Centrifugal device and mass-liquid separation device

Abstract

The utility model relates to the technical field of centrifugal separation, and discloses a centrifugal device and a mass-liquid separation device. The swing frame is at least provided with an inclined position; the rotary driving mechanism is arranged on the swing frame; and the sample container fixing structure is connected with the rotary driving mechanism, is suitable for rotating under the driving of the rotary driving mechanism, is used for fixing the sample container, and is obliquely arranged when the swing frame is in the inclined position. According to the utility model, the supernate can be completely sucked, and the supernate and the centrifugal precipitate can be effectively separated.

Description

TECHNICAL FIELD

[0001] The utility model relates to centrifugal separation technical field, concretely relates to centrifugal device and liquid separation device. BACKGROUND

[0002] The centrifugal device is a kind of equipment using centrifugal force to separate matter, and different components in mixture can be separated according to density, particle size, specific surface area and other physical properties.The centrifugal device is usually composed of rotor, motor, control system and sample container etc.The mixture in sample container is subjected to centrifugal force in high-speed rotating rotor, so that different components are separated.

[0003] Under the action of gravity, centrifugal precipitation usually concentrates to the corner of sample container, since centrifugal precipitation itself has certain adhesion or viscosity, it can make centrifugal precipitation in the corner of the bottom of sample container into cluster or block.

[0004] The pipette can extract supernatant in sample container, but it is difficult to extract supernatant cleanly in the related art, and effective separation of centrifugal precipitation and supernatant cannot be realized. UTILITY MODEL CONTENT

[0005] Therefore, the utility model provides a kind of centrifugal device and liquid separation device to solve the problem that it is difficult to extract supernatant cleanly in the related art.

[0006] Firstly, the utility model provides a kind of centrifugal device, comprising:

[0007] Fixed frame;

[0008] Swing frame, the swing frame at least has inclined position;

[0009] Rotary drive mechanism, is located in the swing frame;

[0010] Sample container fixing structure is connected with the rotary drive mechanism, is suitable for rotating under the drive of the rotary drive mechanism, and the sample container fixing structure is used to fix sample container, and the sample container fixing structure is inclinedly arranged when the swing frame is in the inclined position.

[0011] Beneficial effects: when separating the supernatant and the centrifugal precipitate, the pipette needle tube can first move downward into the sample container, close to the bottom of the sample container and a certain distance from the bottom of the sample container, and then start to suck, to suck a large amount of supernatant in the sample container. Then, due to the fact that the swing frame is in the inclined position, the sample container fixing structure is inclined, and the sample container fixed to the sample container fixing structure is inclined, at this time, under the action of gravity, the centrifugal precipitate moves to the bottom of the sample container. Due to the fact that the centrifugal precipitate has certain adhesion or viscosity, it will remain in this position. Then, the rotary drive mechanism drives the sample container fixing structure to rotate a certain angle, and the centrifugal precipitate rotates with the sample container. The centrifugal precipitate rotates to a position away from the bottom of the sample container. At this time, the pipette needle tube can be extended to the bottom of the sample container for suction, so that the supernatant can be completely sucked. Therefore, the centrifugal device can completely suck the supernatant and effectively separate the supernatant and the centrifugal precipitate.

[0012] In an alternative embodiment, the swing frame also has a vertical position, and when the swing frame is in the vertical position, the sample container fixing structure is vertically arranged.

[0013] Beneficial effects: when the swing frame is in the vertical position, the sample container fixing structure is vertically arranged, so that when the sample container is fixed to the sample container fixing structure, the sample container is vertically arranged. At this time, the pipette needle tube can move downward into the sample container, close to the center of the bottom of the sample container and a certain distance from the bottom of the sample container. Then start to suck, to suck a large amount of supernatant in the sample container. When the sample container is vertically arranged, it is convenient for the pipette needle tube to extend into the sample container, and the pipette needle tube is not easy to touch the side wall of the sample container, so that suction can be easily performed. At the beginning, when there is a lot of liquid in the sample container, the sample container remains vertical, and the liquid is not easy to overflow. Then, the swing frame is swung to the inclined position.

[0014] In an alternative embodiment, the centrifugal device comprises an inclination drive mechanism, and the swing frame can be swung relative to the fixed frame under the drive of the inclination drive mechanism, so that the swing frame has the inclined position and the vertical position.

[0015] Beneficial effects: the inclination drive mechanism can drive the swing frame to swing, so that the swing frame has the vertical position and the inclined position. The swing frame can be swung by the inclination drive mechanism, without the need for manual operation by the user, reducing manual operation.

[0016] In an alternative embodiment, the swing frame is L-shaped, comprising a longitudinal portion and a horizontal portion, the longitudinal portion is connected with the inclination drive mechanism, and the rotary drive mechanism is arranged on the horizontal portion.

[0017] Beneficial effect: the inclined driving mechanism is connected with the longitudinal part, and the horizontal part swings by driving the longitudinal part to swing, and since the rotary driving mechanism is arranged on the horizontal part, the rotary driving mechanism swings along with the horizontal part.

[0018] In an alternative embodiment, one end of the longitudinal part away from the horizontal part is connected with the output shaft of the inclined driving mechanism, and the output shaft of the inclined driving mechanism is arranged horizontally.

[0019] Beneficial effect: since the output shaft of the inclined driving mechanism is arranged horizontally, the swing frame can swing in the vertical plane perpendicular to the ground.

[0020] In an alternative embodiment, the rotary driving mechanism is connected with the sample container fixing structure through a clutch mechanism.

[0021] Beneficial effect: since the rotary driving mechanism is connected with the sample container fixing structure through the clutch mechanism, when the clutch mechanism is connected with the sample container fixing structure, the rotary driving mechanism can drive the sample container fixing structure to rotate, and when the clutch mechanism is separated from the sample container fixing structure, the sample container fixing structure no longer rotates along with the rotary driving mechanism.

[0022] In an alternative embodiment, the rotary driving mechanism is a brushless motor.

[0023] Beneficial effect: the output shaft of the brushless motor is directly connected with the sample container fixing structure, and whether the sample container rotates or not can be controlled by turning on or off the power supply of the brushless motor.

[0024] In an alternative embodiment, the sample container fixing structure is a cup sleeve, and the sample container is adapted to be inserted into the cup sleeve.

[0025] Beneficial effect: since the sample container fixing structure is the cup sleeve, the sample container can be fixed in the cup sleeve.

[0026] In an alternative embodiment, the cup sleeve is adapted to be in interference fit with the sample container.

[0027] Alternatively, a flexible structure is filled between the cup sleeve and the sample container.

[0028] Beneficial effect: since the cup sleeve is adapted to be in interference fit with the sample container, the sample container can be fixed in the cup sleeve without the help of additional structures, and the fixing of the sample container is simple and convenient. The flexible structure filled between the cup sleeve and the sample container can fix the sample container in the cup sleeve, and the size requirement of the cup sleeve can be reduced.

[0029] In an alternative embodiment, the cup sleeve is made of soft material or hard material.

[0030] Beneficial effect: since the cup sleeve is made of soft material, the sample container can be firmly fixed through the elasticity of the cup sleeve.

[0031] In a second aspect, the utility model also provides a kind of liquid separation device, comprising:

[0032] Pipette tip;

[0033] The centrifugal device, when the swing frame is in the inclined position and the sample container fixing structure is fixed with a sample container, the pipette tip is opposite to the bottom of the sample container.

[0034] Beneficial effect: when separating supernatant and centrifugal precipitate, the pipette tip can be moved downward into the sample container first, close to the bottom of the sample container and have a certain distance from the bottom of the sample container, then start to suck and take a large amount of supernatant in the sample container. Then, swing the swing frame to the inclined position, at this time the sample container fixing structure is vertically inclined, the sample container fixed to the sample container fixing structure is inclined, at this time under the action of gravity, centrifugal precipitate moves to the bottom of the sample container, and because centrifugal precipitate has certain adhesion or viscosity, it will remain in this position. Then, the rotary drive mechanism drives the sample container fixing structure to rotate a certain angle, and the centrifugal precipitate rotates with the sample container. The centrifugal precipitate rotates to a position away from the bottom of the sample container, at this time the pipette tip can be extended to the bottom of the sample container to suck liquid, so that the supernatant can be completely sucked. Therefore, the liquid separation device can completely suck the supernatant and effectively separate the supernatant and centrifugal precipitate.

[0035] In an alternative embodiment, the liquid separation device further comprises a distance sensor and a controller, the distance sensor is arranged on the pipette tip, and the controller is in communication connection with the distance sensor and the rotary drive mechanism.

[0036] Beneficial effect: when the sample container fixing structure moves the centrifugal precipitate in the sample container below the distance sensor, the distance information detected by the distance sensor is obviously different from that without centrifugal precipitate, i.e. it can be judged that there is centrifugal precipitate, so that the controller can automatically control the operation of the rotary drive mechanism to rotate a certain angle, and the automatic control of liquid separation can be realized.

[0037] In an alternative embodiment, the liquid separation device further comprises a scanning device and a controller, the scanning device is used to detect the position of the centrifugal precipitate, and the controller is in communication connection with the scanning device and the rotary drive mechanism.

[0038] Beneficial effect: the position of centrifugal precipitation can be detected by the scanning device, and then the rotating driving mechanism is controlled to work, so that the automatic control of liquid-solid separation is realized. BRIEF DESCRIPTION OF DRAWINGS

[0039] In order to more clearly illustrate the specific embodiments of the present application or the technical solutions in the prior art, the drawings needed in the following description of the specific embodiments or the prior art will be briefly introduced. Obviously, the drawings described below are some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained without creative labor on the basis of these drawings.

[0040] Figure 1 A structural schematic view of the liquid-solid separation device of the embodiment of the present application at one viewing angle;

[0041] Figure 2 A structural schematic view of the liquid-solid separation device of the embodiment of the present application at another viewing angle;

[0042] Figure 3 A perspective view of the liquid-solid separation device shown in the figure; Figure 1

[0043] Figure 4 A schematic view of the liquid-solid separation device of the embodiment of the present application when containing a mechanical arm and a base.

[0044] Explanation of reference signs:

[0045] 1, fixed frame; 101, horizontal plate; 102, vertical plate; 201, inclined driving mechanism; 202, swing frame; 2021, longitudinal part; 2022, horizontal part; 3, rotating driving mechanism; 4, sample container fixing structure; 5, pipette; 6, sample container; 7, centrifugal precipitation; 10, base; 11, mechanical arm; 12, end shaft. DETAILED DESCRIPTION

[0046] In order to make the purpose, technical scheme and advantages of the embodiments of the present application more clear, the technical scheme of the embodiments of the present application will be described clearly and completely below in combination with the drawings in the embodiments of the present application. Obviously, the described embodiments are some embodiments of the present application, not all embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the scope of protection of the present application.

[0047] The embodiments of the present application will be described below in combination with Figures 1 to 4

[0048] ​​According to the embodiment of the utility model, on the one hand, a centrifugal device is provided, which comprises: a fixing frame 1, a swing frame 202, a rotary drive mechanism 3 and a sample container fixing structure 4.

[0049] The swing frame 202 has at least an inclined position; the rotary drive mechanism 3 is arranged on the swing frame 202; the sample container fixing structure 4 is connected with the rotary drive mechanism 3 and is adapted to rotate under the drive of the rotary drive mechanism 3; the sample container fixing structure 4 is used for fixing a sample container 6; when the swing frame 202 is in the inclined position, the sample container fixing structure 4 is arranged obliquely.

[0050] In this embodiment, when separating the supernatant and the centrifugal precipitate, the pipette needle tube 5 can be first moved downward into the sample container 6, close to the bottom of the sample container 6 and have a certain distance from the bottom of the sample container 6, and then the suction is started to suck a large amount of supernatant in the sample container 6. Subsequently, since the swing frame 202 is in the inclined position and the sample container fixing structure 4 is arranged obliquely, the sample container 6 fixed to the sample container fixing structure 4 is also arranged obliquely, at this time, under the action of gravity, the centrifugal precipitate 7 moves to the bottom of the sample container 6, and since the centrifugal precipitate 7 has a certain adhesion or viscosity, it will remain in this position, and then the rotary drive mechanism 3 drives the sample container fixing structure 4 to rotate the sample container 6 by a certain angle, and the centrifugal precipitate 7 rotates with the sample container 6, as shown in FIG. 6, the centrifugal precipitate 7 rotates to a position away from the bottom of the sample container 6, at this time, the pipette needle tube 5 can be extended to the bottom of the sample container 6 to suck the liquid, so that the supernatant can be completely sucked. Therefore, the centrifugal device can completely suck the supernatant and effectively separate the supernatant and the centrifugal precipitate 7. Figure 3

[0051] It should be noted that the swing frame 202 can be in the inclined position all the time, and when the swing frame 202 is in the inclined position, the pipette needle tube 5 can move into the sample container 6 to suck the supernatant in the sample container 6.

[0052] It should be noted that when the swing frame 202 is in the inclined position, the sample container 6 is arranged obliquely, in order to prevent the centrifugal precipitate 7 from moving under the action of gravity after rotating with the sample container 6 to a position away from the bottom of the sample container 6, it is preferred that the inclination angle of the sample container 6 is less than or equal to 45°.

[0053] In one embodiment, the centrifugal precipitate 7 moves to the bottom of the sample container 6, and then the rotary drive mechanism 3 drives the sample container fixing structure 4 to rotate the sample container 6 by 180°, and the centrifugal precipitate 7 rotates with the sample container 6 to a position away from the bottom of the sample container 6.

[0054] ​In one embodiment, the swing rack 202 further has a vertical position, in which the sample container fixing structure 4 is vertically arranged.

[0055] In this embodiment, when the swing rack 202 is in the vertical position, the sample container fixing structure 4 is vertically arranged, and thus when the sample container 6 is fixed to the sample container fixing structure 4, the sample container 6 is vertically arranged. At this time, the pipette 5 can be first moved downward into the sample container 6 to approach the bottom center of the sample container 6 and be a certain distance away from the bottom of the sample container 6, and then start to suck to suck a large amount of supernatant in the sample container 6. When the sample container 6 is vertically arranged, the pipette 5 is not easy to touch the side wall of the sample container 6, which facilitates the pipette 5 to extend into the sample container 6 and facilitates the pipette 5 to suck. At the beginning, when the liquid in the sample container 6 is relatively large, the sample container 6 is kept in the vertical state, and the liquid is not easy to overflow. Then, the swing rack 202 is swung to the inclined position, in which the sample container fixing structure 4 is vertically and obliquely arranged, and the sample container 6 fixed to the sample container fixing structure 4 is obliquely arranged. At this time, under the action of gravity, the centrifugal precipitate 7 moves to the bottom of the sample container 6. Since the centrifugal precipitate 7 has a certain cohesiveness or viscosity, it will remain at this position. Then, the rotation driving mechanism 3 drives the sample container fixing structure 4 to rotate the sample container 6 by a certain angle, and the centrifugal precipitate 7 rotates with the sample container 6. As shown in FIG. 6, the centrifugal precipitate 7 rotates to a position away from the bottom of the sample container 6. At this time, the pipette 5 can be extended to the bottom of the sample container 6 to suck the liquid, so that the supernatant can be completely sucked. Figure 3 Thus, the centrifugal device can completely suck the supernatant and effectively separate the supernatant and the centrifugal precipitate 7.

[0056] In one embodiment, the centrifugal device comprises an inclined driving mechanism 201, and the swing rack 202 can be swung relative to the fixed rack 1 under the driving of the inclined driving mechanism 201, so that the swing rack 202 has an inclined position and a vertical position.

[0057] In this embodiment, the tilting driving mechanism 201 can drive the swing frame 202 to swing, so that the swing frame 202 has a vertical position and a tilting position. The swing frame 202 can be driven to swing by the tilting driving mechanism 201 without manual operation of the user, thereby reducing manual operation. When the swing frame 202 is in the vertical position, the sample container fixing structure 4 is vertically arranged, and thus the sample container 6 is vertically arranged when the sample container 6 is fixed to the sample container fixing structure 4. At this time, the pipette 5 can be moved downward into the sample container 6 to approach the bottom center of the sample container 6 and be away from the bottom of the sample container 6, and then the pipette 5 starts to suck to suck a large amount of supernatant in the sample container 6. Then, the swing frame 202 is driven to swing to the tilting position by the tilting driving mechanism 201. At this time, the sample container fixing structure 4 is vertically arranged, and thus the sample container 6 is vertically arranged when the sample container 6 is fixed to the sample container fixing structure 4. At this time, under the action of gravity, the centrifugal precipitate 7 moves to the bottom of the sample container 6. Since the centrifugal precipitate 7 has a certain adhesion or viscosity, the centrifugal precipitate 7 remains at this position. Then, the rotating driving mechanism 3 drives the sample container fixing structure 4 to rotate the sample container 6 by a certain angle, and the centrifugal precipitate 7 rotates with the sample container 6. As shown in FIG. 7, the centrifugal precipitate 7 rotates to a position away from the bottom of the sample container 6. At this time, the pipette 5 can be extended to the bottom of the sample container 6 to suck the liquid, so that the supernatant can be completely sucked. Therefore, the centrifugal device can completely suck the supernatant and effectively separate the supernatant and the centrifugal precipitate 7. Figure 3

[0058] The centrifugal device of this embodiment can also collect the suspension liquid together with the pipette 5. Specifically, the supernatant is first sucked away by the pipette 5, leaving the centrifugal precipitate 7, for example, E. coli bacteria. Then, the rotating driving mechanism 3 drives the centrifugal precipitate 7 to rotate with the sample container 6 to the bottom of the sample container 6. Then, the pipette 5 adds the resuspension liquid to make the centrifugal precipitate 7 resuspended, thereby generating the suspension liquid. The pipette 5 is extended into the bottom of the sample container 6 to suck the suspension liquid.

[0059] It should be noted that after the resuspension liquid is added, the rotating driving mechanism 3 can be used to drive the sample container fixing structure 4 to rotate the sample container 6 to quickly generate the suspension liquid.

[0060] Specifically, in one embodiment, the sample container 6 is a centrifugal bottle or a centrifugal tube.

[0061] Specifically, in one embodiment, after the centrifugal precipitate 7 moves to the bottom of the sample container 6, the rotating driving mechanism 3 drives the sample container fixing structure 4 to rotate the sample container 6 by 90° to 180°, and the centrifugal precipitate 7 rotates with the sample container 6. The centrifugal precipitate 7 rotates to a position away from the bottom of the sample container 6.

[0062] ​Specifically in one embodiment, such as Figure 1 As shown, the mounting frame 1 includes a horizontal plate 101 and a vertical plate 102. The horizontal plate 101 is suitable for being fixed on the ground or a test bench, and the tilting drive mechanism 201 is connected to the vertical plate 102.

[0063] In one embodiment, the swing frame 202 is L-shaped, including a longitudinal part 2021 and a horizontal part 2022. The longitudinal part 2021 is connected to the tilting drive mechanism 201, and the rotation drive mechanism 3 is disposed in the horizontal part 2022.

[0064] In this embodiment, the tilting drive mechanism 201 is connected to the longitudinal part 2021. By driving the longitudinal part 2021 to swing, the horizontal part 2022 is driven to swing. Since the rotation drive mechanism 3 is located in the horizontal part 2022, the rotation drive mechanism 3 will swing together with the horizontal part 2022.

[0065] In one specific embodiment, the tilting drive mechanism 201 is a motor.

[0066] In one specific embodiment, the tilting drive mechanism 201 may not be provided, and the position of the swing frame 202 may be adjusted by manually swinging the swing frame 202.

[0067] In one specific embodiment, the tilting drive mechanism 201 may include a motor and a gear transmission assembly, the gear transmission assembly including a driving gear and a driven gear, the driven gear being connected to the swing frame 202.

[0068] Specifically, in one embodiment, when the pendulum frame 202 is in a vertical plane perpendicular to the ground, that is, in a vertical position, and when the pendulum frame 202 is tilted, that is, in an tilted position, combined with... Figure 1 and Figure 2 At this time, the display stand 202 is in an inclined position.

[0069] In one embodiment not shown in the figure, the swing frame 202 can be of other shapes. For example, it can be disc-shaped, with a horizontal frame connected near the edge of the disc to mount the rotary drive mechanism 3.

[0070] In one embodiment, the end of the longitudinal portion 2021 away from the horizontal portion 2022 is connected to the output shaft of the tilting drive mechanism 201, and the output shaft of the tilting drive mechanism 201 is horizontally arranged.

[0071] In this embodiment, since the output shaft of the tilt drive mechanism 201 is set horizontally, it can be ensured that the swing frame 202 swings in a vertical plane perpendicular to the ground.

[0072] Of course, in other alternative embodiments, the output shaft of the tilt drive mechanism 201 may also be tilted at a certain angle so that the swing frame 202 has a tilted tilt position.

[0073] In one embodiment, the rotating driving mechanism 3 is connected with the sample container fixing structure 4 through a clutch mechanism.

[0074] In this embodiment, since the rotating driving mechanism 3 is connected with the sample container fixing structure 4 through the clutch mechanism, when the clutch mechanism is connected with the sample container fixing structure 4, the rotating driving mechanism 3 can drive the sample container fixing structure 4 to rotate the sample container 6, and when the clutch mechanism is separated from the sample container fixing structure 4, the sample container fixing structure 4 no longer rotates with the rotating driving mechanism 3.

[0075] In one embodiment, the clutch mechanism is an electromagnetic clutch.

[0076] In this embodiment, the clutch mechanism is an electromagnetic clutch, which is convenient for controlling the clutch mechanism.

[0077] In one embodiment, the rotating driving mechanism 3 is a brushless motor.

[0078] In this embodiment, the output shaft of the brushless motor is directly connected with the sample container fixing structure 4, and whether the sample container 6 rotates or not can be controlled by turning on or off the brushless motor.

[0079] In one embodiment, the sample container fixing structure 4 is a cup sleeve, and the sample container 6 is adapted to be inserted into the cup sleeve.

[0080] In this embodiment, since the sample container fixing structure 4 is a cup sleeve, the sample container 6 is fixed in the cup sleeve.

[0081] In other alternative embodiments, the sample container fixing structure 4 can include a plurality of clamping jaws to fix the sample container 6.

[0082] In one embodiment, the cup sleeve is adapted to be in interference fit with the sample container 6; or a flexible structure is filled between the cup sleeve and the sample container 6.

[0083] In this embodiment, since the cup sleeve is adapted to be in interference fit with the sample container 6, the sample container 6 is fixed in the cup sleeve without the aid of additional structures, and the fixing of the sample container 6 is simple and convenient. The flexible structure filled between the cup sleeve and the sample container 6 can fix the sample container 6 in the cup sleeve, and can reduce the requirement for the size of the cup sleeve.

[0084] In one embodiment, the cup sleeve is made of soft material.

[0085] In this embodiment, since the cup sleeve is made of soft material, the sample container 6 can be firmly fixed by the elasticity of the cup sleeve itself.

[0086] In one embodiment, the cup sleeve is made of silica gel.

[0087] In an alternative embodiment, the cup sleeve can be made of a hard material, and after the sample container 6 is inserted into the cup sleeve, some flexible structure is filled between the sample container 6 and the cup sleeve to fix the sample container 6.

[0088] In an alternative embodiment, the cup sleeve can include an outer hard layer made of a hard material and an inner soft layer made of a soft material, and the sample container 6 is interference-fitted with the inner soft layer.

[0089] According to the embodiments of the present application, on the other hand, a kind of liquid separation device is also provided, including pipette 5 and the liquid separation device provided in the above embodiments, when swing frame 202 is in the inclined position and sample container fixing structure 4 is fixed with sample container 6, pipette 5 and the bottom of sample container 6 are opposite.

[0090] In this embodiment, when separating supernatant and centrifugal precipitate, pipette 5 can be first moved downward into sample container 6, close to the bottom of sample container 6 and have a certain distance from the bottom of sample container 6, and then start to suck, and a large amount of supernatant in sample container 6 is sucked. Then, swing frame 202 is swung to the inclined position, at this time, sample container fixing structure 4 is vertically inclined, and sample container 6 fixed to sample container fixing structure 4 is inclined, at this time, under the action of gravity, centrifugal precipitate 7 moves to the bottom of sample container 6, and because centrifugal precipitate 7 has certain adhesion or viscosity, it will remain in this position, and then make rotary drive mechanism 3 drive sample container fixing structure 4 to rotate sample container 6 by a certain angle, centrifugal precipitate 7 rotates with sample container 6, as shown in the figure, centrifugal precipitate 7 rotates to the position away from the bottom of sample container 6, at this time, pipette 5 can be extended to the bottom of sample container 6 to suck liquid, so that the supernatant can be completely sucked. Figure 3

[0091] ​In one specific embodiment, the tilting drive mechanism 201 can drive the pendulum 202 to swing, so that the pendulum 202 has a vertical position and a tilted position. When the pendulum 202 is in the vertical position, the sample container fixing structure 4 is set vertically, so the sample container 6 is set vertically. At this time, the pipette 5 can be moved downward into the sample container 6, close to the bottom center of the sample container 6 and at a certain distance from the bottom of the sample container 6, and then aspiration begins to draw a large amount of supernatant from the sample container 6. Then, the tilting drive mechanism 201 drives the pendulum 202 to swing to the tilted position. At this time, the sample container fixing structure 4 is set vertically at an inclination, and the sample container 6 fixed to the sample container fixing structure 4 is set at an inclination. At this time, under the action of gravity, the centrifuged precipitate 7 moves to the bottom of the sample container 6. Since the centrifuged precipitate 7 has a certain degree of adhesion or viscosity, it will remain in this position. Then, the rotation drive mechanism 3 drives the sample container fixing structure 4 to rotate the sample container 6 by a certain angle. The centrifuged precipitate 7 rotates with the sample container 6 and rotates to the position away from the bottom of the sample container 6. At this time, the pipette 5 can be extended to the bottom of the sample container 6 to aspirate the liquid, so that the supernatant can be completely aspirated.

[0092] The mass-liquid separation device of this embodiment can also collect suspensions. Specifically, the supernatant is first aspirated through the pipette 5, leaving the centrifuged precipitate 7, which is, for example, E. coli cells. Then, the centrifuged precipitate 7 is rotated to the bottom of the sample container 6 by the rotation drive mechanism 3. Next, resuspension is added through the pipette 5 to resuspend the centrifuged precipitate 7, thereby generating a suspension. The pipette 5 is then inserted into the bottom of the sample container 6 to aspirate the suspension.

[0093] In one specific embodiment, the pipette 5 is arranged parallel to the fixture 1, and the pipette 5 can move vertically in the up-down direction. Of course, the pipette 5 can also have multiple degrees of freedom.

[0094] Specifically in one embodiment, such as Figure 4 As shown, the pipette 5 is mounted on the end shaft 12 of the robotic arm 11, and the robotic arm 11 and the mounting bracket 1 are mounted on the base 10.

[0095] In one specific embodiment, the end of the pipette 5 is connected to a tubing, which is connected to a collection container. The tubing is equipped with a pump and a valve. The supernatant or suspension drawn from the sample container 6 can be directly collected into the collection container through the tubing. The liquid in the collection container can also be injected into the sample container 6 through the tubing and the pipette 5.

[0096] In one embodiment, the mass-liquid separation device further includes a distance sensor and a controller. The distance sensor is located on the pipette 5, and the controller is communicatively connected to the distance sensor and the rotary drive mechanism 3.

[0097] In this embodiment, when the sample container fixing structure 4 drives the centrifugal precipitate 7 in the sample container 6 to move below the distance sensor, the distance information detected by the distance sensor is obviously different from that without the centrifugal precipitate 7, that is, it can be judged that there is the centrifugal precipitate 7, so that the controller can automatically control the rotation driving mechanism 3 to work, so that the rotation driving mechanism 3 rotates by a certain angle, and the automatic control of the separation of the solid and the liquid can be realized.

[0098] Specifically, the distance sensor can be a laser ranging sensor or an ultrasonic ranging sensor.

[0099] In one embodiment, the solid-liquid separation device further comprises a scanning device and a controller, the scanning device is used for detecting the position of the centrifugal precipitate 7, and the controller is in communication connection with the scanning device and the rotation driving mechanism 3.

[0100] In this embodiment, the position of the centrifugal precipitate 7 can be detected by the scanning device, and then the rotation driving mechanism 3 is controlled to work, so that the automatic control of the separation of the solid and the liquid can be realized.

[0101] Specifically, the scanning device can be an optical scanning mechanism, or an ultrasonic scanning mechanism or a camera, since the color of the centrifugal precipitate 7 is different from that of the supernatant, the position of the centrifugal precipitate 7 can be recognized by scanning.

[0102] Although the embodiments of the present application are described in combination with the drawings, various modifications and variations can be made by those skilled in the art without departing from the spirit and scope of the present application, and such modifications and variations all fall within the scope defined by the present application.

Claims

1. A centrifugation device, characterized in that, The centrifugal device comprises: a fixed frame (1); a swing frame (202), which has at least an inclined position; a rotation driving mechanism (3) arranged on the swing frame (202); a sample container fixing structure (4) connected with the rotation driving mechanism (3) and adapted to rotate under the driving of the rotation driving mechanism (3), the sample container fixing structure (4) being used for fixing a sample container (6), and the sample container fixing structure (4) being arranged in an inclined manner when the swing frame (202) is in the inclined position.

2. The centrifuge device of claim 1, wherein, The swing frame (202) also has a vertical position, and the sample container fixing structure (4) is arranged in a vertical manner when the swing frame (202) is in the vertical position.

3. The centrifuge device of claim 2, wherein, The centrifugal device comprises an inclination driving mechanism (201), and the swing frame (202) can swing relative to the fixed frame (1) under the driving of the inclination driving mechanism (201) so that the swing frame (202) has the inclined position and the vertical position.

4. The centrifuge device of claim 3, wherein, The swing frame (202) is L-shaped and comprises a longitudinal part (2021) and a horizontal part (2022), the longitudinal part (2021) is connected with the inclination driving mechanism (201), and the rotation driving mechanism (3) is arranged on the horizontal part (2022).

5. The centrifuge device of claim 4, wherein, One end of the longitudinal part (2021) away from the horizontal part (2022) is connected with an output shaft of the inclination driving mechanism (201), and the output shaft of the inclination driving mechanism (201) is arranged in a horizontal manner.

6. The centrifugation device according to any one of claims 1 to 5, characterized in that The rotation driving mechanism (3) is connected with the sample container fixing structure (4) through a clutch mechanism.

7. The centrifugation device according to any one of claims 1 to 5, characterized in that The rotation driving mechanism (3) is a brushless motor.

8. The centrifugation device according to any one of claims 1 to 5, characterized in that The sample container fixing structure (4) is a cup sleeve, and the sample container (6) is adapted to be inserted into the cup sleeve.

9. The centrifuge device of claim 8, wherein, The cup sleeve is adapted to be in interference fit with the sample container (6). Alternatively, a flexible structure is filled between the cup sleeve and the sample container (6).

10. The centrifuge device of claim 9, wherein, The cup sleeve is made of a soft material or a hard material.

11. A liquid-gas separation device, characterized by The centrifugal device comprises: a pipette (5); The centrifugal device according to any one of claims 1 to 10, when the swing frame (202) is in the inclined position and the sample container fixing structure (4) is fixed with the sample container (6), the pipette (5) is opposite to the bottom of the sample container (6).

12. The liquid-gas separation device of claim 11, wherein, The centrifugal device further comprises a distance sensor and a controller, the distance sensor is arranged on the pipette (5), and the controller is in communication connection with the distance sensor and the rotation driving mechanism (3).

13. The liquid-gas separation device of claim 11, wherein, The centrifugal device further comprises a scanning device and a controller, the scanning device is used for detecting the position of a centrifugal precipitate (7), and the controller is in communication connection with the scanning device and the rotation driving mechanism (3).

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