Cleaning and separating device, cleaning and separating equipment and sample testing analyzer

Abstract

The utility model relates to the technical field of automatic equipment for in vitro diagnosis, and discloses a cleaning and separating device, cleaning and separating equipment and a sample testing analyzer, the cleaning and separating device comprises a base and a mounting plate, a driving piece is arranged on the base, a driving shaft of the driving piece deviates from the base and is connected with the mounting plate, and the mounting plate is connected with the base. The driving device is used for driving the mounting plate to move up and down relative to the base, a plurality of mixers are arranged on the mounting plate at intervals, and the mixers are suitable for independently mixing the reaction containers. According to the cleaning and separating device, the driving part is adopted to control the mounting plate to move up and down so as to drive the plurality of mixers to move up and down synchronously, so that the mixers are close to or far away from the reaction container and mix the reaction container, the driving structure of the mixers is simplified, the control difficulty of the mixers is reduced, and the production efficiency is improved. Therefore, the working efficiency of cleaning and separating is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to in vitro diagnosis automation equipment technical field, concretely relates to cleaning separation device, cleaning separation equipment and sample test analysis appearance. BACKGROUND

[0002] In order to ensure the accuracy of chemiluminescence immunoassay, it is necessary to use a cleaning separation device to clean the magnetic beads in the reaction container to remove substances that are not combined with solid-phase antigen and antibody and interference substances such as serum that are non-specifically adsorbed on the solid-phase carrier during the reaction.

[0003] At present, the cleaning separation device generally consists of a magnetic adsorption mechanism, a rotating mechanism, a lifting driving mechanism, a cleaning mechanism and a mixing mechanism. The reaction container is placed on the rotating mechanism, and the rotating mechanism drives the reaction container to rotate to move the reaction container to a cleaning liquid inlet level, a cleaning liquid outlet level and a cleaning liquid mixing level. The magnetic adsorption mechanism adsorbs the magnetic beads, so that the magnetic beads are attached to the inside of the bottom of the reaction container. When the reaction container moves to the cleaning liquid inlet level and the cleaning liquid outlet level, the cleaning mechanism performs liquid inlet and liquid outlet actions. When the reaction container moves to the cleaning liquid mixing level, the mixing mechanism performs a mixing action.

[0004] Among them, the mixing mechanism generally has multiple mixers to achieve multiple mixing of the reaction container. However, each mixer needs an independent driving mechanism, which makes the control of the mixing mechanism difficult and the manufacturing cost high. SUMMARY

[0005] Therefore, the utility model provides a cleaning separation device, a cleaning separation equipment and a sample test analysis appearance to solve the problem that each mixer of the mixing mechanism needs an independent driving mechanism, which makes the control difficult and the manufacturing cost high.

[0006] In the first aspect, the utility model provides a cleaning separation device, which comprises a base and a mounting plate, a driving member is arranged on the base, the driving shaft of the driving member is away from the base and is connected with the mounting plate, which is used to drive the mounting plate to move up and down relative to the base, multiple mixers are arranged on the mounting plate at intervals, and each mixer is suitable for independently mixing a reaction container.

[0007] Advantages: the cleaning separation device of the utility model uses a driving member to control the mounting plate to move up and down, to simultaneously drive multiple mixers to move up and down synchronously, so that the mixers are close to or away from the reaction container and mix the reaction container, which simplifies the driving structure of the mixers and reduces the control difficulty of the mixers, thereby improving the working efficiency of the cleaning separation.

[0008] In an alternative embodiment, at least one guide rail assembly is further arranged between the base and the mounting plate, and the at least one guide rail assembly slides in the up-down direction.

[0009] Beneficial effects: By arranging at least one guide rail assembly between the base and the mounting plate, the shaking of the mounting plate can be reduced, the stability of the up-down movement of the mounting plate can be ensured, and the synchronous rising and falling of multiple mixers can be ensured.

[0010] In an alternative embodiment, the guide rail assembly comprises:

[0011] A support plate is fixedly arranged on the top of the base and is spaced apart from the driving member, and a sliding rail extending in the up-down direction is arranged on one side surface of the support plate.

[0012] A sliding plate is fixedly connected to the mounting plate at the upper end, and a sliding block matched with the sliding rail is arranged at the lower end of the sliding plate.

[0013] Beneficial effects: The support plate is used to support the sliding plate and the mounting plate, and the sliding plate slides up and down relative to the mounting plate, which is simple in structure and convenient for manufacturing and use.

[0014] In an alternative embodiment, a bottom plate is arranged on the top of the base, the bottom plate is spaced apart from the mounting plate, and the support plate and the driving member are both fixedly arranged on the top surface of the bottom plate.

[0015] Beneficial effects: By fixing the support plate and the driving member on the top surface of the bottom plate, the flatness of the support plate and the driving member can be ensured, and the multiple mixers can be further ensured to be located on the same horizontal plane.

[0016] In a second aspect, the utility model also provides a cleaning and separating device, which comprises:

[0017] The cleaning and separating device, the top of the base is further provided with a support shaft;

[0018] A magnetic suction disc is sleeved on the support shaft, and a magnetic member is arranged around the magnetic suction disc, and the magnetic member is suitable for adsorbing magnetic beads in a reaction container.

[0019] A rotating mechanism comprises a rotating driving member and a rotating disc, the rotating disc is movably sleeved on the support shaft, a plurality of support portions are arranged on the circumferential side of the end surface of the rotating disc and are spaced apart, each support portion is suitable for bearing a reaction container, the rotating driving member is connected with the rotating disc and is used for driving the rotating disc to rotate to a specified position.

[0020] A cleaning mechanism is arranged on the support shaft and is located at the upper end of the rotating disc, and is used for liquid suction and injection of the reaction container.

[0021] Beneficial effects: Because the cleaning and separating device comprises the cleaning and separating device described above, it has the same effects as the cleaning and separating device, that is, the driving member is used to control the up-down movement of the mounting plate to simultaneously drive the multiple mixers to move up and down synchronously, so that the mixers are close to or away from the reaction container and the reaction container is mixed, the driving structure of the mixer is simplified, and the control difficulty of the mixer is reduced, thereby facilitating the improvement of the working efficiency of the cleaning and separating.

[0022] In an alternative embodiment, the cleaning mechanism comprises:

[0023] A liquid injection disc is sleeved on the support shaft and located at the upper end of the rotating disc, and a plurality of liquid injection portions are arranged on the circumferential side of the liquid injection disc corresponding to the support portions;

[0024] A lifting driving member is arranged at the top of the liquid injection disc, and the lifting driving member is connected with the plurality of liquid suction portions and used to drive the plurality of liquid suction portions to lift, and the plurality of liquid suction portions correspond to the support portions and are adapted to enter and exit the reaction container through the liquid injection disc.

[0025] Beneficial effects: The plurality of liquid injection portions are used to inject cleaning liquid into the reaction container, and the lifting driving member is used to drive the plurality of liquid suction portions to lift, thereby realizing the liquid suction action.

[0026] In an alternative embodiment, the cleaning and separating device sequentially comprises three-stage liquid injection positions, three-stage magnetic attraction positions and three-stage liquid suction positions, each of the magnetic attraction positions is composed of a plurality of magnetic members, and each of the liquid suction positions is arranged above the last magnetic member of each of the magnetic attraction positions.

[0027] Beneficial effects: The three-stage liquid injection positions, the three-stage magnetic attraction positions and the three-stage liquid suction positions are arranged, so that the magnetic beads in the reaction container can be cleaned and separated three times, and the cleaning and separating process is more thorough. The three-stage liquid suction positions are arranged above the last magnetic member of each of the magnetic attraction positions, so that the occupied space of the three-stage liquid suction positions is saved, and the waste liquid can be quickly sucked out after the magnetic attraction is completed.

[0028] In an alternative embodiment, the cleaning and separating device sequentially comprises an entering and exiting position, a first-stage liquid injection position, a first-stage magnetic attraction position, a first-stage liquid suction position, a second-stage liquid injection position, a second-stage magnetic attraction position, a second-stage liquid suction position, a third-stage liquid injection position, a third-stage magnetic attraction position, a third-stage liquid suction position and a substrate liquid injection position.

[0029] Beneficial effects: The cleaning and separating device sequentially comprises the entering and exiting position, the first-stage liquid injection position, the first-stage magnetic attraction position, the first-stage liquid suction position, the second-stage liquid injection position, the second-stage magnetic attraction position, the second-stage liquid suction position, the third-stage liquid injection position, the third-stage magnetic attraction position, the third-stage liquid suction position and the substrate liquid injection position, so that the three-stage cleaning and separating can be realized by one rotation of the rotating disc, and the structure is simple and the volume is small.

[0030] In an alternative embodiment, the substrate liquid injection position comprises a first substrate liquid injection position and a second substrate liquid injection position.

[0031] Beneficial effects: By setting the first substrate injection liquid level and the second substrate injection liquid level, different systems can be injected with substrates according to different systems, compatible with the cleaning and separation of reaction containers of various systems, and the application range is improved.

[0032] In a third aspect, the utility model also provides a sample test analyzer, including the cleaning and separation equipment.

[0033] Beneficial effects: Because the sample test analyzer includes the cleaning and separation equipment, has the same effect as the cleaning and separation equipment, which will not be repeated here. BRIEF DESCRIPTION OF DRAWINGS

[0034] In order to more clearly illustrate the specific embodiment of the utility model or the technical scheme in the prior art, the drawings needed in the specific embodiment or the prior art description will be briefly introduced below, and obviously, the drawings in the following description are some embodiments of the utility model, and those skilled in the art can also obtain other drawings according to these drawings without creative labor.

[0035] Figure 1 It is a structure schematic view of a cleaning and separation equipment of the utility model embodiment;

[0036] Figure 2 It is a structure schematic view of a cleaning and separation device of the utility model embodiment;

[0037] Figure 3 It is a first local structure schematic view of a cleaning and separation equipment of the utility model embodiment;

[0038] Figure 4 It is a second local structure schematic view of a cleaning and separation equipment of the utility model embodiment;

[0039] Figure 5 It is a third local structure schematic view of a cleaning and separation equipment of the utility model embodiment;

[0040] Figure 6 It is a local overhead schematic view of a cleaning and separation equipment of the utility model embodiment.

[0041] BRIEF DESCRIPTION OF DRAWINGS

[0042] 1, base; 2, mounting plate; 3, drive; 301, drive shaft; 4, mixing device; 5, guide rail assembly; 501, support plate; 502, sliding plate; 6, bottom plate; 7, flatness clamp; 8, mounting clamp; 9, support shaft; 10, magnetic suction disc; 11, rotating mechanism; 1101, rotating drive; 1102, rotating disc; 12, cleaning mechanism; 1201, liquid injection disc; 1202, liquid injection part; 12021, first substrate liquid injection part; 12022, second substrate liquid injection part; 1203, lifting drive; 1204, liquid suction part; 13, reaction vessel;

[0043] 101, access position; 102, first-stage liquid injection position; 103, first-stage magnetic suction position; 104, first-stage liquid suction position; 105, second-stage liquid injection position; 106, second-stage magnetic suction position; 107, second-stage liquid suction position; 108, third-stage liquid injection position; 109, third-stage magnetic suction position; 110, third-stage liquid suction position; 111, first substrate liquid injection position; 112, second substrate liquid injection position. DETAILED DESCRIPTION

[0044] To make the purpose, technical scheme and advantages of the embodiments of the present application clearer, the technical scheme in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0045] The embodiments of the present application will be described below with reference to Figures 1 to 6 .

[0046] According to the embodiments of the present application, on the one hand, as shown in Figure 1 and Figure 2 , a cleaning and separating device is provided, comprising a base 1 and a mounting plate 2, the top of the base 1 is provided with a drive 3, the drive shaft 301 of the drive 3 is away from the base 1 and is connected with the mounting plate 2, for driving the mounting plate 2 to move up and down relative to the base 1, a plurality of mixing devices 4 are arranged on the mounting plate 2 at intervals, and each mixing device 4 is adapted to independently mix a reaction vessel 13.

[0047] It can be seen that the cleaning and separating device provided by the embodiments of the present application adopts the drive 3 to control the mounting plate 2 to move up and down, so as to simultaneously drive the plurality of mixing devices 4 to move up and down synchronously, so that the mixing device 4 is close to or away from the reaction vessel 13, and the reaction vessel 13 is mixed, which simplifies the driving structure of the mixing device 4 and reduces the control difficulty of the mixing device 4, thereby being conducive to improving the working efficiency of cleaning and separating.

[0048] Compared with the traditional mode that one driving member 3 is arranged corresponding to each mixing device 4 to control the up-down movement of the mixing device 4, the embodiment of the utility model reduces the number of the driving member 3, controls the up-down movement of the mixing device 4 more simply, and simplifies the structure.

[0049] It should be noted that the structure of the driving member 3 is not limited in the embodiment of the utility model, and any existing structure can be selected according to the need, as long as the driving member 3 can drive the mounting plate 2 to move up and down relative to the base 1. For example, the driving member 3 is a telescopic motor, and the driving shaft 301 of the driving member 3 drives the mounting plate 2 to move up and down relative to the base 1 through the telescopic belt. Alternatively, the driving member 3 is a lead screw motor, the driving shaft 301 of the driving member 3 is a lead screw, the lead screw is threadedly connected with the mounting plate 2, and the lead screw motor is rotated to drive the mounting plate 2 to move up and down relative to the base 1.

[0050] In one embodiment, as shown in Figure 2 The base 1 and the mounting plate 2 are further provided with at least one guide rail assembly 5, and the at least one guide rail assembly 5 slides in the up-down direction. By arranging the at least one guide rail assembly 5 between the base 1 and the mounting plate 2, the shaking of the mounting plate 2 can be reduced, the stability of the up-down movement of the mounting plate 2 can be ensured, and the synchronous rising and falling of the plurality of mixing devices 4 can be ensured.

[0051] It should be noted that the structure of the guide rail assembly 5 is not limited in the embodiment of the utility model, and any existing structure can be selected according to the need. In addition, the number of the guide rail assembly 5 is not limited, and one, two or more than two can be selected.

[0052] Further, in one embodiment, as shown in Figure 2 The guide rail assembly 5 mainly comprises a support plate 501 and a sliding plate 502. The support plate 501 is fixedly arranged on the top of the base 1 and is arranged in a spaced manner with the driving member 3, and a sliding rail extending in the up-down direction is arranged on one side surface. The upper end of the sliding plate 502 is fixedly connected with the mounting plate 2, and the lower end is provided with a sliding block matched with the sliding rail. The support plate 501 is used for supporting the sliding plate 502 and the mounting plate 2, and the sliding plate 502 slides up and down relative to the mounting plate 2, which is simple in structure and convenient to manufacture and use.

[0053] Further, in one embodiment, as shown in Figure 2 A pair of guide rail assemblies 5 are arranged, and the pair of guide rail assemblies 5 are respectively arranged in a spaced manner on the two sides of the driving member 3 and form a triangle shape with the driving member 3. By arranging the pair of guide rail assemblies 5 and arranging the pair of guide rail assemblies 5 in a spaced manner on the two sides of the driving member 3 to form a triangle shape with the driving member 3, the movement stability of the mounting plate 2 can be further improved.

[0054] In one embodiment, the top of the mounting plate 2 is also provided with a flatness clamp 7, which is used to adjust the position of the mounting plate 2 so that the plurality of mixers 4 are located on the same horizontal plane. By adjusting the position of the mounting plate 2 through the flatness clamp 7, it can be ensured that the plurality of mixers 4 are located on the same horizontal plane and are synchronized to rise and fall, so as to improve the uniformity of multiple mixing. Compared with staggered arrangement, the plurality of mixers 4 located on the same horizontal plane can better utilize the space, facilitate overall layout design and have stronger anti-interference performance.

[0055] In one embodiment, as shown in Figure 2 the top of the base 1 is provided with a bottom plate 6, the bottom plate 6 is arranged in a spaced manner with the mounting plate 2, and the support plate 501 and the driving member 3 are fixedly arranged on the top surface of the bottom plate 6. By fixing the support plate 501 and the driving member 3 on the top surface of the bottom plate 6, the flatness of the support plate 501 and the driving member 3 can be ensured, and the plurality of mixers 4 located on the same horizontal plane can be further ensured.

[0056] Further, the base 1, the bottom plate 6 and the mounting plate 2 are all machined parts, which have high machining precision and stability, and can effectively ensure the flatness and dimensional accuracy of the surfaces of the bottom plate 6 and the mounting plate 2.

[0057] It should be noted that the fixed connection mode of the support plate 501, the driving member 3 and the bottom plate 6 is not limited in the embodiments of the present application, and a detachable fixing mode such as screw connection can be adopted according to the needs, so as to facilitate installation and maintenance, or a fastening type connection mode such as welding connection can be adopted, which has strong structural stability.

[0058] In one embodiment, as shown in Figure 2 the top of the mounting plate 2 is provided with a plurality of mixers 4 in a spaced manner. The mixer 4 is fixed on the top of the mounting plate 2, and the mixing is stable, which is beneficial to the mixer 4 to approach or move away from the reaction container 13 and mix the reaction container 13. The mixer 4 can be adjusted in levelness through the mounting clamp 8, so that the plurality of mixers 4 are located on the same horizontal plane, and the mounting clamp 8 is removed after adjustment.

[0059] According to the embodiments of the present application, on the other hand, as shown in Figure 1 a cleaning and separating device is also provided, mainly comprising: a cleaning and separating device, a magnetic suction disc 10, a rotating mechanism 11 and a cleaning mechanism 12.

[0060] Further, the top of the base 1 is further provided with a support shaft 9. The magnetic suction disc 10 is sleeved on the support shaft 9, and a magnetic member is arranged around the magnetic suction disc 10, and the magnetic member is suitable for adsorbing magnetic beads in the reaction container 13. The rotating mechanism 11 mainly comprises a rotating driving member 1101 and a rotating disc 1102. The rotating disc 1102 is movably sleeved on the support shaft 9, and a plurality of support portions are arranged on the end face of the rotating disc 1102 in a spaced manner, and each support portion is suitable for carrying the reaction container 13. The rotating driving member 1101 is connected with the rotating disc 1102, and is used for driving the rotating disc 1102 to rotate to a specified position. The cleaning mechanism 12 is arranged on the support shaft 9 and located at the upper end of the rotating disc 1102, and is used for sucking and injecting liquid into the reaction container 13.

[0061] Because the cleaning and separating device comprises the cleaning and separating device, has the same effect as the cleaning and separating device, that is, the driving member 3 is used for controlling the mounting plate 2 to move up and down, so as to drive the plurality of mixers 4 to move up and down synchronously, so that the mixer 4 is close to or away from the reaction container 13, and the mixer 4 is mixed with the reaction container 13. The driving structure of the mixer 4 is simplified, and the control difficulty of the mixer 4 is reduced, so as to improve the working efficiency of the cleaning and separating.

[0062] Specifically, a plurality of through holes are arranged on the circumferential side of the rotating disc 1102 in a spaced manner, and the through holes are used as the support portions and carry the reaction container 13. The support shaft 9 is installed on the bottom plate 6, the magnetic suction disc 10 is fixedly sleeved on the support shaft 9, and the rotating disc 1102 can periodically rotate relative to the magnetic suction disc 10 and the cleaning mechanism 12. The rotating driving member 1101 drives the rotating disc 1102 to rotate, and the reaction container 13 is transported to a specified position. For example, the reaction container 13 is transported to a position corresponding to the magnetic member, and the magnetic beads in the reaction container 13 are adsorbed by the magnetic member, so that the magnetic beads are attached to the bottom of the reaction container 13. The magnetic member can be a plurality of permanent magnets embedded around the magnetic suction disc 10, or a magnetic ring sleeved on the outer circumference of the magnetic suction disc 10.

[0063] In one embodiment, as shown in Figures 3 to 5 The cleaning mechanism 12 mainly comprises an injection disc 1201, a lifting driving member 1203 and a plurality of liquid suction portions 1204. The injection disc 1201 is sleeved on the support shaft 9 and located at the upper end of the rotating disc 1102. The injection disc 1201 is provided with a plurality of injection portions 1202 corresponding to the support portions along the circumferential side. The lifting driving member 1203 is arranged on the top of the injection disc 1201, and the lifting driving member 1203 is connected with the plurality of liquid suction portions 1204 and is used for driving the plurality of liquid suction portions 1204 to lift. The plurality of liquid suction portions 1204 correspond to the support portions and are suitable for entering and exiting the reaction container 13 through the injection disc 1201. The reaction container 13 is injected with cleaning liquid through the plurality of injection portions 1202, and the plurality of liquid suction portions 1204 are lifted by the lifting driving member 1203 to realize the liquid suction action.

[0064] Specifically, the liquid injection part 1202 includes a liquid injection needle and a syringe connected thereto, for realizing the liquid injection action. The liquid suction part 1204 includes a liquid suction needle and a liquid suction pump connected thereto, the liquid suction pump powering the liquid suction needle, for realizing the liquid suction action. The lifting driving member 1203 can realize the lifting action by adopting a lead screw motor. For example, the bottom of the lead screw motor is connected with the liquid injection disc 1201, and the top is connected with a liquid suction disc, and the liquid suction disc is further provided with a guide rail between the liquid injection disc 1201. The liquid suction part 1204 is fixedly arranged on the liquid suction disc. After the lead screw motor rotates, the liquid suction disc moves up and down, thereby driving the liquid suction part 1204 to move up and down.

[0065] Further, in an embodiment, the cleaning and separating device sequentially and respectively provides three-stage liquid injection positions, three-stage magnetic attraction positions, and three-stage liquid suction positions. Each stage of the magnetic attraction position is composed of a plurality of magnetic members, and each stage of the liquid suction position is arranged above the last magnetic member of each stage of the magnetic attraction position. The provision of three-stage liquid injection positions, three-stage magnetic attraction positions, and three-stage liquid suction positions can perform three cleaning and separating processes on the magnetic beads in the reaction container 13, and the cleaning and separating process is more thorough. Arranging each stage of the liquid suction position above the last magnetic member of each stage of the magnetic attraction position can save the occupied space of three liquid suction positions, and facilitate rapid suction of waste liquid after magnetic attraction is completed.

[0066] It should be noted that the number of the liquid suction part 1204 and the liquid injection part 1202 is not limited in the embodiments of the present application, and two, three or more than three can be selected according to needs.

[0067] In an embodiment, as shown in Figure 6 the cleaning and separating device has three-stage separating and cleaning positions, and sequentially provides an in-out position 101, a first-stage liquid injection position 102, a first-stage magnetic attraction position 103, a first-stage liquid suction position 104, a second-stage liquid injection position 105, a second-stage magnetic attraction position 106, a second-stage liquid suction position 107, a third-stage liquid injection position 108, a third-stage magnetic attraction position 109, a third-stage liquid suction position 110, and a substrate liquid injection position along the circumferential direction. The cleaning and separating device sequentially provides each operation position along the circumferential direction, and one rotation of the rotating disc 1102 can realize three cleaning and separating processes, and the structure is simple and the volume is small.

[0068] Further, in an embodiment, the substrate liquid injection position includes a first substrate liquid injection position 111 and a second substrate liquid injection position 112. By providing the first substrate liquid injection position 111 and the second substrate liquid injection position 112, different systems can be injected with substrates, and the cleaning and separating of reaction containers 13 of multiple systems can be compatible, thereby improving the application range.

[0069] Specifically, the plurality of liquid injection parts 1202 respectively constitute the first-stage liquid injection position 102, the second-stage liquid injection position 105, the third-stage liquid injection position 108, the first substrate liquid injection position 111, and the second substrate liquid injection position 112. As shown in Figure 5As shown, the plurality of liquid injection portions 1202 includes a first substrate liquid injection portion 12021 and a second substrate liquid injection portion 12022. The first substrate liquid injection portion 12021 serves as the first substrate liquid injection position 111, and the second substrate liquid injection portion 12022 serves as the second substrate liquid injection position 112.

[0070] Further, in one embodiment, the liquid suction position is arranged on the magnetic suction position. Arranging the liquid suction position on the magnetic suction position can save the occupied space of the liquid suction position, and facilitate quick suction of waste liquid after the magnetic operation is completed.

[0071] Specifically, the first-stage liquid suction position 104 is arranged on the first-stage magnetic suction position 103, the second-stage liquid suction position 107 is arranged on the second-stage magnetic suction position 106, and the third-stage liquid suction position 110 is arranged on the third-stage magnetic suction position 109.

[0072] The working principle of the embodiment of the utility model is as follows:

[0073] In the in-out position 101, the reaction container 13 is installed, and then the rotating disc 1102 drives the reaction container 13 to periodically rotate. The reaction container 13 first reaches below the first-stage liquid injection position 102, the cleaning liquid injection position injects cleaning liquid into the reaction container 13, and then the rotating disc 1102 drives the reaction container 13 to reach the first-stage magnetic suction position 103. The magnetic beads are adsorbed to the inner wall of the reaction container 13 under the action of the magnetic field. Then, the rotating disc 1102 drives the reaction container 13 to reach below the liquid suction portion 1204, i.e. the first-stage liquid suction position 104. The lifting driving member 1203 drives the plurality of liquid suction portions 1204 to descend and suck the waste liquid in the reaction container 13, and then rises to separate from the reaction container 13.

[0074] The reaction container 13 continues to enter below the second-stage liquid injection position 105, the cleaning liquid injection position injects cleaning liquid into the reaction container 13, and then the rotating disc 1102 drives the reaction container 13 to reach the second-stage magnetic suction position 106. The magnetic beads are adsorbed to the inner wall of the reaction container 13 under the action of the magnetic field. Then, the rotating disc 1102 drives the reaction container 13 to reach below the liquid suction portion 1204, i.e. the second-stage liquid suction position 107. The lifting driving member 1203 drives the plurality of liquid suction portions 1204 to descend and suck the waste liquid in the reaction container 13, and then rises to separate from the reaction container 13.

[0075] The reaction container 13 continues to enter below the third-stage liquid injection position 108, the cleaning liquid injection position injects cleaning liquid into the reaction container 13, and then the rotating disc 1102 drives the reaction container 13 to reach the third-stage magnetic suction position 109. The magnetic beads are adsorbed to the inner wall of the reaction container 13 under the action of the magnetic field. Then, the rotating disc 1102 drives the reaction container 13 to reach below the liquid suction portion 1204, i.e. the third-stage liquid suction position 110. The lifting driving member 1203 drives the plurality of liquid suction portions 1204 to descend and suck the waste liquid in the reaction container 13, and then rises to separate from the reaction container 13.

[0076] Finally, the reaction container 13 enters the first substrate injection position 111 and the second substrate injection position 112 in turn, and the reaction substrate is injected according to the reaction system. For example, the AP (phosphatase) system and the AE (acridinium ester) system inject the substrate or the excitation solution into the first substrate injection part 12021, and the second substrate injection part 12022 does not act. The HRP (horseradish peroxidase) system respectively injects different substrates into the first substrate injection part 12021 and the second substrate injection part 12022. The substrates of different systems need to be selected and set according to the actual situation, and the embodiments of the present application do not make too many limitations.

[0077] According to the embodiments of the present application, on the other hand, a sample test analyzer is also provided, which comprises the cleaning and separating device.

[0078] Because the sample test analyzer comprises the cleaning and separating device, it has the same effect as the cleaning and separating device, which will not be repeated here.

[0079] Although the embodiments of the present application are described in combination with the drawings, various modifications and variations can be made by those skilled in the art without departing from the spirit and scope of the present application, and such modifications and variations all fall within the scope defined by the appended claims.

Claims

1. A cleaning separation device, characterized in that The utility model provides a kind of cleaning and separating device, including: Base (1) and mounting plate (2), driving element (3) is provided on the base (1), the driving shaft (301) of the driving element (3) is away from the base (1) and is connected with the mounting plate (2), for driving the mounting plate (2) moves up and down relative to the base (1), the mounting plate (2) is spaced apart and provided with a plurality of mixers (4), each mixer (4) is adapted to mix reaction vessel (13) independently.

2. The cleaning separation apparatus of claim 1, wherein At least one guide rail assembly (5) is further provided between the base (1) and the mounting plate (2), and the at least one guide rail assembly (5) slides in the up-down direction.

3. The cleaning separation apparatus of claim 2, wherein, The guide rail assembly (5) includes: Support plate (501) is fixedly arranged on the top of the base (1) and is spaced apart from the driving element (3), and a side surface is provided with a sliding rail extending in the up-down direction; Sliding plate (502), the upper end is fixedly connected with the mounting plate (2), and the lower end is provided with a sliding block matched with the sliding rail.

4. The cleaning separation apparatus of claim 3, wherein, The top of the base (1) is provided with a bottom plate (6), and the bottom plate (6) is spaced apart from the mounting plate (2), and the support plate (501) and the driving element (3) are fixedly arranged on the top surface of the bottom plate (6).

5. A cleaning separation apparatus, characterized by Including: The base (1) is further provided with a support shaft (9) on the top, and the cleaning and separating device of any one of claims 1 to 4 is provided; Magnetic suction disc (10) is sleeved on the support shaft (9), and a plurality of magnetic elements are provided around the magnetic suction disc (10), and the magnetic elements are adapted to adsorb magnetic beads in the reaction vessel (13); Rotary mechanism (11) includes rotary driving element (1101) and rotary disc (1102), the rotary disc (1102) is movably sleeved on the support shaft (9), and a plurality of support portions are spaced apart and provided on the end surface of the rotary disc (1102), each support portion is adapted to carry the reaction vessel (13), the rotary driving element (1101) is connected with the rotary disc (1102), and is used to drive the rotary disc (1102) to rotate to the specified position; Cleaning mechanism (12) is arranged on the support shaft (9) and located at the upper end of the rotary disc (1102), and is used to suck and inject liquid into the reaction vessel (13).

6. The cleaning separation apparatus of claim 5, wherein, The cleaning mechanism (12) includes: Liquid injection disc (1201) is sleeved on the support shaft (9) and located at the upper end of the rotary disc (1102), and a plurality of liquid injection portions (1202) are provided on the liquid injection disc (1201) corresponding to the support portions around the liquid injection disc (1201); Lifting driving element (1203) and a plurality of liquid suction portions (1204), the lifting driving element (1203) is arranged on the top of the liquid injection disc (1201), the lifting driving element (1203) is connected with a plurality of liquid suction portions (1204), and is used to drive a plurality of liquid suction portions (1204) to lift, and a plurality of liquid suction portions (1204) correspond to the support portions and are adapted to pass through the liquid injection disc (1201) to enter and exit the reaction vessel (13).

7. The cleaning separation apparatus of claim 6, wherein, The cleaning and separating device is sequentially provided with three-stage liquid injection position, three-stage magnetic suction position and three-stage liquid suction position, and each stage of the magnetic suction position is composed of a plurality of magnetic elements, and each stage of the liquid suction position is arranged above the last magnetic element of each stage of the magnetic suction position.

8. The cleaning separation apparatus of claim 7, wherein, The cleaning and separating device is sequentially provided with an in-out position (101), a first-stage liquid injection position (102), a first-stage magnetic suction position (103), a first-stage liquid suction position (104), a second-stage liquid injection position (105), a second-stage magnetic suction position (106), a second-stage liquid suction position (107), a third-stage liquid injection position (108), a third-stage magnetic suction position (109), a third-stage liquid suction position (110), and a substrate liquid injection position.

9. The cleaning separation apparatus of claim 8, wherein, The substrate liquid injection position comprises a first substrate liquid injection position (111) and a second substrate liquid injection position (112).

10. A sample test analyzer characterized by, The cleaning and separating device according to any one of claims 5 to 9.

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