Ultrasonic cell crusher

Abstract

The utility model discloses an ultrasonic cell disruption instrument and belongs to the technical field of cell disruption. Comprising a shell and a transducer body, the transducer body is fixedly connected to the inner top wall of the shell, an amplitude-change pole is connected to the driving end of the transducer body, and the transducer further comprises a positioning sleeve fixedly connected into the shell and used for containing a bearing cylinder; the electric push rods are symmetrically arranged and fixedly connected to the inner side wall of the shell, and the driving ends of the electric push rods are fixedly connected with limiting plates; the symmetrically-arranged electric push rods push the limiting plates to move, the two limiting plates abut against the side wall of the bearing cylinder when attached to each other, meanwhile, the rubber anti-skid pads are arranged on the inner side walls of the limiting plates, friction force between the limiting plates and the bearing cylinder is increased, the first magnets attracted to each other on the limiting plates are combined, the connecting stability between the limiting plates is improved, and the service life of the bearing cylinder is prolonged. The multiple measures ensure that the bearing cylinder is stably and reliably clamped, the bearing cylinder is prevented from toppling over in high-frequency vibration of cell breaking, and cell scattering is avoided.

Description

Technical Field

[0001] This utility model relates to the field of cell disruption technology, and in particular to an ultrasonic cell disruptor. Background Technology

[0002] An ultrasonic cell disruptor converts electrical energy into acoustic energy through a transducer. This energy is then transformed into numerous tiny bubbles in a liquid medium. These bubbles rapidly burst, generating energy similar to small bombs, which in turn disrupts cells and other substances.

[0003] In existing cell disruptors, the carrier tube is typically placed in the generator chamber, and then the amplitude rod is inserted into the carrier tube for disruption. However, in actual operation, the high-frequency vibration of the amplitude rod may cause the carrier tube itself to vibrate, which may lead to the risk of the carrier tube tipping over. A tipped carrier tube will cause cells to spill out, affecting the experimental process and results. Furthermore, the high-frequency vibration of the bat rod may splash some cells, and some of the splashed cells may spill out of the carrier tube, causing not only sample loss but also troublesome subsequent cleaning. Utility Model Content

[0004] The purpose of this invention is to solve the problems mentioned in the background art and to provide an ultrasonic cell disruptor.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] An ultrasonic cell disruptor includes a housing and a transducer body, the transducer body being fixedly connected to the inner top wall of the housing, and an amplitude transformer rod being connected to the drive end of the transducer body. The device also includes:

[0007] A positioning sleeve is fixedly connected in the outer shell and is located directly below the amplitude rod. The positioning sleeve is used to place the bearing cylinder.

[0008] Symmetrically arranged electric push rods are fixedly connected to the inner side wall of the housing, and a limiting plate is fixedly connected to the drive end of the electric push rod; when the electric push rod pushes the limiting plate to move, the two sets of limiting plates are in contact with each other, and the inner side wall of the limiting plate abuts against the side wall of the bearing cylinder.

[0009] Preferably, a support rod is fixedly connected to the limiting plate, and a baffle is fixedly connected to the support rod. When the limiting plate moves the baffle, the two sets of baffles are in contact with each other.

[0010] Preferably, a first magnet is fixedly connected to each of the two symmetrically arranged limiting plates, and the two sets of first magnets attract each other.

[0011] Furthermore, a second magnet is fixedly connected to each of the two symmetrically arranged baffles, and the two sets of second magnets attract each other.

[0012] Preferably, the positioning sleeve is a rubber sleeve, and the positioning sleeve has an installation groove, the diameter of which is less than or equal to the diameter of the bearing cylinder.

[0013] Furthermore, a rubber anti-slip pad is fixedly connected to the inner wall of the limiting plate.

[0014] Compared with the prior art, the present invention provides an ultrasonic cell disruptor, which has the following beneficial effects:

[0015] All parts not mentioned in this device are the same as or can be implemented using existing technology. This utility model uses symmetrically arranged electric push rods to move the limiting plates. When the two sets of limiting plates are in contact, they abut against the side wall of the bearing cylinder. At the same time, rubber anti-slip pads are provided on the inner side wall of the limiting plates to increase the friction between them and the bearing cylinder. Combined with the first magnets attracted to each other on the limiting plates, the connection stability between the limiting plates is improved. Multiple measures ensure stable and reliable clamping of the bearing cylinder, preventing it from tipping over during the high-frequency vibration of cell breakage and avoiding cell spillage.

[0016] Meanwhile, this application uses a limiting plate to move the baffle. When the two sets of baffles are in contact, they cover the carrier tube, effectively preventing cells from splashing out of the carrier tube when the amplitude rod vibrates, reducing sample loss and also reducing the difficulty of subsequent cleaning. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structure of an ultrasonic cell disruptor proposed in this utility model;

[0018] Figure 2 This is a schematic diagram of the internal structure of the outer shell of an ultrasonic cell disruptor proposed in this utility model;

[0019] Figure 3 The present invention proposes an explosion-proof ultrasonic cell disruptor. Figure 1 ;

[0020] Figure 4 The present invention proposes an explosion-proof ultrasonic cell disruptor. Figure 2 .

[0021] In the diagram: 1. Outer shell; 101. Positioning sleeve; 1011. Mounting groove; 102. Transducer body; 1021. Amplifier rod; 2. Cabinet door; 3. Electric push rod; 4. Limiting plate; 401. First magnet; 402. Rubber anti-slip pad; 5. Baffle; 501. Second magnet; 502. Support rod; 6. Bearing cylinder. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments.

[0023] Example 1:

[0024] Reference Figures 1-4 An ultrasonic cell disruptor includes a housing 1 and a transducer body 102, the transducer body 102 being fixedly connected to the inner top wall of the housing 1, and an amplitude transformer 1021 being connected to the drive end of the transducer body 102. The transducer body 102 also includes:

[0025] The positioning sleeve 101 is fixedly connected in the outer shell 1, and the positioning sleeve 101 is located directly below the amplitude rod 1021. The positioning sleeve 101 is used to place the bearing cylinder 6.

[0026] The symmetrically arranged electric push rods 3 are fixedly connected to the inner side wall of the outer shell 1. The drive end of the electric push rod 3 is fixedly connected to the limiting plate 4. When the electric push rod 3 pushes the limiting plate 4 to move, the two sets of limiting plates 4 are in contact with each other, and the inner side wall of the limiting plate 4 abuts against the side wall of the bearing cylinder 6.

[0027] It should be noted that a cabinet door 2 is rotatably connected to the outer shell 1, and an observation window can be provided on the cabinet door 2 in specific implementation.

[0028] A support rod 502 is fixedly connected to the limiting plate 4, and a baffle 5 is fixedly connected to the support rod 502. When the limiting plate 4 moves the baffle 5, the two sets of baffles 5 are in contact.

[0029] Reference Figures 2-4 Before the crushing process, the staff placed the cell-containing carrier cylinder 6 on the positioning sleeve 101, and then started the transducer body 102 to insert the amplitude rod 1021 into the carrier cylinder 6. At this time, the electric push rod 3 was started, which will push the limit plate 4 connected to its drive end to move. After the two sets of limit plates 4 have moved a certain distance, the two sets of limit plates 4 will stick together. At this time, the two sets of limit plates 4 will abut against the side wall of the carrier cylinder 6, and the carrier cylinder 6 can be stably clamped.

[0030] Reference Figures 2-4 The movement of the limiting plate 4 will synchronously drive the support rod 502 and the baffle 5 to move. When the two sets of limiting plates 4 are in contact, the two sets of baffles 5 will be in contact simultaneously, and the bottom wall of the baffle 5 will be in contact with the top wall of the bearing cylinder 6. When the two sets of baffles 5 are in contact, the baffle 5 will cover the bearing cylinder 6. At this time, the transducer body 102 can be started for crushing.

[0031] It should be noted that, in actual implementation, the diameter of the baffle 5 is greater than or equal to the inner diameter of the bearing cylinder 6, so as to ensure that the baffle 5 can stably block the splashing of cells.

[0032] Two sets of symmetrically arranged limiting plates 4 are each fixedly connected with a first magnet 401, and the two sets of first magnets 401 attract each other.

[0033] Reference Figure 3 , Figure 4 When the two sets of limiting plates 4 are in contact, the first magnets 401 on the two sets of limiting plates 4 will attract each other. The attraction of the two sets of first magnets 401 will improve the connection stability of the two sets of limiting plates 4, thereby ensuring the clamping effect of the two sets of limiting plates 4 on the bearing cylinder 6. This will ensure that the bearing cylinder 6 will not tip over due to high-frequency vibration when the cells are broken, effectively preventing the cells from spilling into the interior of the outer shell 1.

[0034] Two sets of symmetrically arranged baffles 5 are each fixedly connected with a second magnet 501, and the two sets of second magnets 501 attract each other.

[0035] Reference Figure 3 , Figure 4 When the two sets of baffles 5 are in contact, the second magnets 501 on the two sets of baffles 5 will attract each other. The attraction of the two sets of second magnets 501 will improve the connection stability of the two sets of baffles 5, and make the two sets of baffles 5 stably and tightly attached. This effectively solves the problem that some cells are easily shaken out of the bearing cylinder 6 when the amplitude rod 1021 vibrates the cells.

[0036] The positioning sleeve 101 is a rubber sleeve, and the positioning sleeve 101 has an installation groove 1011. The diameter of the installation groove 1011 is less than or equal to the diameter of the bearing cylinder 6.

[0037] Reference Figure 3 , Figure 4 When the staff puts the bearing cylinder 6 into the positioning sleeve 101, since the positioning sleeve 101 is a rubber sleeve, the positioning sleeve 101 can effectively wrap the bearing cylinder 6, thereby improving the installation stability of the bearing cylinder 6.

[0038] Reference Figure 3 , Figure 4 In practice, a rubber anti-slip pad 402 is fixedly connected to the inner wall of the limiting plate 4.

[0039] By using the rubber anti-slip pad 402 installed on the inner side wall of the limiting plate 4, when the two sets of limiting plates 4 clamp the bearing cylinder 6, the friction between the limiting plate 4 and the bearing cylinder 6 can be increased, thereby improving the clamping effect of the limiting plate 4 on the bearing cylinder 6.

[0040] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. An ultrasonic cell disruptor, comprising a housing (1) and a transducer body (102), wherein the transducer body (102) is fixedly connected to the inner top wall of the housing (1), and an amplitude transformer (1021) is connected to the drive end of the transducer body (102), characterized in that, Also includes: The positioning sleeve (101) is fixedly connected in the outer shell (1) and the positioning sleeve (101) is located directly below the amplitude rod (1021). The positioning sleeve (101) is used to place the bearing cylinder (6). Symmetrically arranged electric push rods (3) are fixedly connected to the inner side wall of the outer shell (1). A limiting plate (4) is fixedly connected to the drive end of the electric push rod (3). When the electric push rod (3) pushes the limiting plate (4) to move, the two sets of limiting plates (4) are in contact with each other, and the inner side wall of the limiting plate (4) abuts against the side wall of the bearing cylinder (6).

2. The ultrasonic cell disruptor according to claim 1, characterized in that, A support rod (502) is fixedly connected to the limiting plate (4), and a baffle (5) is fixedly connected to the support rod (502). When the limiting plate (4) moves the baffle (5), the two sets of baffles (5) are in contact with each other.

3. The ultrasonic cell disruptor according to claim 1, characterized in that, Two sets of symmetrically arranged limiting plates (4) are each fixedly connected with a first magnet (401), and the two sets of first magnets (401) attract each other.

4. The ultrasonic cell disruptor according to claim 2, characterized in that, Two sets of symmetrically arranged baffles (5) are each fixedly connected with a second magnet (501), and the two sets of second magnets (501) attract each other.

5. The ultrasonic cell disruptor according to claim 1, characterized in that, The positioning sleeve (101) is a rubber sleeve, and the positioning sleeve (101) has an installation groove (1011) on it. The diameter of the installation groove (1011) is less than or equal to the diameter of the bearing cylinder (6).

6. An ultrasonic cell disruptor according to claim 5, characterized in that, A rubber anti-slip pad (402) is fixedly connected to the inner wall of the limiting plate (4).

Images