Titration device for medicine quality analysis

Abstract

The utility model relates to the technical field of experimental analysis devices, and discloses a titration device for medicine quality analysis, which comprises a base, an adjusting mechanism, a clamping mechanism and an oscillating mechanism, the middle part of the other side of the upper end of the base is fixedly connected with a stand column, and the upper end of the base is provided with the adjusting mechanism; and the adjusting mechanism comprises a lifting frame, a fastening threaded rod, a fixing block and a lifting threaded rod, a moving groove is formed in the inner wall of the other side of the lifting frame, and the middle of the outer wall of a rod body of the fastening threaded rod is in threaded connection with the lifting frame. According to the utility model, the fastening threaded rod in the adjusting mechanism drives the friction plate to move so as to change the height of the burette, and the lifting threaded rod drives the clamping seat to move up and down and is matched with the two clamping plates so as to adapt to conical flasks with different sizes; a servo motor in the oscillation mechanism drives a spur rack meshed with an arc-shaped rack to slide back and forth by utilizing a connecting rod, and a fixed frame is rotationally connected with a lifting fixed block, so that oscillation mixing is facilitated.

Description

Technical Field

[0001] This utility model relates to the field of experimental analysis device technology, and in particular to a titration device for pharmaceutical quality analysis. Background Technology

[0002] Titration is a quantitative analysis method that involves adding a titrant of known concentration dropwise to a solution containing the analyte until the chemical reaction is complete. The content of the analyte is determined by calculating the volume of titrant used. A titration apparatus for pharmaceutical quality analysis is a laboratory instrument used in pharmaceutical quality analysis to perform titration analysis.

[0003] However, since conical flasks are mainly used to hold the test solution in titration analysis, most of the existing pharmaceutical quality analysis titration devices on the market are not convenient for fixing conical flasks of different sizes, which reduces the applicability of the device. In addition, most of the existing pharmaceutical quality analysis titration devices on the market are not convenient for shaking the solution in the conical flask, resulting in poor mixing of the test solution and titrant, which increases the time required to obtain the required experimental results.

[0004] Therefore, those skilled in the art have provided a titration apparatus for pharmaceutical quality analysis to solve the problems mentioned in the background art. Utility Model Content

[0005] The purpose of this invention is to address the shortcomings of existing technologies by proposing a titration device for pharmaceutical quality analysis. This device adjusts the height of the burette by moving the friction plate via a fastening threaded rod in the adjusting mechanism, and moves the clamping seat up and down using a lifting threaded rod. Combined with two clamping plates in the clamping mechanism, it can accommodate conical flasks of different sizes. Furthermore, a servo motor in the oscillation mechanism drives a straight rack connected to an arc-shaped rack via a connecting rod to slide back and forth. This, along with the rotating connection between the fixed frame and the lifting fixed block, facilitates oscillation and mixing.

[0006] To achieve the above objectives, the present invention provides the following technical solution:

[0007] A titration apparatus for pharmaceutical quality analysis includes a base, an adjustment mechanism, a clamping mechanism, and a oscillation mechanism. A column is fixedly connected to the middle of the other side of the upper end of the base. An adjustment mechanism is provided at the upper end of the base. The adjustment mechanism includes a lifting frame, a fastening threaded rod, a fixing block, and the lifting threaded rod. A moving groove is formed on the inner wall of the other side of the lifting frame. The middle of the outer wall of the fastening threaded rod is threaded to the lifting frame. A friction plate is fixedly connected to one side of the fastening threaded rod. A first knob is fixedly connected to the other side of the fastening threaded rod. A lifting groove is formed in the middle of the outer wall of one side of the fixing block. The upper end of the lifting threaded rod passes through the fixing block and is fixedly connected to a second knob.

[0008] A base plate is fixedly connected to the lower end of the fixed block. A connecting block is fixedly connected to the outer wall of one side of the lifting frame. A burette is snapped into one side of the connecting block. A clamping mechanism is provided on one side of the fixed block. The clamping mechanism includes a bidirectional threaded rod. A clamping seat is threadedly connected to the outer wall of the lifting threaded rod. A clamping groove is opened on the outer wall of one side of the clamping seat. The front and rear ends of the bidirectional threaded rod pass through the clamping seat and are fixedly connected to a third knob. A clamping plate is threadedly connected to the front and rear ends of the outer wall of the bidirectional threaded rod. An oscillation mechanism is provided inside the base. The oscillation mechanism includes a straight rack.

[0009] Through the above technical solution, the first knob in the adjustment mechanism drives the fastening threaded rod to rotate on the lifting frame, changing the degree of contact between the friction plate and the column surface, so that the lifting frame can move up and down with the burette on the connecting block. The second knob drives the lifting threaded rod to rotate, allowing the clamping seat threadedly connected to the lifting threaded rod to move up and down along the lifting groove. In conjunction with the third knob in the clamping mechanism, the bidirectional threaded rod is driven to rotate, changing the distance between the two clamping plates, thus clamping the conical flask and improving the applicability of the device to conical flasks of different sizes.

[0010] Furthermore, a fixing frame is fixedly connected to the middle of the outer wall of the column, an arc-shaped rack is fixedly connected to the middle of the lower end of the base plate, a rotating groove is opened at the front end of the interior of the base, a servo motor is provided at the front end of the top surface inside the rotating groove, and a connecting rod is fixedly connected to the output shaft of the servo motor.

[0011] Through the above technical solution, the servo motor in the oscillation mechanism drives the linkage to move. The linkage is hinged to the rack, allowing the rack to slide back and forth along the rotating groove. The arc-shaped rack fixedly connected to the base plate meshes with the rack. The outer wall of one side of the fixed frame is rotatably connected to the lifting fixed block, allowing the conical flask placed on the base plate to shake back and forth, which facilitates the mixing of the solution inside the conical flask.

[0012] Furthermore, a PLC control panel is fixedly connected to the rear end of one side of the upper end of the base, and a storage battery is installed in the cavity at the front end of the base.

[0013] The above technical solution allows operators to easily control the device's operation by using a PLC control panel fixedly connected to the base. The battery inside the base provides power to the device, ensuring its normal operation.

[0014] Furthermore, the inner wall of the lifting frame is slidably connected to the column, and the friction plate slides inside the moving groove;

[0015] Through the above technical solution, the first knob drives the fastening threaded rod to rotate on the lifting frame, allowing the friction plate to move inside the moving groove, changing the degree of contact between the friction plate and the column surface. By utilizing the sliding connection between the inner wall of the lifting frame and the column, when the friction plate moves away from the column surface, the lifting frame can drive the burette on the connecting block to move up and down. When the friction plate is in close contact with the column surface, the lifting frame is fixed on the column.

[0016] Furthermore, the bottom surface inside the lifting groove is rotatably connected to the lifting threaded rod, and the clamping seat is slidably connected to the lifting groove;

[0017] Through the above technical solution, the second knob drives the lifting threaded rod to rotate in the lifting groove, and the clamping seat is threadedly connected to the lifting threaded rod, so that the clamping seat can move up and down along the lifting groove to change the clamping height of the clamping plate.

[0018] Furthermore, the inner walls of the front and rear ends of the clamping groove are rotatably connected to the bidirectional threaded rod, and the clamping plates are slidably connected to the clamping groove.

[0019] The above technical solution allows the bidirectional threaded rod to rotate within the clamping groove via a third knob, while both clamping plates are threadedly connected to the bidirectional threaded rod, enabling the distance between the clamping plates to be changed to clamp conical bottles with different neck diameters.

[0020] Furthermore, the outer wall of one side of the fixed frame is rotatably connected to the lifting fixed block, and the straight rack slides inside the rotating groove;

[0021] The above technical solution provides a fulcrum for the rotation of the fixed block by rotatably connecting the fixed frame and the lifting fixed block, allowing the fixed block to rotate along the fulcrum with the clamping seat and the base plate.

[0022] Furthermore, the rear end of the connecting rod is hinged to a straight rack, and the straight rack is meshed with an arc-shaped rack;

[0023] Through the above technical solution, the connecting rod that is hinged to the straight rack is driven by the servo motor, and the arc rack fixedly connected to the base plate meshes with the straight rack. In conjunction with the fixed frame and the lifting fixed block, the conical bottle placed on the base plate can be driven to swing back and forth.

[0024] This utility model has the following beneficial effects:

[0025] 1. The titration device for pharmaceutical quality analysis proposed in this utility model, by adjusting the first knob in the mechanism to drive the fastening threaded rod to rotate on the lifting frame, changes the degree of contact between the friction plate and the column surface, so that the lifting frame can move up and down with the burette on the connecting block. The second knob drives the lifting threaded rod to rotate, so that the clamping seat threadedly connected to the lifting threaded rod moves up and down along the lifting groove. In conjunction with the third knob in the clamping mechanism to drive the bidirectional threaded rod to rotate, the distance between the two clamping plates is changed for clamping, thereby facilitating the fixation of conical flasks of different sizes and improving the applicability of the device.

[0026] 2. The titration device for pharmaceutical quality analysis proposed in this utility model uses a servo motor in the oscillation mechanism to drive the connecting rod. The connecting rod is hinged to a straight rack, allowing the rack to slide back and forth along the rotating groove. An arc-shaped rack fixedly connected to the base plate meshes with the straight rack. The outer wall of one side of the fixed frame is rotatably connected to the lifting fixed block, allowing the conical flask placed on the base plate to shake back and forth. This facilitates the shaking and mixing of the solution in the conical flask, improves the mixing degree of the test solution and the titrant, and reduces the time required to obtain the desired experimental results. Attached Figure Description

[0027] Figure 1 This is a schematic diagram of the main structure of a titration device for pharmaceutical quality analysis proposed in this utility model;

[0028] Figure 2 This is an exploded view of a titration apparatus for pharmaceutical quality analysis proposed in this utility model;

[0029] Figure 3 This is an axial sectional view of the base, fixing frame, clamping seat, and fixing block of a titration device for pharmaceutical quality analysis proposed in this utility model;

[0030] Figure 4 This is an axial sectional view of the base of a titration device for pharmaceutical quality analysis proposed in this utility model;

[0031] Figure 5 for Figure 2 Enlarged view of point A in the middle;

[0032] Figure 6 for Figure 3 Enlarged view of point B in the middle.

[0033] Legend:

[0034] 1. Base; 2. PLC control panel; 3. Battery; 4. Column; 5. Adjustment mechanism; 501. Lifting frame; 502. Connecting block; 503. Moving groove; 504. Fastening threaded rod; 505. Friction plate; 506. First knob; 507. Fixing block; 508. Lifting groove; 509. Lifting threaded rod; 510. Second knob; 511. Base plate; 6. Burette; 7. Clamping mechanism; 701. Clamping seat; 702. Clamping groove; 703. Bidirectional threaded rod; 704. Third knob; 705. Clamping plate; 8. Vibration mechanism; 801. Fixing frame; 802. Arc rack; 803. Rotating groove; 804. Servo motor; 805. Connecting rod; 806. Straight rack. Detailed Implementation

[0035] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of specific embodiments. Obviously, the described specific embodiments are only a part of the specific embodiments of the present invention, and not all of them. Based on the specific embodiments of the present invention, all other specific embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0036] Reference Figure 1 , Figure 2 , Figure 3 , Figure 5 and Figure 6 The present invention provides a specific embodiment of a titration device for pharmaceutical quality analysis, comprising a base 1, an adjustment mechanism 5, a clamping mechanism 7, and a oscillation mechanism 8. A column 4 is fixedly connected to the middle of the other side of the upper end of the base 1. An adjustment mechanism 5 is provided at the upper end of the base 1. The adjustment mechanism 5 includes a lifting frame 501, a fastening threaded rod 504, a fixing block 507, and a lifting threaded rod 509. A moving groove 503 is provided on the inner wall of the other side of the lifting frame 501. The middle of the outer wall of the fastening threaded rod 504 is threadedly connected to the lifting frame 501. A friction plate 505 is fixedly connected to one side of the fastening threaded rod 504. A first knob 506 is fixedly connected to the other side of the fastening threaded rod 504. A lifting groove 508 is provided in the middle of the outer wall of one side of the fixing block 507. The upper end of the lifting threaded rod 509 passes through the fixing block 507 and is fixedly connected to a second knob 510.

[0037] The lower end of the fixed block 507 is fixedly connected to the base plate 511. The outer wall of one side of the lifting frame 501 is fixedly connected to the connecting block 502. The burette 6 is snapped onto one side of the connecting block 502. The fixed block 507 is provided with a clamping mechanism 7. The clamping mechanism 7 includes a bidirectional threaded rod 703. The outer wall of the lifting threaded rod 509 is threadedly connected to the clamping seat 701. The outer wall of one side of the clamping seat 701 is provided with a clamping groove 702. The front end and the rear end of the bidirectional threaded rod 703 both pass through the clamping seat 701 and are fixedly connected to a third knob 704. The front end and the rear end of the outer wall of the bidirectional threaded rod 703 are both threadedly connected to a clamping plate 705. The base 1 is provided with an oscillation mechanism 8. The oscillation mechanism 8 includes a straight rack 806.

[0038] A PLC control panel 2 is fixedly connected to the rear end of one side of the upper part of the base 1. A battery 3 is installed in the cavity at the front end of the base 1. The PLC control panel 2 fixedly connected to the base 1 allows the operator to control the operation of the device. The battery 3 inside the base 1 provides power to the device, ensuring its normal operation. The inner wall of the lifting frame 501 is slidably connected to the column 4. The friction plate 505 slides inside the moving groove 503. The first knob 506 drives the fastening threaded rod 504 to rotate on the lifting frame 501, causing the friction plate 505 to move inside the moving groove 503, changing the degree of contact between the friction plate 505 and the surface of the column 4. By using the sliding connection between the inner wall of the lifting frame 501 and the column 4, when the friction plate 505 moves away from the surface of the column 4, the lifting frame 501 can drive the burette 6 on the connecting block 502 to move up and down. When 505 is pressed against the surface of the column 4, the lifting frame 501 is fixed on the column 4. The bottom surface inside the lifting groove 508 is rotatably connected to the lifting threaded rod 509. The clamping seat 701 is slidably connected to the lifting groove 508. The second knob 510 drives the lifting threaded rod 509 to rotate in the lifting groove 508. The clamping seat 701 is threadedly connected to the lifting threaded rod 509, allowing the clamping seat 701 to move up and down along the lifting groove 508, changing the clamping height of the clamping plate 705. The inner walls of the front and rear ends of the clamping groove 702 are rotatably connected to the bidirectional threaded rod 703. The clamping plates 705 are slidably connected to the clamping groove 702. The third knob 704 drives the bidirectional threaded rod 703 to rotate in the clamping groove 702. Both clamping plates 705 are threadedly connected to the bidirectional threaded rod 703, allowing the distance between the clamping plates 705 to be changed, thus clamping conical bottles with different neck diameters.

[0039] Reference Figure 1 , Figure 2 , Figure 3 and Figure 4A fixed frame 801 is fixedly connected to the middle of the outer wall of the column 4, and an arc-shaped rack 802 is fixedly connected to the middle of the lower end of the base plate 511. A rotating groove 803 is opened at the front end of the interior of the base 1. A servo motor 804 is set at the front end of the top surface inside the rotating groove 803. A connecting rod 805 is fixedly connected to the output shaft of the servo motor 804.

[0040] The outer wall of one side of the fixed frame 801 is rotatably connected to the lifting fixed block 507. The rack 806 slides inside the rotating groove 803. By rotatably connecting the fixed frame 801 and the lifting fixed block 507, a fulcrum is provided for the rotation of the fixed block 507, allowing the fixed block 507 to rotate along the fulcrum with the clamping seat 701 and the base plate 511. The rear end of the connecting rod 805 is hinged to the rack 806. The rack 806 is meshed with the arc rack 802. The servo motor 804 drives the connecting rod 805, which is hinged to the rack 806. The arc rack 802 fixedly connected to the base plate 511 meshes with the rack 806. With the fixed frame 801 and the lifting fixed block 507 rotatably connected, the conical bottle placed on the base plate 511 can be driven to swing back and forth.

[0041] Working principle: When using this titration device for pharmaceutical quality analysis, the operator first rotates the fastening threaded rod 504 on the lifting frame 501 by turning the first knob 506, so that the friction plate 505 is away from the surface of the column 4. Then, the height of the burette 6 is changed according to the height of the conical flask used, and the conical flask containing the solution to be tested is placed on the base plate 511, so that the outlet of the burette 6 is suspended above the conical flask by a certain distance. Then, the first knob 506 is used to make the friction plate 505 stick tightly to the surface of the column 4, and the position of the lifting frame 501 is fixed.

[0042] Next, the second knob 510 drives the lifting threaded rod 509 to rotate in the lifting groove 508. According to the neck position of the conical flask, the clamping seat 701 moves up and down along the lifting groove 508 to change the clamping height of the clamping plate 705. Then, the third knob 704 drives the bidirectional threaded rod 703 to rotate in the clamping groove 702. The clamping plate 705 clamps the neck of the conical flask and fixes the position of the conical flask. Then, the titrant is added into the burette 6 and the valve on the burette 6 is opened to allow the titrant to drip into the conical flask.

[0043] Finally, the device is powered by the storage battery 3. The operator uses the PLC control panel 2 to control the servo motor 804 to drive the connecting rod 805. The connecting rod 805 is hinged to the rack 806, which slides back and forth along the rotating groove 803. The arc rack 802 fixedly connected to the base plate 511 meshes with the rack 806. The fixed frame 801 is rotatably connected to the lifting fixed block 507, so that the conical flask placed on the base plate 511 can shake back and forth to mix until the chemical reaction is complete. The machine is stopped and the volume of the titrant used is obtained by observing the scale on the burette 6. The content of the substance to be measured is determined by calculation.

[0044] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing specific embodiments, those skilled in the art can still modify the technical solutions described in the foregoing specific embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A titration device for pharmaceutical quality analysis, comprising a base (1), an adjustment mechanism (5), a clamping mechanism (7) and a shaking mechanism (8), characterized in that: The middle part of the other side of the upper end of the base (1) is fixedly connected with a stand (4), and the upper end of the base (1) is provided with an adjusting mechanism (5), the adjusting mechanism (5) comprises a lifting frame (501), a fastening threaded rod (504), a fixed block (507) and a lifting threaded rod (509), the inner wall of the other side of the lifting frame (501) is provided with a moving groove (503), the middle part of the outer wall of the rod body of the fastening threaded rod (504) is threadedly connected with the lifting frame (501), one side of the fastening threaded rod (504) is fixedly connected with a friction plate (505), the other side of the fastening threaded rod (504) is fixedly connected with a first knob (506), and the middle part of the outer wall of one side of the fixed block (507) is provided with a lifting groove (508), and the upper end of the lifting threaded rod (509) penetrates through the fixed block (507) and is fixedly connected with a second knob (510). The lower end of the fixed block (507) is fixedly connected with a bottom plate (511), the outer wall of one side of the lifting frame (501) is fixedly connected with a connecting block (502), one side of the connecting block (502) is connected with a burette (6) in a clamped mode, one side of the fixed block (507) is provided with a clamping mechanism (7), the clamping mechanism (7) comprises a bidirectional threaded rod (703), the outer wall of the rod body of the lifting threaded rod (509) is threadedly connected with a clamping seat (701), the outer wall of one side of the clamping seat (701) is provided with a clamping groove (702), the front end and the rear end of the bidirectional threaded rod (703) penetrate through the clamping seat (701) and are fixedly connected with a third knob (704), and the front end and the rear end of the outer wall of the rod body of the bidirectional threaded rod (703) are threadedly connected with clamping plates (705), and the inside of the base (1) is provided with an oscillation mechanism (8), the oscillation mechanism (8) comprises a straight rack (806).

2. A titration device for pharmaceutical quality analysis according to claim 1, characterized in that: The middle part of the outer wall of the stand (4) is fixedly connected with a fixed frame (801), the middle part of the lower end of the bottom plate (511) is fixedly connected with an arc-shaped rack (802), the front end of the inside of the base (1) is provided with a rotating groove (803), the front end of the top surface of the inside of the rotating groove (803) is provided with a servo motor (804), and the output shaft of the servo motor (804) is fixedly connected with a connecting rod (805).

3. A titration device for pharmaceutical quality analysis according to claim 1, characterized in that: The rear end of one side of the upper end of the base (1) is fixedly connected with a PLC control panel (2), and the cavity of the front end of the inside of the base (1) is provided with a storage battery (3).

4. A titration device for pharmaceutical quality analysis according to claim 1, characterized in that: The inner wall of the lifting frame (501) is slidably connected with the stand (4), and the friction plate (505) slides in the inside of the moving groove (503).

5. A titration device for pharmaceutical quality analysis according to claim 1, characterized in that: The bottom surface in the inside of the lifting groove (508) is rotationally connected with the lifting threaded rod (509), and the clamping seat (701) is slidably connected with the lifting groove (508).

6. A titration device for pharmaceutical quality analysis according to claim 1, characterized in that: The inner walls of the front end and the rear end of the clamping groove (702) are rotationally connected with the bidirectional threaded rod (703), and the clamping plates (705) are slidably connected with the clamping groove (702).

7. A titration device for pharmaceutical quality analysis according to claim 2, characterized in that: The outer wall of one side of the fixed frame (801) is rotationally connected with the lifting fixed block (507), and the straight rack (806) slides in the inside of the rotating groove (803).

8. A titration device for pharmaceutical quality analysis according to claim 2, characterized in that: The rear end of the connecting rod (805) is hingedly connected with the straight rack (806), and the straight rack (806) is meshingly connected with the arc-shaped rack (802).

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