Sample analysis system and redissolving device
By designing an automated reconstitution device, the pollution and safety risks caused by manual operation of reconstitution solutions for lyophilized powder quality control or calibrator products have been resolved, achieving automated, stable, and efficient reconstitution operations.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-11
- Publication Date
- 2026-03-24
AI Technical Summary
In the existing technology, the reconstitution of lyophilized powder quality control products or calibrators requires manual operation, which leads to repeated exposure of the reconstitution solution to air, making it susceptible to contamination. In addition, the operation is inconvenient and poses a risk of needle prick.
A reconstitution device was designed, comprising a shaking mechanism, a capping mechanism, and a puncture mechanism. It automates the placement of sample tubes, capping, and injection of reconstitution solution, avoiding manual operation. The reconstitution solution is injected directly into the sample tube using a puncture needle, and the shaking mechanism mixes the solution. The capping mechanism ensures the stability of the sample tube and the cap.
It achieves automated operation, avoids contamination of reconstitution solution and the risk of needle pricks, improves work efficiency, and ensures the stability and safety of operation.
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Figure CN224035425U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to in-vitro diagnosis technical field, concretely relates to a sample analysis system and reconstitution device. BACKGROUND
[0002] The quality control product or calibration product for in-vitro diagnosis detection is usually saved in freeze-dried powder form, and when using, the reconstitution solution needs to be taken out manually and then injected into the container containing freeze-dried powder, so as to realize reconstitution of freeze-dried powder, and use after mixing. However, this operation mode has obvious defects, and when working, the detection personnel needs to extract the reconstitution solution and then inject it into the container containing freeze-dried powder, the reconstitution solution is exposed to air for multiple times, is easily contaminated by bacteria in the air, and the multiple manual operations are inconvenient to operate, and sometimes the phenomenon of needle puncture of the operator occurs. SUMMARY
[0003] The utility model discloses a sample analysis system and reconstitution device to solve the problem of manual operation and multiple exposure of reconstitution solution to air in the prior art.
[0004] In order to solve the above technical problems, the utility model adopts the following technical scheme:
[0005] A reconstitution device comprises:
[0006] A shaking mechanism is used for placing a sample tube and performing shaking operation.
[0007] A cover mechanism is used for stabilizing the sample tube cap.
[0008] A puncture mechanism is used for injecting reconstitution solution into the sample tube.
[0009] Further, the shaking mechanism comprises a sample tube rack, a first fixed support and a first driving mechanism; the sample tube rack is rotationally installed on the first fixed support; a plurality of insertion slots for placing sample tubes are arranged on the sample tube rack; and the first driving mechanism is drivingly connected to the sample tube rack for driving the sample tube rack to rotate relative to the first fixed support.
[0010] Further, the insertion slots are each provided with an elastic member.
[0011] Further, the reconstitution device further comprises a mounting support, a second fixed support and a second driving mechanism; the second fixed support is provided with a horizontal guide rail; the mounting support is slidingly installed on the horizontal guide rail; the second driving mechanism is drivingly connected to the mounting support for carrying the mounting support to move back and forth along the horizontal guide rail; the cover mechanism and the puncture mechanism are fixedly installed on the mounting support; and the shaking mechanism is installed on the side facing the cover mechanism and the puncture mechanism.
[0012] Further, the puncture mechanism comprises a puncture needle, a fixed block, a lead screw, a vertical guide rail and a third driving mechanism; the puncture needle is fixedly installed on the fixed block; the fixed block is rotationally installed on the lead screw, and one side of the fixed block is slidingly installed on the vertical guide rail through a sliding block; two ends of the lead screw are rotationally installed on a mounting bracket; and the third driving mechanism is transmissionally connected to one end of the lead screw and used for driving the lead screw to rotate.
[0013] Further, the puncture mechanism comprises a puncture needle, a fixed block, a lead screw, a vertical guide rail and a third driving mechanism; the puncture needle is fixedly installed on the fixed block; the fixed block is rotationally installed on the lead screw, and one side of the fixed block is slidingly installed on the vertical guide rail through a sliding block; two ends of the lead screw are rotationally installed on a mounting bracket; and the third driving mechanism is transmissionally connected to one end of the lead screw and used for driving the lead screw to rotate.
[0014] Further, the puncture mechanism comprises a puncture needle, a fixed block, a lead screw, a vertical guide rail and a third driving mechanism; the puncture needle is fixedly installed on the fixed block; the fixed block is rotationally installed on the lead screw, and one side of the fixed block is slidingly installed on the vertical guide rail through a sliding block; two ends of the lead screw are rotationally installed on a mounting bracket; and the third driving mechanism is transmissionally connected to one end of the lead screw and used for driving the lead screw to rotate.
[0015] Further, the puncture mechanism comprises a puncture needle, a fixed block, a lead screw, a vertical guide rail and a third driving mechanism; the puncture needle is fixedly installed on the fixed block; the fixed block is rotationally installed on the lead screw, and one side of the fixed block is slidingly installed on the vertical guide rail through a sliding block; two ends of the lead screw are rotationally installed on a mounting bracket; and the third driving mechanism is transmissionally connected to one end of the lead screw and used for driving the lead screw to rotate.
[0016] A sample analysis system comprises the reconstitution device.
[0017] The reconstitution device has the following advantages:
[0018] The puncture mechanism directly injects the reconstitution solution into the sample tube on the uniform shaking mechanism, thereby avoiding the problem of pollution caused by multiple extraction of the reconstitution solution during manual operation; the sample tube with the injected reconstitution solution is directly shaken by the uniform shaking mechanism, thereby effectively improving the work efficiency and avoiding the inconvenience and the risk of being pricked by a needle caused by manual operation; in addition, the setting of the gland mechanism can fix the sample tube and the cap without deflection, thereby avoiding unstable puncture or the risk of needle breakage. BRIEF DESCRIPTION OF DRAWINGS
[0019] Figure 1 FIG. 1 is a structural diagram of a reconstitution device according to the present application;
[0020] Figure 2 FIG. 2 is an installation diagram of a gland mechanism and a puncture mechanism according to the present application;
[0021] Figure 3 FIG. 3 is a structural diagram of a uniform shaking mechanism according to the present application;
[0022] Figure 4 FIG. 4 is a structural diagram of an elastic member according to the present application;
[0023] Figure 5The utility model discloses a structure diagram of puncture mechanism.
[0024] Figure 6 The utility model discloses a structure diagram of cover mechanism.
[0025] The utility model discloses a structure diagram of puncture mechanism. Specific embodiment
[0026] The technical scheme in the embodiment of the utility model will be described clearly and completely, and obviously, the described embodiment is only a part of the embodiment of the utility model, not all the embodiment. Based on the embodiment in the utility model, all other embodiments obtained by the ordinary skill in the art without making creative labor belong to the range of the utility model protection.
[0027] As Figure 1 , Figure 2 shown, a kind of reconstituting device, including shaking mechanism, for placing sample tube and carrying out shaking operation;Cover mechanism, for stabilizing sample tube cap;Puncture mechanism, for injecting reconstituting solution into sample tube.
[0028] The utility model places sample tube by shaking mechanism, and puncture mechanism directly injects reconstituting solution into sample tube on shaking mechanism, avoids the problem that artificial operation is extracted repeatedly reconstituting solution and causes pollution;Sample tube for injecting reconstituting solution is directly shaken by shaking mechanism, can effectively improve work efficiency, avoids the inconvenience brought by artificial operation and the problem that it is easily pricked by needle, in addition, the setting of cover mechanism can make the sample tube and cap needing to inject reconstituting solution fixed and not deflected, avoid puncture instability or broken needle risk.
[0029] As Figure 3 , Figure 4 shown, shaking mechanism includes sample tube holder 1, first fixed support 2 and first drive mechanism;Sample tube holder 1 is rotatably installed on first fixed support 2, and can be rotated and shaken relative to first fixed support 2;Sample tube holder 1 is provided with a plurality of insertion slots 3 for placing sample tube;First drive mechanism is transmission connected with sample tube holder 1, for driving sample tube holder 1 to rotate and shake relative to first fixed support 2.
[0030] Further, in order to prevent the sample tube from shaking relative to the slot 3 after being placed in the slot 3, an elastic member 4 is arranged in each slot 3. When the sample tube is placed in the slot 3, the elastic member 4 abuts against the wall of the sample tube to prevent the sample tube from shaking. The elastic member 4 can be a conventional elastic gasket, elastic rubber or the like. Since the structure is common, no further description is given here.
[0031] As shown in Figure 1 , the reconstitution device further comprises a mounting bracket 5, a second fixing bracket 6 and a second driving mechanism. The second fixing bracket 6 is provided with a horizontal guide rail 7. The mounting bracket 5 is slidingly mounted on the horizontal guide rail 7. The second driving mechanism is drivingly connected to the mounting bracket 5 for moving the mounting bracket 5 back and forth along the horizontal guide rail 7. The capping mechanism and the piercing mechanism are both fixedly mounted on the mounting bracket 5. The shaking mechanism is mounted on the side facing the capping mechanism and the piercing mechanism.
[0032] The second driving mechanism drives the mounting bracket 5 to move back and forth along the horizontal guide rail 7, thereby driving the capping mechanism and the piercing mechanism mounted on the mounting bracket 5 to move back and forth along the direction of the sample tube rack 1, so as to be capable of capping or / and injecting reconstitution solution to the sample tube in each slot 3.
[0033] As shown in Figure 5 , the piercing mechanism comprises a piercing needle 8, a fixed block 9, a lead screw 10, a vertical guide rail 11 and a third driving mechanism. The piercing needle 8 is fixedly mounted on the fixed block 9. The fixed block 9 is rotatably mounted on the lead screw 10. One side of the fixed block 9 is slidingly mounted on the vertical guide rail 11 through a sliding block. The two ends of the lead screw 10 are rotatably mounted on the mounting bracket 5. The third driving mechanism is drivingly connected to one end of the lead screw 10 to drive the lead screw 10 to rotate, thereby driving the fixed block 9 to rotate up and down along the lead screw 10.
[0034] When it is necessary to inject reconstitution solution to the sample tube, the third driving mechanism drives the lead screw 10 to rotate, thereby driving the fixed block 9 with the piercing needle 8 to move up and down along the vertical guide rail 11. The piercing needle 8 on the fixed block 9 is inserted into the sample tube to inject reconstitution solution to the sample tube.
[0035] As shown in Figure 6 , the capping mechanism comprises a capping motor 12, a buffer block 13, a buffer rod 14, a spring 15, a pressure cap plate 16 and a guide rod 17. The top of the capping motor 12 is fixed with a guide plate 18. The buffer block 13 is fixedly mounted on the output shaft of the capping motor 12 and can move up and down with the capping motor 12. The buffer block 13 is provided with a through hole. The top of the buffer rod 14 is fixedly mounted on the pressure cap plate 16 through the through hole. The spring 15 is mounted on the buffer rod 14, one end of which abuts against the bottom of the buffer block 13 and the other end of which abuts against the bottom of the buffer rod 14. The top of the guide rod 17 is fixedly arranged with the pressure cap plate 16. The guide plate 18 is provided with a guide hole, and the guide rod 17 is slidingly mounted in the guide hole.
[0036] When the cap pressing operation of the sample tube is needed, the buffer block 13 carried by the capping motor 12 moves downward, and the buffer block 13 drives the buffer rod 14 to move downward through the spring 15 abutting between the buffer block 13 and the bottom of the buffer rod 14, and the capping plate 16 can move downward together with the buffer rod 14 since the capping plate 16 is fixedly installed on the top of the buffer rod 14; when the capping plate 16 contacts the sample tube cap, the capping plate 16 and the buffer rod 14 stop moving downward; the capping motor 12 carries the buffer block 13 to continue moving downward and compress the spring 15, thereby providing the downward pressure of the capping plate 16 for keeping the sample tube and the tube cap from being deflected.
[0037] Further, the capping plate 16 is provided with the positioning hole 19, and the puncture needle 8 injects the reconstitution solution into the sample tube after passing through the positioning hole 19, thereby avoiding the risk of unstable puncture or broken needle.
[0038] Further, the reconstitution device further comprises the cleaning pool 20 for cleaning the puncture needle 8, thereby preventing the cross contamination between the quality control products or calibration products in different sample tubes when the puncture needle 8 is inserted into the different sample tubes.
[0039] Further, the first driving mechanism, the second driving mechanism and the third driving mechanism of the utility model are all composed of the conventional rotary motor, the transmission belt, the driving wheel and the transmission wheel; the transmission belt is driven by the rotary motor to rotate between the driving wheel and the transmission wheel, thereby driving the linear motion of the structure on the transmission belt or the rotary motion of the connecting structure on the transmission wheel; since the structure is relatively common, the details are not described herein.
[0040] Further, the utility model discloses a kind of sample analysis systems, comprising the reconstitution device described above.
[0041] Working principle: sample tube is placed into slot 3, second driving mechanism drives puncture mechanism on mounting bracket 5 to move from cleaning pool 20 to the sample tube of slot 3, capping motor 12 drives buffer block 13 to slowly press down, drive capping plate 16 to press on sample tube cap, buffer block 13 continues to press down at this time, until drive in place, spring on buffer block 13 is in compressed state to provide the pressure on capping plate 16, so that sample tube and tube cap cannot be deflected;Third driving mechanism drives screw rod 10 to rotate, puncture needle 8 passes through sample tube cap along positioning hole 19 on capping plate 16, and reconstitution solution is injected into sample tube.In sufficient quantity, reverse drive screw rod 10 to rotate, and puncture needle 8 is pulled out from sample tube until in-place sensor stops;Second driving mechanism drives puncture mechanism to move to cleaning pool 20, and puncture needle 8 enters cleaning pool 20, to complete the cleaning of puncture needle 8;First driving mechanism drives sample tube rack 1 to swing back and forth, so that the solution in sample tube is mixed uniformly after fusion, and then sample tube is taken out and enters other subsequent processing procedure.
[0042] The above are only embodiments of the present application and are not used to limit the present application, and any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application are included in the claim range of the present application.
Claims
1. A reconstitution device, characterized in that, The utility model relates to a reconstitution device for reconstituting a sample tube, comprising: a shaking mechanism for placing a sample tube and performing a shaking operation; a capping mechanism for stabilizing a sample tube cap; a puncturing mechanism for injecting a reconstitution solution into a sample tube; the capping mechanism comprises a capping motor, a buffer block, a buffer rod, a spring, a cap plate, and a guide rod; a guide plate is fixed on the top of the capping motor; the buffer block is fixedly installed on the output shaft of the capping motor; a through hole is arranged on the buffer block; the top of the buffer rod is fixedly installed on the cap plate through the through hole; the spring is installed on the buffer rod, one end of which is in abutment with the bottom of the buffer block, and the other end of which is in abutment with the bottom of the buffer rod; the top of the guide rod is fixedly connected with the cap plate; a guide hole is arranged on the guide plate, and the guide rod is slidingly installed in the guide hole.
2. A reconstitution device according to claim 1, wherein the shaking mechanism comprises a sample tube rack, a first fixed support, and a first driving mechanism; the sample tube rack is rotationally installed on the first fixed support; a plurality of insertion slots for placing sample tubes are arranged on the sample tube rack; the first driving mechanism is drivingly connected with the sample tube rack for driving the sample tube rack to rotate relative to the first fixed support.
3. A reconstitution device according to claim 2, wherein An elastic member is arranged in each insertion slot.
4. The reconstitution device of claim 1, wherein The utility model further comprises a mounting support, a second fixed support, and a second driving mechanism; a horizontal guide rail is arranged on the second fixed support; the mounting support is slidingly installed on the horizontal guide rail; the second driving mechanism is drivingly connected with the mounting support for carrying the mounting support to move back and forth along the horizontal guide rail; the capping mechanism and the puncturing mechanism are fixedly installed on the mounting support; the shaking mechanism is installed on the side facing the capping mechanism and the puncturing mechanism.
5. A reconstitution device according to claim 4, wherein the puncturing mechanism comprises a puncturing needle, a fixed block, a lead screw, a vertical guide rail, and a third driving mechanism; the puncturing needle is fixedly installed on the fixed block; the fixed block is rotationally installed on the lead screw, and one side of the fixed block is slidingly installed on the vertical guide rail through a sliding block; both ends of the lead screw are rotationally installed on the mounting support; the third driving mechanism is drivingly connected with one end of the lead screw for driving the lead screw to rotate.
6. A reconstitution device according to claim 5, wherein the needle is arranged to pierce the seal when the device is in the first position. The utility model further comprises a cleaning pool for cleaning the puncturing needle.
7. The reconstitution device of claim 1, wherein a positioning hole is arranged on the cap plate.
8. A sample analysis system, characterized by, The utility model further comprises the reconstitution device according to any one of claims 1-7.