Homogenizing and stirring equipment

By using a homogenizing and stirring device with a flow guide and stirring fan during the preparation of the medicine solution, the problem of the difficulty in mixing solid substances in the medicine solution was solved, and efficient and uniform mixing of the medicine solution was achieved, thereby improving the quality stability and safety of the medicine solution.

CN223874858UActive Publication Date: 2026-02-06LUOYANG HUIDE BIO ENG CO LTD
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Patent Information

Application Number
CN202520461960.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-17
Publication Date
2026-02-06
Estimated Expiration
2035-03-17

AI Technical Summary

Technical Problem

Solid substances in a drug solution are not easily bound and mixed, resulting in low homogenization stirring efficiency, which affects the stability and safety of the drug solution. This is especially true for drugs with high requirements for mixing uniformity, such as injections, which may lead to serious quality problems.

Method used

A homogenizing and mixing device is adopted, which includes a vertically arranged container, a homogenizing component and a flow guide hood. The bottom of the flow guide hood is fixed to the bottom wall of the container by a support column. The outer periphery of the flow guide hood is provided with sieve holes. Combined with a stirring fan and a homogenizer, the flow guide hood is used to restrict solid substances, and the rotation of the stirring fan and the homogenizer achieves rapid crushing and uniform distribution. The positioning column, the baffle strip and the rough layer are used to improve the homogenization efficiency of the medicine solution.

Benefits of technology

It achieves rapid and uniform crushing and distribution of solid substances in the medicinal solution, improves the homogenization efficiency and quality stability of the medicinal solution, reduces the stratification and sedimentation of the medicinal solution, and ensures efficient and uniform mixing of the medicinal solution.

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Abstract

The utility model discloses a homogenizing and stirring device which is provided with a vertically arranged containing cylinder, a homogenizing assembly arranged in the containing cylinder and a flow guide cover arranged outside the homogenizing assembly in a covering mode, and the bottom of the flow guide cover is fixedly connected with the bottom wall of the containing cylinder through a plurality of supporting columns. The homogenizing assembly comprises a driving motor arranged on the upper side face of the containing cylinder, the driving motor is in transmission with a driving shaft penetrating into the containing cylinder, and the driving shaft drives a stirring fan and a homogenizer which are arranged in the containing cylinder; the flow guide cover is a conical barrel with sieve holes in the periphery, the narrow opening end of the flow guide cover is arranged downwards, and a liquid inlet allowing liquid medicine to be poured in is formed in the position, corresponding to the flaring end of the flow guide cover, of the containing barrel, so that after the liquid medicine is poured into the containing barrel from the liquid inlet, the liquid medicine enters the flow guide cover firstly and then is diffused to the inner wall of the containing barrel through the sieve holes. The problems that in the prior art, solid matter in liquid medicine is not prone to being bound and mixed, and then the liquid medicine homogenizing and stirring efficiency is affected are solved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of liquid medicine preparation, and specifically relates to a homogenizing stirring equipment. BACKGROUND

[0002] In the pharmaceutical field, the preparation process of liquid medicine is crucial, and homogenizing stirring is one of the key links of liquid medicine preparation. The purpose of homogenizing stirring is to uniformly mix various components in the liquid medicine, ensuring the quality stability and consistency of drug efficacy. Especially for liquid medicine containing solid substances, uniform mixing can better disperse the effective components of the medicine, improving the bioavailability and therapeutic effect of the medicine.

[0003] Currently, in the homogenizing stirring process of liquid medicine, homogenizing machines and stirring blades are commonly used to achieve mixing operation. However, it is found in actual production that the solid substances in the liquid medicine are not easy to be bound. This is because the physical properties (such as density, shape, particle size, etc.) of solid substances are greatly different from the liquid components in the liquid medicine, making it difficult for solid substances to be fully mixed with liquid under the stirring action of homogenizing machines and stirring blades. On the one hand, solid substances may agglomerate during stirring, forming larger particle groups that are difficult to be further dispersed; on the other hand, due to the limitations of the action mode and flow field characteristics of the stirring equipment, solid substances may not be effectively captured and driven, resulting in uneven distribution in the liquid medicine.

[0004] This situation of solid substances not being easy to be bound and mixed directly affects the efficiency of homogenizing stirring. Inefficient homogenizing stirring not only prolongs the production cycle and increases production costs, but also may lead to unstable liquid medicine quality, affecting the safety and effectiveness of the medicine. In addition, for some liquid medicines with high requirements for mixing uniformity, such as injections, insufficient homogenizing stirring may cause serious quality problems, even endangering the health of patients, therefore, how to solve the problem of solid substances in the liquid medicine not being easy to be bound and mixed and improve the efficiency of homogenizing stirring is an important issue to be solved in the field of liquid medicine preparation. INVENTION CONTENTS

[0005] The purpose of the utility model is to solve the problem of solid substances in the liquid medicine not being easy to be bound and mixed in the prior art, thereby affecting the efficiency of homogenizing stirring of liquid medicine, and to provide a homogenizing stirring equipment.

[0006] To solve the above technical problems, the utility model adopts the technical scheme of a homogenizing stirring equipment, which has a vertically arranged holding cylinder, a homogenizing assembly arranged in the holding cylinder, and a fairing covering the homogenizing assembly, the bottom of the fairing being fixedly connected with the bottom wall of the holding cylinder through multiple support columns.

[0007] The homogenizing assembly comprises a driving motor arranged on the upper side of the containing cylinder, a driving shaft penetrating into the containing cylinder and driven by the driving motor, and a stirring fan and a homogenizer arranged in the containing cylinder and driven by the driving shaft;

[0008] The flow guide cover is a conical cylinder with sieve holes arranged on the outer periphery, the narrow end of the flow guide cover is arranged downward, and the containing cylinder is provided with a liquid inlet for pouring the medicinal liquid at the flared end of the flow guide cover, so that the medicinal liquid poured into the containing cylinder from the liquid inlet first enters the inside of the flow guide cover and then diffuses to the inner wall of the containing cylinder through the sieve holes.

[0009] As a further optimization of the homogenizing stirring equipment, three positioning columns are arranged between the homogenizer and the inner wall of the upper side of the containing cylinder.

[0010] As a further optimization of the homogenizing stirring equipment, a plurality of turbulence strips are uniformly arranged on the outer periphery of the positioning column, and the turbulence strips are continuously arranged along the axial direction of the positioning column.

[0011] As a further optimization of the homogenizing stirring equipment, a rough layer for obstructing the flow of the medicinal liquid is arranged on the inner wall of the containing cylinder.

[0012] As a further optimization of the homogenizing stirring equipment, the stirring fan is correspondingly arranged at the middle part of the flow guide cover.

[0013] As a further optimization of the homogenizing stirring equipment, the homogenizer is correspondingly arranged at the narrow end of the flow guide cover, so that the medicinal liquid circulates into the flow guide cover from the bottom and is discharged from the sieve holes of the flow guide cover.

[0014] As a further optimization of the homogenizing stirring equipment, an opening and closing cover for opening and closing the liquid inlet is rotatably arranged on the containing cylinder, and a clamping handle for clamping with the driving motor is arranged on the opening and closing cover.

[0015] As a further optimization of the homogenizing stirring equipment, a plurality of supporting legs are uniformly arranged on the bottom surface of the containing cylinder.

[0016] Compared with the prior art, the homogenizing stirring equipment has the following beneficial effects:

[0017] The flow guide cover is arranged to limit the fixed substance, i.e. the solute, in the poured medicinal liquid to the vicinity of the stirring fan and the homogenizer, so that the solute in the medicinal liquid can be finely crushed quickly when the stirring fan and the homogenizer are running, and the finely crushed solute is uniformly distributed in the medicinal liquid, i.e. the high-efficiency and high-quality homogenization of the medicinal liquid is realized. BRIEF DESCRIPTION OF DRAWINGS

[0018] Figure 1A cross section structure schematic view of the utility model;

[0019] Figure 2 A structure schematic view of the utility model in closed state;

[0020] Figure 3 A structure schematic view of the utility model in open state;

[0021] Marked in the drawing: 1, holding piece; 101, support foot; 102, holding cylinder; 103, liquid inlet; 104, open and close cover; 105, clamping handle; 106, rough layer; 2, homogenizing assembly; 201, drive motor; 202, drive shaft; 203, stirring fan; 204, positioning column; 205, spoiler strip; 206, homogenizer; 3, flow guide cover; 4, support column. DETAILED DESCRIPTION

[0022] In order to better understand the utility model, the contents of the utility model are further illustrated below in combination with examples, but the contents of the utility model are not limited to the following examples.

[0023] As Figure 2 and Figure 3 shown, a homogenizing stirring equipment, unlike the prior art, has a holding piece 1 for holding liquid medicine, specifically, the holding piece 1 includes a vertically arranged holding cylinder 102, the bottom of the holding cylinder 102 is provided with a support foot 101 to enable the holding cylinder 102 to be stably placed, the top of the holding cylinder 102 is provided with a liquid inlet 103, the liquid inlet 103 can pour liquid medicine for storage, and then cooperate with a homogenizing assembly 2 arranged on the holding cylinder 102 to stir, to homogenize the liquid medicine, so as to maintain the quality stability and consistency of the liquid medicine by the staff, the homogenizing assembly 2 includes a drive motor 201 fixedly arranged at the center of the top of the holding cylinder 102, the drive motor 201 drives a drive shaft 202 penetrating through the top surface of the holding cylinder 102 and arranged in the holding cylinder 102, the drive shaft 202 is provided with a stirring fan 203, the stirring fan 203 can rotate at high speed with the drive shaft 202 driven by the drive motor 201, and then the stirring fan 203 will mix and stir the liquid medicine in the holding cylinder 102, to homogenize the liquid medicine. Specifically, the rotation of the stirring fan 203 mainly makes the liquid medicine produce macro flow through the pushing action of the blade, and then form a large range of liquid flow circulation, and through this stirring, the dissolution of solute in the liquid medicine can be accelerated, the heat transfer and mass exchange between each part of the liquid medicine are promoted, and the solid particles in the liquid medicine can also be prevented from settling at the bottom of the container.

[0024] The liquid inlet 103 is provided with an openable cover 104 covering the liquid inlet 103, and the openable cover 104 is hinged to the liquid inlet 103 corresponding to the containing cylinder 102, so as to close or open the containing cylinder 102 for the staff to close the containing cylinder 102 for stirring and open the containing cylinder 102 for pouring the liquid medicine, and the openable cover 104 is provided with two clamping handles 105 on the side away from the containing cylinder 102, so as to facilitate the staff to pull and rotate the openable cover 104 to open or close the liquid inlet 103, and the clamping handle 105 can be clamped with a driving motor 201 arranged on the top of the containing cylinder 102, so as to position and keep the openable cover 104 in the open state of the containing cylinder 102, thereby facilitating the staff to pour the liquid medicine to be homogenized into the containing cylinder 102 for homogenization treatment.

[0025] Unlike the prior art, the end of the drive shaft 202 away from the drive motor 201 is drivingly connected with the homogenizer 206, and the homogenizer 206 is connected with the three positioning columns 204 arranged on the inner wall of the top of the containing cylinder 102. The three positioning columns 204 can assist in maintaining the relative position of the homogenizer 206, so as to maintain the relative position of the homogenizer 206 during the rotation of the drive motor 201 driving the homogenizer 206, so that the homogenizer 206 stably homogenizes the liquid medicine. Specifically, the homogenizer 206 is a rotary cutting type homogenizer 206. When the drive motor 201 drives the drive shaft 202 to rotate, the drive shaft 202 drives the inner blade and inner rotor arranged in the homogenizer 206 to rotate. The rotation of the inner blade generates suction to suck the liquid medicine in the containing cylinder 102 into the homogenizer 206. Then the liquid medicine will flow to the inner blade with the tooth-shaped cutting knife arranged on the circumference of the inner blade through the outer cover with holes. The inner blade cuts the liquid medicine between the inner rotor and the outer cover multiple times at high speed to realize homogenization. That is, the homogenizer 206 will apply high shear force, high frequency vibration and cavitation effect to the liquid medicine during rotation, thereby enabling different phases of substances in the liquid medicine to be fully mixed, making the dispersed phase become smaller and more uniformly dispersed in the continuous phase, forming a stable emulsion or suspension, reducing the stratification and precipitation of the liquid medicine, and improving the stability and uniformity of the liquid medicine. The outer circumference of the three positioning columns 204 is provided with a flow guide cover 3. The flow guide cover 3 is funnel-shaped, the narrow end of the flow guide cover 3 covers the homogenizer 206, the bottom of the flow guide cover 3 is fixed to the bottom of the containing cylinder 102 through multiple support columns 4, the flared end of the flow guide cover 3 is arranged at the top of the containing cylinder 102, and the flow guide cover 3 corresponds to the liquid inlet 103 to allow the liquid medicine entering the containing cylinder 102 to first enter the flow guide cover 3, so that the flow guide cover 3 limits the solute in the liquid medicine, so that most of the solute in the liquid medicine is arranged close to the homogenizer 206 or the stirring fan 203, thereby improving the speed of the homogenizer 206 and the stirring fan 203 breaking the solute to some extent. When the drive motor 201 drives the drive shaft 202 to rotate, the stirring fan 203 and the homogenizer 206 rotate stably, most of the solute in the liquid medicine quickly contacts the homogenizer 206 and the stirring fan 203. When the homogenizer 206 and the stirring fan 203 continuously rotate, a negative pressure is generated at the corresponding position of the flow guide cover 3, thereby enabling the liquid medicine between the outer circumference of the flow guide cover 3 and the inside of the containing cylinder 102 to be sucked into the inside of the flow guide cover 3 from the bottom of the flow guide cover 3. After the liquid medicine is homogenized by the rotation of the homogenizer 206 and the stirring fan 203, the homogenized liquid medicine will pass through the screen holes uniformly arranged on the flow guide cover 3 to be discharged between the outer circumference of the flow guide cover 3 and the inner wall of the containing cylinder 102, so that the liquid medicine circulates into the inside of the flow guide cover 3 and is then discharged, thereby further improving the homogenization effect of the liquid medicine, and also maintaining the homogenization efficiency of the liquid medicine by cooperating with the initial restraining effect of the flow guide cover 3 on the solute in the liquid medicine.

[0026] Three positioning columns 204 are provided with turbulence strips 205, and the turbulence strips 205 are continuously arranged along the axial direction of the positioning columns 204. The plurality of turbulence strips 205 can disturb the turbulent flow generated when the homogenizer 206 and the stirring fan 203 drive the stirring rotation of the liquid medicine, thereby increasing the frequency of mutual collision and friction of the particles or droplets in the liquid medicine, and then the breaking speed of the larger particles or droplets in the liquid medicine is increased, and the homogenization effect of the liquid medicine is further improved. The rough layer 106 is arranged on the inner wall of the containing cylinder 102. The rough layer 106 can hinder and interfere with the liquid medicine flowing between the flow guide cover 3 and the inner wall of the containing cylinder 102 after passing through the screen hole, thereby destroying the laminar flow state of the liquid medicine and promoting the change of the liquid medicine to turbulent flow. The protruding part of the rough layer 106 can generate a shearing force on the liquid medicine close to the cylinder wall. The shearing force can further break the particles or droplets, reduce the size of the particles or droplets, and more uniformly distribute the particles or droplets in the liquid medicine to improve the homogenization degree of the liquid medicine.

[0027] In specific use, as shown in the figure, Figure 3 The opening and closing cover 104 is opened, and then the staff can pour the liquid medicine into the flow guide cover 3. As shown in the figure, Figure 2 The opening and closing cover 104 is closed, so that most of the solute in the liquid medicine is limited in the flow guide cover 3. Then the driving motor 201 is started to drive the stirring fan 203 and the homogenizer 206 to rotate through the driving shaft 202, finely crush the solute limited in the flow guide cover 3, and improve the efficiency of the solute uniformly distributed in the liquid medicine. At the same time, the liquid medicine between the flow guide cover 3 and the inner wall of the containing cylinder 102 enters the flow guide cover 3 and is discharged from the screen holes uniformly arranged on the flow guide cover 3 to form a circulation to further improve the homogenization efficiency and effect of the liquid medicine. During the circulation process, the turbulence strips 205 and the rough layer 106 are used to make the solute in the liquid medicine collide and press each other, thereby further improving the homogenization effect and efficiency of the liquid medicine. After a certain period of time, the opening and closing cover 104 can be opened by the clamping buckle 105 to pour out the homogenized liquid medicine for subsequent processing or packaging.

[0028] The specific embodiments of the utility model are described above. It should be understood that the utility model is not limited to the above specific embodiments, and those skilled in the art can make various modifications or changes within the scope of claims, which does not affect the essential content of the utility model.

Claims

1. A homogenizing mixing device, characterized by: It has a vertical setting containing cylinder (102), set in the containing cylinder (102) homogenizing assembly (2) and cover set in the homogenizing assembly (2) fairing (3), fairing (3) bottom through a plurality of support column (4) and containing cylinder (102) bottom wall fixed connection; The homogenizing assembly (2) includes a drive motor (201) arranged on the upper side of the containing cylinder (102), the drive motor (201) is driven by a drive shaft (202) penetrating the containing cylinder (102), the drive shaft (202) drives a stirring fan (203) and a homogenizer (206) arranged in the containing cylinder (102); The fairing (3) is a conical cylinder with sieve holes on the outer periphery, the narrow end of the fairing (3) is arranged downward, the containing cylinder (102) is provided with a liquid inlet (103) corresponding to the flared end of the fairing (3) for pouring liquid, so that the liquid poured from the liquid inlet (103) into the containing cylinder (102) first enters the inside of the fairing (3) and then diffuses to the inner wall of the containing cylinder (102) through the sieve holes.

2. A homogenizing mixing device as claimed in claim 1, characterized in that: The homogenizer (206) and the upper inner wall of the containing cylinder (102) are provided with three positioning columns (204).

3. A homogenizing mixing device as claimed in claim 2, characterized in that: The positioning column (204) is uniformly provided with a plurality of turbulence strips (205) on the outer periphery, and the turbulence strips (205) are continuously arranged along the axial direction of the positioning column (204).

4. A homogenizing mixing device as claimed in claim 1, characterized in that: A rough layer (106) for obstructing the flow of liquid is arranged on the inner wall of the containing cylinder (102).

5. A homogenizing mixing device as claimed in claim 1, characterized in that: The stirring fan (203) is arranged corresponding to the middle part of the fairing (3).

6. A homogenizing mixing device as claimed in claim 1, characterized in that: The homogenizer (206) is arranged corresponding to the narrow end of the fairing (3), so that the liquid circulates from the bottom into the fairing (3), and is discharged from the sieve holes of the fairing (3).

7. A homogenizing mixing device as claimed in claim 1, characterized in that: A opening and closing cover (104) for opening and closing the liquid inlet (103) is rotatably arranged on the containing cylinder (102), and a clamping handle (105) for clamping with the drive motor (201) is arranged on the opening and closing cover (104).

8. A homogenizing mixing device as claimed in claim 1, characterized in that: A plurality of supporting feet (101) are uniformly arranged on the bottom surface of the containing cylinder (102).