Liquid mixer

Abstract

The utility model relates to the technical field of reagent mixing equipment in the fields of biology and pharmacy, in particular to a liquid mixer, which comprises a tube seat provided with a clamping hole, a driving module for driving the tube seat to swing back and forth, and a controller for controlling the driving module. The clamping hole in the tube seat is used for placing the reagent tube starting driving module, and the reagent tube can swing back and forth to start the uniform mixing effect. The utility model is very suitable for uniformly mixing the solution of the PCR reagent tube.

Description

TECHNICAL FIELD

[0001] The utility model relates to reagent mixing equipment technical field in biological, pharmaceutical field, concretely is liquid mixer. BACKGROUND

[0002] Reagent mixing is the most common operation in the fields of biochemistry, pharmacy, chemical synthesis, etc. Whether in the laboratory or in production, accurate and rapid mixing of reagents is crucial to ensure the accuracy of experimental results and the quality of drugs. Especially in the research fields of biochemistry, drug research and development, cell culture, and gene research, uniform mixing of reagents and samples not only affects the reaction efficiency, but also may determine the success or failure of the experiment. Current mixing techniques mostly use vortex mixers, which mainly work by generating a vortex effect through motor-driven rotational motion, causing the liquid in the test tube to rotate rapidly and generate a vortex, thereby achieving efficient and uniform mixing. With the application of freeze-drying technology in the fields of biochemistry and pharmacy, PCR tubes containing freeze-dried reagents also need to be reconstituted and mixed. Since PCR tubes are small and not suitable for vortex mixing, and cannot be mixed simultaneously in a row such as eight-tube PCR, the different mixing degrees cannot guarantee the accuracy of the results when conducting comparative experiments, therefore, designing a new liquid mixer suitable for PCR tubes and eight-tube PCR tubes has become an urgent requirement. SUMMARY

[0003] The technical problem to be solved by the utility model is to design a liquid mixer suitable for PCR tubes and eight-tube PCR.

[0004] The technical solution to the technical problem to be solved by the utility model is a liquid mixer, including a tube seat, a drive module, and a controller. The tube seat has an axis in the length direction, and a card hole is arranged on the upper part to clamp the PCR tube. The drive module is connected to the shaft to drive the tube seat to reciprocate. The controller is electrically connected to the drive module to control the drive module.

[0005] Better, the card hole is arranged in eight rows in the length direction of the tube seat to clamp the eight-tube PCR.

[0006] Better, the card hole is arranged in two rows, and the two rows of card holes are symmetrical about the axis.

[0007] Better, it also includes a machine shell, the drive module, the controller, and the power module are arranged inside the machine shell. A bottom plate is arranged on the side of the machine shell extending from the bottom edge. The end of the bottom plate is provided with a shaft support. The shaft of the tube seat is arranged on the outer wall of the shaft support and the machine shell, and extends into the machine shell to connect with the drive module.

[0008] Better, the tube seat is provided with two.

[0009] Better, the driving module comprises a motor, the motor converts the rotation output of the motor into swing output through a crank rocker mechanism or a cam mechanism, and an output shaft of the crank rocker mechanism or the cam mechanism is connected with the rotating shaft of the tube seat.

[0010] Better, the card hole is internally provided with a rubber ring.

[0011] Better, the upper portion of the bottom plate is provided with a protective cover.

[0012] Better, the shell is provided with a switch and a speed knob for controlling the start-stop and rotating speed of the driving module.

[0013] The utility model discloses a liquid mixing device, which can realize rapid liquid mixing and rapid liquid mixing of PCR tubes and eight connecting tubes. BRIEF DESCRIPTION OF DRAWINGS

[0014] Figure 1 is the three-dimensional schematic view of one embodiment of the utility model.

[0015] Figure 2 is the top view of one embodiment of the utility model.

[0016] Figure 3 is the front view of one embodiment of the utility model.

[0017] In the drawing: 100, tube seat; 110, card hole; 200, shell; 210, bottom plate; 220, rotating shaft support; DETAILED DESCRIPTION

[0018] In order to make the technical scheme setting and beneficial effects of the utility model clearer, the following further explains the embodiment of the utility model in detail.

[0019] A liquid mixing device comprises a tube seat 100, which is long and rectangular. A rotating shaft is installed on the axial line of the tube seat 100 in the length direction. The tube seat 100 is provided with a card hole 110 for clamping a PCR tube on the upper portion, and has a certain thickness to ensure the clamping and fixing of the PCR tube. As shown in the drawing, the middle portion of the tube seat 100 in the length direction is provided with a through hole, the rotating shaft is inserted into the through hole, the upper portion of the tube seat 100 is provided with a screw hole, the screw hole is perpendicular to the axial line of the through hole of the inserted rotating shaft, and the fixing between the rotating shaft and the tube seat 100 is realized by arranging a bolt in the screw hole. In addition, a convex shaft can be extended outward from the end portion of the tube seat 100 in the axial direction as the rotating shaft.

[0020] The organic shell 200 is provided in the embodiment. The driving module, the controller and the power module are arranged inside the shell 200, as shown in the figure, the bottom plate 210 is arranged at one side of the shell 200 and extends from the bottom edge, and the end of the bottom plate 210 is provided with the rotating shaft support 220. The rotating shaft of the pipe seat 100 is arranged on the outer wall of the rotating shaft support 220 and the shell 200, and the rotating shaft can be rotatably connected with the rotating shaft support 220 and the outer wall of the shell 200 through bearings. At the same time, the end of the rotating shaft extends into the shell 200 and is connected with the driving module. The driving module drives the rotating shaft to reciprocating rotate, thereby driving the pipe seat 100 to reciprocating swing left and right.

[0021] The driving module includes a motor, which converts the rotating output of the motor into a swinging output through a crank rocker mechanism or a cam mechanism. The output shaft of the crank rocker mechanism or the cam mechanism is connected with the rotating shaft of the pipe seat 100. For specific examples, please refer to the patent previously applied by the company, with the publication number CN221046267U.

[0022] A switched reluctance motor can also be used as a driving module, and the rotating shaft of the switched reluctance motor is directly connected with the rotating shaft of the pipe seat 100. Due to the characteristics of the switched reluctance motor, reciprocating rotation can be realized, thereby realizing the driving of swinging.

[0023] The controller and the power module are arranged inside the shell 200, wherein the controller is a control module or a control circuit for controlling the rotation of the motor. For example, the speed of a common motor can be controlled by a voltage regulator, and a stepper motor and a reluctance motor need to be configured with a corresponding control module. In order to realize the effect of being convenient to carry and use, the power module can be provided with a charging module and a battery. In order to realize the control of the switch and the adjustment of the speed, a speed knob and a start-stop switch are arranged on the surface of the shell 200, and the speed knob and the start-stop switch are connected in series in the controller. The speed knob is used to adjust the frequency of swinging. The switch is used to start and stop swinging.

[0024] In order to realize the mixing of multiple or rowed PCR tubes, the card hole 110 is arranged in eight rows in the length direction of the pipe seat 100, and is used to clamp the PCR eight-tube.

[0025] Further, the card hole 110 is arranged in two rows, and the two rows of card holes 110 are symmetrical about the axis. At this time, multiple groups of eight-tubes can be mixed at the same time.

[0026] Better, in order to ensure the stability and firmness of the clamped PCR reagent tube, a rubber ring is embedded in the inner wall of the card hole 110. The inner diameter of the small rubber ring is slightly smaller than the inner diameter of the card hole 110 and also slightly smaller than the outer diameter of the upper part of the reagent tube, thereby realizing stable and firm clamping in the form of extrusion, and the firmness is better when clamping the eight-tube.

[0027] Further, two pipe seats 100 are arranged on the bottom plate. The two pipe seats can be independently configured with driving modules, or can share a driving module driven by a driving motor.

[0028] Better, in order to realize the protection of reagent, while preventing accidental injury to people, the upper part of the bottom plate 210 is provided with a protective cover.

[0029] When the solution needs to be mixed, the PCR tube with the solution is put into the card hole. Then the machine can be started to mix the solution. Unlike the prior art, the utility model is not a vortex type mixing, nor is it a simple swing type mixing. The swing mixing is that the upper part of the reagent tube remains unchanged, and the lower part swings back and forth from a certain point of the upper part. The utility model is that the reagent tube as a whole swings, and the reagent tube as a whole swings along the axis of the pipe seat 100. Not only can the liquid be shaken to realize mixing when the direction is changed, but also the liquid can flow in the whole swing process, so that rapid mixing can be realized, because the whole reagent tube changes its orientation continuously in the whole swing period.

[0030] In summary, only the preferred embodiments of the utility model are described, and the scope of the utility model is not limited. Through the above description, relevant personnel can make various changes and modifications without deviating from the technical idea of the utility model. The technical scope of the utility model is not limited to the content in the specification. Any equivalent changes and modifications of shape, structure, features and spirit within the scope of the utility model should be included in the scope of the utility model.

Claims

1. A liquid mixer, characterized in that it comprises: a tube holder (100) having a rotating shaft mounted on the axis of the length direction, and an upper portion provided with clamping holes (110) for clamping PCR tubes; a driving module connected with the rotating shaft to drive the tube holder (100) to reciprocating swing; a controller electrically connected with the driving module to control the driving module.

2. The liquid mixer according to claim 1, characterized in that: the clamping holes (110) are arranged in eight rows in the length direction of the tube holder (100) to clamp eight PCR tubes.

3. The liquid mixer according to claim 1 or 2, characterized in that: the clamping holes (110) are arranged in two rows, and the two rows of clamping holes (110) are symmetrical about the axis.

4. The liquid mixer according to claim 3, characterized in that: it further comprises a casing (200), the driving module, the controller, and a power module are arranged inside the casing (200), a bottom plate (210) is arranged on the side of the casing (200) and extends from the bottom edge, an end of the bottom plate (210) is provided with a rotating shaft support (220), the rotating shaft of the tube holder (100) is arranged on the outer wall of the rotating shaft support (220) and the casing (200), and extends into the casing (200) and is connected with the driving module.

5. The liquid mixer according to claim 2 or 4, characterized in that: the tube holder (100) is arranged in two.

6. The liquid mixer according to claim 5, characterized in that: the driving module comprises a motor, the motor converts the rotating output of the motor into swinging output through a crank rocker mechanism or a cam mechanism, and the output shaft of the crank rocker mechanism or the cam mechanism is connected with the rotating shaft of the tube holder (100).

7. The liquid mixer according to claim 5, characterized in that: a rubber ring is arranged inside the clamping hole.

8. The liquid mixer according to claim 4, characterized in that: a protective cover is arranged on the upper portion of the bottom plate (210).

9. The liquid mixer according to claim 4, characterized in that: switches and speed adjusting knobs for controlling the start and stop of the driving module and the rotating speed are arranged on the casing. ​

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