Multipurpose sample clamp

Abstract

The utility model relates to the technical field of living cell observation, in particular to a multipurpose sample clamp. A multipurpose sample clamp comprises a positioning frame and a transition groove, and the transition groove is detachably installed in the positioning frame. A clamping mechanism is arranged around one corner of the positioning frame and is used for clamping and fixing a perforated plate or a transition groove; the middle of the transition groove is hollowed out, a sliding shifting piece connected with the transition groove in a sliding mode is arranged in the transition groove, the sliding shifting piece moves in the length direction of the transition groove, a clamping area is formed by the sliding shifting piece and one side of the width of the transition groove, and the clamping area is used for clamping a glass slide or a culture dish. The microscope objective table can be driven to move through the moving platform, different samples can be adapted by replacing the transition groove or the perforated plate, the samples can be kept in direct contact with the objective table through the overall bottom hollowed-out design, and interference to focusing of a microscope is effectively avoided.

Description

Technical Field

[0001] This utility model relates to the field of live cell observation technology, specifically to a multi-purpose sample holder. Background Technology

[0002] In the field of live cell observation, live cell imaging systems are commonly used equipment for real-time observation and recording of the morphology, structure, and physiological activities of live cells. Microscopes with fixed stages typically rely on manual sample movement, which suffers from low operational precision, easy sample damage, and low efficiency.

[0003] Existing modification solutions (such as motorized displacement stages) require disruption of the equipment structure or obstruction of the optical path. Improvements using external motion platforms to drive sample movement also suffer from incompatibility issues with various sample carriers, such as multi-well plates, glass slides, and petri dishes. Furthermore, traditional fixtures, due to structural limitations, may cause samples to become suspended or out of focus.

[0004] Therefore, there is an urgent need for a multi-purpose sample holder to solve the above problems. Utility Model Content

[0005] This utility model addresses the technical problems existing in the prior art by providing a multi-purpose sample clamp that can accurately clamp multiple sample types, maintain direct contact between the sample and the stage, and is compatible with a motion platform to drive its movement.

[0006] The technical solution of this utility model to solve the above-mentioned technical problems is as follows: a multi-purpose sample clamp, including a positioning frame and a transition groove, wherein the transition groove is detachably installed in the positioning frame;

[0007] A clamping mechanism is provided around one corner of the positioning frame, and the clamping mechanism is used to clamp and fix the perforated plate or transition groove.

[0008] The transition groove is hollowed out in the middle, and a sliding paddle is provided in the transition groove and slidably connected thereto. The sliding paddle moves along the length of the transition groove, and the sliding paddle and one side of the width of the transition groove form a clamping area, which is used to clamp a glass slide or culture dish.

[0009] Based on the above technical solution, the present invention can be further improved as follows.

[0010] Furthermore, the sliding paddle has an arc-shaped edge facing the clamping area, with its opening facing the clamping area. A square platform matching the shape of one end of the glass slide is provided in the middle of the arc. The edge shape of the transition groove located in the clamping area is centrally symmetrical with the edge shape of the sliding paddle facing the clamping area.

[0011] Furthermore, the transition groove is provided with two parallel sliding grooves, and a slider is provided in each sliding groove for sliding connection. The sliding paddle is provided with an opening at each end and also includes a screw, one end of which passes through the opening and connects to the slider.

[0012] Furthermore, the clamping mechanism is a rotatable spring clip, which generates a diagonal thrust by rotating, causing the perforated plate or transition groove to fit tightly against the inner side of the positioning frame diagonally opposite the spring clip.

[0013] Furthermore, the inner wall of the positioning frame is provided with an annular platform, which together with the inner wall of the positioning frame forms a positioning area. The outer edge of the perforated plate forms a clearance fit with the positioning area, and the outer edge of the transition groove has the same shape and size as the outer edge of the perforated plate.

[0014] Furthermore, the spring clip is located at the upper right corner of the positioning frame, the rotation axis of the spring clip is perpendicular to the bottom surface of the positioning frame, and a buffer pad is provided at the end of the spring clip.

[0015] Furthermore, it also includes a connecting plate, which is fixedly connected to one corner of the positioning frame.

[0016] Furthermore, the surface of the positioning frame is treated with fluorine plating or sandblasting to form a friction-reducing layer.

[0017] The beneficial effects of this utility model are:

[0018] 1. This utility model uses a combination design of positioning frame and detachable transition groove to be compatible with the clamping of multi-well plate, glass slide and culture dish; sliding paddle forms an adjustable clamping area to adapt to samples of different sizes, and the hollow structure ensures that the sample is in direct contact with the stage to avoid defocusing.

[0019] 2. This utility model features a sliding paddle with a rounded edge and a square platform. The rounded edge is adapted to the shape of the culture dish, and the square platform is adapted to the glass slide. The adjustable clamping area can hold both the glass slide and the culture dish. The symmetrical clamping surface evenly distributes pressure to clamp the sample and prevent sample displacement or damage. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the structure of the multi-purpose sample holder for mounting glass slides according to an embodiment of the present invention.

[0021] The attached diagram lists the components represented by each number as follows:

[0022] 41. Positioning frame; 42. Connecting plate; 411. Spring clip; 412. Transition groove; 413. Sliding paddle; 414. Screw; 415. Slide groove; 416. Clamping area. Detailed Implementation

[0023] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0024] In the description of this application, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the stated features. In the description of this application, "multiple" means two or more, unless otherwise explicitly specified.

[0025] In the description of this application, the term "for example" is used to mean "used as an example, illustration, or description." Any embodiment described as "for example" in this application is not necessarily to be construed as being more preferred or advantageous than other embodiments. The following description is provided to enable any person skilled in the art to implement and use the present invention. Details are set forth in the following description for purposes of explanation. It should be understood that those skilled in the art will recognize that the present invention can be implemented without using these specific details. In other instances, well-known structures and processes will not be described in detail to avoid obscuring the description of the present invention with unnecessary detail. Therefore, the present invention is not intended to be limited to the embodiments shown, but is consistent with the broadest scope of the principles and features disclosed in this application.

[0026] Example

[0027] A multi-purpose sample holder 4 includes a positioning frame 41 and a transition groove 412. The transition groove 412 is detachably installed within the positioning frame 41. A connecting plate 42 provides a rigid connection between the holder and the motion component, ensuring the transmission of motion accuracy to the sample. A clamping mechanism, a rotatable spring clip 411, is provided around the upper right corner of the positioning frame 41. The rotation axis of the spring clip 411 is perpendicular to the bottom surface of the positioning frame 41. A buffer pad is provided at the end of the spring clip 411. The spring clip 411 generates a diagonal thrust through rotation, causing a perforated plate or the transition groove 412 to fit tightly against the inner side of the positioning frame 41 diagonally opposite the spring clip 411, achieving rapid fixing and release and reducing human intervention errors. The clamping mechanism allows for the selection of either a perforated plate or the transition groove 412 to accommodate different samples.

[0028] The positioning frame 41 has a fluorine-plated or sandblasted surface to form a friction-reducing layer, which reduces the friction between the positioning frame 41 and the perforated plate or transition groove 412, making it easier to place and remove, while avoiding scratches; a connecting plate 42 is connected to one corner of the positioning frame 41.

[0029] In a preferred embodiment, the transition groove 412 is hollowed out in the middle, and a sliding paddle 413 is provided in the transition groove 412 and slidably connected thereto. The sliding paddle 413 moves along the length direction of the transition groove 412, and the sliding paddle 413 and one side of the width of the transition groove 412 form a clamping area 416, which is used to clamp a glass slide or a culture dish.

[0030] The sliding paddle 413, facing the clamping area 416, has an arc-shaped edge with its opening facing the clamping area 416. A square platform, matching the shape of one end of the glass slide, is located at the middle of this arc. The edge of the transition groove 412, located on one side of the clamping area 416, is centrally symmetrical to the edge of the sliding paddle 413 facing the clamping area 416. The arc-shaped edge adapts to the shape of the culture dish, and the square platform adapts to the glass slide.

[0031] The transition groove 412 has two parallel sliding grooves 415, each containing a slider that is slidably connected to it. The sliding paddle 413 has an opening at each end and also includes a screw 414, one end of which passes through the opening and connects to the slider. The double sliding grooves 415 and slider structure enhance the stability of the sliding paddle 413, while the screw 414 allows for fine-tuning of the clamping force, ensuring secure clamping and convenient operation.

[0032] In a preferred embodiment, the inner wall of the positioning frame 41 is provided with an annular platform, which together with the inner wall of the positioning frame 41 forms a positioning area. The outer edge of the perforated plate forms a clearance fit with the positioning area, and the outer edge of the transition groove 412 has the same shape and size as the outer edge of the perforated plate. The annular platform and clearance fit design ensure accurate positioning of the perforated plate or the transition groove 412.

[0033] The working process of this utility model is as follows:

[0034] Perforated plate clamping: Remove the transition groove 412, place the perforated plate into the positioning frame 41, and rotate the spring clamp 411 to press it diagonally;

[0035] Slide or petri dish clamping: Place the slide or petri dish into the clamping area 416 of the transition groove 412, slide the lever 413 to adjust it to fit the sample, and tighten the screw 414 with the nut to fix it; then place the entire transition groove 412 into the positioning frame 41 and lock it with the spring clip 411.

[0036] Finally, the positioning frame 41 is connected to the motion component via the connecting plate 42 to realize sample movement. In summary, this utility model achieves precise sample positioning by cooperating with the diagonal thrust of the spring clip 411 through the reference surface inside the positioning frame 41, ensuring no sample offset; by replacing the transition groove 412 or the perforated plate to adapt to different samples, the overall hollow bottom design can effectively avoid focusing of the interference microscope.

[0037] While embodiments or examples of this disclosure have been described with reference to the accompanying drawings, it should be understood that the methods, systems, and devices described above are merely exemplary embodiments or examples, and the scope of this utility model is not limited by these embodiments or examples, but only by the granted claims and their equivalents. Various elements in the embodiments or examples may be omitted or replaced by their equivalents. Furthermore, the steps may be performed in a different order than that described in this disclosure. Further, various elements in the embodiments or examples may be combined in various ways. Importantly, as technology evolves, many elements described herein can be replaced by equivalents that appear after this disclosure.

Claims

1. A multi-purpose sample holder, characterized in that, It includes a positioning frame and a transition groove, wherein the transition groove is detachably installed within the positioning frame; A clamping mechanism is provided around one corner of the positioning frame, and the clamping mechanism is used to clamp and fix the perforated plate or transition groove. The transition groove is hollowed out in the middle, and a sliding paddle is provided in the transition groove and slidably connected thereto. The sliding paddle moves along the length of the transition groove, and the sliding paddle and one side of the width of the transition groove form a clamping area, which is used to clamp a glass slide or culture dish.

2. The multipurpose sample holder of claim 1, wherein, The sliding paddle faces the clamping area, and its edge is arc-shaped with its opening facing the clamping area. A square platform matching the shape of one end of the glass slide is provided in the middle of the arc. The edge shape of the transition groove located in the clamping area is centrally symmetrical with the edge shape of the sliding paddle facing the clamping area.

3. The multipurpose sample holder of claim 1, wherein, The transition groove has two parallel sliding grooves, and a slider is slidably connected to each of the sliding grooves. The sliding paddle has an opening at each end and also includes a screw. One end of the screw passes through the opening and connects to the slider.

4. The multipurpose sample holder of claim 1, wherein, The clamping mechanism is a rotatable spring clip. The spring clip generates a diagonal thrust by rotating, causing the perforated plate or transition groove to fit tightly against the inner side of the positioning frame at the opposite corner of the spring clip.

5. The multipurpose sample holder of claim 4, wherein, The inner wall of the positioning frame is provided with an annular platform, which together with the inner wall of the positioning frame forms a positioning area. The outer edge of the perforated plate forms a clearance fit with the positioning area, and the outer edge of the transition groove has the same shape and size as the outer edge of the perforated plate.

6. The multipurpose sample holder of claim 5, wherein, The spring clip is located at the upper right corner of the positioning frame, the rotation axis of the spring clip is perpendicular to the bottom surface of the positioning frame, and a buffer pad is provided at the end of the spring clip.

7. The multipurpose sample holder of claim 1, wherein, It also includes a connecting plate, which is fixedly connected to one corner of the positioning frame.

8. The multipurpose sample holder of claim 1, wherein, The surface of the positioning frame is treated with fluorine plating or sandblasting to form a friction-reducing layer.

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