Filter press filtering mechanism for raw material medicine preparation

Abstract

The utility model discloses a filter press filtering mechanism for raw material medicine preparation, and relates to the technical field of chemical medicine production equipment. Comprising an upper filter-pressing cylinder, the lower part of the upper filter-pressing cylinder is tightly buckled with a lower filter-pressing cylinder, the upper part of the upper filter-pressing cylinder is communicated with a feeding pipe, the middle part of the side wall of the upper filter-pressing cylinder is communicated with a pressurizing pipe, the upper part of an inner cavity of the lower filter-pressing cylinder is provided with a filter cylinder, the bottom of the filter cylinder is provided with a filter plate, and the upper part of the filter plate is covered with filter cloth. A pressurizing pipe applies air pressure, a feeding pipe conveys liquid medicine to increase the air pressure of an upper filter pressing cylinder, the filtering efficiency of the liquid medicine can be effectively improved, a fixing ring presses and fixes filter cloth, and the situation that the filter cloth is separated from a filter plate, activated carbon flows into the filtered liquid medicine again through the filter plate, and then the filtering effect is poor can be effectively prevented. The zero-gas-consumption automatic drain valve can enable filtered liquid medicine to flow into the bottom of the lower filter-pressing cylinder, so that the loss of air pressure in the upper filter-pressing cylinder is avoided, and the filtering efficiency is further improved.

Description

Technical Field

[0001] This utility model relates to the field of chemical and pharmaceutical production equipment technology, specifically a filter press mechanism for preparing active pharmaceutical ingredients. Background Technology

[0002] The filter press consists of a liquid-holding cup and a filter funnel. Its key feature is that an air-pressurizing cap is installed at the top of the filter funnel to seal it. The air-pressurizing cap communicates with the inner cavity of the filter funnel via a one-way valve. A notch is opened at the bottom of the funnel, communicating with the liquid-holding cup. In drug processing, it is necessary to extract the active ingredients from the drug, and a filter press is a commonly used device in this process. However, in the production of fenalidomide, activated carbon is required to purify or decolorize the fenalidomide solution. Existing filter presses used for fenalidomide production have the following problems:

[0003] The filtration efficiency is low, relying solely on the pressure between the liquid and the filter press for filtration, resulting in a long filtration time and low efficiency.

[0004] The lack of a necessary filter cloth fixing structure can easily cause the filter cloth to shift during the process of the medicine washing the filter cloth, and the filtered material will be re-mixed into the filtrate, resulting in poor filtration effect.

[0005] Therefore, we have made improvements to this by proposing a pressure filter mechanism for the preparation of active pharmaceutical ingredients. Utility Model Content

[0006] To address the shortcomings of existing technologies, this invention provides a filter press mechanism for the preparation of active pharmaceutical ingredients, which solves the problems of poor filtration efficiency and effect in existing filter presses.

[0007] To achieve the above objectives, this utility model is implemented through the following technical solution: a filter press mechanism for preparing raw materials, including an upper filter cylinder, a lower filter cylinder tightly fastened to the lower part of the upper filter cylinder, and hydraulic cylinders symmetrically and longitudinally arranged on the side wall of the lower filter cylinder, with the piston rod of the hydraulic cylinder fixedly connected to the lower side wall of the upper filter cylinder.

[0008] The upper part of the upper pressure filter cylinder is connected to a feed pipe, which is equipped with a solenoid valve A. The middle part of the side wall of the upper pressure filter cylinder is connected to a pressure pipe, which is equipped with a solenoid valve B.

[0009] The upper part of the inner cavity of the pressure filter cartridge is provided with a filter cylinder, the bottom of the filter cylinder is provided with a filter plate, and the upper part of the filter plate is covered with filter cloth.

[0010] As a preferred embodiment, a fixing ring is pressed onto the upper part of the filter cloth. The fixing ring is fixedly connected to the top wall of the inner cavity of the upper filter cylinder by a plurality of evenly arranged connecting spring rods. One end of the connecting spring rod is fixedly connected to the upper surface of the fixing ring. When the upper and lower filter cylinders are fastened together, the fixing ring is tightly pressed onto the filter cloth.

[0011] As a preferred embodiment, a sealing ring is fixedly provided in the inner cavity of the filter cartridge opening, and a sealing groove is provided on the outer edge of the opening of the sealing ring. A rubber sealing ring is tightly fitted in the sealing groove, and the rubber sealing ring can be tightly fitted to the inner wall of the opening of the upper pressure filter cartridge.

[0012] As a preferred embodiment, the inner cavity of the pressure filter cartridge is provided with a baffle in the horizontal direction. The baffle is located at the lower part of the filter cartridge and is sealed and fixed to the inner wall of the pressure filter cartridge.

[0013] As a preferred embodiment, the baffle is connected to a zero-air-consumption automatic drain valve, which is located in the lower part of the inner cavity of the pressure filter cartridge.

[0014] As a preferred embodiment, the bottom of the pressure filter cartridge is connected to a discharge pipe, and the discharge pipe is equipped with a solenoid valve C.

[0015] As a preferred embodiment, the upper side wall of the upper pressure filter cartridge is connected to a pressure valve A, and the middle side wall of the lower pressure filter cartridge is connected to a pressure valve B, with the pressure valve B located at the lower part of the baffle.

[0016] This utility model has the following beneficial effects:

[0017] The non-naphthol solution purified by activated carbon is fed into the sealed inner cavity formed by the upper and lower pressure filter cartridges through the feed pipe. At the same time, air pressure is applied through the pressurization pipe and the air pressure valve A detects the air pressure. By applying air pressure through the pressurization pipe and feeding the solution through the feed pipe, the air pressure of the upper pressure filter cartridge is increased, which can effectively improve the filtration efficiency of the solution.

[0018] The fixing ring presses the filter cloth to prevent it from detaching from the filter plate, which would cause the activated carbon to flow back into the filtered medicine solution, resulting in poor filtration effect.

[0019] The zero-air-consumption automatic drain valve allows the filtered liquid to flow into the bottom of the lower pressure filter cartridge, preventing pressure loss in the upper pressure filter cartridge and thus improving filtration efficiency.

[0020] The hydraulic cylinder lifts the upper pressure filter cartridge, which is simple to operate and allows staff to replace the filter cloth in a timely manner.

[0021] Pressure valve B detects and releases the air pressure of the lower filter cartridge to prevent the filtered liquid from spraying out due to air pressure when it is discharged through the discharge pipe.

[0022] Of course, any product implementing this utility model does not necessarily need to achieve all of the advantages described above at the same time. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the structure of a filter press mechanism for preparing active pharmaceutical ingredients according to this utility model;

[0024] Figure 2 This is a cross-sectional structural schematic diagram of a filter press mechanism for preparing active pharmaceutical ingredients according to the present invention.

[0025] In the diagram, 1. Upper pressure filter cartridge; 2. Lower pressure filter cartridge; 3. Hydraulic cylinder; 4. Feed pipe; 5. Solenoid valve A; 6. Pressurization pipe; 7. Solenoid valve B; 8. Filter cartridge; 9. Filter plate; 10. Filter cloth; 11. Fixing ring; 12. Connecting spring rod; 13. Sealing ring; 14. Sealing groove; 15. Rubber sealing ring; 16. Baffle; 17. Zero air consumption automatic drain valve; 18. Discharge pipe; 19. Solenoid valve C; 20. Air pressure valve A; 21. Air pressure valve B. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0027] In the description of this utility model, it should be understood that the terms "opening", "upper", "lower", "thickness", "top", "middle", "length", "inner", "around" and other terms indicating orientation or positional relationship are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the components or elements referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0028] Please refer to the examples. Figures 1 to 2 This utility model provides a technical solution: a filter press mechanism for preparing raw materials, including an upper filter cylinder 1, a lower filter cylinder 2 tightly fastened to the lower part of the upper filter cylinder 1, and a hydraulic cylinder 3 symmetrically and longitudinally arranged on the side wall of the lower filter cylinder 2, with the piston rod of the hydraulic cylinder 3 fixedly connected to the lower side wall of the upper filter cylinder 1.

[0029] The upper part of the upper pressure filter cylinder 1 is connected to a feed pipe 4, and the feed pipe 4 is equipped with a solenoid valve A5. The middle part of the side wall of the upper pressure filter cylinder 1 is connected to a pressure pipe 6, and the pressure pipe 6 is equipped with a solenoid valve B7.

[0030] The upper part of the inner cavity of the pressure filter cylinder 2 is provided with a filter cylinder 8, the bottom of the filter cylinder 8 is provided with a filter plate 9, and the upper part of the filter plate 9 is covered with a filter cloth 10.

[0031] The upper part of the filter cloth 10 is pressed with a fixing ring 11. The fixing ring 11 is fixedly connected to the top wall of the inner cavity of the upper pressure filter cylinder 1 by a plurality of evenly arranged connecting spring rods 12. One end of the connecting spring rod 12 is fixedly connected to the upper surface of the fixing ring 11. When the upper pressure filter cylinder 1 and the lower pressure filter cylinder 2 are fastened together, the fixing ring 11 and the filter cloth 10 are tightly pressed together.

[0032] The filter cylinder 8 has a sealing ring 13 fixedly installed in the inner cavity of the opening. The outer edge of the opening of the sealing ring 13 has a sealing groove 14. The sealing groove 14 is tightly fitted with a rubber sealing ring 15. The rubber sealing ring 15 can be tightly fitted to the inner wall of the opening of the upper pressure filter cylinder 1.

[0033] The inner cavity of the pressure filter cartridge 2 is provided with a baffle 16 in the horizontal direction. The baffle 16 is located at the lower part of the filter cartridge 8 and is sealed and fixed to the inner wall of the pressure filter cartridge 2.

[0034] The baffle 16 is connected to a zero-air-consumption automatic drain valve 17, which is located in the lower part of the inner cavity of the pressure filter cartridge 2.

[0035] The bottom of the pressure filter cylinder 2 is connected to a discharge pipe 18, and the discharge pipe 18 is equipped with a solenoid valve C19.

[0036] The upper side wall of the upper pressure filter cylinder 1 is connected to a pressure valve A20, and the middle side wall of the lower pressure filter cylinder 2 is connected to a pressure valve B21. The pressure valve B21 is located at the lower part of the baffle 16.

[0037] The working principle of this utility model:

[0038] The non-naphthol solution purified by activated carbon is fed into the sealed inner cavity formed by the upper pressure filter cartridge 1 and the lower pressure filter cartridge 2 through the feed pipe 4. At the same time, the pressure pipe 6 applies air pressure, and the air pressure valve A20 detects the air pressure. By applying air pressure through the pressure pipe 6 and feeding the solution through the feed pipe 4, the air pressure of the upper pressure filter cartridge 1 is increased, which can effectively improve the filtration efficiency of the solution.

[0039] The fixing ring 11 presses and fixes the filter cloth 10, which can effectively prevent the filter cloth 10 from detaching from the filter plate 9, causing the activated carbon to flow back into the filtered medicine solution through the filter plate 9, thus resulting in poor filtration effect.

[0040] The zero-air-consumption automatic drain valve 17 can allow the filtered medicine to flow into the bottom of the lower pressure filter cartridge 2 without causing a loss of air pressure in the upper pressure filter cartridge 1, thereby improving the filtration efficiency.

[0041] The air pressure valve A20 detects the air pressure in the upper pressure filter cartridge 1. When the air pressure in the upper pressure filter cartridge 1 reaches the preset value, the solenoid valve A5 closes the feed pipe 4 and the solenoid valve B7 closes the pressurization pipe 6. The air pressure valve A20 detects the air pressure in the upper pressure filter cartridge 1. When the air pressure in the upper pressure filter cartridge 1 decreases, the solenoid valve B7 opens the pressurization pipe 6, and the pressurization pipe 6 continues to supply high-pressure gas.

[0042] Repeat the above steps multiple times until the pressure valve A20 detects that the pressure loss in the upper pressure filter cartridge 1 has exceeded ten minutes. Then, the solenoid valve A5 closes the feed pipe 4, the solenoid valve B7 closes the pressurization pipe 6, the pressure valve A20 opens, the pressure in the upper pressure filter cartridge 1 is discharged, the hydraulic cylinder 3 lifts the upper pressure filter cartridge 1, and the staff can replace the filter cloth 10 in time.

[0043] The air pressure valve B21 detects and releases the air pressure of the pressure filter cartridge 2 to prevent the filtered liquid from spraying out due to air pressure when it is discharged through the discharge pipe 18.

[0044] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0045] The preferred embodiments of this utility model disclosed above are merely illustrative of the present utility model. These preferred embodiments do not exhaustively describe all details, nor do they limit the utility model to the specific implementations described. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of this utility model, thereby enabling those skilled in the art to better understand and utilize it. This utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A filter press mechanism for preparing active pharmaceutical ingredients, characterized in that: It includes an upper pressure filter cylinder (1), a lower pressure filter cylinder (2) is tightly fastened to the lower part of the upper pressure filter cylinder (1), and a hydraulic cylinder (3) is symmetrically and longitudinally arranged on the side wall of the lower pressure filter cylinder (2). The piston rod of the hydraulic cylinder (3) is fixedly connected to the lower side wall of the upper pressure filter cylinder (1). The upper part of the pressure filter cylinder (1) is connected to a feed pipe (4), the feed pipe (4) is equipped with a solenoid valve A (5), and the middle part of the side wall of the pressure filter cylinder (1) is connected to a pressure pipe (6), the pressure pipe (6) is equipped with a solenoid valve B (7). The upper part of the inner cavity of the pressure filter cylinder (2) is provided with a filter cylinder (8), the bottom of the filter cylinder (8) is provided with a filter plate (9), and the upper part of the filter plate (9) is covered with a filter cloth (10).

2. The filter press filtration mechanism for preparing active pharmaceutical ingredients according to claim 1, characterized in that: The filter cloth (10) is pressed with a fixing ring (11) on the upper part. The fixing ring (11) is fixedly connected to the inner wall of the upper pressure filter cylinder (1) by a plurality of evenly arranged connecting spring rods (12). One end of the connecting spring rod (12) is fixedly connected to the upper surface of the fixing ring (11). When the upper pressure filter cylinder (1) and the lower pressure filter cylinder (2) are fastened together, the fixing ring (11) and the filter cloth (10) are tightly pressed together.

3. The filter press filtration mechanism for preparing active pharmaceutical ingredients according to claim 1, characterized in that: The filter cylinder (8) has a sealing ring (13) fixedly installed in the inner cavity of the opening. The outer edge of the opening of the sealing ring (13) has a sealing groove (14). The sealing groove (14) is tightly fitted with a rubber sealing ring (15). The rubber sealing ring (15) can be tightly fitted to the inner wall of the opening of the upper pressure filter cylinder (1).

4. A filter press filtration mechanism for preparing active pharmaceutical ingredients according to claim 1, characterized in that: The inner cavity of the pressure filter cartridge (2) is provided with a baffle (16) in the horizontal direction. The baffle (16) is located at the lower part of the filter cartridge (8) and is sealed and fixed to the inner wall of the pressure filter cartridge (2).

5. A filter press filtration mechanism for preparing active pharmaceutical ingredients according to claim 4, characterized in that: The baffle (16) is connected to a zero-air-consumption automatic drain valve (17), which is located in the lower part of the inner cavity of the pressure filter cartridge (2).

6. A filter press filtration mechanism for preparing active pharmaceutical ingredients according to claim 1, characterized in that: The bottom of the pressure filter cartridge (2) is connected to a discharge pipe (18), and the discharge pipe (18) is equipped with a solenoid valve C (19).

7. A filter press filtration mechanism for preparing active pharmaceutical ingredients according to claim 4, characterized in that: The upper side wall of the upper pressure filter cylinder (1) is connected to a pressure valve A (20), and the middle side wall of the lower pressure filter cylinder (2) is connected to a pressure valve B (21). The pressure valve B (21) is located at the lower part of the baffle (16).

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