Cell proliferation dynamic monitoring device based on electrical impedance technology

Abstract

The utility model relates to the field of cell monitoring equipment, and discloses a cell proliferation dynamic monitoring device based on an electrical impedance technology, the cell proliferation dynamic monitoring device comprises an illuminating lamp, three limiting frames and a cell analysis monitor, the top of the cell analysis monitor is provided with the limiting frames, the three limiting frames are internally and movably provided with filter lenses, and the filter lenses are arranged in the limiting frames. The top of the cell analysis monitor on the periphery of the limiting frame is fixedly connected with a supporting rod, the top of the supporting rod is movably provided with a limiting plate, the bottom of the limiting plate is fixedly connected with a limiting rod, the bottom of the limiting rod is fixedly connected with a magnetic attraction block, and an illuminating lamp is embedded in the limiting plate. The fluorescence filter and the polarization filter are combined, so that the analysis accuracy and definition are improved, background interference is reduced, the optical characteristics of cells are revealed, the positions of the filters are flexibly adjusted, the analysis precision is improved, the sensitivity and specificity of fluorescence signals are enhanced in cooperation with an adjustable wavelength illuminating lamp, and the detection efficiency and adaptability are improved through optimal design.

Description

Technical Field

[0001] This application relates to the field of cell monitoring equipment technology, and in particular to a cell proliferation dynamic monitoring device based on electrical impedance technology. Background Technology

[0002] The cell proliferation dynamic monitoring device based on electrical impedance technology is a device that assesses cell proliferation by monitoring changes in electrical impedance during cell growth in real time. The device measures the changes in electrical impedance generated when cells come into contact with the electrode surface by implanting microelectrodes in the culture medium. The electrical impedance signal changes accordingly with changes in cell number and growth status.

[0003] Currently, existing cell proliferation dynamic monitoring devices based on electrical impedance technology lack filters and lighting structures to assist in monitoring, making it difficult for staff to monitor cells that require special light sources and fluorescence filters. Utility Model Content

[0004] To address the problems mentioned in the background art, this application provides a cell proliferation dynamic monitoring device based on electrical impedance technology.

[0005] The cell proliferation dynamic monitoring device based on electrical impedance technology provided in this application adopts the following technical solution:

[0006] A cell proliferation dynamic monitoring device based on electrical impedance technology includes a lighting lamp, a limiting frame, and a cell analysis monitor. The cell analysis monitor has a limiting frame installed on its top, and there are three limiting frames. Filter lenses are movably installed inside the three limiting frames. A support rod is fixedly connected to the top of the cell analysis monitor around the limiting frame. A limiting plate is movably installed on the top of the support rod. A limiting rod is fixedly connected to the bottom of the limiting plate. A magnetic block is fixedly connected to the bottom of the limiting rod. A lighting lamp is embedded inside the limiting plate.

[0007] Preferably, the support rod has a slot inside, and the limiting rod is fitted into the slot.

[0008] Preferably, one end of the support rod is fixedly connected to a protective shell, and the filter element penetrates the protective shell.

[0009] Preferably, one end of the filter element is fixedly connected to a pull block, and the pull block is made of aluminum alloy.

[0010] Preferably, a pull frame is fixedly connected to the other end of the filter element, and the pull frame is made of silicone rubber.

[0011] In summary, this application includes the following beneficial technical effects:

[0012] By combining fluorescence and polarization filters, the accuracy and clarity of cell sample analysis are effectively enhanced. The fluorescence filter effectively separates excitation and emission light, reducing background interference and making the fluorescence characteristics of cells more prominent. The polarization filter provides a new dimension of the optical properties of cells, which helps to study the physical and chemical properties of cells in depth. Staff can flexibly adjust the position of the filter pieces according to their needs, thereby improving the accuracy of analysis. The adjustable wavelength illumination lamp provides a precise excitation source, further improving the sensitivity and specificity of the fluorescence signal and ensuring the accuracy of cell activity, protein expression, and other detections. Through the above optimized design, the device not only improves detection efficiency but also reduces operational limitations and is more adaptable. Attached Figure Description

[0013] Figure 1 This is an overall perspective view of the embodiment of the application;

[0014] Figure 2 This is a rear view of an embodiment of the application;

[0015] Figure 3 This is a partial structural diagram of the slot and magnetic block in the embodiment of the application.

[0016] Explanation of reference numerals in the attached drawings: 1. Lighting lamp; 2. Limiting plate; 3. Limiting frame; 4. Cell analysis monitor; 5. Filter lens; 501. Pull block; 502. Pull frame; 6. Protective shell; 7. Support rod; 701. Slot; 8. Limiting rod; 801. Magnetic block. Detailed Implementation

[0017] The following is in conjunction with the appendix Figure 1-3 This application will be described in further detail.

[0018] This application discloses a cell proliferation dynamic monitoring device based on electrical impedance technology. (Refer to...) Figure 1-3A cell proliferation dynamic monitoring device based on electrical impedance technology includes an illumination lamp 1, a limiting frame 3, and a cell analysis monitor 4. The cell analysis monitor 4 has three limiting frames 3 mounted on its top. Filter lenses 5 are movably installed inside each limiting frame 3. A support rod 7 is fixedly connected to the top of the cell analysis monitor 4 surrounding the limiting frames 3. A limiting plate 2 is movably installed on the top of the support rod 7. A limiting rod 8 is fixedly connected to the bottom of the limiting plate 2, and a magnetic block 801 is fixedly connected to the bottom of the limiting rod 8. The illumination lamp 1 is embedded inside the limiting plate 2. The cell analysis monitor 4 is a conventional cell analyzer in this technical field. The operator connects the cell analysis monitor 4 to an external analysis software host, places the cell monitoring sample on top of the cell analysis monitor 4 inside the limiting frame 3, and uses the cell analysis monitor 4 to analyze and monitor the cell sample. The front half of the filter lens 5 is a fluorescence filter, which can effectively separate excitation light and emission light. The light enhances the accuracy and clarity of fluorescence detection, reduces background interference, and makes the fluorescence characteristics of cells more obvious. The rear half of the filter 5 is a polarizing filter, which can reveal some special optical properties of cells, providing new dimensions and information for cell analysis and helping to study the physical and chemical properties of cells in depth. According to the detection needs of cell samples, the staff can insert the filter 5 into the inside of the limiting frame 3 and pull to adjust the position of the filter 5, so that the device can analyze and monitor more cell samples better and more accurately, reducing the limitations of the device. The staff can also install the limiting plate 2 on the top of the support rod 7 to install the lighting lamp 1 on the top of the limiting frame 3. The magnetic block 801 can be attracted and connected to the metal support rod 7. The lighting lamp 1 is an adjustable wavelength light source that can accurately excite specific fluorescence, improve the specificity and sensitivity of detection, and help to more accurately obtain the fluorescence signal of cells, thereby conducting analysis of cell activity, protein expression, etc.

[0019] Reference Figure 3 The support rod 7 has a slot 701 inside, and the limiting rod 8 is fitted into the slot 701. Inserting the limiting rod 8 into the slot 701 increases the friction between the limiting rod 8 and the support rod 7, thereby improving the stability of the installation of the limiting plate 2.

[0020] Reference Figure 2 One end of the support rod 7 is fixedly connected to the protective shell 6, and the filter element 5 passes through the protective shell 6. The protective shell 6 can protect the filter element 5 and prevent the filter element 5 from getting too dusty when it is not in use.

[0021] Reference Figure 1 One end of the filter element 5 is fixedly connected to a pull block 501, which is made of aluminum alloy. The operator holds the pull block 501 and pulls to adjust the usable part of the filter element 5.

[0022] Reference Figure 2The other end of the filter element 5 is fixedly connected to a pull frame 502, which is made of silicone rubber. The staff holds the pull frame 502 and pulls the filter element 5 to reset it.

[0023] The implementation principle of the cell proliferation dynamic monitoring device based on electrical impedance technology in this application embodiment is as follows: First, the cell analysis monitor 4 is connected to the external analysis software host. The cell monitoring sample is placed on the top of the cell analysis monitor 4 inside the limiting frame 3. The cell sample is analyzed and monitored by the instrument. The front half of the filter lens 5 is a fluorescence filter, which can effectively separate the excitation light and emission light, enhance the accuracy and clarity of fluorescence detection, reduce background interference, and make the fluorescence characteristics of the cells more obvious. The rear half of the filter lens 5 is a polarization filter, which can reveal the special optical properties of the cells and provide new dimensions and information. The staff adjusts the position of the filter lens 5 according to the detection requirements of the sample to reduce the limitations of the device. At the same time, the limiting plate 2 is installed on the top of the support rod 7, and the lighting lamp 1 is installed on the top of the limiting frame 3. The magnetic block 801 is adsorbed and connected to the support rod 7. The lighting lamp 1 is an adjustable wavelength light source, which can accurately excite specific fluorescence, improve the specificity and sensitivity of detection, and ensure more accurate acquisition of the fluorescence signal of the cells, thereby performing cell activity, protein expression and other analyses.

[0024] Finally, the following points should be noted: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installation", "connection", and "linkage" should be interpreted broadly, and can be mechanical or electrical connections, or internal connections between two components, or direct connections. "Up", "down", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may change.

[0025] Secondly: The accompanying drawings of the embodiments disclosed in this utility model only involve the structures involved in the embodiments disclosed in this utility model. Other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of this utility model can be combined with each other.

[0026] Finally: The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

[0027] The above are all preferred embodiments of this application, and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A cell proliferation dynamic monitoring device based on electrical impedance technology, comprising an illumination lamp (1), a limiting frame (3), and a cell analysis and monitoring instrument (4), characterized in that: The cell analysis monitor (4) is equipped with a limiting frame (3) on its top. There are three limiting frames (3). Filter lenses (5) are movably installed inside the three limiting frames (3). A support rod (7) is fixedly connected to the top of the cell analysis monitor (4) around the limiting frame (3). A limiting plate (2) is movably installed on the top of the support rod (7). A limiting rod (8) is fixedly connected to the bottom of the limiting plate (2). A magnetic block (801) is fixedly connected to the bottom of the limiting rod (8). A lighting lamp (1) is embedded inside the limiting plate (2).

2. The cell proliferation dynamic monitoring device based on electrical impedance technology according to claim 1, characterized in that: The support rod (7) has a slot (701) inside, and the limiting rod (8) is fitted into the slot (701).

3. The cell proliferation dynamic monitoring device based on electrical impedance technology according to claim 1, characterized in that: One end of the support rod (7) is fixedly connected to the protective shell (6), and the filter (5) penetrates the protective shell (6).

4. The cell proliferation dynamic monitoring device based on electrical impedance technology according to claim 1, characterized in that: One end of the filter element (5) is fixedly connected to a pull block (501), and the pull block (501) is made of aluminum alloy.

5. The cell proliferation dynamic monitoring device based on electrical impedance technology according to claim 1, characterized in that: The other end of the filter element (5) is fixedly connected to a pull frame (502), and the pull frame (502) is made of silicone rubber.

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