Self-adaptive module of micro-fluidic chip
By designing a microfluidic chip self-adaptation module, automatic adaptation and leakage detection between the microfluidic chip and the adapter are realized, solving the problems of cumbersome operation and insufficient leakage detection in the existing technology, and ensuring the safety and accuracy of the experiment.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- SOMESTECH CO LTD
- Filing Date
- 2025-04-22
- Publication Date
- 2026-04-21
AI Technical Summary
Existing microfluidic chip adapters require manual clamping, which is cumbersome and makes it impossible to detect system leaks during sample injection.
Design a microfluidic chip self-adaptation module, including a chip stage, a displacement module, an adapter, and a leakage detection module. The displacement module is used to realize the automatic adaptation between the microfluidic chip and the adapter, and the leakage detection module is used to detect leakage in real time.
It enables automatic adaptation between microfluidic chips and adapters, timely detection of system leaks, and ensures the safety and accuracy of experiments.
Smart Images
Figure CN224142298U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of microfluidics technology, and in particular to a microfluidic chip self-adaptation module. Background Technology
[0002] Currently, chip adapters used in the medical, biopharmaceutical, and chemical synthesis fields mainly consist of an adapter, an adapter top cover with inlet and outlet ports, an adapter bottom cover, an adapter clamping block, and a rotating pin. The main workflow involves placing the microfluidic chip on the adapter, then placing the adapter with the microfluidic chip on the bottom cover. The top and bottom covers open and close via the rotating pin. After the microfluidic chip is in place, the top cover is flipped to bring its sealing portion into contact with the microfluidic chip. Finally, the adapter clamping block secures the top and bottom covers, ensuring a good seal between the adapter top cover (with its connecting pipes) and the microfluidic chip's inlet and outlet ports. This allows the microfluidic chip to connect to different devices or systems.
[0003] However, due to structural limitations, the chip adapter of ordinary microfluidic chips requires manual clamping and fitting, which is cumbersome and cannot be used with experimental equipment to detect system leaks during sample injection. Utility Model Content
[0004] The main purpose of this invention is to propose a microfluidic chip self-adaptation module, which aims to achieve automatic adaptation with experimental equipment while also detecting system leakage problems.
[0005] To achieve the above objectives, this utility model proposes a microfluidic chip self-adaptation module, which includes:
[0006] A chip stage, used to fix a microfluidic chip;
[0007] A displacement module, wherein the displacement module is connected to the chip stage via a transmission mechanism;
[0008] An adapter, fixed to the displacement module and spaced apart from the chip stage, is used for communication with the sample introduction device; and
[0009] A leakage detection module is disposed on the chip stage;
[0010] The displacement module is used to drive the microfluidic chip loaded inside the chip stage to contact and conduct with the adapter; the leakage detection module is used to detect whether there is leakage of the conductive medium in the microfluidic chip when the microfluidic chip contacts and conducts with the adapter.
[0011] In one embodiment, the leakage detection module includes a leakage control circuit board and a leakage sensor disposed on the chip stage. The leakage control circuit board is electrically connected to the leakage sensor. The leakage control circuit board is used to receive the electrical signal sent by the leakage sensor and forward it to the main control circuit board of the experimental equipment, so that the main control circuit board of the experimental equipment controls the movement of the displacement module.
[0012] In one embodiment, the microfluidic chip self-adaptation module further includes:
[0013] Adapter, the adapter being disposed on the leakage control circuit board; and
[0014] An adapter circuit board is disposed on the displacement module, and the adapter circuit board is spaced apart from the chip stage;
[0015] When the adapter contacts and conducts electricity with the adapter circuit board, the leakage control circuit board is electrically connected to the main control circuit board of the experimental equipment.
[0016] In one embodiment, the chip stage includes:
[0017] A placement base is located on one side of the adapter; the placement base has a mounting slot for placing the microfluidic chip, and the leakage sensor is mounted at the bottom of the mounting slot, below the microfluidic chip; and
[0018] A movable stage is connected to one end of the placement seat adjacent to the leakage sensor, and the movable stage is drivenly connected to the displacement module; the movable stage is provided with an assembly cavity, in which the leakage control circuit board and the adapter are both installed.
[0019] In one embodiment, the microfluidic chip self-adaptation module further includes a card holder, which is mounted on the chip stage and located above the leakage sensor. The card holder is used to hold the microfluidic chip.
[0020] In one embodiment, the card holder is provided with at least two through holes;
[0021] The adapter includes:
[0022] Support frame, the support frame being mounted on the displacement module; and
[0023] A connecting arm is disposed on the support frame and spaced apart from the displacement module; the connecting arm is provided with at least one connecting pipe and at least two connecting protrusions, each of the connecting protrusions being provided with a first through hole communicating with the connecting pipe; when the connecting protrusion is used to cooperate with the through hole, the first through hole is communicating with the card box.
[0024] In one embodiment, the adapter further includes at least two elastic plugs, each elastic plug being connected to a communicating protrusion, and the elastic plug having a second through hole communicating with the first through hole.
[0025] In one embodiment, the connecting arm and the support frame enclose a mounting position; the adapter further includes a card box circuit board mounted at the mounting position;
[0026] The card box has several conductive pins on the side facing the card box circuit board. When the card box circuit board makes contact with the conductive pins, it transmits the information stored in the microfluidic chip to the main control circuit board of the experimental equipment.
[0027] In one embodiment, the displacement module includes:
[0028] The adapter is fixed to the base.
[0029] A lead screw, which is rotatably connected to the base;
[0030] A motor, wherein the motor is mounted on the base, and the output shaft of the motor is connected to one end of the lead screw; and
[0031] A slider is slidably connected to a lead screw; the chip stage is connected to the slider.
[0032] In one embodiment, the displacement module further includes two guide rails, which are spaced apart from each other on the base and located on both sides of the lead screw; the slider is slidably connected to the two guide rails.
[0033] The microfluidic chip self-adaptation module of this utility model includes a chip stage, a displacement module, an adapter, and a leakage detection module. The chip stage is used to fix the microfluidic chip; the displacement module is connected to the chip stage by transmission; the adapter is fixed to the displacement module and spaced apart from the chip stage, and the adapter is used to communicate with other devices; the leakage detection module is located on the chip stage; the displacement module is used to drive the microfluidic chip on the chip stage to contact and communicate with the adapter; the leakage detection module is used to detect whether there is leakage of the communication medium in the microfluidic chip when the microfluidic chip contacts and communicates with the adapter. The output of the displacement module is tightly connected to the chip stage, enabling precise horizontal displacement of the microfluidic chip. The displacement module drives the microfluidic chip to contact and conduct with the adapter, achieving automatic adaptation between the adapter and the microfluidic chip. After the adapter and the microfluidic chip on the chip stage are in contact and conducting, a leakage detection module detects in real time whether there is any leakage of the conductive medium in the microfluidic chip. Thus, while achieving automatic adaptation between the adapter and the microfluidic chip, it can also detect system leakage problems, allowing operators to intervene in a timely manner and ensuring the safety and accuracy of the experiment. Attached Figure Description
[0034] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without creative effort.
[0035] Figure 1 A schematic diagram of the microfluidic chip self-adaptation module provided by this utility model from one perspective;
[0036] Figure 2 Another structural schematic diagram of the microfluidic chip self-adaptation module provided by this utility model;
[0037] Figure 3 A schematic diagram of the structure of the displacement module and the chip stage of the microfluidic chip self-adaptation module provided by this utility model after assembly;
[0038] Figure 4 A schematic diagram of the structure of the chip stage of the microfluidic chip self-adaptation module provided by this utility model after removing the card box.
[0039] Explanation of icon numbers:
[0040] 10. Chip stage; 11. Placement base; 11a. Mounting slot; 12. Moving stage; 20. Displacement module; 21. Base; 22. Lead screw; 23. Motor; 24. Slider; 25. Guide rail; 30. Adapter; 31. Support frame; 32. Connecting arm; 32a. Connecting protrusion; 33. Elastic plug; 40. Leakage detection module; 41. Leakage control circuit board; 42. Leakage sensor; 50. Adapter; 60. Adapter circuit board; 70. Card box; 70a. Through hole; 80. Card box circuit board.
[0041] The realization of the purpose, functional features and advantages of this utility model will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation
[0042] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present utility model.
[0043] It should be noted that if the embodiments of this utility model involve directional indicators (such as up, down, left, right, front, back, etc.), the directional indicators are only used to explain the relative positional relationship and movement of the components in a specific posture. If the specific posture changes, the directional indicators will also change accordingly.
[0044] Furthermore, if the embodiments of this utility model involve descriptions such as "first" or "second," these descriptions are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined with "first" or "second" may explicitly or implicitly include at least one of those features. Additionally, the use of "and / or" or "and / or" throughout the text includes three parallel solutions. For example, "A and / or B" includes solution A, solution B, or a solution where both A and B are satisfied simultaneously. Furthermore, the technical solutions of the various embodiments can be combined with each other, but this must be based on the ability of those skilled in the art to implement them. When the combination of technical solutions is contradictory or impossible to implement, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection claimed by this utility model.
[0045] This invention proposes a microfluidic chip self-adaptation module.
[0046] Please see Figure 1 and Figure 2In one embodiment of this utility model, the microfluidic chip self-adaptation module includes a chip stage 10, a displacement module 20, an adapter 30, and a leakage detection module 40. The chip stage 10 is used to fix the microfluidic chip; the displacement module 20 is connected to the chip stage 10 in a transmission manner; the adapter 30 is fixed to the displacement module and spaced apart from the chip stage 10, and the adapter 30 is used to communicate with the sample injection device; the leakage detection module 40 is disposed on the chip stage 10; the displacement module 20 is used to drive the microfluidic chip loaded inside the chip stage 10 to contact and communicate with the adapter 30; the leakage detection module 40 is used to detect whether there is leakage of the conductive medium in the microfluidic chip when the microfluidic chip contacts and communicates with the adapter 30.
[0047] The microfluidic chip self-adaptive module is installed in the experimental equipment and connected to the sample injection device. The adapter 30 of the microfluidic chip self-adaptive module is connected to the sample injection device. The sample injection device is electrically connected to the main control circuit board of the experimental equipment. The leakage detection module 40 of the microfluidic chip self-adaptive module is electrically connected to the main control circuit board of the experimental equipment. The displacement module 20 of the microfluidic chip self-adaptive module is electrically connected to the main control circuit board of the experimental equipment.
[0048] The chip stage 10 is designed with appropriate dimensions and shape to ensure the microfluidic chip is securely placed on it. The output of the displacement module 20 is connected to the chip stage 10. An adapter 30 is fixed to the displacement module and spaced apart from the chip stage 10. The adapter 30 is used for communication with the sample introduction device, and its design should match the interface of the microfluidic chip to ensure smooth communication. A leakage detection module 40 is mounted on the chip stage 10. The chip stage 10 is made of high-strength material, possessing excellent stability and corrosion resistance. The leakage detection module 40 can monitor the leakage of the conductive medium in real time.
[0049] The microfluidic chip is placed on the chip stage 10 and secured with a fixing device. The displacement module 20 is activated, bringing the microfluidic chip on the chip stage 10 into contact with the adapter 30. When the microfluidic chip and adapter 30 are in contact and conducting, the leak detection module 40 begins operation, continuously monitoring for leaks in the conductive medium between the microfluidic chip and adapter 30. If the leak detection module 40 detects a leak in the microfluidic chip on the chip stage 10, it transmits a leak signal to the main control circuit board of the experimental equipment. Upon receiving the leak signal, the main control circuit board controls the injection device to stop the injection, and then resets the displacement module 20, preventing further injection of liquid into the microfluidic chip on the chip stage 10. After the abnormality is corrected, the main control circuit board of the experimental equipment re-controls the displacement module 20 to bring the microfluidic chip inside the chip stage 10 into contact with the adapter 30, continuing this process until the leak detection module 40 no longer sends a leak signal. If the leak detection module 40 does not detect a leak, the connection between the microfluidic chip and the adapter 30 remains stable, and subsequent experiments or testing operations can be carried out.
[0050] In this embodiment, the displacement module 20 is located below the chip stage 10 and is connected to the chip stage 10 via a transmission mechanism. It enables precise horizontal displacement of the microfluidic chip. The displacement module 20 drives the microfluidic chip to contact and conduct with the adapter 30, achieving automatic adaptation between the adapter 30 and the microfluidic chip. After the adapter 30 contacts and conducts with the microfluidic chip on the chip stage 10, the leakage detection module 40 detects in real time whether there is leakage of the conductive medium in the microfluidic chip. This timely detection of system leakage problems allows the main control circuit board of the experimental equipment to electrically control the displacement module 20 and the sample injection device in a timely manner, effectively intervening in the leakage problem of the microfluidic chip. It also allows the operator to adaptively adjust the position of the microfluidic chip on the chip stage 10, ensuring the safety and accuracy of the experiment.
[0051] In one embodiment, please refer to Figure 1 , Figure 2 and Figure 4 The leakage detection module 40 includes a leakage control circuit board 41 and a leakage sensor 42 disposed on the chip stage 10. The leakage control circuit board 41 is electrically connected to the leakage sensor 42. The leakage control circuit board 41 is used to receive the electrical signal sent by the leakage sensor 42 and forward it to the main control circuit board of the experimental equipment so that the main control circuit board of the experimental equipment controls the movement of the displacement module 20.
[0052] The leakage control circuit board 41, located on the chip stage 10, is the core component of the entire leakage detection module 40. The leakage control circuit board 41 includes components such as a microprocessor, memory, and input / output interfaces; it is electrically connected to the leakage sensor 42. The leakage sensor 42, also located on the chip stage 10, detects liquid leakage. The leakage sensor 42 includes a sensor body and connecting wires; the sensor body detects liquid leakage and transmits electrical signals to the leakage control circuit board 41 via the connecting wires. The leakage control circuit board 41 is electrically connected to the main control circuit board of the experimental equipment to transmit the electrical signals received by it to the main control circuit board.
[0053] The leakage control circuit board 41 and leakage sensor 42 are installed on the chip stage 10 and electrically connected. The leakage sensor 42 starts working, monitoring the liquid leakage in real time. When a liquid leakage is detected, the leakage sensor 42 sends an electrical signal to the leakage control circuit board 41. After receiving the electrical signal sent by the leakage sensor 42, the leakage control circuit board 41 forwards it to the main control circuit board of the experimental equipment. Subsequently, the main control circuit board of the experimental equipment controls the sample injection device to stop liquid injection and controls the displacement module 20 to reset. This continues until the displacement module 20 drives the microfluidic chip on the chip stage 10 to re-seal and fully seal with the adapter 30, thereby ensuring that the microfluidic chip can achieve conductive connection with other devices.
[0054] The leak control circuit board 41 features a highly integrated circuit design, providing data processing, signal transmission, and control functions. It coordinates the operation of all components to ensure the normal functioning of the leak detection module 40. The leak sensor 42 employs advanced detection technology, enabling it to detect abnormalities at the first sign of a liquid leak and quickly convert the detected information into an electrical signal. Through the collaborative work of the leak control circuit board 41 and the leak sensor 42, the leak detection module 40 achieves real-time monitoring and control of liquid leaks, effectively ensuring laboratory safety.
[0055] In one embodiment, please refer to Figures 1 to 4 The microfluidic chip self-adaptation module also includes an adapter 50 and an adapter circuit board 60. The adapter 50 is located on the leakage control circuit board 41; the adapter circuit board 60 is located on the displacement module 20, and the adapter circuit board 60 is spaced apart from the chip stage 10. When the adapter 50 and the adapter circuit board 60 are in contact and connected, the leakage control circuit board 41 is electrically connected to the main control circuit board of the experimental equipment.
[0056] The adapter 50 is mounted on the leakage control circuit board 41, and its position and structure are designed to ensure a stable connection with the leakage control circuit board 41. The adapter circuit board 60 employs a high-performance circuit design with excellent conductivity and stability.
[0057] During the connection process between the main control circuit board and the adapter circuit board 60 of the experimental equipment, the reliability of the circuit connection is ensured through carefully designed connectors or solder points. When the adapter 50 contacts and conducts with the adapter circuit board 60, the circuit connection between the leakage control circuit board 41 and the main control circuit board of the experimental equipment is achieved. This design allows the leakage control circuit board 41 to immediately sense the change when the microfluidic chip contacts and conducts with the adapter 30, and quickly instructs the displacement module 20 to stop operating through its built-in control algorithm. This instantaneous response mechanism effectively avoids excessive compression between the microfluidic chip and the adapter 30, thereby greatly reducing the risk of damage to the microfluidic chip and adapter 30 due to mechanical damage.
[0058] In one embodiment, please refer to Figures 1 to 4 The chip stage 10 includes a placement base 11 and a moving stage 12. The placement base 11 is located on one side of the adapter 30. The placement base 11 is provided with a mounting groove 11a for placing the microfluidic chip, and the leakage sensor 42 is installed at the bottom of the mounting groove 11a and located below the microfluidic chip. The moving stage 12 is connected to one end of the placement base 11 adjacent to the leakage sensor 42, and the moving stage 12 is connected to the displacement module 20. The moving stage 12 is provided with an assembly cavity, in which the leakage control circuit board 41 and the adapter 50 are both installed.
[0059] The chip stage 10 mainly consists of two parts: a placement base 11 and a moving stage 12. The placement base 11 is located on one side of the adapter 30 for easy operation and installation. The placement base 11 features a unique structural design, with a dedicated mounting slot 11a for placing the microfluidic chip. The size and shape of this mounting slot 11a match the microfluidic chip, ensuring stable placement. Furthermore, a leakage sensor 42 is located at the bottom of the mounting slot 11a to monitor for leakage under the microfluidic chip in real time, ensuring the accuracy and safety of the experiment. The placement base 11 is cleverly connected to the moving stage 12 at an angle to the sensor 42. This structure ensures the stability of the moving stage 12 and facilitates subsequent operations. The moving stage 12 is tightly connected to the output of the displacement module 20 and is located below the adapter 30, allowing full utilization of the precise control function of the displacement module 20 for accurate positioning of the microfluidic chip. The moving stage 12 has an internal assembly cavity with ample space to accommodate various components. Inside the assembly cavity, important components such as the leakage control circuit board 41 and the adapter 50 are installed. The adapter 50 is used to electrically connect with the leakage control circuit board 41, so that when the adapter 50 contacts and conducts electricity with the adapter circuit board 60, it transmits a leakage electrical signal to the main control circuit board of the experimental equipment.
[0060] The main control circuit board of the experimental equipment is responsible for controlling the entire chip stage 10, including the operation of the displacement module 20, the signal acquisition of the leakage sensor 42, and the sample injection of the adapter 30. This design allows the placement seat 11 to stably support the microfluidic chip, while the leakage control circuit board 41 and the adapter 50 are positioned on the moving stage 12, away from the microfluidic chip. This layout effectively ensures that the leakage control circuit board 41 and the adapter 50 are not easily affected by external factors such as leakage, thus ensuring the smooth progress of the experiment and the long-term stable operation of the equipment. Furthermore, this design also has advantages such as compact structure, convenient operation, and easy maintenance, providing reliable support for microfluidic chip experiments.
[0061] In one embodiment, please refer to Figures 1 to 4 The microfluidic chip self-adaptation module also includes a cartridge 70, which is installed on the chip stage 10 and located above the leakage sensor 42. The cartridge 70 is used to hold the microfluidic chip.
[0062] The cartridge 70 ensures stability and reliability during long-term use. Its internal dimensions are precisely calculated to accommodate microfluidic chips of different sizes, thus achieving self-adaptation. The cartridge 70 is located above the leak sensor 42. This design allows the leak sensor 42 to issue an alarm promptly in the event of a leak during microfluidic chip operation, ensuring the accuracy and safety of experimental data.
[0063] The cartridge 70 is a miniature component integrating multiple operational units such as sample preparation, reaction, separation, and detection. It can be customized and optimized according to different needs and application scenarios to achieve specific biochemical analysis and detection tasks. The cartridge 70 not only provides physical protection but also houses the necessary liquids, reagents, electronic components, and sensors. Its unique structural design facilitates installation and disassembly and matches the chip stage 10, ensuring its stability during use. During installation, the cartridge 70 is precisely placed on the chip stage 10, positioned directly above the leakage sensor 42. This layout allows the cartridge 70 to effectively support the microfluidic chip and monitor leakage in real time during operation.
[0064] The microfluidic chip self-adaptation module in this invention, by adding a card holder 70, not only improves the overall performance of the system but also optimizes the user experience, providing more reliable technical support for the research and application of microfluidic chips.
[0065] In one embodiment, please refer to Figures 1 to 4The card holder 70 is provided with at least two through holes 70a; the adapter 30 includes a support frame 31 and a connecting arm 32. The support frame 31 is mounted on the displacement module 20; the connecting arm 32 is provided on the support frame 31 and spaced apart from the displacement module 20; the connecting arm 32 is provided with at least one connecting pipe and at least two connecting protrusions 32a, each connecting protrusion 32a is provided with a first through hole communicating with the connecting pipe; when the connecting protrusion 32a is used to connect with the through hole 70a, the first through hole communicates with the card holder 70.
[0066] The support frame 31 of the adapter 30 is made of a robust and durable material, and its structure is designed for easy fixation to the displacement module 20. The shape and size of the support frame 31 match the displacement module 20, ensuring stable support during fixation and preventing unnecessary shaking during operation. The support frame 31 is fixed using reliable connection methods such as high-strength screws or welding, ensuring a tight connection with the displacement module 20. The connecting arm 32 is mounted on the support frame 31 and maintains a certain distance from the displacement module 20. This spacing design helps to create a certain space between the connecting arm 32 and the displacement module 20, facilitating the connection of the connecting protrusion 32a and the through hole 70a.
[0067] The connecting arm 32 is provided with at least one connecting pipe, the shape, size, and position of which correspond to the connecting protrusion 32a, so that the two can fit tightly when the connecting protrusion 32a is inserted into the connecting pipe. The connecting protrusion 32a is located on the connecting arm 32, and its shape and size match the connecting pipe. The connecting protrusion 32a is provided with a first through hole communicating with the connecting pipe. The diameter of the first through hole is slightly smaller than the diameter of the connecting pipe to ensure a tight connection when the connecting protrusion 32a is inserted into the connecting pipe. When the connecting protrusion 32a is inserted into the through hole 70a of the card holder 70, the connecting pipe communicates with the inside of the card holder 70. As the conductive medium flows through the connecting pipe, the first through hole, and the card holder 70, an electrical connection is achieved between the adapter 30 and the card holder 70.
[0068] The cartridge 70 has at least two through holes 70a, one of which is a liquid inlet and the other is a liquid outlet. One through hole communicates with the inlet hole of the sample injection device, and the other communicates with the outlet hole of the sample injection device. This design not only enhances the practicality of the cartridge 70 but also facilitates its cooperation with the adapter 30. Through the design of the through holes 70a, this invention exhibits higher efficiency in connection and communication, which is of great significance for improving the operating speed and stability of the entire system. The adapter 30 includes a support frame 31 and a connecting arm 32, wherein the support frame 31 is fixed to the displacement module 20. This design effectively improves the stability and reliability of the entire device. The fixed connection between the support frame 31 and the displacement module 20 ensures the stability and accuracy of the adapter 30 during movement, which has a positive impact on improving the accuracy and efficiency of the entire system.
[0069] In one embodiment, please refer to Figures 1 to 4 The adapter 30 also includes at least two elastic plugs 33, each elastic plug 33 being connected to a communicating protrusion 32a, and the elastic plug 33 having a second through hole communicating with the first through hole.
[0070] The elastic plug 33 is made of a material with good elasticity and wear resistance to ensure that it can effectively adapt to changes in size and shape during use. The connection between each elastic plug 33 and a connecting protrusion 32a is made of high-strength adhesive to ensure the stability and reliability of the connection.
[0071] In the design of the elastic plug 33, the second through hole on the elastic plug 33 is located at a position corresponding to the connecting protrusion 32a, so as to form a direct channel with the first through hole. The second through hole is circular in shape to correspond to the first through hole and ensure smooth passage. The diameter and depth of the second through hole are designed according to actual needs to meet the performance requirements of the adapter 30 during use.
[0072] The interconnectivity design between the second and first through holes of the elastic plug 33 allows the medium to pass smoothly through both holes during connection, reducing flow resistance. The shape and size of the elastic plug 33 are optimized so that when it is inserted into the through hole 70a, it can fully fill the space of the through hole 70a, improving the sealing effect between the cartridge 70 and the adapter 30.
[0073] In one embodiment, please refer to Figures 1 to 4 The connecting arm 32 and the support frame 31 enclose a mounting position; the adapter 30 also includes a card box circuit board 80 mounted at the mounting position; the card box 70 has several conductive pins on the side facing the card box circuit board 80, and the card box circuit board 80 is used to transmit the information stored in the microfluidic chip to the main control circuit board of the experimental equipment when it is in contact with the several conductive pins.
[0074] The connecting arm 32 and the support frame 31 cooperate to form a mounting position with specific dimensions and shape. This mounting position is specifically designed for the cartridge circuit board 80, ensuring stable installation and efficient electrical connection. A cartridge circuit board 80 is mounted at this mounting position. This cartridge circuit board 80 is an important component of the adapter 30, and its design and installation are aimed at achieving a tight fit with the connecting arm 32 and efficient conductivity.
[0075] The side of the card holder 70 facing the card holder circuit board 80 has several conductive pins. These conductive pins are distributed in a reasonable manner and correspond to the contact points of the card holder circuit board 80 to ensure a reliable electrical connection when the connecting arm 32 contacts the card holder circuit board 80.
[0076] When the conductive pin contacts the card holder circuit board 80, the main control circuit board of the experimental equipment will control whether the liquid inlet device injects liquid into the connecting arm 32 according to preset instructions. This design makes the liquid inlet process of the connecting arm 32 controllable, and can adjust the liquid inlet state according to actual needs, improving the flexibility and safety of the system.
[0077] The cartridge circuit board 80 features a unique design, with conductive pins on its side facing the cartridge circuit board 80. These conductive pins are structurally tightly connected to the cartridge circuit board 80 to ensure good contact between the cartridge circuit board 80 and the conductive pins within the space enclosed by the connecting arm 32 and the support frame 31. When the cartridge circuit board 80 is in contact with the conductive pins and conducts, it will perform its data transmission function, transmitting the information stored in the microfluidic chip to the main control circuit board of the experimental equipment.
[0078] In one embodiment, please refer to Figures 1 to 4 The displacement module 20 includes a base 21, a lead screw 22, a motor 23, and a slider 24. The adapter 30 is fixed to the base 21. The lead screw 22 is rotatably connected to the base 21. The motor 23 is located on the base 21, and the output shaft of the motor 23 is connected to one end of the lead screw 22. The slider 24 is slidably connected to the lead screw 22. The chip stage 10 is connected to the slider 24.
[0079] The adapter 30 is fixed to a preset position on the base 21, ensuring smooth connection and cooperation between the module and other devices. The lead screw 22 is a precision ball screw, possessing high transmission efficiency and precision, and is rotatably connected to a dedicated bracket on the base 21. The connection between the lead screw 22 and the base 21 is secured with high-strength bolts, ensuring the stability of the lead screw 22 during operation. The motor 23 is a high-performance servo motor, possessing excellent response speed and precise control capabilities. The motor 23 is mounted on the base 21 and tightly connected to the base 21 via a fixed bracket. The output shaft of the motor 23 is connected to one end of the lead screw 22 using a precision coupling, ensuring the precise rotation of the lead screw 22 under the drive of the motor 23. The slider 24 is a precision slider, and its sliding connection with the lead screw 22 uses a high-precision guide rail 25, allowing the slider 24 to slide smoothly and precisely on the lead screw 22. The connection between the slider 24 and the lead screw 22 is secured with high-strength bolts to ensure the stability of the slider 24 during movement.
[0080] The displacement module 20 achieves high-precision and high-stability positioning and movement control of the chip stage 10 through the precise design and coordination of components such as the base 21, lead screw 22, motor 23, slider 24 and adapter 30.
[0081] In one embodiment, please refer to Figures 1 to 4 The displacement module 20 also includes two guide rails 25, which are spaced apart on the base 21 and located on both sides of the lead screw 22; the slider 24 is slidably connected to the two guide rails 25.
[0082] The displacement module 20 mainly includes two precision guide rails 25, which are arranged at a certain interval on the base 21 and evenly distributed on both sides of the lead screw 22 to achieve balanced support on both sides of the lead screw 22. The guide rails 25 are made of high-strength, wear-resistant materials to ensure stability and reliability during long-term use.
[0083] In the displacement module 20, the two guide rails 25 are slidably connected by a high-strength, high-precision slider 24. This slider 24 possesses excellent sliding performance, enabling it to move smoothly and steadily on the guide rails 25, thus achieving the precise displacement function of the displacement module 20. The design of the slider 24 fully considers the requirements for guidance, support, and positioning, ensuring the high precision and stability of the displacement module 20 during movement.
[0084] The above description is merely an exemplary embodiment of the present utility model and does not limit the patent scope of the present utility model. Any equivalent structural transformations made based on the technical concept of the present utility model and the contents of the present utility model specification and drawings, or direct / indirect applications in other related technical fields, are included within the patent protection scope of the present utility model.
Claims
1. A microfluidic chip self-adapting module, characterized in that, The microfluidic chip self-adaptation module includes: A chip stage, used to fix a microfluidic chip; A displacement module, wherein the displacement module is connected to the chip stage via a transmission mechanism; An adapter, fixed to the displacement module and spaced apart from the chip stage, is used for communication with the sample introduction device; and A leakage detection module is disposed on the chip stage; The displacement module is used to drive the microfluidic chip loaded inside the chip stage to contact and conduct with the adapter; the leakage detection module is used to detect whether there is leakage of the conductive medium in the microfluidic chip when the microfluidic chip contacts and conducts with the adapter.
2. The microfluidic chip self-adaptation module of claim 1, wherein, The leakage detection module includes a leakage control circuit board and a leakage sensor disposed on the chip stage. The leakage control circuit board is electrically connected to the leakage sensor. The leakage control circuit board is used to receive the electrical signal sent by the leakage sensor and forward it to the main control circuit board of the experimental equipment, so that the main control circuit board of the experimental equipment controls the movement of the displacement module.
3. The microfluidic chip self-adapting module of claim 2, wherein, The microfluidic chip self-adaptation module also includes: Adapter, the adapter being disposed on the leakage control circuit board; and An adapter circuit board is disposed on the displacement module, and the adapter circuit board is spaced apart from the chip stage; When the adapter contacts and conducts electricity with the adapter circuit board, the leakage control circuit board is electrically connected to the main control circuit board of the experimental equipment.
4. The microfluidic chip self-adapting module of claim 3, wherein, The chip stage includes: A placement base is located on one side of the adapter; the placement base has a mounting slot for placing the microfluidic chip, and the leakage sensor is mounted at the bottom of the mounting slot, below the microfluidic chip; and A movable stage is connected to one end of the placement seat adjacent to the leakage sensor, and the movable stage is drivenly connected to the displacement module; the movable stage is provided with an assembly cavity, in which the leakage control circuit board and the adapter are both installed.
5. The microfluidic chip self-adaptation module of claim 2, wherein, The microfluidic chip self-adaptation module also includes a card holder, which is installed on the chip stage and located above the leakage sensor. The card holder is used to hold the microfluidic chip.
6. The microfluidic chip self-adaptation module of claim 5, wherein, The card holder is provided with at least two through holes; The adapter includes: Support frame, the support frame being mounted on the displacement module; and A connecting arm is disposed on the support frame and spaced apart from the displacement module; the connecting arm is provided with at least one connecting pipe and at least two connecting protrusions, each of the connecting protrusions being provided with a first through hole communicating with the connecting pipe; when the connecting protrusion is used to cooperate with the through hole, the first through hole is communicating with the card box.
7. The microfluidic chip self-adaptation module of claim 6, wherein, The adapter further includes at least two elastic plugs, each elastic plug being connected to a communicating protrusion, and the elastic plug having a second through hole communicating with the first through hole.
8. The microfluidic chip self-adaptation module of claim 6, wherein, The connecting arm and the support frame enclose a mounting position; the adapter also includes a card box circuit board mounted at the mounting position; The card box has several conductive pins on the side facing the card box circuit board. When the card box circuit board makes contact with the conductive pins, it transmits the information stored in the microfluidic chip to the main control circuit board of the experimental equipment.
9. The microfluidic chip self- adaptation module of claim 1, wherein, The displacement module includes: The adapter is fixed to the base. A lead screw, which is rotatably connected to the base; A motor, wherein the motor is mounted on the base, and the output shaft of the motor is connected to one end of the lead screw; and A slider is slidably connected to a lead screw; the chip stage is connected to the slider.
10. The microfluidic chip self-adaptation module of claim 9, wherein, The displacement module also includes two guide rails, which are spaced apart on the base and located on both sides of the lead screw; the slider is slidably connected to the two guide rails.