Microplate collecting device with temperature control function

Abstract

The utility model discloses a microplate collecting device with a temperature control function, and relates to the technical field of cell sorting, the microplate collecting device comprises a pore plate storage unit and a temperature control unit; the pore plate storage unit comprises a storage base, a heat conduction base and a fixing assembly; the heat conduction base is fixed to the storage base, and one face away from the storage base is provided with hole grooves allowing hole protrusions at the bottom of the microporous plate to be inserted in one-to-one correspondence. The fixing assembly is mounted on the base, is arranged around the heat conduction base and is used for limiting and fixing the microporous plate on the heat conduction base; the temperature control unit is installed on the storage base and provided with a heat exchange face making contact with the heat conduction base. According to the design, the temperature of the microporous plate can be accurately controlled to maintain cell activity, and integrated installation of the temperature control unit, the pore plate storage unit and the microporous plate is also realized, so that mobile control is realized; the technical problems that due to the fact that a hole plate storage structure is fixedly arranged, stability and precision of liquid drop distribution are affected, and design flexibility is affected are effectively solved.

Description

Technical Field

[0001] This application relates to the field of cell sorting technology, and in particular to a microplate collection device with temperature control function. Background Technology

[0002] In recent years, droplet microfluidics technology has developed rapidly, with cell sorting based on it being widely used in biological, chemical, and medical analysis processes. In many scientific experiments or industrial applications, researchers often need to dispense sorted positive or negative droplets into well plates (96-well or 384-well plates), ideally containing only one positive or negative droplet per well, and recording the parameter values ​​(such as fluorescence and absorbance) of each droplet. This facilitates subsequent culture, observation, selection, and related experiments. Therefore, the ability to accurately dispense each droplet into the well plate is crucial for users.

[0003] To ensure accurate distribution of each target droplet into a 96-well / 384-well plate, the outflow time between adjacent droplets often needs to be controlled for a long period, ranging from tens of seconds to several minutes. Therefore, the entire process of distributing all droplets into the 96-well / 384-well plate takes at least 30 minutes. This lengthy droplet distribution process can cause the cells encapsulated within the droplets to lose their viability. To mitigate this risk, some manufacturers have shortened the interval, which naturally affects accuracy. Some manufacturers add a temperature control module to the storage area of ​​the 96-well / 384-well plates; however, this module is fixed inside the equipment, resulting in a fixed storage structure for the plates.

[0004] However, research has revealed that the orifice plate is typically about 120mm long x 80mm wide. To meet the requirement of printing the entire orifice plate, the droplet distribution device must cover the entire orifice plate size during its movement. This leads to a difficult and complex layout of the liquid path. The complex layout affects the stability of the droplet flow and the distribution time. Furthermore, the movement of the droplet distribution device may cause various problems such as liquid splashing, affecting the distribution accuracy. In addition, to ensure convenient loading and unloading of the orifice plate, the orifice plate storage mechanism must be placed in a location easily accessible to the customer. Consequently, the droplet distribution device must also be designed to match the layout of the orifice plate storage device, affecting the design flexibility. Utility Model Content

[0005] In view of this, the purpose of this application is to provide a microplate collection device with temperature control function, which integrates temperature control with the orifice plate storage structure, so as to meet the temperature control requirements and facilitate the realization of mobile control, thereby solving the technical problems that affect the stability and accuracy of droplet distribution and the design flexibility due to the fixed setting of the orifice plate storage structure.

[0006] To achieve the above technical objectives, this application provides a microplate collection device with temperature control function, including a microplate storage unit and a temperature control unit;

[0007] The perforated plate storage unit includes a storage base, a heat-conducting base, and a fixing component;

[0008] The heat-conducting base is fixed to the storage base, and the side away from the storage base is provided with corresponding slots for the protrusions at the bottom of the microporous plate to be inserted.

[0009] The fixing component is installed on the base and arranged around the heat-conducting base, and is used to limit and fix the microporous plate on the heat-conducting base;

[0010] The temperature control unit is installed on the storage base and has a heat exchange surface that contacts the heat-conducting base.

[0011] Furthermore, one side of the storage base is provided with a receiving groove for the heat-conducting base to be placed in.

[0012] Furthermore, the fixing component includes two first limiting members;

[0013] The two first limiting members are fixed on both sides of the receiving groove along the first straight line direction to clamp and fix the microporous plate.

[0014] Furthermore, the side of the first limiting member facing the heat-conducting base is provided with an elastic clamping member that presses against the microporous plate;

[0015] At least one of the first limiting members is connected to the storage base in an adjustable position in the first linear direction, so that the pressing force of the elastic clamping member on the microporous plate is adjustable.

[0016] Furthermore, the first limiting member with adjustable position is provided with oval through holes distributed along the first straight line direction;

[0017] The storage base is provided with a threaded hole that connects to the oval through hole;

[0018] A threaded fastener is inserted through the oblong through hole and connected to the threaded hole, which is used to fasten the first limiting member to the storage base together.

[0019] Furthermore, the fixing component also includes two second limiting members;

[0020] Two second limiting members are respectively fixed on both sides of the receiving groove along a second straight direction perpendicular to the first straight direction, for clamping and fixing the microporous plate in the second straight direction;

[0021] The second limiting member has an avoidance groove on the side facing the heat-conducting base.

[0022] Furthermore, the temperature control unit includes a cooling component, a heat sink, a heat-conducting block, and a temperature sensor;

[0023] The heat-conducting block is embedded in the storage base, and one side of it is in contact with the heat-conducting base through the first heat-conducting medium to form the heat exchange surface;

[0024] The temperature sensor is embedded in the heat-conducting block and is used to detect the temperature of the heat-conducting block;

[0025] The refrigeration component has a cold end face and a hot end face;

[0026] The cold end face is in contact with the other side of the heat-conducting block away from the heat-conducting base through a second heat-conducting medium;

[0027] The hot end face is in contact with the heat dissipation contact surface of the radiator through a third heat-conducting medium;

[0028] A fan is installed on the radiator;

[0029] The radiator is fixed to the storage base on the side away from the heat-conducting base, and clamps and fixes the cooling component and the heat-conducting block between the radiator and the heat-conducting base.

[0030] Furthermore, the cooling component is a Peltier.

[0031] Furthermore, the heat dissipation teeth of the radiator are externally fixed with a bracket;

[0032] The bracket is provided with an air duct opening at the end away from the radiator;

[0033] The fan is installed on the air duct opening.

[0034] Furthermore, a first heat insulation layer is provided between the heat-conducting base and the storage base;

[0035] The first insulation layer is provided with clearance holes to avoid the heat exchange surface;

[0036] The cooling component is surrounded by a second heat insulation layer;

[0037] The storage base is surrounded by a third heat insulation layer.

[0038] Furthermore, the storage unit also includes a perforated plate cover;

[0039] The perforated plate cover is installed on the storage base to cover the microporous plate on the heat-conducting base.

[0040] The perforated plate cover is provided with connecting holes that correspond one-to-one with the collection holes on the microporous plate.

[0041] Furthermore, the perforated plate cover is provided with a first magnetic attraction element;

[0042] The storage base or the fixing component is provided with a second magnetic component that magnetically engages with the first magnetic component.

[0043] Furthermore, it also includes a temperature control adapter circuit board;

[0044] The storage base is equipped with a tray;

[0045] The temperature control adapter circuit board is fixed to the tray, and a clearance gap is formed between the circuit board and the tray.

[0046] The temperature control adapter circuit board is electrically connected to the temperature control unit.

[0047] As can be seen from the above technical solutions, the microporous plate collection device with temperature control function designed in this application has the following beneficial effects:

[0048] The microwell plate is fixed by a heat-conducting base, which then contacts the heat exchange surface of a temperature control unit mounted on the storage base. Heat transfer from the heat exchange surface controls the temperature of the heat-conducting base, thereby controlling the temperature of the microwell plate. This design not only accurately controls the temperature of the microwell plate to maintain cell viability but also integrates the temperature control unit, the well plate storage unit, and the microwell plate, facilitating movement control and effectively solving the technical problems that affect the stability and accuracy of droplet distribution and design flexibility due to the fixed structure of the well plate storage unit. Attached Figure Description

[0049] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0050] Figure 1 This is a first-view perspective perspective view of a microporous plate collection device with temperature control function provided in this application.

[0051] Figure 2 This is a second-view perspective view of a microporous plate collection device with temperature control function provided in this application.

[0052] Figure 3 This is a first-view cross-sectional view of a microporous plate collection device with temperature control function provided in this application;

[0053] Figure 4 This is a second-view cross-sectional view of a microporous plate collection device with temperature control function provided in this application;

[0054] Figure 5 A perspective view of a microporous plate collection device with temperature control function provided in this application, including a perforated plate cover.

[0055] Figure 6 This is a cross-sectional view of a microporous plate collection device with temperature control function provided in this application, including a perforated plate cover.

[0056] In the diagram: 100, perforated plate storage unit; 101, storage base; 1011, receiving groove; 102, fixing component; 103, heat-conducting base; 1031, slot; 200, temperature control unit; 11, first limiting component; 111, elastic clamping component; 112, oval through hole; 113, threaded fastener; 12, second limiting component; 121, clearance groove; 21, temperature sensor; 22, heat-conducting block; 23, cooling component; 24, radiator; 241, bracket; 25, fan; 26, threaded connector; 27, single through screw post; 31, first heat insulation layer; 32, second heat insulation layer; 33, third heat insulation layer; 4, perforated plate cover; 41, connecting hole; 42, first magnetic suction component; 43, second magnetic suction component; 5, temperature control adapter circuit board; 51, clearance gap; 6, tray. Detailed Implementation

[0057] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the embodiments of this application.

[0058] In the description of the embodiments of this application, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing the embodiments of this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the embodiments of this application. In addition, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0059] In the description of the embodiments of this application, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a replaceable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in the embodiments of this application based on the specific circumstances.

[0060] This application discloses a microporous plate collection device with temperature control function.

[0061] Please see Figure 1 One embodiment of a microplate collection device with temperature control function provided in this application includes:

[0062] The perforated plate storage unit 100 and the temperature control unit 200.

[0063] The perforated plate storage unit 100 includes a storage base 101, a heat-conducting base 103, and a fixing component 102.

[0064] The heat-conducting base 103 is fixed to the storage base 101, and the side away from the storage base 101 is provided with corresponding slots 1031 for the hole protrusions at the bottom of the microporous plate (not shown in the figure) to be inserted.

[0065] The heat-conducting base 103 can be fixed to the storage base 101 by screws or other fasteners. Moreover, by setting the slot 1031 to correspond to the hole protrusion at the bottom of the microporous plate, it can better support the microporous plate. More importantly, it can increase the heat conduction area with the microporous plate, so that the temperature control unit 200 can better control the temperature of the microporous plate.

[0066] The microporous plate referred to in this application is a 96-well / 384-well plate; regarding the preparation of the storage base 101, it is designed to be made of a material with low thermal conductivity, specifically POM (polyoxymethylene) material. The thermally conductive base 103, on the other hand, is made of a material with high thermal conductivity, specifically 6063 aluminum alloy.

[0067] The fixing component 102 is installed on the base and is arranged around the heat-conducting base 103. It is used to limit and fix the microporous plate on the heat-conducting base 103, so as to prevent the microporous plate from shifting position and ensure the accuracy of droplet collection.

[0068] The temperature control unit 200 is installed on the storage base 101 and has a heat exchange surface that contacts the heat-conducting base 103.

[0069] The microporous plate collection device with temperature control function designed in this application has the following beneficial effects:

[0070] The microwell plate is fixed by a heat-conducting base 103, which then contacts the heat exchange surface of the temperature control unit 200 mounted on the storage base 101. Heat transfer from the heat exchange surface controls the temperature of the heat-conducting base 103, thereby controlling the temperature of the microwell plate. This design not only accurately controls the temperature of the microwell plate to maintain cell viability but also integrates the temperature control unit 200 with the well plate storage unit 100 and the microwell plate, facilitating movement control and effectively solving the technical problems of affecting droplet distribution stability and accuracy, as well as design flexibility, caused by the fixed setting of the well plate storage structure.

[0071] The above is Embodiment 1 of a microporous plate collection device with temperature control function provided in this application. The following is Embodiment 2 of a microporous plate collection device with temperature control function provided in this application. Please refer to the following for details. Figures 1 to 6 .

[0072] Based on the solution of Embodiment 1 above:

[0073] Furthermore, such as Figure 3 As shown, one side of the storage base 101 is provided with a receiving groove 1011 for the heat-conducting base 103 to be placed in, and the fixing component 102 is arranged around the receiving groove 1011.

[0074] The provided accommodating groove 1011 facilitates the positioning and installation of the heat-conducting base 103, making the installation of the heat-conducting base 103 more convenient. At the same time, the provided accommodating groove 1011 can wrap around the heat-conducting base 103, reducing heat loss from the heat-conducting base 103 and saving energy.

[0075] Furthermore, such as Figure 2 As shown, the design of the fixing component 102 includes two first limiting members 11; the two first limiting members 11 are respectively fixed on both sides of the receiving groove 1011 along the first straight line direction, for clamping and fixing the micro-hole plate.

[0076] Taking the first straight line direction as the left and right direction as an example (the left and right direction can be the length direction or the width direction of the micro-hole plate), then the two first limiting members 11 will clamp and fix the micro-hole plate in the left and right direction.

[0077] Furthermore, such as Figure 2 As shown, the first limiting member 11 has an elastic pressing member 111 that presses against the microporous plate on the side facing the heat-conducting base 103; at least one first limiting member 11 is adjustablely connected to the storage base 101 in the first linear direction so that the pressing force of the elastic pressing member 111 on the microporous plate is adjustable.

[0078] The elastic clamping element 111 can be a spring plunger, the purpose of which is to clamp the microporous plate. At least one of the first limiting elements 11 is designed to be position-adjustable, that is, the clamping force of the elastic clamping element 111 on the microporous plate can be changed by adjusting the position. This design can not only accommodate the clamping of microporous plates of more sizes (better to accommodate the sizes of microporous plates from different manufacturers), but also adjust the degree of clamping according to actual needs, thereby ensuring the user's feel when picking up and putting down the microporous plate.

[0079] The first limiting member 11 of this application has a strip-shaped structure design, and there are two elastic pressing members 111, which are located at both ends near the first limiting member 11. At the same time, the first limiting member 11 can be two adjustable members, and there is no specific limitation.

[0080] Furthermore, such as Figure 2 As shown, the first adjustable limiting member 11 has an oblong through hole 112 distributed along the first straight line direction; the storage base 101 has a threaded hole (not shown in the figure) communicating with the oblong through hole 112; a threaded fastener 113 connecting the threaded hole is provided on the oblong through hole 112 to fasten the first limiting member 11 and the storage base 101 together.

[0081] The adjustment principle is as follows:

[0082] Loosen the threaded fastener 113 to create a gap between the first limiting member 11 and the storage base 101. Then adjust the position of the first limiting member 11. After adjustment, tighten the threaded fastener 113 again and press the first limiting member 11 onto the storage base 101. The threaded fastener 113 can be a screw or bolt, and there are no restrictions on its specific type.

[0083] During the design, two oblong through holes 112 were designed and distributed at both ends of the first limiting member 11. This design makes the position adjustment of the first limiting member 11 more stable and accurate, and at the same time makes the pressure applied to the micro-hole plate more uniform.

[0084] Furthermore, such as Figure 2 As shown, the fixing component 102 also includes two second limiting members 12.

[0085] Two second limiting members 12 are fixed on both sides of the receiving groove 1011 along a second straight direction perpendicular to the first straight direction, for clamping and fixing the micro-hole plate in the second straight direction.

[0086] By adding two second limiting members 12 in the second straight direction, the micro-perforated plate is limited from the second straight direction, thereby increasing the fixing effect of the micro-perforated plate and ensuring the reliable fixing of the micro-perforated plate.

[0087] The second limiting member 12 has a relief groove 121 on the side facing the heat-conducting base 103. The relief groove 121 can avoid structures such as human hands and grippers for picking up and placing micro-perforated plates, making it more convenient to pick up and place micro-perforated plates.

[0088] The first limiting member 11 and the second limiting member 12 in this application are also made of heat insulation material, specifically POM material, to ensure heat insulation performance.

[0089] Furthermore, such as Figure 3 As shown, the design of the temperature control unit 200 includes a cooling component 23, a heat sink 24, a heat-conducting block 22, and a temperature sensor 21.

[0090] The heat-conducting block 22 is embedded in the storage base 101, and one side of it is in contact with the heat-conducting base 103 through the first heat-conducting medium to form a heat exchange surface. Specifically, the heat-conducting block 22 is a metal material with good thermal conductivity, such as 6063 aluminum alloy. It is embedded in the bottom of the storage base 101, and one side extends into the receiving groove and is in contact with the heat-conducting base 103 through the first heat-conducting medium. The first heat-conducting medium can improve the tight connection between the heat-conducting block 22 and the heat-conducting base 103, thereby improving the heat transfer effect. The first heat-conducting medium can be thermal grease.

[0091] Temperature sensor 21 is embedded in heat-conducting block 22 to detect the temperature of heat-conducting block 22. Temperature sensor 21 can be a common temperature probe. By sensing the temperature of heat-conducting block 22, accurate temperature control of heat-conducting block 22 is ensured, thereby accurately controlling the temperature of microporous plate on heat-conducting base 103.

[0092] The cooling component 23 has a cold end face and a hot end face. The cold end face contacts the side of the heat-conducting block 22 away from the heat-conducting base 103 through a first heat-conducting medium, and the hot end face contacts the heat dissipation contact surface of the heat sink 24 through a second heat-conducting medium. A fan 25 is installed on the heat sink 24. The second and third heat-conducting media can also be thermal grease, the purpose of which is to improve the contact tightness and further improve the heat transfer effect.

[0093] The cooling and temperature control principle is as follows: when the fan 25 is turned on, the heat of the heat-conducting base 103 is continuously dissipated by the fan 25 to continuously reduce the temperature of the heat-conducting base 103. By adjusting the power of the fan 25, the heat-conducting base 103 can be maintained within the required temperature range to achieve accurate cooling.

[0094] The heat sink 24 is fixed on the other side of the storage base 101 away from the heat-conducting base 103, and clamps and fixes the cooling component 23 and the heat-conducting block 22 between the heat-conducting base 103. This design makes the overall structure of the temperature control module more compact.

[0095] like Figure 4As shown, the radiator 24 has a mounting through hole, through which a heat-insulating threaded connector 26 (which can be a screw or bolt) passes. A single-through screw post 27 is fixed on the storage base 101. The threaded section of the threaded connector 26 can be screwed into the threaded hole of the single-through screw post 27 to press the radiator 24 onto the storage base 101. In the design, the thickness of the single-through screw post 27 extending out of the storage base 101 should be less than the distance between the end of the mounting through hole away from the storage base 101 and the storage base 101, ensuring that the radiator 24 can be pressed firmly onto the mounting base, thereby pressing the cooling component 23 and the heat-conducting block 22 onto the heat-conducting base 103. The threaded connector 26 and the single-through screw post 27 can be made of POM material.

[0096] Furthermore, the cooling component 23 is preferably designed as a Peltier. Using a Peltier as the cooling component 23 not only has a cooling function but also a heating function. When the equipment is not working, the Peltier is controlled to heat in reverse for a certain period of time, which can evaporate the condensate in the perforated plate storage unit 100, avoiding the accumulation of condensate due to long-term operation and effectively improving the problem of condensate accumulation.

[0097] Furthermore, such as Figure 3 As shown, a bracket 241 (the bracket 241 can be a U-shaped plate structure) is fixed to the heat dissipation fins of the heat sink 24. An air duct is provided at the end of the bracket 241 away from the heat sink 24, and the fan 25 is installed on the air duct.

[0098] It is understood that the heat sink 24 of this application can be a common finned heat sink 24 (such as a CPU heat sink 24), and the mounting bracket 241 is provided to facilitate the installation of the fan 25.

[0099] Furthermore, such as Figure 4 As shown, a first heat insulation layer 31 is provided between the heat-conducting base 103 and the storage base 101. The first heat insulation layer 31 has avoidance holes to avoid the heat exchange surface. This design can prevent heat loss from the heat-conducting base 103 and further enhance the heat insulation performance. The first heat insulation layer 31 is a heat insulation pad structure, which can be made of foamed silicone material, without limitation.

[0100] To prevent condensate from entering the cooling component 23, a second heat insulation layer 32 is wrapped around the cooling component 23. The second heat insulation layer 32 is an EVA insulation cotton material layer, which is fixed on the storage base 101.

[0101] To further improve the heat preservation performance, the storage base 101 is surrounded by a third heat insulation layer 33, which is an EVA heat insulation cotton material layer and is fixed on the storage base 101.

[0102] The design of the first insulation layer 31, the second insulation layer 32 and the third insulation layer 33 not only improves the cooling efficiency of the temperature control unit 200, but also greatly reduces the impact of condensate.

[0103] Furthermore, such as Figure 5 As shown, in order to prevent condensate from entering the microporous plate during the cooling process of the temperature control unit 200, the storage unit also includes a perforated plate cover 4; the perforated plate cover 4 is mounted on the storage base 101 and is used to cover the microporous plate on the heat-conducting base 103; the perforated plate cover 4 is a plastic part, specifically made of ABS+PC material.

[0104] The orifice plate cover plate 4 is provided with a connecting hole 41 that corresponds to the collection hole on the microporous plate to ensure that the collection of droplets on the microporous plate is not affected.

[0105] Furthermore, such as Figure 5 As shown, the perforated plate cover 4 is provided with a first magnetic suction member 42; the storage base 101 or the fixing component 102 is provided with a second magnetic suction member 43 that magnetically engages with the first magnetic suction member 42 (in this application, the second magnetic suction member 43 is designed to be embedded in the fixing component 102, specifically embedded in the first limiting member 11 and / or the second limiting member 12).

[0106] The magnetic design secures the orifice cover 4, making it convenient for users to pick up and put down the orifice cover 4 (easy to operate), and ensuring that the orifice cover 4 is firmly and reliably fixed after it is in place.

[0107] The first magnetic component 42 and the second magnetic component 43 are designed to be magnets, and there are no specific restrictions.

[0108] Furthermore, such as Figure 1 as well as Figure 2 As shown, it also includes a temperature control adapter circuit board 5; a tray 6 is provided on the storage base 101; the temperature control adapter circuit board 5 is fixed on the tray 6, and a clearance gap 51 is formed between the temperature control adapter circuit board 5 and the tray 6.

[0109] The temperature control adapter circuit board 5 is electrically connected to the temperature control unit 200, specifically to the refrigeration component 23 and the temperature sensor 21.

[0110] The microporous plate collection device with temperature control function designed in this application can be applied to a mobile device and moved under the control of the mobile device. The design of the tray 6, with a temperature control adapter circuit board 5 forming a clearance gap 51 with the tray 6, avoids the direct mounting of the connecting wires of the cooling component 23 and the temperature sensor 21 onto the cable chain. The connecting wires of the cooling component 23 and the temperature sensor 21 are connected to the temperature control adapter circuit board 5, while the clearance gap 51 allows the cable chain to pass through, thereby isolating the connecting wires from the cable chain and making the cooling component 23 and the temperature sensor 21 more reliable.

[0111] The above provides a detailed description of a microporous plate collection device with temperature control function provided in this application. For those skilled in the art, there may be changes in the specific implementation method and application scope based on the ideas of the embodiments of this application. Therefore, the content of this specification should not be construed as a limitation of this application.

Claims

1. A microporous plate collection device with temperature control function, characterized in that, Includes an orifice plate storage unit (100) and a temperature control unit (200); The orifice plate storage unit (100) includes a storage base (101), a heat-conducting base (103), and a fixing component (102). The heat-conducting base (103) is fixed to the storage base (101), and the side away from the storage base (101) is provided with a corresponding slot (1031) for the hole protrusion at the bottom of the microporous plate to be inserted. The fixing component (102) is installed on the base and arranged around the heat-conducting base (103) for limiting and fixing the microporous plate on the heat-conducting base (103); The temperature control unit (200) is installed on the storage base (101) and has a heat exchange surface that contacts the heat-conducting base (103).

2. The microporous plate collection device with temperature control function according to claim 1, characterized in that, The storage base (101) has a receiving groove (1011) on one side for the heat-conducting base (103) to be placed in.

3. The microporous plate collection device with temperature control function according to claim 2, characterized in that, The fixing component (102) includes two first limiting members (11); The two first limiting members (11) are fixed on both sides of the receiving groove (1011) along the first straight line direction to clamp and fix the microporous plate.

4. The microporous plate collection device with temperature control function according to claim 3, characterized in that, The first limiting member (11) has an elastic clamping member (111) that presses against the microporous plate on the side facing the heat-conducting base (103). At least one of the first limiting members (11) is connected to the storage base (101) in an adjustable position in the first linear direction, so that the pressing force of the elastic clamping member (111) on the microporous plate is adjustable.

5. A microporous plate collection device with temperature control function according to claim 4, characterized in that, The first limiting member (11) with adjustable position is provided with an oval through hole (112) distributed along the first straight line direction. The storage base (101) is provided with a threaded hole that connects to the oval through hole (112); A threaded fastener (113) is provided on the oblong through hole (112) to connect to the threaded hole, for fastening the first limiting member (11) together with the storage base (101).

6. A microporous plate collection device with temperature control function according to claim 3, characterized in that, The fixing component (102) also includes two second limiting members (12); The two second limiting members (12) are respectively fixed on both sides of the receiving groove (1011) along a second straight direction perpendicular to the first straight direction, for clamping and fixing the microporous plate in the second straight direction; The second limiting member (12) has a relief groove (121) on the side facing the heat-conducting base (103).

7. A microporous plate collection device with temperature control function according to claim 1, characterized in that, The temperature control unit (200) includes a cooling component (23), a heat sink (24), a heat-conducting block (22), and a temperature sensor (21). The heat-conducting block (22) is embedded in the storage base (101), and one side of it is in contact with the heat-conducting base (103) through the first heat-conducting medium to form the heat exchange surface; The temperature sensor (21) is embedded in the heat-conducting block (22) and is used to detect the temperature of the heat-conducting block (22); The refrigeration component (23) has a cold end face and a hot end face; The cold end face is in contact with the other side of the heat-conducting block (22) away from the heat-conducting base (103) through the second heat-conducting medium; The hot end face is in contact with the heat dissipation contact surface of the heat sink (24) through a third heat-conducting medium; A fan (25) is installed on the radiator (24); The radiator (24) is fixed on the storage base (101) away from the heat-conducting base (103) and clamps and fixes the cooling component (23) and the heat-conducting block (22) between the heat-conducting base (103) and the storage base (101).

8. A microporous plate collection device with temperature control function according to claim 7, characterized in that, The refrigeration component (23) is a Peltier.

9. A microporous plate collection device with temperature control function according to claim 7, characterized in that, The heat sink (24) has a bracket (241) fixed to its heat dissipation fins. The bracket (241) has an air duct opening at one end away from the radiator (24); The fan (25) is installed on the air duct opening.

10. A microporous plate collection device with temperature control function according to claim 7, characterized in that, A first heat insulation layer (31) is provided between the heat-conducting base (103) and the storage base (101). The first heat insulation layer (31) is provided with clearance holes to avoid the heat exchange surface; The cooling component (23) is surrounded by a second heat insulation layer (32); The storage base (101) is surrounded by a third heat insulation layer (33).

11. A microporous plate collection device with temperature control function according to claim 1, characterized in that, The storage unit also includes a perforated cover plate (4). The perforated plate cover (4) is mounted on the storage base (101) to cover the microporous plate on the heat-conducting base (103); The perforated plate cover (4) is provided with a connecting hole (41) that corresponds to the collection hole on the microporous plate.

12. A microporous plate collection device with temperature control function according to claim 11, characterized in that, The perforated plate cover (4) is provided with a first magnetic suction element (42); The storage base (101) or the fixing component (102) is provided with a second magnetic member (43) that magnetically engages with the first magnetic member (42).

13. A microporous plate collection device with temperature control function according to claim 1, characterized in that, It also includes a temperature control adapter circuit board (5); The storage base (101) is provided with a tray (6); The temperature control adapter circuit board (5) is fixed on the tray (6) and forms a clearance gap (51) between it and the tray (6). The temperature control adapter circuit board (5) is electrically connected to the temperature control unit (200).

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