Clamping assembly suitable for seed cryopreservation tube

Abstract

The utility model discloses a clamping assembly suitable for a seed cryopreservation tube, which comprises a telescopic ring, a clamping unit and a fixing ring, the telescopic ring comprises a connecting piece, a female buckle and a male buckle, the connecting piece is an elastic connecting piece, and the female buckle is matched with the male buckle; during use, the female buckle and the male buckle are buckled to form an annular structure; the connecting piece is provided with an epitaxial sleeve used for placing a chip. The number of the clamping units is at least three, and a cavity I used for containing a seed cryopreservation tube is formed among the clamping units; the clamping unit comprises a clamping piece and a thorn block; the at least two thorn blocks are arranged on the outer sides of the clamping pieces in the longitudinal direction. The sizes of the thorn blocks are gradually increased from top to bottom, and cavities II used for limiting the fixing rings are formed between the adjacent thorn blocks. The inner diameter of the fixing ring is larger than the outer diameter of the seed cryopreservation tube, and the inner side of the fixing ring is matched with the outer side of the clamping unit. The clamping assembly is used for being simply, conveniently and stably clamped on the outer wall of the seed cryopreservation tube, seed information is provided through the connected chips, and the seed information is rapidly and efficiently verified / checked.

Description

Technical Field

[0001] This utility model relates to a clamping device, and more particularly to a clamping assembly suitable for seed cryopreservation tubes, belonging to the field of vaccine safety production technology. Background Technology

[0002] Vaccines are biological products prepared against various pathogenic microorganisms and used for preventive inoculation. For vaccine production, various pathogen strains are generally used to prepare master seeds and working seeds. In order to ensure the stability of the seeds, the master seeds and working seeds need to be freeze-dried in a sterile environment and sealed in seed cryovials and stored in an ultra-low temperature freezer at -80°C.

[0003] Currently, in order to comply with GMP requirements, vaccine manufacturers need to regularly inventory their seed banks and verify information such as batch numbers and expiration dates of various seeds. In addition, during the actual production process, seed bank cryopreservation tubes may be transferred between different ultra-low temperature freezers. When transferring, it is also necessary to verify information such as batch numbers and expiration dates of various seeds. The batch numbers and expiration dates of seeds are generally printed on labels and pasted on the tube walls.

[0004] When verifying / checking seed information, operators must remove the seed bank cryopreservation tubes from the ultra-low temperature freezer and verify / check them one by one at room temperature. This operation has the following problems:

[0005] 1) Labels may detach easily in ultra-low temperature environments;

[0006] 2) Seed cryopreservation tubes are generally small in diameter (6-12mm), so the paper surface of the label is extremely small, which greatly limits the font size of the printed text on the label and the amount of information the label can carry. This affects the efficiency of visually identifying the information on the label. Therefore, when manually verifying the information on the label, not only may human error be introduced, but it also takes a long time and exposes the seeds to room temperature for a long time, which will have an adverse effect on the stability of the seeds.

[0007] 3) Operators need to wear heat-resistant gloves to prevent frostbite. However, because the heat-resistant gloves are thick, operators cannot handle the seed cryopreservation tubes flexibly, which poses a risk of dropping the seed cryopreservation tubes from their hands. This will not only cause economic losses but also pollute the surrounding environment.

[0008] Although the existing technology CN212665845U discloses a "cryopreservation tube tweezers", in which the left and right tweezer tips are inserted into the top of the cryopreservation tube cap, and the left and right tweezer tips are forcefully expanded and embedded into the cryopreservation tube cap before being lifted to remove the cryopreservation tube, the cryopreservation tube is prone to falling off once the force is released; moreover, the operation is relatively complicated and does not meet the rapid requirements of large-scale inventory in seed banks.

[0009] Therefore, there is an urgent need for a device that can effectively identify seed information, is easy to use, and can avoid human error and operational mistakes. Summary of the Invention

[0010] To address the aforementioned problems in existing technologies, a clamping assembly suitable for seed cryopreservation tubes is proposed. In this technical solution, a telescopic ring, a clamping unit, and a fixing ring are arranged in a coordinated manner to easily and securely clamp the seed cryopreservation tube to its outer wall. Seed information is provided via a connected chip, enabling rapid and efficient verification / checking of seed information.

[0011] To achieve the above technical objectives, the following technical solution is proposed:

[0012] The purpose of this technical solution is to provide: a clamping assembly suitable for seed cryopreservation tubes, including a telescopic ring, a clamping unit disposed at the top of the telescopic ring, and a fixing ring for sleeved on the outside of the clamping unit, wherein,

[0013] Telescopic ring: includes a connector, a female buckle, and a male buckle. The connector is an elastic connector (to achieve telescopic movement). The female buckle and the male buckle are respectively located at both ends of the connector, and the female buckle and the male buckle cooperate with each other. In use, the female buckle and the male buckle are engaged to form a ring structure (for tightly fitting onto the outer wall of the seed cryopreservation tube). The connector is also provided with an epitaxial sleeve for inserting the chip.

[0014] Clamping units: at least three, with cavities I forming between the clamping units to accommodate the seed cryopreservation tube; each clamping unit includes a clamping plate and spikes for preventing the retaining ring from retracting; there are at least two spikes, arranged longitudinally on the outside of the clamping plate; the size of the spikes gradually increases from top to bottom, and cavities II for limiting the retaining ring are formed between adjacent spikes. Preferably, the spikes are evenly distributed on the outside of the clamping plate;

[0015] Fixing ring: The inner diameter is larger than the outer diameter of the seed cryopreservation tube, and the inner side of the fixing ring matches the clamping unit.

[0016] Preferably, the connector is a connecting strip or a connecting piece made of a flexible material (such as phenyl silicone rubber or polyurethane elastomer). The width of the connecting strip or connecting piece can be adjusted according to actual needs, and preferably the width is 5-15mm.

[0017] Preferably, the female buckle is provided with multiple slots for limiting the male buckle (thereby further expanding the adjustable range of the telescopic ring size); in use, the appropriate slot is selected according to the outer diameter of the seed cryopreservation tube, and then the buckle is fastened.

[0018] Preferably, the outer sleeve incorporates a chip for storing and retrieving seed information; more preferably, the chip is an RFID chip.

[0019] Preferably, the connector, the outer sleeve, and the clamping unit are integrally formed.

[0020] Preferably, there are 3-6 clamping units.

[0021] Preferably, the shape of the inner side of the clamping piece matches the shape of the outer side of the seed cryopreservation tube; more preferably, the inner side of the clamping piece is arc-shaped.

[0022] Preferably, the inner side of the clamping piece is provided with a plurality of elastic protrusions, and more preferably, the elastic protrusions are evenly distributed on the inner side of the clamping piece.

[0023] Preferably, the spike is a right-angled triangular spike, with the bottom surface of the spike perpendicular to the clamping plate.

[0024] Preferably, the inner side of the fixing ring is in contact with the outer side of the spike block.

[0025] Preferably, the clamping assembly is made of an elastic material resistant to -90°C (such as phenyl silicone rubber or polyurethane elastomer), that is, the telescopic ring, clamping unit and fixing ring involved are all made of phenyl silicone rubber or polyurethane elastomer.

[0026] In this technical solution, the positional relationships involved, such as "outer side", "top", "both ends", "between", "longitudinal", "from top to bottom", "inner side", and "upper", are defined according to the actual usage conditions and are conventional terms in this technical field, as well as conventional terms used by those skilled in the art in actual use.

[0027] The beneficial technical effects of adopting this technical solution are as follows:

[0028] I. In the clamping assembly provided by this utility model, the telescopic ring, clamping unit, and fixing ring are arranged in combination to ensure that the operator can easily, quickly, and securely clamp the seed cryopreservation tube to the outer wall and achieve a tight connection between the two, wherein:

[0029] 1) The size of the telescopic ring can be adjusted by using flexible connectors and / or female buckles with multiple slots; the telescopic ring can be adapted to seed cryopreservation tubes with different outer diameters and can provide an installation position for the clamping unit, thereby ensuring the practicality of this clamping assembly.

[0030] 2) The combination of the clamping unit and the fixing ring is also applicable to seed cryopreservation tubes with different outer diameters, ensuring that this clamping assembly has a wide range of applications and can meet actual needs;

[0031] 3) The design of the combination of the spikes and the fixing ring in the clamping unit allows the clamping assembly to be securely fitted onto the outer wall of the seed cryopreservation tube.

[0032] 4) In the clamping unit, the arc-shaped design of the inner side of the clamping plate can increase its fit with the outer wall of the seed cryopreservation tube; the elastic protrusion design on the inner side of the clamping plate helps to increase the friction between the clamping plate and the outer wall of the seed cryopreservation tube, so as to further prevent slippage.

[0033] Second, in this utility model, the chip (e.g., an RFID chip) used for storing seed information in the outer sleeve is tightly connected to the seed cryopreservation tube via a connector, meeting the GMP data integrity principle. System scanning replaces manual visual identification of extremely small characters, enabling rapid and reliable information verification and reducing human error. Furthermore, compared to traditional methods of labeling and manual sorting, it eliminates the need to wear heat-resistant gloves to handle and sort the seed cryopreservation tubes, thereby reducing the risk of the tubes falling and avoiding economic losses and environmental pollution. Attached Figure Description

[0034] Figure 1 This is a schematic diagram of the seed cryopreservation tube involved in this utility model;

[0035] Figure 2 This is a schematic diagram showing the state during the assembly process of this utility model;

[0036] Figure 3 This is a schematic diagram of the working state of this utility model when clamping the seed cryopreservation tube;

[0037] Figure 4 This is a schematic diagram showing the unfastened state of the female and male buckles in this utility model.

[0038] In the figure, 1. Telescopic ring, 11. Connector, 12. Male buckle, 13. Female buckle; 2. Clamping unit, 21. Clamping piece, 22. Spike, 23. Elastic protrusion; 3. Fixing ring, 4. Cavity I, 5. Outer sleeve, 6. Cavity II, 7. Seed cryopreservation tube, 8. Slot. Detailed Implementation

[0039] The technical solutions in the embodiments of this utility model will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. Based on the embodiments of this utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of this utility model.

[0040] Example 1

[0041] This embodiment provides: a clamping assembly suitable for seed cryopreservation tubes, such as... Figure 2 As shown, it includes a telescopic ring 1, a clamping unit 2 disposed on the top of the telescopic ring 1, and a fixing ring 3 for sleeved on the outside of the clamping unit 2, wherein,

[0042] Telescopic ring 1: includes a connector 11, a female buckle 13, and a male buckle 12. The connector 11 is an elastic connector 11 (to achieve telescopic movement). The female buckle 13 and male buckle 12 are respectively located at both ends of the connector 11. The female buckle 13 cooperates with the male buckle 12 (preferably, the female buckle 13 has multiple slots 8 for limiting the male buckle 12, such as...). Figure 4 (As shown); In use, the female buckle 13 and the male buckle 12 engage to form a ring structure, which is used to fit onto the outer wall of the seed cryopreservation tube 7 (as shown). Figure 1 , Figure 3 (As shown); the connector 11 is provided with an outer sleeve 5 for inserting a chip (for storing seed information). The telescopic ring 1 can be adjusted to extend or retract according to the outer diameter of the seed cryopreservation tube 7;

[0043] Clamping unit 2: at least three, with a cavity I4 formed between the clamping units 2 to accommodate the seed cryopreservation tube 7; the clamping unit 2 includes a clamping plate 21 and spikes 22 for preventing the fixing ring 3 from retracting; there are at least two spikes 22, which are arranged longitudinally on the outside of the clamping plate 21; the size of the spikes 22 gradually increases from top to bottom, and a cavity II6 for limiting the fixing ring 3 is formed between adjacent spikes 22. Preferably, the spikes 22 are evenly distributed on the outside of the clamping plate 21;

[0044] Fixing ring 3: The inner diameter is larger than the outer diameter of the seed cryopreservation tube 7, and the inner side of the fixing ring 3 is matched with the clamping unit 2.

[0045] The system, through the coordinated arrangement of telescopic ring 1, clamping unit 2, and fixing ring 3, ensures that the seed cryopreservation tube 7 can be securely, easily, and quickly clamped onto its outer wall.

[0046] In addition, the clamping plate 21 is provided with a barb 22 to prevent the fixing ring 3 from retracting, and the inner side of the fixing ring 3 is configured to cooperate with the clamping unit 2. Based on the seed cryopreservation tubes 7 with different outer diameters, the fixing ring 3 can be fitted onto the barb 22 of different sizes to ensure that the structure fits tightly with the seed cryopreservation tube 7, while not damaging the seed cryopreservation tube 7, thus meeting GMP requirements.

[0047] Example 2

[0048] Based on Embodiment 1, this embodiment makes the following further improvements to the connector 11 in the telescopic ring 1:

[0049] 1) The connector 11 is a flexible material (phenyl silicone rubber or polyurethane elastomer) connecting strip or a flexible material (such as phenyl silicone rubber or polyurethane elastomer) connecting piece. Its length can be adjusted according to the different outer diameters of the seed cryopreservation tubes 7. The telescopic ring 1 is then fastened by the male buckle 12 and female buckle 13 set at both ends of the connecting strip. The width of the connecting strip or connecting piece can be adjusted according to actual needs; for example, in order to improve the stability of clamping the seed cryopreservation tube 7, the width of the connecting strip or connecting piece is set to 5-15mm. This width better ensures the contact area between the connecting strip or connecting piece and the seed cryopreservation tube 7.

[0050] 2) An RFID chip for storing seed information is embedded in the outer sleeve 5 on the connector 11. This clamping assembly ensures that the RFID chip is tightly connected to the seed cryopreservation tube 7 and does not detach, while not damaging the seed cryopreservation tube 7. This achieves a one-to-one correspondence between the RFID chip and the seed cryopreservation tube 7, ensuring the uniqueness of the seed cryopreservation tube 7 identification and meeting GMP requirements.

[0051] Among them, the seed cryopreservation tubes 7 are marked with RFID chips, which makes it easy for operators to quickly read the name, number, batch number, preparation date, expiration date and other information of the stored seeds when conducting seed bank inventory. This greatly reduces the time required for seed bank inventory. At the same time, it also eliminates the need for traditional operations such as wearing heat-resistant gloves to handle cryopreservation tubes, manually checking seed information and sorting, thereby avoiding the risk of cryopreservation tubes falling from hands and human error.

[0052] Example 3

[0053] Based on embodiments 1-2, this embodiment makes the following improvements to ensure the structural integrity between the telescopic ring 1 and the clamping unit 2:

[0054] In one implementation, the connector 11 and the outer sleeve 5 in the telescopic ring 1 are integrally formed, the connector 11 and the female buckle 13 are integrally formed, and the connector 11 and the male buckle 12 are integrally formed; all components of the clamping unit 2 (clamping piece 21, spike 22) are integrally formed, and the connector 11, the outer sleeve 5, and the clamping unit 2 are integrally formed. This arrangement can effectively ensure the structural integrity between the telescopic ring 1 and the clamping unit 2, thereby improving the stability of clamping the seed cryopreservation tube 7, while also achieving ease of operation;

[0055] As another implementation, the connector 11 is detachably connected to the female buckle 13, and the connector 11 is detachably connected to the male buckle 12. This arrangement allows for the selection of female buckles 13 and male buckles 12 with different structures and mating relationships according to actual needs, to fit seed cryopreservation tubes with different outer diameters, and also facilitates operator operation.

[0056] Example 4

[0057] Based on embodiments 1-3, this embodiment makes the following further improvements to the clamping unit 2:

[0058] 1) Set the number of clamping units 2 to 3-6. Further limit the number of clamping units 2 to ensure the stability of clamping the seed cryopreservation tube 7, while ensuring that the clamping unit 2 has a simple structure and low cost.

[0059] 2) The shape of the inner side of the clamping piece 21 matches the shape of the outer side of the seed cryopreservation tube 7. This design ensures that the contact surfaces of the clamping piece 21 and the seed cryopreservation tube 7 can fit better, thereby improving the stability of the clamping. As a specific embodiment, the inner side of the clamping piece 21 is arc-shaped to match the cylindrical structure of the seed cryopreservation tube 7.

[0060] 3) The inner side of the clamping piece 21 is provided with multiple elastic protrusions 23 to increase the friction between the clamping piece 21 and the seed cryopreservation tube 7, thereby reducing the possibility of the structure accidentally falling off. Preferably, the elastic protrusions 23 are evenly distributed on the inner side of the clamping piece 21 to ensure that the seed cryopreservation tube 7 is subjected to uniform friction, thereby improving the stability of the seed cryopreservation tube 7 when clamped. More specifically, the protrusions are made of elastic material.

[0061] 4) The spike 22 is configured as a right-angled triangle with its base perpendicular to the clamping plate 21. When using this clamping assembly, this configuration facilitates the passing of the retaining ring 3 through the top of the seed cryopreservation tube 7 and then fitting it between adjacent spikes 22.

[0062] Example 5

[0063] Based on Examples 1-4, this example further improves the fixing ring 3 as follows:

[0064] 1) The inner side of the fixing ring 3 fits against the outer side of the spike 22. This facilitates the insertion of the fixing ring 3 through the spike 22 on the upper part of the clamping piece 21 and fixes it to the spike 22 at a suitable position according to the outer diameter of the seed cryopreservation tube 7, allowing for quick and convenient operation. It also ensures the stability of the fixing ring 3 clamping the seed cryopreservation tube 7. For example, the inner side of the fixing ring 3 is angled downwards to match the inclined surface of the spike 22 (i.e., the hypotenuse of a right triangle).

[0065] 2) The clamping assembly is made of an elastic material (phenyl silicone rubber or polyurethane elastomer) that is resistant to -90°C, to suit the storage environment (-80°C) of the seed cryopreservation tube 7.

[0066] Example 6

[0067] Based on Examples 1-5, this example provides a method for using the clamping assembly suitable for the seed cryopreservation tube 7, specifically including:

[0068] 1. Select a telescopic ring 1 with an inner diameter slightly larger than the outer diameter of the seed cryopreservation tube 7, and put the telescopic ring 1 on the outside of the seed cryopreservation tube 7, and tighten the female buckle 13 inward toward the male buckle 12.

[0069] 2. Adjust and make the inner side of the clamping piece 21 fit tightly against the outer wall of the seed cryopreservation tube 7;

[0070] 3. Select a fixing ring 3 with an inner diameter slightly larger than the outer diameter of the seed cryopreservation tube 7 and whose inner side can cooperate with the outer side of the barb 22 on the clamping unit 2. Pass the fixing ring 3 through the top of the seed cryopreservation tube 7 and then put it between the adjacent barb 22 so that the clamping assembly is reliably fixed on the seed cryopreservation tube 7, and then connect the chip used to store and retrieve seed information to the seed cryopreservation tube 7.

[0071] Fourth, the operator can indirectly grasp the seed cryopreservation tube 7 by contacting the telescopic ring 1 or the spike 22, thereby realizing the transfer of the seed cryopreservation tube 7, which facilitates the inventory of the seed bank and the verification / checking of seed information.

[0072] After verifying / checking the seed information, when the seeds are put into production, which is also the time when this clamping component ends its use, a grinding wheel is used to cut around the circumference of the seed cryopreservation tube 7 at the lower part (e.g., at the two-thirds position from top to bottom of the seed cryopreservation tube 7), forming a ring of grooves on the outer wall of the seed cryopreservation tube 7. Force is applied at the grooves to break the seed cryopreservation tube 7 into two pieces. This clamping component is located on the shorter section of the seed cryopreservation tube 7, while the longer section of the seed cryopreservation tube 7 contains the seeds. External force is used to expand or break the shorter section of the seed cryopreservation tube 7 to remove this clamping component, which can then be reused. In addition, the original information on this RFID chip can be cleared, allowing for repeated use.

Claims

1. A clamping assembly suitable for seed cryopreservation tubes, characterized in that: It includes a telescopic ring (1), a clamping unit (2) located on top of the telescopic ring (1), and a fixing ring (3) for fitting around the outside of the clamping unit (2), wherein, The telescopic ring (1) includes a connector (11), a female buckle (13) and a male buckle (12). The connector (11) is an elastic connector. The female buckle (13) and the male buckle (12) are respectively located at both ends of the connector (11). The female buckle (13) and the male buckle (12) cooperate with each other. When in use, the female buckle (13) and the male buckle (12) are fastened together to form a ring structure. The connector (11) is provided with an epitaxial sleeve (5) for inserting a chip. There are at least three clamping units (2), and a cavity I (4) is formed between the clamping units (2) to accommodate the seed cryopreservation tube (7); the clamping unit (2) includes a clamping piece (21) and a spike (22) for preventing the fixing ring (3) from retracting; there are at least two spikes (22), and the spikes (22) are arranged longitudinally on the outside of the clamping piece (21); the size of the spikes (22) gradually increases from top to bottom, and a cavity II (6) for limiting the fixing ring (3) is formed between adjacent spikes (22); The inner diameter of the fixing ring (3) is larger than the outer diameter of the seed cryopreservation tube (7), and the inner side of the fixing ring (3) matches the outer side of the clamping unit (2).

2. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The connector (11) is a flexible material connecting strip or a flexible material connecting piece, and the width of the connecting strip or connecting piece is 5-15mm.

3. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The female buckle (13) is provided with multiple slots (8) for limiting the male buckle (12).

4. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The outer sleeve (5) contains a chip for storing and retrieving seed information.

5. The clamping assembly for seed cryopreservation tubes according to claim 4, characterized in that: The chip is an RFID chip.

6. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The connector (11), the outer sleeve (5), and the clamping unit (2) are integrally formed.

7. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The clamping unit (2) consists of 3-6 units.

8. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The shape of the inner side of the clamping piece (21) matches the shape of the outer side of the seed cryopreservation tube (7).

9. The clamping assembly for seed cryopreservation tubes according to claim 8, characterized in that: The inner side of the clamping piece (21) is curved.

10. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The clamping piece (21) has multiple elastic protrusions (23) on its inner side.

11. The clamping assembly for seed cryopreservation tubes according to claim 10, characterized in that: The elastic protrusions (23) are evenly distributed on the inner side of the clamping piece (21).

12. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The spikes (22) are evenly distributed on the outside of the clamping plate (21).

13. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The spike (22) is a right-angled triangle, and the bottom surface of the spike (22) is perpendicular to the clamping plate (21).

14. The clamping assembly for seed cryopreservation tubes according to claim 1, characterized in that: The inner side of the fixing ring (3) is in contact with the outer side of the spike (22).

15. The clamping assembly for seed cryopreservation tubes according to any one of claims 1-14, characterized in that: The clamping assembly is a clamping assembly made of phenyl silicone rubber, or a clamping assembly made of polyurethane elastomer.

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