that it makes the test tube 18 stable in the position of the cooling medium 19, not easy to move, and has better stability.

[0055] Specifically, such as Figure 1 , Figure 2 , Figure 3 , Figure 5As shown, the test tube fixing mechanism includes: a through hole 17, passing through the support 5; a fixing rod 3, passing through the through hole 17 and slidably connected to the support 5, with the sliding direction along the length of the fixing rod 3; a semi-ring 1, disposed at one end of the support 5, with its concave side corresponding to the end of the fixing rod 3; and an elastic element, one end connected to the fixing rod 3 and the other end connected to the support 5, used to apply force to the fixing rod 3 so that the fixing rod 3 moves toward the semi-ring 1, thereby clamping and fixing the test tube 18 between the semi-ring 1 and the fixing rod 3.

[0056] The advantage is that when using it, you can manually pull the fixing rod 3 to create a space between the fixing rod 3 and the semi-ring 1, place the test tube 18 in the space, and then release the fixing rod 3. Due to the interaction between the fixing rod 3 and the semi-ring 1, as well as the clamping effect of the elastic element, the fixing rod 3 and the semi-ring 1 hold the test tube 18 tightly, thereby fixing the test tube 18. The operation is convenient.

[0057] Specifically, such as Figure 1 , Figure 3 As shown, a locking block 2 is provided at one end of the fixing rod 3 corresponding to the semi-ring 1, and an anti-slip pad 10 is provided on the inner wall of the semi-ring 1. The advantage is that when using it, the test tube 18 is fixed on the test tube fixing device. On the one hand, the contact area between the locking block 2, the anti-slip pad 10 and the test tube 18 is increased, which enhances the stability of the test tube 18; on the other hand, the anti-slip pad 10 can play a buffering role, thereby avoiding damage to the test tube 18.

[0058] Specifically, such as Figure 5 As shown, the test tube fixing device also includes: a countersunk hole 12, located at the end of the through hole 17 away from the semi-ring 1, with the countersunk hole 12 and the through hole 17 coaxial; a handle 4, located at the end of the fixing rod 3 near the countersunk hole 12, with its inner end extending into the countersunk hole 12; and a spring 11, an elastic element located within the countersunk hole 12. The advantages are that the countersunk hole 12 facilitates fixing and accommodating the spring 11, the handle 4 makes operation more convenient, and the combination of the handle 4, the countersunk hole 12, and the spring 11 results in a more compact layout. Furthermore, the spring 11, as an elastic element, is relatively mature in the market, further reducing manufacturing and procurement costs.

[0059] Specifically, such as Figure 1 , Figure 3 , Figure 4 As shown, a groove 15 is provided on the outer surface of the bracket 5, and the air guide tube 7 is installed in the groove 15. The advantage is that because the air guide tube 7 is installed in the groove 15 on the outer surface of the bracket 5, the overall layout is compact. Furthermore, the fixed air guide tube 7 also helps to fix the adjustable airbag 9, making it less prone to shaking and more convenient to use.

[0060] Specifically, such as Figure 1 , Figure 2 , Figure 3 , Figure 4As shown, buffer strips 6 are symmetrically provided on the opposite surfaces of the first fixed arm 13 and the second fixed arm 14 of the bracket 5. The advantage is that when the bracket 5 is installed at the opening of the beaker 20, the contact stability between the bracket 5 and the beaker 20 is further enhanced due to the buffer strips 6, and the beaker 20 is also protected.

[0061] Specifically, such as Figure 1 , Figure 2 , Figure 3 , Figure 4 As shown, the inflation component is the inflation bladder 8. Its advantage is that during use, when the ice melts and the liquid level in the beaker 20 drops, the inflation bladder 8 can be manually pressed to inflate the regulating bladder 9. The volume of the regulating bladder 9 increases, allowing the liquid level of the ice-water mixture in the beaker 20 to return to the predetermined height. The cooling medium 19 can then continuously surround the test tube 18, cooling the ultrasonic probe. This makes it convenient to use.

[0062] Specifically, such as Figure 1 , Figure 2 , Figure 3 As shown, a control valve 16 is installed at the connection between the inflatable airbag 8 and the air guide tube 7. The gas flow can be controlled by the control valve 16, preventing gas leakage from the regulating airbag 9, ensuring a stable liquid level, and making it convenient to use.

[0063] Working principle and process

[0064] Please combine Figures 1-5 The principle and process of this utility model are described in detail below:

[0065] S1. Add cooling medium 19 (ice-water mixture) to beaker 20, and clamp the support 5 onto the side wall of beaker 20. The buffer strips 6 symmetrically arranged on the opposite surfaces of the first fixing arm 13 and the second fixing arm 14 of the support 5 clamp the side wall of beaker 20, thereby fixing the clamp 5 to the side wall of beaker 20. Embed the gas guide tube 7 into the groove 15 provided on the outer surface of the support 5, and immerse the regulating air bag 9 in the cooling medium 19.

[0066] S2. Manually pull the handle 4 outward to create a space between the locking block 2 and the half ring 1. Place the test tube 18 in the space, and then release the handle 4. Due to the interaction between the locking block 2 and the half ring 1, as well as the clamping action of the spring 11, the locking block 2 and the half ring 1 hold the test tube 18 tightly, thereby fixing the test tube 18 to the support 5.

[0067] S3. Add reagents to test tube 18, then start the ultrasonic disruptor. The ultrasonic probe of the ultrasonic disruptor operates in test tube 18. When the ice in the ice-water mixture melts, causing the liquid level to drop, manually press the inflation bladder 8 to fill the regulating bladder 9 with gas. Close the control valve 16 to increase the volume of the regulating bladder 9, so that the liquid level of the ice-water mixture in beaker 20 returns to the predetermined height. The cooling medium 19 can continuously surround the test tube 18 to cool the ultrasonic probe. When it is observed that the ice in beaker 20 has basically melted and the cooling effect decreases, open the control valve 16, manually press the inflation bladder 8 to draw out the gas in the inflation bladder 8, and decrease the volume of the regulating bladder 9. More space is created in beaker 20 for adding ice, so that the cooling medium 19 returns to the state of an ice-water mixture. If the liquid level in beaker 20 is too high, water can be poured directly from beaker 20 for ice replenishment without disassembling the device.

[0068] S4. After using the ultrasonic breaker, disassemble the device for cleaning and wait for the next cycle.

[0069] In summary, this specific embodiment is merely an explanation of the utility model and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of protection of this utility model.

Claims

1. A test tube cooling device, characterized in that... ,include: Frame (5); A test tube fixing mechanism is installed on the bracket (5) and is used to fix the test tube (18) to the bracket (5); Adjust the airbag (9) and immerse it in the cooling medium (19) during use; An air duct (7), one end of which is connected to the regulating airbag (9); The inflation assembly is connected to the end of the air guide pipe (7) away from the regulating air bag (9) and is used to inflate or deflate the regulating air bag (9) through the air guide pipe (7) to adjust the volume of the regulating air bag (9) and thus adjust the liquid level of the cooling medium (19).

2. The test tube cooling device according to claim 1, characterized in that... The surface of the regulating airbag (9) is wrinkled when it contracts.

3. The test tube cooling device according to claim 1, characterized in that... The bracket (5) includes a first fixed arm (13) and a second fixed arm (14) arranged opposite to each other, and one end of the first fixed arm (13) and the second fixed arm (14) are fixedly connected.

4. The test tube cooling device according to claim 1, characterized in that... The test tube fixing mechanism includes: Through hole (17), penetrating the bracket (5); The fixing rod (3) passes through the through hole (17) and is slidably connected to the bracket (5), with the sliding direction along the length of the fixing rod (3); A semi-ring (1) is provided at one end of the bracket (5), and its concave side corresponds to the end of the fixing rod (3); An elastic element, one end of which is connected to the fixed rod (3) and the other end of which is connected to the bracket (5), is used to apply force to the fixed rod (3) so that the fixed rod (3) moves toward the semi-ring (1), thereby clamping and fixing the test tube (18) between the semi-ring (1) and the fixed rod (3).

5. The test tube cooling device according to claim 4, characterized in that... The fixing rod (3) is provided with a locking block (2) at one end of the semi-ring (1), and an anti-slip pad (10) is provided on the inner wall of the semi-ring (1).

6. The test tube cooling device according to claim 4, characterized in that... It also includes: A countersunk hole (12) is provided at one end of the through hole (17) away from the semi-ring (1), and the countersunk hole (12) is coaxial with the through hole (17); A handle (4) is provided at one end of the fixed rod (3) near the countersunk hole (12), with its inner end extending into the countersunk hole (12); The elastic element is a spring (11), which is disposed in the countersunk hole (12).

7. The test tube cooling device according to claim 3, characterized in that... A groove (15) is provided on the outer surface of the bracket (5), and the air guide tube (7) is embedded in the groove (15).

8. A test tube cooling device according to claim 3, characterized in that... The first fixed arm (13) and the second fixed arm (14) of the bracket (5) are symmetrically provided with buffer strips (6) on their opposite surfaces.

9. A test tube cooling device according to claim 3, characterized in that... The inflation component is an inflatable airbag (8).

10. A test tube cooling device according to claim 9, characterized in that... A control valve (16) is provided at the connection between the inflatable airbag (8) and the air duct (7), and the control valve (16) is used to control the gas flow rate.

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