Liquid storage bottle constant temperature and ventilation device for measuring lopinavir liquid chromatogram

Abstract

The utility model discloses a liquid storage bottle constant temperature and ventilation device for measuring lopinavir liquid chromatography, which belongs to the technical field of analysis and detection, and comprises a reaction unit, a temperature control unit and an exhaust unit, the reaction unit comprises a reaction box, a storage bottle is arranged in the reaction box, one side of the reaction box is provided with a door, and the other side of the reaction box is provided with an air inlet and an air outlet. The temperature control unit comprises a heating lamp arranged on the inner wall of the reaction box, an adjusting mechanism is arranged on the side face of the heating lamp, a power line penetrating through the reaction box is connected with the heating lamp, and the exhaust unit comprises an air guide pipe arranged at the top of the reaction box and penetrating through the interior of the reaction box. The top of the air guide pipe is provided with an air blowing mechanism, the top of the reaction box and the air guide pipe are provided with an exhaust pipe in a non-contact manner, and the device has the advantages that gas can be conveniently absorbed and subsequently treated, and the environment temperature is kept stable through the temperature control unit, so that the whole detection test is stably carried out.

Description

Technical Field

[0001] This utility model relates to the field of analytical detection technology, specifically to a temperature control and ventilation device for a liquid chromatography reservoir for determining lopinavir. Background Technology

[0002] In existing technologies, liquid chromatographs consist of a mobile phase reservoir, a pump, an autosampler, a column oven, a detector, and a data processing system. However, the mobile phase reservoir is usually exposed to air. When the ambient temperature is unstable or cannot be controlled, it can lead to problems such as poor repeatability of the analytical method and poor separation effect. Moreover, when the concentration of the mobile phase buffer salt is high, a low ambient temperature can cause the buffer salt to precipitate, thereby clogging the filter head and ultimately preventing the detection experiment from continuing.

[0003] Furthermore, the volatile mobile phase is usually dispersed in the air and needs to be absorbed and collected.

[0004] Therefore, it is necessary to propose a method to maintain a stable ambient temperature and reduce temperature differences in order to better conduct experiments. Utility Model Content

[0005] The purpose of this invention is to provide a temperature control and ventilation device for a liquid chromatography storage bottle for determining lopinavir, so as to at least partially solve the above-mentioned technical problems, maintain the stability of the ambient temperature, and reduce temperature differences.

[0006] To achieve the above objectives, this utility model provides the following technical solution: it includes a reaction unit, a temperature control unit, and an exhaust unit. The reaction unit includes a reaction box, and a storage bottle is disposed inside the reaction box. One side of the reaction box is provided with a door for opening and closing.

[0007] The temperature control unit includes a heating lamp disposed on the inner wall of the reaction box, an adjustment mechanism is provided on the side of the heating lamp, and a power cord passing through the reaction box is connected to the heating lamp.

[0008] The exhaust unit includes an air duct disposed on the top of the reaction box and passing through the inside of the reaction box. A blower mechanism is provided on the top of the air duct. An exhaust pipe is disposed on the top of the reaction box without contacting the air duct. A positioning hole is provided on the inner wall of the exhaust pipe. A rotating rod is rotatably installed inside the positioning hole. A baffle is fixedly installed on the end of the rotating rod away from the positioning hole. A U-shaped guide pipe is fixedly connected to the bottom of the air duct and the exhaust pipe. Several air inlets are provided on the U-shaped guide pipe below the exhaust pipe.

[0009] Preferably, the opening of the reaction box can be opened and closed by a rotating door.

[0010] Preferably, several heating lamps are evenly arranged and installed on the inner wall of the reaction box.

[0011] Preferably, the top of the air duct is sealed, and the interior of the air duct is through-hole.

[0012] Preferably, the exhaust pipe and the U-shaped guide pipe are provided with through holes at both ends.

[0013] Preferably, both the baffle and the exhaust pipe are circular, and the inner wall of the baffle has a sealing ring.

[0014] Preferably, the air inlet passes through the U-shaped guide tube, and the air inlet is irregularly arranged on the U-shaped guide tube.

[0015] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0016] In use, this invention heats the heating lamp by energizing the power cord. The heat of the heating lamp is adjusted according to the internal temperature of the reaction chamber via an adjustment mechanism, and different heights of the heating lamps allow for temperature adjustment. Gas in the reaction chamber enters the U-shaped guide tube through the air inlet. A blower blows air into the guide tube, and the air is carried through the U-shaped guide tube to the exhaust pipe, where it is then collected and processed by other collection mechanisms. Due to the negative pressure setting, gas at the air inlet is drawn into the U-shaped guide tube, increasing the gas flow rate and facilitating absorption and subsequent processing. The temperature control unit keeps the ambient temperature stable, ensuring stable testing. Attached Figure Description

[0017] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a front sectional view of the overall structure of this embodiment;

[0019] Figure 2 This is a front sectional view and a rear bottom view of the overall structure of this embodiment;

[0020] Figure 3 This is a side sectional view of the overall structure of this embodiment;

[0021] Figure 4 This is an enlarged schematic diagram of the structure at point A in this embodiment.

[0022] The attached diagram lists the components represented by each number as follows:

[0023] 100. Reaction unit; 110. Reaction box; 120. Storage bottle;

[0024] 200. Temperature control unit; 210. Heating lamp; 211. Adjustment mechanism; 220. Power cord;

[0025] 300, Exhaust unit; 310, Air duct; 320, Blower mechanism; 330, Exhaust pipe; 331, Positioning hole; 3311, Rotating rod; 3312, Baffle; 340, U-shaped guide tube; 341, Air inlet. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0027] Please see Figure 1-4 This utility model provides a technical solution: a constant temperature and ventilation device for a liquid chromatography storage bottle for determining lopinavir, including a reaction unit 100, a temperature control unit 200, and an exhaust unit 300. The reaction unit 100 includes a reaction box 110, the opening of which can be opened and closed by a rotating door. A storage bottle 120 is provided inside the reaction box 110. One side of the reaction box 110 is provided with a door for opening and closing. The storage bottle 120 can be placed inside the reaction box 110, and the pipes can be extended out of the reaction box 110 for experiments. The overall experiment is confined to a certain space to prevent it from being greatly affected. The side of the reaction box 110 can be opened and closed to perform operations such as sealing or opening for observation.

[0028] See Figure 1 and Figure 2 In a preferred embodiment, the temperature control unit 200 includes heating lamps 210 disposed on the inner wall of the reaction box 110. An adjustment mechanism 211 is provided on the side of the heating lamps 210. A power cord 220 is connected to the heating lamps 210 and passes through the reaction box 110. Several heating lamps 210 are evenly arranged on the inner wall of the reaction box 110. The heating lamps 210 are heated by powering on the power cord 220. The heat of the heating lamps 210 is adjusted by the adjustment mechanism 211 according to the internal temperature of the reaction box 110. Different height temperature adjustments can be selected by heating lamps 210 at different heights. The multiple heating lamps 210 can maintain a sufficiently stable internal temperature of the reaction box 110 and prevent large temperature differences or excessively low temperatures.

[0029] See Figure 2 , Figure 3 and Figure 4 In a further preferred embodiment, the exhaust unit 300 includes an air duct 310 disposed on the top of the reaction box 110 and passing through the interior of the reaction box 110. The interior of the air duct 310 is provided with a through hole, and the top of the air duct 310 is provided with a blower mechanism 320. The blower mechanism 320 can blow the gas inside the air duct 310 to the exhaust pipe. The top of the air duct 310 is sealed to prevent gas from being discharged from the top.

[0030] See Figure 2 , Figure 3 and Figure 4 In a further preferred embodiment, the gas can only be discharged from the exhaust pipe. An exhaust pipe 330 is provided on the top of the reaction box 110 without contacting the air duct 310. A positioning hole 331 is provided on the inner wall of the exhaust pipe 330. A rotating rod 3311 is rotatably installed inside the positioning hole 331. A baffle 3312 is fixedly installed at the end of the rotating rod 3311 away from the positioning hole 331. Both the baffle 3312 and the exhaust pipe 330 are circular. A sealing ring is provided on the inner wall of the baffle 3312. When venting is not required, the baffle 3312 is kept parallel to the inside of the exhaust pipe 330, and the gas cannot be leaked by the sealing ring. When venting is required, pressure is applied to the baffle 3312, causing the rotating rod 3311 to rotate and keeping the baffle 3312 vertical, which opens the exhaust pipe 330 and allows the gas to be discharged.

[0031] A U-shaped guide tube 340 is fixedly connected to the bottom of the air duct 310 and the exhaust pipe 330. The exhaust pipe 330 and the U-shaped guide tube 340 are provided with through holes at both ends. The flow of gas in the air duct 310 can be guided to the exhaust pipe 330 and discharged through the U-shaped guide tube 340. Several air inlets 341 are opened in the lower part of the U-shaped guide tube 340. The air inlets 341 pass through the U-shaped guide tube 340 and are irregularly arranged on the U-shaped guide tube 340. Since the temperature inside the reaction box 110 is kept stable, the gas molecules remain active and can move upward and be discharged through the several air inlets 341.

[0032] In the description of this utility model, it should be understood that the terms "coaxial", "bottom", "one end", "top", "middle", "other end", "upper", "side", "top", "inner", "front", "center", "both ends", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0033] In this utility model, unless otherwise explicitly specified and limited, the terms "installation", "setting", "connection", "fixing", "screw connection", etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components or the interaction between two components. Unless otherwise explicitly limited, those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0034] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A temperature control and ventilation device for a liquid chromatography reservoir for determining lopinavir, comprising a reaction unit (100), a temperature control unit (200), and an exhaust unit (300), characterized in that: The reaction unit (100) includes a reaction box (110), inside which a storage bottle (120) is provided, and one side of the reaction box (110) is provided with a door for opening and closing; The temperature control unit (200) includes a heating lamp (210) disposed on the inner wall of the reaction box (110), and an adjustment mechanism (211) is provided on the side of the heating lamp (210). A power cord (220) passing through the reaction box (110) is connected to the heating lamp (210). The exhaust unit (300) includes a duct (310) disposed on the top of the reaction box (110) and passing through the interior of the reaction box (110). A blower mechanism (320) is provided on the top of the duct (310). An exhaust pipe (330) is provided on the top of the reaction box (110) without contacting the duct (310). A positioning hole (331) is provided on the inner wall of the exhaust pipe (330). A rotating rod (3311) is rotatably installed inside the positioning hole (331). A baffle (3312) is fixedly installed at the end of the rotating rod (3311) away from the positioning hole (331). A U-shaped guide pipe (340) is fixedly connected to the bottom of the duct (310) and the exhaust pipe (330). A plurality of air inlets (341) are provided on the U-shaped guide pipe (340) below the exhaust pipe (330).

2. The temperature control and ventilation device for a liquid chromatography reservoir for determining lopinavir according to claim 1, characterized in that: The opening of the reaction box (110) can be opened and closed by rotating a door.

3. The temperature control and ventilation device for a liquid chromatography reservoir for determining lopinavir according to claim 1, characterized in that: Several heating lamps (210) are evenly arranged and installed on the inner wall of the reaction box (110).

4. The temperature control and ventilation device for a liquid chromatography reservoir for determining lopinavir according to claim 1, characterized in that: The top of the air duct (310) is sealed, and the interior of the air duct (310) is through-hole.

5. The temperature control and ventilation device for a liquid chromatography reservoir for determining lopinavir according to claim 1, characterized in that: The exhaust pipe (330) and the U-shaped guide pipe (340) are provided with through holes at both ends.

6. The temperature control and ventilation device for a liquid chromatography reservoir for determining lopinavir according to claim 1, characterized in that: Both the baffle (3312) and the exhaust pipe (330) are circular, and the inner wall of the baffle (3312) is provided with a sealing ring.

7. The temperature control and ventilation device for a liquid chromatography reservoir for determining lopinavir according to claim 5, characterized in that: The air inlet (341) passes through the U-shaped guide tube (340), and the air inlet (341) is irregularly arranged on the U-shaped guide tube (340).

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