Connecting assembly applied to solid-phase extraction

Abstract

The utility model relates to a connecting assembly applied to solid-phase extraction. The connecting assembly comprises a sealing plate and an adapter, the sealing plate comprises a silica gel pad and a fixing frame arranged on the edge of the silica gel pad in a surrounding mode, and a plurality of first connecting structures are arranged on the silica gel pad. The first connecting structure comprises a first connecting end, a hollow channel and a second connecting end, and the second connecting end is used for being inserted into and hermetically connected with the solid-phase extraction column. The adapter is detachably connected with the pipettor, a plurality of second connecting structures are arranged on the adapter, the number and the position of the second connecting structures correspond to those of the first connecting structures, each second connecting structure comprises a connecting piece and an avoiding hole, and the connecting pieces are connected with the first connecting ends in a sleeving interference fit mode; a pipette passes through the avoiding hole and is inserted into the hollow channel. Compared with the prior art, the connecting assembly is used for connecting the pipettor and the sealing plate, the instrument can synchronously move the sealing plate by moving the pipettor, and the treatment efficiency of an experiment is improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to chemical analysis instrument field especially is applied to the connecting assembly for solid phase extraction. BACKGROUND

[0002] Solid phase extraction is a kind of sample pretreatment technology developed in recent years, which is developed by combining liquid-solid extraction and column liquid chromatography technology, and is mainly used for the separation, purification and concentration of sample, compared with traditional liquid-liquid extraction method, can improve the recovery rate of analyte, more effectively separate analyte and interfering component, reduce sample pretreatment process, simple operation, time-saving and labor-saving. It is widely used in medicine, food, environment, commercial inspection, chemical industry and other fields.

[0003] In the current automatic instrument, the sealing plate of solid phase extraction needs to be separately transported by a gripper module, which leads to low overall processing efficiency and difficulty in further simplifying the system. SUMMARY

[0004] In view of the above technical problems, the utility model provides a connecting assembly applied to solid phase extraction, the connecting assembly is used for connecting a liquid transfer device and a sealing plate, and the instrument can move the sealing plate synchronously by moving the liquid transfer device, thereby improving the processing efficiency of the experiment.

[0005] To achieve the above object, the utility model adopts the following technical scheme:

[0006] A connecting assembly applied to solid phase extraction, comprising a sealing plate and an adapter;

[0007] The sealing plate comprises a silica gel pad and a fixed frame surrounding the edge of the silica gel pad, and a plurality of first connecting structures are arranged on the silica gel pad;

[0008] The first connecting structure comprises a first connecting end, a hollow channel and a second connecting end arranged vertically in sequence, the first connecting end is protrudingly arranged on the top of the silica gel pad, the hollow channel connects the first connecting end and the second connecting end, and the second connecting end is protrudingly arranged on the bottom of the silica gel pad, wherein the second connecting end is used for inserting and sealingly connecting a solid phase extraction column;

[0009] The adapter is detachably connected with the liquid transfer device, a plurality of second connecting structures are arranged on the adapter, the number and position of the second connecting structures correspond to the first connecting structures, the second connecting structure comprises a connecting piece and a relief hole, the connecting piece is connected with the first connecting end in interference fit, and the relief hole is used for passing through the liquid transfer gun and inserting into the hollow channel.

[0010] In one of the embodiments, the connecting piece is arranged on the outer edge of the first connecting end.

[0011] In one of the embodiments, the connecting piece is in a columnar shape, the avoiding hole is arranged inside the connecting piece, the first connecting end is internally provided with a positioning groove for inserting and positioning the end of the connecting piece, and the positioning groove is arranged in an interference fit with the outer edge of the connecting piece.

[0012] In one of the embodiments, the bottom of the connecting piece is provided with a guide bevel.

[0013] In one of the embodiments, a threaded hole is formed in the adapter, and the adapter is detachably connected with the pipette through a bolt.

[0014] In one of the embodiments, the fixing frame comprises two frames, and the two frames are clamped on the upper and lower sides of the silica gel pad.

[0015] The utility model has the following advantages due to the above technical scheme:

[0016] When using the connecting assembly, the adapter needs to be first installed on the pipette, and the pipette gun is correspondingly inserted into the avoiding hole. During use, the sealing plate is integrally installed on the adapter. During installation, the first connecting end is correspondingly sleeved with the connecting piece on the adapter, and the two are connected in an interference fit. Therefore, the 96 first connecting structures are correspondingly sleeved with the 96 second connecting structures in an interference fit, and the pipette gun is correspondingly inserted into the hollow channel. After the installation of the sealing plate is completed, the pipette can be normally used. When the pipette is moved under the control of the system, the sealing plate will be moved synchronously. When extraction is performed, the pipette is moved to above the solid-phase extraction column under the control of the pipette, and the pipette gun is inserted into the extraction column under the continuous control. At this time, the second connecting end of the sealing plate is inserted into the extraction column, the outer edge of the second connecting end is sealingly connected with the solid-phase extraction column, the sealing effect is achieved, and liquid can be added for subsequent extraction process operation. Compared with the prior art, the connecting assembly is used for connecting the pipette and the sealing plate. The instrument can move the sealing plate synchronously by moving the pipette, and the processing efficiency of the experiment is improved. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 FIG. 1 is a specific structural schematic view of the sealing plate in one embodiment of the utility model;

[0018] Figure 2 FIG. 2 is a specific structural schematic view of the connecting assembly in one embodiment of the utility model;

[0019] Figure 3 FIG. 3 is a specific structural schematic view of the connecting assembly in another embodiment of the utility model;

[0020] REFERENCE SIGNS:

[0021] 1, sealing plate; 11, silica gel pad; 111, first connecting structure; 1111, first connecting end; 1112, second connecting end; 1113, hollow channel; 1114, positioning groove; 12, fixed frame; 121, frame;

[0022] 2, adapter; 21, second connecting structure; 211, connecting piece; 212, avoiding hole; 213, guide bevel; 22, threaded hole. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical scheme and advantages of the utility model more clear, the technical scheme in the utility model is described clearly and completely below. Obviously, the described embodiments are part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by the person skilled in the art without creative labor belong to the protection scope of the utility model.

[0024] Unless otherwise defined, the technical terms or scientific terms used in the utility model should be understood as the usual meaning by the person skilled in the art in the field to which the utility model belongs. The "first", "second", "third", "fourth" and similar words used in the utility model do not represent any order, quantity or importance, but are only used to distinguish different components. "Include" or "contain" and similar words mean that the elements or objects before the word cover the elements or objects listed after the word and their equivalents, without excluding other elements or objects. "Connection" or "connection" and similar words are not limited to physical or mechanical connection, but can include electrical connection, whether direct or indirect.

[0025] Solid phase extraction is a sample pretreatment technology developed in recent years, which is developed by combining liquid-solid extraction and column liquid chromatography technology, and is mainly used for sample separation, purification and concentration. Compared with the traditional liquid-liquid extraction method, the recovery rate of the analyte can be improved, the analyte and interfering components can be separated more effectively, the sample pretreatment process can be reduced, and the operation is simple, time-saving and labor-saving. It is widely used in medicine, food, environment, commercial inspection, chemical industry and other fields.

[0026] In the current automatic instrument, the sealing plate of solid phase extraction needs to be separately transported by the gripper module, which leads to low overall processing efficiency and difficulty in further simplifying the system. In view of the above technical problems, the utility model provides a connecting assembly applied to solid phase extraction, which is used for connecting a pipettor and a sealing plate. The instrument can move the sealing plate synchronously by moving the pipettor, thereby improving the processing efficiency of the experiment. The technical scheme of the utility model will be described in detail below in combination with specific examples.

[0027] REFERENCE Figure 1and Figure 2 As shown in the utility model relates to a kind of connection assembly applied to solid phase extraction, including sealing plate 1 and adapter 2. Among them, sealing plate 1 includes silica gel pad 11 and the fixed frame 12 surrounded in the edge of silica gel pad 11, a plurality of first connection structures 111 are provided on silica gel pad 11.

[0028] First connection structure 111 includes vertically arranged first connecting end 1111, hollow passage 1113 and second connecting end 1112, first connecting end 1111 is protrudingly arranged at the top of silica gel pad 11, hollow passage 1113 connects first connecting end 1111 with second connecting end 1112, and second connecting end 1112 is protrudingly arranged at the bottom of silica gel pad 11, wherein, second connecting end 1112 is used to insert sealing connection solid phase extraction column.

[0029] Adapter 2 is detachably connected with pipette, and a plurality of second connection structures 21 are provided on adapter 2, the number and position of the second connection structures 21 correspond to the first connection structures 111, the second connection structures 21 include connectors 211 and avoiding holes 212, the connectors 211 are connected with the first connecting ends 1111 in interference fit, and the avoiding holes 212 are used for the pipette gun to pass through and insert into the hollow passages 1113.

[0030] It should be noted that the design and manufacture of the first connection structure 111 and the second connection structure 21 are related to the number of channels, and in this embodiment, the pipette is a 96-channel pipette, so the first connection structure 111 and the second connection structure 21 correspond to the 96-channel pipette.

[0031] Exemplarily, when using the connection assembly, the adapter 2 needs to be installed on the pipette first, and the pipette gun is inserted into the avoiding hole 212 correspondingly, and during use, the sealing plate 1 is installed on the adapter 2 as a whole, and during installation, the first connecting end 1111 is correspondingly fitted with the connector 211 on the adapter 2, and the two are connected in interference fit, so the 96 first connection structures 111 are fitted with the 96 second connection structures 21 in interference fit, and the pipette gun is correspondingly inserted into the hollow passage 1113. After the installation of the sealing plate 1 is completed, the pipette can be used normally, and the system controls the pipette to move, which will drive the sealing plate 1 to move synchronously. When performing extraction operation, the pipette is controlled to move above the solid phase extraction column, and then the pipette gun is inserted into the extraction column, at which time the second connecting end 1112 of the sealing plate 1 is inserted into the extraction column, and the outer edge of the second connecting end 1112 is sealingly connected with the solid phase extraction column, achieving sealing effect. Subsequently, liquid can be added to perform subsequent extraction process operation. Compared with the prior art, the connection assembly is used to connect the pipette and the sealing plate 1, and the instrument can move the sealing plate 1 synchronously by moving the pipette, improving the processing efficiency of the experiment.

[0032] Referring to Figure 1 And Figure 2 As shown in the figure, in an embodiment, the connection structure of the connecting piece 211 and the first connecting end 1111 is further refined, the second connecting structure 21 is provided in a whole barrel shape, and the connecting piece 211 is sleeved on the outer edge of the first connecting end 1111.

[0033] Specifically, a threaded hole 22 is formed on the adapter 2, and the adapter 2 is detachably connected with the pipette through a bolt.

[0034] In this embodiment, the fixing frame 12 includes two frames 121, which are clamped on the upper and lower sides of the silica gel pad 11.

[0035] Referring to Figure 3 As shown in the figure, in another embodiment, the connection structure of the connecting piece 211 and the first connecting end 1111 is further refined, the second connecting structure 21 is provided in a whole column shape, the connecting piece 211 is provided in a column shape, the avoiding hole 212 is provided inside the connecting piece 211, the first connecting end 1111 is provided with a positioning groove 1114 for inserting and positioning the end of the connecting piece 211, and the positioning groove 1114 is provided in an interference fit with the outer edge of the connecting piece 211.

[0036] In this embodiment, more preferably, in order to facilitate the insertion of the connecting piece 211 into the positioning groove 1114, a guide inclined angle 213 is provided at the bottom of the connecting piece 211.

[0037] Finally, it should be noted that: the above examples are only used to illustrate the technical solutions of the present application, and not to limit them; although the present application has been described in detail with reference to the foregoing examples, those skilled in the art should understand that: it can still modify the technical solutions recorded in the foregoing examples, or make equivalent replacement for part of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present application.

Claims

1. A connection assembly for use in solid phase extraction, characterized in that The sealing plate and the adapter are included. The sealing plate includes a silica gel pad and a fixed frame surrounding the edge of the silica gel pad, and a plurality of first connecting structures are arranged on the silica gel pad. The first connecting structure includes a first connecting end, a hollow channel and a second connecting end arranged vertically in sequence, the first connecting end is protrudingly arranged on the top of the silica gel pad, the hollow channel connects the first connecting end and the second connecting end, and the second connecting end is protrudingly arranged on the bottom of the silica gel pad, wherein the second connecting end is used for inserting a sealed solid-phase extraction column. The adapter is detachably connected with a pipette, a plurality of second connecting structures are arranged on the adapter, the number and position of the second connecting structures correspond to the first connecting structures, the second connecting structure includes a connecting piece and a avoiding hole, the connecting piece is connected with the first connecting end in interference fit, and the avoiding hole is used for the pipette gun to pass through and insert into the hollow channel.

2. The connection assembly of claim 1, wherein, The connecting piece is sleeved on the outer edge of the first connecting end.

3. The connection assembly of claim 1, wherein, The connecting piece is cylindrically arranged, the avoiding hole is arranged in the interior of the connecting piece, the first connecting end is internally provided with a positioning groove for inserting and positioning the end of the connecting piece, and the positioning groove is arranged in interference fit with the outer edge of the connecting piece.

4. The connection assembly of claim 3, wherein, The bottom of the connecting piece is provided with a guide bevel.

5. The connection assembly of claim 1, wherein, The adapter is provided with a threaded hole, and the adapter is detachably connected with the pipette through bolts.

6. The connection assembly of claim 1, wherein, The fixed frame includes two frames, and the two frames are clamped on the upper and lower sides of the silica gel pad.

Images