Gas-liquid separation and purification device for sterile drug production
By using a threaded auxiliary cooling cylinder and a removable sealing cover design, the problems of reduced condensation effect and non-removable components in aseptic drug production equipment at high temperatures are solved, thus achieving convenient temperature control and component cleaning.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- NANJING SHIFENG BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-04-16
- Publication Date
- 2026-04-21
AI Technical Summary
Existing gas-liquid separation and purification devices for sterile drug production suffer from reduced condensation efficiency as temperatures rise, and are welded and sealed, making it impossible to disassemble and clean internal components.
A detachable gas-liquid separator was designed, which uses a threaded connection to install an auxiliary cooling cylinder and a detachable sealing cover, enabling temperature control and cleaning of internal components.
It achieves gas-liquid separation and condensation at high temperatures, and facilitates the disassembly and cleaning of internal components, thereby improving the efficiency and maintainability of the device.
Smart Images

Figure CN224141805U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of medical device technology, and in particular relates to a gas-liquid separation and purification device for sterile drug production. Background Technology
[0002] A gas-liquid separation and purification device is used in the pharmaceutical production process to separate and recover liquid droplets entrained in secondary steam. It prevents droplets from escaping with the secondary steam through physical methods, thereby ensuring the purity of the production environment. At the same time, it removes microorganisms from liquids or gases through physical methods to meet the quality requirements of sterile drugs. This device is widely used in pharmaceuticals and biological products.
[0003] Based on the above, the inventors have discovered the following shortcomings in existing gas-liquid separation and purification devices for sterile drug production:
[0004] 1. As the temperature rises, the gas-liquid separation and condensation effect of the device gradually decreases, making it inconvenient to install auxiliary measures on the device to keep it at the required temperature.
[0005] 2. The device is a welded and enclosed type, which makes it impossible to clean and replace the internal components. It is inconvenient to add sealing measures to the device so that it can be disassembled for cleaning and replacement of components. Utility Model Content
[0006] To address the aforementioned technical problems, this utility model provides a gas-liquid separation and purification device for sterile pharmaceutical production. This addresses the issues that existing devices experience a gradual decrease in gas-liquid separation and condensation efficiency as temperature rises, making it inconvenient to add auxiliary measures to maintain the device at the required temperature. Furthermore, the device is welded and enclosed, making it impossible to clean and replace internal components, and it is inconvenient to add sealing measures to allow for disassembly and cleaning of components.
[0007] The purpose and effectiveness of this gas-liquid separation and purification device for sterile drug production are achieved through the following specific technical means:
[0008] A gas-liquid separation and purification device for sterile drug production includes a device body; the device body is provided with a gas-liquid separation tank in a vertical direction, a threaded cylinder extending vertically through the center of the bottom wall of the gas-liquid separation tank, a threaded annular groove on the outer circumference of the lower part of the gas-liquid separation tank, a threaded assembly annular groove on the inner circumference of the upper end of the gas-liquid separation tank, a left-right through inlet cylinder on the outer side of the upper end of the left side wall of the gas-liquid separation tank, an annular plate with mounting holes on the outer circumference of the left end of the inlet cylinder of the gas-liquid separation tank, an auxiliary cooling cylinder in a vertical direction being threadedly installed on the annular groove of the gas-liquid separation tank, a threaded cylinder on the inner circumference of the auxiliary cooling cylinder, an annular cavity in the inner wall of the auxiliary cooling cylinder, a left-right inlet external threaded cylinder on the bottom left side of the outer circumference of the auxiliary cooling cylinder, and a left-right outlet external threaded cylinder on the top right side of the outer circumference of the auxiliary cooling cylinder.
[0009] Furthermore, the detachable cover has six gripping rods arranged in a ring array around its top end face, and a discharge cylinder that runs vertically through the top of the top wall of the detachable cover. The outer circumference of the top of the discharge cylinder of the detachable cover is provided with an annular plate with mounting holes.
[0010] Furthermore, the top of the assembly ring groove of the gas-liquid separator is fitted with a removable sealing cover by threads, and the outer circumference of the removable sealing cover is threaded.
[0011] Furthermore, a sealing ring plate is provided on the outer circumference of the top of the air outlet of the spiral channel cylinder, the outer circumference of the sealing ring plate of the spiral channel cylinder is threaded, a regular hexagonal groove is provided at the center of the top end face of the spiral channel cylinder, and sealing rings are provided on the outer periphery of the upper and lower end faces of the sealing ring plate of the spiral channel cylinder.
[0012] Furthermore, a spiral plate is provided on the outer circumference of the air outlet of the spiral channel cylinder, and a vertical plate is provided on the top of the spiral plate of the spiral channel cylinder.
[0013] Furthermore, the gas-liquid separator has a spiral channel cylinder installed inside the assembly ring groove in the vertical direction via threads, and an air outlet cylinder in the vertical direction is set at the center of the spiral channel cylinder.
[0014] Compared with the prior art, the present invention has the following beneficial effects:
[0015] The auxiliary cooling cylinder is conveniently installed on the outside of the gas-liquid separator via threads, allowing the coolant to easily carry away the heat from the gas-liquid separator through the inside of the auxiliary cooling cylinder. This solves the problem that the gas-liquid separation and condensation effect of the device gradually decreases as the temperature rises, making it inconvenient to add auxiliary measures to the device to keep it at the required temperature.
[0016] The removable sealing cover is installed on the gas-liquid separator via threads for sealing. The removable sealing cover can be easily removed via threads, allowing the interior of the gas-liquid separator to be cleaned and the spiral channel cylinder to be replaced. This solves the problem that the device is welded and sealed, making it impossible to clean and replace internal components, and that it is inconvenient to add sealing measures to the device so that it can be disassembled for cleaning and replacement of components. Attached Figure Description
[0017] Figure 1 This is a schematic diagram of the main structure of this utility model.
[0018] Figure 2 This is a bottom view of the structure of this utility model.
[0019] Figure 3 This is a cross-sectional structural diagram of the present invention.
[0020] Figure 4 This is a disassembled structural diagram of the present invention.
[0021] Figure 5 This is a left view of the spiral channel cylinder of this utility model.
[0022] Figure 6 This is a left view of the gas-liquid separator of this utility model.
[0023] In the diagram: 1. Device body; 2. Gas-liquid separator; 3. Auxiliary cooling cylinder; 4. Spiral channel cylinder; 5. Removable sealing cover. Detailed Implementation
[0024] The embodiments of the present invention will be described in further detail below with reference to the accompanying drawings and examples.
[0025] Example 1:
[0026] As attached Figure 1 To be continued Figure 6 As shown:
[0027] This utility model provides a gas-liquid separation and purification device for sterile drug production, including a device body 1; the device body 1 is provided with a gas-liquid separation tank 2 in a vertical direction for easy support of various components; the bottom wall of the gas-liquid separation tank 2 has a vertically penetrating internal threaded cylinder at its center for easy valve installation via threads; the lower outer circumference of the gas-liquid separation tank 2 has a threaded annular groove for easy auxiliary cooling cylinder 3 installation via threads; the upper inner circumference of the gas-liquid separation tank 2 has a threaded assembly annular groove for easy spiral channel cylinder 4 and removable sealing cover 5 installation via threads; the upper outer side of the left side wall of the gas-liquid separation tank 2 has a horizontally penetrating inlet cylinder for easy gas and liquid entry into the gas-liquid separation tank 2. The outer circumference of the left end of the inlet cylinder is provided with an annular plate with mounting holes, which facilitates the installation of the external inlet pipe by bolt connection. The annular groove of the gas-liquid separator 2 is threaded with an auxiliary cooling cylinder 3 in the up-down direction, which facilitates the coolant to enter the auxiliary cooling cylinder 3 and remove the heat of the gas-liquid separator 2. The inner circumference of the auxiliary cooling cylinder 3 is threaded, which facilitates the installation of the gas-liquid separator 2 by thread. The inner wall of the auxiliary cooling cylinder 3 is provided with an annular cavity, which facilitates the coolant to be inside. The bottom left side of the outer circumference of the auxiliary cooling cylinder 3 is provided with a left-right inlet external threaded cylinder, which facilitates the connection of the external inlet pipe. The top right side of the outer circumference of the auxiliary cooling cylinder 3 is provided with a left-right outlet external threaded cylinder, which facilitates the connection of the external outlet pipe.
[0028] The gas-liquid separator 2 has a spiral channel cylinder 4 installed inside its assembly annular groove via threads, facilitating downward spiral flow of gas and liquid. A vertically oriented outlet cylinder is located at the center of the spiral channel cylinder 4, allowing for the discharge of gas after separation. A spiral plate is provided on the outer circumference of the outlet cylinder 4, facilitating assembly with the gas-liquid separator 2 to form a downward spiral channel. A vertical plate is provided at the top of the spiral plate of the spiral channel cylinder 4, creating a barrier to ensure downward spiral flow of gas and liquid. A closing annular plate is provided on the top outer circumference of the outlet cylinder 4 to prevent upward flow of gas and liquid. The closing annular plate of the spiral channel cylinder 4 has threads on its outer circumference, facilitating threaded installation of the spiral channel cylinder 4. A regular hexagonal groove is provided at the center of the top end face of the spiral channel cylinder 4, facilitating the passage of gas through the spiral channel cylinder 4. The spiral channel cylinder 4 is rotated and disassembled using tools. Sealing rings are provided on the outer periphery of both the upper and lower end faces of the sealing ring plate, facilitating deformation under stress to form a seal. A removable sealing cover 5 is threaded onto the top of the assembly ring groove of the gas-liquid separator 2, facilitating the sealing of the upper end of the gas-liquid separator 2. The removable sealing cover 5 has threads on its outer circumference, allowing for easy disassembly and assembly. Six vertical gripping rods are arranged in a ring array around the top end face of the removable sealing cover 5, facilitating hand gripping and rotation to engage with the threads of the removable sealing cover 5 and the gas-liquid separator 2. A vertically penetrating discharge cylinder is provided on the top wall of the removable sealing cover 5, facilitating the discharge of gas after gas-liquid separation. An annular plate with mounting holes is provided on the outer circumference of the top of the discharge cylinder of the removable sealing cover 5, facilitating the installation of external discharge pipes via bolt connections.
[0029] The specific usage and function of this embodiment are as follows:
[0030] In this utility model, when... Figure 1As shown, when assembling the main body 1, the gas-liquid separator 2 is removed and fixed. The auxiliary cooling cylinder 3 is screwed into the lower annular groove of the gas-liquid separator 2. The inlet cylinder is connected to the inlet pipe of the coolant circulation system, and the outlet cylinder is connected to the outlet pipe, thus forming a closed-loop cooling circuit. The spiral channel cylinder 4 is vertically installed into the assembly annular groove of the gas-liquid separator 2 through threads. Its spiral plate forms a spiral descending channel with the inner wall of the tank. Note that before screwing in the spiral channel cylinder 4, a sealing ring is first placed into the assembly annular groove of the gas-liquid separator 2, so that the bottom of the closed annular plate of the spiral channel cylinder 4 forms a seal with the gas-liquid separator 2. Then, a sealing ring is placed on the top of the closed annular plate of the spiral channel cylinder 4. The removable sealing cover 5 is screwed into the assembly annular groove of the gas-liquid separator 2, ensuring that the sealing ring is deformed under pressure. The system is sealed, thereby creating a seal between the top of the closed ring plate of the spiral channel cylinder 4 and the removable sealing cover 5. Then, the inlet cylinder of the gas-liquid separator 2 is connected to the external inlet pipe by bolts, and the outlet cylinder of the removable sealing cover 5 is connected to the external outlet pipe by bolts. At this point, the main body 1 of the device is assembled. When the gas-liquid mixture enters from the inlet cylinder of the gas-liquid separator 2, the gas-liquid mixture flows downward along the spiral descending channel formed by the spiral plate and the inner wall of the tank. Centrifugal motion is generated in the spiral flow channel, and the liquid is thrown towards the tank wall due to centrifugal force and gathers downward along the spiral channel. At the same time, the tank wall of the gas-liquid separator 2 is cooled by the auxiliary cooling cylinder 3, causing the gas-liquid mixture to form condensate, thereby enhancing the gas-liquid separation effect. Then, the gas that has undergone gas-liquid separation can be discharged upward through the outlet cylinder in the center of the spiral channel cylinder 4.
[0031] Example 2:
[0032] The difference from Embodiment 1 is that the regular hexagonal groove of the spiral channel cylinder 4 can also be set as a regular heptagonal groove, which makes the spiral channel cylinder 4 require a special tool that cooperates with the regular heptagonal groove to rotate, thus preventing non-workers from rotating and disassembling the spiral channel cylinder 4.
[0033] Example 3:
[0034] The difference from Embodiment 1 is that the outer circumferential surface of the grip bar of the removable cover 5 can also be set as a frosted surface, thereby increasing the friction between the outer circumferential surface of the grip bar of the removable cover 5 and the hand, and preventing the grip bar of the removable cover 5 from slipping.
Claims
1. A gas-liquid separation purifier for aseptic pharmaceutical production, characterized by: The device body (1) is provided with a gas-liquid separation tank (2) in the up-down direction, the bottom center of the bottom wall of the gas-liquid separation tank (2) is provided with an internally threaded cylinder penetrating in the up-down direction, the lower outer periphery of the gas-liquid separation tank (2) is provided with a threaded annular groove, the upper end inner periphery of the gas-liquid separation tank (2) is provided with a threaded assembly ring groove, the left side wall of the gas-liquid separation tank (2) is provided with an entering cylinder penetrating in the left-right direction on the outer side of the upper end, the left end outer periphery of the entering cylinder of the gas-liquid separation tank (2) is provided with a ring plate with mounting holes, the annular groove of the gas-liquid separation tank (2) is provided with an auxiliary cooling cylinder (3) penetrating in the up-down direction through threaded installation, the inner periphery of the auxiliary cooling cylinder (3) is provided with threads, the wall of the auxiliary cooling cylinder (3) is provided with an annular cavity, the outer periphery of the bottom left side of the auxiliary cooling cylinder (3) is provided with an inlet liquid external threaded cylinder penetrating in the left-right direction, and the outer periphery of the top right side of the auxiliary cooling cylinder (3) is provided with an outlet liquid external threaded cylinder penetrating in the left-right direction.
2. The gas-liquid separation purifier for aseptic pharmaceutical production according to claim 1, wherein: The assembly ring groove of the gas-liquid separation tank (2) is provided with a spiral channel cylinder (4) penetrating in the up-down direction through threaded installation, and the center of the spiral channel cylinder (4) is provided with an air outlet cylinder penetrating in the up-down direction.
3. The gas-liquid separation purifier for aseptic pharmaceutical production according to claim 2, wherein: The outer periphery of the top of the air outlet cylinder of the spiral channel cylinder (4) is provided with a spiral plate, and the upper end top of the spiral plate of the spiral channel cylinder (4) is provided with a vertical plate.
4. The gas-liquid separation purifier for aseptic pharmaceutical production according to claim 3, wherein: The top outer periphery of the air outlet cylinder of the spiral channel cylinder (4) is provided with a closed ring plate, the outer periphery of the closed ring plate of the spiral channel cylinder (4) is provided with threads, a regular hexagonal groove is formed in the center of the top end face of the spiral channel cylinder (4), and the outer periphery of the upper and lower end faces of the closed ring plate of the spiral channel cylinder (4) is provided with a sealing ring.
5. The gas-liquid separation purifier for aseptic pharmaceutical production as set forth in claim 2, characterized by: The top of the detachable closure cover (5) is provided with six up-down direction gripping rods arranged in a ring shape on the outer periphery of the top end face, and the top wall of the detachable closure cover (5) is provided with an exhaust cylinder penetrating in the up-down direction.
6. The gas-liquid separation purifier for aseptic pharmaceutical production according to claim 5, wherein: The top outer periphery of the exhaust cylinder of the detachable closure cover (5) is provided with a ring plate with mounting holes.