Pathological tissue wax block pretreatment device

By designing a pathological tissue paraffin block pretreatment device, which uses a vertical channel and a wedge-shaped dewaxing device to automatically clean the edges of the paraffin blocks, the problem of low efficiency and high labor intensity in traditional trimming operations has been solved, achieving efficient and accurate paraffin block trimming and sectioning.

CN223955257UActive Publication Date: 2026-02-27SUN YAT SEN UNIVERSITY CANCER CENTER (CANCER HOSPITAL AFFILIATED TO SUN YAT SEN UNIVERSITY CANCER RESEARCH INSTITUTE OF SUN YAT SEN UNIVERSITY)
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Patent Information

Application Number
CN202520496828.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-20
Publication Date
2026-02-27
Estimated Expiration
2035-03-20

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Abstract

The utility model discloses a pathological tissue wax block pretreatment device. The pathological tissue wax block pretreatment device comprises a vertical channel, a wedge-shaped surface treatment device and a heating assembly, the vertical channel is provided with a wax block inlet and a wax block outlet, the wax block inlet is formed in the top end of the vertical channel, the wax block outlet is formed in the side wall of the vertical channel, and the sectional area of the vertical channel is gradually reduced from the wax block inlet to the wax block outlet; the tray is arranged at the wax block outlet and comprises a bottom plate, a connecting plate and a top plate, the bottom plate, the connecting plate and the top plate all extend in the horizontal direction, the bottom plate is fixedly connected with the connecting plate, and the top plate is rotatably connected to the connecting plate and used for being attached to the wedge-shaped face of the pathological tissue wax block; and the heating assembly is used for heating the vertical channel and the top plate and the bottom plate of the wedge-shaped surface wax removal device. According to the device, the top plate can be attached to the wedge-shaped face of the pathological tissue wax block in a self-adaptive mode. Under the action of the heating assembly, redundant wax blocks on the wedge-shaped face and the bottom face of the pathological tissue wax block are melted, and therefore information on the wedge-shaped face can be clearly displayed.
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Description

TECHNICAL FIELD

[0001] The utility model relates to clinical human body and animal and plant biological tissue section inspection field especially relates to pathological tissue wax block pretreatment device. BACKGROUND

[0002] Pathological tissue wax block is constituted by embedding box and wax block ontology containing tissue sample, the edge of embedding box often forms protrusion because of paraffin overflow in traditional craft, need additional use waxing instrument or cutter trimming before section, this edge trimming operation not only increases medical staff labor intensity, also reduces work efficiency. SUMMARY

[0003] The utility model discloses at least one of the technical problems existing in the prior art is solved. To this end, one purpose of the utility model is to provide a pathological tissue wax block pretreatment device, which can reduce the labor intensity of medical staff and improve work efficiency.

[0004] The embodiment provides a pathological tissue wax block pretreatment device, which comprises: a vertical channel having a wax block inlet and a wax block outlet, the wax block inlet is arranged at the top end of the vertical channel, and the wax block outlet is arranged on the side wall of the vertical channel, and the cross-sectional area of the vertical channel gradually decreases from the wax block inlet to the wax block outlet; a wedge face wax removing device is arranged at the wax block outlet and comprises a bottom plate, a connecting plate and a top plate, the bottom plate, the connecting plate and the top plate all extend along the horizontal direction, the bottom plate is fixedly connected with the connecting plate, and the top plate is rotatably connected with the connecting plate and used for abutting the wedge face of the pathological tissue wax block; and a heating assembly is used for heating the vertical channel, the top plate and the bottom plate of the wedge face wax removing device.

[0005] In some embodiments, the bottom plate, the connecting plate and the top plate surround a U-shaped channel, and the opening of the U-shaped channel is provided with a stop edge on both sides.

[0006] In some embodiments, the wedge face wax removing device comprises an elastic hinge; the top plate and the connecting plate are connected through the elastic hinge, and the elastic hinge is used for applying an elastic force to the top plate to make the top plate have a tendency to rotate towards the connecting plate.

[0007] In some embodiments, the side walls on the opposite sides of the vertical channel are respectively provided with the wax block outlet and an inspection opening, and the inspection opening is aligned with the wax block outlet in the horizontal direction.

[0008] In some embodiments, a push rod assembly is further arranged on the vertical channel, the push rod assembly has a telescopic end, the telescopic end is movable along the horizontal direction and is used for extending into the vertical channel through the inspection opening to push the pathological tissue wax block into the wedge face wax removing device.

[0009] In some embodiments, the bottom of the vertical channel and the bottom plate are both provided with liquid leakage holes; the pathological tissue wax block preprocessing device further comprises a waste liquid collecting device, the waste liquid collecting device comprises a funnel, the funnel is arranged below the vertical channel and the bottom plate and is used for receiving waste liquid after the pathological tissue wax block is melted; a waste liquid storage tank and a waste liquid conveying pipe, the funnel and the waste liquid storage tank are communicated through the waste liquid conveying pipe, and a heating wire is embedded in the tank wall of the waste liquid storage tank.

[0010] In some embodiments, the slicing device further comprises a transparent door body, and the transparent door body is arranged at the observation port and is openable and closable.

[0011] In some embodiments, the slicing device further comprises a transparent door body, and the transparent door body is arranged at the observation port and is openable and closable.

[0012] In some embodiments, the slicing device further comprises a transparent door body, and the transparent door body is arranged at the observation port and is openable and closable.

[0013] In some embodiments, the slicing device further comprises a transparent door body, and the transparent door body is arranged at the observation port and is openable and closable.

[0014] In some embodiments, the slicing device further comprises a transparent door body, and the transparent door body is arranged at the observation port and is openable and closable.

[0015] (1) The pathological tissue wax block is cleaned by the vertical channel during the conveying process from the wax block inlet to the wax block inlet. The vertical channel can clean multiple pathological tissue wax blocks at the same time, thereby improving the work efficiency.

[0016] (2) The wedge surface of the pathological tissue wax block needs to be placed towards the top plate of the wedge surface wax removing device. The top plate adjusts the included angle between the top plate and the connecting plate by rotating to one side of the connecting plate, or the top plate adjusts the included angle between the top plate and the connecting plate by rotating away from the connecting plate, so that the top plate can be self-adapted to fit on the wedge surface of the pathological tissue wax block. Under the action of the heating assembly, the excess wax on the wedge surface and the bottom surface of the pathological tissue wax block is melted, so that the information on the wedge surface can be clearly displayed. Compared with the related art using a cutter for cutting processing, the surface of the processed pathological tissue wax block is smoother, and the information on the wedge surface can be more clearly displayed. BRIEF DESCRIPTION OF DRAWINGS

[0017] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the prior art, a brief introduction will be given below to the drawings needed to be used in the embodiments or prior art description. Obviously, the drawings in the following description are only some embodiments of the present application, and for those skilled in the art, other drawings can also be obtained without creative labor on the basis of these drawings.

[0018] Figure 1 is an assembly schematic view of the vertical channel and the wedge surface wax removing device according to the embodiment of the present application;

[0019] Figure 2 is an assembly schematic view of the vertical channel and the pathological tissue wax block according to the embodiment of the present application;

[0020] Figure 3 is a structural schematic view of the wedge surface wax removing device according to the embodiment of the present application;

[0021] Figure 4 is an assembly schematic view of the vertical channel and the wedge surface wax removing device according to the embodiment of the present application;

[0022] Figure 5 is a whole structural schematic view of the pathological tissue wax block pretreatment device according to the embodiment of the present application;

[0023] Figure 6 is a structural schematic view of the slice assembly according to the embodiment of the present application;

[0024] Figure 7 is a position relationship schematic view between the spotlight and the pathological tissue wax block according to the embodiment of the present application, the spotlight irradiates on the back side of the pathological tissue wax block.

[0025] DRAWINGS

[0026] The pathological tissue wax block pretreatment device 100, the pathological tissue wax block 200, the wax block body 210, the embedding box 220;

[0027] Vertical channel 1, wax block inlet 11, wax block outlet 12, access hole 13;

[0028] Wedge-shaped surface wax removal device 2, bottom plate 21, first blocking edge 211, connecting plate 22, top plate 23, second blocking edge 231, elastic hinge 24;

[0029] Waste liquid collecting device 3, funnel 31, waste liquid conveying pipe 32, waste liquid storage tank 33;

[0030] Slicing device 4, shell 41, observation port 412, mounting port 413, containing cavity 414, slicing assembly 42, support body 421, cutting knife 422, position adjusting device 423, searchlight group 43, searchlight 431;

[0031] Tissue wax block collecting bin 5;

[0032] Operating device 6;

[0033] Push rod assembly 7, push rod support 71, push rod 72;

[0034] Liquid leakage hole 8. DETAILED DESCRIPTION

[0035] The embodiments of the present application are described in detail below, examples of which are shown in the drawings, wherein the same or similar notations represent the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary and are only used to explain the present application, and cannot be understood as a limitation of the present application.

[0036] In the description of the present application, it is understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation of the present application. In addition, the features defined as "first" and "second" can explicitly or implicitly include one or more of the features. In the description of the present application, unless otherwise stated, the meaning of "a plurality of" is two or more.

[0037] In the description of the utility model, it is necessary to explain that, unless there are definite provisions and limitations, the terms "mount", "connect", "connect" should be understood in a broad sense, for example, it can be fixed connection, or it can be detachable connection, or it can be integrally connected, it can be mechanical connection, or it can be electrical connection, it can be directly connected, or it can be indirectly connected through an intermediate medium, it can be the communication between two elements. For ordinary skilled in the art, the specific meaning of the above terms in the utility model can be understood according to the specific circumstances.

[0038] At present, in the daily work of the pathology department, the tissue wax block section is an important link in the whole working procedure. After the patient is sent to the pathology department after operation, the tissue specimen is subjected to a series of procedures such as sampling, fixing, dehydrating, transparentizing, embedding, sectioning and staining, and then the pathological section is handed over to the pathologist for pathological diagnosis.

[0039] The pathological living tissue sent by the clinic first needs to be made into a pathological tissue wax block 200. After the pathological tissue wax block 200 is sectioned, various degrees of staining are carried out, and finally the tissue wax block is archived as part of the pathological archives. In the process of pathological tissue sectioning, the pathological tissue wax block 200 needs to go through three steps of edge trimming, rough trimming of the tissue surface and fine trimming of the tissue surface.

[0040] Edge trimming refers to: the sample tissue is embedded in the embedding box 220 through paraffin, and after embedding, there is excess paraffin around the embedding box 220. These excess paraffin not only blocks the patient information on the embedding box, but also causes the tissue wax block to be unable to be stably installed on the paraffin sectioning machine, so before sectioning, medical staff will use a wax grinding instrument to remove the paraffin around the tissue wax block embedding box 220, so as to carry out subsequent rough trimming, fine trimming and sectioning work.

[0041] The most commonly used equipment for rough trimming and fine trimming at present is a rotary paraffin sectioning machine. The blade is fixed on the knife seat of the sectioning machine, and the tissue wax block is moved up and down and pushed forward by rotating the sectioning hand wheel. The wax block is pushed forward once according to the pre-set sectioning thickness with each rotation of the sectioning hand wheel, so as to cut out the paraffin section of the required thickness. Rough trimming is to expose the tissue surface of the tissue wax block, and the purpose of fine trimming is to trim the rough tissue surface after rough trimming to be smooth, and finally the tissue is cut into complete thin slices of 3-5 microns and attached to the glass slide.

[0042] The applicant found in practice that the tissue wax block embedding box 220 after demolding needs to be removed by the staff using a wax grinding instrument or a knife. This step consumes more physical strength and energy, increases the labor intensity of medical staff. And each tissue wax block is operated independently, the work efficiency is low. Different workers have differences in trimming the tissue wax block.

[0043] The current processing mode is that workers use a paraffin slicer to independently operate each tissue wax block, and different paraffin slicers or different workers have differences in the trimming of the tissue wax block, and the trimming effects are obviously different. The pathological tissue wax block pretreatment device can batch, orderly and quickly coarsely trim and finely trim the tissue surface of the tissue wax block, and facilitates subsequent paraffin tissue slicing.

[0044] Reference will be made below to Figures 1-7 The pathological tissue wax block pretreatment device 100 according to the embodiment of the present application is described.

[0045] As Figures 1-3 shown, the present embodiment provides a pathological tissue wax block pretreatment device 100 including a vertical channel 1, a wedge surface wax removal device 2 and a heating assembly.

[0046] Referring to Figure 1 and Figure 3 , the vertical channel 1 has a wax block inlet 11 and a wax block outlet 12, the wax block inlet 11 is arranged at the top end of the vertical channel 1, and the wax block outlet 12 is arranged at the side wall of the vertical channel 1. From the wax block inlet 11 to the wax block outlet 12, the cross-sectional area of the vertical channel 1 gradually decreases; the wedge surface wax removal device 2 is arranged at the wax block outlet 12, and the wedge surface wax removal device 2 includes a bottom plate 21, a connecting plate 22 and a top plate 23. The bottom plate 21, the connecting plate 22 and the top plate 23 all extend in the horizontal direction. The bottom plate 21 is fixedly connected to the connecting plate 22, and the top plate 23 is rotatably connected to the connecting plate 22. The top plate 23 is used to fit the wedge surface of the pathological tissue wax block 200. The heating assembly is used to heat the vertical channel 1, the top plate 23 and the bottom plate 21 of the wedge surface wax removal device 2.

[0047] As Figure 2 shown, in one specific application scenario, a plurality of pathological tissue wax blocks 200 enter the vertical channel 1 from the wax block inlet 11 in a specific posture, that is, the wedge surfaces of the plurality of pathological tissue wax blocks 200 for displaying information are all upward, and the wax block body 210 of the pathological tissue wax block 200 protrudes from the front side or the rear side of the pathological tissue wax block 200. The cross-sectional area of the vertical channel 1 gradually decreases, and the design of the converging vertical channel 1 can realize the directional processing of the wax block in a limited space. After the heating assembly melts the excess paraffin on the left and right sides of the embedding box 220, the pathological tissue wax block 200 moves downward under the action of gravity and the pressure of other pathological tissue wax blocks 200 above it, and the pathological tissue wax block 200 can exit the vertical channel 1 from the wax block outlet 12 and enter the wedge surface wax removal device 2.

[0048] Referring to Figure 1 , in one specific example, the interval between the left side wall and the right side wall of the vertical channel 1 gradually decreases on the active path from the wax block inlet 11 to the wax block outlet 12, and the wax block outlet 12 is arranged on the left side wall.

[0049] In combination Figure 3 When the pathological tissue wax block 200 enters the wedge surface wax removing device 2, the wedge surface of the pathological tissue wax block 200 needs to be placed towards the top plate 23 of the wedge surface wax removing device 2. The top plate 23 is adjusted by rotating to one side of the connecting plate 22, or the top plate 23 is adjusted by rotating away from one side of the connecting plate 22, so that the included angle between the top plate 23 and the connecting plate 22 is reduced, and thus the top plate 23 can be adaptively attached to the wedge surface of the pathological tissue wax block 200. Under the action of the heating assembly, the excess wax on the wedge surface and the bottom surface of the pathological tissue wax block 200 is melted until the embedding box 220 is exposed.

[0050] After the edge trimming is completed, the pathological tissue wax block 200 can enter the rough trimming, fine trimming and slicing steps.

[0051] Referring to Figure 2 In some specific examples, a plurality of pathological tissue wax blocks 200 can be accommodated in the vertical channel 1 and heated at the same time; the wedge surface wax removing device 2 melts the excess wax on the wedge surface and the bottom surface of the embedding box 220 by heating the wedge surface and the bottom surface of the embedding box 220,

[0052] Therefore, the pathological tissue wax block pretreatment device 100 provided by the embodiment has the following advantages:

[0053] (1) The pathological tissue wax block 200 undergoes cleaning of the excess paraffin on the left and right sides of the embedding box 220 in the vertical channel 1 during the conveying process from the wax block inlet 11 to the wax block inlet 11. The vertical channel 1 can clean a plurality of pathological tissue wax blocks 200 at the same time, improving work efficiency.

[0054] (2) The wedge surface of the pathological tissue wax block 200 needs to be placed towards the top plate 23 of the wedge surface wax removing device 2. The top plate 23 is adjusted by rotating to one side of the connecting plate 22, or the top plate 23 is adjusted by rotating away from one side of the connecting plate 22, so that the included angle between the top plate 23 and the connecting plate 22 is reduced, and thus the top plate 23 can be adaptively attached to the wedge surface of the pathological tissue wax block 200. Under the action of the heating assembly, the excess wax on the wedge surface and the bottom surface of the pathological tissue wax block 200 is melted, and thus the information on the wedge surface can be clearly displayed. Compared with the cutting processing in the related art, the surface of the processed pathological tissue wax block 200 is smoother, and the information on the wedge surface can be more clearly displayed.

[0055] (3) As described above, the pathological tissue wax block pretreatment device 100 of the embodiment can more efficiently trim the edges of the pathological tissue wax block 200, reduce the physical and mental effort, and reduce the labor intensity of medical personnel.

[0056] In one specific example, the heating assembly employs heating wires, which are embedded in the side walls of the vertical channel 1 and on the top plate 23 and the bottom plate 21 of the wedge-shaped wax removing device 2.

[0057] Referring to Figure 3 , further, the bottom plate 21, the connecting plate 22 and the top plate 23 enclose a U-shaped channel, and the opening of the U-shaped channel is provided with a baffle on both sides. Specifically, the opening of the U-shaped channel is used to avoid the wax block body 210. The pathological tissue wax block 200 can be prevented from falling out of the U-shaped opening of the wedge-shaped wax removing device 2 as a whole by providing the baffle. In one specific example, the side of the bottom plate 21 away from the connecting plate 22 is provided with a first baffle 211 extending from the side of the bottom plate 21 to the direction of the top plate 23; and the side of the top plate 23 away from the connecting plate 22 is provided with a second baffle 231 extending from the side of the top plate 23 to the direction of the bottom plate 21.

[0058] Referring to Figure 3 , further, the wedge-shaped wax removing device 2 comprises a resilient hinge 24; the top plate 23 and the connecting plate 22 are connected through the resilient hinge 24, and the resilient hinge 24 is used to apply an elastic force to the top plate 23 so that the top plate 23 has a tendency to rotate towards the connecting plate 22, so that the top plate 23 can rotate to one side of the connecting plate 22 under the action of the elastic force, and the top plate 23 self-adapts to the wedge-shaped surface of the pathological tissue wax block 200.

[0059] In combination with Figure 3 , further, the minimum included angle between the top plate 23 and the connecting plate 22 is the same as the inclination angle of the wedge-shaped surface of the pathological tissue wax block 200.

[0060] Further, the side walls on the opposite sides of the vertical channel 1 are provided with a wax block outlet 12 and an inspection opening 13, and the inspection opening 13 is aligned with the wax block outlet 12 in the horizontal direction. In combination with the above-mentioned embodiment, the wax block outlet 12 is arranged on the left side wall of the vertical channel 1, and the inspection opening 13 is arranged on the right side wall of the vertical channel 1. The inspection opening 13 is aligned with the wax block outlet 12 in the left-right direction.

[0061] Referring to Figure 1 and Figure 4 , further, the pathological tissue wax block 200 further comprises a push rod assembly 7, which is arranged on the vertical channel 1; the push rod assembly 7 has a telescopic end, which is movable in the horizontal direction, and the telescopic end can be extended into the vertical channel 1 through the inspection opening 13, and then the telescopic end pushes the pathological tissue wax block 200 into the wedge-shaped wax removing device 2. In combination with the above-mentioned embodiment, the push rod assembly 7 is arranged on the side wall of the vertical channel 1 and on the side where the inspection opening 13 is arranged, i.e. on the right side wall of the vertical channel 1. By arranging the push rod assembly 7, the labor intensity can be further reduced and the efficiency can be improved.

[0062] Specifically, the push rod assembly includes a push rod support 71 fixed on the right side wall of the vertical channel 1 and a push rod 72 mounted on the push rod support 71 and having a telescopic end.

[0063] Further, the bottom of the vertical channel 1 is provided with a limiting structure to prevent the pathological tissue wax block 200 from falling out of the vertical channel 1 from the bottom. The limiting structure can be to close the bottom of the vertical channel 1, or to provide a filter screen at the bottom of the vertical channel 1. The limiting structure can also be a constricted opening structure, which is smaller than the pathological tissue wax block 200.

[0064] Further, the bottom of the vertical channel 1 is closed to form a bottom wall, and the bottom wall and the wedge-shaped surface wax removing device 2 are fixedly connected to the bottom plate 21.

[0065] In combination Figure 5 Further, the bottom of the vertical channel 1 is provided with a liquid leakage hole 8, and the bottom plate 21 of the wedge-shaped surface wax removing device 2 is also provided with a liquid leakage hole 8. The pathological tissue wax block pretreatment device 100 further includes a waste liquid collecting device 3, which includes a funnel 31, a waste liquid storage tank 33 and a waste liquid conveying pipe 32. The funnel 31 is arranged below the vertical channel 1 and the bottom plate 21, and can receive the waste liquid after the pathological tissue wax block 200 is melted. The funnel 31 and the waste liquid storage tank 33 are connected through the waste liquid conveying pipe 32, and the tank wall of the waste liquid storage tank 33 is embedded with heating wires.

[0066] When the pathological tissue wax block is heated, the excess paraffin on the periphery will melt into a liquid state. The first square tube 11 and the second square tube 12 are provided with liquid leakage holes 13 at the bottom, which are used to provide an outlet channel for the melted paraffin liquid, so that it can be smoothly discharged from the heating channel 1, avoiding accumulation in the heating channel 1, affecting the heating effect and the normal progress of the wax block processing. The funnel 31 has a large opening area, which can ensure that the waste liquid flows accurately into it, preventing the waste liquid from splashing or dripping into the surrounding environment, keeping the working area clean. The waste liquid conveying pipe 32 connects the funnel 31 and the waste liquid storage tank 33, so that the waste liquid collected by the funnel 31 can flow smoothly into the waste liquid storage tank 33 for storage. In this way, the waste liquid can be collected centrally, which is convenient for subsequent unified treatment and avoids environmental pollution caused by random discharge of waste liquid. The waste liquid storage tank 33 is heated by heating wires, which can keep the paraffin waste liquid in a liquid state, ensuring that it can be stored and flowed smoothly in the waste liquid storage tank 33, which is convenient for subsequent processing and cleaning work.

[0067] Example two

[0068] As Figures 5-6As shown, further, the pathological tissue wax block pre-processing device 100 also includes a slicing device 4, which includes a housing 41, a slicing assembly 42, and a spotlight assembly 43. The housing 41 defines a receiving cavity 414 therein, and the housing 41 is provided with a viewing port 412 and a mounting port 413, which are both in communication with the receiving cavity 414; the wedge-shaped wax removing device is mounted at the mounting port of the housing, so that the pathological tissue wax block enters the housing from the wedge-shaped wax removing device under the action of the push rod assembly through the mounting port; the slicing assembly 42 and the spotlight assembly 43 are mounted in the receiving cavity 414; the spotlight assembly 43 includes at least two spotlights 431, and the irradiation direction of at least one spotlight 431 is toward the viewing port 412, and the irradiation direction of at least one spotlight 431 is perpendicular to the viewing port 412; the slicing assembly 42 is used for slicing the pathological tissue wax block.

[0069] Referring to Figure 7 After the pathological tissue wax 200 completes the edge correction in the heating channel 1, the pathological tissue wax block comes out from the wax block outlet 122 and enters the receiving cavity 414 through the mounting port 413. The position of the pathological tissue wax block is adjusted so that the tissue surface of the pathological tissue wax block is placed facing the viewing port 412, the spotlight assembly 43 is turned on, at least one spotlight 431 irradiates the pathological tissue wax block from the back of the pathological tissue wax block, and at least one spotlight 431 irradiates the tissue surface from the side of the pathological tissue wax block.

[0070] For example, at least one spotlight 431 is installed at the top of the receiving cavity 414 so that the spotlight 431 can irradiate the tissue surface from the upper side of the pathological tissue wax block.

[0071] In the related art, because the light transmittance of paraffin is weak, and the difference in reflection effect between the tissue and the paraffin under natural light is not obvious, medical personnel cannot clearly observe the overall morphology and section morphology of the tissue, which may result in insufficient trimming depth, and the pathological tissue wax block needs to be trimmed again in the subsequent paraffin tissue slicing process to completely expose the tissue surface. Therefore, the spotlight assembly 43 irradiates the tissue in the pathological tissue wax block from different angles to improve the visibility of the tissue, so that medical personnel can improve the positioning accuracy of the section when performing subsequent processing such as rough trimming and fine trimming on different pathological tissue wax blocks. Finally, the slicing assembly 42 is used for slicing.

[0072] It should be emphasized that the tissue surface of the pathological tissue wax block is irradiated by the spotlight 431, and the difference in reflection ability of the tissue and the paraffin to light is used to display the section morphology of the tissue.

[0073] In combination with Figure 5As shown, further, the slicing device 4 also comprises a transparent door body which is openably and closably arranged at the observation port 412. The transparent door body is arranged at the observation port 412 to isolate the slicing operation area in the containing cavity 414 from the external environment, thereby reducing the entry of dust, sundries and the like from the external environment into the containing cavity 414 during the slicing process, polluting the pathological tissue wax block or the slicing device 4, ensuring that the slicing operation is performed in a relatively clean environment, and thereby improving the quality and accuracy of the slicing.

[0074] As shown, Figure 5 Further, the slicing assembly 42 comprises a support body 421 for supporting the pathological tissue wax block, and a driving assembly for driving the cutter 422 to move. The main function of the support body 421 is to support the pathological tissue wax block and provide a stable placement platform for the wax block, so that the wax block can maintain a fixed position and posture and will not shake or shift, thereby ensuring uniform thickness of the sliced pieces and stable slicing quality, and enabling the accurate slicing of the tissue part to be observed. The cutter 422 is the core component of the slicing device, and its function is to cut the pathological tissue wax block into thin pieces with appropriate thickness for subsequent observation and pathological analysis under a microscope. The driving assembly is used to drive the cutter 422 to move and provide power and control for the cutting action of the cutter 422, and to adjust the cutting action of the cutter 422 according to the characteristics of different pathological tissue wax blocks and slicing requirements, so as to achieve accurate cutting of the wax block. Through the precise control of the driving assembly, the thickness of the sliced pieces can meet the requirements of experiments or diagnosis, and the accuracy and consistency of the slicing can be improved, thereby providing high-quality sliced samples for pathological analysis.

[0075] As shown, Figure 7 In one specific example, the support body 421 comprises a support body bottom plate, a support body connecting plate and a support body top plate; the support body bottom plate and the support body top plate are connected through the support body connecting plate, and the support body top plate and the support body connecting plate are both provided with a clearance hole or are both configured as a transparent structure to pass the light of the spotlight. The support body bottom plate, the support body connecting plate and the support body top plate enclose a pathological tissue wax block mounting cavity which is matched with the cross-sectional profile of the embedding box, the support body connecting plate is arranged on the side of the pathological tissue wax block away from the wax block body, the wedge surface of the pathological tissue wax block is arranged against the support body top plate, and the bottom surface of the pathological tissue wax block is arranged against the support body bottom plate, thereby fixing the wax block body. As shown, Figure 7 The dashed portion of the support body 421 represents a transparent structure or a clearance hole structure.

[0076] As shown, Figure 6As shown, the driving assembly includes a driving motor and a position adjusting device 423. The position adjusting device includes an execution arm, which includes a telescopic arm and a rotating joint. The distance between the blade and the surface of the tissue wax block can be adjusted through the telescopic arm. The angle between the blade and the surface of the tissue wax block can be adjusted through the rotating joint. In the related art, in the process of slicing the tissue, because the types of specimens submitted by different patients are different, the textures of the specimens are also different, which leads to different degrees of damage to the slicing blade in the process of slicing the paraffin tissue. The damage to the blade is smaller for the tissue with a softer texture, and the damage to the blade is greater for the tissue which is relatively tough or contains bone or calcified foci. The damaged blade cannot perform normal and fine slicing work, and only the blade can be replaced for secondary slicing. By adjusting the position of the blade, the wear of the blade can be reduced.

[0077] As shown in the specific example, an operation device 6 is further arranged on the outer surface of the shell 41. The operation device 6 is in communication connection with the driving assembly to control the action of the driving assembly, and the driving assembly can drive the blade to move and adjust the relative position with the pathological tissue wax block. Figure 5 As shown in the specific example, an operation device 6 is further arranged on the outer surface of the shell 41. The operation device 6 is in communication connection with the driving assembly to control the action of the driving assembly, and the driving assembly can drive the blade to move and adjust the relative position with the pathological tissue wax block.

[0078] Figure 5 As shown, further, the shell 41 further includes a tissue wax block collecting bin 5. The tissue wax block collecting bin 5 is arranged below the accommodating cavity 414 and is used for collecting the pathological tissue wax block falling after the slicing assembly 42 slices. After the pathological tissue wax block is sliced by the slicing assembly 42, the tissue wax block collecting bin 5 can directly receive the falling wax block, avoids the wax block from scattering everywhere, facilitates centralized collection, keeps the operation area clean and orderly, and is beneficial to subsequent processing.

[0079] As shown, further, the shell 41 further includes a tissue wax block collecting bin 5. The tissue wax block collecting bin 5 is arranged below the accommodating cavity 414 and is used for collecting the pathological tissue wax block falling after the slicing assembly 42 slices. After the pathological tissue wax block is sliced by the slicing assembly 42, the tissue wax block collecting bin 5 can directly receive the falling wax block, avoids the wax block from scattering everywhere, facilitates centralized collection, keeps the operation area clean and orderly, and is beneficial to subsequent processing. Figure 5 As shown, the outer surface of the shell 41 further has a main switch. The main switch is used for controlling the opening and closing of the heating channel 1, the driving assembly and the operation device 6.

[0080] A specific working process is as follows:

[0081] 1. Turn on the main switch, and after the preheating of the heating assembly is completed, place the untreated pathological wax block tissue into the vertical channel. After the pathological wax block tissue reaches the bottom of the vertical channel, trim the excess wax blocks on the left and right sides of the embedding box.

[0082] 2. Push the tissue wax block into the wax removing device of the wedge-shaped surface by the push rod assembly, and trim the paraffin on the wedge-shaped surface and the bottom surface of the embedding box.

[0083] 3. Place the pathological tissue wax block after the edge trimming on the support body 421, adjust the position of the pathological tissue wax block, so that one of the spotlights 431 irradiates the back of the pathological tissue wax block, and one of the spotlights 431 irradiates the tissue surface of the pathological tissue wax block from the upper side of the pathological tissue wax block. ​

[0084] 4. The operator adjusts the angle and position of the cutter 422 by operating the device 6 to adjust the cutting area, irradiate the back of the tissue wax block, and complete the rough and fine trimming of the tissue wax block.

[0085] 5. Press the complete button, the push rod assembly pushes the trimmed pathological tissue wax block out of the wedge-shaped wax removal device and drops into the tissue wax block collection bin 5, and the telescopic end of the push rod exits the vertical channel.

[0086] 6. After the work is completed, the pretreated tissue wax block is taken out from the tissue wax block collection bin 5, and the waste in the waste liquid collection bin is cleaned.

[0087] Other configurations and operations of the pathological tissue wax block pretreatment device 100 according to the embodiments of the present application are known to those skilled in the art, and will not be described in detail here. In the description of the present application, "first feature", "second feature" can include one or more features. Among them, the up-down direction, the left-right direction and the front-rear direction are based on the up-down direction, the left-right direction and the front-rear direction shown in the figure.

[0088] In the description of the present application, unless otherwise explicitly specified and limited, the "first feature" above or below the "second feature" can include that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, the first feature above, above and above the second feature includes that the first feature is directly above and obliquely above the second feature, or only indicates that the first feature is higher than the second feature in horizontal height.

[0089] In the description of the present application, the description of the terms "one embodiment", "some embodiments", "exemplary embodiment", "example", "specific example", or "some examples" means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the exemplary description of the above terms does not necessarily mean the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0090] Although the embodiments of the present application have been shown and described, those skilled in the art can understand that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and purposes of the present application, and the scope of the present application is defined by the claims and their equivalents.

Claims

1. A pretreatment device for pathological tissue paraffin blocks, characterized in that, The pathological tissue wax block pre-treatment device comprises: a vertical channel having a wax block inlet and a wax block outlet, the wax block inlet being arranged at the top end of the vertical channel, the wax block outlet being arranged on the side wall of the vertical channel, the cross-sectional area of the vertical channel gradually decreasing from the wax block inlet to the wax block outlet; a wedge-shaped wax removing device arranged at the wax block outlet and comprising a bottom plate, a connecting plate and a top plate, the bottom plate, the connecting plate and the top plate all extending in the horizontal direction, the bottom plate being fixedly connected to the connecting plate, the top plate being rotatably connected to the connecting plate and being used for abutting against the wedge-shaped surface of the pathological tissue wax block; a heating assembly used for heating the vertical channel, the top plate and the bottom plate of the wedge-shaped wax removing device.

2. The pathological tissue wax block pretreatment apparatus according to claim 1, characterized by, The bottom plate, the connecting plate and the top plate surround a U-shaped channel, and the opening of the U-shaped channel is provided with a stop edge on both sides.

3. The pathology tissue wax block pretreatment apparatus according to claim 1, characterized by, The wedge-shaped wax removing device comprises an elastic hinge. The top plate and the connecting plate are connected through the elastic hinge, and the elastic hinge is used for applying an elastic force to the top plate so that the top plate has a tendency to rotate towards the connecting plate.

4. The pathology tissue wax block pretreatment apparatus according to claim 1, characterized by, The side walls on the opposite sides of the vertical channel are respectively provided with the wax block outlet and an inspection opening, and the inspection opening is aligned with the wax block outlet in the horizontal direction.

5. The pathology tissue wax block pretreatment apparatus according to claim 4, characterized by, The device further comprises a push rod assembly arranged on the vertical channel. The push rod assembly has a telescopic end which is movable in the horizontal direction and is used for extending into the vertical channel through the inspection opening to push the pathological tissue wax block into the wedge-shaped wax removing device.

6. The pathology tissue wax block pretreatment apparatus according to claim 1, characterized by, The bottom of the vertical channel and the bottom plate are both provided with liquid leakage holes. The pathological tissue wax block pre-treatment device further comprises a waste liquid collecting device which comprises: a funnel arranged below the vertical channel and the bottom plate and used for receiving the waste liquid after the pathological tissue wax block is melted; a waste liquid storage tank and a waste liquid conveying pipe, the funnel and the waste liquid storage tank being connected through the waste liquid conveying pipe, and the tank wall of the waste liquid storage tank being embedded with heating wires.

7. The pathology tissue wax block pretreatment apparatus according to claim 1, characterized by, The device further comprises a slicing device which comprises a housing, a slicing assembly and a spotlight group. The housing defines an accommodating cavity therein. The housing is provided with an observation opening and a mounting opening, and the observation opening and the mounting opening are both connected to the accommodating cavity. The wedge-shaped wax removing device is used for being mounted at the mounting opening of the housing. The slicing assembly and the spotlight group are mounted in the accommodating cavity. The spotlight group comprises at least two spotlights, at least one of which has an irradiation direction towards the observation opening, and at least one of which has an irradiation direction perpendicular to the observation opening.

8. The pathology tissue wax block pretreatment apparatus according to claim 7, characterized by, The slicing assembly is used for slicing the pathological tissue wax block.

9. The pathology tissue wax block pretreatment apparatus according to claim 8, characterized by, The slicing device further comprises a transparent door body which is openably and closably arranged at the observation opening. The slicing assembly comprises a support body, a cutter and a driving assembly. The support body is used for supporting the pathological tissue wax block.

10. The pathological tissue wax block pretreatment apparatus according to claim 9, characterized by, The driving assembly is used for driving the cutter to move. The housing is further provided with a tissue wax block collecting bin. The tissue wax block collecting bin is arranged below the accommodating cavity and is used for collecting the wax block body falling after being sliced by the slicing assembly.