Cell culture detection box for stem cell treatment

Abstract

The utility model discloses a cell culture detection box for stem cell treatment, and relates to the technical field of cell culture. The detection device comprises a detection box body, a mounting plate is arranged in the detection box body, a plurality of fixing grooves are formed in the mounting plate, a two-way screw rod is rotationally matched in the fixing grooves, a connecting rod is arranged at one end of the two-way screw rod, a handle is arranged at one end of the connecting rod, two moving blocks are in threaded fit with the two-way screw rod, and connecting plates are arranged on the moving blocks. And an elastic piece is arranged on one side of the connecting plate. According to the culture dish fixing device, the arc-shaped fixing plates located on the two moving blocks can be driven to move oppositely under the rotation of the two-way lead screw, so that the culture dishes can be fixed, and when the culture dishes with different sizes are fixed under the arrangement of the elastic pieces, the culture dishes can be fixed more conveniently. The culture dish is further fixed through the pressure of the elastic piece, so that the culture dish can be fixed more stably.

Description

Technical Field

[0001] This utility model belongs to the field of cell culture technology, specifically, it relates to a cell culture testing box for stem cell therapy. Background Technology

[0002] With the continuous development of society, the medical field has become a key focus for people, as it can help our bodies restore health and overcome various intractable diseases. Stem cell therapy is a new type of medical treatment, which requires the use of a corresponding stem cell therapy cell culture and testing kit.

[0003] Chinese patent application CN202122233978.0 discloses a cell culture testing box for stem cell therapy, comprising a testing box body, an arc-shaped groove, a sliding door, a connecting plate, and a horizontal plate. The horizontal plate is fixedly connected inside the testing box body, and limiting components are fixedly connected to both sides of the top of the horizontal plate. A fixing plate is fixedly connected to the surface of the testing box body above the horizontal plate. A temperature detector is fixedly connected to the inner wall of the testing box body. A heating pipe is provided at the bottom of the testing box body. Several nozzles are fixedly connected to one side of the water pipe. The sliding door is movably connected to the surface of the testing box body. This invention not only realizes the function of adjustable internal temperature and limiting the movement of internal objects during use, but also realizes the function of real-time monitoring of internal cells during use.

[0004] However, although the above-mentioned device uses a spring-loaded limiting plate to fix the culture dish, the spring is prone to loss of elasticity after a period of use. Moreover, when fixing culture dishes of different heights, the loss of spring elasticity will be accelerated after a period of use, which will cause instability when fixing the culture dish next time. Furthermore, it is easy to affect the subsequent experimental results of the cells in the culture dish during transportation.

[0005] In view of this, this utility model is hereby proposed. Utility Model Content

[0006] The technical problem to be solved by this utility model is to overcome the shortcomings of the existing technology and provide a cell culture detection box for stem cell therapy.

[0007] To solve the above-mentioned technical problems, the basic concept of the technical solution adopted by this utility model is as follows:

[0008] A cell culture testing chamber for stem cell therapy includes a testing chamber body, an installation plate inside the testing chamber body, multiple fixing slots within the installation plate, a bidirectional lead screw rotatably engaging within the fixing slots, a connecting rod at one end of the bidirectional lead screw, a handle at one end of the connecting rod, two moving blocks threaded onto the bidirectional lead screw, a connecting plate on each moving block, an elastic element on one side of the connecting plate, an arc-shaped fixing plate at one end of the elastic element, a door on one side of the testing chamber body, and a testing component and a heating mechanism disposed inside the testing chamber body.

[0009] Optionally, the elastic element includes a fixed cylinder fixedly connected to one side of the connecting plate, a spring is provided inside the fixed cylinder, and a sliding post is provided at one end of the spring that is slidably engaged in the fixed cylinder, wherein one end of the sliding post is connected to the arc-shaped fixed plate.

[0010] Optionally, the detection assembly includes a fixing plate disposed inside the detection chamber, the fixing plate being located above the mounting plate, and a camera being disposed on the fixing plate; an arc-shaped groove and a display screen are respectively disposed on one side of the chamber door, wherein the display screen is located above the arc-shaped groove and is electrically connected to the camera; the heating mechanism includes a heating tube disposed at the bottom of the inner wall of the detection chamber, the heating tube being disposed in a reciprocating curved surface shape.

[0011] Optionally, an exhaust fan is installed on one side of the testing chamber, with one end of the fan connected to the chamber. The exhaust fan allows for the rapid removal of residual volatile gases from the chamber and provides appropriate humidity to the cells inside.

[0012] Optionally, the testing chamber is equipped with a connecting pipe, and multiple nozzles are installed on one side of the connecting pipe. One end of the connecting pipe extends outside the testing chamber and is equipped with a connecting valve at the port.

[0013] Optionally, a temperature detector is installed on one side of the inner wall of the testing chamber.

[0014] By adopting the above technical solution, the present invention has the following beneficial effects compared with the prior art. Of course, any product implementing the present invention does not necessarily need to achieve all of the following advantages at the same time:

[0015] The arc-shaped fixing plate, driven by the rotation of the bidirectional screw, moves in opposite directions between the two moving blocks, thus securing the culture dish. The elastic element further secures culture dishes of different sizes through its own pressure, ensuring greater stability. The handle facilitates operation and allows for easy control of the arc-shaped fixing plate. The detection component allows for real-time observation and detection of cells within the culture dish, enabling the stem cell therapy cell culture detection box to monitor internal cells during use.

[0016] The specific embodiments of this utility model will be described in further detail below with reference to the accompanying drawings. Attached Figure Description

[0017] The accompanying drawings described below are merely some embodiments. Those skilled in the art can obtain other drawings based on these drawings without any creative effort. In the drawings:

[0018] Figure 1 This is a schematic diagram of the detection box structure according to an embodiment of the present invention;

[0019] Figure 2 This is a schematic diagram of the internal structure of the detection box according to an embodiment of the present invention;

[0020] Figure 3 This is a schematic cross-sectional view of the detection box according to an embodiment of the present invention;

[0021] Figure 4 This is a schematic diagram of the arc-shaped fixing plate structure according to an embodiment of the present invention;

[0022] Figure 5 This is a schematic diagram of the elastic element structure according to an embodiment of the present invention;

[0023] The attached diagram lists the components represented by each number as follows:

[0024] 1. Testing chamber; 2. Mounting plate; 3. Fixing groove; 4. Two-way lead screw; 5. Connecting rod; 6. Handle; 7. Moving block; 8. Connecting plate; 9. Arc-shaped fixing plate; 10. Chamber door; 11. Fixing cylinder; 12. Spring; 13. Sliding column; 14. Fixing plate; 15. Camera; 16. Arc-shaped groove; 17. Display screen; 18. Heating tube; 19. Exhaust fan; 20. Connecting pipe; 21. Nozzle; 22. Connecting valve; 23. Temperature detector.

[0025] It should be noted that these accompanying drawings and textual descriptions are not intended to limit the scope of the present invention in any way, but rather to illustrate the concept of the present invention to those skilled in the art by referring to specific embodiments. Detailed Implementation

[0026] The present invention will now be described in further detail with reference to the accompanying drawings.

[0027] Please see Figure 1-5 As shown, this embodiment provides a cell culture testing box for stem cell therapy, including a testing box body 1. A mounting plate 2 is provided inside the testing box body 1. Multiple fixing slots 3 are provided inside the mounting plate 2. A bidirectional lead screw 4 is rotatably engaged in the fixing slots 3. A connecting rod 5 is provided at one end of the bidirectional lead screw 4. A handle 6 is provided at one end of the connecting rod 5. Two moving blocks 7 are threadedly engaged on the bidirectional lead screw 4. A connecting plate 8 is provided on the moving blocks 7. An elastic element is provided on one side of the connecting plate 8. An arc-shaped fixing plate 9 is provided at one end of the elastic element. A box door 10 is provided on one side of the testing box body 1. A testing component and a heating mechanism are respectively provided inside the testing box body 1.

[0028] One application of this embodiment is as follows: In use, first open the door 10, place the cell culture dish to be cultured in the fixing groove 3 of the mounting plate 2, and rotate the handle 6 to drive the connecting rod 5 to rotate the bidirectional lead screw 4, causing the two moving blocks 7 to move synchronously in opposite directions along the bidirectional lead screw 4. The moving blocks 7, through the connecting plate 8, drive the elastic element and the arc-shaped fixing plate 9 to move laterally. Utilizing the adaptive pressure of the elastic element, the arc-shaped fixing plate 9 tightly adheres to the outer wall of culture dishes of different heights or sizes, achieving stable clamping, thus completing the use of this device.

[0029] The arc-shaped fixing plate 8, when rotated by the bidirectional screw 4, moves in opposite directions along the two moving blocks 7, thus fixing the culture dish. With the elastic element, culture dishes of different sizes are further secured by the pressure of the elastic element itself, making the fixation of the culture dish more stable. The handle 6 facilitates the operator's control of the arc-shaped fixing plate 8, making operation convenient. Furthermore, the detection component allows for real-time observation and detection of cells within the culture dish in the detection chamber 1, realizing the function of real-time monitoring of internal cells during use of this stem cell therapy cell culture detection chamber.

[0030] like Figure 4-5As shown, the elastic element in this embodiment includes a fixed cylinder 11 fixedly connected to one side of the connecting plate 8. A spring 12 is disposed inside the fixed cylinder 11, and a sliding post 13 is slidably fitted into the fixed cylinder 11 at one end of the spring 12. One end of the sliding post 13 is connected to the arc-shaped fixed plate 9. With the spring 12, after the arc-shaped fixed plate 9 is fixed under the action of the bidirectional screw 4, it can continue to drive the arc-shaped fixed plate 9 to move. During the movement, the sliding post 13 can compress the spring 12 and slide it inside the fixed cylinder 11, thereby improving the stability of the arc-shaped fixed plate 9 at one end of the sliding post 13 during movement. After the movement stops, the spring 12 can continue to drive the arc-shaped fixed plate 9 to continuously compress and fix the culture dish according to its own elastic force, further improving the stability of the culture dish.

[0031] like Figure 1-2 As shown, the detection component in this embodiment includes a fixing plate 14 disposed inside the detection chamber 1, which is located above the mounting plate 2, and a camera 15 is disposed on the fixing plate 14. An arc-shaped groove 16 and a display screen 17 are respectively disposed on one side of the chamber door 10, wherein the display screen 17 is located above the arc-shaped groove 16 and is electrically connected to the camera 15. With the camera 15, full-process visual monitoring of the cell culture process can be achieved, reducing the number of times the chamber is opened, avoiding external environmental interference, ensuring the stability of temperature and humidity inside the incubator, and transmitting the image to the display screen 17 in a timely manner for convenient detection by staff. The camera 15 can integrate various optical modules such as fluorescence or phase contrast to adapt to the monitoring needs of different cell culture experiments, enhancing the functional expandability of the detection chamber. The heating mechanism includes a heating tube 18 disposed at the bottom of the inner wall of the detection chamber 1, the heating tube 18 being arranged in a reciprocating curved surface shape. The heating tubes 18 of the heating mechanism are evenly arranged in a reciprocating curved shape on the bottom of the inner wall of the detection chamber 1. After the heating mechanism is started, the heating tubes 18 expand the heat radiation coverage area through the curved layout, so that the heat is evenly diffused from the bottom of the chamber upwards. With the real-time feedback of the temperature detector 23, the system automatically adjusts the heating power to maintain a constant temperature inside the chamber. The curved design also facilitates the flow of heat along the inner wall of the chamber, reducing local overheating or low temperature areas and ensuring the temperature uniformity of the stem cell culture environment. In addition, the heating source of the heating tubes 18 can be connected to an existing instant heating device, which can be selected according to the actual use. The curved design is adapted to the space at the bottom of the chamber, avoiding occupying too much culture area, and is also easy to clean and maintain.

[0032] like Figure 2 As shown, an exhaust fan 19 is provided on one side of the detection chamber 1 in this embodiment, and one end of the exhaust fan 19 is connected to the detection chamber 1. With the exhaust fan 19, the residual volatile gases in the chamber can be quickly discharged, and the cells inside the detection chamber 1 can be appropriately supplied with humidity.

[0033] like Figure 2-3 As shown, the detection chamber 1 in this embodiment is equipped with a connecting pipe 20, and a plurality of nozzles 21 are provided on one side of the connecting pipe 20. One end of the connecting pipe 20 extends outside the detection chamber 1 and is equipped with a connecting valve 22 at the port. The nozzles 21 facilitate the introduction of water into the detection chamber 1 and its spraying out. The connecting valve 22 facilitates connection with external equipment, making the equipment easier to use.

[0034] like Figure 2 As shown, a temperature detector 23 is installed on one side of the inner wall of the detection chamber 1 in this embodiment. With the temperature detector 23 installed, the temperature inside the detection chamber 1 can be detected, and the detected data can be transmitted to the display screen 17, so that the staff can observe the internal temperature of the detection chamber 1 in a timely manner and take corresponding actions.

[0035] This utility model is not limited to the above-described embodiments. Anyone should know that structural changes made under the guidance of this utility model, and any technical solutions that are the same as or similar to this utility model, fall within the protection scope of this utility model. Technical aspects, shapes, and structures not described in detail in this utility model are all publicly known technologies.

Claims

1. A cell culture and detection box for stem cell therapy, characterized in that, include: The test chamber (1) is equipped with a mounting plate (2) and multiple fixing slots (3). A two-way screw (4) is rotatably fitted in the fixing slots (3). A connecting rod (5) is provided at one end of the two-way screw (4). A handle (6) is provided at one end of the connecting rod (5). Two moving blocks (7) are threadedly fitted on the two-way screw (4). A connecting plate (8) is provided on the moving block (7). An elastic element is provided on one side of the connecting plate (8). An arc-shaped fixing plate (9) is provided at one end of the elastic element. A door (10) is provided on one side of the test chamber (1). The test chamber (1) is equipped with a test component and a heating mechanism.

2. The cell culture and detection chamber for stem cell therapy according to claim 1, characterized in that, The elastic element includes a fixed cylinder (11) fixedly connected to one side of the connecting plate (8), a spring (12) is provided inside the fixed cylinder (11), and a sliding column (13) that is slidably fitted inside the fixed cylinder (11) is provided at one end of the spring (12), wherein one end of the sliding column (13) is connected to the arc-shaped fixed plate (9).

3. The cell culture and detection chamber for stem cell therapy according to claim 1, characterized in that, The detection assembly includes a fixing plate (14) disposed inside the detection housing (1), the fixing plate (14) being located above the mounting plate (2), and a camera (15) being disposed on the fixing plate (14).

4. The cell culture and detection chamber for stem cell therapy according to claim 3, characterized in that, An arc-shaped groove (16) and a display screen (17) are respectively provided on one side of the door (10), wherein the display screen (17) is located above the arc-shaped groove (16) and is electrically connected to the camera (15).

5. The cell culture and detection chamber for stem cell therapy according to claim 1, characterized in that, The heating mechanism includes a heating tube (18) located at the bottom of the inner wall of the detection chamber (1), and the heating tube (18) is arranged in a reciprocating curved shape.

6. The cell culture and detection chamber for stem cell therapy according to claim 1, characterized in that, An exhaust fan (19) is provided on one side of the test chamber (1), and one end of the exhaust fan (19) is connected to the test chamber (1).

7. The cell culture and detection chamber for stem cell therapy according to claim 1, characterized in that, The testing chamber (1) is equipped with a connecting pipe (20), and a plurality of nozzles (21) are provided on one side of the connecting pipe (20). One end of the connecting pipe (20) extends to the outside of the testing chamber (1) and a connecting valve (22) is provided at the port.

8. The cell culture and detection chamber for stem cell therapy according to claim 1, characterized in that, A temperature detector (23) is installed on one side of the inner wall of the detection chamber (1).

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