Stirring crystallization device for medicine production

By introducing a multi-component collaborative design into the stirred crystallization device for drug production, the problem of uneven drug mixing was solved, resulting in more efficient drug mixing and improved product quality of crystallized products.

CN223818209UActive Publication Date: 2026-01-23HUANGSHI SHIXING PHARMA
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Patent Information

Application Number
CN202422974626.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-04
Publication Date
2026-01-23
Estimated Expiration
2034-12-04

AI Technical Summary

Technical Problem

The existing stirring mechanisms in pharmaceutical crystallization equipment are relatively simple, resulting in poor drug mixing and affecting the efficiency and quality of crystallization.

Method used

The stirring crystallization device employs a multi-component collaborative operation, including a stirring component, a mixing component, and a turbulence-disrupting component. It drives the rotating sleeve and rotating rod through bevel gear meshing, which in turn drives the stirring rod and turbulence-disrupting plate to perform complex rotational movements, ensuring thorough mixing of the drug.

Benefits of technology

It improves the mixing efficiency of drugs and the quality of crystallized products, meets the requirements of various crystallization mixing conditions, and enhances the practicality of the device.

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Abstract

The utility model provides a stirring crystallization device for medicine production. Comprising a crystallizing tank, a stirring assembly is arranged at the top of the crystallizing tank, a mixing assembly is arranged at the top of the stirring assembly, and a turbulent flow assembly is arranged on the inner side of the crystallizing tank. According to the stirring and crystallizing device for medicine production, all parts of the device are arranged in a matched mode, medicines needing to be added are mixed and placed on the inner side of the mixing tank, the mixed medicines are mixed together through rotation of the mixing part, and then the driving motor drives the first bevel gear and the second bevel gear to rotate through meshing of the first bevel gear and the second bevel gear. And the rotating sleeve and the rotating rod are driven to rotate in different directions, so that the rotating sleeve and the rotating rod respectively drive the stirring rods on the surfaces to rotate forwards and backwards in different directions, and the medicines are fully scattered and mixed under the action of the turbulent flow assembly, so that the crystallization efficiency and the quality of crystallized products are improved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to crystallization equipment technical field especially relates to a stirring crystallization device for medicine production. BACKGROUND

[0002] White crystalline or granular medicine, polymorphic structure often appear in medicine production, at present, part of the recrystallization device on the market, crystallization produces, needs manually to scrape the crystallization, when adding medicine is different or medicine adding amount is different, the crystallization device can not satisfy the crystallization mixing condition.

[0003] Chinese patent number: CN 218188012 U discloses a kind of crystallization device for medicine raw material medicine production, the device is equipped with the spoiler mechanism, rotating adjustment plate can drive spoiler plate rotation, the inclination angle of spoiler plate is adjusted, can satisfy the demand of different medicine and drug amount to stirring mixing speed, different medicine is stirred and mixed conveniently crystallization.

[0004] However, the stirring mechanism is relatively single in the process of using the device, which can easily cause poor mixing of the medicine, thus affecting the subsequent crystallization work, and cannot meet the crystallization mixing conditions, greatly reducing the practicability of the device.

[0005] Therefore, it is necessary to provide a stirring crystallization device for medicine production to solve the above technical problems. UTILITY MODEL CONTENT

[0006] The utility model provides a kind of stirring crystallization device for medicine production, solve the process of using the present part device, stirring mechanism is relatively single, easily cause the mixing of medicine to be poor, thus it can very easily affect the subsequent crystallization work, cannot meet the crystallization mixing condition of more, greatly reduce the practicability of device problem.

[0007] To solve the above technical problems, the utility model provides a kind of stirring crystallization device for medicine production, including: crystallization tank, the stirring assembly is arranged at the top of the crystallization tank, the mixing assembly is arranged at the top of the stirring assembly, the spoiler assembly is arranged in the inside of the crystallization tank;

[0008] The stirring assembly comprises a protective cover plate arranged on the top of the crystallization tank, a rotating sleeve is arranged through the inside of the protective cover plate and is rotationally connected with the protective cover plate, a rotating rod is arranged through the inside of the rotating sleeve and is rotationally connected with the rotating sleeve, first bevel gears are fixedly installed on the top ends of the rotating sleeve and the rotating rod, a mounting frame is fixedly installed on the top of the protective cover plate close to the left side, a second bevel gear is rotationally arranged on the surface of the mounting frame, a driving motor for driving the second bevel gear to rotate is fixedly installed on the left side of the mounting frame, and two supporting blocks are sleeved with the outer edges of the rotating sleeve and the rotating rod close to the top ends and are rotationally connected with the rotating sleeve and the rotating rod.

[0009] The mixing assembly comprises a mixing tank arranged on the top of the supporting blocks, a driven rod is rotationally arranged in the inside of the mixing tank, a plurality of mixing elements are fixedly installed on the surface of the driven rod, a rotating cover plate is rotationally arranged on the top of the mixing tank, and the top end of the rotating rod penetrates through the inside of the adjacent first bevel gear and the bottom of the mixing tank in sequence and is fixedly connected with the bottom end of the driven rod.

[0010] Preferably, the bottom ends of the rotating sleeve and the rotating rod extend to the inside of the crystallization tank, the bottom end of the rotating rod is rotationally connected with the bottom of the inside of the crystallization tank, and two groups of stirring rods are arranged on the outer edges of the rotating sleeve and the rotating rod.

[0011] Preferably, the supporting blocks are fixedly installed on the right side of the supporting blocks, the supporting blocks are integrally arranged with the two stirring rods, the bottom end of the supporting blocks is fixedly connected with the top of the protective cover plate, and the right sides of the second bevel gears are meshingly arranged with the surfaces of the adjacent first bevel gears.

[0012] Preferably, the bottom of the mixing tank is communicated with communication pipes close to the four corners, adjusting valves are arranged on the surfaces of the communication pipes close to the centers, and the bottom ends of the communication pipes are communicated with the top of the protective cover plate.

[0013] Preferably, the turbulence assembly comprises turbulence plates rotationally arranged in the inside of the crystallization tank, the number of the turbulence plates is four, rotating seats are sleeved with the outer edges of the rotating sleeve and the rotating rod and are rotationally connected with the rotating sleeve and the rotating rod, the turbulence plates close to one side of the center of the crystallization tank are rotationally connected with the surfaces of the adjacent rotating seats, and adjusting blocks are fixedly installed on the other sides of the turbulence plates.

[0014] Preferably, a fixing seat is fixedly installed on the outer edge of the crystallization tank close to the center, a discharging pipe is fixedly installed on the bottom of the crystallization tank, and a feeding pipe is fixedly installed on the top of the protective cover plate.

[0015] Compared with the related art, the stirring and crystallization device for medicine production has the following advantages

[0016] Advantages:

[0017] This utility model provides a stirring crystallization device for pharmaceutical production. Through the coordinated arrangement of various components of the device, the drugs to be added are placed inside the mixing tank. The mixing components are rotated to mix the drugs together. Then, the drive motor, through the meshing of the first and second bevel gears, drives the rotating sleeve and rotating rod to rotate in different directions. The rotating sleeve and rotating rod respectively drive the stirring rod on the surface to rotate in different directions. With the help of the turbulence component, the drugs are fully dispersed and mixed, increasing the crystallization efficiency and the quality of the crystallized product. Attached Figure Description

[0018] Figure 1 A schematic diagram of a preferred embodiment of the stirring crystallization apparatus for drug production provided by this utility model;

[0019] Figure 2 for Figure 1 A schematic diagram of the structure of the crystallizer shown in the side sectional view;

[0020] Figure 3 for Figure 2 An enlarged structural diagram of point A is shown below;

[0021] Figure 4 for Figure 1 The diagram shows a side sectional view of the mixing tank.

[0022] Labels in the diagram: 10. Crystallization tank; 20. Stirring assembly; 21. Protective cover plate; 22. Rotating sleeve; 23. Rotating rod; 24. First bevel gear; 25. Second bevel gear; 26. Drive motor; 27. Support block; 28. Stirring rod; 30. Mixing assembly; 31. Mixing tank; 32. Driven rod; 33. Mixing component; 34. Rotating cover plate; 35. Connecting pipe; 40. Baffle assembly; 41. Baffle plate; 42. Rotating seat; 43. Adjusting block; 50. Discharge pipe; 60. Feed pipe. Detailed Implementation

[0023] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0024] Please refer to the following: Figure 1 , Figure 2 , Figure 3 , Figure 4 ,in, Figure 1 A schematic diagram of a preferred embodiment of the stirring crystallization apparatus for drug production provided by this utility model; Figure 2 for Figure 1 A schematic diagram of the structure of the crystallizer shown in the side sectional view; Figure 3 for Figure 2 An enlarged structural diagram of point A is shown below; Figure 4For Figure 1 The structural schematic diagram of the side view cross-section of the mixing tank is shown. A stirring crystallization device for pharmaceutical production comprises a crystallization tank 10, a stirring assembly 20 arranged on the top of the crystallization tank 10, a mixing assembly 30 arranged on the top of the stirring assembly 20, and a turbulence assembly 40 arranged inside the crystallization tank 10.

[0025] The stirring assembly 20 comprises a protective cover plate 21 arranged on the top of the crystallization tank 10, a rotating sleeve 22 arranged through the inside of the protective cover plate 21 and rotationally connected thereto, a rotating rod 23 arranged through the inside of the rotating sleeve 22 and rotationally connected thereto, and a first bevel gear 24 fixedly installed on the top end of the rotating sleeve 22 and the rotating rod 23. A mounting bracket is fixedly installed on the top of the protective cover plate 21 near the left side, a second bevel gear 25 is rotationally arranged on the surface of the mounting bracket, a driving motor 26 is fixedly installed on the left side of the mounting bracket to drive the second bevel gear 25 to rotate, and two support blocks 27 are sleeved on the outer edge of the rotating rod 23 near the top end and rotationally connected thereto.

[0026] Liquid is added into the crystallization tank 10 through the feed pipe 60, the driving motor 26 is arranged through the meshing of the first bevel gear 24 and the second bevel gear 25 to drive the rotating sleeve 22 and the rotating rod 23 to rotate in different directions, so that the rotating sleeve 22 and the rotating rod 23 drive the stirring rods 28 on the surface to rotate in different directions, and cooperate with the action of the turbulence assembly 40 to fully disperse and mix the medicine, thereby increasing the crystallization efficiency and the quality of the crystallization product.

[0027] The mixing assembly 30 comprises a mixing tank 31 arranged on the top of the support block 27, a driven rod 32 rotationally arranged inside the mixing tank 31, a plurality of mixing pieces 33 fixedly installed on the surface of the driven rod 32, and a rotating cover plate 34 rotationally arranged on the top of the mixing tank 31. The top end of the rotating rod 23 successively penetrates the inside of the adjacent first bevel gear 24 and the bottom of the mixing tank 31, and is fixedly connected with the bottom end of the driven rod 32.

[0028] During use, the rotating cover plate 34 is opened, and the mixed medicine to be added is placed inside the mixing tank 31, the driving motor 26 starts to work, the driven rod 32 is driven to rotate through the meshing of the first bevel gear 24 and the second bevel gear 25, and the mixed medicine is mixed together through the rotation of the mixing pieces 33, after completion, the communication pipe 35 is opened through the adjusting valve, and the medicine falls into the inside of the crystallization tank 10.

[0029] The bottom end of the rotating sleeve 22 and the bottom end of the rotating rod 23 both extend to the inside of the crystallization tank 10, the bottom end of the rotating rod 23 is rotationally connected with the bottom of the inside of the crystallization tank 10, and two groups of stirring rods 28 are arranged on the outer edge of the rotating sleeve 22 and the rotating rod 23.

[0030] The support block 27 is fixedly installed with a support frame on the right side, the support frame is integrally arranged with the two stirring rods 28, the bottom end of the support frame is fixedly connected with the top of the protective cover plate 21, and the right side of the second bevel gear 25 is meshingly arranged with the surface of the adjacent first bevel gear 24.

[0031] The bottom of the mixing tank 31 is communicatively provided with a communication pipe 35 near the four corners, the surface of the communication pipe 35 is provided with an adjusting valve near the center, and the bottom end of the communication pipe 35 is communicatively provided on the top of the protective cover plate 21.

[0032] The turbulence assembly 40 comprises turbulence plates 41 rotatably arranged on the inner side of the crystallization tank 10, the number of the turbulence plates 41 is four, the outer edges of the rotating sleeve 22 and the rotating rod 23 are both sleeved with rotating seats 42 and are rotatably connected with the rotating seats 42, the side of the turbulence plate 41 close to the center of the crystallization tank 10 is rotatably connected with the surface of the adjacent rotating seat 42, and the other side of the turbulence plate 41 is fixedly installed with an adjusting block 43.

[0033] The outer edge of the crystallization tank 10 close to the center is fixedly installed with a fixed seat, the bottom of the crystallization tank 10 is fixedly installed with a discharge pipe 50, and the top of the protective cover plate 21 is fixedly installed with a feeding pipe 60.

[0034] The working principle of the stirring and crystallization device for medicine production is as follows:

[0035] First step: in the process of use, the rotating cover plate 34 is opened, the mixed medicine to be added is placed in the inner side of the mixing tank 31, the driving motor 26 starts to work, the driven rod 32 is driven to rotate through the meshing arrangement of the first bevel gear 24 and the second bevel gear 25, the mixed medicine is mixed together through the rotation of the mixing piece 33, after completion, the communication pipe 35 is opened through the adjusting valve, and the medicine falls into the inner side of the crystallization tank 10;

[0036] Second step: the liquid is added into the crystallization tank 10 through the feeding pipe 60, the driving motor 26 drives the rotating sleeve 22 and the rotating rod 23 to rotate in different directions through the meshing arrangement of the first bevel gear 24 and the second bevel gear 25, the stirring rod 28 on the surface of the rotating sleeve 22 and the rotating rod 23 is driven to rotate in different directions, and the medicine is fully dispersed and mixed through the action of the turbulence assembly 40, so that the crystallization efficiency and the quality of the crystallization product are improved.

[0037] Compared with the related art, the stirring and crystallization device for medicine production has the following advantages

[0038] Beneficial effects:

[0039] Through the cooperation of each part of the device, the mixed medicine to be added is placed in the mixing tank 31, and the mixed medicine is mixed together through the rotation of the mixing piece 33. Then the motor 26 is driven to rotate the rotating sleeve 22 and the rotating rod 23 in different directions through the meshing of the first bevel gear 24 and the second bevel gear 25, so that the rotating sleeve 22 and the rotating rod 23 drive the stirring rods 28 on the surfaces to rotate in different directions, and cooperate with the action of the turbulence assembly 40 to fully disperse and mix the medicine, increase the crystallization efficiency and the quality of the crystallization product.

[0040] The above is only an embodiment of the present application, and does not limit the patent range of the present application. Any equivalent structure or equivalent process conversion, or direct or indirect application in other related technical fields, which is made by using the content of the present application specification and drawings, is also included in the patent protection range of the present application.

Claims

1. A stirring crystallization apparatus for pharmaceutical production, characterized in that, include: A crystallization tank (10) is provided with a stirring assembly (20) on the top of the crystallization tank (10), a mixing assembly (30) is provided on the top of the stirring assembly (20), and a turbulence assembly (40) is provided inside the crystallization tank (10). The stirring assembly (20) includes a protective cover plate (21) disposed on the top of the crystallizing tank (10). A rotating sleeve (22) is provided through the inner side of the protective cover plate (21) and is rotatably connected to it. A rotating rod (23) is provided through the inner side of the rotating sleeve (22) and is rotatably connected to it. A first bevel gear (24) is fixedly installed at the top of both the rotating sleeve (22) and the rotating rod (23). A mounting bracket is fixedly installed on the top of the protective cover plate (21) near the left side. A second bevel gear (25) is rotatably disposed on the surface of the mounting bracket. A drive motor (26) for driving the second bevel gear (25) to rotate is fixedly installed on the left side of the mounting bracket. Two support blocks (27) are sleeved on the outer edge of the rotating rod (23) near the top and are rotatably connected to it. The mixing assembly (30) includes a mixing tank (31) disposed on the top of the support block (27). A driven rod (32) is rotatably disposed inside the mixing tank (31). A plurality of mixing components (33) are fixedly mounted on the surface of the driven rod (32). A rotating cover plate (34) is rotatably disposed on the top of the mixing tank (31). The top end of the rotating rod (23) passes through the inner side of the adjacent first bevel gear (24) and the bottom of the mixing tank (31) in sequence, and is fixedly connected to the bottom end of the driven rod (32).

2. The stirred crystallization apparatus for pharmaceutical production according to claim 1, characterized in that, The bottom ends of the rotating sleeve (22) and the rotating rod (23) both extend to the inside of the crystallization tank (10). The bottom end of the rotating rod (23) is rotatably connected to the bottom of the inside of the crystallization tank (10). Two sets of stirring rods (28) are provided on the outer edges of the rotating sleeve (22) and the rotating rod (23). The top and bottom of the stirring rods (28) are fixedly equipped with baffle rods.

3. The stirred crystallization apparatus for pharmaceutical production according to claim 1, characterized in that, The support block (27) is fixedly installed with a support frame on the right side. The support frame and the two stirring rods (28) are integrated. The bottom end of the support frame is fixedly connected to the top of the protective cover plate (21). The right side of the second bevel gear (25) is meshed with the surface of the adjacent first bevel gear (24).

4. The stirred crystallizing apparatus for pharmaceutical production according to claim 1, characterized in that, The mixing tank (31) is connected to the four corners of the bottom by a connecting pipe (35), and the surface of the connecting pipe (35) is provided with a regulating valve near the center. The bottom end of the connecting pipe (35) is connected to the top of the protective cover plate (21).

5. The stirred crystallizing apparatus for pharmaceutical production according to claim 1, characterized in that, The turbulence assembly (40) includes a turbulence plate (41) rotatably disposed inside the crystallization tank (10), and there are four turbulence plates (41). The outer edges of the rotating sleeve (22) and the rotating rod (23) are fitted with rotating seats (42) and rotatably connected to them. The side of the turbulence plate (41) near the center of the crystallization tank (10) is rotatably connected to the surface of the adjacent rotating seat (42). An adjusting block (43) is fixedly installed on the other side of the turbulence plate (41).

6. The stirred crystallization apparatus for pharmaceutical production according to claim 1, characterized in that, A fixed base is fixedly installed on the outer edge of the crystallizer (10) near the center, a discharge pipe (50) is fixedly installed at the bottom of the crystallizer (10), and a feed pipe (60) is fixedly installed on the top of the protective cover (21).

Citation Information

Patent Citations

  • Crystallization device for medicinal raw material medicine production

    CN218188012U