EP tube cryopreservation box

By introducing a detection plate and elastic support sheet into the EP tube cryopreservation box, the problem of EP tube caps not being properly closed is solved. This design accommodates EP tubes of different diameters, ensuring safe cryopreservation and fixation of samples, and preventing contamination and shaking.

CN223962583UActive Publication Date: 2026-03-03重庆市血液中心
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-04-11
Publication Date
2026-03-03

AI Technical Summary

Technical Problem

Existing EP tube cryopreservation boxes cannot detect whether the caps of EP tubes are properly closed, and cannot accommodate EP tubes of different diameters, leading to potential sample contamination and unstable storage.

Method used

An EP tube cryopreservation box was designed, which includes a detection plate and an elastic support plate. The detection plate detects whether the cap is properly closed by using a sliding column and an elastic plate. The elastic support plate is adaptable to EP tubes of different diameters. Combined with an adjustable movable base plate and a sealing structure, it ensures the stable fixation of the EP tube and prevents liquid nitrogen or water vapor from entering.

Benefits of technology

It enables the correct capping detection of EP tubes, adapts to the fixing of EP tubes of different diameters, prevents sample contamination and shaking during freezing, and ensures the safe storage of samples.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of low-temperature storage equipment, in particular to an EP tube cryopreservation box which comprises a box body with an opening in the upper end, a placement plate arranged in the box body, a detection plate arranged above the placement plate and a cover body used for covering the box body, and the placement plate is horizontally arranged in an inner cavity of the upper portion of the box body and fixedly connected with the inner wall of the box body. A plurality of placement holes are vertically formed in the placement plate, the detection plate is hinged to the placement plate so that the detection plate can be overturned to be in a state parallel to the placement plate, through holes I which are in one-to-one correspondence with the placement holes and are coaxially formed are formed in the detection plate, and sliding columns are arranged in the through holes I in a sliding manner; and when the detection plate is overturned to be in a parallel axis state with the placement plate, the upper surface of a cover cap correctly covering the EP tube body is in contact with the lower surface of the sliding column, and the upper surface of the sliding column is flush with the upper surface of the detection plate. By adopting the scheme, the EP pipe body which is not correctly covered with the cap can be quickly detected through the detection plate.
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Description

Technical Field

[0001] This utility model relates to the field of low-temperature storage equipment technology, specifically to an EP tube cryopreservation box. Background Technology

[0002] EP tube cryopreservation boxes (also known as cryopreservation racks or cryopreservation plates) are commonly used to safely and systematically preserve EP tubes (microcentrifuge tubes) in low-temperature environments. They are suitable for storing EP tubes in ultra-low temperature environments such as liquid nitrogen tanks and -80℃ freezers, preventing damage or contamination of EP tubes due to collisions, compression, or temperature fluctuations during cryopreservation. Their ultimate purpose is to preserve trace amounts of liquid samples inside EP tubes, such as serum, cell suspensions, enzymes, reagents, and other biological samples. Existing EP tube cryopreservation boxes do not have the function of detecting whether the EP tube cap is properly closed. If an EP tube is placed in an EP tube cryopreservation box with an improperly closed cap and stored in a low-temperature environment, moisture may enter the EP tube and contaminate the liquid sample inside, leading to sample preservation failure. Furthermore, the existing EP tube cryopreservation boxes have a single aperture for placing EP tubes, which cannot accommodate EP tubes of different diameters. Utility Model Content

[0003] The purpose of this utility model is to provide an EP tube cryopreservation box to solve the problem mentioned in the above-mentioned technical background that the existing EP tube cryopreservation boxes cannot detect whether the cap of the EP tube is properly closed.

[0004] To solve the above-mentioned technical problems, the basic solution adopted by this utility model is: an EP tube cryopreservation box, including a box body with an open top, a placement plate disposed in the box body for placing EP tubes, a detection plate disposed above the placement plate for detecting the cap-on state of the EP tubes, and a cover for closing the box body. The placement plate is horizontally disposed in the upper inner cavity of the box body and fixedly connected to the inner wall of the box body. Multiple placement holes for placing EP tubes are vertically disposed on the placement plate. The detection plate is a plate adapted to the placement plate, and the detection plate is hinged to the placement plate to facilitate detection. The plate can be flipped to a state parallel to the placement plate. The detection plate is provided with a through hole that corresponds one-to-one with the placement hole and is coaxially arranged. A sliding column is slidably arranged in the through hole. An extendable elastic sheet is attached to the upper surface of the detection plate corresponding to the through hole. The middle part of the elastic sheet is fixedly connected to the upper surface of the sliding column, and both ends of the elastic sheet are fixedly connected to the upper surface of the detection plate. When the detection plate is flipped to a state parallel to the placement plate, the upper surface of the correctly fitted cap on the EP tube body contacts the lower surface of the sliding column, and the upper surface of the sliding column is flush with the upper surface of the detection plate.

[0005] In the above scheme, when the EP tube is placed vertically in the placement hole, the cap at the top of the EP tube is located in the space above the placement plate. When the detection plate is flipped over and placed on the placement plate so that the detection plate is parallel to the placement plate, the upper surface of the correctly fitted cap contacts the lower surface of the sliding column, but the upper end of the sliding column remains flush with the upper surface of the detection plate. When the cap of an EP tube is not properly fitted, the highest point of the cap will be higher than the upper surface of other correctly fitted caps, thus pushing the corresponding sliding column upward. The upper end of the corresponding sliding column will extend upward beyond the upper surface of the detection plate. When the operator finds that the upper end of a sliding column extends upward beyond the upper surface of the detection plate, the cap corresponding to the sliding column is in a state of not being properly fitted on the upper port of the EP tube.

[0006] Furthermore, the inner wall of the placement hole is circumferentially distributed with multiple elastic support plates for fixing the EP tube body. The upper end of the elastic support plate is fixedly connected to the inner wall of the placement hole, the middle part of the elastic support plate is in an arc shape that bulges towards the axis of the placement hole, and the lower end of the elastic support plate is slidably connected to the inner wall of the placement hole.

[0007] In the above scheme, when the EP tube is vertically placed into the placement hole, the outer wall of the EP tube contacts and presses the arc-shaped position in the middle of each elastic support piece in a direction away from the axis of the placement hole. The middle part of the elastic support piece is deformed by the compression, causing the lower end of the elastic support piece to slide downward. EP tubes of different diameters can be placed in the placement hole, and the EP tube can be prevented from swaying left and right under the support of the evenly distributed elastic support pieces. The multiple circumferentially distributed elastic support pieces play the role of fixing the EP tube.

[0008] Furthermore, a movable base plate is horizontally arranged in the lower inner cavity of the box body, and the outer wall of the movable base plate is slidably connected to the inner wall of the box body. An adjusting rod is vertically arranged inside the box body. The upper section of the adjusting rod is a smooth rod, and the outer wall of the lower section of the adjusting rod is provided with external threads. The upper section of the adjusting rod is rotatably connected to the placement plate. A threaded through hole that mates with the lower section of the adjusting rod is provided on the movable base plate.

[0009] In the above solution, the height of the movable base plate can be adjusted by turning the adjusting rod to accommodate EP tubes of different lengths, ensuring that the cap at the top of the EP tube contacts the lower surface of the sliding column.

[0010] Furthermore, to prevent liquid nitrogen or water vapor from entering the container, a sealing ring is provided on the upper surface of the container. When the container is stored in liquid nitrogen, the sealing ring can prevent liquid nitrogen or condensation from entering the container.

[0011] Furthermore, the upper surface of the detection plate and the upper surface of the sliding column are both coated with a pigment layer one, and the side wall of the sliding column is coated with a pigment layer two of a different color than the pigment layer one. The upper surface of the placement plate and the upper surface of the sliding column are marked with corresponding hole positions.

[0012] Furthermore, the cover is a component made of a transparent material. This allows for easy observation of the sliding pins on the detection plate to check for any protrusions.

[0013] Furthermore, the box body and the lid body are provided with a latch to fasten the lid body to the box body.

[0014] Furthermore, the elastic support sheet is a component made of an elastic material.

[0015] Furthermore, the upper surface of the movable base plate is provided with an arc-shaped groove corresponding to the bottom of the EP tube.

[0016] Compared with existing technologies, the EP tube cryopreservation box of this solution has at least the following beneficial effects:

[0017] 1. The EP tube cryopreservation box of this solution is equipped with a detection plate for detecting whether the cap of the EP tube is correctly closed. When the cap of an EP tube is not properly closed, the plate is flipped so that it is parallel to the placement plate. The corresponding slide will be pushed up by the improperly closed cap and protrude from the upper surface of the detection plate. The different colors on the side wall of the slide that protrudes from the upper surface of the detection plate will be very conspicuous. The operator can quickly determine the position of the EP tube with the improperly closed cap by looking at the hole markings on the upper surface of the slide.

[0018] II. In this solution, multiple elastic support plates are evenly distributed circumferentially inside the placement hole, allowing EP tubes of different diameters to be placed inside the placement hole. The multiple evenly distributed elastic support plates can still effectively fix the EP tubes of different diameters, preventing the EP tubes from shaking inside the placement hole.

[0019] III. This solution is equipped with a movable base plate that can move up and down. The height of the movable base plate can be adjusted by rotating the adjusting rod to meet the needs of EP tubes of different lengths. Attached Figure Description

[0020] The accompanying drawings, which are included to provide a further understanding of this application and form part of this application, illustrate exemplary embodiments and are used to explain this application, but do not constitute an undue limitation of this application. In the drawings:

[0021] Figure 1 This is a structural schematic diagram of an EP tube cryopreservation box according to the present invention, viewed from the front.

[0022] Figure 2 for Figure 1Enlarged view of section A.

[0023] Figure 3 This is a top view of an EP tube cryopreservation box of this utility model after the cover has been removed.

[0024] Figure 4 This is a top view of an EP tube cryopreservation box of this utility model after removing the cover and the detection plate.

[0025] The meanings of the labels in the attached diagram are as follows:

[0026] Box body-10; Sealing ring-101;

[0027] EP tube body-20; cap-201;

[0028] Placement plate-30; Placement hole-301; Elastic support piece-302;

[0029] Detection plate-40; Through hole one-401; Sliding column-402; Elastic sheet-403;

[0030] Cover -50;

[0031] Movable base plate - 60; Threaded through hole - 601; Arc-shaped groove - 602;

[0032] Adjusting rod -70; Lock -80; Hinge -90. Detailed Implementation

[0033] To make the objectives, technical solutions, and advantages of this application clearer, the technical solutions of this application will be clearly and completely described below in conjunction with specific embodiments and corresponding drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0034] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention.

[0035] This embodiment provides an EP tube cryopreservation box, such as... Figures 1-4 As shown, it includes a box body 10 with an opening at the top, a placement plate 30 disposed inside the box body 10 for placing the EP tube 20, a detection plate 40 disposed above the placement plate 30 for detecting the closed state of the cap 201 of the EP tube 20, and a cover 50 for closing the box body 10.

[0036] The box body 10 is a rectangular box with an opening at the top. The box body 10 can be made of low-temperature resistant and corrosion-resistant polypropylene. The cover 50 is hinged to the box body 10 by a hinge, so that the cover 50 can be flipped to open or close the box body 10. The box body 10 and the cover 50 are equipped with a latch 80 to lock the cover 50 onto the box body 10. The cover 50 is made of a transparent material, such as polyethylene tetrafluoroethylene, polycarbonate, etc., with polycarbonate being preferred. The contents of the box body 10 can be observed through the cover 50 at any time. A sealing ring 101 made of elastic silicone is provided on the upper surface of the box body 10. When the box body 10 is stored in liquid nitrogen, the sealing ring 101 can prevent liquid nitrogen or condensate from entering the box body 10.

[0037] The placement plate 30 is horizontally disposed in the upper inner cavity of the box body 10 and fixedly connected to the inner wall of the box body 10. The placement plate 30 has multiple vertically arranged placement holes 301 for placing the EP tube body 20, such as... Figure 2 As shown, multiple elastic support pieces 302 made of elastic material for fixing the EP tube body 20 are evenly distributed circumferentially on the inner wall of the placement hole 301. The elastic support pieces 302 are preferably made of 1Cr18Ni9 sheet. In this embodiment, 6 elastic support pieces 302 are evenly distributed circumferentially on the inner wall of each placement hole 301. It can also be set to 4 pieces, 8 pieces, or other numbers of elastic support pieces 302. The upper end of the elastic support piece 302 is fixedly connected to the inner wall of the placement hole 301. The upper end of the elastic support piece 302 can be fixedly connected by means of bonding, embedding into the body of the placement plate 30, etc. The middle part of the elastic support piece 302 is an arc shape that bulges towards the axis of the placement hole 301. The lower end of the elastic support piece 302 is slidably connected to the inner wall of the placement hole 301. Next, when the EP tube 20 is vertically placed into the placement hole 301, the outer wall of the EP tube 20 contacts and presses the arc-shaped position in the middle of each elastic support piece 302 in a direction away from the axis of the placement hole 301. The middle part of the elastic support piece 302 is deformed by compression, causing the lower end of the elastic support piece 302 to slide downward. Thus, EP tubes 20 of different diameters can be placed in the placement hole 301, and the EP tube 20 can be prevented from swaying left and right under the support of the evenly distributed elastic support pieces 302. The multiple circumferentially distributed elastic support pieces 302 play the role of fixing the EP tube 20.

[0038] The detection plate 40 is disposed above the placement plate 30. The detection plate 40 is a plate body adapted to the placement plate 30. One edge of the detection plate 40 is hinged to the placement plate 30 through a hinge seat 90, allowing the detection plate 40 to be flipped close to the placement plate 30 and in a parallel state with the placement plate 30. The detection plate 40 is provided with through holes 401 that correspond one-to-one with the placement holes 301 and are coaxially arranged. The inner diameter of the through hole 401 is larger than the outer diameter of the cap 201 at the upper end of the EP tube body 20. A sliding column 402 is slidably disposed within the through hole 401. The height of the sliding column 402 is equal to the thickness of the detection plate 40. Both the upper surface of the detection plate 40 and the upper surface of the sliding column 402 are coated with a first pigment layer. The sidewall of the sliding column 402 is coated with a second pigment layer of a different color than the first pigment layer. Hole position marks are marked on the upper surface of the placement plate 30 and the upper surface of the sliding column 402, allowing the first and second pigment layers to be set to two contrasting colors. Figures 1-3 As shown, a strip-shaped, stretchable elastic sheet 403 is attached to the upper surface of the detection plate 40 corresponding to the through hole 401. The elastic sheet 403 is preferably made of elastic rubber. The middle part of the elastic sheet 403 is fixedly connected to the upper surface of the sliding column 402, and both ends of the elastic sheet 403 are fixedly connected to the upper surface of the detection plate 40. When the detection plate 40 is flipped to a position parallel to the placement plate 30, the upper surface of the correctly fitted cap 201 on the EP tube 20 contacts the lower surface of the sliding column 402. The upper surface of the sliding column 402 is flush with the upper surface of the detection plate 40. When the cap 201 of the EP tube 20 is not properly fitted, the highest point of the cap 201 of the EP tube 20 will be higher than the upper surface of other correctly fitted caps 201. As a result, the cap 201 will push the corresponding sliding column 402 upward, and the upper end of the corresponding sliding column 402 will extend upward beyond the upper surface of the detection plate 40.

[0039] A movable base plate 60 is horizontally arranged in the lower inner cavity of the box body 10. The outer wall of the movable base plate 60 is slidably connected to the inner wall of the box body 10. The upper surface of the movable base plate 60 is provided with an arc-shaped groove 602 corresponding to the bottom of the EP tube body 20. An adjusting rod 70 is vertically arranged inside the box body 10. The adjusting rod 70 is located in the middle of the inner cavity of the box body 10. The upper section of the adjusting rod 70 is a smooth rod, and the outer wall of the lower section of the adjusting rod 70 is provided with external threads. The upper end of the adjusting rod 70 extends upward out of the placement plate 30, and the upper end face of the adjusting rod 70 is provided with a square... Tighten the cross groove of the adjusting rod 70. The upper section of the adjusting rod 70 is rotatably connected to the placement plate 30 through a bidirectional thrust bearing. The movable base plate 60 is provided with a threaded through hole 601 that mates with the lower section of the adjusting rod 70. The lower end of the adjusting rod 70 extends downward through the threaded through hole 601 and out of the movable base plate 60. The height of the movable base plate 60 can be adjusted by turning the adjusting rod 70 to accommodate EP tubes 20 of different lengths, ensuring that the cap 201 at the upper end of the EP tube 20 is positioned just in contact with the lower surface of the sliding column 402.

[0040] In this invention, based on the length of the EP tube 20, the movable base plate 60 is adjusted to a suitable height position by rotating the adjusting rod 70. This ensures that when the EP tube 20 with the cap 201 correctly fitted is vertically placed in the placement hole 301, the lower end face of the EP tube 20 is in contact with the movable base plate 60 within the corresponding arc-shaped groove 602. The cap 201 at the upper end of the EP tube 20 is located in the space above the placement plate 30 and just contacts the lower surface of the sliding column 402. When the plate is flipped so that the detection plate 40 is fitted onto the placement plate 30 and parallel to it, the upper surface of the correctly fitted cap 201... The upper end of the slide post 402 is flush with the upper surface of the detection plate 40. When the cap 201 of the EP tube 20 is not properly closed, the highest point of the cap 201 will be higher than the upper surface of other properly closed caps 201, thus pushing the corresponding slide post 402 upward. The upper end of the corresponding slide post 402 will extend upward beyond the upper surface of the detection plate 40. When the operator finds that the upper end of the slide post 402 extends upward beyond the upper surface of the detection plate 40, the cap 201 corresponding to the slide post 402 is in a state where it is not properly closed at the upper port of the EP tube 20.

[0041] When the EP tube 20 is placed in the placement slot, multiple elastic support plates 302 evenly distributed around the circumference automatically deform under the pressure of the EP tube 20 to avoid the EP tube 20 and restrict the EP tube 20 from all sides to prevent the EP tube 20 from shaking in the placement hole 301. The cover 50 is placed on the upper end of the box 10 and the cover 50 is locked to the box 10 by the latch 80 to prevent liquid from entering the internal space of the box 10.

[0042] The above are merely embodiments of this utility model. Commonly known structures and characteristics are not described in detail here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the structure of this utility model, and these should also be considered within the scope of protection of this utility model. These modifications will not affect the effectiveness of the implementation of this utility model or the practicality of the patent. The scope of protection claimed in this application shall be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. An EP tube cryopreservation box, comprising a box body (10) with an opening at the top and a placement plate (30) disposed within the box body (10) for placing EP tube bodies (20), characterized in that: It also includes a detection plate (40) disposed above the placement plate (30) for detecting the closed state of the cap (201) of the EP tube (20) and a cover (50) for closing the box (10). The placement plate (30) is horizontally disposed in the upper inner cavity of the box (10) and fixedly connected to the inner wall of the box (10). The placement plate (30) is vertically provided with a plurality of placement holes (301) for placing the EP tube (20). The detection plate (40) is a plate adapted to the placement plate (30). The detection plate (40) is hinged to the placement plate (30) so that the detection plate (40) can be flipped to a state parallel to the placement plate (30). The detection plate (40) is provided with a hole (301) on it. A corresponding and coaxially arranged through hole (401) is provided. A sliding column (402) is slidably arranged in the through hole (401). An extendable elastic sheet (403) is attached to the upper surface of the detection plate (40) corresponding to the through hole (401). The middle part of the elastic sheet (403) is fixedly connected to the upper surface of the sliding column (402). Both ends of the elastic sheet (403) are fixedly connected to the upper surface of the detection plate (40). When the detection plate (40) is flipped to a state parallel to the axis of the placement plate (30), the upper surface of the correctly fitted cap (201) on the EP tube body (20) contacts the lower surface of the sliding column (402). The upper surface of the sliding column (402) is flush with the upper surface of the detection plate (40).

2. The EP tube cryopreservation box according to claim 1, characterized in that: The inner wall of the placement hole (301) is circumferentially distributed with multiple elastic support plates (302) for fixing the EP tube body (20). The upper end of the elastic support plate (302) is fixedly connected to the inner wall of the placement hole (301). The middle part of the elastic support plate (302) is in an arc shape that protrudes towards the axis of the placement hole (301). The lower end of the elastic support plate (302) is slidably connected to the inner wall of the placement hole (301).

3. The EP tube cryopreservation box according to claim 1, characterized in that: A movable base plate (60) is horizontally arranged in the lower inner cavity of the box (10). The outer wall of the movable base plate (60) is slidably connected to the inner wall of the box (10). An adjusting rod (70) is vertically arranged inside the box (10). The upper section of the adjusting rod (70) is a smooth rod, and the outer wall of the lower section of the adjusting rod (70) is provided with an external thread. The upper section of the adjusting rod (70) is rotatably connected to the placement plate (30). A threaded through hole (601) that mates with the lower section of the adjusting rod (70) is provided on the movable base plate (60).

4. The EP tube cryopreservation box according to claim 1, characterized in that: A sealing ring (101) is provided on the upper end face of the box body (10).

5. The EP tube cryopreservation box according to claim 1, characterized in that: The upper surface of the detection plate (40) and the upper surface of the slide column (402) are coated with a pigment layer one. The side wall of the slide column (402) is coated with a pigment layer two of a different color than the pigment layer one. The upper surface of the placement plate (30) and the upper surface of the slide column (402) are marked with hole positions.

6. The EP tube cryopreservation box according to claim 1, characterized in that: The cover (50) is a component made of transparent material.

7. The EP tube cryopreservation box according to claim 1, characterized in that: The box body (10) is provided with a latch (80) that engages with the cover body (50) to fasten the cover body (50) to the box body (10).

8. The EP tube cryopreservation box according to claim 2, characterized in that: The elastic support sheet (302) is a component made of elastic material.

9. The EP tube cryopreservation box according to claim 3, characterized in that: The upper surface of the movable base plate (60) is provided with an arc-shaped groove (602) corresponding to the bottom of the EP tube body (20).