Liquid chromatograph cleaning pipeline valve body

Abstract

The utility model relates to a cleaning pipeline valve body of a liquid chromatograph. The cleaning pipeline valve body comprises an outer pipe and a condensation assembly, a one-way valve allowing external air to enter is arranged at the upper end of an inner cavity of the outer pipe, the inlet end of the condensation assembly communicates with the outer pipe, and the outlet end of the condensation assembly is connected with the collection assembly. The lower end of the outer tube is hermetically connected with a reagent bottle opening, a first pipeline joint is arranged on the side wall of the outer tube, a suction tube is connected to the inner end of the first pipeline joint, and the suction tube is inserted into a reagent bottle and extends into a reagent. The valve body is arranged at a reagent bottle opening of a cleaning agent containing volatile organic reagents to extract the reagents, negative pressure in the reagent bottle and leakage and pollution caused by volatilization of the reagents can be effectively avoided, volatile gas can be recycled after being collected through the condensation assembly and the collection assembly, and waste of the reagents is avoided.

Description

Technical Field

[0001] This utility model relates to the field of liquid chromatograph cleaning technology, specifically to a liquid chromatograph cleaning pipeline valve body. Background Technology

[0002] In the field of liquid chromatography (LC) analysis, system pipeline cleaning is one of the key steps to ensure the accuracy of analytical results and the stable operation of the instrument. Traditional LC systems commonly use volatile organic reagents as cleaning agents for pipeline cleaning. These reagents are widely accepted and used due to their good solubility and cleaning efficiency.

[0003] In existing technologies, conventional cleaning operations involve directly inserting the tubing connected to the liquid chromatograph's suction pump into a reagent bottle containing volatile organic reagents for cleaning. During reagent extraction, as the reagent volume gradually decreases, a large negative pressure is generated if the bottle opening is sealed, making extraction difficult. Therefore, sealing the bottle opening is not feasible in conventional extraction operations. However, without a sealed bottle opening, the evaporating gases can pollute the laboratory environment, posing a potential threat to the health of operators. Furthermore, under high-temperature conditions, the evaporation rate of the reagent accelerates, requiring continuous replenishment to maintain sufficient cleaning effectiveness, thus increasing experimental costs. Utility Model Content

[0004] The technical problem to be solved by this utility model is to provide a cleaning pipeline valve body for a liquid chromatograph, so as to overcome the shortcomings of the prior art.

[0005] The technical solution of this utility model to solve the above-mentioned technical problems is as follows: A liquid chromatograph cleaning pipeline valve body includes an outer tube and a condenser assembly; the upper end of the inner cavity of the outer tube is provided with a one-way valve that allows external air to enter, the inlet end of the condenser assembly is connected to the outer tube, and the outlet end of the condenser assembly is connected to a collection assembly; the lower end of the outer tube is sealed to the mouth of a reagent bottle, and a first pipe joint is provided on the side wall of the outer tube, the inner end of the first pipe joint is connected to a suction tube, and the suction tube is inserted into the reagent bottle and extends into the reagent.

[0006] The beneficial effects of this utility model are as follows: In use, the lower end of the outer tube is connected to the reagent bottle opening, the suction tube is inserted into the reagent bottle and extends into the reagent, the outer end of the first pipe connector is connected to the suction pump pipe of the liquid chromatograph, and then the reagent is drawn by the suction pump of the liquid chromatograph for system pipe cleaning; because a one-way valve allowing external air to enter is provided, air can enter during reagent suction, preventing negative pressure from forming inside the reagent bottle and maintaining normal suction; when in a high-temperature environment, the reagent evaporation rate is greater than the suction rate of the external equipment. When the temperature reaches a certain level, volatile high-pressure gas forms inside the reagent bottle. This gas enters the outer tube, but due to the obstruction of the one-way valve, it cannot escape from the top of the outer tube and can only enter the condenser. After condensation, it is reduced to liquid reagent and flows into the collection component. By placing this valve at the mouth of the reagent bottle containing volatile organic reagents for reagent extraction, negative pressure, reagent leakage, and contamination can be effectively avoided inside the reagent bottle. Furthermore, the volatile gas can be collected and reused through the condenser and collection components, avoiding reagent waste.

[0007] Based on the above technical solution, the present invention can be further improved as follows.

[0008] Furthermore, the condensation assembly includes a spiral condenser tube; an inner tube is installed inside the outer tube, a one-way valve is installed at the upper port of the inner tube, the lower port of the inner tube is connected to the reagent bottle, the inner tube and the outer tube are spaced apart to form a refrigerant chamber, the refrigerant chamber is filled with a cooling medium, a through hole is opened on the side wall of the inner tube, the spiral condenser tube is coiled around the outside of the inner tube, one end of the condenser tube is connected to the through hole, and the other end of the condenser tube is connected to the external receiving assembly through a second pipe joint installed on the side wall of the outer tube.

[0009] Furthermore, the condensation assembly also includes a thermoelectric cooler, a heat sink, and a cooling fan; the cold end of the thermoelectric cooler is positioned close to the refrigerant cavity, the heat sink is attached to the hot end of the thermoelectric cooler, and the cooling fan is positioned towards the heat sink.

[0010] Furthermore, it also includes a filter module, which includes a housing and filter cotton built into the housing, with the lower end of the housing connected to the top of the one-way valve.

[0011] Furthermore, the outer shell is threaded to the upper end of the outer tube.

[0012] Furthermore, the collection components include a drainage tube and a collection bag. Attached Figure Description

[0013] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0014] Figure 2 This is a cross-sectional structural diagram of the present invention.

[0015] The attached diagram lists the components represented by each number as follows:

[0016] 1. Outer pipe; 11. Refrigerant chamber; 2. Condensing assembly; 21. Condensing tube; 22. Semiconductor cooling chip; 23. Heat sink; 24. Cooling fan; 3. One-way valve; 4. Inner pipe; 41. Through hole; 5. Collection assembly; 51. Drainage pipe; 52. Collection bag; 6. Second pipe joint; 7. Filter module; 71. Outer shell; 72. Filter cotton; 8. First pipe joint; 9. Suction pipe. Detailed Implementation

[0017] The principles and features of this utility model are described below with reference to the accompanying drawings. The examples given are only for explaining this utility model and are not intended to limit the scope of this utility model.

[0018] like Figures 1-2 As shown in Example 1, a liquid chromatograph cleaning pipeline valve body includes an outer tube 1 and a condenser assembly 2; the upper end of the inner cavity of the outer tube 1 is provided with a one-way valve 3 that allows external air to enter; the inlet end of the condenser assembly 2 is connected to the outer tube 1, and the outlet end of the condenser assembly 2 is connected to a collection assembly 5; the lower end of the outer tube 1 is sealed to the mouth of a reagent bottle; a first pipe connector 8 is provided on the side wall of the outer tube 1; the inner end of the first pipe connector 8 is connected to a suction tube 9; the suction tube 9 is inserted into the reagent bottle and extends into the reagent.

[0019] In use, connect the lower end of the outer tube 1 to the reagent bottle opening, insert the suction tube 9 into the reagent bottle and extend it into the reagent, connect the outer end of the first pipe connector 8 to the suction pump pipe of the liquid chromatograph, and then use the suction pump of the liquid chromatograph to draw reagents for system pipeline cleaning of the liquid chromatograph; because a one-way valve 3 is provided to allow external air to enter, air can enter during reagent suction, avoiding negative pressure in the reagent bottle and maintaining normal suction; when in a high-temperature environment, the reagent evaporation rate is greater than the suction rate of the external equipment, and air will form inside the reagent bottle. The volatile high-pressure gas enters the outer tube 1. Due to the obstruction of the one-way valve 3, the gas cannot be discharged from the top of the outer tube 14 and can only enter the condenser 2. After condensation, it is reduced to liquid reagent and flows into the collection component 5. By setting this valve at the mouth of the reagent bottle containing the volatile organic reagent for reagent extraction, it can effectively avoid negative pressure in the reagent bottle, reagent leakage and pollution. Moreover, the volatile gas can be collected by the condenser 2 and the collection component 5 and reused, avoiding reagent waste.

[0020] Example 2 is a further improvement based on Example 1, and its details are as follows:

[0021] The condenser assembly 2 includes a spiral condenser tube 21; an inner tube 4 is provided inside the outer tube 1, a one-way valve 3 is provided at the upper port of the inner tube 4, the lower port of the inner tube 4 is connected to the reagent bottle, the inner tube 4 and the outer tube 1 are spaced apart to form a refrigerant chamber 11, the refrigerant chamber 11 is filled with a cooling medium, a through hole 41 is provided on the side wall of the inner tube 4, the spiral condenser tube 21 is coiled around the outside of the inner tube 4, one end of the condenser tube 21 is connected to the through hole 41, and the other end of the condenser tube 21 is connected to the outer tube assembly 5 through a second pipe joint 6 provided on the side wall of the outer tube 1.

[0022] Since the refrigerant chamber 11 is located between the outer tube 1 and the inner tube 4, the refrigerant chamber 11 completely surrounds the inner tube 4. The cooling medium simultaneously cools the inner tube 4. The high-pressure gas that evaporates at high temperature enters the inner tube 4 from the reagent bottle. It first encounters the pre-cooled inner wall of the inner tube 4 for preliminary cooling, and then enters the condenser tube 21 for further cooling, which greatly improves the cooling efficiency. The spiral condenser tube 21 increases the length of the condenser tube and increases the condensation time of the gas, resulting in better condensation effect. In specific implementation, the condenser tube 21 is made of copper tube, which has a better condensation effect.

[0023] Example 3 is a further improvement based on Example 2, and its details are as follows:

[0024] The condensation assembly 2 also includes a thermoelectric cooler 22, a heat sink 23, and a cooling fan 24. The cold end of the thermoelectric cooler 22 is positioned close to the refrigerant chamber 11, the heat sink 23 is attached to the hot end of the thermoelectric cooler 22, and the cooling fan 24 is positioned towards the heat sink 23. By using the thermoelectric cooler 22 to circulate and cool the cooling medium, the condensation effect is greatly improved. The heat sink 23 and the cooling fan 24 dissipate heat from the hot end of the thermoelectric cooler 22, thereby extending the service life of the thermoelectric cooler 22.

[0025] Example 4 is a further improvement based on Example 1, and its details are as follows:

[0026] It also includes a filter module 7, which includes a housing 71 and a filter cotton 72 built into the housing 71. The lower end of the housing 71 is connected to the top of the one-way valve 3. The filter module 7 can filter out dust, impurities, and moisture from the air.

[0027] Example 5 is a further improvement on Example 4, and its details are as follows:

[0028] The outer casing 71 is threaded to the upper end of the outer tube 1. The threaded connection enables the filter module 7 to be detachably connected, facilitating the replacement of the filter module 7.

[0029] Example 6 is a further improvement based on any one of Examples 1 to 5, and its details are as follows:

[0030] The collection component 5 includes a drainage tube 51 and a collection bag 52. It can collect the condensed solution for reuse.

[0031] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A valve body for cleaning pipelines of a liquid chromatograph, characterized in that, It includes an outer tube (1) and a condenser assembly (2); the upper end of the inner cavity of the outer tube (1) is provided with a one-way valve (3) that allows external air to enter; the inlet end of the condenser assembly (2) is connected to the outer tube (1); the outlet end of the condenser assembly (2) is connected to a collection assembly (5); the lower end of the outer tube (1) is sealed to the mouth of the reagent bottle; the side wall of the outer tube (1) is provided with a first pipe joint (8); the inner end of the first pipe joint (8) is connected to a suction tube (9); the suction tube (9) is inserted into the reagent bottle and extends into the reagent.

2. The liquid chromatograph cleaning pipeline valve body according to claim 1, characterized in that, The condensation assembly (2) includes a spiral condenser tube (21); an inner tube (4) is provided inside the outer tube (1), a one-way valve (3) is provided at the upper port of the inner tube (4), the lower port of the inner tube (4) is connected to the reagent bottle, the inner tube (4) and the outer tube (1) are spaced apart to form a refrigerant chamber (11), a cooling medium is injected into the refrigerant chamber (11), a through hole (41) is provided on the side wall of the inner tube (4), the spiral condenser tube (21) is coiled around the outside of the inner tube (4), one end of the condenser tube (21) is connected to the through hole (41), and the other end of the condenser tube (21) is connected to the collection assembly (5) through a second pipe joint (6) provided on the side wall of the outer tube (1).

3. A liquid chromatograph cleaning pipeline valve body according to claim 2, characterized in that, The condensation assembly (2) also includes a thermoelectric cooler (22), a heat sink (23), and a cooling fan (24); the cold end of the thermoelectric cooler (22) is located close to the refrigerant cavity (11), the heat sink (23) is attached to the hot end of the thermoelectric cooler (22), and the cooling fan (24) is located towards the heat sink (23).

4. A liquid chromatograph cleaning pipeline valve body according to claim 1, characterized in that, It also includes a filter module (7), which includes a housing (71) and a filter cotton (72) built into the housing (71), the lower end of the housing (71) being connected to the top of the one-way valve (3).

5. A liquid chromatograph cleaning pipeline valve body according to claim 4, characterized in that, The outer shell (71) is threaded to the upper end of the outer tube (1).

6. A liquid chromatograph cleaning pipeline valve body according to any one of claims 1 to 5, characterized in that, The collection component (5) includes a drainage tube (51) and a collection bag (52).

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