Veterinary drug preparation filling equipment

By designing an annular nitrogen curtain and a vacuum recovery valve, the oxidation and contamination problems in the liquid veterinary drug filling process were solved, achieving an efficient and sterile filling process and reducing the loss rate of easily oxidized components and the risk of drug contamination.

CN223905342UActive Publication Date: 2026-02-13GUANGDONG GALLOPER VETERINARY PHARMA
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Patent Information

Application Number
CN202520583477.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-28
Publication Date
2026-02-13
Estimated Expiration
2035-03-28

AI Technical Summary

Technical Problem

Traditional filling equipment results in a high rate of loss of potency of easily oxidized components in liquid veterinary drugs, serious splashing and contamination, and drug residues during the filling process leading to contamination of the next batch.

Method used

An annular nitrogen curtain is used to purge air from the bottle before filling, a fan-shaped nozzle is used to reduce liquid splashing, and a vacuum recovery valve is used to recover residual liquid, ensuring that the liquid is filled in a nitrogen environment.

Benefits of technology

It effectively reduces the potency loss rate of easily oxidized components to <1%, prevents drug contamination, and ensures sterility and component stability during the filling process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses veterinary drug preparation filling equipment, which comprises a conveyor belt, a weighing mechanism, a feeding mechanism and a discharging mechanism, and the filling mechanism is arranged above the conveying belt in a lifting mode and comprises a plurality of filling heads communicated with the liquid supply mechanism, fan-shaped nozzles are arranged at the bottom ends of the filling heads, annular nitrogen curtains are arranged on the outer sides of the fan-shaped nozzles, the output ends of the annular nitrogen curtains are vertically arranged downwards, and vacuum recovery valves are communicated with the interiors of the filling heads. Air in a preparation bottle can be exhausted in advance in the filling process through the annular nitrogen curtain, the preparation bottle is filled with nitrogen, splashing of liquid medicine can be effectively reduced through the fan-shaped nozzle, the probability that the liquid medicine makes contact with the air is reduced, the liquid medicine in the filling head can be recycled into the liquid supply mechanism through the vacuum recycling valve, the liquid medicine of the next batch is prevented from being polluted, and the filling efficiency is improved. The liquid medicine is in a nitrogen environment in the whole process from a liquid supply mechanism to filling, and the titer loss rate of easily oxidized components is reduced from 10%-15% to lt; 1%.
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Description

TECHNICAL FIELD

[0001] The utility model relates to the field of veterinary medicine preparation, especially a veterinary medicine preparation filling equipment. BACKGROUND

[0002] Liquid veterinary medicine (such as vaccine, injection, oral liquid, etc.) as the core preparation of modern veterinary medicine, its filling process needs to meet the strict requirements such as high-precision metering, strict sterile control and component stability maintenance.

[0003] Traditional open filling, liquid medicine is exposed to air, oxygen contact area reaches 50-100cm 2 / min, leading to high loss rate of easy-oxidation components (such as vitamin C, some antibiotics) up to 10%-15%; when filling out liquid, liquid medicine splashing also increases the contact area with oxygen, leading to accelerated oxidation; liquid medicine remaining in the filling head during the filling process will be oxidized, which will contaminate the next batch of liquid medicine during filling. UTILITY MODEL CONTENT

[0004] The utility model aims at providing a veterinary medicine preparation filling equipment to solve the above problems.

[0005] According to one aspect of the utility model, a veterinary medicine preparation filling equipment is provided, which comprises: a conveying belt for conveying preparation bottles, the bottom of the conveying belt is provided with a weighing mechanism; a filling mechanism is arranged above the conveying belt, the filling mechanism comprises a plurality of filling heads in communication with a liquid supply mechanism, the bottom end of the filling head is provided with a fan-shaped nozzle, the outer side of the fan-shaped nozzle is provided with an annular nitrogen curtain, the output end of the annular nitrogen curtain is arranged vertically downward, the inside of the filling head is in communication with a vacuum recovery valve; a control mechanism is in signal connection with the conveying belt, the weighing mechanism, the filling mechanism and the liquid supply mechanism; the vacuum recovery valve is in communication with the liquid supply mechanism.

[0006] In some embodiments, the weighing mechanism is a weighing sensor, which weighs the preparation bottles before and after filling and feeds back signals to the control mechanism.

[0007] In some embodiments, the inside of the fan-shaped nozzle is provided on both sides with a flow guide inclined surface coated with a hydrophobic coating; the liquid inlet end cross section of the fan-shaped nozzle is larger than the liquid outlet end cross section.

[0008] In some embodiments, the annular nitrogen curtain comprises an annular micro-pore arranged on the outer side of the fan-shaped nozzle, the annular micro-pore is in communication with a buffer nitrogen tank, and the output end of the annular micro-pore is arranged vertically downward.

[0009] In some embodiments, the inside of the filling head is provided with a vacuum recovery cavity, the vacuum recovery valve is provided in communication with the vacuum recovery cavity, and the vacuum recovery valve is signal connected with the control mechanism.

[0010] In some embodiments, a lifting manipulator is provided above the conveying belt, and the output end of the lifting manipulator is provided with a plurality of the filling heads.

[0011] In some embodiments, the inside of the fan-shaped nozzle is provided with a heating wire.

[0012] In some embodiments, the liquid supply mechanism comprises a liquid storage tank, and the vacuum recovery valve is in communication with the liquid storage tank through a conduit.

[0013] Compared with the prior art, the application has the beneficial effects that:

[0014] The annular nitrogen curtain of the application can discharge the air in the preparation bottle in advance during the filling process, so that the preparation bottle is filled with nitrogen, the fan-shaped nozzle can effectively reduce the splashing of the liquid medicine, the probability of contact between the liquid medicine and the air is reduced, the vacuum recovery valve can recover the liquid medicine in the filling head into the liquid supply mechanism, so as to prevent the liquid medicine from polluting the next batch of liquid medicine, the liquid medicine is in a nitrogen environment (oxygen concentration ≤0.1%) from the liquid supply mechanism to the filling process, and the loss rate of the potency of easily oxidized components (such as vitamins and antibiotics) is reduced from 10%-15% to <1%. BRIEF DESCRIPTION OF DRAWINGS

[0015] Fig. 1 It is a schematic diagram of the filling head of the application;

[0016] Fig. 2 It is a schematic diagram of the longitudinal section structure of the fan-shaped nozzle of the application. DETAILED DESCRIPTION

[0017] The technical solutions in the embodiments of the application will be clearly and completely described below with reference to the drawings in the embodiments of the application. Obviously, the described embodiments are only part of the embodiments of the application, rather than all the embodiments of the application. Based on the embodiments in the application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the application.

[0018] REFERENCE Figs. 1-2The application provides a kind of veterinary medicine preparation filling equipment, comprising: conveyor belt, to convey preparation bottle, the bottom of conveyor belt is provided with weighing mechanism;Filling mechanism is arranged above conveyor belt, filling mechanism includes a plurality of filling head 1 with liquid supply mechanism communication, the bottom end of filling head 1 is provided with fan-shaped nozzle 2, the outside of fan-shaped nozzle 2 is provided with annular nitrogen curtain 3, the output end of annular nitrogen curtain 3 is vertically downward, the inside of filling head 1 is communicated with vacuum recovery valve 4;Control mechanism is connected with conveyor belt, weighing mechanism, filling mechanism and liquid supply mechanism signal;Vacuum recovery valve 4 is communicated with liquid supply mechanism.

[0019] In some embodiments, the weighing mechanism is a weighing sensor, which weighs the preparation bottle before and after filling and feeds back signals to the control mechanism, automatically calculates the net weight before and after filling, and controls the start and stop of the filling mechanism through signal feedback.

[0020] In some embodiments, the inside of the fan-shaped nozzle 2 is inclinedly provided with a flow guide slope 5 on both sides, and the flow guide slope 5 is coated with a hydrophobic coating; the liquid inlet end 6 of the fan-shaped nozzle 2 has a larger cross section than the liquid outlet end 7, and the end of the fan-shaped nozzle 2 is a flat slit (width 0.5-2mm), which makes the liquid spread in a fan shape, the flat outlet diffuses the liquid into a fan-shaped liquid film, ensures that the liquid accurately falls into the bottle, and the hydrophobic coating can make the residual liquid <0.01mL / time, and the larger cross section of the liquid inlet end 6 than the liquid outlet end 7 can make the liquid fill the liquid outlet end 7, and the liquid flow is more stable, and the liquid flow stability is improved.

[0021] In some embodiments, the annular nitrogen curtain 3 includes an annular micro-hole arranged outside the fan-shaped nozzle 2, the annular micro-hole is communicated with a buffer nitrogen tank, and the output end of the annular micro-hole is vertically downward; the annular micro-hole is designed around the outside of the fan-shaped nozzle 2, and the aperture is usually 0.1-0.3mm; the nitrogen is uniformly sprayed downward to form a cylindrical gas barrier, which always ensures that the liquid is in the cylindrical gas barrier during filling.

[0022] In some embodiments, the inside of the filling head 1 is provided with a vacuum recovery cavity, the vacuum recovery valve 4 is communicated with the vacuum recovery cavity, the vacuum recovery valve 4 is signal connected with the control mechanism, and the vacuum recovery valve 4 starts-0.05MPa negative pressure suction of residual liquid at the moment of filling end, and the recovered liquid is returned to the liquid supply mechanism after ultraviolet sterilization.

[0023] In some embodiments, the top of the conveyor belt is provided with a lifting manipulator, and the output end of the lifting manipulator is provided with a plurality of filling heads 1.

[0024] In some embodiments, the inside of the fan-shaped nozzle 2 is provided with a heating wire, which is controlled at 30-50℃ to prevent high-concentration liquid from crystallizing and blocking at low temperature.

[0025] In some embodiments, the liquid supply mechanism comprises a liquid storage tank, and the vacuum recovery valve 4 is in communication with the liquid storage tank through a conduit.

[0026] The specific filling process of the present application: the empty preparation bottle is moved under the filling mechanism by the conveying belt, the lifting manipulator drives multiple filling heads 1 to move downward at the same time and the lower part of the filling head 1 enters the preparation bottle, the annular nitrogen curtain 3 outputs nitrogen vertically downward and gradually discharges the air in the preparation bottle, after a preset exhaust time, the liquid supply mechanism supplies liquid to the filling head 1, the liquid is discharged through the fan-shaped nozzle 2, and the lifting manipulator drives the filling head 1 to gradually rise with the liquid level during the discharge process. When the weighing mechanism receives feedback information of a certain weight, the control mechanism controls the liquid supply mechanism to temporarily stop supplying liquid, the vacuum recovery valve 4 is started instantly at-0.05 MPa negative pressure to suck the residual liquid, the recovered liquid is returned to the liquid supply mechanism after ultraviolet sterilization, and the preparation bottle loaded with liquid enters the next station with the conveying belt.

[0027] The annular nitrogen curtain 3 of the present application can discharge the air in the preparation bottle in advance during the filling process, so that it is filled with nitrogen, the fan-shaped nozzle 2 can effectively reduce the splashing of the liquid, reduce the probability of contact between the liquid and the air, the vacuum recovery valve 4 can recover the liquid in the filling head 1 to the liquid supply mechanism, prevent the pollution of the next batch of liquid, and the liquid is in a nitrogen environment (oxygen concentration ≤0.1%) from the liquid supply mechanism to the filling process. The loss rate of the potency of easily oxidizable components (such as vitamins and antibiotics) is reduced from 10%-15% to <1%.

[0028] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and not for limiting the present application, although the present application has been described in detail with reference to the foregoing embodiments, for those skilled in the art, it still can modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part of the technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A veterinary drug preparation filling equipment, characterized in that, include: A conveyor belt for conveying preparation bottles, wherein a weighing mechanism is provided at the bottom of the conveyor belt; A filling mechanism is lifted and positioned above the conveyor belt. The filling mechanism includes multiple filling heads that are connected to the liquid supply mechanism. A fan-shaped nozzle is provided at the bottom of the filling head. An annular nitrogen curtain is provided on the outside of the fan-shaped nozzle. The output end of the annular nitrogen curtain is vertically downward. A vacuum recovery valve is connected inside the filling head. The control mechanism is signal-connected to the conveyor belt, weighing mechanism, filling mechanism, and liquid supply mechanism; the vacuum recovery valve is connected to the liquid supply mechanism.

2. The veterinary drug preparation filling equipment according to claim 1, characterized in that, The weighing mechanism is a weighing sensor, which weighs the preparation bottles before and after filling and feeds back the signal to the control mechanism.

3. The veterinary drug preparation filling equipment according to claim 1, characterized in that, The fan-shaped nozzle has inclined guide surfaces on both sides inside, and the guide surfaces are coated with a hydrophobic coating; the cross-section of the liquid inlet end of the fan-shaped nozzle is larger than the cross-section of the liquid outlet end.

4. The veterinary drug preparation filling equipment according to claim 1, characterized in that, The annular nitrogen curtain includes annular micro-holes disposed outside the fan-shaped nozzle. The annular micro-holes are connected to a buffer nitrogen tank, and the output end of the annular micro-holes is vertically downward.

5. The veterinary drug preparation filling equipment according to claim 1, characterized in that, The filling head has an internally connected vacuum recovery chamber, and the vacuum recovery valve is connected to the vacuum recovery chamber and is signal-connected to the control mechanism.

6. The veterinary drug preparation filling equipment according to claim 1, characterized in that, A lifting robot arm is installed above the conveyor belt, and multiple filling heads are installed at the output end of the lifting robot arm.

7. The veterinary drug preparation filling equipment according to claim 1, characterized in that, The fan-shaped nozzle is equipped with a heating wire inside.

8. The veterinary drug preparation filling equipment according to claim 1, characterized in that, The liquid supply mechanism includes a liquid storage tank, and the vacuum recovery valve is connected to the liquid storage tank via a conduit.