Electrophoresis apparatus for cell culture analysis

Abstract

The utility model relates to the technical field of electrophoresis apparatuses, and discloses an electrophoresis apparatus for cell culture analysis, which comprises an electrophoresis apparatus, the top of the outer wall of the electrophoresis apparatus is provided with a mounting groove, the front side and the rear side of the inner wall of the mounting groove are fixedly connected with a plurality of positioning blocks, the adjacent sides of the positioning blocks are slidably connected with a gel box, and the gel box is provided with a plurality of gel holes. Wires are fixedly connected to the left side and the right side of the bottom of the outer wall of the gel box, wire interfaces are formed in the left side and the right side of the top of the electrophoresis apparatus, supporting blocks are fixedly connected to the periphery of the bottom of the inner wall of the gel box, and gel plates are slidably connected to the adjacent sides of the multiple supporting blocks. According to the utility model, the gel box stably slides into the mounting groove along the positioning block, so that the conduction of current can be quickly realized, ultraviolet rays emitted by the ultraviolet disinfection lamp can disinfect the gel box, and air flow generated by the operation of the fan can blow water stains on the gel box dry, so that the gel box is kept dry and bacteria are prevented from breeding.

Description

TECHNICAL FIELD

[0001] The utility model relates to electrophoresis apparatus technical field especially relates to a cell culture analysis's electrophoresis apparatus. BACKGROUND

[0002] Electrophoresis technology is indispensable important analysis means of molecular biology research, under the action of direct current electric field, charged particle will move to the electrode direction opposite to its charge, different biological macromolecules due to its molecular weight, charge property and quantity factor's difference, need to use a cell culture analysis's electrophoresis apparatus in cell culture analysis.

[0003] Cell culture analysis's electrophoresis apparatus can separate the protein and nucleic acid biological macromolecule in cell extract, through the research to cell electrophoresis behavior, can understand the surface charge and membrane structure's characteristics of cell.

[0004] The common cell culture analysis's electrophoresis apparatus on market places in the use process after placing good gel box, uses the wire and communicates electrophoresis apparatus with gel box, puts into buffer solution in gel box and analyzes sample, due to more preparation work and the manual cleaning after using gel box, the operation process is complex and can not automatically disinfect gel box. UTILITY MODEL CONTENT

[0005] In order to make up the above insufficient, the utility model provides a cell culture analysis's electrophoresis apparatus, aims at improving the operation process complex and can not automatically disinfect gel liquid's problem in prior art.

[0006] In order to realize above -mentioned purpose, the utility model adopts the following technical scheme: a cell culture analysis's electrophoresis apparatus, including electrophoresis apparatus, the outer wall top of electrophoresis apparatus is equipped with the mounting slot, the inner wall front and back of mounting slot are all fixedly connected with a plurality of positioning blocks, the adjacent side of positioning block is slidably connected with gel box, the outer wall bottom of gel box is all fixedly connected with wire on left and right sides, the top left and right sides of electrophoresis apparatus are equipped with wire interface, the inner wall bottom of gel box is all fixedly connected with support block around, the adjacent side of a plurality of support blocks is slidably connected with gel plate, the top right side of gel plate is equipped with a plurality of sample application holes, the top rear side of wire is rotatably connected with lid, the top rear side of electrophoresis apparatus is rotatably connected with cover plate, the outer wall front end of cover plate is all fixedly connected with ultraviolet disinfection lamp on left and right sides, the outer wall end of cover plate is all fixedly connected with fan on left and right sides, the outside of electrophoresis apparatus is slidably connected with protection box, the inner wall bottom of protection box is provided with lifting mechanism, and the lifting mechanism is used to adjust the height of electrophoresis apparatus.

[0007] As the further description of the above scheme:

[0008] The lifting mechanism comprises a fixed frame, the fixed frame is fixedly connected to the inner wall bottom of the protection box, the inner wall left and right sides of the fixed frame are rotationally connected with threaded rods, the inner wall left and right sides of the fixed frame are slidably connected with T-shaped blocks, the T-shaped blocks are threadedly connected with the fixed frame, the inner wall of the T-shaped block is rotationally connected with a supporting rod, the other end of the supporting rod is rotationally connected with a sliding block, the top of the sliding block is slidably connected with a lifting plate, the electrophoresis instrument is arranged above the lifting plate, the lifting plate is slidably connected with the protection box, the bottom of the lifting plate is fixedly connected with vertical rods, the bottom of the protection box is slidably connected with moving wheels, the top of the moving wheels penetrates the protection box and is fixedly connected with a stop block, springs are arranged on the outer side of the moving wheels, and the bottom end of the spring is fixedly connected with the protection box.

[0009] As a further description of the above scheme:

[0010] The outer wall front end left side of the electrophoresis instrument is fixedly connected with a display screen, and the outer wall front end right side of the electrophoresis instrument is fixedly connected with a plurality of control buttons.

[0011] As a further description of the above scheme:

[0012] The outer wall right side of the protection box is provided with a push handle, the outer wall left and right sides of the push handle are threadedly connected with screws, and the push handle is threadedly connected with the protection box through the screws.

[0013] As a further description of the above scheme:

[0014] The top of the protection box is rotationally connected with a box cover, the top left and right sides of the box cover are fixedly connected with hooks, the front end top left and right sides of the protection box are fixedly connected with buckles, and the buckles are clamped with the hooks.

[0015] As a further description of the above scheme:

[0016] The right end of the threaded rod is fixedly connected with a handle, and the outer wall of the handle is fixedly connected with an anti-skid sleeve.

[0017] As a further description of the above scheme:

[0018] The outer wall left and right sides of the protection box are fixedly connected with a plurality of limiting blocks, the inner wall left and right sides of the protection box are provided with a plurality of sliding grooves, and the limiting blocks are slidably connected with the sliding grooves.

[0019] As a further description of the above scheme:

[0020] The top front side of the electrophoresis instrument is provided with a reserved slot, and a plurality of partition plates are fixedly connected to the inner wall left and right sides of the reserved slot at equal intervals.

[0021] The utility model has the advantages that:

[0022] 1、The utility model discloses a gel box is slid along the positioning block steadily into the installation groove, and the wire is connected with the wire interface on the left and right sides of the top of the electrophoresis instrument, realizes the conduction of the current quickly, the ultraviolet light of ultraviolet disinfection lamp can reach the purpose of disinfection, and the airflow generated by the operation of the fan can blow the water stain on the gel box, thereby making the gel box keep dry, preventing the breeding of bacteria, and solving the problems of complex operation process and the incapability of automatically disinfecting the gel box.

[0023] 2、The utility model discloses a rotating screw rod can realize the lifting of electrophoresis instrument, needs using electrophoresis instrument, rotates screw rod and drives electrophoresis instrument to rise and makes the protection case low simultaneously with the retraction of the moving wheel, improves the stability of the device, needs moving electrophoresis instrument, rotates screw rod and makes electrophoresis instrument retract simultaneously with the extrusion of the vertical rod, and the moving wheel stretches out and contacts the ground, and the protection case leaves the ground, thereby facilitating the movement of the device, and the practicality of the device is improved. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 It is a perspective view of the electrophoresis instrument for cell culture analysis that the utility model proposes;

[0025] Figure 2 It is a front view of the electrophoresis instrument for cell culture analysis that the utility model proposes;

[0026] Figure 3 It is a split view of the electrophoresis instrument for cell culture analysis that the utility model proposes;

[0027] Figure 4 It is the lifting structure schematic diagram of the electrophoresis instrument for cell culture analysis that the utility model proposes;

[0028] Figure 5 It is the local structure schematic diagram of the electrophoresis instrument for cell culture analysis that the utility model proposes.

[0029] LEGEND:

[0030] 1, electrophoresis apparatus; 2, lifting mechanism; 201, fixed frame; 202, threaded rod; 203, T-shaped block; 204, support rod; 205, sliding block; 206, lifting plate; 207, vertical rod; 208, moving wheel; 209, stop block; 210, spring; 3, mounting groove; 4, positioning block; 5, gel box; 6, wire; 7, wire interface; 8, support block; 9, gel plate; 10, sample application hole; 11, cover; 12, cover plate; 13, ultraviolet disinfection lamp; 14, fan; 15, protective box; 16, display screen; 17, control button; 18, push handle; 19, screw; 20, buckle; 21, hook; 22, box cover; 23, handle; 24, anti-skid sleeve; 25, limiting block; 26, sliding groove; 27, reserved groove; 28, partition. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the protection scope of the utility model.

[0032] With reference to Figure 1 , Figure 2 and Figure 3 , an embodiment provided by the utility model: an electrophoresis apparatus for cell culture analysis, comprising an electrophoresis apparatus 1, the outer wall top of the electrophoresis apparatus 1 is provided with a mounting groove 3, the inner wall of the mounting groove 3 is fixedly connected with a plurality of positioning blocks 4 on the front and rear sides, the positioning block 4 plays a guiding and fixing role, the adjacent side of the positioning block 4 is slidably connected with a gel box 5, the outer wall bottom of the gel box 5 is fixedly connected with wires 6 on the left and right sides, the top left and right sides of the electrophoresis apparatus 1 are provided with wire interfaces 7, the inner wall bottom of the gel box 5 is fixedly connected with support blocks 8 on all around, the support block 8 provides support for a gel plate 9, the adjacent side of a plurality of support blocks 8 is slidably connected with the gel plate 9, the top right side of the gel plate 9 is provided with a plurality of sample application holes 10, the top rear side of the wire 6 is rotatably connected with a cover 11, the top rear side of the electrophoresis apparatus 1 is rotatably connected with a cover plate 12, the outer wall front end of the cover plate 12 is fixedly connected with ultraviolet disinfection lamps 13 on the left and right sides, the ultraviolet rays emitted by the ultraviolet disinfection lamp 13 can penetrate components such as the gel box 5 and the gel plate 9, so as to achieve the purpose of disinfection, the outer wall end of the cover plate 12 is fixedly connected with fans 14 on the left and right sides, the fan 14 starts to operate, the airflow generated can blow dry the water stains on the gel box 5, so that the gel box 5 remains dry, preventing the breeding of bacteria, the outer side of the electrophoresis apparatus 1 is slidably provided with a protective box 15, the inner wall bottom of the protective box 15 is provided with a lifting mechanism 2, the lifting mechanism 2 is used for adjusting the height of the electrophoresis apparatus 1;

[0033] Specific, the positioning block 4 in the installation groove 3 plays a guiding and fixed role, the gel box 5 is smoothly slid into the installation groove 3 along the positioning block 4, so that the gel box 5 can be accurately installed on the electrophoresis instrument 1 and will not be displaced during the electrophoresis process, the gel box 5 is connected with the wire interface 7 on the top left and right sides of the electrophoresis instrument 1 through the wires 6 on the bottom left and right sides of the gel box 5, so that the current is turned on, the support blocks 8 around the inner wall bottom of the gel box 5 provide support for the gel plate 9, and the gel plate 9 is placed on the support blocks 8, so that it can stably be in the gel box 5, the sample application hole 10 on the top right side of the gel plate 9 is used to add the cell culture sample to be analyzed, after the electrophoresis experiment is completed, the ultraviolet disinfection lamp 13 emits ultraviolet rays that can penetrate the gel box 5, the gel plate 9 and other components to destroy the DNA structure of bacteria and microorganisms, so as to achieve the purpose of disinfection, the fan 14 on the cover plate 12 starts to operate, and the airflow generated can blow dry the water stains on the gel box 5, so that the gel box 5 remains dry and prevents the growth of bacteria.

[0034] With reference to Figure 1 , Figure 2 and Figure 4 , the lifting mechanism 2 comprises a fixed frame 201 fixedly connected to the inner wall bottom of the protection box 15, screw rods 202 rotatably connected to the inner wall left and right sides of the fixed frame 201, a T-shaped block 203 slidably connected to the inner wall left side of the fixed frame 201, the T-shaped block 203 being threadedly connected with the fixed frame 201, the screw rods 202 being rotated to drive the T-shaped block 203 to slide, a support rod 204 rotatably connected to the inner wall of the T-shaped block 203, a sliding block 205 rotatably connected to the other end of the support rod 204, a lifting plate 206 slidably connected to the top of the sliding block 205, when the T-shaped block 203 moves in a specific direction, the angle of the support rod 204 becomes larger, which generates a vertical pushing force on the sliding block 205, the sliding block 205 slides on the bottom of the lifting plate 206, and due to the pushing force of the support rod 204, the sliding block 205 slides on the bottom of the lifting plate 206 in a direction that makes the lifting plate 206 rise, the electrophoresis instrument 1 is arranged above the lifting plate 206, the lifting plate 206 is slidably connected with the protection box 15, vertical rods 207 are fixedly connected to the bottom of the lifting plate 206, moving wheels 208 are slidably connected to the bottom of the protection box 15, stop blocks 209 are fixedly connected to the top of the moving wheels 208 and penetrate the protection box 15, springs 210 are arranged on the outer side of the moving wheels 208 and have bottom ends fixedly connected to the protection box 15, when the vertical rods 207 move away from the stop blocks 209, the springs 210 lose the pressure constraint of the vertical rods 207 and push the stop blocks 209 upward to drive the moving wheels 208 to rise, so that the protection box 15 touches the ground and the position of the protection box 15 is fixed, reverse rotation of the screw rods 202 drives the vertical rods 207 to descend and press the stop blocks 209, so that the moving wheels 208 contact the ground and the protection box 15 can be easily pushed;

[0035] Specifically, rotating the threaded rod 202 drives the T-shaped block 203 to slide. When the T-shaped block 203 moves in a specific direction, the angle of the supporting rod 204 increases, which generates a vertical pushing force on the sliding block 205. The sliding block 205 slides on the bottom of the lifting plate 206 and moves in the direction that makes the lifting plate 206 rise due to the pushing force of the supporting rod 204. The movement of the sliding block 205 drives the lifting plate 206 to slide up and down in the protection box 15. With the lifting plate 206 moving up and down, the vertical rod 207 fixedly connected to the bottom of the lifting plate 206 also moves. When the vertical rod 207 moves away from the stop block 209, the spring 210 loses the pressure constraint of the vertical rod 207 and pushes the stop block 209 to move upward, thereby driving the moving wheel 208 to rise, making the protection box 15 touch the ground and fixing the position of the protection box 15. Rotating the threaded rod 202 in the opposite direction drives the vertical rod 207 to descend and press the stop block 209, so that the moving wheel 208 contacts the ground and the protection box 15 can be easily pushed.

[0036] Referring to Figure 1 , Figure 3 and Figure 5 , the front left side of the outer wall of the electrophoresis instrument 1 is fixedly connected with a display screen 16, which is used to display the working state parameters of the electrophoresis instrument. The front right side of the outer wall of the electrophoresis instrument 1 is fixedly connected with a plurality of control buttons 17, which are used to set and adjust the working parameters of the electrophoresis instrument. The right side of the outer wall of the protection box 15 is provided with a push handle 18. The left and right sides of the outer wall of the push handle 18 are both threadedly connected with screws 19. The push handle 18 is threadedly connected with the protection box 15 through the screws 19. The push handle 18 provides a handheld part, which facilitates the operator to move the entire equipment. The top of the protection box 15 is rotatably connected with a box cover 22. The top of the box cover 22 is fixedly connected with hooks 21 on the left and right sides. The front top of the protection box 15 is fixedly connected with buckles 20 on the left and right sides. The buckles 20 are engaged with the hooks 21. The hooks 21 and the buckles 20 are used to fix the box cover 22, so as to ensure that the box cover 22 will not be accidentally opened in the closed state.

[0037] Specifically, the display screen 16 is used to display the working state parameters of the electrophoresis instrument, which can enable the operator to intuitively understand the running condition of the electrophoresis instrument, so as to timely adjust the parameters or find problems. The control buttons 17 are used to set and adjust the working parameters of the electrophoresis instrument. The push handle 18 provides a handheld part, which facilitates the operator to move the entire equipment. When the electrophoresis instrument 1 is not in use, the box cover 22 can be closed to protect the protection box 15, preventing dust, debris, etc. from entering the inside of the protection box 15, which plays a protective role for the electrophoresis instrument 1. The hooks 21 and the buckles 20 are used to fix the box cover 22, so as to ensure that the box cover 22 will not be accidentally opened in the closed state.

[0038] Referring to Figure 1 , Figure 3 and Figure 5The right end of the threaded rod 202 is fixedly connected with a handle 23, the handle 23 facilitates an operator to rotate the threaded rod 202, the outer wall of the handle 23 is fixedly connected with an anti-skid sleeve 24, the anti-skid sleeve 24 increases the friction of the handle 23; the outer wall of the protection box 15 is fixedly connected with a plurality of limiting blocks 25 on the left and right sides, the inner wall of the protection box 15 is provided with a plurality of sliding grooves 26 on the left and right sides, the limiting blocks 25 are slidingly connected with the sliding grooves 26, and the limiting blocks 25 position and guide the up-down movement of the electrophoresis instrument 1; the top front side of the electrophoresis instrument 1 is provided with a reserved groove 27, the inner wall of the reserved groove 27 is fixedly connected with a plurality of partition plates 28 at equal intervals on the left and right sides, the reserved groove 27 can be used for placing some experimental related articles, the partition plates 28 separate and arrange the articles placed in the reserved groove 27, and mutual collision or confusion of the articles is prevented;

[0039] Specifically, the handle 23 facilitates an operator to rotate the threaded rod 202, thereby adjusting the height of the lifting mechanism 2, the anti-skid sleeve 24 increases the friction of the handle 23, and hand slipping is prevented when the handle 23 is rotated; the limiting blocks 25 position and guide the up-down movement of the electrophoresis instrument 1, and the electrophoresis instrument 1 remains stable during lifting and is prevented from tilting or deviating; the reserved groove 27 can be used for placing some experimental related articles, and the partition plates 28 separate and arrange the articles placed in the reserved groove 27, and mutual collision or confusion of the articles is prevented.

[0040] Working principle: before using the device, first of all, the gel box 5 is stably slid into the mounting groove 3 along the positioning block 4, the gel box 5 is accurately mounted on the electrophoresis instrument 1, the wire 6 is connected with the wire interface 7 on the left and right sides of the top of the electrophoresis instrument 1, so that the conduction of the current is realized, the gel plate 9 is placed on the supporting block 8, the sample application hole 10 on the top right side of the gel plate 9 is used for adding a cell culture sample to be analyzed, when the electrophoresis experiment is completed, the ultraviolet disinfection lamp 13 emits ultraviolet rays that can penetrate components such as the gel box 5 and the gel plate 9, destroy the DNA structure of bacteria and microorganisms, and thus the purpose of disinfection is achieved, the fan 14 on the cover plate 12 starts to operate, and the airflow generated can blow dry the water stains on the gel box 5, so that the gel box 5 remains dry and bacteria are prevented from breeding;

[0041] And by rotating the threaded rod 202 to drive the T-shaped block 203 to slide, the T-shaped block 203 moves to a specific direction to make the support rod 204 angle larger, the sliding block 205 generates a vertical direction thrust, the movement of the sliding block 205 drives the lifting plate 206 to slide up and down in the protection box 15, with the lifting plate 206 up and down movement, the vertical rod 207 fixedly connected at the bottom of the lifting plate 206 also moves, when the vertical rod 207 moves away from the stop block 209, the spring 210 loses the pressure constraint of the vertical rod 207 to push the stop block 209 to move upward to drive the moving wheel 208 to rise, so that the protection box 15 lands, thereby fixing the position of the protection box 15, reverse rotation of the threaded rod 202 drives the vertical rod 207 to descend to extrude the stop block 209, so that the moving wheel 208 contacts the ground, the protection box 15 can be easily pushed.

[0042] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and not for limiting the present application, although the foregoing detailed description of the present application is made with reference to the foregoing embodiments, for the skilled in the art, it still can be modified, or for part of the technical features of the equivalent replacement, within the spirit and principles of the present application, any modification, equivalent replacement, improvement, etc., should be included in the scope of protection of the present application.

Claims

1. An electrophoresis apparatus for cell culture analysis comprising an electrophoresis apparatus (1), characterized in that: The electrophoresis apparatus (1) has a mounting groove (3) on the top of its outer wall. Multiple positioning blocks (4) are fixedly connected to the front and rear sides of the inner wall of the mounting groove (3). A gel box (5) is slidably connected to an adjacent side of each positioning block (4). Wires (6) are fixedly connected to the left and right sides of the bottom of the outer wall of the gel box (5). Wire interfaces (7) are provided on the left and right sides of the top of the electrophoresis apparatus (1). Support blocks (8) are fixedly connected to the four sides of the bottom of the inner wall of the gel box (5). A gel plate (9) is slidably connected to an adjacent side of each support block (8). The top of the gel plate (9)... Multiple sample holes (10) are provided on the right side. A cover (11) is rotatably connected to the top rear side of the wire (6). A cover plate (12) is rotatably connected to the top rear side of the electrophoresis apparatus (1). Ultraviolet disinfection lamps (13) are fixedly connected to the left and right sides of the front end of the outer wall of the cover plate (12). Fans (14) are fixedly connected to the left and right sides of the outer wall of the cover plate (12). A protective box (15) slides on the outside of the electrophoresis apparatus (1). A lifting mechanism (2) is provided at the bottom of the inner wall of the protective box (15). The lifting mechanism (2) is used to adjust the height of the electrophoresis apparatus (1).

2. The electrophoresis apparatus for cell culture analysis according to claim 1, characterized by: The lifting mechanism (2) includes a fixed frame (201), which is fixedly connected to the bottom of the inner wall of the protective box (15). Threaded rods (202) are rotatably connected to the left and right sides of the inner wall of the fixed frame (201). T-blocks (203) are slidably connected to the left and right sides of the inner wall of the fixed frame (201). The T-blocks (203) are threadedly connected to the fixed frame (201). A support rod (204) is rotatably connected to the inner wall of the T-blocks (203). A sliding block (205) is rotatably connected to the other end of the support rod (204). The top of the sliding block (205) is slidably connected to... A lifting plate (206) is connected to the electrophoresis apparatus (1), which is located above the lifting plate (206). The lifting plate (206) is slidably connected to the protective box (15). Uprights (207) are fixedly connected to the bottom of the lifting plate (206). Moving wheels (208) are slidably connected to the bottom of the protective box (15). The top of the moving wheel (208) passes through the protective box (15) and is fixedly connected to a stop block (209). A spring (210) is provided on the outside of the moving wheel (208), and the bottom end of the spring (210) is fixedly connected to the protective box (15).

3. The electrophoresis apparatus for cell culture analysis according to claim 1, characterized by: A display screen (16) is fixedly connected to the left side of the front end of the outer wall of the electrophoresis apparatus (1), and multiple control buttons (17) are fixedly connected to the right side of the front end of the outer wall of the electrophoresis apparatus (1).

4. The electrophoresis apparatus for cell culture analysis according to claim 1, characterized by: A push handle (18) is provided on the right side of the outer wall of the protective box (15). Screws (19) are threadedly connected to the left and right sides of the outer wall of the push handle (18). The push handle (18) is threadedly connected to the protective box (15) through the screws (19).

5. The electrophoresis apparatus for cell culture analysis according to claim 1, characterized by: The top of the protection box (15) is rotationally connected with a box cover (22), the top of the box cover (22) is fixedly connected with hooks (21) on the left and right sides, the top of the front end of the protection box (15) is fixedly connected with buckles (20) on the left and right sides, and the buckles (20) are clamped with the hooks (21).

6. The electrophoresis apparatus for cell culture analysis according to claim 2, characterized by: The right end of the threaded rod (202) is fixedly connected with a handle (23), and the outer wall of the handle (23) is fixedly connected with a non-slip sleeve (24).

7. The electrophoresis apparatus for cell culture analysis according to claim 1, characterized by: The left and right sides of the outer wall of the protection box (15) are fixedly connected with a plurality of limiting blocks (25), and the left and right sides of the inner wall of the protection box (15) are provided with a plurality of sliding grooves (26), and the limiting blocks (25) are slidably connected with the sliding grooves (26).

8. The electrophoresis apparatus for cell culture analysis according to claim 1, characterized by: The top of the electrophoresis instrument (1) is provided with a reserved groove (27) on the front side, and a plurality of partition plates (28) are fixedly connected to the inner wall of the reserved groove (27) on the left and right sides at equal intervals.

Images