Cell culture device for tumor early screening

Abstract

The utility model relates to the technical field of cell culture devices, and discloses a cell culture device for tumor early screening, which solves the problem that the existing cell culture device is poor in use effect, and comprises a water bath incubator, a controller is arranged at one end of the top of the water bath incubator, and a temperature sensor is arranged at one end in the water bath incubator. A ceramic heating rod is arranged in the middle of the interior of the water bath incubator, the water bath incubator is filled with heating water, a culture dish supporting table is arranged at the top end of the interior of the water bath incubator, and a plurality of through holes are formed in the culture dish supporting table; an oscillation driving mechanism connected with the culture dish supporting table is arranged in the middle of one end in the water bath incubator, and the oscillation driving mechanism is composed of a servo motor, a rotary table, a first short shaft, a connecting plate and a second short shaft; according to the cell culture device, the culture dish can be subjected to water-bath constant-temperature heating, and meanwhile, the culture dish can be oscillated, so that cells and a culture solution are uniformly mixed.

Description

Technical Field

[0001] This invention belongs to the field of cell culture device technology, specifically a cell culture device for early tumor screening. Background Technology

[0002] Cell culture is required in the early screening of tumors. The commonly used cell culture method is to place culture dishes containing cells and tissues inside an incubator. However, existing incubators have the disadvantage of poor temperature control, which affects the cell culture effect. At the same time, existing incubators are not convenient for shaking the culture dishes containing cells and tissues during the culture process. Generally, the culture dishes are shaken manually before culture, which is not convenient to use. Therefore, this application improves the existing technology and proposes a cell culture device for early tumor screening. Utility Model Content

[0003] In view of the above situation and to overcome the shortcomings of the existing technology, this utility model provides a cell culture device for early tumor screening, which effectively solves the problem of poor performance of existing cell culture devices.

[0004] To achieve the above objectives, this utility model provides the following technical solution: a cell culture device for early tumor screening, comprising a water bath incubator, a controller fixedly mounted at one end of the top of the water bath incubator, a cover plate mounted at the other end of the top of the water bath incubator, a temperature sensor fixedly mounted at one end of the interior of the water bath incubator, a ceramic heating rod fixedly mounted in the middle of the interior of the water bath incubator, heated water filling the interior of the water bath incubator, a culture dish support platform mounted at the top of the interior of the water bath incubator, and several through holes formed on the culture dish support platform. A vibration drive mechanism connected to the petri dish support is fixedly installed at the middle position of one end of the unit. The temperature sensor, ceramic heating rod and vibration drive mechanism are all electrically connected to the controller. The vibration drive mechanism consists of a servo motor, a turntable, a first short shaft, a connecting plate and a second short shaft. The servo motor is fixedly connected to one end inside the water bath incubator. The turntable is fixedly connected to the output shaft of the servo motor. The first short shaft is fixedly connected to the side of the top of the turntable. The second short shaft is fixedly connected to the middle position of one end of the top of the petri dish support. The connecting plate is connected between the first short shaft and the second short shaft and is rotatably connected to them.

[0005] Preferably, the connecting plate is rotatably connected to both short shaft one and short shaft two via bearings.

[0006] Preferably, the cover plate is rotatably connected to the water bath incubator via a hinge, the cover plate is provided with a handle and a locking plate, and a sealing ring matching the water bath incubator is fixedly provided on the side of the bottom end of the cover plate.

[0007] Preferably, the petri dish support platform consists of a platform and a flexible rubber frame, with the flexible rubber frame connected between the platform and the inner wall of the water bath incubator.

[0008] Preferably, a rubber gasket is fixedly provided on the inner sidewall of the through hole.

[0009] Preferably, a number of L-shaped limiting arms are fixedly provided on the side of the top of the platform, and a number of limiting grooves matching the L-shaped limiting arms are opened on the inner side wall of the water bath incubator.

[0010] Compared with the prior art, the beneficial effects of this utility model are:

[0011] (1) In operation, by setting up a water bath incubator, temperature sensor and ceramic heating rod, it is possible to carry out constant temperature heating of multiple culture dishes in a water bath, improve the uniformity of heating, ensure that each culture dish is heated evenly, and improve the effect of cell culture.

[0012] (2) By setting up an oscillation drive mechanism consisting of a servo motor, a turntable, a short shaft one, a connecting plate and a short shaft two, the culture dish support platform can be driven to oscillate, thereby driving the culture dish to oscillate, so that the cells inside the culture dish are mixed evenly with the culture medium, improving the culture efficiency. By setting up a culture dish support platform consisting of a platform and a flexible rubber frame, the mobility can be improved, and water inside the water bath incubator can be prevented from splashing out. By setting up rubber gaskets, the culture dish can be buffered and protected to avoid damage to the culture dish. The platform can be limited by the L-shaped limiting arm and the limiting slide groove to improve its stability. Attached Figure Description

[0013] The accompanying drawings are provided to further understand the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation thereof.

[0014] In the attached diagram:

[0015] Figure 1 This is a schematic diagram of the cell culture device for early tumor screening according to the present invention.

[0016] Figure 2 This is a partial structural diagram of the cell culture device for early tumor screening according to the present invention.

[0017] Figure 3 This is a schematic diagram of the connection structure between the oscillation drive mechanism and the petri dish support platform of this utility model;

[0018] Figure 4 This is a schematic diagram of the oscillation drive mechanism of this utility model;

[0019] In the diagram: 1. Water bath incubator; 2. Controller; 3. Cover plate; 4. Temperature sensor; 5. Ceramic heating rod; 6. Petri dish support platform; 7. Through hole; 8. Oscillation drive mechanism; 9. Servo motor; 10. Turntable; 11. Short shaft one; 12. Connecting plate; 13. Short shaft two; 14. Bearing; 15. Hinge; 16. Handle; 17. Locking plate; 18. Sealing ring; 19. Platform; 20. Flexible rubber frame; 21. Rubber gasket; 22. L-shaped limiting arm; 23. Limiting groove. Detailed Implementation

[0020] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0021] Depend on Figures 1 to 4 This invention discloses a cell culture device for early tumor screening, comprising a water bath incubator 1, a controller 2 fixedly mounted at one end of the top of the water bath incubator 1, a cover plate 3 mounted at the other end of the top of the water bath incubator 1, a temperature sensor 4 fixedly mounted at one end of the interior of the water bath incubator 1, a ceramic heating rod 5 fixedly mounted at the middle position inside the water bath incubator 1, the interior of the water bath incubator 1 being filled with heated water, a culture dish support platform 6 mounted at the top of the interior of the water bath incubator 1, the culture dish support platform 6 having several through holes 7, and a vibration drive mechanism 8 fixedly mounted at the middle position of one end of the interior of the water bath incubator 1, connected to the culture dish support platform 6. The temperature sensor 4, ceramic heating rod 5, and oscillation drive mechanism 8 are all electrically connected to the controller 2. The oscillation drive mechanism 8 consists of a servo motor 9, a turntable 10, a first short shaft 11, a connecting plate 12, and a second short shaft 13. The servo motor 9 is fixedly connected to one end inside the water bath incubator 1. The turntable 10 is fixedly connected to the output shaft of the servo motor 9. The first short shaft 11 is fixedly connected to the side of the top of the turntable 10. The second short shaft 13 is fixedly connected to the middle position of one end of the top of the petri dish support platform 6. The connecting plate 12 is connected between the first short shaft 11 and the second short shaft 13 and is rotatably connected to them. The connecting plate 12 is rotatably connected to the first short shaft 11 and the second short shaft 13 through bearings 14.

[0022] In use, the cell culture dish is inserted into the through hole 7 on the culture dish support 6. The water is heated by the ceramic heating rod 5. The heated water is used to heat multiple culture dishes in a water bath to improve the uniformity of heating. The temperature sensor 4 can monitor the water temperature. The servo motor 9 drives the turntable 10 to rotate. The turntable 10 drives the short shaft 11 to make a circular motion. The short shaft 11 drives the connecting plate 12 and the short shaft 2 13 to move, thereby driving the culture dish support 6 to vibrate, so that the cells and culture medium are mixed evenly and the cell culture efficiency is improved.

[0023] Depend on Figures 1 to 3 As shown, the cover plate 3 is rotatably connected to the water bath incubator 1 via a hinge 15. The cover plate 3 is provided with a handle 16 and a locking plate 17. A sealing ring 18 matching the water bath incubator 1 is fixedly provided on the side of the bottom end of the cover plate 3. The culture dish support platform 6 is composed of a platform 19 and a flexible rubber frame 20. The flexible rubber frame 20 is connected between the platform 19 and the inner side wall of the water bath incubator 1. A rubber gasket 21 is fixedly provided on the inner side wall of the through hole 7. Several L-shaped limiting arms 22 are fixedly provided on the side of the top end of the platform 19. Several limiting grooves 23 matching the L-shaped limiting arms 22 are opened on the inner side wall of the water bath incubator 1.

[0024] The flexible rubber frame 20 can prevent water from splashing out of the water bath incubator 1, the rubber gasket 21 can buffer the culture dish and prevent it from being damaged, and the L-shaped limiting arm 22 and the limiting slide 23 can achieve lateral limiting of the platform 19 and improve its stability.

[0025] In operation, the system is equipped with a water bath incubator, temperature sensor, and ceramic heating rod, enabling constant temperature heating of multiple culture dishes in a water bath. This improves heating uniformity, ensuring even heating of each dish and enhancing cell culture efficiency. A vibration drive mechanism, consisting of a servo motor, turntable, short shaft one, connecting plate, and short shaft two, drives the culture dish support platform to vibrate, thus oscillating the culture dishes and ensuring uniform mixing of cells and culture medium, improving culture efficiency. The culture dish support platform, composed of a platform and flexible rubber frame, enhances mobility and prevents water from splashing out of the water bath incubator. Rubber gaskets provide cushioning protection for the culture dishes, preventing damage. L-shaped limiting arms and limiting grooves limit the platform's position, improving its stability.

Claims

1. A cell culture device for early tumor screening, comprising a water bath incubator (1), characterized in that: A controller (2) is fixedly installed at one end of the top of the water bath incubator (1), and a cover plate (3) is installed at the other end of the top of the water bath incubator (1). A temperature sensor (4) is fixedly installed at one end of the interior of the water bath incubator (1). A ceramic heating rod (5) is fixedly installed in the middle of the interior of the water bath incubator (1). The interior of the water bath incubator (1) is filled with heated water. A petri dish support platform (6) is installed at the top of the interior of the water bath incubator (1). Several through holes (7) are opened on the petri dish support platform (6). An oscillation drive mechanism (8) connected to the petri dish support platform (6) is fixedly installed in the middle of one end of the interior of the water bath incubator (1). The temperature sensor ( 4) The ceramic heating rod (5) and the oscillation drive mechanism (8) are both electrically connected to the controller (2). The oscillation drive mechanism (8) consists of a servo motor (9), a turntable (10), a short shaft one (11), a connecting plate (12), and a short shaft two (13). The servo motor (9) is fixedly connected to one end inside the water bath incubator (1). The turntable (10) is fixedly connected to the output shaft of the servo motor (9). The short shaft one (11) is fixedly connected to the side of the top of the turntable (10). The short shaft two (13) is fixedly connected to the middle position of the top end of the petri dish support platform (6). The connecting plate (12) is connected between the short shaft one (11) and the short shaft two (13) and rotates with them.

2. The cell culture device for early tumor screening according to claim 1, characterized in that: The connecting plate (12) is rotatably connected to the first short shaft (11) and the second short shaft (13) via bearings (14).

3. The cell culture device for early tumor screening according to claim 1, characterized in that: The cover plate (3) is rotatably connected to the water bath incubator (1) via a hinge (15). The cover plate (3) is provided with a handle (16) and a locking plate (17). A sealing ring (18) matching the water bath incubator (1) is fixedly provided on the side of the bottom end of the cover plate (3).

4. The cell culture device for early tumor screening according to claim 1, characterized in that: The culture dish support platform (6) consists of a platform (19) and a flexible rubber frame (20), with the flexible rubber frame (20) connected between the platform (19) and the inner wall of the water bath incubator (1).

5. A cell culture device for early tumor screening according to claim 1, characterized in that: A rubber gasket (21) is fixedly provided on the inner side wall of the through hole (7).

6. A cell culture device for early tumor screening according to claim 4, characterized in that: The top side of the platform (19) is fixedly provided with several L-shaped limiting arms (22), and the inner side wall of the water bath incubator (1) is provided with several limiting grooves (23) that match the L-shaped limiting arms (22).

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