Tumor tissue detection sample storage box
By installing a temperature control device inside the storage box, and utilizing components such as a fan, heat sink, Peltier plate, and cooling pipe, the temperature inside the storage box can be regulated, solving the problem that traditional low-temperature storage boxes cannot maintain a constant temperature and ensuring the quality of tumor tissue samples.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- XINSHI BIOTECHNOLOGY (GUANGDONG) CO LTD
- Filing Date
- 2025-06-09
- Publication Date
- 2026-04-21
AI Technical Summary
Traditional low-temperature storage boxes cannot achieve constant temperature control inside the storage box, leading to temperature imbalance during long-distance transportation and affecting the quality of tumor tissue samples.
A constant temperature device is used, including a fan, heat sink, Peltier plate, return pipe and cooling pipe. Temperature sensors and controllers are used to regulate the temperature inside the storage box and maintain a constant temperature.
It achieves constant temperature control inside the storage box, ensuring that the temperature of tumor tissue samples remains stable during transportation and avoiding sample damage and sequencing data distortion.
Smart Images

Figure CN224146716U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of sample storage technology, specifically a sample storage box for tumor tissue testing. Background Technology
[0002] A tumor is a new substance formed by the proliferation of local tissue cells under the influence of various carcinogenic factors. Clinically, tumors are often divided into benign tumors and malignant tumors. After the doctor removes the tumor tissue through surgery in the operating room, it needs to be sent to the pathology department for testing. However, during the transportation of tumor tissue in an open environment, it can be contaminated by bacteria and other impurities in the external environment, causing changes in the tumor tissue and affecting the observation and testing. Therefore, a storage box is needed for transportation.
[0003] Common types of storage boxes include ambient temperature storage boxes and cryogenic storage boxes. Cryogenic storage boxes are often transported with dry ice, but they cannot be kept at a constant temperature inside. They can only be passively cooled by dry ice. However, the duration of cooling depends on the amount of dry ice and the outside temperature. During long-distance transportation, if the dry ice is exhausted, the temperature will gradually rise, causing an imbalance in the internal temperature of the storage box. This can damage the tumor tissue samples inside, leading to distortion of subsequent sequencing data. Utility Model Content
[0004] The purpose of this invention is to provide a tumor tissue testing sample storage box to solve the problem mentioned in the background art that traditional low-temperature storage boxes cannot maintain a constant temperature inside the storage box.
[0005] To achieve the above objectives, this utility model provides the following technical solution, comprising: a storage box shell, wherein a temperature control device is installed at the bottom of the inner cavity of the storage box shell, the temperature control device includes a fan, the surface of the fan is fixedly connected to the storage box shell, storage chambers are formed on both sides of the bottom of the inner cavity of the storage box shell, heat sinks are fixedly connected to both sides of the bottom of the inner cavity of the storage box shell, and Peltier plates are fixedly connected to opposite sides of the two heat sinks, the hot end of the Peltier plate is connected to the heat sink, and the cold end of the Peltier plate is connected to a return pipe, the return pipe... The surface of the reflux pipe is fixedly connected to the storage box shell. The outlet of the reflux pipe extends into the storage box shell and communicates with the storage chamber. The water supply end of the reflux pipe extends into the storage box shell and is connected to a cooling pipe. The surface of the cooling pipe is fixedly connected to the inner wall of the storage box shell. The water supply port of the cooling pipe is connected to the storage chamber through a micro water pump. A temperature sensor is fixedly connected to the top of the inner cavity of the storage box shell. The temperature sensor is electrically connected to the micro water pump and the Peltier plate through a controller. Push-out devices are installed on both the upper and lower sides of the inner cavity of the storage box shell.
[0006] Preferably, the ejection device includes two rotating rods. The top and bottom of the rotating rods are movably connected to the inner wall of the storage box housing. Gears are fixedly connected to the bottom of the rotating rod surface. Gear plates mesh on opposite sides of the two gears. A fixing plate is movably connected to the inner cavity of the gear plate. The rear side of the fixing plate is fixedly connected to the storage box housing. A placement plate is fixedly connected to the top of the gear plate, and a detection box is placed on the placement plate.
[0007] Preferably, the inner cavity of the fixing plate has limit grooves on both sides, the inner cavity of the limit groove is movably connected to the limit plate, and the two sides of the limit plate are fixedly connected to the toothed plate.
[0008] Preferably, a handle is fixedly connected to the top of the storage box shell, and the handle is wrapped with an anti-slip layer.
[0009] Preferably, a fixing strip is fixedly connected to both sides of the temperature sensor, and the rear side of the fixing strip is fixedly connected to the inner wall of the storage box housing.
[0010] Preferably, L-shaped plates are fixedly connected to both the front and rear sides of the Peltier plate, and the side of the L-shaped plate closest to the heat sink is fixedly connected to the heat sink.
[0011] Preferably, the discharge port of the reflux pipe is equipped with a sealing ring, and the opposite sides of the two sealing rings are fixedly connected to the storage chamber.
[0012] Compared with the prior art, the beneficial effects of this utility model are:
[0013] This solution allows a temperature sensor to monitor the internal temperature of the storage chamber when storing tumor tissue samples. If the temperature is too high, the temperature sensor transmits the temperature data to the controller, which activates the Peltier cooling mode. Simultaneously, a water pump is turned on to drive the coolant inside the storage chamber through the cooling pipe to cool the inside of the storage box. The liquid in the cooling pipe returns to the storage chamber through the return pipe, and the heat on the return pipe is dissipated through the heat dissipation mechanism, keeping the internal temperature at the target temperature and achieving constant temperature control. Attached Figure Description
[0014] Figure 1 This is a schematic diagram of the structure of this utility model;
[0015] Figure 2 This is a cross-sectional view of the structure of this utility model;
[0016] Figure 3 This is a cross-sectional view of the structure of this utility model;
[0017] Figure 4 This is a magnified view of a portion of the structure at point A of this utility model.
[0018] In the diagram: 1. Storage box shell; 2. Temperature control device; 201. Fan; 202. Heat sink; 203. Peltier plate; 204. Return pipe; 205. Cooling pipe; 206. Temperature sensor; 207. Fixing strip; 208. L-shaped plate; 209. Sealing ring; 3. Push-out device; 301. Rotating rod; 302. Gear; 303. Gear plate; 304. Fixing plate; 305. Placement plate; 306. Limiting groove; 307. Limiting groove; 4. Handle. Detailed Implementation
[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0020] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.
[0021] Example 1:
[0022] Please see Figure 1-4This utility model provides a technical solution: a tumor tissue detection sample storage box, comprising: a storage box shell 1, a temperature control device 2 installed at the bottom of the inner cavity of the storage box shell 1, the temperature control device 2 including a fan 201, the surface of the fan 201 being fixedly connected to the storage box shell 1, storage chambers being formed on both sides of the bottom of the inner cavity of the storage box shell 1, heat sinks 202 being fixedly connected to both sides of the bottom of the inner cavity of the storage box shell 1, and Peltier plates 203 being fixedly connected to opposite sides of the two heat sinks 202, the hot end of the Peltier plate 203 being connected to the heat sink 202, and the cold end of the Peltier plate 203 being connected to a reflux pipe 204. The surface of the return pipe 204 is fixedly connected to the storage box housing 1. The discharge port of the return pipe 204 extends into the storage box housing 1 and communicates with the storage chamber. The water supply end of the return pipe 204 extends into the storage box housing 1 and is connected to a cooling pipe 205. The surface of the cooling pipe 205 is fixedly connected to the inner wall of the storage box housing 1. The water supply port of the cooling pipe 205 is connected to the storage chamber through a micro water pump. A temperature sensor 206 is fixedly connected to the top of the inner cavity of the storage box housing 1. The temperature sensor 206 is electrically connected to the micro water pump and the Peltier plate 203 through a controller. Push-out devices 3 are installed on both the upper and lower sides of the inner cavity of the storage box housing 1.
[0023] Analysis of the above: When the storage box stores tumor tissue test samples at low temperatures, the temperature sensor 206 detects the internal temperature. If the temperature is too high, the temperature sensor 206 activates the cooling mode of the micro water pump and Peltier plate 203 via the controller. (The temperature sensor 206 adjusts the cooling power of the Peltier plate 203 based on the internal temperature difference.) The micro water pump drives the coolant inside the storage chamber into the cooling pipe 205, where it cools the interior. The coolant then enters the return pipe 204 and returns to the storage chamber. The cold end of the Peltier plate 203 is connected to the return pipe 204, which absorbs heat from the storage box shell 1 through its pipe structure. The heat is absorbed by the Peltier plate 203 through the cold end and then transferred to the heat sink 202 through the hot end. The heat is then dissipated from the heat sink into the storage box housing by the fan 201 through the heat dissipation holes. (Note: The surface of the heat dissipation chamber can be covered with a heat insulation layer on one side to prevent the temperature inside from affecting the inside of the storage box.) At the same time, the temperature data inside the storage box housing 1 is displayed on the controller's screen for easy viewing by the testing personnel. If the temperature is too low, the controller reduces the power of the micro water pump and turns on the heating function of the Peltier plate 203. Similarly, the temperature sensor 206 adjusts the heating power of the Peltier plate 203 according to the internal temperature difference. If the temperature is normal, the controller maintains the current state, thus completing the temperature control.
[0024] Example 2:
[0025] Please see Figure 1-4 This utility model provides a technical solution based on Embodiment 1: The ejection device 3 includes two rotating rods 301. The top and bottom of the rotating rods 301 are movably connected to the inner wall of the storage box housing 1. A gear 302 is fixedly connected to the bottom of the surface of the rotating rod 301. A toothed plate 303 meshes with the two gears 302 on opposite sides. A fixing plate 304 is movably connected to the inner cavity of the toothed plate 303. The rear side of the fixing plate 304 is fixedly connected to the storage box housing 1. A placement plate 305 is fixedly connected to the top of the toothed plate 303. A detection box is placed on the placement plate 305.
[0026] Analysis of the above content: When using the device, the testing personnel first open the door of the storage box shell 1, then grasp the handles on the rotating rods 301 with both hands and move them backward. At the same time, the two rotating rods 301 rotate, driving their respective gears 302 to rotate in opposite directions. During the rotation of the two gears 302, the gear plate 303 moves, which in turn moves the placement plate 305. When the test box on the placement plate 305 is fully exposed, the testing personnel can take the corresponding test sample for testing. This allows the testing personnel to easily take and place the test sample inside the back of the storage box without having to put their hands inside the box, reducing the chance of touching other test tubes or the inner wall and reducing contact contamination.
[0027] Example 3:
[0028] Please see Figure 1-4 Based on Embodiment 1, this utility model provides a technical solution: the inner cavity of the fixing plate 304 is provided with limiting grooves 306 on both sides, the inner cavity of the limiting grooves 306 is movably connected to the limiting plate 307, and the two sides of the limiting plate 307 are fixedly connected to the toothed plate 303.
[0029] Analysis of the above content: By setting the limiting groove 306 and the limiting plate 307 in cooperation, the toothed plate 303 will not detach from the storage box housing 1 when it drives the placement plate 305 to move, thus limiting its movement.
[0030] Example 4:
[0031] Please see Figure 1-4 Based on Embodiment 1, this utility model provides a technical solution: a handle 4 is fixedly connected to the top of the storage box shell 1, and the grip of the handle 4 is wrapped with an anti-slip layer.
[0032] Analysis of the above content: By combining the handle 4 with the anti-slip layer, it is easier for the testing personnel to transport the storage box. At the same time, the anti-slip layer at the handle increases the friction of the hand to prevent it from falling off.
[0033] Example 5:
[0034] Please see Figure 1-4 Based on Embodiment 1, this utility model provides a technical solution: both sides of the temperature sensor 206 are fixedly connected with fixing strips 207, and the rear side of the fixing strips 207 is fixedly connected to the inner wall of the storage box shell 1.
[0035] Analysis of the above content: The temperature sensor 206 is fixed by setting the fixing strip 207 to prevent it from being damaged if it falls due to gravity.
[0036] Example 6:
[0037] Please see Figure 1-4 Based on Embodiment 1, this utility model provides a technical solution: L-shaped plates 208 are fixedly connected to both the front and rear sides of the Peltier plate 203, and the side of the L-shaped plate 208 closest to the heat sink 202 is fixedly connected to the heat sink 202.
[0038] Analysis of the above content: By setting the L-shaped plate 208, the Peltier plate 203 and the heat sink 202 are more firmly fixed, preventing them from separating.
[0039] Example 7:
[0040] Please see Figure 1-4 Based on Embodiment 1, this utility model provides a technical solution: the discharge port of the return pipe 204 is equipped with a sealing ring 209, and the opposite sides of the two sealing rings 209 are fixedly connected to the storage chamber.
[0041] Analysis of the above content: By setting a sealing ring 209 to seal the connection between the discharge port of the return pipe 204 and the storage chamber, leakage caused by cracks at the connection during long-term use is prevented.
[0042] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. It will be apparent to those skilled in the art that this utility model is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or basic characteristics of this utility model. Therefore, the embodiments should be considered exemplary and non-limiting in all respects. The scope of this utility model is defined by the appended claims rather than the foregoing description. Therefore, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within this utility model, and no reference numerals in the claims should be construed as limiting the scope of the claims.
[0043] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.
Claims
1. A tumor tissue test sample storage cassette, characterized by, include: A storage box shell (1) is provided. A temperature control device (2) is installed at the bottom of the inner cavity of the storage box shell (1). The temperature control device (2) includes a fan (201). The surface of the fan (201) is fixedly connected to the storage box shell (1). Storage chambers are provided on both sides of the bottom of the inner cavity of the storage box shell (1). Heat sinks (202) are fixedly connected to both sides of the bottom of the inner cavity of the storage box shell (1). Peltier plates (203) are fixedly connected to opposite sides of the two heat sinks (202). The hot end of the Peltier plate (203) is connected to the heat sink (202). The cold end of the Peltier plate (203) is connected to a return pipe (204). The surface of the return pipe (204) is connected to the storage box. The housing (1) is fixedly connected, the outlet of the return pipe (204) extends into the storage box housing (1) and communicates with the storage chamber, the water supply end of the return pipe (204) extends into the storage box housing (1) and is connected to the cooling pipe (205), the surface of the cooling pipe (205) is fixedly connected to the inner wall of the storage box housing (1), the water supply port of the cooling pipe (205) is connected to the storage chamber through a micro water pump, a temperature sensor (206) is fixedly connected to the top of the inner cavity of the storage box housing (1), the temperature sensor (206) is electrically connected to the micro water pump and the Peltier plate (203) through a controller, and a push-out device (3) is installed on both the upper and lower sides of the inner cavity of the storage box housing (1).
2. The tumor tissue test sample storage box according to claim 1, characterized in that: The ejection device (3) includes two rotating rods (301). The top and bottom of the rotating rods (301) are movably connected to the inner wall of the storage box housing (1). A gear (302) is fixedly connected to the bottom of the surface of the rotating rod (301). A toothed plate (303) meshes with the two gears (302) on opposite sides. A fixing plate (304) is movably connected to the inner cavity of the toothed plate (303). The rear side of the fixing plate (304) is fixedly connected to the storage box housing (1). A placement plate (305) is fixedly connected to the top of the toothed plate (303). A detection box is placed on the placement plate (305).
3. The tumor tissue test sample storage box according to claim 2, characterized in that: The inner cavity of the fixed plate (304) has a limiting groove (306) on both sides. The inner cavity of the limiting groove (306) is movably connected to a limiting plate (307). The two sides of the limiting plate (307) are fixedly connected to the toothed plate (303).
4. The tumor tissue test sample storage box according to claim 2, characterized in that: A handle (4) is fixedly connected to the top of the storage box housing (1), and the handle (4) is wrapped with an anti-slip layer.
5. The tumor tissue sample storage box according to claim 1, characterized in that: The temperature sensor (206) is fixedly connected to both sides by fixing strips (207), and the rear side of the fixing strips (207) is fixedly connected to the inner wall of the storage box housing (1).
6. The tumor tissue test sample storage box according to claim 1, characterized in that: The Peltier plate (203) is fixedly connected to both the front and rear sides with L-shaped plates (208), and the side of the L-shaped plate (208) closest to the heat sink (202) is fixedly connected to the heat sink (202).
7. The tumor tissue test sample storage box according to claim 1, characterized in that: The discharge port of the return pipe (204) is equipped with a sealing ring (209), and the opposite sides of the two sealing rings (209) are fixedly connected to the storage chamber.