High-pressure damper for high performance liquid chromatography system

Abstract

The high-pressure damper comprises a top cover, a base, a sealing piece and a waveform diaphragm, a butt joint groove is formed in the top cover, a liquid inlet and a liquid outlet are formed in the bottom, corresponding to the butt joint groove, of the top cover, the liquid inlet and the liquid outlet are both communicated with the butt joint groove, a buffer groove is formed in the base, and the sealing piece is arranged in the buffer groove. The base is provided with an abutting portion corresponding to an opening of the buffer groove, the base is correspondingly connected with the top cover, the buffer groove is correspondingly communicated with the butt joint groove, the sealing piece is arranged on the abutting portion, and the waveform diaphragm is arranged on the side, away from the abutting portion, of the sealing piece and correspondingly blocks the opening of the buffer groove so that the buffer groove can form a sealed space which is filled with buffer liquid. A gap is reserved between the wave-shaped diaphragm and the groove bottom of the butt joint groove to form a flowing cavity. The device has the advantages that the whole structure is compact, and the occupied space of the device is obviously reduced.

Description

Technical Field

[0001] This utility model relates to the field of mechanical equipment technology, and in particular to a high-pressure damper for a high-performance liquid chromatography system. Background Technology

[0002] In high-performance liquid chromatography (HPLC) analysis, the stability and continuity of the mobile phase are important foundations for ensuring chromatographic peak resolution, retention time reproducibility, and quantitative accuracy. Pressure pulsation is generated by the high-pressure pump during continuous liquid supply.

[0003] In existing technologies, dampers are typically used to reduce flow phase pulsation. Existing dampers generally use buffer diaphragms made of elastic materials. The diaphragms absorb pressure fluctuations through deformation and reduce the flow velocity gradient by relying on the flow channel design. However, the diaphragms are prone to mechanical fatigue and damage under high pressure, which leads to increasingly poor performance.

[0004] Therefore, there is an urgent need to develop a high-pressure damper for high-performance liquid chromatography systems to solve the technical problems encountered in the existing technology. Utility Model Content

[0005] To address the aforementioned technical problems, the purpose of this utility model is to provide a high-pressure damper for a high-performance liquid chromatography system, which can solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides a high-pressure damper for a high-performance liquid chromatography system, comprising:

[0007] The top cover has a docking groove, and the top cover has an inlet and an outlet corresponding to the bottom of the docking groove. Both the inlet and the outlet are connected to the docking groove.

[0008] The base has a buffer groove, and an abutment part is provided on the base corresponding to the opening of the buffer groove. The base is connected to the top cover, and the buffer groove is connected to the docking groove.

[0009] A sealing element, wherein the sealing element is disposed on the abutment portion;

[0010] A waveform diaphragm is disposed on the side of the seal away from the abutment portion and correspondingly blocks the opening of the buffer groove so that the buffer groove forms a sealed space. The sealed space is filled with buffer solution, and a gap is left between the waveform diaphragm and the bottom of the abutment groove to form a flow cavity.

[0011] In some embodiments, the wall of the docking groove is tapered from the opening of the docking groove toward the bottom of the docking groove along its axial direction to form a stepped structure, wherein the width of the cross-section of the step gradually decreases along the depth direction of the docking groove.

[0012] In some embodiments, the bottom of the base has a threaded hole, and a sealing screw is correspondingly provided in the threaded hole.

[0013] In some embodiments, the base and the top cover are threadedly connected.

[0014] In some embodiments, the waveform diaphragm is made of stainless steel.

[0015] Compared with the prior art, the high-pressure damper for high-performance liquid chromatography systems provided by this invention has the following advantages:

[0016] 1. The high-pressure damper for high-performance liquid chromatography system provided by this utility model is directly connected to the buffer groove of the base through the docking groove of the top cover, without the need for additional pipelines or transition parts, which greatly shortens the fluid path, simplifies the assembly process, makes the overall structure of the device compact, and thus significantly reduces the space occupied by the equipment. The simple structure makes the maintenance and repair of the device more convenient. In addition, the corrugated structure of the diaphragm gives it multi-stage elastic deformation capability under pressure pulsation, effectively improving the damping effect and thus meeting more needs.

[0017] 2. The high-pressure damper for high-performance liquid chromatography systems provided by this utility model uses a wavy diaphragm made of stainless steel. Stainless steel has high strength and corrosion resistance, which can provide stronger fatigue resistance, strength and durability, thereby making the damper more practical and reliable. Attached Figure Description

[0018] The preferred embodiments will be described below in a clear and easy-to-understand manner, in conjunction with the accompanying drawings, to further explain the above-mentioned characteristics, technical features, advantages and implementation methods of this utility model.

[0019] Figure 1 This is a three-dimensional schematic diagram of a high-pressure damper for a high-performance liquid chromatography system according to a preferred embodiment of the present invention.

[0020] Figure 2 This is a cross-sectional structural schematic diagram of a high-pressure damper for a high-performance liquid chromatography system according to a preferred embodiment of the present invention.

[0021] Explanation of icon numbers:

[0022] 10 Top cap, 11 Inlet, 12 Outlet, 13 Step, 20 Base, 30 Sealing screw, 40 Seal, 50 Waveform diaphragm, 60 Buffer solution, 70 Flow chamber. Detailed Implementation

[0023] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the specific implementation methods of this utility model will be described below with reference to the accompanying drawings. Obviously, the drawings described below are merely some embodiments of this utility model. For those skilled in the art, other drawings and other implementation methods can be obtained based on these drawings without any creative effort.

[0024] To keep the drawings concise, each figure only schematically shows the parts relevant to the utility model, and these do not represent the actual structure of the product. Furthermore, for ease of understanding, in some figures, only one of the components with the same structure or function is schematically depicted, or only one is labeled. In this document, "one" not only means "only one," but can also mean "more than one."

[0025] It should also be further understood that the term “and / or” as used in this application specification and the appended claims means any combination of one or more of the associated listed items and all possible combinations, and includes such combinations.

[0026] In this document, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to fixed connections, detachable connections, or integral connections; they can refer to mechanical connections or electrical connections; they can refer to direct connections or indirect connections through an intermediate medium; and they can refer to the internal connection between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0027] In one embodiment, refer to the appendix to the specification. Figure 1 and 2The present invention provides a high-pressure damper for a high-performance liquid chromatography system, comprising a top cover 10, a base 20, a sealing element 40, and a corrugated diaphragm 50. The top cover 10 has a docking groove, and an inlet 11 and an outlet 12 are provided on the bottom of the docking groove, both of which are connected to the docking groove. The base 20 has a buffer groove, and an abutment part is provided on the base 20 corresponding to the opening of the buffer groove. The base 20 is connected to the top cover 10, and the buffer groove is connected to the docking groove. The sealing element 40 is provided on the abutment part, and the corrugated diaphragm 50 is provided on the side of the sealing element 40 away from the abutment part, and correspondingly blocks the opening of the buffer groove to form a sealed space. The sealed space is filled with buffer solution 60, and a gap is left between the corrugated diaphragm 50 and the bottom of the docking groove to form a flow cavity 70.

[0028] Specifically, the top cover 10 is provided with an inlet 11 and an outlet 12, both of which are vertically penetrating and communicating with the internal space of the docking groove to form a fluid cavity. Simultaneously, a certain gap is maintained between the bottom of the docking groove and the corrugated diaphragm 50, forming a flow cavity 70. This allows the high-pressure liquid to achieve buffering and pressure reduction through the elastic deformation of the corrugated diaphragm 50 during flow. Additionally, a buffer groove is machined inside the base 20, with an abutment portion at its opening. This abutment portion can be configured as an annular boss or a flange to accommodate the installation of the seal 40 and the fixing of the corrugated diaphragm 50. The top cover 10 and the base 20... The 0 corresponds to precise docking to ensure the sealing of the fluid cavity. In actual operation, the mobile phase flows through the inlet 11 and outlet 12 through the flow cavity 70 formed between the top cover 10 and the corrugated diaphragm 50. At the high point of the mobile phase, the corrugated diaphragm 50 is compressed and deformed, compressing the buffer solution 60, which absorbs the impact of the mobile phase. At the low point of the mobile phase, the buffer solution 60 recovers its volume, thereby pushing the corrugated diaphragm 50 to recover, compensating for the flow and pressure loss of the mobile phase, and thus effectively reducing the pulsation generated by the plunger reciprocating when the external infusion pump is working, thereby ensuring that the pressure and flow rate can be maintained when the mobile phase flows out.

[0029] It should be noted that the seal 40 can be an O-ring, which can be fitted onto the abutment portion to ensure a tight fit with the abutment portion and at the same time ensure that the waveform diaphragm 50 and the buffer solution 60 are in full contact.

[0030] In one embodiment, refer to the appendix to the specification. Figure 1 and 2 Based on the above embodiments, the wall of the docking groove is gradually narrowed from the opening of the docking groove to the bottom of the docking groove along its axial direction to form a stepped structure of step 13. The width of the cross-section of step 13 gradually decreases along the depth direction of the docking groove.

[0031] Specifically, the groove wall of the docking groove gradually narrows axially from the opening end to the bottom of the groove, forming a multi-level stepped platform 13. The number of steps 13 can be three, and the cross-sectional width of each step 13 decreases gradually along the groove depth. The transition surface between steps 13 can be designed as a rounded corner or a bevel. By setting the groove wall as a gradually narrowing step 13, the deformation range of the waveform diaphragm 50 under high pressure is spatially constrained, so that it is only symmetrically compressed along the axial direction, effectively avoiding lateral displacement or local excessive stretching, so that the fluid pressure is evenly applied to the diaphragm surface, rather than concentrated at the groove opening or bottom, thereby effectively avoiding plastic deformation or rupture caused by stress concentration, effectively extending the service life of the damper. In addition, a dynamic compensation mechanism of multi-level sealing contact surface is formed, which can effectively enhance the reliability of the seal and the high pressure resistance.

[0032] In one embodiment, refer to the appendix to the specification. Figure 1 and 2 Based on the above embodiment, the bottom of the groove of the base 20 is provided with a threaded hole, and a sealing screw 30 is correspondingly provided in the threaded hole.

[0033] Specifically, the threaded hole is preferably a fine thread to ensure a tight fit with the sealing screw 30, thereby ensuring the sealing performance of the buffer chamber. The head of the sealing screw 30 can be countersunk and flush with the surface of the base 20 to reduce external interference. In addition, an O-ring can be embedded at the junction of the head of the sealing screw 30 and the threaded section to ensure the reliability of the seal under high pressure. By opening a threaded hole in the base 20, it is convenient to add and replace the buffer solution 60, thereby effectively extending the service life and performance of the damper.

[0034] In one embodiment, the base 20 of the seal 40 is threadedly connected to the top cover 10.

[0035] Specifically, the connecting threads of the base 20 and the top cover 10 are both fine threads to ensure a high-precision fit between the base 20 and the top cover 10, thereby further improving the sealing and reliability of the device and ensuring the practicality of the damper of this application. In addition, the threaded connection facilitates subsequent maintenance and repair.

[0036] In one embodiment, based on the above embodiment, the waveform diaphragm 50 is made of stainless steel.

[0037] Specifically, by setting the waveform diaphragm 50 to a stainless steel material, which has high strength and corrosion resistance, it can provide stronger fatigue resistance, strength and durability, thereby making the damper more practical and reliable.

[0038] It should be noted that the above embodiments can be freely combined as needed. The above are merely preferred embodiments of this utility model. It should be pointed out that for those skilled in the art, several improvements and modifications can be made without departing from the principle of this utility model, and these improvements and modifications should also be considered within the protection scope of this utility model.

Claims

1. A high-pressure damper for a high-performance liquid chromatography system, characterized in that, include: The top cover has a docking groove, and the top cover has an inlet and an outlet corresponding to the bottom of the docking groove. Both the inlet and the outlet are connected to the docking groove. The base has a buffer groove, and an abutment part is provided on the base corresponding to the opening of the buffer groove. The base is connected to the top cover, and the buffer groove is connected to the docking groove. A sealing element, wherein the sealing element is disposed on the abutment portion; A waveform diaphragm is disposed on the side of the seal away from the abutment portion and correspondingly blocks the opening of the buffer groove so that the buffer groove forms a sealed space. The sealed space is filled with buffer solution, and a gap is left between the waveform diaphragm and the bottom of the abutment groove to form a flow cavity.

2. The high-pressure damper for a high-performance liquid chromatography system according to claim 1, characterized in that, The wall of the docking groove gradually narrows from the opening of the docking groove to the bottom of the docking groove along its axial direction to form a stepped structure. The width of the cross-section of the step gradually decreases along the depth direction of the docking groove.

3. The high-pressure damper for a high-performance liquid chromatography system according to claim 2, characterized in that, The base has a threaded hole at the bottom of the groove, and a sealing screw is correspondingly installed in the threaded hole.

4. The high-pressure damper for a high-performance liquid chromatography system according to any one of claims 1-3, characterized in that, The base and the top cover are connected by corresponding threads.

5. The high-pressure damper for a high-performance liquid chromatography system according to claim 4, characterized in that, The waveform diaphragm is made of stainless steel.

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