Reaction device for silica gel chromatographic column filler synthesis

Abstract

The utility model relates to a reaction device for silica gel chromatographic column filler synthesis, which belongs to the technical field of reaction devices for synthesis and comprises a tank body, the lower surface of the tank body is communicated with a discharging structure, the upper surface of the tank body is provided with a rotating mechanism, and the right side of the tank body is provided with a filtering assembly. The rotating mechanism comprises a motor fixed to the upper surface of the tank body through a mounting frame, a first transmission wheel is fixed to the outer side of an output shaft of the motor, the top wall of an inner cavity of the tank body is rotationally connected with a rotating pipe through a sealing bearing, and the top end of the rotating pipe rotationally penetrates through the tank body and extends to the upper side. The reaction device for silica gel chromatographic column filler synthesis ensures uniform heating of a silicic acid solution and improves the production quality of silica gel particles through the dual effects of hot air and the stirring pipe, uniform heating and stirring of the solution can be further promoted through distribution of air holes, impurities on the inner wall of the tank body can be effectively cleaned through a scraping frame, and the production efficiency is improved. The influence of impurities on the production of silica gel particles is prevented, and the production efficiency is improved.

Description

Technical Field

[0001] This utility model relates to the technical field of reaction apparatus for synthesis, specifically a reaction apparatus for synthesizing silica gel chromatography column packing. Background Technology

[0002] A chromatographic column is an instrument used for the separation of compounds. Different packing materials are selected based on the different compounds to be separated in order to achieve good results. Among them, silica gel packing material is the most widely used in chromatography technology because it is superior to other packing materials in terms of efficiency, hardness and performance. The current method of producing silica gel packing material is generally to produce semi-finished silica gel particles in a tank with stable temperature and pressure, and then produce silica gel packing material that can be used in chromatographic columns through subsequent processes such as aging, acid soaking, water washing and drying.

[0003] For example, CN222446449U discloses a reaction apparatus for synthesizing hydrophobic silica chromatographic column packing, including a reaction chamber. The reaction chamber contains a cleaning component and a reaction assembly. The cleaning component includes a DC motor fixedly installed on the left side of the reaction chamber, a U-shaped frame fixedly installed on the top inner side of the reaction chamber, and a rotating shaft with one end penetrating and extending into the U-shaped frame fixedly installed on the output shaft of the DC motor. This reaction apparatus for synthesizing hydrophobic silica chromatographic column packing can automatically clean the interior of the reaction chamber by setting the cleaning component, solving the problem that cleaning existing silica chromatographic column packing after synthesis is troublesome, time-consuming, and labor-intensive, resulting in low cleaning convenience. The reaction assembly also allows for more complete production of silica particles.

[0004] While the aforementioned patent solves the problem that cleaning existing silica gel chromatography column packing is troublesome and time-consuming, resulting in low cleaning convenience, the existing technology of this patent also has the problem that when the silica solution falls onto the bottom wall of the reaction chamber, the accumulated silica solution is prone to uneven heating, which will affect the production quality and efficiency of silica gel particles and reduce its practicality. Utility Model Content

[0005] To address the shortcomings of existing technologies, this invention provides a reaction apparatus for synthesizing silica gel chromatographic column packing, which has advantages such as improving the production quality and efficiency of silica gel particles. It solves the problem in existing technologies where, when the silica solution falls to the bottom wall of the reaction chamber, the accumulated silica solution is prone to uneven heating, which in turn affects the production quality and efficiency of silica gel particles and reduces practicality.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A reaction apparatus for synthesizing silica gel chromatography column packing includes a tank body, the lower surface of which is connected to a discharge structure, the upper surface of which is provided with a rotating mechanism, and the right side of which is provided with a filter assembly.

[0008] The rotating mechanism includes a motor fixed to the upper surface of the tank body by a mounting bracket. A first transmission wheel is fixed to the outer side of the motor output shaft. A rotating tube is rotatably connected to the top wall of the inner cavity of the tank body through a sealed bearing. The top end of the rotating tube rotates through the tank body and extends to the upper side. A second transmission wheel is fixed to the outer side of the top end of the rotating tube. The outer sides of the first transmission wheel and the outer sides of the second transmission wheel are connected by a belt drive. Several stirring tubes are connected to both the left and right sides of the rotating tube. Several air outlets are opened on the outer sides of the stirring tubes on both the left and right sides.

[0009] The rotating mechanism also includes a fan fixed to the right side of the tank via a mounting plate. The air outlet of the fan is fixed to a heating box via a pipe. The upper surface of the heating box is connected to a connecting pipe. An electromagnetic valve is connected to the outer side of the left side of the connecting pipe. An input pipe is connected inside the electromagnetic valve. The bottom end of the input pipe is rotatably connected to the top end of the rotating pipe via a sealed bearing.

[0010] Furthermore, several heating wires are fixed inside the heating box.

[0011] Furthermore, the rotating mechanism also includes a conveying wheel fixed to the bottom end of the rotating tube. Two connecting rods are fixed on both the left and right sides of the rotating tube. A scraper is fixed on the opposite side of the connecting rods on both the left and right sides. The opposite side of the scrapers on both the left and right sides is in contact with the left and right side walls of the inner cavity of the tank.

[0012] Furthermore, the filter assembly includes a filter frame fixed to the right side of the tank, and a removable filter screen is fixed inside the filter frame.

[0013] Furthermore, the filter assembly also includes an air inlet pipe fixed to the air inlet end of the fan, the bottom end of the air inlet pipe being connected to the upper surface of the filter frame, and a visual glass plate being fixed to the front of the filter frame.

[0014] Furthermore, a water inlet pipe is fixed to the upper surface of the tank, and the bottom end of the water inlet pipe penetrates the tank and extends into the interior.

[0015] Furthermore, a feed pipe is fixed to the upper surface of the tank, the bottom end of the feed pipe penetrates the tank and extends into the interior, and the bottom end of the feed pipe is connected to a nozzle.

[0016] Furthermore, the discharge structure includes a first discharge pipe, a manual valve is connected to the outer side of the bottom end of the first discharge pipe, and a second discharge pipe is connected to the inside of the manual valve.

[0017] Compared with the prior art, this utility model provides a reaction apparatus for synthesizing silica gel chromatography column packing material, which has the following beneficial effects:

[0018] 1. The reaction device for synthesizing silica gel chromatographic column packing ensures uniform heating of the silica solution through the dual action of hot air and stirring tube, thereby improving the production quality of silica gel particles. The distribution of air holes can further promote uniform heating and stirring of the solution, and the scraper can effectively clean impurities on the inner wall of the tank, preventing impurities from affecting the production of silica gel particles and improving production efficiency.

[0019] 2. The reaction device for synthesizing silica gel chromatographic column packing removes dust and impurities from the air through a filter screen, which can reduce the contamination of silica solution by impurities, thereby improving the purity and quality of silica gel particles. The filtered air reduces the accumulation of impurities in the pipeline, reduces the risk of pipeline blockage, and improves the operating efficiency and service life of the equipment. Clean air can ensure the normal operation of equipment such as fans and heating boxes, and reduce equipment failures caused by the accumulation of impurities. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the rotating mechanism of this utility model;

[0021] Figure 2 This is a schematic diagram of the rotating mechanism of this utility model;

[0022] Figure 3 This is a schematic diagram of the connection structure between the motor and the first transmission wheel of this utility model;

[0023] Figure 4 This is a schematic diagram of the filter assembly of this utility model.

[0024] In the diagram: 1. Tank body, 2. Discharge structure, 3. Rotating mechanism, 301. Motor, 302. First transmission wheel, 303. Rotating pipe, 304. Second transmission wheel, 305. Stirring pipe, 306. Air outlet, 307. Fan, 308. Heating box, 309. Connecting pipe, 310. Solenoid valve, 311. Input pipe, 312. Conveying wheel, 313. Connecting rod, 314. Scraper, 4. Filter assembly, 401. Filter frame, 402. Filter screen, 403. Air inlet pipe, 404. Visual glass plate, 5. Water inlet pipe, 6. Feed pipe, 7. Nozzle. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] Please see Figure 1 The reaction apparatus for synthesizing silica gel chromatography column packing material in this embodiment includes a tank 1, a discharge structure 2 connected to the lower surface of the tank 1, a rotating mechanism 3 provided on the upper surface of the tank 1, and a filter assembly 4 provided on the right side of the tank 1.

[0027] In this embodiment, a water inlet pipe 5 is fixed on the upper surface of the tank body 1. The bottom end of the water inlet pipe 5 passes through the tank body 1 and extends into the interior. A feed pipe 6 is fixed on the upper surface of the tank body 1. The bottom end of the feed pipe 6 passes through the tank body 1 and extends into the interior. A nozzle 7 is connected to the bottom end of the feed pipe 6. The discharge structure 2 includes a first discharge pipe. A manual valve is connected to the outer side of the bottom end of the first discharge pipe. A second discharge pipe is connected to the inside of the manual valve.

[0028] It should be noted that a certain amount of water can be injected into the inside of the tank 1 through the water inlet pipe 5 for cleaning.

[0029] Please see Figures 2 to 3 In this embodiment, the rotating mechanism 3 includes a motor 301 fixed to the upper surface of the tank 1 by a mounting bracket. A first transmission wheel 302 is fixed to the outer side of the output shaft of the motor 301. A rotating tube 303 is rotatably connected to the top wall of the inner cavity of the tank 1 through a sealed bearing. The top end of the rotating tube 303 rotates through the tank 1 and extends to the upper side. A second transmission wheel 304 is fixed to the outer side of the top end of the rotating tube 303. The outer side of the first transmission wheel 302 and the outer side of the second transmission wheel 304 are connected by a belt drive. Several stirring tubes 305 are connected to both the left and right sides of the rotating tube 303. Several air outlets 306 are opened on the outer side of the stirring tubes 305 on both the left and right sides.

[0030] Specifically, the rotating mechanism 3 also includes a fan 307 fixed to the right side of the tank 1 by a mounting plate. The air outlet of the fan 307 is fixed to a heating box 308 by a pipe. The upper surface of the heating box 308 is connected to a connecting pipe 309. The outer side of the left side of the connecting pipe 309 is connected to a solenoid valve 310. The inside of the solenoid valve 310 is connected to an input pipe 311.

[0031] Specifically, the bottom end of the input pipe 311 is rotatably connected to the top end of the rotating pipe 303 through a sealed bearing. Several heating wires are fixed inside the heating box 308. The rotating mechanism 3 also includes a conveying wheel 312 fixed to the bottom end of the rotating pipe 303. Two connecting rods 313 are fixed on both the left and right sides of the rotating pipe 303. A scraper 314 is fixed on the opposite side of the connecting rods 313 on both sides. Through the dual action of hot air and rotating pipe 303, the silica solution is heated evenly, improving the production quality of silica particles. The distribution of the air outlet 306 can further promote the uniform heating and stirring of the solution.

[0032] Specifically, the opposite sides of the scrapers 314 on both sides are in contact with the left and right side walls of the inner cavity of the tank 1. A certain amount of silica solution can be added into the tank 1 through the feed pipe 6. At the same time, the blower 307, motor 301, solenoid valve 310 and heating box 308 are turned on. The air outlet of the blower 307 is vented, and after being heated by the heating box 308, it flows into the interior of the input pipe 311. Then it is sprayed out through no less than two air outlets 306. When the motor 301 is started, it drives no less than two stirring tubes 305 on both sides to rotate, which can stir the silica solution inside the tank 1. With the help of several air outlets 306 on both sides, the silica solution inside the tank 1 can be uniformly stirred and heated, and then silica gel particles are produced.

[0033] It should be noted that the scrapers 314 on the left and right sides can clean the impurities attached to the inner wall of the tank 1. By opening the manual valve in the discharge structure 2, the produced silica gel particles can be discharged. The rotating conveyor wheel 312 can transport the silica solution on the bottom wall of the inner cavity of the tank 1 upwards, thereby improving the reaction effect.

[0034] Please see Figure 4 In this embodiment, the filter assembly 4 includes a filter frame 401 fixed on the right side of the tank 1, and a removable filter screen 402 is fixed inside the filter frame 401.

[0035] Specifically, the filter assembly 4 also includes an air inlet pipe 403 fixed to the air inlet end of the fan 307. The bottom end of the air inlet pipe 403 is connected to the upper surface of the filter frame 401. A visualization glass plate 404 is fixed to the front of the filter frame 401. A chromatographic column is an instrument used for the separation of compounds. Different packing materials are selected according to different compounds to be separated in order to achieve good results. Among them, silica gel packing is the most widely used in chromatography technology because it is superior to other packing materials in terms of efficiency, hardness and performance. The production method of silica gel packing is generally to produce semi-finished silica gel particles in a tank with stable temperature and pressure.

[0036] It should be noted that the filter screen 402 can filter dust in the air entering the tank 1, thereby improving the flow of the inlet pipe 311, the connecting pipe 309 and the pipeline.

[0037] The working principle of the above embodiments is as follows:

[0038] In use, a certain amount of silicate solution can be added into the tank 1 through the feed pipe 6. Simultaneously, the blower 307, motor 301, solenoid valve 310, and heating box 308 are turned on. Air is discharged from the outlet of the blower 307, heated by the heating box 308, and then flows into the input pipe 311. It is then sprayed out through at least two air outlets 306. When the motor 301 starts, it drives at least two stirring tubes 305 on the left and right sides to rotate, thus stirring the silicate solution inside the tank 1. Combined with the several air outlets 306 on the left and right sides, this stirs the silicate solution inside the tank 1. The internal silica solution is uniformly stirred and heated to produce silica gel particles. Impurities adhering to the inner wall of the tank 1 can be cleaned by the scrapers 314 on both sides. The produced silica gel particles can be discharged by opening the manual valve in the discharge structure 2. The rotating conveyor wheel 312 can transport the silica solution on the bottom wall of the inner cavity of the tank 1 upward to improve the reaction effect and improve the production quality of silica gel particles. The filter screen 402 can filter the dust in the air entering the tank 1 and improve the flow of the input pipe 311, connecting pipe 309 and pipeline.

[0039] It should be noted that the orientations or positional relationships indicated herein are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the purpose of facilitating the description of this application and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0040] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0041] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A reaction device for synthesizing a silica gel chromatographic column packing, comprising a tank body (1), characterized in that: The lower surface of the tank (1) is connected to a discharge structure (2), the upper surface of the tank (1) is provided with a rotating mechanism (3), and the right side of the tank (1) is provided with a filter assembly (4). The rotating mechanism (3) includes a motor (301) fixed to the upper surface of the tank (1) by a mounting bracket. A first transmission wheel (302) is fixed to the outer side of the output shaft of the motor (301). A rotating tube (303) is rotatably connected to the top wall of the inner cavity of the tank (1) through a sealed bearing. The top end of the rotating tube (303) rotates through the tank (1) and extends to the upper side. A second transmission wheel (304) is fixed to the outer side of the top end of the rotating tube (303). The outer side of the first transmission wheel (302) and the outer side of the second transmission wheel (304) are connected by a belt drive. Several stirring tubes (305) are connected to both the left and right sides of the rotating tube (303). Several air outlets (306) are opened on the outer side of the stirring tubes (305) on both the left and right sides. The rotating mechanism (3) also includes a fan (307) fixed to the right side of the tank (1) by a mounting plate. The air outlet of the fan (307) is fixed with a heating box (308) through a pipe. The upper surface of the heating box (308) is connected to a connecting pipe (309). The outer side of the left side of the connecting pipe (309) is connected to a solenoid valve (310). The inside of the solenoid valve (310) is connected to an input pipe (311). The bottom end of the input pipe (311) is rotatably connected to the top end of the rotating pipe (303) through a sealed bearing.

2. The reaction device for synthesizing silica gel column filler according to claim 1, characterized in that: The heating box (308) has several heating wires fixed inside.

3. The reaction device for synthesizing silica gel column filler according to claim 1, characterized in that: The rotating mechanism (3) also includes a conveying wheel (312) fixed at the bottom of the rotating tube (303). Two connecting rods (313) are fixed on both the left and right sides of the rotating tube (303). A scraper (314) is fixed on the opposite side of the connecting rods (313) on both the left and right sides. The opposite side of the scrapers (314) on both the left and right sides is in contact with the left and right side walls of the inner cavity of the tank (1).

4. The reaction device for synthesizing silica gel column filler according to claim 1, characterized in that: The filter assembly (4) includes a filter frame (401) fixed to the right side of the tank (1), and a removable filter screen (402) is fixed inside the filter frame (401).

5. The reaction device for synthesizing silica gel column filler according to claim 4, characterized in that: The filter assembly (4) also includes an air inlet pipe (403) fixed to the air inlet end of the fan (307). The bottom end of the air inlet pipe (403) is connected to the upper surface of the filter frame (401). A visual glass plate (404) is fixed to the front of the filter frame (401).

6. The reaction device for synthesizing silica gel column filler according to claim 1, characterized in that: A water inlet pipe (5) is fixed on the upper surface of the tank (1), and the bottom end of the water inlet pipe (5) penetrates the tank (1) and extends into the interior.

7. The reaction device for synthesizing silica gel column filler according to claim 1, characterized in that: The upper surface of the tank (1) is fixed with a feed pipe (6), the bottom end of the feed pipe (6) penetrates the tank (1) and extends into the interior, and the bottom end of the feed pipe (6) is connected to a nozzle (7).

8. The reaction device for synthesizing silica gel column filler according to claim 1, characterized in that: The discharge structure (2) includes a first discharge pipe, a manual valve is connected to the outside of the bottom end of the first discharge pipe, and a second discharge pipe is connected to the inside of the manual valve.

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