Biological analysis equipment

By installing a positioning structure on the operating table, the problems of well plate offset and tilting were solved, achieving precise positioning of the well plate, ensuring accurate sample aspiration by the pipette tip, and improving experimental efficiency and convenience.

CN223992855UActive Publication Date: 2026-03-13WEIYU (SHANDONG) BIOTECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-20
Publication Date
2026-03-13

AI Technical Summary

Technical Problem

The well plates on traditional gel electrophoresis workstations are not properly positioned, causing them to shift or tilt, which affects the accuracy of sample aspiration by the pipette tip and thus the experimental results.

Method used

By installing positioning structures on the operating table, including a fixing plate, a push plate, a hydraulic rod, and a limit plate, the orifice plate can be precisely positioned to prevent it from shifting or tilting.

Benefits of technology

It effectively prevents well plate shifting and tilting, ensuring that the pipette tip can accurately pick up samples from the well plate, improving experimental efficiency and ease of operation, and adapting to well plate positioning of different widths.

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Abstract

The utility model relates to the technical field of biological detection, in particular to biological analysis equipment which comprises an operation table, a fixing plate fixedly connected to the operation table, a plurality of pore plates placed on the operation table, one end of each pore plate abutting against the fixing plate, the other end of each pore plate abutting against a push plate, and the push plate is in sliding connection with the operation table. A second hydraulic rod is fixedly connected to the operation table, a push rod is fixedly connected to the extension end of the second hydraulic rod, the end of the push rod is fixedly connected with the push plate, a plurality of protruding blocks are slidably connected to the interiors of the fixing plate and the push plate, limiting plates are fixedly connected to the protruding blocks, and the limiting plates abut against the pore plate; a suction head is mounted on the shell, and an electrophoresis tank is mounted on the operation table through a moving structure; the pore plate filled with the sample is positioned through the positioning structure, the problem that the suction head is difficult to accurately suck the sample from the pore plate due to deviation and inclination of the pore plate is avoided, and a plurality of pore plates can be placed on the operating table through the positioning structure.
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Description

Technical Field

[0001] This utility model relates to an analytical device, specifically a biological analytical device, belonging to the field of biological detection technology. Background Technology

[0002] Bioanalytical equipment is an indispensable tool in fields such as biological science research, medical diagnosis, and environmental monitoring. As a type of bioanalytical equipment, the fully automated gel electrophoresis spotting workstation focuses on the automated operation of gel electrophoresis experiments. It integrates multiple functions such as gel preparation, electrophoresis, detection and analysis, providing researchers with an efficient, accurate and easy-to-use experimental platform.

[0003] However, in traditional gel electrophoresis workstations, the well plates are placed manually on the operating table without proper positioning. Direct placement of the well plates can easily lead to displacement or tilting due to improper operation by the experimenter, making it difficult for the pipette tip to accurately pick up the sample from the well plate, thus affecting the experimental results. Utility Model Content

[0004] The purpose of this invention is to provide a bioanalytical device to solve the above problems. The device uses a positioning structure to position the well plate containing the sample, thus avoiding the difficulty of the pipette tip accurately drawing the sample from the well plate due to the offset and tilt of the well plate. In addition, the positioning structure allows multiple well plates to be placed on the operating table.

[0005] This utility model achieves the above-mentioned objectives through the following technical solution: a bioanalytical device includes an operating table, on which a positioning structure is installed. The positioning structure includes a fixed plate, which is fixedly connected to the operating table. Multiple perforated plates are placed on the operating table, with one end of each perforated plate abutting against the fixed plate and the other end of each perforated plate abutting against a push plate. A second hydraulic rod is fixedly connected to the operating table, with a push rod fixedly connected to the extended end of the second hydraulic rod. The end of the push rod is fixedly connected to the push plate. Multiple protrusions are slidably connected inside both the fixed plate and the push plate. A limiting plate is fixedly connected to each protrusion, and the limiting plate abuts against the perforated plates. A housing is installed on the operating table via a driving structure, and a suction head is installed on the housing. An electrophoresis tank is installed on the operating table via a moving structure.

[0006] Preferably, the cross-section of the protrusion is L-shaped, the cross-section of the push rod is L-shaped, and the fixing plate is L-shaped.

[0007] Preferably, both the fixed plate and the push plate are slidably connected to a pull plate, and the bottom end of the pull plate is fixedly connected to a plurality of limiting rods. The protrusion has a limiting hole, and the limiting rod engages with the limiting hole.

[0008] Preferably, multiple springs are fixedly connected between the two pull plates and the fixed plate and the push plate, respectively. A pull rod is fixedly connected to the pull plate, and the two pull rods are slidably connected to the fixed plate and the push plate, respectively.

[0009] Preferably, a guide rod is fixedly connected to the push plate, and the guide rod is slidably connected to the operating table.

[0010] Preferably, the driving structure includes a first motor, which is mounted on the operating table. A first lead screw is fixedly connected to the output shaft of the first motor. The first lead screw is rotatably connected to the operating table. A first slider is threadedly connected to the first lead screw. The first slider is slidably connected to the operating table. A first slide rail is fixedly connected to the first slider. A second lead screw is rotatably connected to the first slide rail. A second slider is threadedly connected to the second lead screw. A housing is fixedly connected to the second slider. A first hydraulic rod is installed inside the housing. A suction head is installed at the extended end of the first hydraulic rod.

[0011] Preferably, a second motor is mounted on the first slide rail, and a worm gear is fixedly connected to the output shaft of the second motor. The worm gear is rotatably connected to the first slide rail, and a worm wheel meshes on the worm gear. The worm wheel is fixedly connected to a second lead screw.

[0012] Preferably, the movable structure includes a second slide rail, two second slide rails are fixedly connected to the operating table, a stop block is slidably connected on the second slide rail, an electrophoresis tank is installed on the stop block, and a suction head box is installed on the operating table.

[0013] Preferably, the two stops are fixedly connected by the same connecting rod, and the connecting rod abuts against the connecting block.

[0014] The beneficial effects of this utility model are as follows: a fixed plate is fixedly connected to the operating table, and multiple perforated plates are placed on the operating table. One end of the perforated plate abuts against the fixed plate, and the other end of the perforated plate abuts against a push plate. The push plate is slidably connected to the operating table. A second hydraulic rod is fixedly connected to the operating table, and a push rod is fixedly connected to the extended end of the second hydraulic rod. The end of the push rod is fixedly connected to the push plate. Multiple protrusions are slidably connected inside both the fixed plate and the push plate. A limiting plate is fixedly connected to the protrusion, and the limiting plate abuts against the perforated plate. The positioning structure positions the perforated plate containing the sample, avoiding the difficulty of the suction head accurately picking up the sample from the perforated plate due to the offset and tilt of the perforated plate. Moreover, the positioning structure allows multiple perforated plates to be placed on the operating table. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0016] Figure 2 for Figure 1 The diagram shown is an enlarged view of the structure of part A.

[0017] Figure 3 This is a schematic diagram of the connection structure between the first lead screw and the first slider of this utility model;

[0018] Figure 4 This is a schematic diagram of the connection structure between the first motor and the operating console of this utility model;

[0019] Figure 5 This is a schematic diagram of the connection structure between the baffle and the perforated plate of this utility model;

[0020] Figure 6 for Figure 5 The diagram shown is an enlarged view of the structure of section B.

[0021] Figure 7 This is a schematic diagram of the connection structure between the second lead screw and the second slider of this utility model;

[0022] Figure 8 This is a schematic diagram of the connection structure between the second hydraulic rod and the push rod of this utility model.

[0023] In the diagram: 1. Operating table; 2. Drive structure; 201. First motor; 202. First lead screw; 203. First slider; 204. First slide rail; 205. Second lead screw; 206. Second motor; 207. Worm gear; 208. Worm wheel; 209. Second slider; 210. First hydraulic rod; 3. Housing; 4. Suction head; 5. Electrophoresis tank; 6. Moving structure; 601. Second slide rail; 602. Connecting block; 603. Stop block; 604. Connecting rod; 7. Positioning structure; 701. Fixing plate; 702. Protrusion; 703. Limiting plate; 704. Limiting hole; 705. Limiting rod; 706. Pull plate; 707. Spring; 708. Pull rod; 709. Second hydraulic rod; 710. Push rod; 711. Guide rod; 712. Push plate; 8. Perforated plate; 9. Suction head box. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figures 1-8As shown, a bioanalytical device includes an operating table 1. A positioning structure 7 is mounted on the operating table 1, and the positioning structure 7 includes a fixing plate 701. The fixing plate 701 is fixedly connected to the operating table 1. Multiple perforated plates 8 are placed on the operating table 1. One end of each perforated plate 8 abuts against the fixing plate 701, and the other end of each perforated plate 8 abuts against a push plate 712. A second hydraulic rod 709 is fixedly connected to the operating table 1, and a push rod 710 is fixedly connected to the extended end of the second hydraulic rod 709. The end of the push rod 710 is connected to the push plate. 712 is fixedly connected. Multiple protrusions 702 are slidably connected inside the fixed plate 701 and the push plate 712. A limiting plate 703 is fixedly connected to the protrusion 702. The limiting plate 703 abuts against the perforated plate 8. The cross-section of the protrusion 702 is "L" shaped. The cross-section of the push rod 710 is "L" shaped. The fixed plate 701 is "L" shaped. A housing 3 is installed on the operating table 1 through the driving structure 2. A suction head 4 is installed on the housing 3. An electrophoresis tank 5 is installed on the operating table 1 through the moving structure 6.

[0026] As a technical optimization of this utility model, pull plates 706 are slidably connected inside both the fixed plate 701 and the push plate 712. Multiple limiting rods 705 are fixedly connected to the bottom end of the pull plate 706. Limiting holes 704 are formed on the protrusion 702, and the limiting rods 705 engage with the limiting holes 704. Multiple springs 707 are fixedly connected between the two pull plates 706 and the fixed plate 701 and the push plate 712, respectively. Pull rods 708 are fixedly connected to the pull plates 706. Pull rod 708 is slidably connected to fixed plate 701 and push plate 712 respectively. When placing perforated plate 8, first place the first perforated plate 8 on the operating table 1, so that the side of perforated plate 8 abuts against the end of fixed plate 701. Then pull rod 708, pull rod 708 drives pull plate 706 to slide upward. Pull plate 706 slides and at the same time drives limit rod 705 to no longer engage with limit hole 704 on protrusion 702. At the same time, pull plate 706 drives spring 707 to retract, and then pushes limit plate 703 until limit plate 703 is reached. 703 abuts against the orifice plate 8, and then the other orifice plates 8 are placed in sequence. After all the orifice plates 8 are installed, the pull rod 708 is released, the spring 707 returns to its original position and drives the pull plate 706 and the limiting rod 705 to slide downward, so that the limiting rod 705 engages with the limiting hole 704, thereby preventing the protrusion 702 and the limiting plate 703 from sliding again. Then, the multiple limiting plates 703 on the push plate 712 are adjusted to the same distance as the multiple limiting plates 703 on the fixed plate 701, and the second hydraulic rod 709 is activated. The pressure rod 709 retracts and drives the push rod 710 to move toward the orifice plate 8. The push rod 710 pushes the push plate 712 to slide until the push plate 712 and the limiting plate 703 both abut against the other end of the orifice plate 8, thereby positioning the orifice plate 8 and preventing the suction head 4 from having difficulty picking up samples from the orifice plate 8 when it is tilted during placement. At the same time, multiple orifice plates 8 can be placed on the operating table 1 at the same time through the positioning structure 7, which makes the operation more convenient and efficient. In addition, the push plate 712 can be set to position orifice plates 8 of different widths.

[0027] As a technical optimization of this utility model, a guide rod 711 is fixedly connected to the push plate 712, and the guide rod 711 is slidably connected to the operating table 1; the guide rod 711 has a guiding effect on the push plate 712, making the sliding of the push plate 712 more stable.

[0028] As a technical optimization of this utility model, the driving structure 2 includes a first motor 201, which is mounted on the operating table 1. A first lead screw 202 is fixedly connected to the output shaft of the first motor 201. The first lead screw 202 is rotatably connected to the operating table 1. A first slider 203 is threadedly connected to the first lead screw 202 and slidably connected to the operating table 1. A first slide rail 204 is fixedly connected to the first slider 203. A second lead screw 205 is rotatably connected to the first slide rail 204. A second slider 209 is threadedly connected to the second lead screw 205. A housing 3 is fixedly connected to the second slider 209. A first hydraulic rod 210 is installed inside the housing 3. A suction head 4 is installed at the extended end of the first hydraulic rod 210. A second motor 206 is mounted on the first slide rail 204, and a worm gear 206 is fixedly connected to the output shaft of the second motor 206. 7. The worm 207 is rotatably connected to the first slide rail 204. A worm wheel 208 meshes with the worm 207, and the worm wheel 208 is fixedly connected to the second lead screw 205. The first motor 201 is started, which drives the first lead screw 202 to rotate. The first lead screw 202 drives the first slider 203 to slide. The sliding of the first slider 203 simultaneously drives the first slide rail 204 to slide left and right. Then, the second motor 206 is started, which drives the worm 207 to rotate. The worm 207 meshes with the worm wheel 208, causing the worm wheel 208 to drive the second lead screw 205 to rotate. The second lead screw 205 drives the second slider 209 to slide back and forth. The sliding of the second slider 209 simultaneously drives the housing 3 to slide, thereby causing the housing 3 to move the suction head 4. Then, the first hydraulic rod 210 is started, which drives the suction head 4 to extend and perform sample application. The suction head 4 sucks up the sample from the well plate 8 and then applies it to the electrophoresis tank 5.

[0029] As a technical optimization of this utility model, the movable structure 6 includes a second slide rail 601. Two second slide rails 601 are fixedly connected to the operating table 1. A stop block 603 is slidably connected to the second slide rail 601. An electrophoresis tank 5 is installed on the stop block 603. A suction head box 9 is installed on the operating table 1. A common connecting rod 604 is fixedly connected between the two stop blocks 603. The connecting rod 604 abuts against the connecting block 602. Pulling the handle of the electrophoresis tank 5 causes the electrophoresis tank 5 to move the stop block 603 in the second slide rail 603. Slide the second slide rail 601 until the connecting rod 604 abuts against the connecting block 602 to prevent the electrophoresis tank 5 and the stop block 603 from slipping off the second slide rail 601. Then, place the buffer solution and gel plate into the electrophoresis tank 5 in sequence. Next, push the handle of the electrophoresis tank 5 to make the electrophoresis tank 5 and the stop block 603 slide until the other side of the electrophoresis tank 5 abuts against the end of the second slide rail 601. Thus, the cooperation of the second slide rail 601 and the stop block 603 plays a good role in positioning the electrophoresis tank 5 and prevents the electrophoresis tank 5 from being tilted, which would affect the sample loading work.

[0030] In use, this invention first pulls the handle of the electrophoresis tank 5, causing the stop 603 to slide on the second slide rail 601 until the connecting rod 604 abuts against the connecting block 602, preventing the electrophoresis tank 5 and the stop 603 from slipping off the second slide rail 601. Then, the buffer solution and gel plate are placed into the electrophoresis tank 5 in sequence. Next, the handle of the electrophoresis tank 5 is pushed, causing the electrophoresis tank 5 and the stop 603 to slide until the other side of the electrophoresis tank 5 abuts against the end of the second slide rail 601. Thus, the cooperation of the second slide rail 601 and the stop 603 provides good positioning for the electrophoresis tank 5, preventing the electrophoresis tank 5 from being tilted and affecting the sample loading work. When placing the well plate 8, the first well plate 8 is first placed on the operating table 1, so that the side of the well plate 8 is flush with the fixing plate. The end of 701 contacts the contact point, then pull rod 708 is pulled. Pull rod 708 drives pull plate 706 to slide upward. As pull plate 706 slides, it causes limit rod 705 to no longer engage with limit hole 704 on protrusion 702. At the same time, pull plate 706 drives spring 707 to retract, then pushes limit plate 703 until limit plate 703 contacts hole plate 8. Then, other hole plates 8 are placed in sequence. After all hole plates 8 are installed, pull rod 708 is released. Spring 707 returns to its original position and drives pull plate 706 and limit rod 705 to slide downward, so that limit rod 705 engages with limit hole 704, thus preventing protrusion 702 and limit plate 703 from sliding further. Then, the multiple limit plates 703 on push plate 712 are adjusted to be aligned with the multiple limit plates on fixed plate 701. With the same spacing between the positioning plates 703, the second hydraulic rod 709 is activated. The second hydraulic rod 709 retracts and drives the push rod 710 to move towards the orifice plate 8. The push rod 710 pushes the push plate 712 to slide until both the push plate 712 and the limiting plate 703 abut against the other end of the orifice plate 8, thereby positioning the orifice plate 8 and preventing the suction head 4 from having difficulty picking up samples from the orifice plate 8 due to tilting when placed. At the same time, the positioning structure 7 allows multiple orifice plates 8 to be placed on the operating table 1 simultaneously, making the operation more convenient and efficient. The push plate 712 can also be used to position orifice plates 8 of different widths. The guide rod 711 guides the push plate 712, making the sliding of the push plate 712 more stable. The first motor 201 is activated, and the first motor 201 drives the second hydraulic rod 712 to move towards the orifice plate 8. When the lead screw 202 rotates, the first lead screw 202 drives the first slider 203 to slide. The sliding of the first slider 203 simultaneously drives the first slide rail 204 to slide left and right. Then, the second motor 206 is started, and the second motor 206 drives the worm gear 207 to rotate. The worm gear 207 meshes and transmits power to the worm wheel 208, causing the worm wheel 208 to drive the second lead screw 205 to rotate. The second lead screw 205 drives the second slider 209 to slide back and forth. The sliding of the second slider 209 simultaneously drives the housing 3 to slide, thereby causing the housing 3 to move the suction head 4. Then, the first hydraulic rod 210 is started, and the first hydraulic rod 210 drives the suction head 4 to extend for sample application. The suction head 4 sucks up the sample from the well plate 8 and then applies it to the electrophoresis tank 5. The suction head box 9 is designed to facilitate the placement of the suction head 4.

[0031] It will be apparent to those skilled in the art that this invention is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or essential characteristics of this invention. Therefore, the embodiments should be considered illustrative and non-limiting in all respects, and the scope of this invention is defined by the appended claims rather than the foregoing description. Thus, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0032] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A biological analysis apparatus comprising an operating table (1), characterized in that: The operating table (1) is provided with a positioning structure (7), the positioning structure (7) comprises a fixed plate (701), the fixed plate (701) is fixedly connected to the operating table (1), a plurality of hole plates (8) are placed on the operating table (1), one end of the hole plate (8) abuts against the fixed plate (701), the other end of the hole plate (8) abuts against a push plate (712), a second hydraulic rod (709) is fixedly connected to the operating table (1), the elongated end of the second hydraulic rod (709) is fixedly connected with a push rod (710), the end of the push rod (710) is fixedly connected with the push plate (712), a plurality of protrusions (702) are slidably connected in the fixed plate (701) and the push plate (712), a limiting plate (703) is fixedly connected to the protrusion (702), the limiting plate (703) abuts against the hole plate (8), the operating table (1) is provided with a shell (3) through a driving structure (2), the shell (3) is provided with a suction head (4), and the operating table (1) is provided with an electrophoresis tank (5) through a moving structure (6).

2. The biological analysis device of claim 1, wherein: The cross section of the protrusion (702) is in the form of an "L" shape, the cross section of the push rod (710) is in the form of an "L" shape, and the fixed plate (701) is in the form of an "L" shape.

3. A biological analysis apparatus according to claim 2, wherein: The fixed plate (701) and the push plate (712) are slidably connected with a pull plate (706), the bottom end of the pull plate (706) is fixedly connected with a plurality of limiting rods (705), a limiting hole (704) is formed in the protrusion (702), and the limiting rod (705) is clamped with the limiting hole (704).

4. A biological analysis apparatus according to claim 3, characterized by: A plurality of springs (707) are fixedly connected between the two pull plates (706) and the fixed plate (701) and the push plate (712), respectively, a pull rod (708) is fixedly connected to the pull plate (706), and the two pull rods (708) are slidably connected with the fixed plate (701) and the push plate (712), respectively.

5. A biological analysis apparatus according to claim 4, characterized in that: The push plate (712) is fixedly connected with a guide rod (711), and the guide rod (711) is slidably connected with the operating table (1).

6. The biological analysis device of claim 1, wherein: The driving structure (2) comprises a first motor (201), the operating table (1) is provided with the first motor (201), a first screw rod (202) is fixedly connected to the output shaft of the first motor (201), the first screw rod (202) is rotatably connected with the operating table (1), a first sliding block (203) is threadedly connected to the first screw rod (202), the first sliding block (203) is slidably connected with the operating table (1), a first sliding rail (204) is fixedly connected to the first sliding block (203), a second screw rod (205) is rotatably connected to the first sliding rail (204), a second sliding block (209) is threadedly connected to the second screw rod (205), the shell (3) is fixedly connected to the second sliding block (209), a first hydraulic rod (210) is installed in the shell (3), and the elongated end of the first hydraulic rod (210) is provided with the suction head (4).

7. A biological analysis apparatus according to claim 6, wherein: The first slide rail (204) is provided with a second motor (206), the output shaft of the second motor (206) is fixedly connected with a worm (207), the worm (207) is rotatably connected with the first slide rail (204), the worm (207) is engaged with a worm gear (208), and the worm gear (208) is fixedly connected with the second lead screw (205).

8. The biological analysis device of claim 1, wherein: The moving structure (6) comprises a second slide rail (601), two second slide rails (601) are fixedly connected to the operation table (1), a stop block (603) is slidably connected to the second slide rail (601), and an electrophoresis tank (5) is mounted on the stop block (603).

9. A biological analysis apparatus according to claim 8, wherein: The same connecting rod (604) is fixedly connected between the two stop blocks (603), and the connecting rod (604) abuts against the connecting block (602).