Dihydroergoline mesylate discharging and sterilizing device

Abstract

The utility model relates to the technical field of dihydroergoline mesylate preparation, in particular to a dihydroergoline mesylate discharging and sterilizing device which comprises a sterilizing cylinder, a stirring assembly used for uniformly sterilizing dihydroergoline mesylate is arranged in the sterilizing cylinder, and the stirring assembly comprises an inner cylinder fixedly connected to the interior of the sterilizing cylinder. According to the utility model, through the structural design of the stirring assembly, the central cylinder in the inner cylinder and the stirring plate, dihydroergoline mesylate can be effectively and uniformly stirred, so that the uniformity of materials is ensured, and the sterilization effect is improved; meanwhile, by arranging a ventilation pipe and forming holes in the outer part of the center cylinder, when the center cylinder drives the stirring plates to stir, air is blown into the center cylinder through the ventilation pipe, so that the air is blown into the inner cylinder through the outer part of the center cylinder, and an auxiliary stirring effect is achieved; the problem that the materials are adhered to the outside of the central cylinder and cannot be fully sterilized is avoided.

Description

Technical Field

[0001] This utility model relates to the field of preparation technology of dihydroergot methanesulfonate, and in particular to a sterilization device for discharging dihydroergot methanesulfonate. Background Technology

[0002] Dihydroergotamine mesylate is a widely used drug for treating migraines. Its preparation involves several precise steps, including dissolving, mixing, filtering, and discharging. The final discharging process is crucial to ensuring the drug's sterility. If effective sterilization is not carried out during production, bacteria, mold, or other microbial contamination may occur in the product, which could affect the drug's efficacy or patient safety.

[0003] In existing technologies, the current sterilization device for dihydroergot sulfonate discharge involves piling all the material in a sterilization chamber for sterilization, and then discharging the material through the bottom outlet after sterilization. Because dihydroergot sulfonate is in powder form, it is difficult for the material to be sterilized evenly when piled together, resulting in incomplete sterilization and the need for secondary sterilization. Furthermore, because dihydroergot sulfonate is often piled together for extended periods during sterilization, it is easily affected by high temperatures and prone to clumping, leading to inconsistent quality in the discharged material. Utility Model Content

[0004] In view of this, the purpose of this utility model is to propose a sterilization device for dihydroergot methanesulfonate discharge, so as to solve the problems of poor sterilization effect and poor quality of the discharged material after sterilization in existing sterilization devices.

[0005] To achieve the above objectives, this utility model provides a sterilization device for discharging dihydroergot sulfonate, comprising a sterilization cylinder. Inside the sterilization cylinder is an agitation assembly for uniformly sterilizing dihydroergot sulfonate. The agitation assembly includes an inner cylinder fixedly connected to the inside of the sterilization cylinder, and a central cylinder rotatably connected inside the inner cylinder. A ventilation pipe is connected to the bottom of the central cylinder. A distribution assembly is located at the bottom of the inner cylinder, used to filter the sterilized dihydroergot sulfonate, thereby promoting the output of dihydroergot sulfonate of different specifications from different channels.

[0006] Preferably, a feed pipe is fixedly connected to the top of the sterilization cylinder, the output end of the feed pipe is connected to the top of the inner cylinder, and a motor is fixedly connected to the top of the sterilization cylinder, the output end of the motor passing through the top of the inner cylinder and fixedly connected to the top of the central cylinder.

[0007] Preferably, an agitator is fixedly connected to the outside of the central cylinder. The agitator is spiral in shape, and its outer wall is in contact with the inner wall of the inner cylinder.

[0008] Preferably, a coil is fixedly connected to the outside of the inner cylinder, the coil is located between the sterilization cylinder and the inner cylinder, the input end of the coil passes through the side wall of the sterilization cylinder and is connected to a water inlet pipe, and the output end of the coil passes through the side wall of the sterilization cylinder and is connected to a water outlet pipe.

[0009] Preferably, the sidewall of the central cylinder is provided with a plurality of holes at equal intervals in an annular shape, a connecting ring is fixedly connected to the bottom of the inner cylinder, the top of the connecting ring is connected to the central cylinder, and a ventilation pipe is fixedly connected to the bottom of the connecting ring, the bottom end of the ventilation pipe penetrating the bottom of the inner cylinder.

[0010] Preferably, the top of the connecting ring is provided with a sliding groove, the bottom end of the central cylinder is rotatably engaged with the inside of the sliding groove, and the top end of the ventilation pipe is connected to the bottom end of the central cylinder.

[0011] Preferably, a material passage pipe is connected to the middle of the ventilation pipe, the position of the material passage pipe is on the same straight line as the position of the central cylinder, and a plug is connected to the external thread at the bottom of the material passage pipe.

[0012] Preferably, the material distribution assembly includes a fine material pipe and a coarse material pipe connected to one side of the bottom of the inner cylinder. A first filter plate is fixedly connected inside the end of the fine material pipe that connects to the inner cylinder, and a second filter plate is fixedly connected inside the end of the coarse material pipe that connects to the inner cylinder. The size of the internal holes of the first filter plate is smaller than the size of the internal holes of the second filter plate.

[0013] Preferably, the fine material tube and the coarse material tube are respectively threaded with baffles, one side of each baffle is in contact with one side of the first filter plate and the second filter plate, and the two baffles are respectively fixedly connected with connecting rods on the side away from the first filter plate and the second filter plate, and the length of the connecting rods is longer than the length of the fine material tube and the coarse material tube.

[0014] Preferably, the tops of the fine material pipe and the coarse material pipe are connected to a drain pipe at an inclined angle, and a cover plate is installed at one end of the drain pipe.

[0015] The beneficial effects of this utility model are:

[0016] 1. The agitation components and the structural design of the inner cylinder's central cylinder and agitator effectively and uniformly stir dihydroergot methanesulfonate, ensuring material uniformity and improving sterilization efficiency. Simultaneously, the ventilation pipes and openings on the outside of the central cylinder allow air to be blown into the inner cylinder as it agitates, assisting in agitation and preventing materials from adhering to the outside of the central cylinder and failing to achieve sufficient sterilization. This also prevents excessively high temperatures inside the inner cylinder from causing material clumping. Furthermore, the spiral agitator continuously propels the material, ensuring a relatively uniform thermal environment throughout the sterilization process, which helps shorten sterilization time and improve sterilization efficiency.

[0017] The designed material distribution components, including the fine and coarse material pipes, allow for precise flow separation based on the different specifications of dihydroergot methanesulfonate. This ensures that materials of different specifications can pass smoothly through different channels, preventing mixing and guaranteeing accurate material classification, thereby improving the quality of the output. Additionally, the included unblocking pipes can be opened during the discharge process to clear any blockages in the fine and coarse material pipes, preventing material from clogging the pipes. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only for this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of the overall three-dimensional structure of the present invention;

[0020] Figure 2 This is a side view sectional view of the sterilization cylinder and inner cylinder of this utility model;

[0021] Figure 3 This is an enlarged structural diagram of the central cylinder and stirring plate of this utility model;

[0022] Figure 4 This is a side view sectional structural diagram of the central cylinder and ventilation pipe of this utility model;

[0023] Figure 5 This is a schematic diagram of the bottom cross-sectional structure of the inner cylinder of this utility model;

[0024] Figure 6 This is a side view cross-sectional structural diagram of the fine material tube of this utility model.

[0025] The diagram is marked as follows:

[0026] 1. Sterilization cylinder; 2. Inner cylinder; 3. Coil; 4. Water inlet pipe; 5. Water outlet pipe; 6. Feed pipe; 7. Motor; 8. Fine feed pipe; 9. Coarse feed pipe; 10. Unblocking pipe; 11. Cover plate; 12. Central cylinder; 13. Stirring plate; 14. Ventilation pipe; 15. Feed pipe; 16. Plug; 17. Connecting ring; 18. Slide groove; 19. First filter plate; 20. Second filter plate; 21. Baffle; 22. Connecting rod. Detailed Implementation

[0027] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to specific embodiments.

[0028] It should be noted that, unless otherwise defined, the technical or scientific terms used in this utility model should have the ordinary meaning understood by one of ordinary skill in the art to which this utility model pertains. The terms "first," "second," and similar terms used in this utility model do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Terms such as "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed following the word and their equivalents, without excluding other elements or objects. Terms such as "connected" or "linked" are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. Terms such as "upper," "lower," "left," and "right" are used only to indicate relative positional relationships; when the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0029] Such as this utility model Figures 1 to 6 The present invention provides a sterilization device for discharging dihydroergot sulfonate, including a sterilization cylinder 1. The sterilization cylinder 1 is provided with an agitation component for uniformly sterilizing dihydroergot sulfonate. The agitation component includes an inner cylinder 2 fixedly connected to the inside of the sterilization cylinder 1. A central cylinder 12 is rotatably connected to the inside of the inner cylinder 2. A ventilation pipe 14 is connected to the bottom of the central cylinder 12. A distributing component is provided at the bottom of the inner cylinder 2. The distributing component is used to filter the sterilized dihydroergot sulfonate and promote the output of dihydroergot sulfonate of different specifications from different channels.

[0030] The agitation components and the structural design of the central cylinder 12 and agitator 13 inside the inner cylinder 2 effectively and uniformly stir dihydroergot methanesulfonate, ensuring material uniformity and improving sterilization effect. Simultaneously, the ventilation pipe 14 and the holes on the outside of the central cylinder 12 allow air to be blown into the interior of the central cylinder 12 through the ventilation pipe 14 while the central cylinder 12 is agitating with the agitator 13. This helps to agitate the material, preventing it from sticking to the outside of the central cylinder 12 and hindering sterilization. It also prevents excessively high temperatures inside the inner cylinder 2 from causing material clumping. Furthermore, the spiral agitator 13 continuously pushes the material, ensuring it remains in a relatively uniform thermal environment during sterilization, which helps to shorten sterilization time and improve sterilization efficiency.

[0031] like Figures 1 to 4 As shown, a feed pipe 6 is fixedly connected to the top of the sterilization cylinder 1, and the output end of the feed pipe 6 is connected to the top of the inner cylinder 2. A motor 7 is fixedly connected to the top of the sterilization cylinder 1, and the output end of the motor 7 passes through the top of the inner cylinder 2 and is fixedly connected to the top of the central cylinder 12. An agitator 13 is fixedly connected to the outside of the central cylinder 12. The agitator 13 is spiral in shape, and the outer wall of the agitator 13 is in contact with the inner wall of the inner cylinder 2. A coil 3 is fixedly connected to the outside of the inner cylinder 2. The coil 3 is located between the sterilization cylinder 1 and the inner cylinder 2. The input end of the coil 3 passes through the side wall of the sterilization cylinder 1 and is connected to a water inlet pipe 4. The output end of the coil 3 passes through the side wall of the sterilization cylinder 1 and is connected to a water outlet pipe 5.

[0032] During sterilization, the materials are first fed into the inner cylinder 2 through the feed pipe 6 via the water pipe 6. Then, hot water is poured into the water pipe 4. Through heat transfer, the water pipe heats the side wall of the inner cylinder 2, thereby causing the materials inside the inner cylinder 2 to undergo high-temperature sterilization. At the same time, the motor 7 can be started to make the central cylinder 12, along with the agitator 13, stir inside the inner cylinder 2. The spiral agitator 13 can continuously push the materials, keeping them in a relatively uniform thermal environment during the sterilization process. This helps to shorten the sterilization time and improve the sterilization efficiency, while also preventing the materials from clumping together. Furthermore, the sterilization cylinder 1 and the inner cylinder 2 together make the sterilization device a double-layer structure, preventing burns to workers from the outside.

[0033] like Figures 2 to 4As shown, the side wall of the central cylinder 12 is provided with multiple holes at equal intervals in an annular shape. A connecting ring 17 is fixedly connected to the bottom of the inner cylinder 2. The top of the connecting ring 17 is connected to the central cylinder 12. A ventilation pipe 14 is fixedly connected to the bottom of the connecting ring 17. The bottom end of the ventilation pipe 14 passes through the bottom of the inner cylinder 2. A sliding groove 18 is provided on the top of the connecting ring 17. The bottom end of the central cylinder 12 is rotatably engaged with the inside of the sliding groove 18. The top end of the ventilation pipe 14 is connected to the bottom end of the central cylinder 12.

[0034] With the ventilation pipe 14 and multiple holes on the side wall of the central cylinder 12, when the central cylinder 12 rotates with the stirring plate 13, gas can be supplied from the input end of the ventilation pipe 14 into the interior of the ventilation pipe 14. The gas will then be blown out from the multiple holes on the side wall of the central cylinder 12, thereby agitating the material and assisting the stirring plate 13 in agitation. This also prevents the material from sticking to the outside of the central cylinder 12 and failing to be sterilized. Additionally, by supplying hot and cold gases from the ventilation pipe 14 into the interior of the inner cylinder 2, the internal temperature of the inner cylinder 2 can be regulated. Furthermore, with the connecting ring 17, when the central cylinder 12 rotates, the bottom of the central cylinder 12 will rotate on the top of the connecting ring 17, thus preventing the central cylinder 12 from causing the ventilation pipe 14 to rotate.

[0035] like Figure 3 As shown, the ventilation pipe 14 is connected to the middle of the material passage pipe 15. The position of the material passage pipe 15 is on the same straight line as the position of the central cylinder 12. The bottom of the material passage pipe 15 is connected to the external thread of the plug 16.

[0036] With the feed pipe 15 in place, after all the materials have been conveyed out, some materials will enter the interior of the central cylinder 12. At this time, by opening the feed pipe 15, some materials will be conveyed out from the interior of the central cylinder 12, thereby avoiding the problem of blockage inside the central cylinder 12.

[0037] like Figure 1 , Figure 5 and Figure 6 As shown, the material distribution assembly includes a fine material pipe 8 and a coarse material pipe 9 connected to one side of the bottom of the inner cylinder 2. A first filter plate 19 is fixedly connected inside the end of the fine material pipe 8 that is connected to the inner cylinder 2, and a second filter plate 20 is fixedly connected inside the end of the coarse material pipe 9 that is connected to the inner cylinder 2. The size of the holes inside the first filter plate 19 is smaller than the size of the holes inside the second filter plate 20.

[0038] The design of the feed distribution components, specifically the fine feed tube 8 and coarse feed tube 9, allows for precise diversion of materials according to their different specifications. This ensures that materials of different specifications can pass smoothly through different channels, preventing mixing and guaranteeing accurate material classification, thereby improving the quality of the output. During use, after all materials have been sterilized, rotating the two connecting rods 22, using their threads, moves them away from the interior of the fine feed tube 8 and coarse feed tube 9, opening the discharge ports of the first filter plate 19 and the second filter plate 20. At this point, the coarse material is filtered through the second filter plate 20 and output from the interior of the coarse feed tube 9, while the fine material is filtered through the first filter plate 19 and output from the interior of the fine feed tube 8. This improves the quality of the materials and prevents mixing of coarse and fine materials. Furthermore, the baffle 21, during the initial sterilization process, can be rotated to block one side of the first filter plate 19 and the second filter plate 20, preventing materials from flowing out of the fine feed tube 8 and the coarse feed tube 9.

[0039] like Figure 1 As shown, baffles 21 are threadedly connected to the inside of the fine material pipe 8 and the coarse material pipe 9 respectively. One side of the two baffles 21 is in contact with one side of the first filter plate 19 and the second filter plate 20 respectively. A connecting rod 22 is fixedly connected to the side of the two baffles 21 away from the first filter plate 19 and the second filter plate 20 respectively. The length of the connecting rod 22 is longer than the length of the fine material pipe 8 and the coarse material pipe 9. The top of the fine material pipe 8 and the coarse material pipe 9 are connected to a drain pipe 10 at an inclined angle. A cover plate 11 is installed at one end of the drain pipe 10.

[0040] During the material discharge process, the cover plate 11 can be opened using the unblocking pipe 10 to unclog the inside of the fine material pipe 8 and the coarse material pipe 9, thereby avoiding the problem of material clogging the material pipe.

[0041] Those skilled in the art should understand that the discussion of any of the above embodiments is merely exemplary and is not intended to imply that the scope of the present invention (including the claims) is limited to these examples; within the framework of the present invention, the technical features of the above embodiments or different embodiments can also be combined, the steps can be implemented in any order, and there are many other variations of the different aspects of the present invention as described above, which are not provided in the details for the sake of brevity.

[0042] This utility model is intended to cover all such substitutions, modifications, and variations that fall within the broad scope of the appended claims. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A sterilization device for discharging dihydroergot methanesulfonate, comprising a sterilization cylinder (1), characterized in that, The sterilization cylinder (1) is equipped with an agitation assembly for uniformly sterilizing dihydroergot methanesulfonate. The agitation assembly includes an inner cylinder (2) fixedly connected to the inside of the sterilization cylinder (1). A central cylinder (12) is rotatably connected inside the inner cylinder (2). A ventilation pipe (14) is connected to the bottom of the central cylinder (12). The bottom of the inner cylinder (2) is provided with a material distribution component, which is used to filter the sterilized dihydroergot methanesulfonate and promote the output of dihydroergot methanesulfonate of different specifications from different channels.

2. The sterilization device for discharging dihydroergot methanesulfonate according to claim 1, characterized in that, The top of the sterilization cylinder (1) is fixedly connected to a feed pipe (6), the output end of the feed pipe (6) is connected to the top of the inner cylinder (2), and the top of the sterilization cylinder (1) is fixedly connected to a motor (7), the output end of the motor (7) passes through the top of the inner cylinder (2) and is fixedly connected to the top of the central cylinder (12).

3. The sterilization device for discharging dihydroergot methanesulfonate according to claim 2, characterized in that, A stirring plate (13) is fixedly connected to the outside of the central cylinder (12). The stirring plate (13) is spiral in shape, and the outer wall of the stirring plate (13) is in contact with the inner wall of the inner cylinder (2).

4. The sterilization device for discharging dihydroergot alkali mesylate according to claim 1, characterized in that, The inner cylinder (2) is fixedly connected to a coil (3). The coil (3) is located between the sterilization cylinder (1) and the inner cylinder (2). The input end of the coil (3) passes through the side wall of the sterilization cylinder (1) and is connected to a water inlet pipe (4). The output end of the coil (3) passes through the side wall of the sterilization cylinder (1) and is connected to a water outlet pipe (5).

5. The sterilization device for discharging dihydroergot methanesulfonate according to claim 2, characterized in that, The side wall of the central cylinder (12) is provided with multiple holes at equal intervals in a ring. A connecting ring (17) is fixedly connected to the bottom of the inner cylinder (2). The top of the connecting ring (17) is connected to the central cylinder (12). A ventilation pipe (14) is fixedly connected to the bottom of the connecting ring (17). The bottom end of the ventilation pipe (14) penetrates the bottom of the inner cylinder (2).

6. The sterilization device for discharging dihydroergot methanesulfonate according to claim 5, characterized in that, The top of the connecting ring (17) is provided with a sliding groove (18), the bottom end of the central cylinder (12) is rotatably engaged with the inside of the sliding groove (18), and the top end of the ventilation pipe (14) is connected to the bottom end of the central cylinder (12).

7. The sterilization device for discharging dihydroergot methanesulfonate according to claim 6, characterized in that, The ventilation pipe (14) is connected to a feed pipe (15) in the middle. The feed pipe (15) is located on the same straight line as the central cylinder (12). A plug (16) is connected to the external thread at the bottom of the feed pipe (15).

8. The sterilization device for discharging dihydroergot methanesulfonate according to claim 1, characterized in that, The material distribution assembly includes a fine material pipe (8) and a coarse material pipe (9) connected to one side of the bottom of the inner cylinder (2). A first filter plate (19) is fixedly connected inside the end of the fine material pipe (8) that is connected to the inner cylinder (2). A second filter plate (20) is fixedly connected inside the end of the coarse material pipe (9) that is connected to the inner cylinder (2). The size of the holes inside the first filter plate (19) is smaller than the size of the holes inside the second filter plate (20).

9. The sterilization device for discharging dihydroergot methanesulfonate according to claim 8, characterized in that, The fine material tube (8) and the coarse material tube (9) are respectively threaded with baffles (21). One side of each baffle (21) is in contact with one side of the first filter plate (19) and the second filter plate (20). The two baffles (21) are respectively fixedly connected with connecting rods (22) on the side away from the first filter plate (19) and the second filter plate (20). The length of the connecting rods (22) is longer than the length of the fine material tube (8) and the coarse material tube (9).

10. The sterilization device for discharging dihydroergot methanesulfonate according to claim 9, characterized in that, The tops of the fine material pipe (8) and the coarse material pipe (9) are connected to a dredging pipe (10) at an inclined angle, and a cover plate (11) is installed at one end of the dredging pipe (10).

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