Defiberized blood preparation auxiliary shaking device for acidification hemolysis test

Abstract

The utility model discloses a defibrated blood preparation auxiliary shaking device for an acidification hemolysis test. Comprising a base assembly, a cup body inclining unit, a mold shaking driving unit and a beaker clamping unit which is arranged at the output end of the mold shaking driving unit and used for clamping a beaker. By integrating the cup body tilting unit and the mold shaking driving unit, the technical defect that the requirement for large-batch operation is difficult to meet under the traditional manual shaking method of medical staff is generally solved, and by additionally arranging the tilting action, the technical effect that an internal glass ball continuously rotates along the wall of a beaker when the beaker is manually shaken is ingeniously simulated; the shaking action range is light, and the preparation characteristics of defibrated blood are better met; besides, the inclination angle and the rotating speed of the beaker are controllable, so that the technical requirements of the defibrated blood preparation process on the shaking speed and the shaking action are effectively ensured, the action is standardized, and the test consistency is improved.

Description

Technical Field

[0001] The embodiments of this utility model belong to the field of auxiliary shaking technology, and more specifically, relate to an auxiliary shaking device for preparing defibrinated blood for acidification hemolysis test. Background Technology

[0002] The acidification hemolysis test, also known as the Ham test or acid hemolysis test, is based on the presence of complement-sensitive red blood cells in patients with paroxysmal nocturnal hemoglobinuria (PNH). When incubated in acidic (pH 6.4-6.5) normal serum, complement is activated, leading to the destruction of PNH red blood cells and hemolysis. Normal red blood cells, however, do not undergo hemolysis. The acidification hemolysis test requires the preparation of defibrinated blood, and the quality of this preparation is crucial to the accuracy of the test results.

[0003] To achieve high-quality preparation of defibrinated blood, the common procedure is to first slowly inject venous blood from the patient and healthy individuals with the same blood type into a small flask, and then place several glass beads in the flask beforehand. Subsequently, the flask is immediately and slowly shaken continuously until fibrin appears and adheres to the glass beads.

[0004] Although the above-mentioned commonly used practical methods can effectively achieve the preparation of defibrinated blood, the following technical problems still exist: (1) In the process of preparing defibrinated blood, medical staff shake it manually, and usually need to rotate and shake the beaker continuously for 10-15 minutes. Under the demand of large-scale operations, this increases the physical burden on medical staff; (2) The preparation process of defibrinated blood has strict requirements on shaking speed and shaking action. Using manual shaking method will make it difficult to ensure the consistency of the shaking process, which is not conducive to the comparison of experimental results; (3) Based on the defects of (1) and (2), a beaker-assisted shaking device should be proposed to replace manual shaking, improve the efficiency of defibrinated blood preparation, and promote the standardization of actions to improve the consistency of the experiment. Utility Model Content

[0005] To address the aforementioned deficiencies or improvement needs of existing technologies, this utility model provides an auxiliary shaking device for preparing defibrinated blood in an acidification hemolysis test. By integrating the beaker tilting unit with the shaking drive unit, it largely solves the technical shortcomings of traditional manual shaking methods, which are difficult to handle large-scale operations. Furthermore, by adding a tilting motion, it cleverly simulates the effect of the internal glass bulb continuously rotating along the beaker wall when manually shaking the beaker. The shaking motion is relatively lightweight, better suited to the characteristics of defibrinated blood preparation. In addition, the beaker tilt angle and rotation speed are controllable, effectively ensuring the technical requirements for shaking speed and motion during the defibrinated blood preparation process, standardizing the action, and improving the consistency of the test.

[0006] To achieve the above objectives, an auxiliary shaking device for preparing defibrinated blood in an acidification hemolysis test includes:

[0007] A base assembly consisting of a base plate and support legs; a beaker tilting unit located above the base assembly for controlling the tilt angle of the beaker; a shaking drive unit located at the output end of the beaker tilting unit for simulating the effect of shaking the beaker by hand; and a beaker clamping unit located at the output end of the shaking drive unit for clamping the beaker.

[0008] The mold rocking drive unit includes a mold rocking drive motor fixedly connected to the output end of the cup tilting unit, a driving bevel gear fixedly connected coaxially to the output shaft of the mold rocking drive motor, a support plate with a bevel gear at the bottom, a driven bevel gear meshing and drivingly connected to the bevel gear, a bearing seat for positioning the driven bevel gear, and a rotating shaft for fixing the support plate to the output end of the cup tilting unit; the bevel gear meshes and drives the driving bevel gear.

[0009] The beaker is fixed and clamped by the beaker clamping unit, the beaker tilting angle is controlled by the beaker tilting unit, and the beaker shaking effect is simulated by the manual shaking unit.

[0010] Preferably, the cup tilting unit includes:

[0011] The system includes a tilt drive motor fixed to the upper right side of the substrate, a swing rod disposed on the output shaft of the tilt drive motor, a support part disposed to the upper left side of the substrate, a rotating connecting block rotatably connected to the support part, and a carrier plate fixedly connected to the rotating connecting block. The right end of the carrier plate is in contact with the top of the swing rod. The mold rocking drive motor is fixed to the upper surface of the carrier plate.

[0012] By controlling the rotation of the tilt drive motor, the swing arm rotates, lifting the right end of the support plate and thus adjusting the angle of the beaker.

[0013] Preferably, the cup tilting unit controls the tilt of the support plate within a range of 1° to 10°.

[0014] Preferably, the range of beaker rotation speed controlled by the mold rocking drive unit is less than 3 revolutions per second.

[0015] Preferably, the beaker clamping unit includes:

[0016] An end block fixed to the side edge of the upper surface of the support plate, a clamping push block that directly clamps and contacts the outer wall of the beaker, and a push spring disposed between the clamping push block and the end block.

[0017] Preferably, the surface of the clamping push block is covered with an elastic cushioning material.

[0018] Preferably, the elastic cushioning material is made of rubber.

[0019] In summary, compared with the prior art, the above-described technical solution conceived by this utility model can achieve the following beneficial effects:

[0020] (1) The present invention provides an auxiliary shaking device for preparing defibrinated blood for acidification hemolysis test. By integrating the cup tilting unit and the shaking drive unit, it solves the technical defects of traditional manual shaking by medical personnel, which is difficult to meet the needs of large-scale operations. In addition, by adding tilting action, it cleverly simulates the technical effect of the internal glass ball rotating along the beaker wall when manually shaking the beaker. Its shaking action amplitude is relatively light and more in line with the characteristics of defibrinated blood preparation. In addition, the tilting angle and rotation speed of the beaker can be controlled, which effectively ensures the technical requirements of shaking speed and shaking action in the preparation process of defibrinated blood, pushes the action towards standardization, and improves the consistency of the test. Attached Figure Description

[0021] Figure 1 This is an initial state diagram of an auxiliary shaking device for preparing defibrinated blood for an acidification hemolysis test according to an embodiment of the present invention.

[0022] Figure 2 This is a diagram illustrating the usage state of an auxiliary shaking device for preparing defibrinated blood in an acidification hemolysis test, according to an embodiment of this utility model.

[0023] In all the accompanying drawings, the same reference numerals denote the same technical features, specifically: 1-balloon, 2-exhaust top umbrella, 1-base assembly, 101-base plate, 102-support leg, 2-cup tilting unit, 200-tilting drive motor, 2001-swing rod, 201-support part, 202-rotating connecting block, 203-bearing plate, 3-mold rocking drive unit, 300-mold rocking drive motor, 301-driving bevel gear, 302-support plate, 303-bevel gear part, 304-driven bevel gear, 305-bearing seat, 306-rotating shaft, 4-beaker clamping unit, 401-end block, 402-push spring, 403-clamping push block, 5-beaker, 6-glass bead. Detailed Implementation

[0024] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0025] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0026] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0027] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only for explaining the present utility model and are not intended to limit the present utility model. Furthermore, the technical features involved in the various embodiments of the present utility model described below can be combined with each other as long as they do not conflict with each other.

[0028] like Figures 1-2 As shown in this embodiment of the invention, the auxiliary shaking device for preparing defibrinated blood for the acidification hemolysis test includes:

[0029] The base assembly 1 is composed of a base plate 101 and a support foot 102; the beaker tilting unit 2 is located above the base assembly 1 for controlling the tilt angle of the beaker; the mold shaking drive unit 3 is located at the output end of the beaker tilting unit 2 for simulating the effect of shaking the beaker by hand; and the beaker clamping unit 4 is located at the output end of the mold shaking drive unit 3 for clamping the beaker.

[0030] The mold rocking drive unit 3 includes a mold rocking drive motor 300 fixedly connected to the output end of the cup tilting unit 2, a driving bevel gear 301 fixedly connected to the output shaft of the mold rocking drive motor 300, a support disk 302 with a bevel tooth portion 303 at the bottom, a driven bevel gear 304 supported and meshed with the bevel tooth portion 303, a bearing seat 305 for positioning the driven bevel gear 304, and a rotating shaft 306 for fixedly connecting the support disk 302 to the output end of the cup tilting unit 2; the bevel tooth portion 303 meshes with the driving bevel gear 301 for transmission.

[0031] The beaker is fixed and clamped by the beaker clamping unit 4, the beaker tilting angle is controlled by the beaker tilting unit 2, and the beaker shaking effect is simulated by the shaking drive unit 3.

[0032] like Figure 1 As shown in this embodiment of the invention, the cup tilting unit 2 includes:

[0033] The system includes a tilt drive motor 200 fixed to the upper right side of the substrate 101, a swing rod 2001 disposed on the output shaft of the tilt drive motor 200, a support portion 201 disposed to the upper left side of the substrate 101, a rotating connecting block 202 rotatably connected to the support portion 201, and a support plate 203 fixedly connected to the rotating connecting block 202. The right end of the support plate 203 is in contact with the swing rod 2001. The mold rocking drive motor 300 is fixed to the upper surface of the support plate 203.

[0034] By controlling the tilt drive motor 200 to rotate, the swing rod 2001 is driven to rotate, which lifts the right end of the support plate 203, thereby adjusting the angle of the beaker.

[0035] like Figure 2 As shown in this embodiment of the utility model, the cup tilting unit 2 controls the tilting range of the support plate 203 to be 1° to 10°.

[0036] like Figure 2 As shown in this embodiment of the invention, the range of the rotation speed of the beaker controlled by the rocking drive unit 3 is less than 3 revolutions per second.

[0037] like Figure 1 As shown, in this embodiment of the present invention, the beaker clamping unit 4 includes:

[0038] The end block 401 is fixed to the side edge of the upper surface of the support plate 302, the clamping push block 403 is in direct contact with the outer wall of the beaker, and the push spring 402 is provided between the clamping push block 403 and the end block 401.

[0039] In this embodiment of the utility model, the surface of the clamping and pushing block 403 is attached with an elastic cushioning material.

[0040] In this embodiment of the invention, the elastic cushioning material is made of rubber.

[0041] Working principle of this utility model:

[0042] S100: First, the beaker to be shaken is clamped and fixed by the clamping push block 403. Under the action of the rubber layer on the surface of the clamping push block 403, wear and damage to the beaker are prevented.

[0043] S200: Next, control the tilt drive motor 200 to rotate, which drives the swing rod 2001 to rotate, lifting the right end of the support plate 203, thereby tilting the components above the support plate 203 and the beaker as a whole, achieving angle adjustment;

[0044] S300: Controls the rotation of the rocking drive motor 300, which drives the active bevel gear 301 to rotate. Under the meshing action, the support plate 302 rotates, thereby achieving the overall tilting rotation of the beaker 5 to simulate the rocking action.

[0045] In this invention, by integrating the beaker tilting unit with the shaking drive unit, the technical shortcomings of traditional manual shaking methods by medical personnel, which are difficult to meet the needs of large-scale operations, are generally solved. Furthermore, by adding a tilting motion, the technical effect of the internal glass ball continuously rotating along the beaker wall when manually shaking the beaker is cleverly simulated. Moreover, the shaking motion is relatively lightweight, which is more in line with the characteristics of defibrinated blood preparation. In addition, the tilting angle and rotation speed of the beaker are controllable, which effectively ensures the technical requirements of shaking speed and shaking motion in the defibrinated blood preparation process, promotes the standardization of the action, and improves the consistency of the experiment.

[0046] The above are merely preferred embodiments of this application and are not intended to limit this application. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the protection scope of this application. The above are merely preferred embodiments of this application. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of this application, and these improvements and modifications should also be considered within the protection scope of this application.

Claims

1. A defibrated blood preparation aid shaker device for acidification hemolysis testing, characterized by, The utility model relates to a kind of simulation shaking cup device, including: Base assembly (1) including by substrate (101) with support leg (102), be used to control beaker inclination angle for being arranged in the base assembly (1) upper cup body inclination unit (2), be arranged in the cup body inclination unit (2) output end for simulating the effect of shaking cup by hand of mode shaking drive unit (3), be arranged in the mode shaking drive unit (3) output end for clamping beaker's beaker clamping unit (4); The mode shaking drive unit (3) includes the mode shaking drive motor (300) fixedly connected with the cup body inclination unit (2) output end, the driving bevel gear (301) fixedly connected with the output shaft of the mode shaking drive motor (300) and kept coaxial, the support disc (302) with the bevel gear portion (303) in bottom, the driven bevel gear (304) transmission connection with the bevel gear portion (303) support engagement, the bearing seat (305) of positioning driven bevel gear (304), the rotating shaft (306) of the support disc (302) fixed shaft connection in the cup body inclination unit (2) output end;The bevel gear portion (303) and driving bevel gear (301) engagement transmission; Through beaker clamping unit (4) to be fixed clamping beaker, through cup body inclination unit (2) control beaker inclination fixed angle, through mode shaking drive unit (3) simulation realizes the effect of shaking cup by hand.

2. A defibrated blood preparation aid shaking device for acidification hemolysis test according to claim 1, characterized in that, The cup body inclination unit (2) includes: The inclination drive motor (200) fixed on the right side above the substrate (101), the swing bar (2001) arranged on the output shaft of the inclination drive motor (200), the support portion (201) arranged on the left side above the substrate (101), the rotary connection block (202) rotationally connected with the support portion (201), the bearing plate (203) fixedly connected with the rotary connection block (202), and the swing bar (2001) top touch connection is arranged at the right end of the bearing plate (203);The mode shaking drive motor (300) is fixed on the upper surface of the bearing plate (203); By controlling the rotation of inclination drive motor (200), swing bar (2001) is rotated, the right end of bearing plate (203) is lifted up, and the angle of beaker is adjusted.

3. A defibrated blood preparation aid shaking device for acidification hemolysis test according to claim 2, characterized in that, The inclination range of the cup body inclination unit (2) is controlled to be 1°-10°.

4. A defibrated blood preparation aid shaking device for acidizing hemolysis test according to claim 1, characterized in that, The rotation speed of the mode shaking drive unit (3) is controlled to be less than 3 revolutions per second.

5. A defibrated blood preparation aid shaking device for acidizing hemolysis test according to claim 1, characterized in that, The beaker clamping unit (4) includes: The end block (401) fixed on the upper surface side edge of the support disc (302), the clamping push block (403) directly clamped in contact with the outer wall of the beaker, the push spring (402) arranged between the clamping push block (403) and the end block (401).

6. A defibrated blood preparation aid shaking device for acidification hemolysis test according to claim 5, characterized in that, The surface of the clamping push block (403) is attached with elastic buffer material.

7. A defibrated blood preparation aid shaking device for acidification hemolysis test according to claim 6, characterized in that, The elastic buffer material is rubber material.

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