Human skin hair follicle microorganism sampling and sample processing device
By designing a magnetic fixation mechanism and observation tools, the adaptability and disinfection problems of existing skin and hair follicle microbial sampling devices have been solved, enabling flexible fixation and efficient disinfection of samples of different shapes and sizes, thus improving sampling accuracy and result reliability.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-28
- Publication Date
- 2026-03-20
AI Technical Summary
Existing skin and hair follicle microbial sampling and sample processing devices are difficult to adapt to samples of different sizes and shapes, and are difficult to completely sterilize, which affects the spread of microorganisms and the accuracy of sampling.
It adopts a magnetic fixing mechanism and sample stage design, combined with detachable fasteners, storage boxes, observation mechanisms and shovels, to fix samples of different shapes and sizes, and facilitates sterilization through magnetic connection.
It enables flexible fixation of samples of different shapes and sizes, improves sampling accuracy and disinfection effect, avoids the influence of microbial growth, and ensures the accuracy and reliability of sampling results.
Smart Images
Figure CN224015658U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of experimental instrument technology, specifically to a device for sampling and processing microorganisms from human skin hair follicles. Background Technology
[0002] Sampling human skin microbiota, especially hair follicle microbiota, can obtain microbial samples deep within the hair follicle, helping scientists to gain a deeper understanding of the microbiota inside the hair follicle and further study the relationship between the distribution of hair follicle microbiota and skin health.
[0003] Existing methods for sampling and processing skin follicle microorganisms mainly include: tape peeling, adsorption sampling, minimally invasive puncture sampling, and tissue biopsy. Tape peeling has the greatest advantages in terms of operability, sample quality, and subject acceptability.
[0004] However, current methods for obtaining samples by peeling off adhesive tape involve fixing the sample using a structure similar to a microscope slide holder, and then using tools such as tweezers and spatulas to collect the sample. Since the location of the hair follicles being sampled varies, the type and size of the adhesive tape used for sampling also differs (e.g., using nasal strips for sampling on the nose, and using pre-cut medical tape for sampling on the forearm). This fixing mechanism is often difficult to adapt to samples of different sizes and shapes. Furthermore, traditional fixing mechanisms such as clamps and related sampling tables have grooves, gaps, and other dead corners. Routine disinfection procedures often cannot prevent the growth of microorganisms in these dead corners, leading to the spread of microorganisms and affecting the accuracy of sampling. Utility Model Content
[0005] To address the shortcomings of existing technologies, this invention provides a human skin hair follicle microbial sampling and sample processing device, which solves the problems that existing microbial sampling and sample processing devices are not easily adaptable to samples of different sizes and shapes and are difficult to completely sterilize.
[0006] To achieve the above objectives, this utility model provides the following technical solution:
[0007] This utility model provides a human skin hair follicle microbial sampling and sample processing device, comprising: a sample stage for placing human hair follicle samples; a fixing mechanism disposed on the sample stage; the fixing mechanism includes: a magnetic plate placed on the sample stage; and a fixing member magnetically connected to the magnetic plate for fixing the sample containing human hair follicle samples.
[0008] In a preferred embodiment, the fastener is a set of sheet-like structures of different lengths, one end of the fastener is spindle-shaped, and the end of the fastener away from the spindle-shaped structure is provided with a protrusion.
[0009] In another preferred embodiment, the fixing member is a plurality of circular truncated cone structures, and the top of the circular truncated cone structure of the fixing member is provided with a protrusion.
[0010] In a more preferred embodiment, the fixing mechanism further comprises a receiving box for receiving the fixing member, and the receiving box is magnetically connected with the sample loading table.
[0011] In an embodiment, the utility model further includes an observation mechanism, which comprises: a base table, the base table being magnetically connected with the sample loading table; and a magnifying glass, the magnifying glass being fixedly connected with the base table through a bellows.
[0012] In a preferred embodiment, the outer surface of the bellows is sleeved with a plastic sheath.
[0013] In a preferred embodiment, the magnifying glass further has a built-in illuminating lamp.
[0014] In a more preferred embodiment, the illuminating lamp is a ring of lamp strips embedded in the outer ring of the magnifying glass.
[0015] In an embodiment, the utility model further includes a spatula, the spatula being magnetically connected with the sample loading table.
[0016] In a preferred embodiment, the blade of the spatula has an arc-shaped horizontal plane.
[0017] In an embodiment, the utility model further includes a tube rack, the tube rack being magnetically connected with the sample loading table.
[0018] In a preferred embodiment, the tube rack is made of a magnetic metal material.
[0019] In a preferred embodiment, the fixing member is made of a non-ferromagnetic material with ferromagnetic material.
[0020] The utility model provides a human skin follicle microorganism sampling and sample processing device.
[0021] Through the setting of the fixing mechanism, the experimental personnel can adjust the position of the fixing member and the contact area of the fixing member and the sample according to different shapes and areas of the sample at any time, so that the sampling is facilitated, the sample loading table can be provided as a smooth structure, the fixing member can be separated, and disinfection treatment is facilitated, so that the growth of other microorganisms is avoided, and the collection accuracy and experimental results are affected. BRIEF DESCRIPTION OF DRAWINGS
[0022] In order to more clearly illustrate the technical solutions of the embodiments of the present application or the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced as follows. Obviously, the drawings in the following description only represent some of the embodiments of the present application, and for those skilled in the art, other drawings can also be obtained without creative labor on the basis of these drawings.
[0023] Figure 1 A human skin follicle microorganism sampling and sample processing device provided by the present application is provided with a three-dimensional schematic view of each component.
[0024] Figure 2 A three-dimensional schematic view of the storage box and the fixing member provided in the embodiments of the present application is provided.
[0025] Figure 3 A three-dimensional schematic view of the observation mechanism provided in the embodiments of the present application is provided.
[0026] Figure 4 A schematic view of the position of the illuminating lamp provided in the embodiments of the present application is provided.
[0027] Figure 5 A three-dimensional schematic view of the spud provided in the embodiments of the present application is provided.
[0028] Figure 6 A schematic view of the detailed structure of the spud blade provided in the embodiments of the present application is provided.
[0029] Figure 7 A three-dimensional schematic view of the pipe support provided in the embodiments of the present application is provided.
[0030] In the drawings: 1, sample loading table; 2, fixing mechanism; 3, observation mechanism; 4, spud; 5, pipe support;
[0031] 21, fixing member; 22, storage box; 31, base table; 32, magnifying glass; 33, illuminating lamp. DETAILED DESCRIPTION
[0032] In order to make the purpose, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions in the embodiments of the present application are described clearly and completely. Obviously, the described embodiments are only some of the embodiments of the present application, but not all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor are within the protection scope of the present application.
[0033] The embodiment of the application provides a human skin follicle microorganism sampling and sample processing device, which comprises a sample loading table used for placing human follicle sampling objects; a fixing mechanism arranged on the sample loading table; the fixing mechanism comprises a magnetic plate arranged on the sample loading table; and a fixing piece magnetically connected with the magnetic plate and used for fixing samples with human follicle sampling objects.
[0034] In order to better understand the above technical solutions, the above technical solutions will be described in detail below in combination with the drawings of the specification and specific embodiments.
[0035] Embodiment 1:
[0036] Referring to Figure 1 As shown in the drawings, the human skin follicle microorganism sampling and sample processing device comprises a sample loading table 1 used for placing human follicle sampling objects; a fixing mechanism 2 arranged on the sample loading table 1; the fixing mechanism 2 comprises a magnetic plate arranged on the sample loading table 1; and a fixing piece 21 magnetically connected with the magnetic plate and used for fixing samples with human follicle sampling objects.
[0037] It should be noted that the sample loading table 1 is arranged to be smooth on the surface, so that disinfection work can be easily performed, and microorganisms in dead corners such as joints and grooves are avoided to affect the accuracy of human follicle microorganism sampling and results; the magnetic plate can be arranged inside the sample loading table 1; the magnetic plate can be a common magnet material, or can be arranged as an electromagnet mechanism, and the magnetic force strength is controlled through a switch and related components; such technology is commonly used in related scenes such as community unit doors, and will not be described here; the fixing piece 21 is detachably connected with the magnetic plate, that is, the sample loading table 1, through the magnetic connection, so that the fixing piece 21 can be fixed according to the size and shape of the sampling adhesive tape at any time, and the fixing piece 21 can also be separately disassembled for disinfection treatment, and the disinfection effect is good.
[0038] Referring to Figure 1 In a preferred embodiment, the fixing piece 21 is a plurality of sheet structures with different lengths, one end of the fixing piece 21 is in a shuttle shape, and the end of the fixing piece 21 away from the shuttle structure is provided with a protrusion.
[0039] It should be noted that the shuttle end part of the fixing piece 21 is used to fix the adhesive tape, and the limiting effect is controlled by controlling the area of the adhesive tape limited between the fixing piece 21 and the sample loading table 1, so that the edge curling of the adhesive tape during sampling is avoided; the protrusion structure can facilitate the experimental personnel to take and disassemble the fixing piece 21.
[0040] Referring toFigure 2 As shown in another preferred embodiment, the fixing member 21 is in a plurality of circular truncated cone structures, and the top of the circular truncated cone structure of the fixing member 21 is provided with a protrusion.
[0041] It should be noted that the fixing member 21 in the circular truncated cone structure has a small volume, and is easy to store and disinfect.
[0042] Referring to Figure 2 As shown in a more preferred embodiment, the fixing mechanism 2 further comprises a storage box 22 for storing the fixing member 21, and the storage box 22 is magnetically connected with the sample loading table 1.
[0043] It should be noted that the storage box 22 is convenient for the experimental personnel to take and store the fixing member 21, and the storage box 22 is magnetically connected with the sample loading table 1, such as being provided with a magnet at the bottom of the storage box 22, which can also be disassembled for disinfection.
[0044] Embodiment 2:
[0045] Referring to Figure 1 and Figure 3 As shown, the human skin hair follicle microbial sampling and sample processing device provided by the utility model comprises the contents in embodiment 1 and the related preferred embodiments, in addition, further comprises observation mechanism 3, observation mechanism 3 includes: base table 31, base table 31 with sample loading table 1 magnetically connected, magnifying glass 32, magnifying glass 32 is fixedly connected with base table 31 through bellows.
[0046] It should be noted that the base table 31 is magnetically connected with the sample loading table 1, such as being provided with a magnet at the bottom of the base table 31, which is convenient for the experimental personnel to fix the magnifying glass 32, can also adjust the bellows as needed, and then adjust the position and orientation of the magnifying glass 32, and can also be disassembled for disinfection; the magnifying glass 32 can facilitate the experimental personnel to quickly and accurately distinguish the content similar to the shape of the human hair follicle on the adhesive tape paper; the experimental personnel can control the angle and position of the magnifying glass 32 through the bellows. The bellows are commonly used in devices such as faucets and table microphones, which will not be described here.
[0047] Referring to Figure 4 As shown in a preferred embodiment, the outer surface of the bellows is sleeved with a plastic sheath.
[0048] It should be noted that the plastic sheath can make the outer surface of the bellows smooth, easy to disinfect and clean, and avoid microbial breeding.
[0049] Referring to Figure 4 As shown in a preferred embodiment, the magnifying glass 32 further internally has an illuminating lamp 33.
[0050] It should be noted that the illuminating lamp 33 can provide light source when the experimenter needs to observe, so that the experimenter can accurately find the content similar to the human hair follicle shape on the adhesive tape, thereby improving the sampling efficiency.
[0051] In a more preferred embodiment, the illuminating lamp is a ring of lamp strips embedded in the outer ring of the magnifying glass.
[0052] It should be noted that the lamp strip type illuminating lamp can provide better illumination range for the experimenter, and reduce the influence of shadow on the sampling process.
[0053] Embodiment 3:
[0054] Referring to Figure 5 The utility model provides a human skin hair follicle microorganism sampling and sample processing device, including the above -mentioned embodiment and the content in related preferred embodiment, in addition, still include spade knife 4, spade knife 4 with sample carrier table 1 magnetic connection.
[0055] It should be noted that the spade knife 4 is used to take down the hair follicle sampling on the adhesive tape, and the spade knife 4 is magnetically connected with the sample carrier table 1, such as setting magnet inside the end for holding of spade knife 4, to facilitate the experimenter to use.
[0056] Referring to Figure 6 In a preferred embodiment, the blade horizontal plane of the spade knife 4 is arc-shaped.
[0057] It should be noted that the blade horizontal plane of the spade knife 4 is arc-shaped, which is beneficial for the experimenter to conveniently and completely take down the hair follicle sampling from the adhesive tape.
[0058] Embodiment 4:
[0059] Referring to Figure 7 The utility model provides a human skin hair follicle microorganism sampling and sample processing device, including the above -mentioned embodiment and the content in related preferred embodiment, in addition, still include pipe support 5, pipe support 5 with sample carrier table 1 magnetic connection.
[0060] It should be noted that the pipe support 5 is magnetically connected with the sample carrier table 1, such as setting magnet in the bottom of the pipe support 5, and the pipe support 5 can fix the centrifugal tube. After the experimenter takes down the hair follicle sampling, the content can be placed in the centrifugal tube in time, so as to avoid the content being polluted by other microorganisms due to the transfer of the hair follicle sampling for a long time, and affect the sampling accuracy and experimental results.
[0061] In a preferred embodiment, the pipe support 5 is made of magnetic metal material.
[0062] It should be noted that the tube rack 5 is placed in a refrigeration device such as a refrigerator for freezing or refrigeration for a period of time before the sampling work is performed, and is placed on the sample loading table 1 during the sampling work, and the experimenter can perform short-term refrigeration through the tube rack when placing the centrifuge tube, thereby protecting the microbial sample.
[0063] In a preferred embodiment, the fixing member 21 is made of a non-ferromagnetic material with a ferromagnetic material.
[0064] It should be noted that the fixing member 21 can be provided with a plastic embedded magnet structure, which is commonly used in blackboards and other devices. The plastic part is convenient for shaping during production. The fixing member 21 is magnetically connected to the magnetic plate through the magnet, that is, it is detachably connected to the sample loading table 1.
[0065] In summary, compared with the prior art, the following beneficial effects are achieved:
[0066] 1. By providing the fixing mechanism (magnetic plate, fixing member, and storage box), the experimenter can adjust the position of the fixing member and the contact area between the fixing member and the sample according to the different shapes and areas of the sample at any time, thereby facilitating the sampling process. Therefore, the sample loading table can be provided with a smooth surface structure, and the fixing member and the storage box can be separated for individual sterilization, which facilitates the sterilization process and avoids the growth of other microorganisms that affect the accuracy of sampling and experimental results. The storage box also facilitates the experimenter to take and store the fixing member.
[0067] 2. By providing the observation mechanism (base, magnifying glass, bellows, and illuminating lamp), the base is fixed by a magnet, which facilitates sterilization and position adjustment. The experimenter can quickly distinguish the content on the adhesive tape that resembles a human hair follicle shape with the help of the magnifying glass and illuminating lamp, thereby improving the efficiency of the sampling work. The experimenter can also adjust the position and angle of the magnifying glass and illuminating lamp through the base and bellows, thereby improving the convenience of sampling.
[0068] 3. By providing the spatula and tube rack, the efficiency of the sampling work is improved. The blade of the spatula is arc-shaped, which makes it easy for the experimenter to remove the hair follicle sample on the adhesive tape. The tube rack can fix the centrifuge tube, so that after the experimenter removes the hair follicle sample, the content can be immediately placed in the centrifuge tube, thereby avoiding the content being exposed to the air for a long time due to the transfer of the hair follicle sample, which can be contaminated by other microorganisms, thereby affecting the sampling accuracy and experimental results.
[0069] It is to be noted that the relational terms herein, such as first and second, and the like, are used solely to distinguish one from another entity or action without necessarily requiring or implying any actual relationship or order between such entities or actions. Moreover, the terms "comprises", "comprising", or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but can also include other elements not expressly listed or inherent to such process, method, article, or apparatus. An element proceeded by "comprises... a" does not, without more constraints, exclude the existence of additional identical elements in the process, method, article, or apparatus that comprises the element.
[0070] The above embodiments are only used to illustrate the technical solutions of the present application, but not limit the present application; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that the technical solutions recorded in the foregoing embodiments can be modified, or some technical features can be replaced by equivalent ones; and these modifications or replacements do not make the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present application.
Claims
1. A device for sampling and processing microorganisms from human skin hair follicles, characterized in that, include: Sample stage (1), used to place human hair follicle samples; A fixing mechanism (2) is provided on the sample carrier stage (1); The fixing mechanism (2) includes: A magnetic plate is placed on the sample stage (1); Fixing member (21), which is magnetically connected to the magnetic plate, is used to fix the sample containing human hair follicle sample.
2. The human skin hair follicle microbial sampling and sample processing device as described in claim 1, characterized in that, The fastener (21) is a set of sheet-like structures of different lengths. One end of the fastener (21) is spindle-shaped, and the end of the fastener (21) away from the spindle-shaped structure has a protrusion.
3. The human skin hair follicle microbial sampling and sample processing device as described in claim 1, characterized in that, The fastener (21) is a multi-frustum structure, and the top of the frustum structure of the fastener (21) is provided with a protrusion.
4. A human skin hair follicle microbial sampling and sample processing device as described in any one of claims 1-3, characterized in that, The fixing mechanism (2) also includes a storage box (22) for storing the fixing component (21), and the storage box (22) is magnetically connected to the sample stage (1).
5. The human skin hair follicle microbial sampling and sample processing device as described in claim 1, characterized in that, The device further includes an observation mechanism (3), which includes: A base platform (31) is magnetically connected to the sample stage (1); A magnifying glass (32) is fixedly connected to the base (31) via a corrugated pipe.
6. The human skin hair follicle microbial sampling and sample processing device as described in claim 5, characterized in that, The magnifying glass (32) also has a built-in light (33).
7. The human skin hair follicle microbial sampling and sample processing device as described in claim 1, characterized in that, The device also includes a shovel (4), which is magnetically connected to the sample stage (1).
8. The human skin hair follicle microbial sampling and sample processing device as described in claim 7, characterized in that, The blade of the shovel (4) has an arc-shaped horizontal surface.
9. The human skin hair follicle microbial sampling and sample processing device as described in claim 1, characterized in that, The device also includes a tube rack (5), which is magnetically connected to the sample stage (1).
10. The human skin hair follicle microbial sampling and sample processing device as described in claim 1, characterized in that, The fastener (21) is made of a non-ferromagnetic material with ferromagnetic material.