Pelletizing device for production of pioglitazone and metformin tablets

Abstract

The utility model discloses a granulating device for producing pioglitazone and metformin tablets, and relates to the technical field of medicine production. A top cover is clamped to the top of the raw material box, a first rotating motor is fixedly clamped to the top of the top cover, lifting air cylinders are arranged on the periphery of the bottom of the raw material box, a granulation pressing plate is arranged in the center of the bottom of the raw material box, a cutting knife is slidably clamped to the bottom of the granulation pressing plate, and the net-shaped conveying belt is arranged at the bottom of the raw material box. By arranging the raw material box and the net-shaped conveying belt, the problems that when a cutting knife is used for directly cutting particles, due to the fact that metformin raw materials are high in humidity and viscosity, when the cutting knife is used for directly cutting the particles, a large number of particles are likely to be stacked and bonded and are inconvenient to dry subsequently, and when the cutting knife is too slow, the particles are likely to be attached to the surface of the cutting knife, and the cutting efficiency is poor are solved. And when particles of different sizes need to be extruded, an extrusion plate needs to be replaced, and time and labor are wasted in operation.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the technical field of medicine production, especially, relate to a granulating device for pioglitazone metformin tablet production. BACKGROUND

[0002] Pioglitazone metformin tablet is used as the auxiliary way of diet control and physical exercise, is used for improving the blood sugar control of 2 type diabetes people, is suitable for the patient who is not good at the treatment effect of using metformin hydrochloride alone, and the patient who uses the combined treatment of pioglitazone hydrochloride and metformin hydrochloride, and the pioglitazone metformin tablet needs to be made into granules first after the uniform mixing of raw materials, and then the granules are compressed into tablets after drying, in order to guarantee the clean and neat of the production area and guarantee the production efficiency, usually need to use the granulating device to assist the staff to granulate the pioglitazone metformin tablet, but it still has the following problems in the actual use:

[0003] The utility model discloses a metformin glipizide tablet's granule granulating device of granule, the upper surface middle welding of operation platform has the granule box, the upper surface intercommunication of granule box has the connecting pipe, the upper surface intercommunication of connecting pipe has the mixing box, in the granulating process, cutting knife is after carrying out cutting to raw material, because the moisture of raw material is higher before drying, and has certain viscosity, and cutting too fast can lead to the rapid spatter of granule, and the rapid falling can lead to the accumulation of granule between sticking, and cutting slower can lead to the granule adhesion on the surface of cutting knife, reduce processing efficiency;

[0004] When the mixed raw materials are transported to the granulating structure, only the granules of corresponding size can be pressed according to the particle ejection hole of the extrusion plate, and when the tablets to be made are larger, the extrusion plate needs to be replaced, which is time-consuming and laborious to operate. UTILITY MODEL CONTENTS

[0005] The utility model discloses a granulating device for pioglitazone metformin tablet production, through raw material box and meshy conveyer, the problem that because the moisture of metformin raw material is larger, the viscosity is larger, when cutting too fast can lead to a large amount of granule accumulation sticking, inconvenient for subsequent drying, cutting too slow can lead to the granule adhesion on the surface of cutting knife, and when the granules of different sizes need to be extruded, the extrusion plate needs to be replaced, which is time-consuming and laborious to operate.

[0006] To solve the above technical problems, the utility model is realized by the following technical schemes:

[0007] The utility model discloses a granulating device for pioglitazone metformin tablet production, including raw material box and net conveyer belt, the raw material box top joint has the top cap, the top cap top joint fixedly has the first rotation motor, the raw material box bottom all around is provided with the lift cylinder, the raw material box bottom central part is provided with the granulating pressure plate, the granulating pressure plate bottom sliding joint has the cutting knife, the raw material box bottom is provided with net conveyer belt, one side of net conveyer belt is inserted in the blast engine through,

[0008] Through the first rotation motor can the mixture in the raw material box downward delivery, make raw material extrusion on the surface of granulating pressure plate, and through the granulating hole pressure out the particle of appropriate size, improve the degree of automation of device, through the lift cylinder can adjust the distance between granulating pressure plate and net conveyer belt, when the particle size that needs to press is greater than the granulating hole, through the lift cylinder adjusts the height of raw material box, make the distance between granulating pressure plate and net conveyer belt appropriate, when the extrusion of raw material, the excess raw material will spread to the outside of granulating hole, make the particle of appropriate size and thickness, do not need to replace granulating pressure plate, simple and convenient operation, and the granulating pressure plate distance net conveyer belt is close, falls to the particle on the surface of net conveyer belt can move through the rotation of net conveyer belt, and the particle will not appear deformation and accumulation, cutting knife can be quickly moved to contract to the storage scraper bottom after sliding cutting, scrape off the particle adhered to the bottom of cutting knife, guarantee the integrity of particle, improve production efficiency, when the particle moves to the top of blast engine when moving through the rotation of net conveyer belt, through the flow of hot air driven by blast engine, can carry out the preliminary drying to the surface of particle, avoid the particle adhered to the surface of net conveyer belt, and reduce the time required for subsequent drying, improve processing efficiency.

[0009] Further, the raw material box bottom central part is welded with a feeding pipe, the granulating pressure plate is clamped and fixed at the bottom of the feeding pipe, the raw material box bottom all around is welded and fixed with a telescopic pipe, the lift cylinder is slidingly clamped in the bottom of the telescopic pipe, the telescopic pipe outer circumferential surface is slidingly clamped with a support pipe, and the lift cylinder is clamped in the support pipe.

[0010] Through the lift cylinder, the telescopic pipe can slide along the support pipe, further driving the raw material box to move up and down, adjusting the distance between the granulating pressure plate and the net conveyer belt, when the particle size that needs to be pressed is greater than the granulating hole, the distance between the granulating pressure plate and the net conveyer belt is appropriate, and the excess raw material will spread to the outside of the granulating hole when the raw material is extruded, so that the particles of appropriate size and thickness are made. The granulating pressure plate does not need to be replaced, and the operation is simple and convenient.

[0011] Further, the top cap is welded with a feeding pipe, the first rotation motor is clamped with a rotating rod, the rotating rod is clamped with a spiral conveying assembly, the rotating rod is inserted into the top cap, and the spiral conveying assembly is attached to the inner wall of the raw material box.

[0012] The rotation of the rotating rod and the screw conveying assembly driven by the first rotating motor can further drive the mixed raw materials in the raw material box to be conveyed downward, so that the raw materials are extruded on the surface of the granulating pressing plate, and the particles of appropriate size are pressed out through the granulating holes, thereby improving the automation degree of the device.

[0013] Further, a granulating hole is formed through the top of the granulating pressing plate, and a receiving scraper is fixedly welded to the bottom of the granulating pressing plate, the receiving scraper is located on one side of the granulating hole, the cutting knife is located between the receiving scraper and the granulating pressing plate, a supporting rod is connected to the top of the cutting knife, a cutting cylinder is slidably connected to one end of the supporting rod, the cutting cylinder is connected to the granulating pressing plate, and the cutting cylinder is slidably connected to the inner bottom of the granulating pressing plate.

[0014] After the particles of appropriate size are extruded, the cutting cylinder drives the supporting rod and the cutting knife to slide, cuts the raw materials, and drives the reverse movement of the supporting rod and the cutting knife, so that the cutting knife is received at the bottom of the receiving scraper, the particles adhering to the bottom of the cutting knife are scraped off, the integrity of the particles is ensured, and the production efficiency is improved.

[0015] Further, first supporting frames are connected to both sides of the mesh conveyor belt, rotating rollers are rotatably connected in the first supporting frames, the mesh conveyor belt is attached to the outer circumferential surface of the rotating rollers, second rotating motors are connected through the first supporting frames and the rotating rollers, supporting plates are fixedly welded to one end of the first supporting frames, the supporting plates are attached to the inner top of the mesh conveyor belt, and the granulating pressing plate is suspended on the top of the supporting plates.

[0016] The supporting plates can support the raw materials, so that when the particles with a size larger than the granulating holes are made, the raw materials will not pass through the mesh conveyor belt, the size of the particles is ensured, the second rotating motors can drive the rotation of the mesh conveyor belt, and further drive the movement of the particles on the upper side of the mesh conveyor belt, so as to avoid the stacking and bonding between the subsequently made particles and the previously made particles.

[0017] Further, second supporting frames are fixedly welded to the bottom of the air blower, a ventilation frame is connected to the top of the air blower, a heating buffer plate is fixedly connected in the ventilation frame, the ventilation frame is attached to the inner top of the mesh conveyor belt, and the air blower is located at the other end of the mesh conveyor belt relative to the raw material box.

[0018] When the particles move to the top of the air blower, the air blower drives the flow of air, so that the air enters the ventilation frame, the air is buffer-flowed and heated by the heating buffer plate, the hot air dries the surface of the particles through the mesh conveyor belt, avoids the particles with high viscosity from adhering to the surface of the mesh conveyor belt and being difficult to fall off, and reduces the time required for subsequent drying, thereby improving the processing efficiency.

[0019] The utility model has the advantages of the following:

[0020] The utility model discloses a cutting device for granulating raw materials of pioglitazone metformin tablets, which comprises a raw material box, a cutting knife, a scraping plate and a mesh conveyor belt, wherein the cutting knife is arranged on the raw material box, the scraping plate is arranged on the cutting knife, and the mesh conveyor belt is arranged below the cutting knife.

[0021] The utility model discloses a cutting device for granulating raw materials of pioglitazone metformin tablets, which comprises a raw material box, a cutting knife, a scraping plate and a mesh conveyor belt, wherein the cutting knife is arranged on the raw material box, the scraping plate is arranged on the cutting knife, and the mesh conveyor belt is arranged below the cutting knife. BRIEF DESCRIPTION OF DRAWINGS

[0022] Figure 1 It is the structure effect drawing of the utility model;

[0023] Figure 2 It is the structure drawing of the raw material box of the utility model;

[0024] Figure 3 It is the sectional view of the raw material box of the utility model;

[0025] Figure 4 It is the structure drawing of the granulating pressing plate of the utility model;

[0026] Figure 5 It is the structure drawing of the mesh conveyor belt of the utility model;

[0027] Figure 6 It is the structure drawing of the air blower of the utility model.

[0028] REFERENCE SIGNS:

[0029] 1, raw material box; 101, top cover; 102, first rotating motor; 103, granulating pressing plate; 104, feeding pipe; 105, discharging pipe; 106, telescopic pipe; 107, supporting pipe; 108, lifting cylinder; 109, rotating rod; 110, screw conveying assembly; 111, granulating hole; 112, storage scraper; 113, cutting knife; 114, supporting rod; 115, cutting cylinder; 2, mesh conveyor belt; 201, second rotating motor; 202, air blower; 203, first supporting frame; 204, supporting plate; 205, rotating roller; 206, ventilation frame; 207, heating buffer plate; 208, second supporting frame. DETAILED DESCRIPTION

[0030] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model.

[0031] Please refer to Figures 1-6 The utility model discloses a granulating device for pioglitazone hydrochloride tablet production, including raw material box 1 and mesh conveyor belt 2, raw material box 1 top joint has top cover 101, and top cover 101 top joint fixed first rotating motor 102 has, and raw material box 1 bottom all around is provided with lifting cylinder 108, and raw material box 1 bottom central part is provided with granulating pressing plate 103, and granulating pressing plate 103 bottom sliding joint has cutting knife 113, and raw material box 1 bottom is provided with mesh conveyor belt 2, and one side of mesh conveyor belt 2 is inserted with air blower 202 in the side through,

[0032] The staff makes the size of granule according to the need, controls lifting cylinder 108 and drives raw material box 1 to move to the appropriate height, pours pioglitazone hydrochloride mixed raw material into raw material box 1, is transported to the mixed in raw material box 1 downward by first rotating motor 102, makes raw material extrude on the surface of granulating pressing plate 103, and the granule of appropriate size is pressed out through granulating hole 111, when the size of the granule that needs to be pressed is greater than granulating hole 111, the raw material in the extrusion process, more than the raw material between granulating hole 111 and mesh conveyor belt 2 will spread to the outside of granulating hole 111, and the granule of appropriate size and thickness is made, cutting knife 113 slides and cuts raw material, and is quickly reversely moved and shrinks to the bottom of storage scraper 112, and the granule adhered to the bottom of cutting knife 113 is scraped off, and the granule falls to the surface of mesh conveyor belt 2 and is moved by the rotation of mesh conveyor belt 2, when the granule moves to the top of air blower 202, raw material box 1 presses the granule again, and air blower 202 drives the flow of hot air to preliminarily dry the surface of the granule on the top of air blower 202.

[0033] Among them as Figures 1-3As shown, the bottom of the raw material box 1 is welded with a discharging pipe 105, the discharging plate 103 is fixed on the bottom of the discharging pipe 105, the bottom of the raw material box 1 is welded with an extension pipe 106, the lifting cylinder 108 is slidably fixed in the bottom of the extension pipe 106, the bottom of the extension pipe 106 is slidably fixed with a supporting pipe 107, the bottom of the lifting cylinder 108 is fixed in the supporting pipe 107, the top of the top cover 101 is welded with a feeding pipe 104, the bottom of the first rotating motor 102 is fixed with a rotating rod 109, the outer surface of the rotating rod 109 is fixed with a spiral conveying assembly 110, the rotating rod 109 is inserted into the top of the top cover 101, and the spiral conveying assembly 110 is attached to the inner wall of the raw material box 1.

[0034] Before the granulation of the pioglitazone metformin tablets, according to the size of the granulation required, the lifting cylinder 108 drives the extension pipe 106 to slide along the supporting pipe 107, further drives the raw material box 1 to move up and down, adjusts the distance between the discharging plate 103 and the mesh conveyor belt 2, when the particle size to be made is larger than the discharging hole 111, the distance between the discharging plate 103 and the mesh conveyor belt 2 is the same as the thickness of the required particle, and after the cutting of the particle, the raw material box 1 is controlled to move upwards to avoid affecting the movement of the particle, when the granulation is carried out, the mixed raw material is poured into the raw material box 1 through the feeding pipe 104, the rotation of the rotating rod 109 and the spiral conveying assembly 110 is driven by the first rotating motor 102, so that the raw material is conveyed into the discharging pipe 105 and extruded through the discharging plate 103.

[0035] As shown in the drawings, Figure 1 , 4 As shown, the top of the discharging plate 103 is provided with a discharging hole 111, the bottom of the discharging plate 103 is fixed with a receiving scraper 112, the receiving scraper 112 is located on one side of the discharging hole 111, the cutting knife 113 is located between the receiving scraper 112 and the discharging plate 103, the top of the cutting knife 113 is fixed with a supporting rod 114, one end of the supporting rod 114 is slidably fixed with a cutting cylinder 115, the cutting cylinder 115 is fixed in the discharging plate 103, and the cutting cylinder 115 is slidably fixed in the bottom of the discharging plate 103.

[0036] After the extrusion of the particles with appropriate size, the cutting cylinder 115 drives the supporting rod 114 and the cutting knife 113 to slide, cuts the raw material, and then drives the reverse movement of the supporting rod 114 and the cutting knife 113, so that the cutting knife 113 is received in the bottom of the receiving scraper 112, and the particles adhered to the bottom of the cutting knife 113 are scraped off.

[0037] As shown in the drawings, Figure 1 , 5As shown in FIG. 6, the mesh conveyor belt 2 is clamped on both sides by a first support frame 203, a rotating roller 205 is rotatably clamped in the first support frame 203, the mesh conveyor belt 2 is attached to the outer peripheral surface of the rotating roller 205, a second rotating motor 201 is clamped on one side of the first support frame 203, the second rotating motor 201 is drivingly connected through the first support frame 203 and the rotating roller 205, a support plate 204 is welded and fixed at one end in the first support frame 203, the support plate 204 is attached to the inner top of the mesh conveyor belt 2, the pelletizing pressing plate 103 is suspended on the top of the support plate 204, a second support frame 208 is welded and fixed around the bottom of the air blower 202, a ventilation frame 206 is clamped on the top of the air blower 202, a heating buffer plate 207 is clamped and fixed in the ventilation frame 206, the ventilation frame 206 is attached to the inner top of the mesh conveyor belt 2, and the air blower 202 is located at the other end of the mesh conveyor belt 2 relative to the raw material box 1.

[0038] The support plate 204 supports the raw material, so that when the size of the particles to be made is larger than the pelletizing hole 111, the raw material will not pass through the mesh conveyor belt 2. After the particles fall onto the upper side of the mesh conveyor belt 2, the second rotating motor 201 drives the rotating roller 205 to rotate, further driving the mesh conveyor belt 2 to rotate, so that the particles on the upper side of the mesh conveyor belt 2 move in the direction of rotation of the mesh conveyor belt 2. When the particles move to the top of the air blower 202, the air blower 202 drives the air flow, so that the air enters the ventilation frame 206, the air is slowed down by the heating buffer plate 207, and the air is heated, so that the hot air dries the surface of the particles through the mesh conveyor belt 2, avoiding the adhesion of particles with high viscosity to the surface of the mesh conveyor belt 2 and difficult to fall off, and reducing the time required for subsequent drying.

[0039] The specific working principle of the utility model is: before the granulation of pioglitazone metformin tablets, according to the size of the required granulation, control the lifting cylinder 108 to drive the telescopic pipe 106 to slide along the support pipe 107, further drive the raw material box 1 to move up and down, make the distance between the granulation pressing plate 103 and the mesh conveyor belt 2 same with the thickness of the required granule, pour the mixed raw material into the raw material box 1 through the feeding pipe 104, drive the rotary rod 109 and the rotation of the screw conveying assembly 110 through the first rotary motor 102, make the raw material conveying to the discharge pipe 105 and extrude through the granulation hole 111 of the granulation pressing plate 103, according to the size of the required granule, control the extrusion time, when the size is larger than the granulation hole 111, more than the raw material between the granulation hole 111 and the mesh conveyor belt 2 will diffuse to the outside of the granulation hole 111, make the granule of suitable size, the cutting cylinder 115 drives the support rod 114 and the cutting knife 113 to slide, cut the raw material, further drive the reverse movement of the support rod 114 and the cutting knife 113, make the cutting knife 113 storage to the bottom of the storage scraper 112, scrape the granule adhered to the bottom of the cutting knife 113, at the same time, the lifting cylinder 108 controls the raw material box 1 to move upward by a proper distance, so that the granulation pressing plate 103 will not affect the movement of the granule, the second rotary motor 201 drives the rotary roller 205 to rotate, further drive the mesh conveyor belt 2 to rotate, make the granule on the upper side of the mesh conveyor belt 2 move along the rotation direction of the mesh conveyor belt 2, when the granule moves to the top of the air blower 202, the air blower 202 drives the air flow, make the air enter the ventilation frame 206, slow flow through the heating slow flow plate 207, and heat the air, make the hot air dry the surface of the granule through the mesh conveyor belt 2, avoid the high viscosity granule adhered to the surface of the mesh conveyor belt 2 difficult to fall off, and reduce the required time of subsequent drying.

[0040] The above is only the preferred embodiment of the utility model, and does not limit the utility model, any modification, equivalent replacement, improvement to the technical scheme recorded in the foregoing embodiments, all belong to the protection scope of the utility model.

Claims

1. A granulating device for pioglitazone metformin tablet production, comprising a raw material tank (1) and a mesh conveyor belt (2), characterized in that: The top cap (101) is connected to the top of the raw material box (1), the first rotating motor (102) is connected to the top of the top cap (101), the lifting cylinder (108) is arranged around the bottom of the raw material box (1), the granulating pressing plate (103) is arranged in the center of the bottom of the raw material box (1), the cutting knife (113) is slidably connected to the bottom of the granulating pressing plate (103), the net conveyor belt (2) is arranged at the bottom of the raw material box (1), and the air blower (202) is inserted into one side of the net conveyor belt (2).

2. A granulation device for pioglitazone metformin tablet production according to claim 1, characterized in that: The bottom of the raw material box (1) is provided with a discharging pipe (105), the granulating pressing plate (103) is connected to the bottom of the discharging pipe (105), the telescopic pipe (106) is welded and fixed around the bottom of the raw material box (1), the lifting cylinder (108) is slidably connected to the bottom of the telescopic pipe (106), the supporting pipe (107) is slidably connected to the bottom of the outer circumferential surface of the telescopic pipe (106), and the lifting cylinder (108) is connected to the inside of the supporting pipe (107).

3. The granulation device for pioglitazone metformin tablet production according to claim 1, characterized in that: The top cap (101) is connected to the top of the raw material box (1), the first rotating motor (102) is connected to the top of the top cap (101), the lifting cylinder (108) is arranged around the bottom of the raw material box (1), the granulating pressing plate (103) is arranged in the center of the bottom of the raw material box (1), the cutting knife (113) is slidably connected to the bottom of the granulating pressing plate (103), the net conveyor belt (2) is arranged at the bottom of the raw material box (1), and the air blower (202) is inserted into one side of the net conveyor belt (2).

4. The granulation device for pioglitazone metformin tablet production according to claim 1, characterized in that: The top cap (101) is connected to the top of the raw material box (1), the first rotating motor (102) is connected to the top of the top cap (101), the lifting cylinder (108) is arranged around the bottom of the raw material box (1), the granulating pressing plate (103) is arranged in the center of the bottom of the raw material box (1), the cutting knife (113) is slidably connected to the bottom of the granulating pressing plate (103), the net conveyor belt (2) is arranged at the bottom of the raw material box (1), and the air blower (202) is inserted into one side of the net conveyor belt (2).

5. The granulation device for pioglitazone metformin tablet production according to claim 1, characterized in that: The top cap (101) is connected to the top of the raw material box (1), the first rotating motor (102) is connected to the top of the top cap (101), the lifting cylinder (108) is arranged around the bottom of the raw material box (1), the granulating pressing plate (103) is arranged in the center of the bottom of the raw material box (1), the cutting knife (113) is slidably connected to the bottom of the granulating pressing plate (103), the net conveyor belt (2) is arranged at the bottom of the raw material box (1), and the air blower (202) is inserted into one side of the net conveyor belt (2). The top cap (101) is connected to the top of the raw material box (1), the first rotating motor (102) is connected to the top of the top cap (101), the lifting cylinder (108) is arranged around the bottom of the raw material box (1), the granulating pressing plate (103) is arranged in the center of the bottom of the raw material box (1), the cutting knife (113) is slidably connected to the bottom of the granulating pressing plate (103), the net conveyor belt (2) is arranged at the bottom of the raw material box (1), and the air blower (202) is inserted into one side of the net conveyor belt (2).

6. A granulation device for pioglitazone metformin tablet production according to claim 1, characterized in that: The bottom of the air blower (202) is welded with a second support frame (208) around, the top of the air blower (202) is clamped with a ventilation frame (206), the ventilation frame (206) is clamped with a heating slow flow plate (207) inside, the top of the ventilation frame (206) is pasted to the top inside of the mesh conveyor belt (2), and the air blower (202) is located at the other end of the mesh conveyor belt (2) relative to the raw material box (1).

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