Rapid mononuclear cell separation tube capable of being easily filled with partition plate

Abstract

The utility model discloses a rapid mononuclear cell separation tube capable of being easily filled with a partition plate, and belongs to the technical field of cell separation, the rapid mononuclear cell separation tube comprises a centrifugal tube and the partition plate provided with three supporting legs, the partition plate is provided with a peripheral through hole, and the side wall of the bottom in the centrifugal tube is provided with a flange surrounding the axis of the centrifugal tube; a supporting cover is arranged at the open end of the centrifugal tube, a supporting rod moving in the axis direction of the centrifugal tube is arranged on the supporting cover, and a tray used for supporting the partition plate and driving the partition plate to move relative to the centrifugal tube in parallel is arranged at the end, located in the centrifugal tube, of the supporting rod. The tray is provided with a protrusion matched with the peripheral through hole, the protrusion is provided with an air hole which is the same as the peripheral through hole and penetrates through the tray, and the device has the advantages that the partition plate can be rapidly and accurately filled under the condition that it is guaranteed that the partition plate is relatively parallel to the inner diameter of the centrifugal tube, the filling efficiency is greatly improved, and the partition plate and the centrifugal tube are firmly fixed.

Description

Technical Field

[0001] This application relates to the field of cell separation technology, and more specifically to a rapid mononuclear cell separation tube with an easily fillable septum. Background Technology

[0002] The rapid mononuclear cell separation tube is a simple separation device that facilitates the extraction of mononuclear cells from blood. It consists of a regular centrifuge tube and a partition placed inside the centrifuge tube. The partition can isolate the separation solution from the blood sample, making the addition of blood sample and the collection of the white film layer after centrifugation more convenient.

[0003] Currently, Chinese utility model patent CN205556662U discloses a rapid mononuclear cell separation tube, including a centrifuge tube. The centrifuge tube has an opening at the top and a closed bottom. The top of the centrifuge tube has a cap for closing the opening. The centrifuge tube has a separation support inside that divides the centrifuge tube into upper and lower parts. The separation support includes a disc and several legs. The legs are located on the edge of the disc and are used to support the disc. The legs are also connected to the centrifuge tube. The disc has a central through hole at its center. The legs have locking holes. The centrifuge tube has a protruding post on its inner side that cooperates with the locking holes.

[0004] In existing technologies similar to the rapid mononuclear cell separation tubes described above, the septum (i.e., the separation scaffold) requires careful manual loading and multiple adjustments to ensure correct placement during the filling process, leading to low efficiency. Furthermore, if the septum is misaligned with the connector, pressing it can cause it to tilt, resulting in low product yield. Therefore, a device is needed to improve production efficiency and product yield. Utility Model Content

[0005] To address the shortcomings of existing technologies, the purpose of this invention is to provide a rapid mononuclear cell separation tube with an easily filled septum. Its advantage lies in the ability to quickly and accurately fill the septum while ensuring that the septum is relatively parallel to the inner diameter of the centrifuge tube, thereby greatly improving filling efficiency and firmly fixing the septum to the centrifuge tube.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a rapid mononuclear cell separation tube with an easily filled partition, comprising a centrifuge tube and a partition with three legs. The partition has an outer peripheral through hole. The bottom side wall of the centrifuge tube has a flange that surrounds its axis. The flange has a insertion groove that mates with the corresponding legs. One end of the centrifuge tube opening has a support cover. The support cover has a support rod that moves along the centrifuge tube axis. One end of the support rod inside the centrifuge tube has a tray for supporting the partition and driving the partition to move relatively parallel to the centrifuge tube. The tray has a protrusion that mates with the outer peripheral through hole. The protrusion has a vent hole that is the same as the outer peripheral through hole and penetrates the tray.

[0007] By adopting the above technical solution, when it is necessary to install the partition into the centrifuge tube, the partition can be placed upside down on the tray, and the protrusion on the tray can be engaged with the outer peripheral through hole. Then, the centrifuge tube opening is placed vertically downward, and the partition is inserted into the centrifuge tube by the tray. After the support cover abuts against the centrifuge tube opening, the support rod drives the tray to support the partition to move vertically upward. Rotating the support rod can drive the partition to rotate. After the partition's support legs are aligned with the insertion slots on the flange, the tray continues to drive the partition to rise, and finally the support legs are engaged with the insertion slots. When the tray drives the partition to move inside the centrifuge tube, the gas between the partition and the centrifuge tube is discharged through the outer peripheral through hole and the vent hole. The protrusion engages with the outer peripheral through hole, which can effectively enable the tray to drive the partition to rotate inside the centrifuge tube, facilitating the adjustment of the partition's position.

[0008] In summary, the above-mentioned design, including the support cover, support rod, tray, and protrusions, facilitates the upward rotation of the partition. Gas between the partition and the centrifuge tube is discharged through the outer peripheral through-hole and vent. After the partition's support legs abut against the centrifuge tube flange, the tray drives the partition to rotate. Once the support legs align with the insertion slot, they are directly inserted, ensuring that the partition and the centrifuge tube's internal diameter are relatively parallel. This allows for rapid and accurate partition filling, significantly improving filling efficiency and firmly securing the partition to the centrifuge tube.

[0009] The present invention is further configured such that: the lower end of the support leg is arc-shaped, the insertion groove is fitted into the support leg, and the edge of the insertion groove is rounded.

[0010] By adopting the above technical solution, the lower end of the support leg is set with an arc, which can play a transition role in the process of inserting the support leg into the insertion slot, making it easier for the support leg to be inserted into the insertion slot.

[0011] The present invention is further configured such that: the side wall of the insertion slot is provided with a limiting protrusion, and the support leg is provided with a limiting hole that cooperates with the limiting protrusion.

[0012] By adopting the above technical solution, the limiting protrusion and the limiting hole can firmly fix the support leg in the insertion groove.

[0013] The present invention is further configured such that: a limiting sleeve is provided at one end of the support cover facing the partition, which is slidably connected to the support rod, and a support frame is provided on the limiting sleeve that is connected to the support cover.

[0014] By adopting the above technical solution, the setting of the limiting sleeve and the support frame can make the movement of the support rod more stable, thereby making the installation of the partition more convenient.

[0015] The present invention is further configured such that: the outer wall of the centrifuge tube opening is provided with a snap-fit ​​groove penetrating the end face of its opening, and the support cover is provided with a snap-fit ​​strip that cooperates with the snap-fit ​​groove.

[0016] By adopting the above technical solution, the design of the snap-fit ​​strip and snap-fit ​​groove can effectively prevent the support cover and centrifuge tube from rotating.

[0017] The present invention is further configured such that a force-applying block is provided at the end of the support rod away from the partition.

[0018] In summary, this utility model has the following advantages:

[0019] 1. The design, including the support cover, support rod, tray, and protrusions, facilitates the upward rotation of the partition. Gas between the partition and the centrifuge tube is discharged through the outer peripheral through-hole and vent. After the partition legs abut against the centrifuge tube flange, the tray drives the partition to rotate. Once the legs are aligned with the insertion slot, they can be directly inserted and fitted. This ensures that the partition and the inner diameter of the centrifuge tube are relatively parallel, allowing for quick and accurate partition filling, greatly improving filling efficiency and firmly fixing the partition and centrifuge tube.

[0020] 2. By setting limit protrusions and limit holes, the support legs can be firmly fixed in the insertion slot.

[0021] 3. By setting the snap-fit ​​strip and snap-fit ​​groove, the rotation of the support cover and centrifuge tube can be effectively prevented. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the overall structure of this embodiment;

[0023] Figure 2 This is a cross-sectional structural diagram of this embodiment;

[0024] Figure 3 yes Figure 2 A magnified structural diagram of B in the diagram;

[0025] Figure 4 yes Figure 2 A magnified structural diagram of A in the middle.

[0026] Explanation of reference numerals in the attached drawings: 1. Centrifuge tube; 2. Support leg; 3. Partition; 4. Outer peripheral through hole; 5. Flange; 6. Insertion groove; 7. Support cover; 8. Support rod; 9. Tray; 10. Protrusion; 11. Vent hole; 12. Force application block; 13. Limiting protrusion; 14. Limiting hole; 15. Limiting sleeve; 16. Support frame; 17. Snap-fit ​​groove; 18. Snap-fit ​​strip. Detailed Implementation

[0027] The present invention will be further described in detail below with reference to the accompanying drawings.

[0028] A rapid mononuclear cell separation tube with an easily fillable septum 3, such as Figure 1 , 2 As shown in Figure 4, the centrifuge tube 1 includes a partition 3 with three extended legs 2. The partition 3 has three peripheral through holes 4. The bottom side wall of the centrifuge tube 1 has a flange 5 extending along its axis. The flange 5 has a insertion groove 6 that mates with the corresponding legs 2. One end of the centrifuge tube 1 is fitted with a support cover 7 identical to the outside. A support rod 8 that moves along the axis of the centrifuge tube 1 is slidably mounted on the support cover 7. One end of the support rod 8 inside the centrifuge tube 1 is fixed with a tray 9 for supporting the partition 3 and driving the partition 3 to move relatively parallel to the centrifuge tube 1. The tray 9 has a protrusion 10 that engages with the peripheral through holes 4. The protrusion 10 has a vent hole 11 identical to the peripheral through holes 4 and passes through the tray 9. The end of the support rod 8 away from the partition 3 is fixed with a force-applying block 12.

[0029] like Figure 2 , 3 As shown, the lower end of the support leg 2 is rounded, and the insertion groove 6 fits into the support leg 2. The edge of the insertion groove 6 is rounded, which can play a transition role when the support leg 2 is inserted into the insertion groove 6, making it easier for the support leg 2 to be inserted into the insertion groove 6.

[0030] like Figure 3 As shown, the side wall of the insertion groove 6 extends with a limiting protrusion 1310, and the support leg 2 is provided with a limiting hole 14 that matches the limiting protrusion 1310, so that the support leg 2 can be firmly fixed in the insertion groove 6.

[0031] like Figure 2 As shown, a limiting sleeve 15 that is slidably connected to the support rod 8 is installed on one end of the support cover 7 facing the partition 3. A support frame 16 that is connected to the support cover 7 is fixed on the limiting sleeve 15, which can make the support rod 8 move more smoothly, thereby making the installation of the partition 3 more convenient.

[0032] like Figure 1As shown, the outer wall of the centrifuge tube 1 opening is provided with a snap-fit ​​groove 17 that penetrates the end face of its opening, and the support cover 7 extends with a snap-fit ​​strip 18 that cooperates with the snap-fit ​​groove 17, which can effectively prevent the support cover 7 and the centrifuge tube 1 from rotating.

[0033] The working process and beneficial effects of this utility model are as follows: When it is necessary to install the partition 3 into the centrifuge tube 1, first, the end of the tray 9 with the protrusion 10 is placed vertically upwards. Then, the partition 3 can be inverted onto the tray 9, so that the protrusion 10 on the tray 9 is engaged with the outer peripheral through hole 4. Next, the opening of the centrifuge tube 1 is placed vertically downwards, and the partition 3 is driven into the centrifuge tube 1 by the tray 9. After the support cover 7 abuts against the opening of the centrifuge tube 1, the support rod 8 drives the tray 9 to support the partition 3 to move vertically upwards. Rotating the support rod 8 can drive the partition 3 to rotate. After the support leg 2 of the partition 3 aligns with the insertion groove 6 on the flange 5, the tray 9 continues to drive the partition 3 to rise, and finally the support leg 2 and the insertion groove 6 are engaged. When the tray 9 drives the partition 3 to move in the centrifuge tube 1, the gas between the partition 3 and the centrifuge tube 1 is discharged through the outer peripheral through hole 4 and the vent hole 11. The protrusion 10 is engaged with the outer peripheral through hole 4, which can effectively drive the tray 9 to drive the partition 3 to rotate in the centrifuge tube 1, which facilitates the position adjustment of the partition 3.

[0034] In summary, the above-mentioned arrangement of the support cover 7, support rod 8, tray 9, and protrusion 10 facilitates the upward rotation of the partition 3. The gas between the partition 3 and the centrifuge tube 1 is discharged through the outer peripheral through hole 4 and the vent hole 11. After the support leg 2 of the partition 3 abuts against the flange 5 of the centrifuge tube 1, the partition 3 is rotated by the tray 9. After the support leg 2 is aligned with the insertion slot 6, it is directly inserted and fitted. This achieves the goal of quickly and accurately filling the partition 3 while ensuring that the internal diameter of the partition 3 and the centrifuge tube 1 are relatively parallel, greatly improving the filling efficiency and firmly fixing the partition 3 and the centrifuge tube 1.

[0035] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the design concept of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A rapid mononuclear cell separation tube with an easily fillable septum (3), comprising a centrifuge tube (1) and a septum (3) provided with three supports (2), wherein the septum (3) is provided with an outer peripheral through hole (4), characterized in that: The centrifuge tube (1) has a flange (5) that surrounds its axis on the bottom side wall inside. The flange (5) has a insertion groove (6) that matches the corresponding support leg (2). The centrifuge tube (1) has a support cover (7) at one end of its opening. The support cover (7) has a support rod (8) that moves along the axis of the centrifuge tube (1). The support rod (8) inside the centrifuge tube (1) has a tray (9) for supporting the partition (3) and driving the partition (3) to move relatively parallel to the centrifuge tube (1). The tray (9) has a protrusion (10) that matches the outer peripheral through hole (4). The protrusion (10) has a vent hole (11) that is the same as the outer peripheral through hole (4) and penetrates the tray (9).

2. The rapid mononuclear cell separation tube with an easily fillable septum (3) according to claim 1, characterized in that: The lower end of the support leg (2) is rounded, the insertion groove (6) is fitted into the support leg (2), and the edge of the insertion groove (6) is rounded.

3. The rapid mononuclear cell separation tube with an easily fillable septum (3) according to claim 2, characterized in that: The side wall of the insertion slot (6) is provided with limiting protrusions (13) (10), and the support leg (2) is provided with limiting holes (14) that cooperate with the limiting protrusions (13) (10).

4. The rapid mononuclear cell separation tube with an easily fillable septum (3) according to claim 1, characterized in that: The support cover (7) is provided with a limiting sleeve (15) that slides and connects with the support rod (8) at one end facing the partition (3), and a support frame (16) that connects with the support cover (7) is provided on the limiting sleeve (15).

5. A rapid mononuclear cell separation tube with an easily fillable septum (3) according to claim 1, characterized in that: The centrifuge tube (1) has a snap-fit ​​groove (17) that penetrates its opening end face on the outer wall of the opening, and the support cover (7) has a snap-fit ​​strip (18) that cooperates with the snap-fit ​​groove (17).

6. The rapid mononuclear cell separation tube with an easily fillable septum (3) according to claim 1, characterized in that: A force-applying block (12) is provided at the end of the support rod (8) away from the partition (3).

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