Mabazavir granulating equipment

Abstract

The utility model discloses macloxvir granulating equipment, which comprises a power box, a tank body, a cover body, a side driving box, a control unit and a discharge port, an output shaft is arranged at the bottom end in the tank body, a lower connector is arranged at the bottom end of the output shaft, a stirring paddle is arranged on the surface of the lower connector, an engaging strip is arranged on the edge of the stirring paddle, and the engaging strip is connected with the side driving box. The meshing strip is in an upward protruding shape, an upper connector is arranged at the top of the output shaft, and the upper connector and a connecting base are installed. Through the design of the scraping strip, the stirring paddle can be directly assembled with the scraping strip after being disassembled based on the conversion of the use purpose of the stirring paddle, the scraping strip can scrape residues on the inner wall of the tank body, manual repeated scrubbing is not needed, and meanwhile, the suspended stirring paddle can also be used in a relatively high rotating speed process; and the stirring paddle can be continuously cleaned in cooperation with cleaning liquid sprayed from the top, so that the interior of the tank body has a self-cleaning effect, manual wiping and dismounting of the stirring paddle are not needed, and the working efficiency in the cleaning process is improved.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical granulation, and in particular to a granulation device for mabaloxavir. Background Technology

[0002] Due to its inherent properties, mabaloxavir is typically produced using a high-speed mixing granulator. The process involves adding mabaloxavir raw materials, excipients, and binders into a container, where the mixture is rapidly mixed and granulated under the action of a high-speed rotating agitator through stirring, shearing, and compaction. The agitator paddle performs both dry and wet mixing of the materials, while the intersection area at the granulation blades thoroughly breaks down the turbulent material clumps into particles, causing the materials to undergo three-dimensional motion. Through collision, friction, and shearing, the particles ultimately form stable spherical granules.

[0003] However, after mixing, due to the different manufacturing processes of various drug granules, if there are drug residues inside the container, it is necessary to manually remove the internal stirring paddle and cutting blade for cleaning, and thoroughly clean the residues on the inner wall of the container. This is not only time-consuming and laborious, but also results in cleaning residues. In addition, some containers have a structure that is narrow at the top and wide at the bottom, making it difficult to remove the stirring paddle.

[0004] Therefore, in order to address the above problems, a mabaloxavir granulation device is provided here. Utility Model Content

[0005] The technical problem to be solved by this utility model is to overcome the defects of the prior art and provide a mabaloxavir granulation equipment, which mainly solves the problem that the inside of the container is not easy to clean after the existing technology is stirred.

[0006] To solve the above-mentioned technical problems, this utility model provides the following technical solution:

[0007] This utility model relates to a mabaloxavir granulation device, comprising a power box, a tank, a cover, a side drive box, a control unit, and a discharge port. An output shaft is installed at the bottom of the tank, and a lower connector is installed at the bottom of the output shaft. A stirring paddle is provided on the surface of the lower connector, and an engagement strip is provided on the edge of the stirring paddle. The engagement strip is an upward-protruding shape. An upper connector is provided at the top of the output shaft for installation with a connecting seat. The cutting blade and the side drive box are detachably connected. A fastener is installed on the bottom edge of the cover, which is used to elastically snap onto the inner wall of the mounting ring. A raised ring is provided on the inner wall of the tank, and an mounting ring is installed on the upper part of the tank. A scraper is installed at the bottom of the mounting ring. The raised ring and the scraper are embedded. An engagement groove is provided at the bottom of the scraper, and the engagement groove and the engagement strip are arranged vertically.

[0008] Preferably, the upper connector and the output shaft are detachably connected, and the buckle and the cover are threadedly connected.

[0009] Preferably, the scraping strip is attached to the inner wall of the tank body, and the inner wall of the mounting ring is provided with a connecting hole.

[0010] Preferably, the scraping strip comprises a curved portion and a vertical portion, and the outer surface of the curved portion is provided with a sliding groove, and the sliding groove and the protruding ring are slidingly buckled.

[0011] Preferably, the bottom end of the upper connecting head is provided with a mounting thread for fixed connection with the connecting seat.

[0012] Preferably, the inside of the power box comprises a driving motor and a speed reducer, the driving motor is used for transmission to the output shaft, and the connecting position of the cutting knife and the side driving box is located in the middle of the thickness of the tank body.

[0013] Preferably, the inner side edge of the curved portion is provided with a streamline curve, the vertical portion and the curved portion are in arc shape, and the number of the curved portions is not less than four.

[0014] Compared with the prior art, the utility model has the beneficial effects as follows:

[0015] The utility model discloses a scraping strip is designed, based on the use purpose of change stirring paddle, let stirring paddle can be directly assembled with scraping strip after dismounting, let scraping strip can scrape the residual of tank body inner wall, need not manual repeated scrubbing, and the suspended stirring paddle can also be cleaned in the faster speed flow process, and can also cooperate with the cleaning fluid of top spraying and clean itself constantly, so that the tank body inside produces the self -cleaning effect, need not manual wiping and dismounting stirring paddle, improve the work efficiency in the cleaning process. BRIEF DESCRIPTION OF DRAWINGS

[0016] The drawings are used to provide further understanding of the utility model and constitute a part of the specification, are used to explain the utility model together with the embodiments of the utility model, and do not constitute the limitation to the utility model.

[0017] Figure 1 It is the overall structure schematic diagram of the utility model;

[0018] Figure 2 It is the tank body structure section view of the utility model;

[0019] Figure 3 It is the cover structure schematic diagram of the utility model;

[0020] Figure 4 It is the tank body structure plan view of the utility model;

[0021] Figure 5 It is the scraping strip structure schematic diagram of the utility model;

[0022] Figure 6 It is the meshing groove structure front view of the utility model;

[0023] In the diagram: 1. Power box; 101. Tank body; 102. Cover; 103. Side drive box; 104. Control unit; 105. Discharge port; 106. Buckle block; 107. Raised ring; 2. Output shaft; 201. Connecting seat; 202. Lower connector; 203. Upper connector; 204. Mounting thread; 205. Agitator; 206. Engaging bar; 3. Cutting blade; 4. Mounting ring; 401. Scraper; 402. Bending part; 403. Vertical part; 404. Slide groove; 5. Engaging groove; 6. Connecting hole. Detailed Implementation

[0024] The preferred embodiments of the present invention will be described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are for illustration and explanation only and are not intended to limit the present invention.

[0025] In the attached diagram, all identical reference numerals refer to the same components.

[0026] Example 1

[0027] like Figures 1-6 As shown, this utility model provides a mabaloxavir granulation device, including a power box 1, a tank 101, a cover 102, a side drive box 103, a control unit 104, and a discharge port 105. The raw material enters the tank 101 from the surface of the cover 102. The stirring paddle 205 and the cutting blade 3 inside the tank 101 are used to process the raw material into granular drug, which is then discharged from the discharge port 105.

[0028] An output shaft 2 is installed at the bottom of the tank body 101. A lower connector 202 is installed at the bottom of the output shaft 2. An agitator 205 is provided on the surface of the lower connector 202. An engagement strip 206 is provided on the edge of the agitator 205. The engagement strip 206 is upwardly protruding. An upper connector 203 is provided at the top of the output shaft 2. The upper connector 203 is used to install with the connecting seat 201. The cutting blade 3 and the side drive box 103 are detachably connected. A fastener 106 is installed on the bottom edge of the cover 102. The fastener 106 is used to elastically fasten to the inner wall of the mounting ring 4. A raised ring is provided on the inner wall of the tank body 101. 107. An installation ring 4 is installed on the upper part of the tank 101, and a scraper 401 is installed on the bottom of the installation ring 4. The raised ring 107 and the scraper 401 are embedded. The bottom of the scraper 401 is provided with an engagement groove 5. The engagement groove 5 and the engagement bar 206 are arranged vertically. When the inside needs to be cleaned, the cutting blade 3 can be removed and the connecting seat 201 can be removed from the lower connecting head 202 and installed on the upper connecting head 203. The engagement bar 206 can be embedded in the engagement groove 5, so that the stirring paddle 205 can drive the scraper 401 in the middle to scrape off the drug raw materials adhering to the inner wall of the tank 101.

[0029] Further, the upper connector 203 and the output shaft 2 are detachably connected, and the buckle block 106 and the cover 102 are threadedly connected; so that the connecting seat 201 can be directly taken out from the surface of the output shaft 2 after the connector is disassembled.

[0030] Further, the scraping strip 401 is attached to the inner wall of the tank body 101, and the inner wall of the mounting ring 4 is provided with a connecting hole 6; so that after the cover 102 is closed, the buckle block 106 can be buckled into the connecting hole 6, so that the mounting ring 4 and the scraping strip 401 are fixed to the inner wall of the tank body 101.

[0031] Further, the scraping strip 401 includes a curved portion 402 and a vertical portion 403, the outer surface of the curved portion 402 is provided with a sliding groove 404, and the sliding groove 404 and the raised ring 107 are slidingly buckled; so that when the scraping strip 401 rotates, the sliding groove 404 can slide on the surface of the raised ring 107, thereby forming an internal upper and lower limiting effect.

[0032] Further, the bottom end of the upper connector 203 is provided with a mounting thread 204, and the mounting thread 204 is used for fixed connection with the connecting seat 201; so that the connecting seat 201 after disassembly can be fixed at the upper connector 203 through the mounting thread 204.

[0033] Further, the power box 1 includes a driving motor and a speed reducer inside, the driving motor is used for transmission to the output shaft 2, and the connection between the cutting knife 3 and the side drive box 103 is located in the middle of the thickness of the tank body 101; so that the rotating speed output by the driving motor can be adjusted by the speed reducer, which is used to distinguish the granulation state and the cleaning state inside the tank body 101.

[0034] Specifically, in the conventional process, the staff only operates the driving motor inside the power box 1 and the side drive box 103 based on the control unit 104, so that the stirring paddle 205 and the cutting knife 3 in the tank body 101 move, so that the raw materials in the tank body 101 are stirred until they form granules;

[0035] And after the stirring is completed, the inside of the tank 101 is easy to produce residues, at this time the cutting knife 3 and the side drive box 103 can be directly disassembled, and after the connecting seat 201 is disassembled from the lower connecting head 202, the connecting seat 201 is installed to the upper connecting head 203, and at the same time, the engagement strip 206 at the edge of the stirring paddle 205 is inserted into the engagement groove 5 at the bottom of the scraping strip 401, until it enters the middle side of the vertical part 403, forming a frictional fixing, after the buckle 106 of the cover body 102 is disassembled, the cover body 102 is closed; the staff can operate the control unit 104 again to adjust the output power of the driving motor, so that the suspended stirring paddle 205 drives the scraping strip 401 to scrape on the inner wall of the tank 101, and after the limiting and disassembling of the buckle 106, the installation ring 4 can freely rotate, and the sliding groove 404 of the scraping strip 401 can also slide on the surface of the raised ring 107, so that the scraping strip 401 can repeatedly scrape on the inner wall of the tank 101, and if the top is matched with the spraying of cleaning liquid, the stirring paddle 205 and the inner wall of the tank 101 can automatically complete the cleaning work, so that manual cleaning is not required, and the stirring paddle 205 does not need to be disassembled from the inside of the tank 101, thereby increasing the overall cleaning efficiency and reducing the burden of manual work.

[0036] Embodiment 2

[0037] The difference from Embodiment 1 is that, as shown in the figure, the inner side edge of the curved part 402 is provided with a streamline curve, the vertical part 403 and the curved part 402 are arc-shaped, and the number of the curved part 402 is not less than four. Figure 5

[0038] Specifically, when the number of the vertical part 403 and the curved part 402 is large, after the internal stirring paddle 205 stirs, the raw materials can continuously flow upwards along the inner wall of the tank 101 based on the channel of the vertical part 403 and the streamline structure of the curved part 402, so as to form a central curved flow cycle when colliding with the inner wall of the tank 101, thereby reducing the direct collision with the inner wall, thereby increasing the internal flow rate and improving the flow in the tank 101.

[0039] Finally, it should be noted that: the above only describes the preferred embodiments of the present application, and is not used to limit the present application, although the present application has been described in detail with reference to the foregoing embodiments, and for those skilled in the art, the technical solutions recorded in the foregoing embodiments can be modified, or some technical features can be replaced. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.​

Claims

1. A maraviroc granulation device, comprising a power box (1), a tank body (101), a cover body (102), a side drive box (103), a control unit (104) and a discharge port (105), characterized in that, The bottom of the tank body (101) is provided with an output shaft (2), the bottom of the output shaft (2) is provided with a lower connector (202), the surface of the lower connector (202) is provided with a stirring paddle (205), the edge of the stirring paddle (205) is provided with an engaging strip (206), the engaging strip (206) is an upward protrusion, the top of the output shaft (2) is provided with an upper connector (203), the upper connector (203) is used for being connected with a connecting seat (201), a cutting knife (3) and a side drive box (103) are detachably connected, the bottom edge of the cover body (102) is provided with a buckle block (106), the buckle block (106) is used for being elastically buckled to the inner wall of a mounting ring (4), the inner wall of the tank body (101) is provided with a protruding ring (107), the upper portion of the tank body (101) is provided with the mounting ring (4), the bottom of the mounting ring (4) is provided with a scraping strip (401), the protruding ring (107) and the scraping strip (401) are embeddedly arranged, the bottom of the scraping strip (401) is provided with an engaging groove (5), and the engaging groove (5) and the engaging strip (206) are arranged in an up-down corresponding mode.

2. A maraviroc granulating apparatus according to claim 1, wherein, The upper connector (203) and the output shaft (2) are detachably connected, and the buckle block (106) and the cover body (102) are screw-connected.

3. A maraviroc granulating apparatus according to claim 1, wherein The scraping strip (401) is attached to the inner wall of the tank body (101), and the inner wall of the mounting ring (4) is provided with a connecting hole (6).

4. A maraviroc granulating apparatus according to claim 1, wherein The scraping strip (401) comprises a curved portion (402) and a vertical portion (403), the outer surface of the curved portion (402) is provided with a sliding groove (404), and the sliding groove (404) and the protruding ring (107) are slidably buckled.

5. A maraviroc granulating apparatus according to claim 1, wherein The bottom of the upper connector (203) is provided with a mounting thread (204), and the mounting thread (204) is used for being fixedly connected with the connecting seat (201).

6. A maraviroc granulating apparatus according to claim 1, wherein The power box (1) comprises a driving motor and a speed reducer in the inside, the driving motor is used for being transmitted to the output shaft (2), and the connecting position of the cutting knife (3) and the side drive box (103) is located in the middle of the thickness of the tank body (101).

7. A maraviroc granulating apparatus according to claim 4, wherein The inner side edge of the curved portion (402) is provided with a streamline curve, the vertical portion (403) and the curved portion (402) are in an arc shape, and the number of the curved portions (402) is not less than four.

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